百晓学者学者目录

吴艳玲

副研究员，复旦大学

精选作品

期刊论文

2026

垂盆草提取物介导AMPK/SIRT1/LXRs信号通路改善肝纤维化的作用机制

吴雨诺，王晨煜，崔振宇，廉丽花，南极星，吴艳玲

《中草药》

2026

Abstract 1777: FL116, a PD-1/IL-18 bispecific antibody, enables cis-activation of PD-1+ T cells and reshapes the suppressive tumor microenvironment (TME)

Haiming Huang, Quanxiao Li, Xiaotuan Zhang, Liwen Ji, Yanling Wu, Dong Wei, Tianlei Ying

Cancer Research

DOI

2026

Abstract 7779: A tunable interleukin-18 (IL-18) platform engineered for complete escape from the decoy receptor IL-18 binding protein (IL-18BP)

Haiming Huang, Wencong Peng, Ruohan Zhu, Quanxiao Li, Liwen Ji, Yao Lu, Dong Wei, Yanling Wu, Tianlei Ying

Cancer Research

DOI

2026

Abstract 7932: FL115, a novel IL-15 superagonist rationally designed to minimize safety risks for cancer immunotherapy

Quanxiao Li, Yaping Cheng, Dong Wei, Qiang Gao, Yanling Wu, Tianlei Ying

Cancer Research

DOI

2026

Development of human single-domain antibodies against influenza based on NA-targeting IgG

Ailing Huang, Cheng Li, Hui Wu, Hui Wu, Wenli Sun, Shanshan Huo, Juan Wang, Yanling Wu, Tianlei Ying, Fei Yu

Biochemical and Biophysical Research Communications

DOI

2025

化疗诱导的周围神经病变的发病机制及治疗进展

陆新，曲琳卓，王勇，关宏锏，吴艳玲

《中国药理学通报》

2025

酒精摄入对非酒精性脂肪肝发病进程的影响及潜在机制研究进展

朱昊清，吴艳玲，南极星，廉丽花

《中国药理学通报》

2025

NIR Ratiometric Fluorescent Antibody‐Drug Conjugate for Metastatic Ovarian Cancer Theranostics and Treatment Response Monitoring

Cheng Li, Zeyuan Yu, Tao Pu, Yanling Wu, Gang Wang, Youhua Xie, Tianlei Ying, Zhenlin Yang, Yibing Shi

Advanced Science

DOI

2025

A synergistic generative-ranking framework for tailored design of therapeutic single-domain antibodies

Yu Kong, Jiale Shi, Fandi Wu, Ting Zhao, Rubo Wang, Xiaoyi Zhu, Qingyuan Xu, Yidong Song, Quanxiao Li, Yulu Wang, Xingyu Gao, Yuedong Yang, Yi Feng, Zifei Wang, Weifeng Ge, Yanling Wu, Zhenlin Yang, Jianhua Yao, Tianlei Ying

Cell Discovery

DOI

2025

Nearly complete redirection of insertion-type indel into recombination enhances knock-in and facilitates endogenous biomolecular condensate analysis

Minglei Huang, Jingjing Fu, Peizhe Wang, Boyi Chen, Qichen Yuan, Jiawei Yu, Huimin Wang, Yiting Liu, Zhiyi Li, Yanling Wu, Tianlei Ying, Qingfeng Wu, Zhu Ming, Wei Qin, Yinqing Li

Cell Research

DOI

2025

Modulating Subcellular Localization to Preserve the Stability and Functionality of Intracellular Nanobodies

Wenli Sun, Keke Huang, Yaping Cheng, Ailing Huang, Yu Kong, Jun Lu, Tianlei Ying, Yanling Wu

Antibodies

DOI

2025

Oral Administration of Trifluoroacetyl Chitosan–Encapsulated Redshifted Immunofluorophore for NIR‐II Bioimaging of Colorectal Metastases

Yibing Shi, Xiaoyi Zhu, Qingyuan Xu, Yanling Wu, Yishuo Sun, Xin Zhao, Yulong Liu, Wei Feng, Youhua Xie, Tianlei Ying, Zhenlin Yang

Advanced Healthcare Materials

DOI

2025

Engineering a novel light-chain single-domain antibody to enable IgG-format bispecific antibody design

