段志广｜西北大学｜学者主页

2026

Ginsenoside CK inhibits melanoma growth by promoting apoptosis and targeting cGAS-STING pathway to regulate the immune microenvironment

Haodong Tang, Ying Xu, Rongzhan Fu, Zhiguang Duan, Chenhui Zhu, Daidi Fan

Food Science and Human Wellness

2026

Engineered Chondrocalcin From Pichia pastoris : A Dual‐Functional Biomaterial for Cartilage Regeneration and Rheumatoid Arthritis Modulation

Wensha Zhu, Zilong Zhao, Weigang Yuwen, Linlin Qu, Zhiguang Duan, Chenhui Zhu, Daidi Fan

Biotechnology and Bioengineering

DOI

2025

Expression and Biological Activity of Recombinant Type IV Collagen

Yingxue Chang, Zhuo Zhang, Weigang Yuwen, Xu Ru, Rongzhan Fu, Chenhui Zhu, Weina Li, Zhiguang Duan, Daidi Fan

Journal of Agricultural and Food Chemistry

DOI

2025

Ginsenoside Rk3 Alleviates Neuroinflammation and Gastrointestinal Dysfunction in Parkinson’s Disease via Modulation of Gut Microbiota-Mediated Butyric Acid Metabolism

Sheng Zhou, Yuan Liu, Yannan Liu, Zhiguang Duan, Chenhui Zhu, Pan Wang, Rongzhan Fu

Journal of Agricultural and Food Chemistry

DOI

2025

Preparation, Characterization, and Functional Evaluation of a Novel Recombinant Hypoglycemic Protein with Multifunctional Effects

Tianzhu Liu, Xiaoxuan Ma, Zhiguang Duan

Journal of Agricultural and Food Chemistry

DOI

2023

稀有人参皂苷对CCl4所致小鼠急性肝损伤的保护作用

张言，李娜，黄蓉，傅容湛，段志广，范代娣

《化学试剂》

2022

Injectable Hydrogel Based on Defect‐Rich Multi‐Nanozymes for Diabetic Wound Healing via an Oxygen Self‐Supplying Cascade Reaction

Yang Li, Rongzhan Fu, Zhiguang Duan, Chenhui Zhu, Daidi Fan

Small

DOI

2021

人参皂苷的定向生物转化研究进展

赵婧，王盼，刘彦楠，傅荣湛，段志广，范代娣

《化工进展》

DOI

2021

Recent advances in systemic and local delivery of ginsenosides using nanoparticles and nanofibers

Jing Zhao, Zhiguang Duan, Xiaoxuan Ma, Yannan Liu, Daidi Fan

Chinese Journal of Chemical Engineering

2021

Adaptive Hydrogels Based on Nanozyme with Dual‐Enhanced Triple Enzyme‐Like Activities for Wound Disinfection and Mimicking Antioxidant Defense System

Yang Li, Rongzhan Fu, Zhiguang Duan, Chenhui Zhu, Daidi Fan

Advanced Healthcare Materials

DOI

2021

Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition

Xue Bai, Rongzhan Fu, Zhiguang Duan, Yannan Liu, Chenhui Zhu, Daidi Fan

Food & Function

DOI

2020

Purification, characterization, and hypoglycemic properties of eurocristatine from Eurotium cristatum spores in Fuzhuan brick tea

Gang Liu, Zhiguang Duan, Pan Wang, Daidi Fan, Chenhui Zhu

RSC Advances

DOI

2019

Ginsenoside Rk1 induces apoptosis and downregulates the expression of PD-L1 by targeting the NF-κB pathway in lung adenocarcinoma

Manling Hu, Jing Fan Yang, Linlin Qu, Xuqian Deng, Zhiguang Duan, Rongzhan Fu, Lihua Liang, Daidi Fan

Food & Function

DOI

2019

A Bi‐Layer PVA/CMC/PEG Hydrogel with Gradually Changing Pore Sizes for Wound Dressing

