百晓学者学者目录

史宣玲

副研究员、教授，清华大学

精选作品

期刊论文

2026

Broad and durable protection against SARS-CoV-2 and SARS-CoV by an intranasal chimpanzee adenovirus vaccine expressing tandem RBDs and nucleocapsid

Yaping Liu, Run-Hong Zhou, Tian Zhao, Ruoke Wang, Kun Zhu, Jun-Xian Hong, Ziqing Yang, Qian-Qian Yang, Yuqing Lei, Yang Bai, Jing Wei, Peng Chen, Xin-Yu Fan, Qi Zhang, Xuan-Ling Shi, Peng Liu, Zhiwei Chen, Lin-Qi Zhang

PLoS Pathogens

DOI

2026

Twenty-year persistence of SARS-CoV-1 immune imprinting shapes antibody responses to SARS-CoV-2 infection.

Qi Zhang, Peng Chen, Feng-Lin Guo, Run-Hong Zhou, Rui-Han Guo, Xiao-Fei Ge, Qian-Qian Yang, Xin Xie, Wei Xia, Jun-Ping Fan, Ziqing Yang, Yan Xu, Hui-Yu Huang, Jin-Qian Li, Han Wang, Hui-Wen Liao, Xuan-Ling Shi, Na Liu, Yu-Ting Chen, Zhiwei Chen, Jian-Zhu Ma, Xin-Quan Wang, Tong Zhang, Lin-Qi Zhang

Immunity

DOI

2026

Decoding antibody response to MERS-CoV in wild dromedary camels

F. Idoudi, Ruoke Wang, L. Tian, Ziqing Yang, K. Chik, Peng Chen, R. Benabderrazek, L. Fu, Ruijie Tan, Sayda Dhaouadi, Z. Benlasfar, M. Somia, Qi Zhang, Xuan-Ling Shi, Jasper Fuk-Woo Chan, Kwok-Yung Yuen, Xinquan Wang, B. Bouhaouala-Zahar, Lin-Qi Zhang

Proceedings of the National Academy of Sciences of the United States of America

DOI

2026

Identification and characterization of bone marrow plasma cells producing IFN-γ-neutralizing autoantibodies in adult-onset immunodeficiency

Han Wang, Qianqian Yang, Tian Zhao, Jinfang Yu, Yuqing Lei, Y. Yang, Siqi Pan, Xin Wang, Xin Wang, Junxian Hong, Zimeng Wei, Xinyu Fan, Jiaxiang Li, Yaqi Wang, Haodi Dong, Panpan Zhou, Qi Zhang, Xuanling Shi, Jinglan Wang, Xinquan Wang, Xinquan Wang, Peng Liu, Junping Fan, Linqi Zhang

Cell Reports Medicine

DOI

2026

Decoding antibody response to MERS-CoV in wild dromedary camels

Faten Idou, Ruoke Wang, Long Tian, Ziqing Yang, Kenn Ka‐Heng Chik, P Chen, Rahma Benabderra, Lili Fu, Ruijie Tan, Say Dhaouad, Zakaria Benlasfar, Mahmoud Somia, Zh, Qi, Xuanling Shi, Jasper Fuk-Woo, Kwok‐Yung Yuen, Xinquan Wang, Balkiss Bouhaouala‐Zahar, Linqi Zhang

INRIA a CCSD electronic archive server

DOI

2024

Exploring distinct modes of inter-spike cross-linking for enhanced neutralization by SARS-CoV-2 antibodies

Xuanyu Nan, Yu-Jie Li, Rui Zhang, Ruoke Wang, Nian-Nian Lv, Jia-Yi Li, Yuanfang Chen, Bini Zhou, Yangjunqi Wang, Ziyi Wang, Jiayi Zhu, Jing Chen, Jin-Qian Li, Wenlong Chen, Qi Zhang, Xuan-Ling Shi, Changwen Zhao, Chunying Chen, Zhihua Liu, Yu-Liang Zhao, Dong-Sheng Liu, Xin-Quan Wang, Li-Tang Yan, Tai-Sheng Li, Lin-Qi Zhang, Y. Yang

Nature Communications

DOI

2024

CAR-T Therapy in HIV: Pioneering Advances and Navigating Challenges

Xiao Wang, Jianyang Liu, Fei-Ke Hao, Tatchapon Ajavavarakula, Xuan-Ling Shi

Infectious Diseases & Immunity

DOI

2024

Distinct Binding Modes of Inter-Spike Cross-Linking Suggest a Supplementary Mechanism for SARS-CoV-2 Antibody Neutralization

Xuanyu Nan, Yu-Jie Li, Rui Zhang, Ruoke Wang, Nian-Nian Lv, Jia-Yi Li, Yuanfang Chen, Bini Zhou, Yangjunqi Wang, Ziyi Wang, Jiayi Zhu, Jing Chen, Jin-Qian Li, Wenlong Chen, Qi Zhang, Xuan-Ling Shi, Changwen Zhao, Chunying Chen, Zhihua Liu, Yu-Liang Zhao, Dong-Sheng Liu, Xin-Quan Wang, Li-Tang Yan, Tai-Sheng Li, Lin-Qi Zhang, Y. Yang

bioRxiv

DOI

2024

Super broad and protective nanobodies against Sarbecoviruses including SARS-CoV-1 and the divergent SARS-CoV-2 subvariant KP.3.1.1

