朱心红｜南方医科大学｜学者主页

2026

青春期慢性应激调节小鼠成年期心理韧性的性别差异研究

任龙祥，袁心睿，戴永锋，吴玉，王广友，朱心红

《中国实验动物学报》

2026

Multimodal fusion of speech and PHQ-9 for machine learning-based adolescent depression screening.

Chen-Xi Wang, Ziyuan Zhang, Ze Liang, Zhuliang Yu, Jian Yang, Yongfeng Dai, Xinhong Zhu

Journal of Affective Disorders

DOI

2023

Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice

Yida Pan, Yuan Clare Zhang, Wen-ying Zheng, Minzhen Zhu, Huan-yu Li, Wen-jie Ouyang, Qin-Qing Wen, Xinhong Zhu

Journal of Neuroscience

DOI

2023

Enhancement of the liver’s neuroprotective role ameliorates traumatic brain injury pathology

Yongfeng Dai, Jing-Hua Dong, Yu Hsuan Wu, Minzhen Zhu, Wen‐Chao Xiong, Huanyu Li, Yulu Zhao, Bruce D. Hammock, Xinhong Zhu

Proceedings of the National Academy of Sciences

DOI

2023

Deletion of Transferrin Receptor 1 in Parvalbumin Interneurons Induces a Hereditary Spastic Paraplegia-Like Phenotype

Wen‐Cheng Xiong, Liqiang Jin, Yulu Zhao, Yu Hsuan Wu, Jing-Hua Dong, Zhixin Guo, Minzhen Zhu, Yongfeng Dai, Yida Pan, Xinhong Zhu

Journal of Neuroscience

DOI

2023

A thalamic-primary auditory cortex circuit mediates resilience to stress

Huan-Yu Li, Minzhen Zhu, Xinrui Yuan, Zhixin Guo, Yida Pan, Yuanqing Li, Xinhong Zhu

Cell

DOI

2022

Degradation of Perineuronal Nets in the Cerebellar Interpositus Nucleus Ameliorated Social Deficits in Shank3-deficient Mice

Peng Liu, Yulu Zhao, Wen‐Cheng Xiong, Yida Pan, Minzhen Zhu, Xinhong Zhu

Neuroscience

DOI

2022

Loss of schizophrenia-related miR-501-3p in mice impairs sociability and memory by enhancing mGluR5-mediated glutamatergic transmission

Wenquan Liang, Yu Hou, Weiyuan Huang, Yunqian Wang, Tingyun Jiang, Xingbing Huang, Zhongju Wang, Fengchun Wu, Jiawei Zheng, Jie Zhang, Haiyan Ou, Shuyun Li, Junjiao Ping, Yuan Zhang, Junping Ye, Zhongwei Li, Qiong Yang, Jian Zhang, Xianzhen Zheng, Shufen Li, Xinhong Zhu, Rongqing Chen, Cunyou Zhao

Science Advances

DOI

2021

The Ghrelin/Growth Hormone Secretagogue Receptor System Is Involved in the Rapid and Sustained Antidepressant-Like Effect of Paeoniflorin

Yuan Zhang, Minzhen Zhu, Xihe Qin, Yuanning Zeng, Xinhong Zhu

Frontiers in Neuroscience

DOI

2021

Upregulated NMDAR-enhanced GABAergic transmission underlies autistic-like deficits in Htr3a knockout mice

Lang Huang, Jing Wang, Guanmei Liang, Yue Gao, Shiyang Jin, Jian Hu, Xiaoxue Yang, Jianpei Lao, Jinfa Chen, Zhou-Cai Luo, Cui-Xia Fan, Li Xiong, Xinhong Zhu, Tianming Gao, Mei Zhong, Xinping Yang

Theranostics

DOI

2020

Acute EPA-induced learning and memory impairment in mice is prevented by DHA

Ji-Hong Liu, Qian Wang, Qiang-Long You, Zelin Li, Neng-Yuan Hu, Yan Wang, Zeng-Lin Jin, Shu-Ji Li, Xiaowen Li, Jian‐Ming Yang, Xinhong Zhu, Yifan Dai, Jiangping Xu, Xiaochun Bai, Tianming Gao

Nature Communications

DOI

2020

14,15-Epoxyeicosatrienoic Acid Alleviates Pathology in a Mouse Model of Alzheimer's Disease

Wenjun Chen, Mengyao Wang, Minzhen Zhu, Wen‐Chao Xiong, Xihe Qin, Xinhong Zhu

Journal of Neuroscience

DOI

2020

LncRNA-AC006129.1 reactivates a SOCS3-mediated anti-inflammatory response through DNA methylation-mediated CIC downregulation in schizophrenia

