百晓学者学者目录

赵宾宾

副教授、教授、讲师，湖北中医药大学

精选作品

期刊论文

2026

基于CiteSpace的中医药防治阿尔茨海默病热点与趋势分析

王吉林，林怡，刘芳，李蓉，石和元，刘爽，吴永贵，赵宾宾

《时珍国医国药》

2026

通脉降糖胶囊防治糖尿病认知障碍的作用及机制研究

刘芳，刘怡，赵梦，吴微，林怡，吴永贵，郭淑允，杨琼，赵宾宾

《时珍国医国药》

2026

开心散及其组方成分干预糖脂代谢研究

钟志艳，王晓瑞，刘琳，沈宇声，赵宾宾，孔明望

《中华中医药学刊》

2026

Systematic Proteomic Characterization of EV‐A71‐Infected Mice Identifies Dynamic Molecular Changes and Therapeutic Targets

Wanjun Peng, Qiao-Chu Wang, Binbin Zhao, Lihong Zhang, Jing Wu, Xiaohui Wei, Na Rong, Zhaohua Wang, Kaihui Liu, Jiang-Feng Liu, Jun-Tao Yang, Jiang-Ning Liu

MedComm

DOI

2026

Characterization of Bronchiolitis and Vaccine-induced Enhanced Respiratory Disease in Syrian Hamsters Caused by Respiratory Syncytial Virus Infection

Binbin Zhao, Geng-Xin Zhang, Jing Wu, Wei Zhang, Xiaoyue Ding, Xiaohui Wei, Wanjun Peng, Na Rong, Hekai Yang, Jiang-Ning Liu

Journal of Infectious Diseases

DOI

2026

From weak but broad to potent and universal: A trispecific antibody against conserved SARS-CoV-2 spike epitopes.

Xiao Tian, Chunmei Wang, Pu Han, Hong-Hui Liu, Lili Wu, Xiaoyu Wang, Shu-rong Yu, Yanning Zhang, Binbin Zhao, Jiang-Ning Liu, G. Gao, Qihui Wang

Molecular Therapy

DOI

2026

Comparative virology and pathology of Monkeypox virus in Syrian hamsters, C57BL/6, and BALB/c mice: A framework for preclinical model selection

Xiaohui Wei, Jing Wu, Hekai Yang, Na Li, Binbin Zhao, Wanjun Peng, Na Rong, Wei Zhang, Jing Xue, Jiang-Ning Liu

Animal Models and Experimental Medicine

DOI

2026

Tryptophan metabolism in neonicotinoids exposure-induced diabetes: Emerging insights and predictive implications

Beini Li, Qiong Yang, Yong Hui Yu, Yao Chen, Mengfei Xu, Fang Liu, Xuerong Chen, Wenwen Yang, Xuemei Wang, Daqing Yang, Song Shi, Shuang Zhou, Binbin Zhao, Wei Wu

Ecotoxicology and Environmental Safety

DOI

2025

六味地黄丸减轻MSG-肝再生大鼠模型眶额叶皮层神经炎症损伤的机制研究

吴稀挺，杨杰，赵子浩，王吉林，李蓉，赵宾宾

《中西医结合肝病杂志》

2025

基于网络药理学和实验验证探讨藤茶-青钱柳对预防急性酒精中毒的作用机制

王晓瑞，李莹，王莹，刘琳，俞琦，赵宾宾，孔明望

《海南医科大学学报》

2025

中医体质学在老年脑健康中的应用价值与应用路径思考

李蓉，吴永贵，杨琼，王吉林，李馨，张俊英，赵宾宾

《时珍国医国药》

2025

Immune imprinting blunts omicron pathogenicity fluctuations and highlights the essential role of cellular immunity in SARS-CoV-2 infection.

Xiaohui Wei, Hekai Yang, Jing Wu, Binbin Zhao, Y. Mu, Na Rong, Geng-Xin Zhang, Wanjun Peng, Lihong Zhang, Wei Zhang, Xiaoyue Ding, Gao-Ying Zhang, Zhi-Hai Chen, Jiang-Ning Liu

Cell Reports

DOI

2025

Structural conservation and functional adaptation of porcine interleukin-10: evolutionary insights and viral mimicry.