Haodi Dong, Run-Hong Zhou, Jing Chen, Jing Wei, Zimeng Wei, Ziqing Yang, Kun Zhu, Yufan Yang, Qian-Qian Yang, Na Liu, Yu-Ting Chen, Yu-Han Wu, Yan Liang, Yige Zeng, Qile Guo, Mingxi Li, S. Shan, Han Wang, Mengyue Niu, Isabella Yunfei Zeng, Xuan-Ling Shi, Qi Zhang, Xin-Quan Wang, Zhiwei Chen, Lin-Qi Zhang

PLoS Pathogens

DOI

2024

DS2 designer pre-fusion F vaccine induces strong and protective antibody response against RSV infection

Yiling Yang, Ruoke Wang, Feng-Lin Guo, Tian Zhao, Yuqing Lei, Qian-Qian Yang, Yige Zeng, Ziqing Yang, Tatchapon Ajavavarakula, Ruijie Tan, Mingxi Li, Haodi Dong, Mengyue Niu, Keyan Bao, Hao Geng, Qining Lv, Qi Zhang, Xuan-Ling Shi, Peng Liu, J. Ge, Xin-Quan Wang, Lin-Qi Zhang

npj Vaccines

DOI

2023

Novel TLR7/8 agonists promote activation of HIV-1 latent reservoirs and human T and NK cells

Yangyang Li, Zhisong Wang, Ying Hou, Xiaoyu Liu, Jun-Xian Hong, Xuan-Ling Shi, Xiao-Jie Huang, Tong Zhang, Xuebin Liao, Lin-Qi Zhang

Frontiers in Microbiology

DOI

2023

Dissecting the intricacies of human antibody responses to SARS-CoV-1 and SARS-CoV-2 infection.

Ruoke Wang, Yang Han, Rui Zhang, Jiayi Zhu, Xuanyu Nan, Yaping Liu, Ziqing Yang, Bini Zhou, Jin-Fang Yu, Zichun Lin, Jin-Qian Li, Peng Chen, Yangjunqi Wang, Yujie Li, Dong-Sheng Liu, Xuan-Ling Shi, Xin-Quan Wang, Qi Zhang, Y. Yang, Tai-Sheng Li, Lin-Qi Zhang

Immunity

DOI

2023

Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariants

B. Ju, Qi Zhang, Ziyi Wang, Z. Aw, Peng Chen, Bin Zhou, Ruoke Wang, Xiangyang Ge, Qining Lv, Lin Cheng, Rui Zhang, Y. Wong, Hui-Xin Chen, Haiyan Wang, S. Shan, Xue-Jiao Liao, Xuan-Ling Shi, Lei Liu, J. Chu, Xin-Quan Wang, Zheng Zhang, Lin-Qi Zhang

Nature Immunology

DOI

2022

Deep learning guided optimization of human antibody against SARS-CoV-2 variants with broad neutralization

S. Shan, Shitong Luo, Ziqing Yang, Jun-Xian Hong, Yufeng Su, Fan Ding, L. Fu, Chenyu Li, Peng Chen, Jianzhu Ma, Xuan-Ling Shi, Qi Zhang, Bonnie Berger, Lin-Qi Zhang, Jian Peng

Proceedings of the National Academy of Sciences of the United States of America

DOI

2022

Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages

Xiao-Man Li, Yongbing Pan, Qiang-Ling Yin, Zejun Wang, S. Shan, Lai-Xing Zhang, Jin-Fang Yu, Yuanyuan Qu, Lina Sun, Fang Gui, Jia Lu, Zhaofei Jing, Wei Wu, Tao Huang, Xuan-Ling Shi, Jiandong Li, Xinguo Li, De-Xin Li, Shiwen Wang, Mao-Jun Yang, Lin-Qi Zhang, Kai Duan, M. Liang, Xiao-Ming Yang, Xin-Quan Wang

bioRxiv

DOI

2022

Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses

Mingxi Li, Yifei Ren, Z. Aw, Bo Chen, Ziqing Yang, Yuqing Lei, Lin Cheng, Qing Liang, Jun-Xian Hong, Yiling Yang, J. Chen, Y. Wong, Jingjuan Wei, S. Shan, Senyan Zhang, J. Ge, Ruoke Wang, J. Dong, Yu-Xing Chen, Xuan-Ling Shi, Qi Zhang, Zheng Zhang, J. Chu, Xin-Quan Wang, Lin-Qi Zhang

Nature Communications

DOI

2022

SARS-CoV-2 Omicron Variants Reduce Antibody Neutralization and Acquire Usage of Mouse ACE2

Ruoke Wang, Qi Zhang, Rui Zhang, Z. Aw, Peng Chen, Y. Wong, Jun-Xian Hong, B. Ju, Xuan-Ling Shi, Qiang Ding, Zheng Zhang, J. Chu, Lin-Qi Zhang

