杨慧｜复旦大学｜学者主页

2026

Orai1上调促进血管平滑肌钙化表型转化

梁美英，周维妍，肖佩仪，王昊，杨慧，饶芳，邓春玉

《中国病理生理杂志》

2026

Piezo1激活介导高钙磷诱导的大鼠冠脉平滑肌细胞钙化

蒋柳香，陈美江，胡旭相，杨慧，饶芳，邓春玉

《中国药理学通报》

2025

去甲基化酶FTO基因敲除对5-HT诱导糖尿病冠脉平滑肌收缩功能异常的影响

王梓帆，蒋柳香，梁美英，刘梦云，陈美江，杨慧，饶芳，邓春玉

《中国药理学通报》

2024

敲除Fto基因对糖尿病小鼠主动脉平滑肌收缩及钙调控异常的作用研究

郑燕湘，蔡泳江，王梓帆，邝素娟，杨慧，饶芳，邓春玉

《中国病理生理杂志》

2024

Piezo1通道激活促进大鼠冠脉平滑肌细胞内钙浓度升高的机制研究

蔡泳江，郑燕湘，王梓帆，邝素娟，杨慧，饶芳，邓春玉

《中国病理生理杂志》

2023

甲基化转移酶样蛋白3介导的m6A修饰参与高静水压诱导的心房肌细胞电重塑

刘攀月，曾珑，肖海茵，肖菲菲，朱蕊，杨慧，邝素娟，邓春玉，饶芳，魏薇

《中国药理学通报》

2023

RhoA/ROCK信号通路参与2型糖尿病小鼠主动脉收缩高反应的机制

陈淑贞，蔡泳江，郑燕湘，秦晓玥，邝素娟，杨慧，饶芳，邓春玉

《中国药理学通报》

2022

机械敏感性离子通道Piezo1介导高静水压诱导大鼠冠脉平滑肌细胞表型改变

李穗敏，秦晓玥，曾鹏，陈淑贞，邝素娟，杨慧，饶芳，邓春玉

《中国药理学通报》

2022

Orai1通道在高血压大鼠心房纤维化中的作用机制研究

梁海丹，杨慧，李倩，秦晓玥，李穗敏，陈淑贞，邝素娟，饶芳，邓春玉

《中国病理生理杂志》

2022

钙感受器STIM1参与主动脉平滑肌细胞衰老的作用研究

曾鹏，秦晓玥，王义蓉，李穗敏，陈淑贞，邝素娟，杨慧，饶芳，邓春玉

《中国病理生理杂志》

2022

机械力敏感离子通道Piezo1参与高血压诱导心房纤维化的机制研究

刘慧意，饶芳，叶兴东，金书羽，付路，邓春玉，杨慧，邝素娟，吴书林，薛玉梅

《中国病理生理杂志》

2022

钙非依赖性磷脂酶A2在肾内动脉平滑肌收缩反应中的作用

秦晓玥，李穗敏，曾鹏，陈淑贞，王义蓉，邝素娟，杨慧，饶芳，邓春玉

《中国药理学通报》

2022

The hippo kinase MST1 negatively regulates the differentiation of follicular helper T cells

Lin Dong, Yejin Cao, Hui Yang, Yueru Hou, Ying He, Yufei Wang, Qiuli Yang, Yujing Bi, Guangwei Liu

Immunology

DOI

2022

Dendritic cell Piezo1 directs the differentiation of TH1 and Treg cells in cancer

Yuexin Wang, Hui Yang, Anna Jia, Yufei Wang, Qiuli Yang, Yingjie Dong, Yueru Hou, Yejin Cao, Lin Dong, Yujing Bi, Guangwei Liu

eLife

DOI

2022

Protein Tyrosine Phosphatase PTPRO Signaling Couples Metabolic States to Control the Development of Granulocyte Progenitor Cells

Yan Li, Anna Jia, Hui Yang, Yuexin Wang, Yufei Wang, Qiuli Yang, Yejin Cao, Yujing Bi, Guangwei Liu

