百晓学者学者目录

刘扬中

副教授、博导、教授、讲师,中国科学技术大学

精选作品

期刊论文

2026

Rosmarinic Acid Is an hCtr1 Inhibitor that Interferes with Copper Transport Activity.

Fei Chen, Sisi Wu, Jian Kuang, Sijia Xiang, Shenghu Wang, Si-Ming Yuan, Kai-Ming Cao, Lu Yu, Wen-Ming Yang, Li-Qin Tang, Yang-Zhong Liu

Inorganic Chemistry

2026

A Ubiquinone-Reactive Pt(IV) Prodrug Perturbs Mitochondrial Metabolism for Selective Tumor Suppression.

Yi Dai, Wen-Xin Yu, Yi-Chen Yin, Fei Chen, Jing-Yun Zheng, Zhao-Lin Chen, Lei Zhang, Yang-Zhong Liu

ACS Applied Bio Materials

2026

Tumor-Directed Disulfidptosis via Spatiotemporally Controlled Copper Bioorthogonal Activation.

Yi-Chen Yin, Wen-Xin Yu, Zhen Shen, Siming Yuan, Kai-Ming Cao, Hong-Ke Liu, Yang-Zhong Liu

ACS Nano

2026

Synchronized ros burst and proteotoxicity in tumors: spatiotemporally guided cu-mof activates fenton-cuproptosis-dna damage cascade for tumor therapy

Cai-Xia Xia, Wei Tang, Yu Wang, Wen-Xin Yu, Yi-Chen Yin, Shun Lu, Yang-Zhong Liu, Siming Yuan, Li-Qin Tang

Journal of Nanobiotechnology

2025

Broad-Spectrum Suppression and Disassembly of α-Synuclein Variant Aggregates Mediated by a Ruthenium Metallodrug via Conserved Metal-Coordination

Shenghu Wang, Wei-Wei Wu, Lili Sun, Si-Ming Yuan, Wanqian Wei, Kai-Ming Cao, Yang-Zhong Liu

Inorganic Chemistry Frontiers

2025

Probing the interaction of cisplatin with calmodulin and its effect upon binding to myosin light-chain kinase

Si-Ming Yuan, Shenghu Wang, Kai-Ming Cao, Yu Wang, Hong-Ze Hu, Li-Qin Tang, Aizong Shen, Fabio Arnesano, G. Natile, Yang-Zhong Liu

Inorganic Chemistry Frontiers

2025

Provoking tumor disulfidptosis by single-atom nanozyme via regulating cellular energy supply and reducing power

Wen-Xin Yu, Duo Jin, Yajie Zhang, Shenghu Wang, Jia-Ji Yu, Man-Man Liu, Yi Dai, Yi-Chen Yin, Junjie Cheng, Yang-Zhong Liu

Nature Communications

2025

Metal-induced nanoscale clusterization initiates protein liquid-liquid phase separation.

Sijia Xiang, Zhuanghao Hou, Yu Wang, Yang Yang, Hong-Ze Hu, Changbao Yin, Guangming Huang, Kai-Ming Cao, Yang-Zhong Liu

Cell Reports

2024

A non-metal single atom nanozyme for cutting off the energy and reducing the power of tumors.

Junjie Cheng, Li Li, Duo Jin, Yajie Zhang, Wen-Xin Yu, Jia-Ji Yu, Jian-Hua Zou, Yi Dai, Yang Zhu, Man-Man Liu, Miya Zhang, Yongfu Sun, Yang-Zhong Liu, Xiaoyuan Chen

Angewandte Chemie

2024

Active Regulation of Protein Corona for Enhancing the in vivo Biodistribution and Metabolism of Nanoparticles

Duo Jin, Man-Man Liu, Yajie Zhang, Wen-Xin Yu, Jia-Ji Yu, Ying Luo, Junjie Cheng, Yang-Zhong Liu

Inorganic Chemistry Frontiers

2024

Reactions of Cisplatin with Thioredoxin-1 Regulate Intracellular Redox Homeostasis.

Shenghu Wang, Si-Ming Yuan, Hong-Ze Hu, Jiahai Zhang, Kai-Ming Cao, Yu Wang, Yang-Zhong Liu

Inorganic Chemistry

2024

Correction: Co-delivery of all-trans-retinoic acid enhances the anti-metastasis effect of albumin-bound paclitaxel nanoparticles.

Hai Huang, Hong-Dong Shi, Jing Liu, Yuan-Zeng Min, Yucai Wang, Andrew Z. Wang, Jun Wang, Yang-Zhong Liu

Chemical Communications

2024

Correction: Oral delivery of a platinum anticancer drug using lipid assisted polymeric nanoparticles.

Q. Cheng, Hong-Dong Shi, Hai Huang, Zhiting Cao, Jun Wang, Yang-Zhong Liu

Chemical Communications

2024

Enhancing Tumor Immunotherapy by Multivalent Anti‐PD‐L1 Nanobody Assembled via Ferritin Nanocage

Man-Man Liu, Duo Jin, Wen-Xin Yu, Jia-Ji Yu, Kai-Ming Cao, Junjie Cheng, Xiao-Hu Zheng, Andrew Z. Wang, Yang-Zhong Liu

Advancement of science

2024

Anti-PD-L1 nanobody guided in situ self-assembly and release of IOX1 and FDU for enhanced cancer chemo-immunotherapy

Yanyun Yang, Jia-Ji Yu, Man-Man Liu, Guang-Tao Zhang, Ronghua Zhao, Guiyuan Chen, Yi-Fan Huang, Yang-Zhong Liu, Yue Yuan

Nano Today

2024

A non‐metal single atom nanozyme for cutting off the energy and reducing power of tumors

Junjie Cheng, Li Li, Duo Jin, Yajie Zhang, Wenxin Yu, Jiaji Yu, Jianhua Zou, Yi Dai, Yang Zhu, Manman Liu, Miya Zhang, Yongfu Sun, Yangzhong Liu, Xiaoyuan Shawn Chen

Angewandte Chemie

2023

Gas-Mediated Tumor Energy Remodeling for Sensitizing Mild Photothermal Therapy.

Junjie Cheng, Yang Zhu, Yi Dai, Li Li, Miya Zhang, Duo Jin, Man-Man Liu, Jia-Ji Yu, Wen-Xin Yu, Dan Su, Jian-Hua Zou, Xiaoyuan Chen, Yang-Zhong Liu

Angewandte Chemie

2023

Cellular uptake of nickel by NikR is regulated by phase separation.