Frontiers in Immunology

DOI

2022

RBD trimer mRNA vaccine elicits broad and protective immune responses against SARS-CoV-2 variants

Qing Liang, Yifeng Wang, Shu-Yuan Zhang, Jing Sun, Wen-Bo Sun, Ji-Zhou Li, Yaping Liu, Mingxi Li, Lin Cheng, Yuhang Jiang, Ruoke Wang, Rui Zhang, Zihan Yang, Yifei Ren, Peng Chen, Peng Gao, Huayuan Yan, Zheng Zhang, Qi Zhang, Xuan-Ling Shi, Jianbin Wang, Wanli Liu, Xin-Quan Wang, Bo Ying, Jin-Cun Zhao, Hai-Hua Qi, Lin-Qi Zhang

iScience

DOI

2021

Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry

J. Ge, Ruoke Wang, B. Ju, Qi Zhang, Jing Sun, Peng Chen, Senyan Zhang, Yuling Tian, S. Shan, Lin Cheng, Bingjie Zhou, Shuo Song, Juan-Juan Zhao, Haiyan Wang, Xuan-Ling Shi, Q. Ding, Lei Liu, Jin-Cun Zhao, Zheng Zhang, Xin-Quan Wang, Lin-Qi Zhang

Nature Communications

DOI

2021

SARS-CoV-2 variants resist antibody neutralization and broaden host ACE2 usage

Ruoke Wang, Qi Zhang, J. Ge, W. Ren, Rui Zhang, J. Lan, B. Ju, B. Su, Feng-Ting Yu, Peng Chen, Hui-Wen Liao, Yingmei Feng, Xuemei Li, Xuan-Ling Shi, Zheng Zhang, Fu-Jie Zhang, Q. Ding, Tong Zhang, Xin-Quan Wang, Lin-Qi Zhang

bioRxiv

DOI

2021

A potent and protective human neutralizing antibody targeting a novel vulnerable site of Epstein-Barr virus

Qianying Zhu, S. Shan, Jin-Fang Yu, S. Peng, Cong Sun, Y. Zuo, L. Zhong, Shu-Mei Yan, Xiao Zhang, Ziqing Yang, Yong-Jian Peng, Xuan-Ling Shi, S. Cao, Xin-Quan Wang, Mu-Sheng Zeng, Lin-Qi Zhang

Nature Communications

DOI

2021

Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species

Ruoke Wang, Qi Zhang, J. Ge, W. Ren, Rui Zhang, J. Lan, B. Ju, B. Su, Feng-Ting Yu, Peng Chen, Hui-Wen Liao, Yingmei Feng, Xuemei Li, Xuan-Ling Shi, Zheng Zhang, Fu-Jie Zhang, Q. Ding, Tong Zhang, Xin-Quan Wang, Lin-Qi Zhang

Immunity

DOI

2021

A Potent and Protective Human Neutralizing Antibody Against SARS-CoV-2 Variants

S. Shan, Chee-Keng Mok, Shu-Yuan Zhang, J. Lan, Ji-Zhou Li, Ziqing Yang, Ruoke Wang, Lin Cheng, Mengqi Fang, Z. Aw, Jin-Fang Yu, Qi Zhang, Xuan-Ling Shi, Tong Zhang, Zheng Zhang, Jianbin Wang, Xin-Quan Wang, J. Chu, Lin-Qi Zhang

Frontiers in Immunology

DOI

2021

Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2

Qi Zhang, B. Ju, J. Ge, J. Chan, Lin Cheng, Ruoke Wang, Wei-Jing Huang, Mengqi Fang, Peng Chen, Bingjie Zhou, Shuo Song, S. Shan, Baohua Yan, Senyan Zhang, Xiangyang Ge, Jia-Zheng Yu, Juanjuan Zhao, Haiyan Wang, Li Liu, Qining Lv, L. Fu, Xuan-Ling Shi, Kwok Y. Yuen, Lei Liu, You-Chun Wang, Zhi-Wei Chen, Lin-Qi Zhang, Xin-Quan Wang, Zheng Zhang

Nature Communications

DOI

2021

Single-Dose Immunization With a Chimpanzee Adenovirus-Based Vaccine Induces Sustained and Protective Immunity Against SARS-CoV-2 Infection

Mingxi Li, Jingao Guo, Shuai-Yao Lu, Run-Hong Zhou, Hong-Yan Shi, Xuan-Ling Shi, Lin Cheng, Qing Liang, Hong-Qi Liu, Pui Wang, Nan Wang, Yifeng Wang, L. Fu, Man Xing, Ruoke Wang, B. Ju, Li Liu, Siu-Ying Lau, Wenxu Jia, Xin Tong, L. Yuan, Yong Guo, Hai-Hua Qi, Qi Zhang, Zhen Huang, Hong-Lin Chen, Zheng Zhang, Zhi-Wei Chen, Xiao-Zhong Peng, Dongming Zhou, Lin-Qi Zhang