Mingkai Wang, Qingyuan Xu, Yu Kong, Yuxuan Zhong, Feng Yin, Litong Liu, Zhenlin Yang, Tianlei Ying, Yanling Wu

Antibody Therapeutics

DOI

2025

An IL-15-modified NKp30×HER2 trispecific NK cell engager enhances NK cell activation and tumor cell killing

Yaping Cheng, Quanxiao Li, Yu Kong, Ailing Huang, Zhenlin Yang, Tianlei Ying, Yanling Wu

Journal of Leukocyte Biology

DOI

2025

Inhaled bispecific single-domain antibody BM219 for mild-to-moderate COVID-19: a double-blind, randomized, placebo-controlled phase 2 trial

Yanling Wu, Yuan Li, Ping Zhang, Siwei Guo, Fang Yuan, Vivian Liu, Ting Yu, Feng Lin, Nan Yang, Chao Tu, Hongzhou Lu, Tianlei Ying, Xin Li

Cell Discovery

DOI

2025

Topical delivery of a human single-domain antibody targeting IL-33 to inhibit mucosal inflammation

Keke Huang, Yuqing Wu, Yuqing Wu, Yu Kong, Qingyuan Xu, Mingwei Lv, Yirou Zhang, Quanxiao Li, Quanxiao Li, Cheng Li, Wenping Song, Xiaoyi Zhu, Zhenlin Yang, Changchang Xin, Xujiao Zhou, Tianlei Ying, Yanling Wu, Yanling Wu, Jiaxu Hong

Cellular and Molecular Immunology

DOI

2025

Enhancing vaccine half-life as a novel strategy for improving immune response durability of subunit vaccines

Zhaoling Shen, Cheng Li, Wenping Song, Litong Liu, Yu Kong, Ailing Huang, Qingui Bao, Tianlei Ying, Yanling Wu

PLoS Pathogens

DOI

2024

Author Correction: Pretrainable geometric graph neural network for antibody affinity maturation

Huiyu Cai, Zuobai Zhang, Mingkai Wang, Bozitao Zhong, Quanxiao Li, Yuxuan Zhong, Yanling Wu, Tianlei Ying, Jian Tang

Nature Communications

DOI

2024

Pretrainable geometric graph neural network for antibody affinity maturation

Huiyu Cai, Zuobai Zhang, Mingkai Wang, Bozitao Zhong, Quanxiao Li, Yuxuan Zhong, Yanling Wu, Tianlei Ying, Jian Tang

Nature Communications

DOI

2024

Fully human single-domain antibody targeting a highly conserved cryptic epitope on the Nipah virus G protein

Yulu Wang, Yifang Sun, Zhaoling Shen, Cong Wang, Jun Qian, Qiyu Mao, Yajie Wang, Wenping Song, Yu Kong, Changyou Zhan, Zhenguo Chen, Dimiter Stanchev Dimitrov, Zhenlin Yang, Shibo Jiang, Fan Wu, Lu Lu, Tianlei Ying, Lei Sun, Yanling Wu

Nature Communications

DOI

2024

Half‐life extension of single‐domain antibody–drug conjugates by albumin binding moiety enhances antitumor efficacy

Quanxiao Li, Yu Kong, Yuxuan Zhong, Ailing Huang, Tianlei Ying, Yanling Wu

MedComm

DOI

2024

Identification and validation of anti-protein arginine methyltransferase 5 (PRMT5) antibody as a novel biomarker for systemic sclerosis (SSc)

Minrui Liang, Lingbiao Wang, Xiaolong Tian, Kun Wang, Xiaoyi Zhu, Linlin Huang, Qing Li, Wenjing Ye, Chen Chen, Haihua Yang, Wanqing Wu, Xiangjun Chen, Xiaoxia Zhu, Yu Xue, Weiguo Wan, Yanling Wu, Liwei Lu, Jiucun Wang, Hejian Zou, Tianlei Ying, Feng Zhou

Annals of the Rheumatic Diseases

DOI

2024

Antibody Nanotweezer Constructing Bivalent Transistor–Biomolecule Interface with Spatial Tolerance

Xuejun Wang, Kang Hua, Keke Huang, Mingquan Guo, Yanling Wu, Tianlei Ying, Yunqi Liu, Dacheng Wei