Kai-Ming Cao, Shixuan Li, Yu Wang, Hong-Ze Hu, Sijia Xiang, Qian-Ling Zhang, Yang-Zhong Liu

Cell Reports

2023

Mutual promotion of co-condensation of KRAS G-quadruplex and a well-folded protein HMGB1

Yu Wang, Kai-Ming Cao, Ming-Xi Zong, Si-Ming Yuan, Na Zhang, Yang-Zhong Liu

Nucleic Acids Research

2023

A Leaking-Proof Theranostic Nanoplatform for Tumor-Targeted and Dual-Modality Imaging-Guided Photodynamic Therapy

Duo Jin, Yang Zhu, Man-Man Liu, Wen-Xin Yu, Jia-Ji Yu, Xin-Wei Zheng, Lu-Lu Wang, Yun Wu, Kai-Ju Wei, Junjie Cheng, Yang-Zhong Liu

BME Frontiers

2023

Boosting Ferroptosis Therapy with Iridium Single‐Atom Nanocatalyst in Ultralow Metal Content

Junjie Cheng, Li Li, Duo Jin, Yi Dai, Yang Zhu, Jian-Hua Zou, Man-Man Liu, Wen-Xin Yu, Jia-Ji Yu, Yongfu Sun, Xiao-Yuan Chen, Yang-Zhong Liu

Advances in Materials

2023

Inter-Domain Repulsion of Dumbbell-Shaped Calmodulin during Electrospray Ionization Revealed by Molecular Dynamics Simulations.

Mou-Jun Luan, Zhuanghao Hou, Buchun Zhang, Likun Ma, Si-Ming Yuan, Yang-Zhong Liu, Guang-Ming Huang

Analytical Chemistry

2023

Peroxide-Simulating and GSH-Depleting Nanozyme for Enhanced Chemodynamic/Photodynamic Therapy via Induction of Multisource ROS.

Gang Liu, Mingyu Liu, Xiujing Li, Xiaorong Ye, Kai-Ming Cao, Yang-Zhong Liu, Yue Yu

ACS Applied Materials and Interfaces

2023

Cisplatin reacts with the RING finger domain of RNF11 and interferes with the protein functions.

Yu Wang, Si-Ming Yuan, Kai-Ming Cao, Yang-Zhong Liu

Metallomics

2023

Metabolite profiling and identification in living cells by coupling stable isotope tracing and induced electrospray mass spectrometry.

Zhuanghao Hou, Liujuan Zhan, Kai-Ming Cao, Mou-Jun Luan, Xinchen Wang, Buchun Zhang, Likun Ma, Hao Yin, Zhi-Cheng Liu, Yang-Zhong Liu, Guang-Ming Huang

Analytica Chimica Acta

2022

微量元素铜与人体生理功能和疾病

向思佳,刘扬中

《大学化学》

2022

α-Synuclein as a Target for Metallo-Anti-Neurodegenerative Agents.

Kai-Ming Cao, Yang Zhu, Zhuanghao Hou, Man-Man Liu, Yan-Yan Yang, Hong-Ze Hu, Yi Dai, Yu Wang, Si-Ming Yuan, Guang-Ming Huang, Jia-Ming Mei, P. Sadler, Yang-Zhong Liu

Angewandte Chemie

2022

Cuprous Ions can Disrupt Structure and Functions of the RING Finger Domain of RNF11

Yu Wang, Hong-Ze Hu, Si-Ming Yuan, Yunyan Li, Kai-Ming Cao, Hongbin Sun, Yang-Zhong Liu

Inorganic Chemistry Frontiers

2022

Native Mass Spectrometry for Peptide-Metal Interaction in Picoliter Cell Lysate.

Zhuanghao Hou, Mou-Jun Luan, Liujuan Zhan, Xinchen Wang, Si-Ming Yuan, Kai-Ming Cao, Yaping Sheng, Hao Yin, Yang-Zhong Liu, Guang-Ming Huang

Analytical Chemistry

2022

Photothermal Enhanced and Tumor Microenvironment Responsive Nanozyme for Amplified Cascade Enzyme Catalytic Therapy

Yang Zhu, Yuanbo Pan, Zhengxi Guo, Duo Jin, Wenyu Wang, Man-Man Liu, Ming-Xi Zong, Xin-Wei Zheng, Yun Wu, Lu-Lu Wang, Chang-Lin Tian, Junjie Cheng, Yang-Zhong Liu

Advanced Healthcare Materials

2022

Oxygen Self-Supply Engineering-Ferritin for the Relief of Hypoxia in Tumors and the Enhancement of Photodynamic Therapy Efficacy.

Yang Zhu, Duo Jin, Man-Man Liu, Yi Dai, Li Li, Xin-Wei Zheng, Lu-Lu Wang, Aizong Shen, Jianing Yu, Sisi Wu, Yun Wu, K. Zhong, Junjie Cheng, Yang-Zhong Liu

Small

2022

A low-swelling and toughened adhesive hydrogel with anti-microbial and hemostatic capacities for wound healing.

Liwei Zhang, Ya-Jie Zhang, Fan-Shu Ma, Xing-Zhu Liu, Yang-Zhong Liu, Yi Cao, R. Pei

Journal of materials chemistry. B

2022

Protein encapsulation of nanocatalysts: A feasible approach to facilitate catalytic theranostics.

Duo Jin, Man-Man Liu, Meng Zhang, Wen-Xin Yu, Jia-Ji Yu, Aizong Shen, Junjie Cheng, Yang-Zhong Liu

Advanced Drug Delivery Reviews

2022

Rapid Profiling of Metabolic Perturbations to Antibiotics in Living Bacteria by Induced Electrospray Ionization Mass Spectrometry.

Liujuan Zhan, Zhuanghao Hou, Yu Wang, Huimin Liu, Yang-Zhong Liu, Guang-Ming Huang

Journal of the American Society for Mass Spectrometry

2021

以人血清白蛋白为载体的Ru(III)和全反式维甲酸共运输纳米药物的构建及抗肿瘤转移作用

Xin Ding, Hong-Dong Shi, Yang-Zhong Liu

2021

Diatom-like silica-protein nanocomposites for sustained drug delivery of ruthenium polypyridyl complexes.

Hong-Dong Shi, Jingxue Lou, Simin Lin, Yi Wang, Yatao Hu, Ping-Yu Zhang, Yang-Zhong Liu, Qian-Ling Zhang

Journal of Inorganic Biochemistry

2021

Stimuli-Responsive Manganese Single-Atom Nanozyme for Tumor Therapy via Integrated Cascade Reactions.

Yang Zhu, Wenyu Wang, Junjie Cheng, Yun-Teng Qu, Yi Dai, Man-Man Liu, Jianing Yu, Cheng-Ming Wang, Hui-Juan Wang, Si-Cong Wang, Chao Zhao, Yuen Wu, Yang-Zhong Liu

Angewandte Chemie

2021

19F NMR Allows to Investigate the Fate of Platinum(IV) Prodrugs in Physiological Conditions.

Si-Ming Yuan, Yang Zhu, Yi Dai, Yu Wang, Duo Jin, Man-Man Liu, Li-Qin Tang, F. Arnesano, Yang-Zhong Liu, G. Natile

Angewandte Chemie

2021

Conjugation of oxaliplatin with PEGylated-nanobody for enhancing tumor targeting and prolonging circulation.

Li Li, Yang Zhu, Man-Man Liu, Duo Jin, Lei Zhang, Junjie Cheng, Yang-Zhong Liu

Journal of Inorganic Biochemistry

2021

Hemin-Caged Ferritin Acting as a Peroxidase-like Nanozyme for the Selective Detection of Tumor Cells.