Frontiers in Immunology

DOI

2020

HIV-1感染长期不进展者中env基因准种序列和中和活性相关性

陈敏，戴洁，傅莉莉，陈会超，董莉娟，金晓媚，杨敏，史宣玲，马艳玲

《中国艾滋病性病》

2020

Human neutralizing antibodies elicited by SARS-CoV-2 infection

B. Ju, Qi Zhang, J. Ge, Ruoke Wang, Jing Sun, Xiangyang Ge, Jia-Zheng Yu, S. Shan, Bingjie Zhou, Shuo Song, Xianchun Tang, Jin-Fang Yu, J. Lan, Jing Yuan, Haiyan Wang, Juan-Juan Zhao, Shu-Ye Zhang, You-Chun Wang, Xuan-Ling Shi, Lei Liu, Jin-Cun Zhao, Xin-Quan Wang, Zheng Zhang, Lin-Qi Zhang

Nature

DOI

2020

Stabilized diverse HIV-1 envelope trimers for vaccine design

Qian Wang, B. Ma, Qing Liang, A. Zhu, Hua Wang, L. Fu, Xiaoxu Han, Xuan-Ling Shi, Ye Xiang, H. Shang, Lin-Qi Zhang

Emerging Microbes and Infections

DOI

2020

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

J. Lan, J. Ge, Jin-Fang Yu, S. Shan, Huan Zhou, S. Fan, Qi Zhang, Xuan-Ling Shi, Qisheng Wang, Lin-Qi Zhang, Xin-Quan Wang

Nature

DOI

2020

Establishment of replication-competent vesicular stomatitis virus-based recombinant viruses suitable for SARS-CoV-2 entry and neutralization assays

Hong-Yue Li, Chaoyue Zhao, Yuhang Zhang, Fei Yuan, Qi Zhang, Xuan-Ling Shi, Lin-Qi Zhang, C. Qin, Aihua Zheng

Emerging Microbes and Infections

DOI

2020

Epstein-Barr virus (EBV) is the causative agent of a wide range of diseases

Qianying Zhu, S. Shan, Jin-Fang Yu, S. Peng, Cong Sun, Yanan, Zuo, Shu-Mei Yan, Xiao Zhang, Ziqing Yang, L. Zhong, Xuan-Ling Shi, S. Cao, Xin-Quan Wang, Mu-Sheng Zeng, Lin-Qi Zhang

2019

“免疫艾滋病基因编辑婴儿”的问题与危害

史宣玲，张林琦

《医学与哲学》

2019

云南省142例HIV-1感染长期不进展者的病毒学和中和活性抗体分析

陈敏，戴洁，傅莉莉，陈会超，董莉娟，杨敏，史宣玲，马艳玲

《现代预防医学》

2019

Antibodies and vaccines against Middle East respiratory syndrome coronavirus

Jiu-Yang Xu, Wenxu Jia, Peng-Fei Wang, Senyan Zhang, Xuan-Ling Shi, Xin-Quan Wang, Lin-Qi Zhang

Emerging Microbes and Infections

DOI

2019

Development of a Potent and Protective Germline-Like Antibody Lineage Against Zika Virus in a Convalescent Human

F. Gao, Xiao-He Lin, Linling He, Ruoke Wang, Han Wang, Xuan-Ling Shi, Fuchun Zhang, Chi-Biao Yin, Lin-Qi Zhang, Jiang Zhu, Lei Yu

bioRxiv

DOI

2019

Structural Basis for Neutralization and Protection by a Zika Virus-Specific Human Antibody.

Lin Wang, Ruoke Wang, Lei Wang, H. Ben, Lei Yu, F. Gao, Xuan-Ling Shi, Chi-Biao Yin, Fuchun Zhang, Ye Xiang, Lin-Qi Zhang

Cell Reports

DOI

2019

Correction: Complementary recognition of the receptor-binding site of highly pathogenic H5N1 influenza viruses by two human neutralizing antibodies.

Y. Zuo, Peng-Fei Wang, Jian-Feng Sun, Shi-Chun Guo, Guiqin Wang, Teng Zuo, S. Fan, P. Zhou, M. Liang, Xuan-Ling Shi, Xin-Quan Wang, Lin-Qi Zhang

Journal of Biological Chemistry

DOI

2019

Single intranasal immunization with chimpanzee adenovirus-based vaccine induces sustained and protective immunity against MERS-CoV infection

Wenxu Jia, R. Channappanavar, Chao Zhang, Mingxi Li, Hai-Xia Zhou, Shu-Yuan Zhang, Panpan Zhou, Jiu-Yang Xu, S. Shan, Xuan-Ling Shi, Xin-Quan Wang, Jin-Cun Zhao, Dongming Zhou, S. Perlman, Lin-Qi Zhang

Emerging Microbes and Infections

DOI

2019

A Single Substitution in gp41 Modulates the Neutralization Profile of SHIV during In Vivo Adaptation.