Nano Letters

DOI

2024

Progress in novel delivery technologies to improve efficacy of therapeutic antibodies

Wenli Sun, Yanling Wu, Tianlei Ying

Antiviral Research

DOI

2024

Single-domain antibodies as therapeutics for solid tumor treatment

Mingkai Wang, Tianlei Ying, Yanling Wu

Acta Pharmaceutica Sinica B

DOI

2024

Reforming solid tumor treatment: the emerging potential of smaller format antibody-drug conjugate

Xiaojie Ma, Mingkai Wang, Tianlei Ying, Yanling Wu

Antibody Therapeutics

DOI

2023

桦褐孔菌提取物介导LXRs信号通路调控肝纤维化

刘赛虎，窦佳艺，崔振宇，廉丽花，南极星，吴艳玲

《中国药理学通报》

2023

A novel human single-domain antibody-drug conjugate targeting CEACAM5 exhibits potent in vitro and in vivo antitumor activity

Xiaoyi Zhu, Quanxiao Li, Yu Kong, Keke Huang, Gang Wang, Yun-ji Wang, Jun Lu, Guoqiang Hua, Yanling Wu, Tianlei Ying

Acta Pharmacologica Sinica

DOI

2023

Defining a highly conserved cryptic epitope for antibody recognition of SARS-CoV-2 variants

Aihua Hao, Wenping Song, Cheng Li, Xiang Zhang, Chao Tu, Xun Wang, Pengfei Wang, Yanling Wu, Tianlei Ying, Lei Sun

Signal Transduction and Targeted Therapy

DOI

2023

Evaluation of vaccine effectiveness against SARS‐CoV‐2 variants by serological epitope profiling

Cheng Li, Zhenlin Yang, Yanling Wu, Tianlei Ying

Clinical and Translational Medicine

DOI

2022

白芷提取物及其活性成分欧前胡素改善痛风性关节炎

元明慧，姜禹辰，廉丽花，南极星，吴艳玲

《中国药理学通报》

2022

Inhalable antibodies for the treatment of COVID-19

Zhenlin Yang, Cheng Li, Yuanlin Song, Tianlei Ying, Yanling Wu

The Innovation

DOI

2022

First Nerve‐Related Immunoprobe for Guidance of Renal Denervation through Colocalization of NIR‐II and Photoacoustic Bioimaging

Shi Yibing, Minna Tang, Sidi Zhang, Chenchen Hu, Cheng Li, Quanxiao Li, Keke Huang, Song Wenping, Li Zhixing, Wenshu Li, Yang Zhenlin, Yanling Wu, Fuyou Li, Jialu Hu, Tianlei Ying

Advanced Healthcare Materials

DOI

2022

A Single Dose of Anti-HBsAg Antibody-Encoding mRNA-LNPs Suppressed HBsAg Expression: a Potential Cure of Chronic Hepatitis B Virus Infection

Binfan Chen, Yuchen Chen, Jian Li, Chunyu Wang, Wenping Song, Yumei Wen, Jinzhong Lin, Yanling Wu, Tianlei Ying

mBio

DOI

2022

Counter changes with changelessness: cope with SARS-CoV-2 immune evasion by targeting cryptic epitopes

Cheng Li, Tianlei Ying, Dimiter Stanchev Dimitrov, Yanling Wu

Life Medicine

DOI

2022

An antigen-strengthened dye-modified fully-human-nanobody-based immunoprobe for second near infrared bioimaging of metastatic tumors

Yibing Shi, Huifang Wu, Weiqiang Hu, Yujia Jin, Mengya Kong, Yulu Wang, Binfan Chen, Quanxiao Li, Keke Huang, Zhenlin Yang, Fuyou Li, Yanling Wu, Tianlei Ying

Biomaterials

DOI

2022

Single-Domain Antibodies as Therapeutics for Respiratory RNA Virus Infections

Keke Huang, Tianlei Ying, Yanling Wu

Viruses

DOI

2022

A highly stable human single-domain antibody-drug conjugate exhibits superior penetration and treatment of solid tumors

Yanling Wu, Quanxiao Li, Yu Kong, Zhi Wang, Cheng Lei, Ji Li, Lulu Ding, Chunyu Wang, Yaping Cheng, Yaozhu Wei, Yuanlin Song, Zhenlin Yang, Chao Tu, Yu Ding, Tianlei Ying