The Journal of Immunology

DOI

2021

p300在老年小鼠心房颤动易感性中的作用研究

彭德威，周慧珊，刘海燕，高小燕，赖颖瑜，李巧巧，邓春玉，杨慧，邝素娟，薛玉梅，吴书林，饶芳

《中国药理学通报》

2021

2型糖尿病大鼠心室肌细胞离子通道功能和表达变化

刘沛明，郑丹琳，张利，周梦园，练飞鸿，邝素娟，杨慧，饶芳，邓春玉

《中国病理生理杂志》

2021

DNA加双氧酶TET1在高压诱导心肌纤维化中的作用研究

李路安，吴清蕊，李倩，饶芳，邝素娟，杨慧，张黔桓，张斌

《中国药理学通报》

2021

钙感受器STIM1在小鼠主动脉平滑肌收缩反应中的作用研究

周梦园，张利，曾鹏，秦晓玥，郑丹琳，李穗敏，邝素娟，杨慧，饶芳，邓春玉

《中国药理学通报》

2021

1型糖尿病小鼠心房肌细胞电重塑及AGE对其的影响

郑丹琳，刘沛明，张利，周梦园，曾鹏，李穗敏，秦晓玥，梁海丹，邝素娟，杨慧，饶芳，邓春玉

《中国药理学通报》

2020

Drp1在高糖诱导的大鼠心肌细胞肥大中的作用研究

吴清蕊，练飞鸿，饶芳，邝素娟，杨慧，吴飞龙，张梦珍，麦丽萍，林秋雄，单志新，杨敏，邓春玉

《中国病理生理杂志》

2020

NKT细胞通过下调PDGFRβ抑制Ang Ⅱ诱导的小鼠血管平滑肌细胞表型转换

肖雪，侯翠柳，王筱筱，陈立瑞，杨慧，田翠，王红霞

《中国病理生理杂志》

2019

Immune effects of glycolysis or oxidative phosphorylation metabolic pathway in protecting against bacterial infection

Yan Li, Anna Jia, Yuexin Wang, Lin Rui Dong, Yufei Wang, Ying He, Shiyao Wang, Yejin Cao, Hui Yang, Yujing Bi, Guangwei Liu

Journal of Cellular Physiology

DOI

2018

5-羟色胺诱导冠状动脉收缩的机制研究

王昊，邓春玉，饶芳，邝素娟，杨慧，刘林，吴琪，徐劲松

《中国病理生理杂志》

2018

2型糖尿病大鼠心功能变化及RAGE表达增强和钙调控异常

练飞鸿，饶芳，邝素娟，陈肖燕，杨慧，吴飞龙，张梦珍，麦丽萍，林秋雄，单志新，杨敏，邓春玉

《中国病理生理杂志》

2018

L-型钙通道参与大鼠动脉收缩反应的异质性

刘林，邝素娟，杨慧，饶芳，张梦珍，麦丽萍，林秋雄，单志新，杨敏，邓春玉

《中国药理学通报》

2018

HIF1α-dependent glycolysis promotes macrophage functional activities in protecting against bacterial and fungal infection

Chunxiao Li, Yu Wang, Yan Li, Qing Yu, Xi Jin, Xiao Wang, Anna Jia, Ying Hu, Linian Han, Jian Wang, Hui Yang, Dapeng Yan, Yujing Bi, Guangwei Liu

Scientific Reports

DOI

2017

毒胡萝卜素诱导大鼠冠状动脉平滑肌细胞内质网应激模型的建立

陈肖燕，邓春玉，邝素娟，杨慧，饶芳，单志新，林秋雄，姜立

《中国病理生理杂志》

2017

Glucocorticoid receptor promotes the function of myeloid-derived suppressor cells by suppressing HIF1α-dependent glycolysis