Qian Wang, Li-Hong Liu, Wuze Ren, A. Gettie, Hua Wang, Qing Liang, Xuan-Ling Shi, D. Montefiori, Tongqing Zhou, Lin-Qi Zhang

Cell Reports

DOI

2019

Structural and functional definition of a vulnerable site on the hemagglutinin of highly pathogenic avian influenza A virus H5N1

Peng-Fei Wang, Y. Zuo, Jian-Feng Sun, Teng Zuo, Senyan Zhang, Shi-Chun Guo, Xuan-Ling Shi, M. Liang, P. Zhou, Lin-Qi Zhang, Xin-Quan Wang

Journal of Biological Chemistry

DOI

2019

Broadly resistant HIV-1 against CD4-binding site neutralizing antibodies

Panpan Zhou, Han Wang, Mengqi Fang, Yangyang Li, Hua Wang, Shasha Shi, Zi-Hao Li, Jia-Peng Wu, Xiaoxu Han, Xuan-Ling Shi, H. Shang, Tongqing Zhou, Lin-Qi Zhang

PLoS Pathogens

DOI

2018

构象锁定HIV-1融合抑制剂的合成及抗HIV-1活性研究

Ye Guo, L. Fu, Xiao-Wen Fan, Xuan-Ling Shi

DOI

2018

抗人CD4单克隆抗体制备及其抗HIV-1功能鉴定

李岚，史宣玲，江立玮，殷昌斌，李家伟，刘巍

《中国病毒病杂志》

2018

Stapled SC34EK fusion inhibitors with high potency against HIV-1 and improved protease resistance

Ye Guo, L. Fu, Xiao-Wen Fan, Xuan-Ling Shi

Chinese Chemical Letters

DOI

2018

on Receptor-Binding of Spike

Senyan Zhang, Panpan Zhou, Peng-Fei Wang, Yangyang Li, Li-Wei Jiang, Wenxu Jia, Han Wang, A. Fan, Dongli Wang, Xuan-Ling Shi, Xian-Yang Fang, Michal Hammel, Shu-Ying Wang, Xin-Quan Wang, Lin-Qi Zhang

2018

Complementary recognition of the receptor-binding site of highly pathogenic H5N1 influenza viruses by two human neutralizing antibodies

Y. Zuo, Peng-Fei Wang, Jian-Feng Sun, Shi-Chun Guo, Guiqin Wang, Teng Zuo, S. Fan, P. Zhou, M. Liang, Xuan-Ling Shi, Xin-Quan Wang, Lin-Qi Zhang

Journal of Biological Chemistry

DOI

2018

Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein

Senyan Zhang, Panpan Zhou, Peng-Fei Wang, Yangyang Li, Li-Wei Jiang, Wenxu Jia, Han Wang, A. Fan, Dongli Wang, Xuan-Ling Shi, X. Fang, M. Hammel, Shuying Wang, Xin-Quan Wang, Lin-Qi Zhang

Cell Reports

DOI

2018

A Single Injection of Human Neutralizing Antibody Protects against Zika Virus Infection and Microcephaly in Developing Mouse Embryos

Cui Li, F. Gao, Lei Yu, Ruoke Wang, Yisheng Jiang, Xuan-Ling Shi, Chi-Biao Yin, Xiao-Ping Tang, Fuchun Zhang, Zhiheng Xu, Lin-Qi Zhang

Cell Reports

DOI

2018

DeepHINT: understanding HIV-1 integration via deep learning with attention

Hailin Hu, An Xiao, Sai Zhang, Yangyang Li, Xuanling Shi, Tao Jiang, Linqi Zhang, Lei Zhang, Lei Zhang, Lei Zhang, Jianyang Zeng

Bioinformatics

DOI

2017

Epitope-focused immunogens against the CD4-binding site of HIV-1 envelope protein induce neutralizing antibodies against auto- and heterologous viruses

Hua Wang, Xiang-Jun Chen, Dianhong Wang, Chen Yao, Qian Wang, Jia-Yu Xie, Xuan-Ling Shi, Ye Xiang, Wan-Li Liu, Lin-Qi Zhang

Journal of Biological Chemistry

DOI

2017

TALEN-Mediated Knockout of CCR5 Confers Protection Against Infection of Human Immunodeficiency Virus

Bing-Jie Shi, Juan Li, Xuan-Ling Shi, Wenxu Jia, Yi Wen, Xiong-Bing Hu, Feng-Feng Zhuang, J. Xi, Lin-Qi Zhang

Journal of Acquired Immune Deficiency Syndromes

DOI

2017

Delineating antibody recognition against Zika virus during natural infection.