Molecular Therapy

DOI

2022

The prominent role of a CDR1 somatic hypermutation for convergent IGHV3-53/3-66 antibodies in binding to SARS-CoV-2

Xiaolong Tian, Xiaoyi Zhu, Wenping Song, Zhenlin Yang, Yanling Wu, Tianlei Ying

Emerging Microbes & Infections

DOI

2022

Half-Life Extension Enhances Drug Efficacy in Adeno-Associated Virus Delivered Gene Therapy

Huifang Wu, Dan Mei Hu, Quanxiao Li, Chunyu Wang, Xiaoyi Zhu, Wei Li, Binfan Chen, Ping Ji, Keke Huang, Ailing Huang, Jinghe Huang, Dimiter Stanchev Dimitrov, Yanling Wu, Tianlei Ying

Engineering

DOI

2022

Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody

Cheng Li, Wuqiang Zhan, Zhenlin Yang, Chao Tu, Gaowei Hu, Xiang Zhang, Wenping Song, Shujuan Du, Yuanfei Zhu, Keke Huang, Yu Kong, Meng Zhang, Qiyu Mao, Xiaodan Gu, Yi Zhang, Youhua Xie, Qiang Deng, Yuanlin Song, Zhenguo Chen, Lu Lu, Shibo Jiang, Yanling Wu, Lei Sun, Tianlei Ying

Cell

DOI

2022

Characterization of human IgM and IgG repertoires in individuals with chronic HIV-1 infection

Xiaolong Tian, Binbin Hong, Xiaoyi Zhu, Desheng Kong, Yumei Wen, Yanling Wu, Liying Ma, Tianlei Ying

Virologica Sinica

DOI

2022

Design of a Novel Fab‐Like Antibody Fragment with Enhanced Stability and Affinity for Clinical use (Small Methods 2/2022)

Chunyu Wang, Jiaxu Hong, Zhenlin Yang, Xujiao Zhou, Yuhan Yang, Yu Kong, Binfan Chen, Huifang Wu, Bin‐Zhi Qian, Dimiter Stanchev Dimitrov, Xingtao Zhou, Yanling Wu, Tianlei Ying

Small Methods

DOI

2022

A Toxin-Conjugated Recombinant Protein Targeting gp120 and gp41 for Inactivating HIV-1 Virions and Killing Latency-Reversing Agent-Reactivated Latent Cells

Xinling Wang, Wei Xu, Zezhong Liu, Yanling Wu, Qian Wang, Miao Cao, Tianlei Ying, Na He, Lu Lu, Shibo Jiang

mBio

DOI

2021

白桦酯酸介导STAT3信号通路调控肝纤维化进程

朱悦，高璐，廉丽花，南极星，吴艳玲

《中国药理学通报》

2021

Design of a Novel Fab‐Like Antibody Fragment with Enhanced Stability and Affinity for Clinical use

Chunyu Wang, Jiaxu Hong, Zhenlin Yang, Xujiao Zhou, Yuhan Yang, Yu Kong, Binfan Chen, Huifang Wu, Bin‐Zhi Qian, Dimiter Stanchev Dimitrov, Xingtao Zhou, Yanling Wu, Tianlei Ying

Small Methods

DOI

2021

Ultraprecise Antigen 10-in-1 Pool Testing by Multiantibodies Transistor Assay

Changhao Dai, Mingquan Guo, Yanling Wu, Banpeng Cao, Xuejun Wang, Yungen Wu, Hua Kang, Derong Kong, Zhaoqin Zhu, Tianlei Ying, Yunqi Liu, Dacheng Wei

Journal of the American Chemical Society

DOI

2021

A non-ACE2 competing human single-domain antibody confers broad neutralization against SARS-CoV-2 and circulating variants

Zhenlin Yang, Yulu Wang, Yujia Jin, Yuanfei Zhu, Yanling Wu, Cheng Li, Yu Kong, Wenping Song, Xiaolong Tian, Wuqiang Zhan, Ailing Huang, Shanshan Zhou, Shuai Xia, Xiaoxu Tian, Chao Peng, Cuicui Chen, Yibing Shi, Gaowei Hu, Shujuan Du, Yuyan Wang, Youhua Xie, Shibo Jiang, Lu Lu, Lei Sun, Yuanlin Song, Tianlei Ying