Xiaohui Wei, Jing Wu, Su-Qiu Wang, Hekai Yang, Binbin Zhao, Na Rong, Wei Zhang, Jiang-Ning Liu

International Journal of Biological Macromolecules

DOI

2025

Single-cell transcriptomic atlas of blood and lung from mice infected with SARS-CoV-2 revealing distinct virulence characteristics between prototype and Omicron BA.1 strain

Na Rong, Jiaying Yao, Hui Quan, Jing Wu, Binbin Zhao, Wanjun Peng, Hekai Yang, Geng-Xin Zhang, Xiaoyue Ding, Xiaohui Wei, Jiang-Ning Liu

Virulence

DOI

2025

Dynamic Molecular Changes in Brain, Lung, and Heart of Hamsters Infected With SARS‐CoV‐2: Insights From a Severe and Recovery Phase Model

Wanjun Peng, Xiaohui Wei, Yue Wu, Chun-Mei Shi, Xiao-Yan Liu, Jing Wu, Hekai Yang, Na Rong, Binbin Zhao, Geng-Xin Zhang, Wei Zhang, Jiang-Feng Liu, Jiang-Ning Liu, Jun-Tao Yang

Journal of Medical Virology

DOI

2025

Enantiomer-dependent and modification-free DNA matrix as an adjuvant for subunit vaccines against SARS-CoV-2 or pneumococcal infections

Cui-Feng Li, Yuxin Li, Bini Zhou, Tong Li, Xiaohui Wei, Kun Chen, Wenlong Chen, Zi-Wei Shi, X. Dai, Jiachen Zhang, Chen Yang, Zhenglin Ji, Wen-Bo Sun, Ji Gao, Jing Wu, Binbin Zhao, Xin Min, Yujie Li, Lin Lin, Wei Yang, Min Wang, Ze-Zhong Liu, Yaping Liu, Chenyou Zhu, Bo Yang, Jiang-Fei Xu, Li-Tang Yan, Yi Shi, Lu Lu, Lin-Qi Zhang, Qiang Ding, Jing Xue, Bai-Dong Hou, Hai Qi, Jiang-Ning Liu, Y. Yang, Dong-Sheng Liu, Wan-Li Liu

Nature Biomedical Engineering

DOI

2025

Structural characterization and immunomodulatory activity of polysaccharides from the roots of Artemisia argyi

Gai-Fan Ma, Bin-Bin Zhao, Peili Tang, Daizhi Tian, Yi Zhao, Zenggen Liu, Linlin Chen

Carbohydrate Polymers

DOI

2025

Dietary Quercetin Intake Is Associated With a Lower Risk of Diabetic Nephropathy in US Adults: Data From NHANES 2007–2008, 2009–2010, and 2017–2018

Fang Liu, Binbin Zhao, Wei Hua Wu, Fang Yang, M L Deng, Suqing Wang

Food Science & Nutrition

DOI

2024

Gut microbiota dysbiosis promotes cognitive impairment via bile acid metabolism in major depressive disorder

Min Jia, Yajuan Fan, Qingyan Ma, Ding Yang, Yunpeng Wang, Xiaoyan He, Binbin Zhao, Xianyan Zhan, Zhiyang Qi, Yifan Ren, Ziqing Dong, Feng Zhu, Wei Wang, Yuan Gao, Xiancang Ma

Translational Psychiatry，Vol. 14, No. 10

DOI

2024

基于p38 MAPK信号通路探讨生慧颗粒对AD模型大鼠EC与CA1区影响及作用机制

李泽飞，赵宾宾，石和元，王平

《世界科学技术-中医药现代化》

2024

基于网状Meta分析评价经典名方治疗痴呆的疗效与安全性

俞琦，张济显，石和元，赵宾宾，孔明望

《海南医科大学学报》

2024

Cepharanthine analogs mining and genomes of Stephania accelerate anti-coronavirus drug discovery

L. Leng, Zhi-Chao Xu, B. Hong, Binbin Zhao, Ya Tian, Can Wang, Lulu Yang, Zhongmei Zou, Lingyu Li, Ke Liu, Wanjun Peng, Jiang-Ning Liu, Zhoujie An, Yalin Wang, Bao-Zhong Duan, Zhi-Cheng Hu, Chuan Zheng, Sanyin Zhang, Xiao-Die Li, Mao-Chen Li, Zhao-Yu Liu, Zenghao Bi, Tianxing He, Baimei Liu, Hua-Ying Fan, Chi Song, Yi-Gang Tong, Shi-Lin Chen