Man-Man Liu, Yang Zhu, Duo Jin, Li Li, Junjie Cheng, Yang-Zhong Liu

Inorganic Chemistry

2021

NMR structural study on the self-trimerization of d(GTTAGG) into a dynamic trimolecular G-quadruplex assembly preferentially in Na+ solution with a moderate K+ tolerance

Hai-Tao Jing, Wen-Zhong Fu, Wenxuan Hu, Suping Xu, Xiao-Juan Xu, M. He, Yang-Zhong Liu, Na Zhang

Nucleic Acids Research

2021

Biocompatible Ruthenium Single-Atom Catalyst for Cascade Enzyme-Mimicking Therapy.

Wenyu Wang, Yang Zhu, Xiaorong Zhu, Ya-Fei Zhao, Zheng-Gang Xue, Can Xiong, Zhi-Yuan Wang, Yun-Teng Qu, Junjie Cheng, Min Chen, Man-Man Liu, Fang-Yao Zhou, Hao-Ran Zhang, Zheng Jiang, Yi-Dong Hu, Huang Zhou, Hui-Juan Wang, Ya-Fei Li, Yang-Zhong Liu, Yuen Wu

ACS Applied Materials and Interfaces

2021

Nanobody-A versatile tool for cancer diagnosis and therapeutics.

Man-Man Liu, Li Li, Duo Jin, Yang-Zhong Liu

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

2021

Nucleocapsid protein preferentially binds the stem-loop of duplex/quadruplex hybrid that unfolds the quadruplex structure.

Yaping Sheng, B. Cao, Mingxi Ou, Yu Wang, Si-Ming Yuan, Na Zhang, Tao-Tao Zou, Yang-Zhong Liu

Chemical Communications

2021

Rapid desalting during electrospray ionization mass spectrometry for investigating protein-ligand interactions in the presence of concentrated salts.

Yuting Chen, Si-Ming Yuan, Yang-Zhong Liu, Guang-Ming Huang

Analytica Chimica Acta

2021

Manganese-deposited iron oxide promotes tumor-responsive ferroptosis that synergizes the apoptosis of cisplatin

Junjie Cheng, Yang Zhu, Xin Xing, Jianmin Xiao, Hui Chen, Hong-Wei Zhang, Dan Wang, Yuan-Yuan Zhang, Gui-Long Zhang, Zheng-Yan Wu, Yang-Zhong Liu

Theranostics

2021

The Essential Trace Element Copper in Human Physiology and Pathology

Sijia Xiang, Yang-Zhong Liu

Daxue Huaxue

2021

19F NMR Allows the Investigation of the Fate of Platinum(IV) Prodrugs in Physiological Conditions

Siming Yuan, Yang Zhu, Yi Min Dai, Yu Wang, Duo Jin, Manman Liu, Liqin Tang, Fabio Arnesano, Giovanni Natile, Yangzhong Liu

Angewandte Chemie

2020

铂类抗肿瘤配合物的研究进展

朱阳,程珺洁,刘扬中

《药学进展》

2020

Combating metastasis of breast cancer cells with a carboplatin analogue containing an all-trans retinoic acid ligand.

Yi Dai, Hai Huang, Yang Zhu, Junjie Cheng, Ai-Zong Shen, Yang-Zhong Liu

Dalton Transactions

2020

Nanobody-Ferritin Conjugate for Targeted Photodynamic Therapy.

Man-Man Liu, Yang Zhu, Tian-Tian Wu, Junjie Cheng, Yang-Zhong Liu

Chemistry

2020

Nitric oxide-releasing platinum(IV) prodrug efficiently inhibits proliferation and metastasis of cancer cells.

Yi Dai, Yang Zhu, Junjie Cheng, Juan Shen, Hai Huang, Man-Man Liu, Zhao-Lin Chen, Yang-Zhong Liu

Chemical Communications

2020

NAMI-A preferentially reacts with the Sp1 protein: understanding the anti-metastasis effect of the drug.

Si-Ming Yuan, Siming Chen, Han Wu, Huan Jiang, Shihui Zheng, Qian-Ling Zhang, Yang-Zhong Liu

Chemical Communications

2020

Clustered nanobody-drug conjugates for targeted cancer therapy.

Tian-Tian Wu, Man-Man Liu, Hai Huang, Yaping Sheng, Hai-Hua Xiao, Yang-Zhong Liu

Chemical Communications

2020

A Dual Functional Nanoreactor for Synergistic Starvation and Photodynamic Therapy.

Yang Zhu, Hong-Dong Shi, Tuan-Wei Li, Jianing Yu, Zhengxi Guo, Junjie Cheng, Yang-Zhong Liu

ACS Applied Materials and Interfaces

2020

Cisplatin binds to the MDM2 RING finger domain and inhibits the ubiquitination activity.

Kai-Ming Cao, Xin-Liang Ding, Yaping Sheng, Yu Wang, Yang-Zhong Liu

Chemical Communications

2019

双酶修饰制备纳米抗体靶向成像蛋白簇

田瑶,武田田,刘扬中

《中国科学技术大学学报》

2019

铜转运蛋白hCtr1结合Cu(I)并转运至铜伴侣蛋白Atox1

卫浩,许德晨,崔杨,魏开举,袁斯明,刘扬中

《中国科学技术大学学报》

2019

Covalent versus Non-covalent Binding of Ruthenium η6-p-Cymene Complexes to Zinc-finger Protein NCp7.

Yaping Sheng, Zhuanghao Hou, Shiyong Cui, Kai-Ming Cao, Si-Ming Yuan, Mei Sun, Jakob Kljun, Guang-Ming Huang, I. Turel, Yang-Zhong Liu

Chemistry

2019

A Nanobody-Conjugated DNA Nanoplatform for Targeted Platinum Drug Delivery.

Tian-Tian Wu, Jian-Bing Liu, Man-Man Liu, Shaoli Liu, Shuai Zhao, Run Tian, Dengshuai Wei, Yang-Zhong Liu, Yao Zhao, Hai-Hua Xiao, Bao-Quan Ding

Angewandte Chemie

2019

Reaction of Histone H1 with trans-Platinum Complexes and the Effect on DNA Platination.

Lanjun Cheng, Chan Li, Si-Ming Yuan, Hong-Dong Shi, Lin-Hong Zhao, Lei Zhang, F. Arnesano, G. Natile, Yang-Zhong Liu

Inorganic Chemistry

2019

The facile and visualizable identification of broad-spectrum inhibitors of MDM2/p53 using co-expressed protein complexes.

Yang Yang, Zhiqiang Dong, Hong-Ze Hu, Jun-Hui Peng, Yaping Sheng, Y. Tong, Si-Ming Yuan, Zi-Gang Li, Jia-Xiang Yang, Thomas A Wells, Y. Qu, N. Farrell, Yang-Zhong Liu

In Analysis

2019

Charge-Selective Delivery of Proteins Using Mesoporous Silica Nanoparticles Fused with Lipid Bilayers.

Hong-Dong Shi, Shuzhang Liu, Junjie Cheng, Si-Ming Yuan, Yang Yang, Tiantian Fang, Kai-Ming Cao, Kai-Ju Wei, Qian-Ling Zhang, Yang-Zhong Liu

ACS Applied Materials and Interfaces

2019

Ultrafast Micro-Electrophoresis: Behind Direct Mass Spectrometry Measurements of Proteins and Metabolites in Living Cell/Cells.