Signal Transduction and Targeted Therapy

DOI

2021

A Promising Intracellular Protein-Degradation Strategy: TRIMbody-Away Technique Based on Nanobody Fragment

Gang Chen, Yu Kong, You Li, Ailing Huang, Chunyu Wang, Shanshan Zhou, Zhenlin Yang, Yanling Wu, Jianke Ren, Tianlei Ying

Biomolecules

DOI

2021

Ultrasensitive Detection of SARS-CoV-2 Antibody by Graphene Field-Effect Transistors

Kang Hua, Xuejun Wang, Mingquan Guo, Changhao Dai, Renzhong Chen, Lei Yang, Yanling Wu, Tianlei Ying, Zhaoqin Zhu, Dapeng Wei, Dapeng Wei, Yunqi Liu, Dacheng Wei, Dacheng Wei

Nano Letters

DOI

2021

A novel and effective approach to generate germline-like monoclonal antibodies by integration of phage and mammalian cell display platforms

Yu-jia Jin, Diao Yu, Xiaolong Tian, Huixian Li, Xiao-Chao Zhou, Yu Kong, Wei Zhang, Lu Zhang, Lei Cheng, Zhenlin Yang, Chao Tu, Yanling Wu, Tianlei Ying

Acta Pharmacologica Sinica

DOI

2021

Potent germline-like monoclonal antibodies: rapid identification of promising candidates for antibody-based antiviral therapy

Xiaoyi Zhu, Fei Yu, Yanling Wu, Tianlei Ying

Antibody Therapeutics

DOI

2021

Synergistic Effect by Combining a gp120-Binding Protein and a gp41-Binding Antibody to Inactivate HIV-1 Virions and Inhibit HIV-1 Infection

Xinling Wang, Miao Cao, Yanling Wu, Wei Xu, Qian Wang, Tianlei Ying, Lu Lu, Shibo Jiang

Molecules

DOI

2021

The impact of receptor-binding domain natural mutations on antibody recognition of SARS-CoV-2

Cheng Li, Xiaolong Tian, Xiaodong Jia, Jinkai Wan, Lu Lu, Shibo Jiang, Fei Lan, Yinying Lu, Yanling Wu, Tianlei Ying

Signal Transduction and Targeted Therapy

DOI

2021

Insights into biological therapeutic strategies for COVID-19

Xiaolong Tian, Cheng Li, Yanling Wu, Tianlei Ying

Fundamental Research

DOI

2021

Enhancement versus neutralization by SARS-CoV-2 antibodies from a convalescent donor associates with distinct epitopes on the RBD

Yunjiao Zhou, Zezhong Liu, Shibo Li, S N Li, Wei Xu, Qianqian Zhang, Israel Tojal da Silva, Cheng Li, Yanling Wu, Qingling Jiang, Zhenmi Liu, Zhenmi Liu, Q Y Wang, Q Y Wang, Yu Guo, Di Qu, Chengjian Gu, Cai Xl, Di Qu, Christian T. Mayer, Xiangxi Wang, Shibo Jiang, Tianlei Ying, Zhenghong Yuan, Youhua Xie, Yumei Wen, Lu Lu, Qiao Wang, Qiao Wang

Cell Reports

DOI

2020

二氢槲皮素对高脂饲料联合酒精狂饮小鼠肝脏脂肪蓄积的干预机制

吴梅，乔春莹，叶欢，吴艳玲，南极星，廉丽花

《中国药理学通报》

2020

RBD-Fc-based COVID-19 vaccine candidate induces highly potent SARS-CoV-2 neutralizing antibody response

Zezhong Liu, Wei Xu, Shuai Xia, Chenjian Gu, Xinling Wang, Qian Wang, Jie Zhou, Yanling Wu, Xia Cai, Di Qu, Tianlei Ying, Youhua Xie, Lu Lu, Zhenghong Yuan, Shibo Jiang

Signal Transduction and Targeted Therapy

DOI

2020

Linear epitopes of SARS-CoV-2 spike protein elicit neutralizing antibodies in COVID-19 patients