Nature Communications

DOI

2024

The Development of Animal Models for Respiratory Syncytial Virus (RSV) Infection and Enhanced RSV Disease

Geng-Xin Zhang, Binbin Zhao, Jiang-Ning Liu

Viruses

DOI

2024

The Milk of Cows Immunized with Trivalent Inactivated Vaccines Provides Broad-Spectrum Passive Protection against Hand, Foot, and Mouth Disease in Neonatal Mice

Xiaohui Wei, Jing Wu, Wanjun Peng, Xin Chen, Lihong Zhang, Na Rong, Hekai Yang, Geng-Xin Zhang, Gao-Ying Zhang, Binbin Zhao, Jiang-Ning Liu

Vaccines

DOI

2024

Pathogenicity and landscape of differential gene expression in mice orally infected with clinical coxsackievirus A6 (CA6)

Lihong Zhang, Wanjun Peng, Jing Wu, Xiaohui Wei, Na Rong, Geng-Xin Zhang, Hekai Yang, Xiaoyue Ding, Binbin Zhao, Jiang-Ning Liu

Journal of Virology

DOI

2024

Comparison of the pathogenicity and neutrophil and monocyte response between SARS‐CoV‐2 prototype and Omicron BA.1 in a lethal mouse model

Na Rong, Jing Wu, Binbin Zhao, Wanjun Peng, Hekai Yang, Geng-Xin Zhang, Da Ruan, Xiaohui Wei, Jiang-Ning Liu

Animal Models and Experimental Medicine

DOI

2024

Pathogenicity and transcriptomic profiling reveals immunology molecular hallmarks after CA10 virus infection

Wanjun Peng, Jing Wu, Binbin Zhao, Lihong Zhang, Xin Chen, Xiaohui Wei, Na Rong, Yun-Lin Han, Jiang-Ning Liu

Animal Models and Experimental Medicine

DOI

2023

SuanZaoRen decoction alleviates neuronal loss, synaptic damage and ferroptosis of AD via activating DJ-1/Nrf2 signaling pathway

Qinghua Long, Tong Li, Qihang Zhu, Liling He, Bin-Bin Zhao

Journal of Ethnopharmacology

DOI

2023

The chemical composition of Diwu YangGan capsule and its potential inhibitory roles on hepatocellular carcinoma by microarray-based transcriptomics

Qingxin Shi, Jiangcheng He, Guangya Chen, Jinlin Xu, Zhaoxiang Zeng, Xueyan Zhao, Bin-Bin Zhao, Xiang Gao, Zhihua Ye, Mingzhong Xiao, Hanmin Li

Journal of Traditional and Complementary Medicine

DOI

2023

Structural characterization and immunomodulatory activity of a novel polysaccharide from Panax notoginseng

Xue‐Lian Jiang, Gai-Fan Ma, Bin-Bin Zhao, Yan Meng, Lin-Lin Chen

Frontiers in Pharmacology

DOI

2023

Distinct astrocytic modulatory roles in sensory transmission during sleep, wakefulness, and arousal states in freely moving mice

Fushun Wang, Wei Wang, Simeng Gu, Dan Qi, Nathan Smith, Weiguo Peng, Wei Dong, Jiajin Yuan, Bin-Bin Zhao, Ying Qing Mao, Peng Cao, Qing Richard Lu, Lee A. Shapiro, S. Stephen Yi, Erxi Wu, Jason Haitao Huang

Nature Communications

DOI

2022

Characterizing serum amino acids in schizophrenic patients: Correlations with gut microbes

Wei Wang, Yunpeng Wang, Qingyan Ma, Fengjie Gao, Lina Zhou, Yajuan Fan, Binbin Zhao, Wenyu Xi, Chuyao Wang, Feng Zhu, Xiancang Ma