Yun Lu, Huanrong Liu, Yujing Bi, Hui Yang, Yan Li, Jian Wang, Zhengguo Zhang, Yu Wang, Chunxiao Li, Anna Jia, Linian Han, Ying Hu, Yong Xiang Zhao, Ruoning Wang, Guangwei Liu

Cellular and Molecular Immunology

DOI

2017

Dendritic cell MST1 inhibits Th17 differentiation

Chunxiao Li, Yujing Bi, Yan Li, Hui Yang, Qing Yu, Jian Wang, Yu Wang, Huilin Su, Anna Jia, Ying Hu, Linian Han, Jiangyuan Zhang, Simin Li, Wufan Tao, Guangwei Liu

Nature Communications

DOI

2016

circRNA000203对小鼠心肌成纤维细胞纤维化表型的影响

朱文思，唐春梅，朱杰宁，林秋雄，符永恒，邓春玉，杨慧，饶芳，吴书林，单志新

《中国病理生理杂志》

2016

人肺内微小动脉体外培养模型的建立及其收缩特性的观察

邝素娟，杨慧，李晓红，刘晓颖，饶芳，单志新，林秋雄，杨敏，余细勇，吴书林，邓春玉

《中国病理生理杂志》

2016

Orai1通道调控内质网应激反应参与糖尿病血管内皮损伤

杨慧，邝素娟，饶芳，薛玉梅，单志新，林秋雄，杨敏，吴书林，邓春玉

《中国病理生理杂志》

2016

mTOR signaling disruption from myeloid-derived suppressive cells protects against immune-mediated hepatic injury through the HIF1α-dependent glycolytic pathway

Xi Chen, Zhengguo Zhang, Yujing Bi, Zan Fu, Pingsheng Gong, Yan Li, Qing Yu, Anna Jia, Jian Wang, Lixiang Xue, Hui Yang, Guangwei Liu

Journal of Leukocyte Biology

DOI

2016

Histone Deacetylase SIRT1 Negatively Regulates the Differentiation of Interleukin-9-Producing CD4 + T Cells

Yu Wang, Yujing Bi, Xi Chen, Chunxiao Li, Yan Li, Zhengguo Zhang, Jian Wang, Yun Lu, Qing Yu, Huilin Su, Hui Yang, Guangwei Liu

Immunity

DOI

2015

缝隙连接蛋白43通过调控L型钙电流参与心房肌细胞的电重塑

饶芳，薛玉梅，邓春玉，余细勇，肖定璋，陈少贤，林秋雄，杨慧，邝素娟，刘晓颖，朱杰宁，吴书林

《中国病理生理杂志》

2015

TLR2/NLRC5参与棕榈酸诱导的心肌细胞凋亡及相关机制研究

刘晓颖，蔡诗婷，杨敏，萧定璋，谭红红，陈景，陈少贤，陈红梅，杨慧，余细勇

《中国临床药理学与治疗学》

2015

Different Effects of Tacrolimus on Innate and Adaptive Immune Cells in the Allograft Transplantation

K. Shao, Yun Lu, Jingyi Wang, Xiao Chen, Zhaoyun Zhang, Xiao‐Qiu Wang, Xiao‐Qiu Wang, X. Wang, X. Wang, Hui Yang, Gao Liu

Scandinavian Journal of Immunology

DOI

2015

Myeloid-derived suppressor cells in immunity and autoimmunity

Hui Yang, Yujing Bi, Fei Han, Yun Lu, Jian Wang, Zhengguo Zhang, Guangwei Liu

Expert Review of Clinical Immunology

DOI

2015

Intercellular interplay between Sirt1 signalling and cell metabolism in immune cell biology

Xi Chen, Yun Lu, Zhengguo Zhang, Jian Wang, Hui Yang, Guangwei Liu

Immunology

DOI

2015

Dendritic cell SIRT1–HIF1α axis programs the differentiation of CD4 + T cells through IL-12 and TGF-β1

Guangwei Liu, Yujing Bi, Lixiang Xue, Yan Zhang, Hui Yang, Xi Chen, Yun Lu, Zhengguo Zhang, Huanrong Liu, Xiao Qin Wang, Ruoning Wang, Yiwei Chu, Ruifu Yang