Yang Li, Dan‐yun Lai, Hainan Zhang, He‐wei Jiang, Xiaolong Tian, Ming‐liang Ma, Huan Qi, Qingfeng Meng, Shujuan Guo, Yanling Wu, Wei Wang, Xiao Yi Yang, Dawei Shi, Junbiao Dai, Tianlei Ying, Jie Zhou, Sheng‐ce Tao

Cellular and Molecular Immunology

DOI

2020

Deep Mining of Human Antibody Repertoires: Concepts, Methodologies, and Applications

Xiaolong Tian, Cheng Li, Yanling Wu, Tianlei Ying

Small Methods

DOI

2020

Arming Anti-EGFRvIII CAR-T With TGFβ Trap Improves Antitumor Efficacy in Glioma Mouse Models

You Li, Huifang Wu, Gang Chen, Xiaofan Wei, Chunyu Wang, Shanshan Zhou, Ailing Huang, Zui Zhang, Changyou Zhan, Yanling Wu, Tianlei Ying

Frontiers in Oncology

DOI

2020

Human-IgG-Neutralizing Monoclonal Antibodies Block the SARS-CoV-2 Infection

Jinkai Wan, Shenghui Xing, Longfei Ding, Yongheng Wang, Chenjian Gu, Yanling Wu, Bowen Rong, Cheng Li, Siqing Wang, Kun Chen, Chenxi He, Dandan Zhu, Songhua Yuan, Chengli Qiu, Chen Zhao, Lei Nie, Zhangzhao Gao, Jingyu Jiao, Xiaoyan Zhang, Xiangxi Wang, Tianlei Ying, Haibin Wang, Youhua Xie, Yanan Lu, Jianqing Xu, Fei Lan

Cell Reports

DOI

2020

Identification of Human Single-Domain Antibodies against SARS-CoV-2

Yanling Wu, Cheng Li, Shuai Xia, Xiaolong Tian, Yu Kong, Zhi Wang, Chenjian Gu, Rong Zhang, Chao Tu, Youhua Xie, Zhenlin Yang, Lu Lu, Shibo Jiang, Tianlei Ying

Cell Host & Microbe

DOI

2020

Recent advances in “universal” influenza virus antibodies: the rise of a hidden trimeric interface in hemagglutinin globular head

Yulu Wang, Dan Hu, Yanling Wu, Tianlei Ying

Frontiers of Medicine

DOI

2020

Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein

Shuai Xia, Yun Zhu, Meiqin Liu, Qiaoshuai Lan, Wei Xu, Yanling Wu, Tianlei Ying, Shuwen Liu, Zhengli Shi, Shibo Jiang, Lu Lu

Cellular and Molecular Immunology

DOI

2020

Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody

Xiaolong Tian, Cheng Li, Ailing Huang, Shuai Xia, Sicong Lu, Zheng‐Li Shi, Lu Lu, Shibo Jiang, Zhenlin Yang, Yanling Wu, Tianlei Ying

Emerging Microbes & Infections

DOI

2019

Engineering a Novel Antibody-Peptide Bispecific Fusion Protein Against MERS-CoV

Lili Wang, Jiyan Xu, Yu Kong, Ruiying Liang, Wei Li, Jinyao Li, Jun Lu, Dimiter Stanchev Dimitrov, Fei Yu, Yanling Wu, Tianlei Ying

Antibodies

DOI

2019

Evaluation of antiviral - passive - active immunization (“sandwich”) therapeutic strategy for functional cure of chronic hepatitis B in mice

Bisheng Shi, Yanling Wu, Chunyu Wang, Xiaofang Li, Fan Yu, Bin Wang, Zhenlin Yang, Jianhua Li, Mifang Liang, Yu‐Mei Wen, Tianlei Ying, Zhenghong Yuan

EBioMedicine

DOI

2019

Rapid Elimination of Broadly Neutralizing Antibodies Correlates with Treatment Failure in the Acute Phase of Simian-Human Immunodeficiency Virus Infection

Yanling Wu, Jing Xue, Chunyu Wang, Wei Li, Lili Wang, Weizao Chen, Ponraj Prabakaran, Desheng Kong, Yujia Jin, Dan Hu, Yulu Wang, Lei Cheng, Diao Yu, Chao Tu, Ariola Bardhi, Igor A. Sidorov, Liying Ma, Harris Goldstein, Chuan Qin, Lu Lu, Shibo Jiang, Dimiter Stanchev Dimitrov, Tianlei Ying