Lei Yu, Ruoke Wang, F. Gao, Min Li, Jianying Liu, Jian Wang, Wen-Xin Hong, Ling-Zhai Zhao, Yingfen Wen, Chi-Biao Yin, Hua Wang, Qi Zhang, Yangyang Li, Panpan Zhou, Ru-Dian Zhang, Yang Liu, Xiao-Ping Tang, Y. Guan, Cheng-Feng Qin, Ling Chen, Xuan-Ling Shi, Xia Jin, G. Cheng, Fuchun Zhang, Lin-Qi Zhang

JCI Insight

DOI

2016

Spatiotemporal hierarchy in antibody recognition against transmitted HIV-1 envelope glycoprotein during natural infection

Su Jin, Yangtao Ji, Qian Wang, Hua Wang, Xuan-Ling Shi, Xiaoxu Han, Tongqing Zhou, H. Shang, Lin-Qi Zhang

Retrovirology

DOI

2016

Potent neutralizing monoclonal antibodies against Ebola virus infection

Qi Zhang, M. Gui, X. Niu, Shi-Hua He, Ruoke Wang, Yu-Peng Feng, A. Kroeker, Y. Zuo, Hua Wang, Ying Wang, Jiade Li, Chu-Fang Li, Yi Shi, Xuan-Ling Shi, G. Gao, Y. Xiang, X. Qiu, Ling Chen, Lin-Qi Zhang

Scientific Reports

DOI

2016

Erratum: Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection

Teng Zuo, Jian-Feng Sun, Guiqin Wang, Li-Wei Jiang, Y. Zuo, Danyang Li, Xuan-Ling Shi, Xi Liu, S. Fan, Huanhuan Ren, Hongxing Hu, Lina Sun, Bo-Ping Zhou, M. Liang, P. Zhou, Xin-Quan Wang, Lin-Qi Zhang

Nature Communications

DOI

2015

云南省长期不进展HIV感染者病毒载量和CD4+T淋巴细胞计数与中和抗体活性相关性分析

郭敏，陈敏，史宣玲，贾曼红，戴洁，傅莉莉，马艳玲，罗红兵，韦焘，李彩霞，徐洪吕，陆林

《中国皮肤性病学杂志》

2015

J. Biol. Chem.-2011-Zuo-33511-9[1]

Teng Zuo, Xuan-Ling Shi, Zhong-Hua Liu, Lin-Lin Guo, Qing Zhao, Tian-Xia Guan, Xianming Pan, Na Jia, Wuchun Cao, Boping Zhou, M. Goldin, Lin-Qi Zhang

2015

Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection

Teng Zuo, Jian-Feng Sun, Guiqin Wang, Li-Wei Jiang, Y. Zuo, Danyang Li, Xuan-Ling Shi, Xi Liu, S. Fan, Huanhuan Ren, Hongxing Hu, Lina Sun, Bo-Ping Zhou, M. Liang, P. Zhou, Xin-Quan Wang, Lin-Qi Zhang

Nature Communications

DOI

2015

Combinatorial library-based profiling of the antibody response against hepatitis C virus in humans.

Kan Luo, Shu Li, Li-Wei Jiang, Teng Zuo, Jie Qing, Xuan-Ling Shi, Ya-Li Liu, Hao Wu, Xin-Yue Chen, Lin-Qi Zhang

Journal of General Virology

DOI

2015

Structural basis for the neutralization of MERS-CoV by a human monoclonal antibody MERS-27

Xiaojuan Yu, Senyan Zhang, Li-Wei Jiang, Ye Cui, Dong-Xiao Li, Dongli Wang, Nian-Shuang Wang, L. Fu, Xuan-Ling Shi, Zi-qiang Li, Lin-Qi Zhang, Xin-Quan Wang

Scientific Reports

DOI

2014

HIV-1假病毒包装方法的探讨

徐树莹，乔录新，史宣玲，徐萌，魏飞力，袁霖，石英，陈德喜

《中华实验和临床感染病杂志(电子版)》

2014

Potent Neutralization of MERS-CoV by Human Neutralizing Monoclonal Antibodies to the Viral Spike Glycoprotein

Li-Wei Jiang, Nian-Shuang Wang, Teng Zuo, Xuan-Ling Shi, K. Poon, Yong-Kang Wu, Fei Gao, Danyang Li, Ruoke Wang, Jian-Ying Guo, L. Fu, Kwok Y. Yuen, B. Zheng, Xin-Quan Wang, Lin-Qi Zhang

Science Translational Medicine

DOI

2014

Complex structure of MERS-CoV spike glycoprotein with human receptor DPP4

Nian-Shuang Wang, Li-Wei Jiang, Xuan-Ling Shi, K. Poon, Kwok Y. Yuen, B. Zheng, Lin-Qi Zhang, Xin-Quan Wang

DOI

2014

Identification of residues on human receptor DPP4 critical for MERS-CoV binding and entry

Wen-Fei Song, Ying Wang, Nian-Shuang Wang, Dongli Wang, Jian-Ying Guo, L. Fu, Xuan-Ling Shi

Virology

DOI

2013

Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4

Nian-Shuang Wang, Xuan-Ling Shi, Li-Wei Jiang, Senyan Zhang, Dongli Wang, P. Tong, D. Guo, L. Fu, Ye Cui, Xi Liu, Kelly C. Arledge, Ying-Hua Chen, Lin-Qi Zhang, Xin-Quan Wang