Chaoying Ni, Wei Jiang, Zhongju Wang, Zhuo Wang, Jian Zhang, Xianzhen Zheng, Zelin Liu, Haiyan Ou, Tingyun Jiang, Wenquan Liang, Fengchun Wu, Qiyang Li, Yu Hou, Qiong Yang, Bo Guo, Sihan Liu, Shuyun Li, Shufen Li, Ence Yang, Xinhong Zhu, Xingbing Huang, Zhexing Wen, Cunyou Zhao

Molecular Psychiatry

DOI

2019

Liver Soluble Epoxide Hydrolase Regulates Behavioral and Cellular Effects of Chronic Stress

Xihe Qin, Zhou Wu, Jing-Hua Dong, Yuanning Zeng, Wen‐Chao Xiong, Ce Liu, Mengyao Wang, Minzhen Zhu, Wenjun Chen, Yuan Zhang, Qiyuan Huang, Xinhong Zhu

Cell Reports

DOI

2019

Axonal iron transport in the brain modulates anxiety-related behaviors

Zhuo Wang, Yuanning Zeng, Peng Yang, Li-Qiang Jin, Wen‐Chao Xiong, Minzhen Zhu, Junzhe Zhang, Xiao Bing He, Xinhong Zhu

Nature Chemical Biology

DOI

2019

ABAD/17β-HSD10 reduction contributes to the protective mechanism of huperzine a on the cerebral mitochondrial function in APP/PS1 mice

Xiaodan Xiao, Qingzhuang Chen, Xinhong Zhu, Yong Wang

Neurobiology of Aging

DOI

2019

Astrocytic Epoxyeicosatrienoic Acid Signaling in the Medial Prefrontal Cortex Modulates Depressive-like Behaviors

Wen‐Chao Xiong, Xiong Cao, Yuanning Zeng, Xihe Qin, Minzhen Zhu, Jing Ren, Zhou Wu, Qiyuan Huang, Yuan Zhang, Mengyao Wang, Lianwan Chen, Gustavo Turecki, Naguib Mechawar, Wenjun Chen, Guo-Liang Yi, Xinhong Zhu

Journal of Neuroscience

DOI

2018

Removal of hERG potassium channel affinity through introduction of an oxygen atom: Molecular insights from structure-activity relationships of strychnine and its analogs

Chunhua Yuan, Zheng-Yi Luo, Ying Zhou, Sheng Lei, Changxi Xu, Chao Peng, Shuji Li, Xiaowen Li, Xinhong Zhu, Tianming Gao

Toxicology and Applied Pharmacology

DOI

2018

An improved Ultra-High Performance Liquid chromatography-tandem mass spectrometry method for simultaneous quantitation of cytochrome P450 metabolites of arachidonic acid in human plasma

Yan Zhang, Meng-Yao Wang, Qiyuan Huang, Minzhen Zhu, Jing Ren, Xiong Cao, Wen‐Chao Xiong, Xiao-Dan Xiao, Xinhong Zhu

Journal of Chromatography A

DOI

2018

CBX2 Inhibits Neurite Development by Regulating Neuron-Specific Genes Expression

Xi Gu, Wang Xuemin, Dazhuang Su, Xiaohong Su, Lifang Lin, Shuji Li, Qiaoqi Wu, Shuhu Liu, Peidong Zhang, Xinhong Zhu, Xiaodan Jiang

Frontiers in Molecular Neuroscience

DOI

2018

A negative feedback regulation of MTORC1 activity by the lysosomal Ca 2+ channel MCOLN1 (mucolipin 1) using a CALM (calmodulin)-dependent mechanism

Xue Jun Sun, Yi Yang, Xi Zoë Zhong, Qi Cao, Xinhong Zhu, Xinhong Zhu, Xiaojuan Zhu, Xiaojuan Zhu, Xian‐Ping Dong

Autophagy

DOI

2017

α2‐glycine receptors modulate adult hippocampal neurogenesis and spatial memory

Min‐Shan Lin, Wen‐Chao Xiong, Shuji Li, Zhi Gong, Xiong Cao, Xiao‐Jing Kuang, Yuan Zhang, Tianming Gao, Naguib Mechawar, Ce Liu, Xinhong Zhu

Developmental Neurobiology

DOI

2017

miR‐124 and miR‐9 mediated downregulation of HDAC5 promotes neurite development through activating MEF2C‐GPM6A pathway