Yuting Chen, Gongyu Li, Si-Ming Yuan, Yang Pan, Yang-Zhong Liu, Guang-Ming Huang

Analytical Chemistry

2019

Substrate Metabolism-Driven Assembly of High-Quality CdS xSe1- x Quantum Dots in Escherichia coli: Molecular Mechanisms and Bioimaging Application.

Li-Jiao Tian, Yuan Min, Wen-Wei Li, Jie-jie Chen, Nan-Qing Zhou, Ting-Ting Zhu, Dao-Bo Li, Jingyuan Ma, Peng-Fei An, Li-Rong Zheng, Hai Huang, Yang-Zhong Liu, Han-Qing Yu

ACS Nano

2019

New NSAID-Pt(IV) prodrugs to suppress metastasis and invasion of tumor cells and enhance anti-tumor effect in vitro and in vivo.

Xue-Qing Song, Zhong-Ying Ma, Yi-Gang Wu, M. Dai, Dong-Bo Wang, Jing-Yuan Xu, Yang-Zhong Liu

European journal of medicinal chemistry

2019

Cisplatin reacts with histone H1 and the adduct forms a ternary complex with DNA.

Lanjun Cheng, Chan Li, Zhaoyong Xi, Kai-Ju Wei, Si-Ming Yuan, F. Arnesano, G. Natile, Yang-Zhong Liu

Metallomics

2019

A dual functional ruthenium arene complex induces differentiation and apoptosis of acute promyelocytic leukemia cells

Hai Huang, Kai-Ming Cao, Ya-Qiong Kong, Si-Ming Yuan, Hong-Ke Liu, Yucai Wang, Yang-Zhong Liu

Chemical Science

2019

Cuprous binding promotes interaction of copper transport protein hCTR1 with cell membranes.

Yang Yang, Yang Zhu, Hong-Ze Hu, Lanjun Cheng, Man-Man Liu, G. Ma, Si-Ming Yuan, P. Cui, Yang-Zhong Liu

Chemical Communications

2019

Modular design of nanobody-drug conjugates for targeted-delivery of platinum anticancer drugs with an MRI contrast agent.

Hai Huang, Tian-Tian Wu, Hong-Dong Shi, Yun Wu, Hongyi Yang, K. Zhong, Yucai Wang, Yang-Zhong Liu

Chemical Communications

2019

Charge-dependent modulation of specific and nonspecific protein-metal ion interactions in nanoelectrospray ionization mass spectrometry.

Shihui Zheng, Si-Ming Yuan, Zhuanghao Hou, Gongyu Li, Yuting Chen, Yang Pan, Yang-Zhong Liu, Guang-Ming Huang

Rapid Communications in Mass Spectrometry

2019

Tetrathiomolybdate induces dimerization of the metal-binding domain of ATPase and inhibits platination of the protein

Tiantian Fang, Wanbiao Chen, Yaping Sheng, Si-Ming Yuan, Qiao-Wei Tang, Gongyu Li, Guang-Ming Huang, Ji-Hu Su, Xuan Zhang, J. Zang, Yang-Zhong Liu

Nature Communications

2018

铂类抗癌药物的多功能纳米递送体系

沈娟,朱阳,师红东,刘扬中

《化学进展》

2018

Selective Targeting of the Zinc Finger Domain of HIV Nucleocapsid Protein NCp7 with Ruthenium Complexes.

Yaping Sheng, Kai-Ming Cao, Ji Li, Zhuanghao Hou, Si-Ming Yuan, Guang-Ming Huang, Hong-Ke Liu, Yang-Zhong Liu

Chemistry

2018

Differential Reactivity of Metal Binding Domains of Copper ATPases towards Cisplatin and Colocalization of Copper and Platinum.

Tiantian Fang, Yao Tian, Si-Ming Yuan, Yaping Sheng, F. Arnesano, G. Natile, Yang-Zhong Liu

Chemistry

2018

Tetrathiomolybdate inhibits the reaction of cisplatin with human copper chaperone Atox1.

Yao Tian, Tiantian Fang, Si-Ming Yuan, Yu-Chuan Zheng, F. Arnesano, G. Natile, Yang-Zhong Liu

Metallomics

2018

A surface-display biohybrid approach to light-driven hydrogen production in air

Wei Wei, Peiqing Sun, Zhen Li, Kuisong Song, Wen-Yin Su, Bao Wang, Yang-Zhong Liu, Jing Zhao

Science Advances

2018

In Situ Living Cell Protein Analysis by Single-Step Mass Spectrometry.

Gongyu Li, Si-Ming Yuan, Shihui Zheng, Yang-Zhong Liu, Guang-Ming Huang

Analytical Chemistry

2018

Arsenic trioxide preferentially binds to the ring finger protein PML: understanding target selection of the drug.

Kai-Ming Cao, Yaping Sheng, Shihui Zheng, Si-Ming Yuan, Guang-Ming Huang, Yang-Zhong Liu

Metallomics

2018

Transglutaminase mediated PEGylation of nanobodies for targeted nano-drug delivery.

Tian-Tian Wu, Hai Huang, Yaping Sheng, Hong-Dong Shi, Yuan-Zeng Min, Yang-Zhong Liu

Journal of materials chemistry. B

2017

铂类抗肿瘤药物与蛋白质的作用机理

房田田,曹开明,程岚军,赵林泓,刘扬中

《中国科学:化学》

2017

Deciphering of interactions between platinated DNA and HMGB1 by hydrogen/deuterium exchange mass spectrometry.

Yuan-Yuan Wang, Zhi-Feng Du, Wei Zheng, Kui Wu, De-Chen Xu, Qun Luo, Yao Zhao, Juanjuan Han, Yang-Zhong Liu, Fuyi Wang

Dalton Transactions

2017

Cisplatin Preferentially Binds to Zinc Finger Proteins Containing C3H1 or C4 Motifs

Si-Ming Yuan, Xin-Liang Ding, Yang Cui, Kai-Ju Wei, Yu-Chuan Zheng, Yang-Zhong Liu

2017

Copper-finger protein of Sp1: the molecular basis of copper sensing.

Si-Ming Yuan, Siming Chen, Zhaoyong Xi, Yang-Zhong Liu

Metallomics

2017

Improved chemical synthesis of o-nirtrobenzyl-tyrosine for concise site-specific 15N-tyrosine NMR analysis demonstrated by plant ABA receptor PYL10

Xiao-Qi Guo, Bo Zhang, Yao He, Yang-Zhong Liu, Chang-Lin Tian

2017

The Effect of Salts in Promoting Specific and Competitive Interactions between Zinc Finger Proteins and Metals

Gongyu Li, Si-Ming Yuan, Shihui Zheng, Yuting Chen, Zhen Zheng, Yang-Zhong Liu, Guang-Ming Huang

Journal of the American Society for Mass Spectrometry

2017

Interactions between human copper chaperone Atox1 and cisplatin, carboplatin, nedaplatin and oxaliplatin studied by ESI mass spectrometry

Yu-Chuan Zheng, Zhaoyong Xi, Chan Li, Si-Ming Yuan, Chang-Jiang Li, Yang-Zhong Liu

2017

Multifunctional platinum-based nanoparticles for biomedical applications.