Journal Of Psychiatric Research，Vol. 153

DOI

2022

Sleep Efficiency May Predict Depression in a Large Population-Based Study

Bin Yan, Binbin Zhao, Xiaoying Jin, Wenyu Xi, Jian Yang, Lihong Yang, Xiancang Ma

Frontiers In Psychiatry，Vol. 13

DOI

2022

Stressful events induce long-term gut microbiota dysbiosis and associated post-traumatic stress symptoms in healthcare workers fighting against COVID-

Fengjie Gao, Ruijin Guo, Qingyan Ma, Yening Li, Wei Wang, Yajuan Fan, Yanmei Ju, Binbin Zhao, Yuan Gao, Li Qian, Zai Yang, Xiaoyan He, Xiaoying Jin, Yixin Liu, Yuan Peng, Ce Chen, Yunchun Chen, Chengge Gao, Feng Zhu, Xiancang Ma

Journal Of Affective Disorders，Vol. 303

DOI

2022

Systems biological assessment of altered cytokine responses to bacteria and fungi reveals impaired immune functionality in schizophrenia

Yuan Gao, Yajuan Fan, Zai Yang, Qingyan Ma, Binbin Zhao, Xiaoyan He, Fengjie Gao, Li Qian, Wei Wang, Ce Chen, Yunchun Chen, Chengge Gao, Xiancang Ma, Feng Zhu

Molecular Psychiatry，Vol. 270, No. 20

DOI

2022

Mendelian randomization analyses reveal novel drug targets for anorexia nervosa

Jian Yang, Yajuan Fan, Bin Yan, Binbin Zhao, Li Qian, Fengjie Gao, Qingyan Ma, Lihong Yang, Wei Wang, Ling Bai, Feng Zhu, Xiancang Ma

Progress In Neuro-Psychopharmacology & Biological Psychiatry，Vol. 112

DOI

2022

生慧汤对APP/PS1双转基因痴呆小鼠海马JAK2/STAT3/SOCS-1信号通路的影响

龙清华，赵宾宾，丁莉，王平

《中国中西医结合杂志》

2022

A potent, broadly protective vaccine against SARS-CoV-2 variants of concern

Zi-Yan Wang, Jiao An, Kun-Peng Liu, Pin Yu, Xin Fang, Jiadai Li, Hua-Song Zhu, Qianjun Zhu, Chuanqi Huang, Chao Zhang, Binbin Zhao, L. Bao, Yu-Jiao Song, Xi-chuan Cao, Dongdong Hu, Yuanxiang Jiang, Li-Kang Shi, Lingyun Zhou, Jiang Fan, W. Guan, Chenliang Zhou, Zhongyu Hu, Zhiming Yuan, Jiang-Ning Liu, Shan Chao, Ge Liu

npj Vaccines

DOI

2021

Genetically Determined Levels of Serum Metabolites and Risk of Neuroticism: A Mendelian Randomization Study

Li Qian, Yajuan Fan, Fengjie Gao, Binbin Zhao, Bin Yan, Wei Wang, Jian Yang, Xiancang Ma

International Journal Of Neuropsychopharmacology，Vol. 24, No. 1

DOI

2021

酸枣仁汤通过抑制神经炎症和改善神经营养水平促进APP/PS1痴呆小鼠海马神经发生

龙清华，赵宾宾，丁莉，谭爱华，王平

《世界科学技术-中医药现代化》

2021

SARS-CoV-2 Causes a Systemically Multiple Organs Damages and Dissemination in Hamsters

Zhi-Qi Song, L. Bao, Pin Yu, Fei-Fei Qi, Shuran Gong, Jie Wang, Binbin Zhao, Ming-Ya Liu, Yun-Lin Han, Wei Deng, Jiang-Ning Liu, Q. Wei, Jing Xue, Wen-Jie Zhao, C. Qin

Frontiers in Microbiology

DOI

2021

Susceptibility and Attenuated Transmissibility of SARS-CoV-2 in Domestic Cats

L. Bao, Zhi-Qi Song, Jing Xue, Hong Gao, Jiang-Ning Liu, Jie Wang, Qian Guo, Binbin Zhao, Ya-Jin Qu, Fei-Fei Qi, Shuran Gong, Ming-Ya Liu, Qi Lv, Dan Li, Yun-Lin Han, Wen-Jie Zhao, Shou-Long Deng, Yunpeng Liu, Zhi-Guang Xiang, Bochao Yang, Wei Deng, Hai-Sheng Yu, Z. Cong, Q. Wei, Jian-Guo Xu, G. Gao, C. Qin