Xi Gu, Congcong Fu, Lifang Lin, Shuhu Liu, Xiaohong Su, Aili Li, Qiaoqi Wu, Chunhong Jia, Peidong Zhang, Lu Chen, Xinhong Zhu, Wang Xuemin

Journal of Cellular Physiology

DOI

2015

MicroRNA124 Regulated Neurite Elongation by Targeting OSBP

Xi Gu, Aili Li, Shuhu Liu, Lifang Lin, Shuang Xu, Peidong Zhang, Shuji Li, Xiaowen Li, Bo Tian, Xinhong Zhu, Wang Xuemin

Molecular Neurobiology

DOI

2014

Soluble Epoxide Hydrolase Deficiency or Inhibition Attenuates MPTP-Induced Parkinsonism

Xiaocui Qin, Qiaoqi Wu, Lifang Lin, Ai-Min Sun, Shuhu Liu, Xiaowen Li, Xiong Cao, Tianming Gao, Pengcheng Luo, Xinhong Zhu, Wang Xuemin

Molecular Neurobiology

DOI

2014

Nuclear BK channels regulate gene expression via the control of nuclear calcium signaling

Boxing Li, Wei Jie, Lianyan Huang, Peng Wei, Shuji Li, Zheng-Yi Luo, Allyson K. Friedman, Andrea L. Meredith, Ming‐Hu Han, Xinhong Zhu, Tianming Gao

Nature Neuroscience

DOI

2013

Astrocyte-derived ATP modulates depressive-like behaviors

Xiong Cao, Liangping Li, Qian Wang, Qiong Wu, Hong-Hai Hu, Meng Zhang, Yingying Fang, Jie Zhang, Shu-Ji Li, Wen‐Cheng Xiong, Huacheng Yan, Yubo Gao, Jihong Liu, Xiaowen Li, Lirong Sun, Yuanning Zeng, Xinhong Zhu, Tianming Gao

Nature Medicine

DOI

2013

Astrocytic Adenosine 5′-Triphosphate Release Regulates the Proliferation of Neural Stem Cells in the Adult Hippocampus

Xiong Cao, Liangping Li, Xihe Qin, Shu-Ji Li, Meng Zhang, Qian Wang, Hong-Hai Hu, Yingying Fang, Yubo Gao, Xiaowen Li, Lirong Sun, Wen‐Cheng Xiong, Tianming Gao, Xinhong Zhu

Stem Cells

DOI

2012

抑郁神经生物学机制研究新进展

高宇博，李亮萍，朱心红，高天明

《生理学报》

2012

α-及γ-倒捻子素对U87细胞、PC12细胞增殖的影响

曾冰玲，鲁明明，李树基，孙丽荣，朱心红

《数理医药学杂志》

2012

An L-Type Calcium Channel Agonist, Bay K8644, Extends the Window of Intervention Against Ischemic Neuronal Injury

Hong-Hai Hu, Shu-Ji Li, Pu Wang, Huacheng Yan, Xiong Cao, Feng-qin Hou, Yingying Fang, Xinhong Zhu, Tianming Gao

Molecular Neurobiology

DOI

2011

Brain-derived neurotrophic factor signalling mediates antidepressant effects of lamotrigine

Nanxin Li, Xiaolu He, Yu Zhang, Xiaoli Qi, Huijie Li, Xinhong Zhu, Shuchang He

International Journal Of Neuropsychopharmacology，Vol. 140, No. 8

DOI

2011

小续命汤氯仿提取物的极性分离及其活性组分的筛选

杨树平，孙丽荣，朱心红

《数理医药学杂志》

2011

蛇床子素对L-和N-型钙通道的影响

袁春华，李勃兴，孙丽荣，朱心红

《现代生物医学进展》

2011

油炸马钱子的生物碱成分研究

孙丽荣，袁春华，李晓文，李树基，方莹莹，朱心红，高天明

《红河学院学报》

2011

升麻根茎的化学成分研究

孙丽荣，李晓文，李树基，方莹莹，袁春华，朱心红，高天明

《景德镇学院学报》

2011

Inhibition of human Nav1.5 sodium channels by strychnine and its analogs

Chunhua Yuan, Lirong Sun, Meng Zhang, Shuji Li, Wang Xuemin, Tianming Gao, Xinhong Zhu

Biochemical Pharmacology

DOI

2010

抑郁症动物模型的研究进展(英文)

严华成，曹雄，Manas Das，朱心红，高天明

Neuroscience Bulletin

2010

Behavioral animal models of depression

Huacheng Yan, Xiong Cao, Manas Kumar Das, Xinhong Zhu, Tianming Gao

Neuroscience Bulletin

DOI

2010

Fuzi polysaccharide-1 produces antidepressant-like effects in mice.