Proceedings of the National Academy of Sciences

DOI

2014

离体大鼠冠状动脉的分离培养及张力测定技术

邝素娟，邓春玉，杨慧，饶芳，刘晓颖，张梦珍，朱杰宁，单志新，林秋雄，杨敏，余细勇

《中国药理学通报》

2014

Multifaceted Modulation of SIRT1 in Cancer and Inflammation

Hui Yang, Yujing Bi, Lixiang Xue, Jian Wang, Yun Lu, Zhengguo Zhang, Xi Chen, Yiwei Chu, Ruifu Yang, Ruoning Wang, Guangwei Liu

Critical Reviews™ in Oncogenesis

DOI

2014

The Calcineurin-NFAT Axis Controls Allograft Immunity in Myeloid-Derived Suppressor Cells through Reprogramming T Cell Differentiation

Xiao Wang, Yujing Bi, Lixiang Xue, Jiongbo Liao, Xi Chen, Yun Lu, Zhengguo Zhang, Jian Wang, Huanrong Liu, Hui Yang, Guangwei Liu

Molecular and Cellular Biology

DOI

2014

Cellular metabolism modulation in T lymphocyte immunity

Huanrong Liu, Hui Yang, Xi Chen, Yun Lu, Zhengguo Zhang, Jian Wang, Ming Zhang, Lixiang Xue, Feng Xue, Guangwei Liu

Immunology

DOI

2014

mTOR limits the recruitment of CD11b+Gr1+Ly6Chigh myeloid-derived suppressor cells in protecting against murine immunological hepatic injury

Yan Zhang, Yujing Bi, Hui Yang, Xi Chen, Huanrong Liu, Yun Lu, Zhengguo Zhang, Jiongbo Liao, Shan Yang, Yiwei Chu, Ruifu Yang, Guangwei Liu

Journal of Leukocyte Biology

DOI

2014

Targeting S1P1 Receptor Protects against Murine Immunological Hepatic Injury through Myeloid-Derived Suppressor Cells

Guangwei Liu, Yujing Bi, Ruoning Wang, Hui Yang, Yan Zhang, Xiao Dan Wang, Huanrong Liu, Yun Lu, Zhengguo Zhang, Wanna Chen, Yiwei Chu, Ruifu Yang

The Journal of Immunology

DOI

2013

SIRT1 Limits the Function and Fate of Myeloid-Derived Suppressor Cells in Tumors by Orchestrating HIF-1 α –Dependent Glycolysis

Guangwei Liu, Yujing Bi, Bo Shen, Hui Yang, Yan Zhang, Xiao Wang, Huanrong Liu, Yun Lu, Jiongbo Liao, Xi Chen, Yiwei Chu

Cancer Research

DOI

2013

IL-17A Produced by Neutrophils Protects against Pneumonic Plague through Orchestrating IFN-γ–Activated Macrophage Programming

Yujing Bi, Jiyuan Zhou, Hui Yang, Xiao Wang, Xuecan Zhang, Qiong Wang, Xuecan Zhang, Qiong Wang, Xiaohong Wu, Yafang Tan, Yajun Song, Yafang Tan, Zongmin Du, Huiying Yang, Huiying Yang, Dongsheng Zhou, Yujun Cui, Lei Zhou, Yanfeng Yan, Pingping Zhang, Zhaobiao Guo, Xiaoyi Wang, Xiaoyi Wang, Guangwei Liu, Ruifu Yang

The Journal of Immunology

DOI

2013

Kinase AKT1 Negatively Controls Neutrophil Recruitment and Function in Mice

Guangwei Liu, Yujing Bi, Ruoning Wang, Bo Shen, Yan Zhang, Hui Yang, Xiao Wang, Huanrong Liu, Yun Lu, Fei Han