Journal of Infectious Diseases

DOI

2021

Sequential infection with H1N1 and SARS-CoV-2 aggravated COVID-19 pathogenesis in a mammalian model, and co-vaccination as an effective method of prevention of COVID-19 and influenza

L. Bao, Wei Deng, Fei-Fei Qi, Qi Lv, Zhi-Qi Song, Jiang-Ning Liu, Hong Gao, Q. Wei, Pin Yu, Yan-Feng Xu, Ya-Jin Qu, Feng-Di Li, Jing Xue, Shuran Gong, Ming-Ya Liu, Guanpeng Wang, Shun-Yi Wang, Binbin Zhao, Bin Cong, Chuan Qin

Signal Transduction and Targeted Therapy

DOI

2020

Transplantation of microbiota from drug-free patients with schizophrenia causes schizophrenia-like abnormal behaviors and dysregulated kynurenine metabolism in mice

Feng Zhu, Ruijin Guo, Wei Wang, Yanmei Ju, Qi Wang, Qingyan Ma, Qiang Sun, Yajuan Fan, Yuying Xie, Zai Yang, Zhuye Jie, Binbin Zhao, Liang Xiao, Lin Yang, Tao Zhang, Bing Liu, Liyang Guo, Xiaoyan He, Yunchun Chen, Ce Chen, Chengge Gao, Xun Xu, Huanming Yang, Jian Wang, Yonghui Dang, Lise Madsen, Susanne Brix, Karsten Kristiansen, Huijue Jia, Xiancang Ma

Molecular Psychiatry，Vol. 250, No. 110

DOI

2020

Assessing the Causal Effects of Human Serum Metabolites on 5 Major Psychiatric Disorders

Jian Yang, Bin Yan, Binbin Zhao, Yajuan Fan, Xiaoyan He, Lihong Yang, Qingyan Ma, Jie Zheng, Wei Wang, Ling Bai, Feng Zhu, Xiancang Ma

Schizophrenia Bulletin，Vol. 460, No. 40

DOI

2020

Immunization with a fusion protein vaccine candidate generated from truncated peptides of human enterovirus 71 protects mice from lethal enterovirus 71 infections

Jiang-Ning Liu, Binbin Zhao, Ling Xue, Jing Wu, Yan-Feng Xu, Yongdong Liu, C. Qin

Virology Journal

DOI

2019

Identification of schizophrenia related biological pathways across eight brain regions

Jian Yang, Bin Yan, Yajuan Fan, Lihong Yang, Binbin Zhao, Feng Zhu, Jie Zheng, Wei Wang, Ling Bai, Feng Zhang, Xiancang Ma

Behavioural Brain Research，Vol. 360

DOI

2019

三草安神方对抑郁症失眠大鼠海马凋亡相关蛋白表达的调节作用

龙清华，赵宾宾，徐波，王平

《中华中医药杂志》

2019

柴胡疏肝散对MSG-大鼠-肝再生模型眶额叶皮层损伤的保护作用

赵宾宾，龙清华，王平，李瀚旻

《中华中医药杂志》

2019

中医气虚证评价指标的研究概况

蔡铭，夏婧，郑桃云，赵宾宾，王平

《中华中医药杂志》

2019

酸枣仁汤对慢性睡眠剥夺大鼠海马5-HT1AR和5-HT2AR表达的影响

肖迪，刘俊，赵宾宾

《西部中医药》

2019

酸枣仁汤对慢性睡眠剥夺大鼠视交叉上核生物钟基因Clock和Bmal1表达的影响

张付民，冉仁国，赵宾宾

《湖南中医药大学学报》

2019

电针联合氟西汀片对骨癌痛大鼠抑郁样行为改善作用的研究

覃双来，赵宾宾，关江锋，吴永贵，张秋

《中医药信息》

DOI

2019

Diwu Yanggan Modulates the Wnt/β-catenin Pathway and Inhibits Liver Carcinogenesis Signaling in 2-AAF/PH Model Rats