Q. Cheng, Yang-Zhong Liu

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

2017

Erratum to: Protein-protein interaction analysis in crude bacterial lysates using combinational method of 19F site-specific incorporation and 19F NMR

Dong Li, Yanan Zhang, Yao He, Chengwei Zhang, Jie-Fei Wang, Ying Xiong, Long-Hua Zhang, Yang-Zhong Liu, P. Shi, Chang-Lin Tian

Protein & Cell

2017

A sustainable biogenic route to synthesize quantum dots with tunable fluorescence properties for live cell imaging

Li-Jiao Tian, Nan-Qing Zhou, Xian-Wei Liu, Jinghai Liu, Xing Zhang, Hai Huang, Ting-Ting Zhu, Ling-Li Li, Qing-Fei Huang, Wen-Wei Li, Yang-Zhong Liu, Han-Qing Yu

2017

Protein interaction in the mechanism of platinum anticancer drugs

Tiantian Fang, Kai-Ming Cao, Lanjun Cheng, Lin-Hong Zhao, Yang-Zhong Liu

2017

Platinum transfer from hCTR1 to Atox1 is dependent on the type of platinum complex.

Xuelei Wu, Si-Ming Yuan, E. Wang, Y. Tong, G. Ma, Kai-Ju Wei, Yang-Zhong Liu

Metallomics

2016

Protein-protein interaction analysis in crude bacterial lysates using combinational method of 19F site-specific incorporation and 19F NMR

Dong Li, Yanan Zhang, Yao He, Chengwei Zhang, Jie-Fei Wang, Ying Xiong, Long-Hua Zhang, Yang-Zhong Liu, P. Shi, Chang-Lin Tian

Protein & Cell

2016

A comparative study on the interactions of human copper chaperone Cox17 with anticancer organoruthenium(II) complexes and cisplatin by mass spectrometry.

Lijie Li, Wei Guo, Kui Wu, Xuelei Wu, Lin-Hong Zhao, Yao Zhao, Qun Luo, Yuan-Yuan Wang, Yang-Zhong Liu, Qing-Wu Zhang, Fuyi Wang

Journal of Inorganic Biochemistry

2016

カチオン性脂質支援プロドラッグナノ粒子によるシスプラチンに対する腫瘍耐性の克服【Powered by NICT】

Zhiting Cao, Zhi-Yao Chen, Chun-Yang Sun, Hong-Jun Li, Hong-Xia Wang, Q. Cheng, Zu-Qi Zuo, Ji-Long Wang, Yang-Zhong Liu, Yu-Cai Wang, Jun Wang

2016

Binding States of Protein-Metal Complexes in Cells.

Gongyu Li, Si-Ming Yuan, Yang Pan, Yang-Zhong Liu, Guang-Ming Huang

Analytical Chemistry

2016

A dual-fluorescent nano-carrier for delivering photoactive ruthenium polypyridyl complexes.

Hong-Dong Shi, Tiantian Fang, Yao Tian, Hai Huang, Yang-Zhong Liu

Journal of materials chemistry. B

2016

Overcoming tumor resistance to cisplatin by cationic lipid-assisted prodrug nanoparticles.

Zhiting Cao, Zhi-Yao Chen, Chun-Yang Sun, Hong-Jun Li, Hong-Xia Wang, Q. Cheng, Zu-Qi Zuo, Ji-Long Wang, Yang-Zhong Liu, Yu-Cai Wang, Jun Wang

Biomaterials

2016

Asplatin enhances drug efficacy by altering the cellular response.

Q. Cheng, Hong-Dong Shi, Hongxia Wang, Jun Wang, Yang-Zhong Liu

Metallomics

2016

Co-delivery of all-trans-retinoic acid enhances the anti-metastasis effect of albumin-bound paclitaxel nanoparticles.

Hai Huang, Hong-Dong Shi, Jing Liu, Yuan-Zeng Min, Yucai Wang, Andrew Z. Wang, Jun Wang, Yang-Zhong Liu

Chemical Communications

2015

磷酸钙纳米体系用于顺铂前药的运载

曾冰茹,师红东,刘扬中

Journal of University of Science and Technology of China

2015

Human Serum Albumin Conjugated Nanoparticles for pH and Redox-Responsive Delivery of a Prodrug of Cisplatin.

Hong-Dong Shi, Q. Cheng, Si-Ming Yuan, Xin-Liang Ding, Yang-Zhong Liu

Chemistry

2015

The reaction of a platinated methionine motif of CTR1 with cysteine and histidine is dependent upon the type of precursor platinum complex.

G. Ma, Qin Wu, Xuelei Wu, F. Arnesano, G. Natile, E. Sletten, Yang-Zhong Liu

Journal of Inorganic Biochemistry

2015

A cell-penetrating protein designed for bimodal fluorescence and magnetic resonance imaging

Qin Wu, Q. Cheng, Si-Ming Yuan, J. Qian, K. Zhong, Y. Qian, Yang-Zhong Liu

Chemical Science

2015

A versatile pH-responsive platform for intracellular protein delivery using calcium phosphate nanoparticles.

Bingru Zeng, Hong-Dong Shi, Yang-Zhong Liu

Journal of materials chemistry. B

2015

Glutathione selectively modulates the binding of platinum drugs to human copper chaperone Cox17.

Lin-Hong Zhao, Zhen Wang, Han Wu, Zhaoyong Xi, Yang-Zhong Liu

Biochemical Journal

2015

Oral delivery of a platinum anticancer drug using lipid assisted polymeric nanoparticles.

Q. Cheng, Hong-Dong Shi, Hai Huang, Zhiting Cao, Jun Wang, Yang-Zhong Liu

Chemical Communications

2015

Effects of Buffers and pH on the Reaction of a trans‐Platinum Complex with 5′‐Guanosine Monophosphate

Chan Li, Yi Ding, Lanjun Cheng, Yu-Chuan Zheng, E. Sletten, Yang-Zhong Liu

2014

铜转运蛋白C端金属结合域与Ag+及Hg2+的相互作用

朱云城,王二琼,马国林,康彦彪,赵林泓,刘扬中

《物理化学学报》

2014

顺铂耐药的分子机制

郗照勇,刘扬中

《中国科学:化学》

2014

The reaction of arsenite with proteins relies on solution conditions.

Lin-Hong Zhao, Zhen Wang, Zhaoyong Xi, De-Chen Xu, Siming Chen, Yang-Zhong Liu

Inorganic Chemistry

2014

Conserved residues that modulate protein trans-splicing of Npu DnaE split intein.

Qin Wu, Zeng-Qiang Gao, Yong Wei, G. Ma, Yu-Chuan Zheng, Yu-Hui Dong, Yang-Zhong Liu

Biochemical Journal

2014

Rational Design of Polyion Complex Nanoparticles to Overcome Cisplatin Resistance in Cancer Therapy

Xianzhu Yang, Xiao-Jiao Du, Yang Liu, Yanhua Zhu, Yang-Zhong Liu, Ya-ping Li, Jun Wang

Advances in Materials

2014

Cisplatin binds to human copper chaperone Cox17: the mechanistic implication of drug delivery to mitochondria.

