张永红｜重庆医科大学｜学者主页

2026

哈巴俄苷缓解乙醇合并高糖暴露加剧的胰岛细胞瘤细胞焦亡

符香香，张悦，李晓晗，张宇，项沁，谭力铭，唐槐英，张雍丽，张永红，王启斌，郑涛，陈黎

《中国中药杂志》

2026

Enantioselective Toxicity of Ethiprole to Honeybees (Apis mellifera) via Varying Interference of Cytochrome P450s in Metabolism.

Yonghong Zhang, Zi-Yu Chen, Bao-Hui Wu, Jing-Liang Shi, Xiao-Bo Wu

Journal of Agricultural and Food Chemistry

DOI

2025

miR-100-5p在甲状腺癌细胞中增殖、侵袭和迁移的影响及其靶基因生物信息学预测研究

李天，李永平，萨茹拉，杨成燕，张永红

《牡丹江医科大学学报》

DOI

2025

The interaction and response of gut microbes to exposure to chiral ethiprole in honeybees (Apis mellifera).

Yonghong Zhang, Jian-Hui Liu, Jing-Liang Shi, Bao-Hui Wu, Ze-Tian He, Xiao-Bo Wu

Journal of Hazardous Materials

DOI

2025

Larval antibiotic exposure causes persistent impacts on honeybees across life stages via metabolic succession.

Jing-Liang Shi, Yonghong Zhang, Jian-Hui Liu, Min Xu, Xiao-Bo Wu

Journal of Hazardous Materials

DOI

2025

A Multi-input Deep Learning Architecture for STAT3 Inhibitor Prediction

Kairui Liang, Wenling Qin, Yonghong Zhang

ACS Omega

DOI

2025

A multi-dimensional computational framework of drug-induced hepatotoxicity: integrating molecular structure features with disease pathogenesis

Huayu Zhong, Juanji Wang, Xiaoxiao Liu, Xiaoyun Wei, Chengcheng Zhou, Taiyan Zou, Xin Han, Lingyun Mo, Wenling Qin, Yonghong Zhang

Briefings in Bioinformatics

DOI

2025

Computational Insights Into the Inhibition of Novel Imidazole [1,2‐α] Pyrimidine Derivatives Against Influenza A Virus

Rong Liu, Hongping Wan, Liang Zou, Xingyu Liu, Weichen Yang, Yonghong Zhang, Mao Shu

ChemistrySelect

DOI

2024

Early larval exposure to flumethrin induces long-term impacts on survival and memory behaviors of adult worker bees Apis mellifera.

Jing-Liang Shi, Chen Liu, Yonghong Zhang, Xiao-Bo Wu

Pesticide Biochemistry and Physiology

DOI

2024

Flumethrin exposure perturbs gut microbiota structure and intestinal metabolism in honeybees (Apis mellifera).

Jian-Hui Liu, Jing-Liang Shi, Yueyang Hu, Yuchen Su, Yonghong Zhang, Xiao-Bo Wu

Journal of Hazardous Materials

DOI

2024

Drug repurposing to tackle parainfluenza 3 based on multi-similarities and network proximity analysis

Xinyue Chen, Bo Zhou, Xinyi Jiang, Huayu Zhong, Aijing You, Taiyan Zou, Chengcheng Zhou, Xiaoxiao Liu, Yonghong Zhang

Frontiers in Pharmacology

DOI

2024

Evodiamine inhibits growth of vemurafenib drug-resistant melanoma via suppressing IRS4/PI3K/AKT signaling pathway

Xingxian Guo, Shiying Huang, Yonghong Zhang, Hong Wang, Lisha Li, Jianhua Ran, Dilong Chen, Xiaopeng Li, Jing Li

Journal of Natural Medicines

DOI

2023

Exploring the Hepatotoxicity of Drugs through Machine Learning and Network Toxicological Methods

Tiantian Tang, Xiaofeng Gan, Li Zhou, Kexue Pu, Hong Wang, Weina Dai, Bo Zhou, Lingyun Mo, Yonghong Zhang

Current Bioinformatics

DOI

2022

网络毒理方法用于抗生素肝毒性预测的研究

唐甜甜，张永红

《国外医药(抗生素分册)》

2022

基于网络药理学联合16S rDNA高通量测序技术分析丹参对感染大肠杆菌小鼠肠道菌群的影响

王乐，陈泓岑，张永红，吴琼，侯佳佳，王天祎，卢天航，黄传发，张华，崔德凤

《畜牧兽医学报》

2021

基于Discovery Studio软件的专业学位CADD研究生课程教学案例设计――抗新冠肺炎中药有效成分山奈酚与靶蛋白的分子对接

张永红，蒋启华，李艳

《实用中医药杂志》

2021

Identification of potential therapeutic targets and mechanisms of COVID-19 through network analysis and screening of chemicals and herbal ingredients