Yang Li, Chenhui Zhu, Daidi Fan, Rongzhan Fu, Pei Ma, Zhiguang Duan, Xian Li, Huan Lei, Lei Chi

Macromolecular Bioscience

DOI

2019

The protective effect of protopanaxatriol-type saponin on intestinal health in antibiotic-treated mice

Minxia Zhang, Jiaqi Zhao, Jianjun Deng, Zhiguang Duan, Chenhui Zhu, Daidi Fan

Food & Function

DOI

2019

Study on the hypnotic effect of rare protopanaxadiol-type and protopanaxatriol-type ginsenosides

Ning Mou, Zhiguang Duan, Pei Ma, Rongzhan Fu, Daidi Fan

RSC Advances

DOI

2018

稀有人参皂苷对实验性白癜风模型的影响

吴苑琪，刘魏征，范丽华，朱晨辉，段志广，范代娣

《西北大学学报(自然科学版)》

2018

High efficiency production of ginsenoside compound K by catalyzing ginsenoside Rb1 using snailase

Zhiguang Duan, Chenhui Zhu, Jingjing Shi, Daidi Fan, Jianjun Deng, Rongzhan Fu, Rong Huang, Cuiying Fan

Chinese Journal of Chemical Engineering

2018

Stability improvement of human collagen α1(I) chain using insulin as a fusion partner

Yu Mi, Yuan Gao, Daidi Fan, Zhiguang Duan, Rongzhan Fu, Lihua Liang, Wenjiao Xue, Shanshan Wang

Chinese Journal of Chemical Engineering

2018

Anti-anemia effects of ginsenoside Rk3 and ginsenoside Rh4 on mice with ribavirin-induced anemia

Bo Wei, Zhiguang Duan, Chenhui Zhu, Jianjun Deng, Daidi Fan

Food & Function

DOI

2017

毕赤酵母高密度发酵产Ⅲ型类人胶原蛋白及其胃粘膜修复功能

李伟娜，尚子方，段志广，李林波，贺婧，范代娣

《生物工程学报》

2017

相分离联合层析去除类人胶原蛋白中的内毒素

段志广，朱晨辉，张婧，范代娣

《化学工程》

2017

Anticancer effects of ginsenoside Rk3 on non-small cell lung cancer cells: in vitro and in vivo

Zhiguang Duan, Jianjun Deng, Yangfang Dong, Chenhui Zhu, Weina Li, Daidi Fan

Food & Function

DOI

2014

类人胶原蛋白-微孔淀粉的制备及生物学评价

蒙俊桦，王琪凯，范代娣，段志广，乔存存，王溢萍

《西北大学学报(自然科学版)》

2011

The Transdermal Absorption Study of Human-Like Collagen

Le Chang, Dai Di Fan, Zhiguang Duan, Li Ping Jia, Chen Hui Zhu, Xiao Xuan Ma, Yane Luo, Jun Feng Hui

Advanced materials research

DOI

2009

类人胶原蛋白-丝素蛋白血管支架的制备及性能表征

朱晨辉，范代娣，马晓轩，薛文娇，惠俊峰，陈岚，段志广，麻璞

《生物工程学报》

2009

Initial investigation of novel human‐like collagen/chitosan scaffold for vascular tissue engineering

Chenhui Zhu, Daidi Fan, Zhiguang Duan, Wenjiao Xue, Longan Shang, Fulin Chen, Yane Luo

Journal of Biomedical Materials Research Part A

DOI

2008

类人胶原蛋白止血海绵的性能研究

段志广

《西北大学》

2007

重组类人胶原蛋白Ⅱ膜的生物相容性

李荣，范代娣，朱晨辉，薛文娇，惠俊峰，段志广

《西北大学学报(自然科学版)》

2007

Biocompatibility of recombinant human-like collagen II membranes crosslinked with glutaraldehyde