Lin Zhao, Q. Cheng, Zhen Wang, Zhaoyong Xi, De-Chen Xu, Yang-Zhong Liu

Chemical Communications

2014

保存アミノ酸残基はNpu DnaEスプリットインテインの蛋白質トランス-スプライシングを調節する

Qin Wu, Zheng-Qiang Gao, Yong Wei, G. Ma, Yu-Chuan Zheng, Yu-Hui Dong, Yang-Zhong Liu

2014

Transporting platinum drugs from a copper chaperone to ATPase: the mechanistic implication of drug efflux mediated cisplatin resistance

De-Chen Xu, Zhaoyong Xi, Lin-Hong Zhao, Yang-Zhong Liu

2014

A general chemiluminescence strategy for measuring aptamer-target binding and target concentration.

Shiyuan Li, Du-Yu Chen, Qingtong Zhou, Wei Wang, Ling-Feng Gao, Jie Jiang, Haojun Liang, Yang-Zhong Liu, G. Liang, H. Cui

Analytical Chemistry

2014

Copper binding modulates the platination of human copper chaperone Atox1 by antitumor trans-platinum complexes.

Zhaoyong Xi, Wei Guo, Chang-Lin Tian, Fuyi Wang, Yang-Zhong Liu

Metallomics

2014

Molecular mechanisms of cisplatin resistance

Zhaoyong Xi, Yang-Zhong Liu

2014

A Turn-Off Fluorescent Nanosensor for Iron in Aqueous Solution Based on Fluorescent Carbon Nanoparticles

Yu-Chuan Zheng, De-Chen Xu, Kai-Ju Wei, Daoli Zhao, Pingping Zhu, Yang-Zhong Liu

2014

The ligation of aspirin to cisplatin demonstrates significant synergistic effects on tumor cells.

Q. Cheng, Hong-Dong Shi, Hong Wang, Yuan-Zeng Min, Jun Wang, Yang-Zhong Liu

Chemical Communications

2013

钯配合物对结核杆菌RecA intein蛋白质剪接的抑制作用

刘嬿,吴芩,郑玉船,刘扬中

《高等学校化学学报》

2013

铜/镍金属伴侣蛋白的研究进展

阳新明,许德晨,程天凡,郗照勇,赵林泓,刘扬中,孙红哲

《化学进展》

2013

Chemical and cellular investigations of trans-ammine-pyridine-dichlorido-platinum(II), the likely metabolite of the antitumor active cis-diammine-pyridine-chorido-platinum(II).

De-Chen Xu, Yuan-Zeng Min, Q. Cheng, Hong-Dong Shi, Kai-Ju Wei, F. Arnesano, G. Natile, Yang-Zhong Liu

Journal of Inorganic Biochemistry

2013

Interaction between platinum complexes and the C-terminal motif of human copper transporter 1.

E. Wang, Zhaoyong Xi, Yan Li, Lianzhi Li, Lin-Hong Zhao, G. Ma, Yang-Zhong Liu

Inorganic Chemistry

2013

Interaction of C-Terminal Metal-Binding Domain of Copper Transport Protein with Ag + and Hg 2+

Yun-Cheng Zhu, E. Wang, G. Ma, Yan-Biao Kang, Lin-Hong Zhao, Yang-Zhong Liu

2013

Conserved residue modulates copper-binding properties through structural dynamics in human copper chaperone Atox1.

Zhaoyong Xi, C. Shi, Chang-Lin Tian, Yang-Zhong Liu

Metallomics

2013

Copper binding promotes the interaction of cisplatin with human copper chaperone Atox1.

Zhaoyong Xi, Wei Guo, Chang-Lin Tian, Fuyi Wang, Yang-Zhong Liu

Chemical Communications

2013

PtCl2(phen) disrupts the metal ions binding to amyloid-β peptide.

G. Ma, E. Wang, Hao Wei, Kai-Ju Wei, Pingping Zhu, Yang-Zhong Liu

Metallomics

2013

Tris-(2-carboxyethyl) phosphine significantly promotes the reaction of cisplatin with Sp1 zinc finger protein.

Siming Chen, Huan Jiang, Kai-Ju Wei, Yang-Zhong Liu

Chemical Communications

2012

Combating the drug resistance of cisplatin using a platinum prodrug based delivery system.

Yuan-Zeng Min, Chengqiong Mao, Siming Chen, G. Ma, Jun Wang, Yang-Zhong Liu

Angewandte Chemie

2012

Trans-platinum/thiazole complex interferes with Sp1 zinc-finger protein.

Siming Chen, De-Chen Xu, Huan Jiang, Zhaoyong Xi, Pingping Zhu, Yang-Zhong Liu

Angewandte Chemie

2012

Copper(I) coordination polymers of 2,2'-dipyridylamine derivatives: syntheses, structures, and luminescence.

Jia Ni, Kai-Ju Wei, Yuan-Zeng Min, Yao-Wen Chen, Shun-Ze Zhan, Dan Li, Yang-Zhong Liu

Dalton Transactions

2012

Synthesis of a ratiometric fluorescent peptide sensor for the highly selective detection of Cd2+.

Yan Li, Lianzhi Li, Xue-Wei Pu, G. Ma, E. Wang, Jinming Kong, Zhi-Peng Liu, Yang-Zhong Liu

Bioorganic & Medicinal Chemistry Letters

2012

Selectivity of arsenite interaction with zinc finger proteins.

Lin-Hong Zhao, Siming Chen, Liang-Yuan Jia, Shi Shu, Pingping Zhu, Yang-Zhong Liu

Metallomics

2012

Anti-cancer medicinal aspirin platinum complex and preparation method thereof

Yang-Zhong Liu, Hong-Dong Shi, Yuan-Zeng Min, Q. Cheng

2012

Mutual synergistic protein folding in split intein

Yu-Chuan Zheng, Qin Wu, Chun-Yu Wang, Min-Qun Xu, Yang-Zhong Liu

Bioscience Reports

2012

A novel fluorescent probe for Au(III)/Au(I) ions based on an intramolecular hydroamination of a Bodipy derivative and its application to bioimaging.

Jian-bo Wang, Qingqing Wu, Yuan-Zeng Min, Yang-Zhong Liu, Qin-Hua Song

Chemical Communications

2012

Self-assembled hetero-bimetallic sandwich with Ag–Ag bridging using a flexible two-arm ferrocene amide linker

Jia Ni, Kai-Ju Wei, Yaowen Chen, Yang-Zhong Liu

2011

Identification of [PtCl2(phen)] binding modes in amyloid-β peptide and the mechanism of aggregation inhibition.

G. Ma, Fan Huang, Xue-Wei Pu, Liang-Yuan Jia, Tao Jiang, Lianzhi Li, Yang-Zhong Liu

Chemistry

2011

Effect of thioethers on DNA platination by trans-platinum complexes.