Hong Wang, Jingqing Zhang, Zhigang Lu, Weina Dai, Chuanjiang Ma, Yun Xiang, Yonghong Zhang

Briefings in Bioinformatics

DOI

2020

Prediction of Blood-Brain Barrier Permeability of Compounds by Fusing Resampling Strategies and eXtreme Gradient Boosting

Zhiwen Shi, Yanyi Chu, Yonghong Zhang, Yanjing Wang, Dong‐Qing Wei

IEEE Access

DOI

2020

Probing the Mechanism of Hepatotoxicity of Hexabromocyclododecanes through Toxicological Network Analysis

Weina Dai, Tiantian Tang, Zhenghua Dai, Da Shi, Lingyun Mo, Yonghong Zhang

Environmental Science & Technology

DOI

2020

Molecular dynamics simulation and binding free energy calculations of microcin J25 binding to the FhuA receptor

Zhenhua Li, Sathishkumar Chinnasamy, Yonghong Zhang, Dong‐Qing Wei

Journal of Biomolecular Structure and Dynamics

DOI

2019

胃癌化疗抵抗基因PMP22下游的生物信息学机制

汪圣毅，张永红，闫亚飞，李旭升，程彦，李永翔

《安徽医科大学学报》

2019

Computational insight into the conformational transition of human toll-like receptor 8 in the agonist-induced activation processes

Shuheng Huang, Mei Ying Hu, Linxin Chen, Tingting Shi, Zuyin Kuang, Yu Heng, Yonghong Zhang, Laichun Lu

Journal of Biomolecular Structure and Dynamics

DOI

2019

Population Scale Retrospective Analysis Reveals Potential Risk of Cholestasis in Pregnant Women Taking Omeprazole, Lansoprazole, and Amoxicillin

Yonghong Zhang, Da Shi, Ruben A Abagyan, Weina Dai, Mingyang Dong

Interdisciplinary Sciences Computational Life Sciences

DOI

2017

Theoretical Studies of Intracellular Concentration of Micro-organisms’ Metabolites

Hai-Feng Yang, Xiaonan Zhang, Yan Li, Yonghong Zhang, Qin Xu, Dong‐Qing Wei

Scientific Reports

DOI

2017

Comprehensive Interactions of ACE Inhibitors With Their Receptor by a Support Vector Machine Model and Molecular Docking

Ya’nan Liang, Dongya Qin, Yonghong Zhang, Wanqian Liu, Guizhao Liang

Journal of the Chinese Chemical Society

DOI

2016

溴吡斯的明磷脂复合物纳米乳的制备及体内外评价

陈学梁，袁誉铭，张永红，孙全，张景勍

《中国药学杂志》

2016

Recent progresses of simulations on passive membrane permeations in China

Huiyuan Zhang, Qin Xu, Fang Li, Pei-Chuan Tian, Ying-Hao Wang, Yi Xiong, Yonghong Zhang, Dong‐Qing Wei

Molecular Simulation

DOI

2015

Destabilization of Alzheimer’s Aβ42 Protofibrils with a Novel Drug Candidate wgx-50 by Molecular Dynamics Simulations

Huai‐Meng Fan, Ruo‐Xu Gu, Yanjing Wang, Yun-Long Pi, Yonghong Zhang, Qin Xu, Dong‐Qing Wei

The Journal of Physical Chemistry B

DOI

2015

Prediction of Placental Barrier Permeability: A Model Based on Partial Least Squares Variable Selection Procedure

Yonghong Zhang, Zhining Xia, Yan Li, Shu‐Shen Liu

Molecules

DOI

2015

Improved feature-based prediction of SNPs in human cytochrome P450 enzymes

Li Li, Yi Xiong, Zhuoyu Zhang, Quan Guo, Qin Xu, Hien-haw Liow, Yonghong Zhang, Dong‐Qing Wei

Interdisciplinary Sciences Computational Life Sciences

DOI

2014

脱甲氧基姜黄素磷脂复合物药代动力学研究

罗见春，胡雪原，王红，张永红，张景勍

《中药材》

DOI

2013

基于PLS变量筛选法的QSAR模型快速评价药物的ADME活性

张永红

《重庆大学》

2011

PLS变量筛选法用于有机物透聚乙烯膜性能QSAR研究

张永红，刘树深，肖乾芬，覃礼堂，夏之宁

《化学学报》

2010

Prediction of blood–brain partitioning: A model based on molecular electronegativity distance vector descriptors