Journal of Virology

DOI

2019

A broadly neutralizing germline-like human monoclonal antibody against dengue virus envelope domain III

Dan Hu, Zhongyu Zhu, Shun Li, Yong‐Qiang Deng, Yanling Wu, Nana Zhang, Vinita Puri, Chunyu Wang, Peng Zou, Lei Cheng, Xiaolong Tian, Yulu Wang, Qi Zhao, Wei Li, Ponraj Prabakaran, Yang Feng, Jane Cardosa, Cheng‐Feng Qin, Xiaohui Zhou, Dimiter Stanchev Dimitrov, Tianlei Ying

PLoS Pathogens

DOI

2018

miRNA Expression Profile of Saliva in Subjects of Yang Deficiency Constitution and Yin Deficiency Constitution

Yu Chen, Yanling Wu, H. Yao, Hui-qin Luo, Bing Lin, Xiuping Zhang, Xue Liang, Ranran Sun, Shi-Peng Zhao, Ying-Shuai Li, Yan-Fei Zheng, Ling-Ru Li, Qi Wang

Cellular Physiology and Biochemistry

DOI

2018

A ‘sandwich’ strategy promises functional cure of chronic hepatitis B

Lei Cheng, Yanling Wu, Tianlei Ying

Expert Review of Precision Medicine and Drug Development

DOI

2018

A defucosylated bispecific multivalent molecule exhibits broad HIV-1-neutralizing activity and enhanced antibody-dependent cellular cytotoxicity against reactivated HIV-1 latently infected cells

Desheng Kong, Yan Wang, Ping Ji, Wei Li, Tianlei Ying, Jinghe Huang, Chen Wang, Yanling Wu, Yanping Wang, Weizao Chen, Yanling Hao, Kunxue Hong, Yiming Shao, Dimiter Stanchev Dimitrov, Shibo Jiang, Liying Ma

AIDS

DOI

2018

In-Depth Analysis of Human Neonatal and Adult IgM Antibody Repertoires

Binbin Hong, Yanling Wu, Wei Li, Xun Wang, Yumei Wen, Shibo Jiang, Dimiter Stanchev Dimitrov, Tianlei Ying

Frontiers in Immunology

DOI

2017

Protective effect of Hua Tan Qu Shi decoction against liver injury in rats with nonalcoholic fatty liver disease.

Shi-Peng Zhao, Zhisheng Wu, Yu Chen, Xue Liang, Lei Bao, Pin Li, Ranran Sun, Yanling Wu, Ling-Ru Li, Qi Wang

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

DOI

2017

A Potent Germline-like Human Monoclonal Antibody Targets a pH-Sensitive Epitope on H7N9 Influenza Hemagglutinin

Fei Yu, Song He, Yanling Wu, So Young Chang, Lili Wang, Wei Li, Binbin Hong, Shuai Xia, Chunyu Wang, Surender Khurana, Yang Feng, Yanping Wang, Zhiwu Sun, Biao He, Dongni Hou, Jody F. Manischewitz, Lisa R. King, Yuanlin Song, Ji-Young Min, Hana Golding, Xinhua Ji, Lu Lu, Shibo Jiang, Dimiter Stanchev Dimitrov, Tianlei Ying

Cell Host & Microbe

DOI

2017

Single-Domain Antibodies As Therapeutics against Human Viral Diseases

Yanling Wu, Shibo Jiang, Tianlei Ying

Frontiers in Immunology

DOI

2017

Engineered Soluble Monomeric IgG1 Fc with Significantly Decreased Non-Specific Binding

Chunyu Wang, Yanling Wu, Lili Wang, Binbin Hong, Yujia Jin, Dan Hu, Gang Chen, Yu Kong, Ailing Huang, Guoqiang Hua, Tianlei Ying

Frontiers in Immunology

DOI

2017

One-domain CD4 Fused to Human Anti-CD16 Antibody Domain Mediates Effective Killing of HIV-1-Infected Cells

Wei Li, Yanling Wu, Desheng Kong, Hongjia Yang, Yanping Wang, Jiping Shao, Yang Feng, Weizao Chen, Liying Ma, Tianlei Ying, Dimiter Stanchev Dimitrov