Cell Research

DOI

2013

Persistence of VRC01-resistant HIV-1 during antiretroviral therapy

D. Guo, Xuan-Ling Shi, D. Song, Lin-Qi Zhang

Science China Life Sciences

DOI

2013

Mers-27 monoclonal antibody genes and their applications

Lin-Qi Zhang, Xin-Quan Wang, Li-Wei Jiang, Nian-Shuang Wang, Xuan-Ling Shi, Teng Zuo

2013

RBD (receptor binding domain) segment in MERS-CoV (Middle East respiratory syndrome coronavirus) membrane protein and coding gene and application thereof

Xin-Quan Wang, Lin-Qi Zhang, Nian-Shuang Wang, Xuan-Ling Shi

2013

Monoclonal antibody MERS-27, as well as coding gene and application thereof

Lin-Qi Zhang, Xin-Quan Wang, Li-Wei Jiang, Nian-Shuang Wang, Xuan-Ling Shi, Teng Zuo

2013

Role of Human CD4 D1D2 Domain in HIV-1 Infection

Lan Li, Xuan-Ling Shi, Qingyu Lu, Senyan Zhang, Xin-Quan Wang, Xu Jiang, Yi-Feng Liu, Guan-Shi Wang, Wei-jun Zhu, Rongyue Lei, Hao Wu

Immunological Investigations

DOI

2012

V5 region in the HIV-1 envelope glycoprotein determines viral sensitivity to the broadly neutralizing monoclonal antibody VRC01

D. Guo, Xuan-Ling Shi, Kelly C. Arledge, D. Song, L. Jiang, L. Fu, S. Zhang, X. Wang, Li Zhang

Retrovirology

DOI

2012

A Single Residue within the V5 Region of HIV-1 Envelope Facilitates Viral Escape from the Broadly Neutralizing Monoclonal Antibody VRC01*

D. Guo, Xuan-Ling Shi, Kelly C. Arledge, D. Song, Li-Wei Jiang, L. Fu, Xin-Qi Gong, Senyan Zhang, Xin-Quan Wang, Lin-Qi Zhang

Journal of Biological Chemistry

DOI

2011

HIV-1中国流行株假病毒的建立及其初步应用

孙伟，王蕊，史宣玲，傅阿丽，焦艳梅，吴昊

《中国病毒病杂志》

2011

Comprehensive Analysis of Pathogen-specific Antibody Response in Vivo Based on an Antigen Library Displayed on Surface of Yeast*

Teng Zuo, Xuan-Ling Shi, Zhong-Hua Liu, Lin-Lin Guo, Qing Zhao, Tian-Xia Guan, Xianming Pan, Na Jia, Wuchun Cao, Bo-Ping Zhou, M. Goldin, Lin-Qi Zhang

Journal of Biological Chemistry

DOI

2011

Genetic and Neutralization Sensitivity of Diverse HIV-1 env Clones from Chronically Infected Patients in China*

H. Shang, Xiaoxu Han, Xuan-Ling Shi, Teng Zuo, M. Goldin, Dan Chen, Bing Han, Wei Sun, Hao Wu, Xin-Quan Wang, Lin-Qi Zhang

Journal of Biological Chemistry

DOI

2011

Rapid Turnover of 2-LTR HIV-1 DNA during Early Stage of Highly Active Antiretroviral Therapy

Wei-jun Zhu, Yan-Mei Jiao, Rongyue Lei, Wei Hua, Rui Wang, Yun-Xia Ji, Zhiying Liu, F. Wei, Tong Zhang, Xuan-Ling Shi, Hao Wu, Lin-Qi Zhang

PLoS ONE

DOI

2009

Recruitment of a SAP18-HDAC1 Complex into HIV-1 Virions and Its Requirement for Viral Replication

Masha Sorin, J. Cano, Supratik Das, Sheeba Mathew, Xuhong Wu, K. Davies, Xuan-Ling Shi, S. Cheng, D. Ott, G. Kalpana

PLoS Pathogens

DOI

2007

SARS冠状病毒Nsp14基因的克隆与表达

刘杰，成子强，史宣玲

《微生物学通报》

2007

Instability of retroviral vectors with HIV-1-specific RT aptamers due to cryptic splice sites in the U6 promoter

S. E. Braun, Xuan-Ling Shi, Gang Qiu, Fay E. Wong, P. Joshi, Vinayaka R. Prasad, RPaul Johnson

AIDS Research and Therapy

DOI

2006

丙型肝炎病毒感染的献血者12年追踪观察

季阳，贾桂芳，刘福荣，郑鹏，任勤惠，朱志义，史宣玲，倪声全，徐钢，杜琼，饶绍琴，庄文

《中国输血杂志》

2004

Neutralizing Antibodies in Patients with Severe Acute Respiratory Syndrome-Associated Coronavirus Infection

Yuchun Nie, Guangwen Wang, Xuan-Ling Shi, Hong Zhang, Yan Qiu, Zhongping He, Wei Wang, Gewei Lian, Xiaolei Yin, Liying Du, L. Ren, Jianwei Wang, Xiong He, Tai-Sheng Li, H. Deng, M. Ding