Hua-Cheng Yan, Hong-Da Qu, Li-Rong Sun, Shu-Ji Li, Xiong Cao, Ying-Ying Fang, W. Jie, Jonathan C. Bean, Wei-Kang Wu, Xinhong Zhu, Tian-Ming Gao

International Journal of Neuropsychopharmacology

DOI

2009

钾通道阻断剂四乙铵对氧葡萄糖剥夺诱导大鼠海马神经元死亡的保护作用

李树基，陈荷，陈明，李勃兴，朱心红，高天明

《新乡医学院学报》

2009

柿叶黄酮对大鼠急性前脑缺血再灌注损伤的保护作用

贝伟剑，李楚源，王德勤，彭文烈，朱心红

《广西中医药》

2008

Neuregulin-1温度依赖性抑制小鼠海马脑片CA1区的长时程增强

陈永君，张猛，王璞，朱心红，高天明

《南方医科大学学报》

2008

马钱子复合生物碱成分抑制成年大鼠海马神经前体细胞的分裂作用

龚芝，孙丽荣，曹雄，李树基，朱心红，高天明

《南方医科大学学报》

2008

煎煮时间和煎煮次数对三种芍药汤剂中芍药苷含量的影响

孙丽荣，严华成，曹雄，马骥，朱心红，高天明

《中国药物与临床》

2008

不同血浆样品制备方法对芍药苷血液药物浓度测定的影响

孙丽荣，严华成，曹雄，马骥，朱心红，高天明

《中国药物与临床》

2008

大鼠海马组织线粒体的蛋白质组学分析方法的建立

陈亮，严华成，王璞，李树基，朱心红，高天明

《神经解剖学杂志》

2008

BK8644对河豚毒素引起的大鼠海马锥体神经元AMPA受体介导的微小兴奋性突触后电流频率和幅度的影响

揭艳玲，李树基，行艳丽，龚芝，朱心红，高天明

《新乡医学院学报》

2008

BNIP3 expression is increased in the hippocampus of rats following transient global brain ischemia

Yanli Xing, Xinhong Zhu, Huacheng Yan, Pu Wang, Shu-Ji Li, Yan-ling Jie, Tianming Gao

Chinese Journal of Neuromedicine

DOI

2006

成年大鼠全脑缺血性脑损伤后神经前体细胞的增殖周期变化

李鸥，朱心红，高天明

《南方医科大学学报》

2005

L-型钙通道α1亚单位在成年鼠海马神经元上的差异性表达

杨建明，胡德辉，朱心红，高天明

《南方医科大学学报》

2005

成年大鼠海马神经前体细胞表达功能性的L-型钙通道

冯锦丽，胡德辉，陈明，田映红，施志敏，杨建明，朱心红，李晓文，高天明

《生物化学与生物物理进展》

2004

脑心通对大鼠脑缺血海马CA1区神经元损伤的保护作用

朱心红，杨建明，高天明

《南方医科大学学报》

2002

小续命汤与脑卒中——小续命汤之文献研究

朱心红，陈素云，高天明

《南方医科大学学报》

精选作品

期刊论文

青春期慢性应激调节小鼠成年期心理韧性的性别差异研究

Multimodal fusion of speech and PHQ-9 for machine learning-based adolescent depression screening.

Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice

Enhancement of the liver’s neuroprotective role ameliorates traumatic brain injury pathology

Deletion of Transferrin Receptor 1 in Parvalbumin Interneurons Induces a Hereditary Spastic Paraplegia-Like Phenotype

A thalamic-primary auditory cortex circuit mediates resilience to stress

Degradation of Perineuronal Nets in the Cerebellar Interpositus Nucleus Ameliorated Social Deficits in Shank3-deficient Mice

Loss of schizophrenia-related miR-501-3p in mice impairs sociability and memory by enhancing mGluR5-mediated glutamatergic transmission

The Ghrelin/Growth Hormone Secretagogue Receptor System Is Involved in the Rapid and Sustained Antidepressant-Like Effect of Paeoniflorin

Upregulated NMDAR-enhanced GABAergic transmission underlies autistic-like deficits in Htr3a knockout mice