Scientific Reports

DOI

2017

PotentIn VivoNK Cell-Mediated Elimination of HIV-1-Infected Cells Mobilized by a gp120-Bispecific and Hexavalent Broadly Neutralizing Fusion Protein

Ariola Bardhi, Yanling Wu, Weizao Chen, Wei Li, Zhongyu Zhu, Jian Hua Zheng, Hing C. Wong, Emily K. Jeng, Jennifer Jones, Christina Ochsenbauer, John C. Kappes, Dimiter Stanchev Dimitrov, Tianlei Ying, Harris Goldstein

Journal of Virology

DOI

2017

Escape from humoral immunity is associated with treatment failure in HIV-1-infected patients receiving long-term antiretroviral therapy

Yabo Ouyang, Qianqian Yin, Wei Li, Zhenpeng Li, Desheng Kong, Yanling Wu, Kunxue Hong, Hui Qin Xing, Yiming Shao, Shibo Jiang, Tianlei Ying, Liying Ma

Scientific Reports

DOI

2017

Neutralization of Zika virus by germline-like human monoclonal antibodies targeting cryptic epitopes on envelope domain III

Yanling Wu, Shun Li, Lanying Du, Chunyu Wang, Peng Zou, Binbin Hong, Mengjiao Yuan, Xiaonan Ren, Wanbo Tai, Yu Kong, Chen Zhou, Lu Lu, Xiaohui Zhou, Shibo Jiang, Tianlei Ying

Emerging Microbes & Infections

DOI

2016

Gene expression signatures for phlegm-dampness constitution of Chinese medicine

Ling-Ru Li, Juan Feng, H. Yao, Lan Xie, Yu Chen, Ling-Ling Yang, S. Hou, Shi-Peng Zhao, Ranran Sun, Yanling Wu, T. Bai, Ying-Shuai Li, Ruo-Xi Yu, Ji Wang, Qi Wang

Science China Life Sciences

DOI

2016

Efficacy and safety of Yinchenwuling powder for hyperlipidemia: a systematic review and Meta-analysis.

H. Yao, Zengliang Zhang, Ji Wang, Yu Chen, Li-Bing Zhu, Xiao-Ke Li, Zheng Yang, Zisong Wang, Ranran Sun, Xu Xu, Chang-Ming Li, Yanling Wu, Ling-Ru Li, Qi Wang, Jiacheng Zuo

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan

DOI

2016

From therapeutic antibodies to chimeric antigen receptors (CARs): making better CARs based on antigen-binding domain

Yanling Wu, Shibo Jiang, Tianlei Ying

Expert Opinion on Biological Therapy

DOI

2011

虎眼万年青总皂苷诱导活化肝星状细胞凋亡机制研究

吴艳玲，南极星

《亚太传统医药》

会议论文

2016

东北龙胆对小鼠暴发性肝衰竭的保护作用机制

张玉，夏凯丽，姜敏，郑金花，吴艳玲，南极星，廉丽花

《2016年第六届全国药物毒理学年会》

2016

中药有效成分治疗肝损伤及肝纤维化作用机制研究

吴艳玲，廉丽花，南极星

《2016年第六届全国药物毒理学年会》

预印本

2020

Antibody-dependent enhancement (ADE) of SARS-CoV-2 infection in recovered COVID-19 patients: studies based on cellular and structural biology analysis

Fan Wu, Renhong Yan, Mei Liu, Zezhong Liu, Yingdan Wang, Die Luan, Kaiyue Wu, Zhigang Song, Tingting Sun, Yunping Ma, Yuanyuan Zhang, Yuanyuan Zhang, Qimin Wang, Xiang Li, Ping Ji, Yaning Li, Cheng Li, Yanling Wu, Tianlei Ying, Yumei Wen, Shibo Jiang, Tongyu Zhu, Lu Lu, Yongzhen Zhang, Yongzhen Zhang, Qiang Zhou, Jinghe Huang

medRxiv

DOI

书籍章节

2026

Screening of Monoclonal Antibodies from Integrated Phage and Mammalian Cell Display Libraries

Diao Yu, Huixian Li, Yujia Jin, Yu Kong, Tianlei Ying, Yanling Wu, Chao Tu

Methods in molecular biology

DOI

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