Bin-Bin Zhao, Zhihua Ye, Xiang Gao, Hanmin Li

Current Medical Science

DOI

2019

Preventive Effects of Escitalopram Against Anxiety-Like Depressive Behaviors in Monosodium Glutamate-Teated Rats Subjected to Partial Hepatectomy

Bin-Bin Zhao, Linlin Chen, Qinghua Long, Guangjing Xie, Bo Xu, Ze-fei Li, Ping Wang, Hanmin Li

Frontiers in Psychology

DOI

2019

Simultaneous determination of phenolic acids and flavonoids in Artemisiae Argyi Folium by HPLC-MS/MS and discovery of antioxidant ingredients based on relevance analysis

Jia-Xuan Xia, Bin-Bin Zhao, Jun-Feng Zan, Ping Wang, Linlin Chen

Journal of Pharmaceutical and Biomedical Analysis

DOI

2018

三草安神方对抑郁症失眠大鼠学习记忆力及神经递质受体表达的影响

龙清华，赵宾宾，王平

《中华中医药杂志》

2018

GS‐9620 inhibits enterovirus 71 replication mainly through the NF‐&kgr;B and PI3K‐AKT signaling pathways

Qian Zhang, Binbin Zhao, Xin Chen, Nan Song, Jing Wu, Guang-Chao Li, Pin Yu, Yun-Lin Han, Jiang-Ning Liu, C. Qin

Antiviral Research

DOI

2018

Diwu Yanggan capsule improving liver histological response for patients with HBeAg-negative chronic hepatitis B: a randomized controlled clinical trial.

Hanmin Li, Zhihua Ye, Xiang Gao, Lisheng Zhang, Xin Yao, Jian-Xun Gu, Dingbo Lu, Ming Wan, Lin Xiao, Wangxi Cai, Xuesheng Yan, Bin-Bin Zhao, Yu Wu, Jinrong Zhang

PubMed

2018

Diwu Yanggan capsule inhibits the occurrence and development of liver cancer in the Solt-Farber rat model by regulating the Ras/Raf/Mek/Erk signaling pathway.

Zhihua Ye, Xiang Gao, Bin-Bin Zhao, Hanmin Li, Ming Wan, Na Wu, Mingxiang Chang, Sisi Cheng

PubMed

2018

Protective Effects of Liu Wei Di Huang Wan on the Liver, Orbitofrontal Cortex Nissl Bodies, and Neurites in MSG+PH‐Induced Liver Regeneration Rat Model

Bin-Bin Zhao, Qinghua Long, Chaoyang Wang, Linlin Chen, Guangjing Xie, Wen-ji Bo, Bo Xu, Ze-fei Li, Hanmin Li, Ping Wang

Evidence-based Complementary and Alternative Medicine

DOI

2015

“补肾生髓成肝”改善肝再生微环境、防治肝癌的作用及机制

李瀚旻，赵宾宾，高翔，沈昕，吴雨，张金荣，宋红丽，叶之华，程思思

《湖北中医药大学学报》

2015

地五养肝胶囊抑制2-AAF/PH大鼠肝癌前病变的作用及机制

赵宾宾

《湖北中医药大学》

2015

The Herbal Compound “Diwu Yanggan” Modulates Liver Regeneration by Affecting the Hepatic Stem Cell Microenvironment in 2-Acetylaminofluorene/Partial Hepatectomy Rats

Bin-Bin Zhao, Hanmin Li, Xiang Gao, Zhihua Ye, Sisi Cheng

Evidence-based Complementary and Alternative Medicine

DOI

2014

“补肾生髓成肝”法联合聚乙二醇干扰素α-2a治疗慢性乙型肝炎的临床研究

兰少波，王建忠，李瀚旻，高翔，叶之华，赵宾宾

《中西医结合肝病杂志》

2013

地五养肝胶囊对肝肾精虚大鼠肝再生的影响

宋红丽，李瀚旻，林立生，高翔，赵宾宾，张军，吴雨，晏雪生，肖玲

《中西医结合肝病杂志》

会议论文

2016

基于圆运动思想试析张梦侬治疗荨麻疹的思路

张翀，赵宾宾，王平

《中华中医药学会第十六次内经学术研讨会论文集》

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