Journal of Infectious Diseases

DOI

2004

Suppression of SARS-CoV entry by peptides corresponding to heptad regions on spike glycoprotein

Ke-Hu Yuan, L. Yi, Jian Chen, Xiuxia Qu, T. Qing, Susie Xi Rao, Peng-Fei Jiang, Jian-He Hu, Z. Xiong, Yuchun Nie, Xuan-Ling Shi, Wei Wang, Chen Ling, Xiaolei Yin, K. Fan, L. Lai, M. Ding, H. Deng

Biochemical and Biophysical Research Communications - BBRC

DOI

2004

Small Molecules Blocking the Entry of Severe Acute Respiratory Syndrome Coronavirus into Host Cells

L. Yi, Zheng-Quan Li, Ke-Hu Yuan, Xiuxia Qu, Jian Chen, Guangwen Wang, Hong Zhang, Hong-Peng Luo, Lili Zhu, Peng-Fei Jiang, Li-Rong Chen, Yan Shen, Min Luo, Guoying Zuo, Jian-He Hu, Deliang Duan, Yuchun Nie, Xuan-Ling Shi, Wei Wang, Yang Han, Tai-Sheng Li, Yuqing Liu, M. Ding, H. Deng, Xiao-Jie Xu

Journal of Virology

DOI

2004

Highly infectious SARS-CoV pseudotyped virus reveals the cell tropism and its correlation with receptor expression

Yuchun Nie, Peigang Wang, Xuan-Ling Shi, Guangwen Wang, Jian Chen, Aihua Zheng, Wei Wang, Zai Wang, Xiuxia Qu, Min Luo, Lei Tan, Xi-Jun Song, Xiaolei Yin, Jian-Guo Chen, M. Ding, H. Deng

Biochemical and Biophysical Research Communications - BBRC

DOI

2004

Expression cloning of functional receptor used by SARS coronavirus

Peigang Wang, Jian Chen, Aihua Zheng, Yuchun Nie, Xuan-Ling Shi, Wei Wang, Guangwen Wang, Min Luo, Huijun Liu, Lei Tan, Xi-Jun Song, Zai Wang, Xiaolei Yin, Xiuxia Qu, Xiaojing Wang, T. Qing, M. Ding, H. Deng

Biochemical and Biophysical Research Communications - BBRC

DOI

2004

Identification of an Antigenic Determinant on the S2 Domain of the Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein Capable of Inducing Neutralizing Antibodies

Hong Zhang, Guangwen Wang, Jian Li, Yuchun Nie, Xuan-Ling Shi, Gewei Lian, Wei Wang, Xiaolei Yin, Yang Zhao, Xiuxia Qu, M. Ding, H. Deng

Journal of Virology

DOI

2003

丙型肝炎病毒感染献血者8年追踪观察

季阳，贾桂芳，周琼秀，刘福荣，倪声全，彭登厚，文锦，任勤惠，朱志义，史宣玲，周义英，马义才

《医学研究杂志》

2002

HCV包膜蛋白E2的B细胞抗原模拟表位的筛选、重组表达与抗原性鉴定

史宣玲，曹凤，季阳，杜勇，侯利华，王海涛

《中国输血杂志》

2001

丙型肝炎病毒E1基因在COS-7中的表达

曹凤，史宣玲，杜勇，侯利华，季阳，王海涛

《华西医学》

2001

丙型肝炎病毒包膜区E2基因的克隆、表达及其感染者中E2抗体检测的意义

史宣玲，曹凤，季阳，杜勇，侯利华，王海涛

《中国输血杂志》

DOI

2001

丙型肝炎病毒E1蛋白的模拟表位研究

曹凤，史宣玲，杜勇，侯利华，季阳，王海涛

《中华肝脏病杂志》

2000

丙型肝炎病毒E1基因的克隆、表达、序列分析及定点突变

曹凤，史宣玲，季阳，杜勇，侯利华，宋宏彬，王海涛

《中国输血杂志》

2000

丙型肝炎病毒包膜糖蛋白的研究进展

曹凤，史宣玲

《国外医学(微生物学分册)》

2000

输血传播病毒性疾病的研究现状及进展

史宣玲

《国际输血及血液学杂志》

2000

HCV包膜蛋白的免疫与疫苗研究进展

曹凤，史宣玲，王海涛，季阳

《国际病毒学杂志》

1999

对丙型肝炎病毒感染的10名献血者的追踪研究

季阳，任勤惠，朱志议，史宣玲，彭登厚，瞿德敏，倪声全

《中国输血杂志》

DOI

1999

丙型肝炎病毒核酸疫苗的研究进展

史宣玲，曹凤

《国际流行病学传染病学杂志》

1997

HCV感染的献血者血清中病毒量的检测及分析

史宣玲，季阳，任勤惠，朱志议

《中国输血杂志》

1996

献血者发生丙型肝炎后的转归

史宣玲

《国际输血及血液学杂志》

1996

HCV感染的献血者的肝组织学和血清学变化观察

史宣玲，季阳，任勤惠，朱志议，倪声全，彭登厚，胡力

《中国输血杂志》

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