Zhiguang Duan

Journal of Northwest University

精选作品

期刊论文

Ginsenoside CK inhibits melanoma growth by promoting apoptosis and targeting cGAS-STING pathway to regulate the immune microenvironment

Engineered Chondrocalcin From Pichia pastoris : A Dual‐Functional Biomaterial for Cartilage Regeneration and Rheumatoid Arthritis Modulation

Expression and Biological Activity of Recombinant Type IV Collagen

Ginsenoside Rk3 Alleviates Neuroinflammation and Gastrointestinal Dysfunction in Parkinson’s Disease via Modulation of Gut Microbiota-Mediated Butyric Acid Metabolism

Preparation, Characterization, and Functional Evaluation of a Novel Recombinant Hypoglycemic Protein with Multifunctional Effects

稀有人参皂苷对CCl4所致小鼠急性肝损伤的保护作用

Injectable Hydrogel Based on Defect‐Rich Multi‐Nanozymes for Diabetic Wound Healing via an Oxygen Self‐Supplying Cascade Reaction

人参皂苷的定向生物转化研究进展

Recent advances in systemic and local delivery of ginsenosides using nanoparticles and nanofibers

Adaptive Hydrogels Based on Nanozyme with Dual‐Enhanced Triple Enzyme‐Like Activities for Wound Disinfection and Mimicking Antioxidant Defense System

Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition

Purification, characterization, and hypoglycemic properties of eurocristatine from Eurotium cristatum spores in Fuzhuan brick tea

Ginsenoside Rk1 induces apoptosis and downregulates the expression of PD-L1 by targeting the NF-κB pathway in lung adenocarcinoma

A Bi‐Layer PVA/CMC/PEG Hydrogel with Gradually Changing Pore Sizes for Wound Dressing

The protective effect of protopanaxatriol-type saponin on intestinal health in antibiotic-treated mice

Study on the hypnotic effect of rare protopanaxadiol-type and protopanaxatriol-type ginsenosides

稀有人参皂苷对实验性白癜风模型的影响

High efficiency production of ginsenoside compound K by catalyzing ginsenoside Rb1 using snailase

Stability improvement of human collagen α1(I) chain using insulin as a fusion partner

Anti-anemia effects of ginsenoside Rk3 and ginsenoside Rh4 on mice with ribavirin-induced anemia

毕赤酵母高密度发酵产Ⅲ型类人胶原蛋白及其胃粘膜修复功能

相分离联合层析去除类人胶原蛋白中的内毒素

Anticancer effects of ginsenoside Rk3 on non-small cell lung cancer cells: in vitro and in vivo

类人胶原蛋白-微孔淀粉的制备及生物学评价

The Transdermal Absorption Study of Human-Like Collagen

类人胶原蛋白-丝素蛋白血管支架的制备及性能表征

Initial investigation of novel human‐like collagen/chitosan scaffold for vascular tissue engineering

类人胶原蛋白止血海绵的性能研究

重组类人胶原蛋白Ⅱ膜的生物相容性

Biocompatibility of recombinant human-like collagen II membranes crosslinked with glutaraldehyde

会议论文

Ⅰ型胶原蛋白与明胶制备止血膜的性能对比研究

预印本

Ginsenoside CK ameliorates non-alcoholic steatohepatitis by mediating oxidative stress attenuation and stimulating mitochondrial autophagy through NRF2 activation

Ginsenoside Rh4 alleviates skin fibrosis by targeting SIRT1 to activate the PGC-1α/Nrf2/HO-1 pathway

Synergistic Anticancer Therapy Via Injectable Nanoengineered Hydrogel-Mediated Disrupting of Redox Homeostasis and Induction of Ferroptosis/Apoptosis

Ginsenoside Rh4 Suppresses Colorectal Tumorigenesis Through the Modulation of Gut Microbiota-Mediated Bile Acid Metabolism

研究方向