Chan Li, Rongrong Huang, Yi Ding, E. Sletten, F. Arnesano, Maurizio Losacco, G. Natile, Yang-Zhong Liu

Inorganic Chemistry

2011

pKa Coupling at the Intein Active Site: Implications for the Coordination Mechanism of Protein Splicing with a Conserved Aspartate

Zhenming Du, Yu-Chuan Zheng, Melissa A. Patterson, Yang-Zhong Liu, Chun-Yu Wang

Journal of the American Chemical Society

2011

Cu(L-His)2溶液配位结构的X射线吸收精细结构分析

Yan Pan, Li-Yun Zhang, Yang-Zhong Liu

2011

XAFS Study of Coordination Structure of Cu(L-His)2 in Solution

Yan Pan, Li-Yun Zhang, Yang-Zhong Liu

2010

Backbone Dynamics and Global Effects of an Activating Mutation in Minimized Mtu RecA Inteins

Zhenming Du, Yang-Zhong Liu, D. Ban, Maria M. Lopez, M. Belfort, Chun-Yu Wang

Journal of Molecular Biology

2010

Binding and inhibition of copper ions to RecA inteins from Mycobacterium tuberculosis.

Li-Yun Zhang, Ning Xiao, Yan Pan, Yu-Chuan Zheng, Z. Pan, Zhao-Feng Luo, Xiaolong Xu, Yang-Zhong Liu

Chemistry

2010

Heterobimetallic metal-complex assemblies constructed from the flexible arm-like ligand 1,1'-bis[(3-pyridylamino)carbonyl]ferrocene: structural versatility in the solid state.

Kai-Ju Wei, Jia Ni, Yang-Zhong Liu

Inorganic Chemistry

2010

Cisplatin Inhibits Protein Splicing, Suggesting Inteins as Therapeutic Targets in Mycobacteria*

Li-Yun Zhang, Yu-Chuan Zheng, B. Callahan, M. Belfort, Yang-Zhong Liu

Journal of Biological Chemistry

2010

Silver Coordination Polymers Based on Neutral Trinitrile Ligand: Topology and the Role of Anion

Jia Ni, Kai-Ju Wei, Yang-Zhong Liu, Xiao-Chun Huang, Dan Li

2010

Small-molecule reductants inhibit multicatalytic activity of AA-NADase from Agkistrodon acutus venom by reducing the disulfide-bonds and Cu(II) of enzyme.

Li-Yun Zhang, Xiaolong Xu, Zhao-Feng Luo, Hao Wu, Deng-Ke Shen, Li Peng, Yang-Zhong Liu

Biopolymers

2010

Gold nanorods for platinum based prodrug delivery.

Yuan-Zeng Min, Chengqiong Mao, De-Chen Xu, Jun Wang, Yang-Zhong Liu

Chemical Communications

2010

Solvent-induced two heterometallic coordination polymers based on a flexible ferrocenyl ligand

Chun-Yan Cao, Kai-Ju Wei, Jia Ni, Yang-Zhong Liu

2010

Thioether binding mediates monofunctional platinum antitumor reagents to trans configuration in DNA interactions.

G. Ma, Yuan-Zeng Min, Fan Huang, Tao Jiang, Yang-Zhong Liu

Chemical Communications

2009

Methionine can favor DNA platination by trans-coordinated platinum antitumor drugs.

Chan Li, Zhan-Yong Li, E. Sletten, F. Arnesano, Maurizio Losacco, G. Natile, Yang-Zhong Liu

Angewandte Chemie

2009

Highly Conserved Histidine Plays a Dual Catalytic Role in Protein Splicing: a pKa Shift Mechanism

Zhenming Du, Philip T. Shemella, Yang-Zhong Liu, S. McCallum, Brian Pereira, S. Nayak, G. Belfort, M. Belfort, Chun-Yu Wang

Journal of the American Chemical Society

2009

Metal Ions Binding to RecA Inteins from Mycobacterium tuberculosis

Li-Yun Zhang, Yu-Chuan Zheng, Zhaoyong Xi, Zhao-Feng Luo, Xiaolong Xu, Chun-Yu Wang, Yang-Zhong Liu

Molecular Biosystems

2009

Cytotoxic trans-oriented iminoether platinum complexes – Kinetics of binding to DNA oligonucleotides determined by 15N NMR spectroscopy

Cecilie Alvheim, N. A. Frøystein, Jo Vinje, F. Intini, G. Natile, Yang-Zhong Liu, Rong-Fu Huang, E. Sletten

2008

1H NMR study of the effect of variable ligand on heme oxygenase electronic and molecular structure

Li-Hua Ma, Yangzhong Liu, Xu-Hong Zhang, Tadashi Yoshida, G. L. la Mar

Journal of Inorganic Biochemistry

2008

1H, 13C, and 15N NMR assignments of an engineered intein based on Mycobacterium tuberculosis RecA

Zhenming Du, Yang-Zhong Liu, Yu-Chuan Zheng, S. McCallum, J. Dansereau, V. Derbyshire, M. Belfort, G. Belfort, P. van Roey, Chun-Yu Wang

Biomolecular NMR Assignments

2007

Self-assembled hetero-bimetallic coordination cage and cation-clusters with micro(2)-Cl bridging using a flexible two-arm ferrocene amide linker.

Kai-Ju Wei, Jia Ni, Yong-shu Xie, Yang-Zhong Liu, Qing-Liang Liu

Dalton Transactions

2007

Surface plasmon resonance and nuclear magnetic resonance studies of ABAD-Abeta interaction.

Yi-Lin Yan, Yang-Zhong Liu, Mirco Sorci, G. Belfort, J. Lustbader, S. Yan, Chun-Yu Wang

Biochemistry

2007

Self‐Assembly of Silver(I) Coordination Polymers from AgX (X = BF4–, ClO4–, CF3COO–, and SO3CF3–) and a Rigid Bent 3,6‐Dicyano‐9‐phenylcarbazole Ligand: The Templating Effect of Anions

Kai-Ju Wei, Jia Ni, Jian Gao, Yang-Zhong Liu, Qing-Liang Liu

2006

1H NMR study of the magnetic properties and electronic structure of the hydroxide complex of substrate-bound heme oxygenase from Neisseria meningitidis: influence of the axial water deprotonation on the distal H-bond network.

Li-Hua Ma, Yangzhong Liu, Xuhang Zhang, Tadashi Yoshida, G. L. la Mar

Journal of the American Chemical Society

2006

Characterization of the spontaneous "aging" of the heme oxygenase from the pathological bacterium Neisseria meningitidis via cleavage of the C-terminus in contact with the substrate. Implications for functional studies and the crystal structure.

Yangzhong Liu, Li-Hua Ma, Xu-Hong Zhang, Tadashi Yoshida, J. Satterlee, G. L. la Mar

Biochemistry

2006

Modulation of the axial water hydrogen-bonding properties by chemical modification of the substrate in resting state, substrate-bound heme oxygenase from Neisseria meningitidis; coupling to the distal H-bond network via ordered water molecules.

Li-Hua Ma, Yangzhong Liu, Xu-Hong Zhang, Tadashi Yoshida, K. Langry, Kevin M. Smith, G. L. la Mar

Journal of the American Chemical Society

2006

1H NMR Study of the influence of hemin vinyl-->methyl substitution on the interaction between the C-terminus and substrate and the "aging" of the heme oxygenase from Neisseria meningitidis: induction of active site structural heterogeneity by a two-fold symmetric hemin.