Yonghong Zhang, Zhining Xia, Li‐Tang Qin, Shu‐Shen Liu

Journal of Molecular Graphics and Modelling

DOI

2009

Support vector regression and least squares support vector regression for hormetic dose–response curves fitting

Li‐Tang Qin, Shu‐Shen Liu, Hailing Liu, Yonghong Zhang

Chemosphere

DOI

1999

Effects of aluminum 3-oxo-acetyl-11-deoxoglycyrrhetinate on gastric ulcers in rats

杨锦南，朱明，张玉林，曹中亮，刘春霞，王素琴，王彩兰，张永红

《中国药理学与毒理学杂志》

精选作品

期刊论文

哈巴俄苷缓解乙醇合并高糖暴露加剧的胰岛细胞瘤细胞焦亡

Enantioselective Toxicity of Ethiprole to Honeybees (Apis mellifera) via Varying Interference of Cytochrome P450s in Metabolism.

miR-100-5p在甲状腺癌细胞中增殖、侵袭和迁移的影响及其靶基因生物信息学预测研究

The interaction and response of gut microbes to exposure to chiral ethiprole in honeybees (Apis mellifera).

Larval antibiotic exposure causes persistent impacts on honeybees across life stages via metabolic succession.

A Multi-input Deep Learning Architecture for STAT3 Inhibitor Prediction

A multi-dimensional computational framework of drug-induced hepatotoxicity: integrating molecular structure features with disease pathogenesis

Computational Insights Into the Inhibition of Novel Imidazole [1,2‐α] Pyrimidine Derivatives Against Influenza A Virus

Early larval exposure to flumethrin induces long-term impacts on survival and memory behaviors of adult worker bees Apis mellifera.

Flumethrin exposure perturbs gut microbiota structure and intestinal metabolism in honeybees (Apis mellifera).

Drug repurposing to tackle parainfluenza 3 based on multi-similarities and network proximity analysis

Evodiamine inhibits growth of vemurafenib drug-resistant melanoma via suppressing IRS4/PI3K/AKT signaling pathway

Exploring the Hepatotoxicity of Drugs through Machine Learning and Network Toxicological Methods

网络毒理方法用于抗生素肝毒性预测的研究

基于网络药理学联合16S rDNA高通量测序技术分析丹参对感染大肠杆菌小鼠肠道菌群的影响

基于Discovery Studio软件的专业学位CADD研究生课程教学案例设计――抗新冠肺炎中药有效成分山奈酚与靶蛋白的分子对接

Identification of potential therapeutic targets and mechanisms of COVID-19 through network analysis and screening of chemicals and herbal ingredients

Prediction of Blood-Brain Barrier Permeability of Compounds by Fusing Resampling Strategies and eXtreme Gradient Boosting

Probing the Mechanism of Hepatotoxicity of Hexabromocyclododecanes through Toxicological Network Analysis

Molecular dynamics simulation and binding free energy calculations of microcin J25 binding to the FhuA receptor

胃癌化疗抵抗基因PMP22下游的生物信息学机制

Computational insight into the conformational transition of human toll-like receptor 8 in the agonist-induced activation processes

Population Scale Retrospective Analysis Reveals Potential Risk of Cholestasis in Pregnant Women Taking Omeprazole, Lansoprazole, and Amoxicillin

Theoretical Studies of Intracellular Concentration of Micro-organisms’ Metabolites

Comprehensive Interactions of ACE Inhibitors With Their Receptor by a Support Vector Machine Model and Molecular Docking

溴吡斯的明磷脂复合物纳米乳的制备及体内外评价

Recent progresses of simulations on passive membrane permeations in China

Destabilization of Alzheimer’s Aβ42 Protofibrils with a Novel Drug Candidate wgx-50 by Molecular Dynamics Simulations

Prediction of Placental Barrier Permeability: A Model Based on Partial Least Squares Variable Selection Procedure

Improved feature-based prediction of SNPs in human cytochrome P450 enzymes

脱甲氧基姜黄素磷脂复合物药代动力学研究

基于PLS变量筛选法的QSAR模型快速评价药物的ADME活性

PLS变量筛选法用于有机物透聚乙烯膜性能QSAR研究

Prediction of blood–brain partitioning: A model based on molecular electronegativity distance vector descriptors

Support vector regression and least squares support vector regression for hormetic dose–response curves fitting

Effects of aluminum 3-oxo-acetyl-11-deoxoglycyrrhetinate on gastric ulcers in rats

会议论文

阿奇霉素泡囊在小鼠体内的组织分布研究

研究方向