Acute EPA-induced learning and memory impairment in mice is prevented by DHA

14,15-Epoxyeicosatrienoic Acid Alleviates Pathology in a Mouse Model of Alzheimer's Disease

LncRNA-AC006129.1 reactivates a SOCS3-mediated anti-inflammatory response through DNA methylation-mediated CIC downregulation in schizophrenia

Liver Soluble Epoxide Hydrolase Regulates Behavioral and Cellular Effects of Chronic Stress

Axonal iron transport in the brain modulates anxiety-related behaviors

ABAD/17β-HSD10 reduction contributes to the protective mechanism of huperzine a on the cerebral mitochondrial function in APP/PS1 mice

Astrocytic Epoxyeicosatrienoic Acid Signaling in the Medial Prefrontal Cortex Modulates Depressive-like Behaviors

Removal of hERG potassium channel affinity through introduction of an oxygen atom: Molecular insights from structure-activity relationships of strychnine and its analogs

An improved Ultra-High Performance Liquid chromatography-tandem mass spectrometry method for simultaneous quantitation of cytochrome P450 metabolites of arachidonic acid in human plasma

CBX2 Inhibits Neurite Development by Regulating Neuron-Specific Genes Expression

A negative feedback regulation of MTORC1 activity by the lysosomal Ca 2+ channel MCOLN1 (mucolipin 1) using a CALM (calmodulin)-dependent mechanism

α2‐glycine receptors modulate adult hippocampal neurogenesis and spatial memory

miR‐124 and miR‐9 mediated downregulation of HDAC5 promotes neurite development through activating MEF2C‐GPM6A pathway

MicroRNA124 Regulated Neurite Elongation by Targeting OSBP

Soluble Epoxide Hydrolase Deficiency or Inhibition Attenuates MPTP-Induced Parkinsonism

Nuclear BK channels regulate gene expression via the control of nuclear calcium signaling

Astrocyte-derived ATP modulates depressive-like behaviors

Astrocytic Adenosine 5′-Triphosphate Release Regulates the Proliferation of Neural Stem Cells in the Adult Hippocampus

抑郁神经生物学机制研究新进展

α-及γ-倒捻子素对U87细胞、PC12细胞增殖的影响

An L-Type Calcium Channel Agonist, Bay K8644, Extends the Window of Intervention Against Ischemic Neuronal Injury

Brain-derived neurotrophic factor signalling mediates antidepressant effects of lamotrigine

小续命汤氯仿提取物的极性分离及其活性组分的筛选

蛇床子素对L-和N-型钙通道的影响

油炸马钱子的生物碱成分研究

升麻根茎的化学成分研究

Inhibition of human Nav1.5 sodium channels by strychnine and its analogs

抑郁症动物模型的研究进展(英文)

Behavioral animal models of depression

Fuzi polysaccharide-1 produces antidepressant-like effects in mice.

钾通道阻断剂四乙铵对氧葡萄糖剥夺诱导大鼠海马神经元死亡的保护作用

柿叶黄酮对大鼠急性前脑缺血再灌注损伤的保护作用

Neuregulin-1温度依赖性抑制小鼠海马脑片CA1区的长时程增强

马钱子复合生物碱成分抑制成年大鼠海马神经前体细胞的分裂作用

煎煮时间和煎煮次数对三种芍药汤剂中芍药苷含量的影响

不同血浆样品制备方法对芍药苷血液药物浓度测定的影响

大鼠海马组织线粒体的蛋白质组学分析方法的建立

BK8644对河豚毒素引起的大鼠海马锥体神经元AMPA受体介导的微小兴奋性突触后电流频率和幅度的影响

BNIP3 expression is increased in the hippocampus of rats following transient global brain ischemia

成年大鼠全脑缺血性脑损伤后神经前体细胞的增殖周期变化

L-型钙通道α1亚单位在成年鼠海马神经元上的差异性表达

成年大鼠海马神经前体细胞表达功能性的L-型钙通道

脑心通对大鼠脑缺血海马CA1区神经元损伤的保护作用

小续命汤与脑卒中——小续命汤之文献研究

会议论文

NRG-1通过GABA能机制发挥神经保护作用

ZGF-2-130抑制小胶质细胞活化并保护脑缺血大鼠海马神经元死亡

终纹床核内源性NRG1对焦虑样行为的调节

脑缺血后海马CA1区caspase非依赖性凋亡相关蛋白表达水平的改变

通脉与黄芪不同配伍比例对大鼠前脑缺血/再灌流后海马CA1区神经元的再生作用

成年中枢神经再生的研究现状及应用前景

研究方向