Yangzhong Liu, Li-Hua Ma, Xu-Hong Zhang, Tadashi Yoshida, J. Satterlee, G. L. la Mar

Biochemistry

2006

P3–379: Characterizing the interaction between ABAD and Aβ using surface plasma resonance and nuclear magnetic resonance

Chun-Yu Wang, Yi-Lin Yan, Yang-Zhong Liu, S. Yan, Hong-Wei Xu

2005

Solution 1H NMR characterization of the distal H-bond network and the effective axial field in the resting-state, high-spin ferric, substrate-bound complex of heme oxygenase from N. meningitidis.

Yangzhong Liu, Xu-Hong Zhang, Tadashi Yoshida, G. L. la Mar

Journal of the American Chemical Society

2004

1H NMR characterization of the solution active site structure of substrate-bound, cyanide-inhibited heme oxygenase from Neisseria meningitidis: comparison to crystal structures.

Yangzhong Liu, Xu-Hong Zhang, Tadashi Yoshida, G. L. la Mar

Biochemistry

2003

Interaction between macrocyclic nickel complexes and the nucleotides GMP, AMP and ApG.

Yang-Zhong Liu, E. Sletten

Journal of Inorganic Biochemistry

2002

Formation of adenine-N3/guanine-N7 cross-link in the reaction of trans-oriented platinum substrates with dinucleotides.

Yang-Zhong Liu, Jo Vinje, C. Pacifico, G. Natile, E. Sletten

Journal of the American Chemical Society

2002

Kinetic study of the reaction between an antitumor 15N labeled trans-platinum iminoether complex and GMP by [1H, 15N] HMQC NMR

Yang-Zhong Liu, F. Intini, G. Natile, E. Sletten

2001

Antitumor trans Platinum Complexes can Form Cross-Links with Adjacent Purine Groups Financial support by the European Commission BIOMED II program (Contract BMH4-CT97-2485) and COST (D8/007/97 and D8/012/97) are gratefully acknowledged. Thanks are extended to the Norwegian Research Council (Contract

Yang-Zhong Liu, C. Pacifico, G. Natile, E. Sletten

Angewandte Chemie

2001

Cytostatisch wirkende trans‐Platinkomplexe können Querverknüpfungen zu angrenzenden Purinresten bilden

Yang-Zhong Liu, C. Pacifico, G. Natile, Einar Sletten

2000

Antitumor Trans Platinum Adducts of GMP and AMP

Yang-Zhong Liu, M. Sivo, G. Natile, E. Sletten

Metal-Based Drugs

1999

Syntheses and Spectral Study of the Solid Complexes of DIPP Ala With Cu(II), Co(II) and Ni(II)

Yang-Zhong Liu

1998

Copper(II), Cobait(II) and Nickel(II) Complexes of N-(O,O-Diisopropyl, Phosph0Ryl)Alanine

Yang-Zhong Liu, Qing-Liang Liu, Guangtao Zhang, Zudc Zhang, Hua-Ming Yu, Ying-Yann Wu

Bioengineering nanomaterials for tumor therapy and anti-metastasis

Junjie Cheng, Yuanbo Pan, Jian-Hua Zou, Miya Zhang, Yang Zhu, Yang-Zhong Liu, Xiaoyuan Chen

Progress in Materials Science

会议论文

2021

纳米抗体介导的肿瘤靶向磁共振成像

刘扬中

《中国稀土学会2021学术年会》

2019

蛋白质与金属药物作用机理

刘扬中

《第十一届全国化学生物学学术会议论文摘要(第一卷)》

2019

NAMI-A Preferentially Reacts with Sp1 protein:Understanding Anti-metastasis Effect of the Drug

Siming Yuan, Siming Chen, Han Wu, Huan Jiang, Shihui Zheng, Yangzhong Liu

《第十一届全国化学生物学学术会议论文摘要(第三卷)》

2019

Protein Reactions in the Mechanism of Metallodrugs

Yangzhong Liu

《中国化学会第六届全国生物物理化学会议(NCBPC-6)摘要集》

2018

靶向砷化合物与环指蛋白/锌指蛋白相互作用的质谱研究

侯壮豪,曹开明,刘扬中,黄光明

《2018年中国质谱学术大会(CMSC 2018)论文集》

2018

基于纳米抗体的金属药物靶向运输

刘扬中

《中国化学会第十四届全国生物无机化学学术会议》

2018

三氧化二砷优先结合环指蛋白PML

曹开明,盛亚平,袁斯明,刘扬中

《中国化学会第十四届全国生物无机化学学术会议》

2018

Sp1感应铜的分子机理研究

袁斯明,陈思明,郗照勇,刘扬中

《中国化学会第十四届全国生物无机化学学术会议》

2018

反式维甲酸铂的合成及抗肿瘤转移活性研究

戴一,黄海,刘扬中

《中国化学会第十四届全国生物无机化学学术会议》

2018

ATPases金属结合域与顺铂反应的差异及铜铂共区域化

房田田,田瑶,袁斯明,Fabio Arnesano,Giovanni Natile,刘扬中

《中国化学会第五届全国生物物理化学会议(NCBPC5)摘要集》

2018

Platinum Anticancer Drugs:from Mechanistic Study to Drug Design

刘扬中

《中国化学会第五届全国生物物理化学会议(NCBPC5)摘要集》

2018

Visualizing Inhibition of the MDM2/p53 Interaction Using Co-expressed Protein Complex

杨洋,Zhiqiang Dong,Hongze Hu,Yangzhong Liu

《中国化学会第五届全国生物物理化学会议(NCBPC5)摘要集》

2017

铂类抗癌药物的机理研究与药物设计

袁斯明,赵林泓,陈思明,郗照勇,师红东,程芹芹,闵元增,刘扬中

《第十届全国化学生物学学术会议报告摘要集》

2016

阿司匹林铂的作用机制与口服药物运输

刘扬中

《中国化学会第30届学术年会摘要集-第七分会:无机化学前沿》

2014

蛋白质在铂类抗肿瘤机理中的作用

赵林泓,陈思明,郗照勇,刘扬中

《中国化学会第29届学术年会摘要集——第22分会:化学生物学》

2014

核磁共振研究蛋白质在铂类抗肿瘤药物中的作用机理

刘扬中

《中国化学会第三届全国生物物理化学会议暨国际华人生物物理化学发展论坛》

2013

Proteins in the Mechanism of Platinum Antitumor Drugs

Yangzhong Liu

《2013第六届国际蛋白质和多肽大会》

2012

核磁共振在金属蛋白与金属药物研究中的应用

刘扬中

《中国化学会成立80周年中国化学会第二届全国生物物理化学会议(NCBPC2)暨国际华人生物物理化学发展论坛会议论文集》

2012

通过纳米载药体系克服顺铂耐药性

闵元增,刘扬中

《中国化学会第28届学术年会第8分会场摘要集》

2011

非经典铂类抗肿瘤药物的机理研究

闵元增,李婵,马国林,许德晨,刘扬中

《2011南湖学术论坛——生物无机化学专题研讨会》

2010

核磁共振研究蛋白质内含子的溶液结构与性质

郑玉船,刘扬中

《第一届全国生物物理化学会议暨生物物理化学发展战略研讨会》

2010

蛋白质内含子—结核杆菌的新药物靶点及其抑制作用

刘扬中

《中华医学会结核病学分会2010年学术年会论文汇编》

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