The Journal of Immunology

DOI

2013

Modulation of TSC-mTOR signaling on immune cells in immunity and autoimmunity

Hui Yang, Xianghui Wang, Yan Zhang, Huanrong Liu, Jiongbo Liao, Kun Shao, Yiwei Chu, Guangwei Liu

Journal of Cellular Physiology

DOI

2013

Kinase AKT controls innate immune cell development and function

Yan Zhang, Xiao Wang, Hui Yang, Huanrong Liu, Yun Lu, Limei Han, Guangwei Liu

Immunology

DOI

2012

大蒜素对大鼠离体肾内动脉血管张力的影响

邝素娟，邓春玉，陈怡静，杨慧，饶芳，单志新，林秋雄，杨敏，林曙光，余细勇

《中国病理生理杂志》

2012

ClC-3依赖性Cl-外流参与TNF-α诱导的血管炎症反应及其机制的研究

杨慧，邓春玉，邝素娟，单志新，林秋雄，关永源，周家国，余细勇

《中国病理生理杂志》

2012

Modulation of macrophage activation and programming in immunity

Guangwei Liu, Hui Yang

Journal of Cellular Physiology

DOI

2007

脂质体包裹尿激酶与D-dimer单抗结合后在血栓模型中靶向溶栓实验

杨慧，王珏，董小黎

《中国病理生理杂志》

精选作品

期刊论文

Orai1上调促进血管平滑肌钙化表型转化

Piezo1激活介导高钙磷诱导的大鼠冠脉平滑肌细胞钙化

去甲基化酶FTO基因敲除对5-HT诱导糖尿病冠脉平滑肌收缩功能异常的影响

敲除Fto基因对糖尿病小鼠主动脉平滑肌收缩及钙调控异常的作用研究

Piezo1通道激活促进大鼠冠脉平滑肌细胞内钙浓度升高的机制研究

甲基化转移酶样蛋白3介导的m6A修饰参与高静水压诱导的心房肌细胞电重塑

RhoA/ROCK信号通路参与2型糖尿病小鼠主动脉收缩高反应的机制

机械敏感性离子通道Piezo1介导高静水压诱导大鼠冠脉平滑肌细胞表型改变

Orai1通道在高血压大鼠心房纤维化中的作用机制研究

钙感受器STIM1参与主动脉平滑肌细胞衰老的作用研究

机械力敏感离子通道Piezo1参与高血压诱导心房纤维化的机制研究

钙非依赖性磷脂酶A2在肾内动脉平滑肌收缩反应中的作用

The hippo kinase MST1 negatively regulates the differentiation of follicular helper T cells

Dendritic cell Piezo1 directs the differentiation of TH1 and Treg cells in cancer

Protein Tyrosine Phosphatase PTPRO Signaling Couples Metabolic States to Control the Development of Granulocyte Progenitor Cells

p300在老年小鼠心房颤动易感性中的作用研究

2型糖尿病大鼠心室肌细胞离子通道功能和表达变化

DNA加双氧酶TET1在高压诱导心肌纤维化中的作用研究

钙感受器STIM1在小鼠主动脉平滑肌收缩反应中的作用研究

1型糖尿病小鼠心房肌细胞电重塑及AGE对其的影响

Drp1在高糖诱导的大鼠心肌细胞肥大中的作用研究

NKT细胞通过下调PDGFRβ抑制Ang Ⅱ诱导的小鼠血管平滑肌细胞表型转换

Immune effects of glycolysis or oxidative phosphorylation metabolic pathway in protecting against bacterial infection

5-羟色胺诱导冠状动脉收缩的机制研究

2型糖尿病大鼠心功能变化及RAGE表达增强和钙调控异常

L-型钙通道参与大鼠动脉收缩反应的异质性

HIF1α-dependent glycolysis promotes macrophage functional activities in protecting against bacterial and fungal infection

毒胡萝卜素诱导大鼠冠状动脉平滑肌细胞内质网应激模型的建立

Glucocorticoid receptor promotes the function of myeloid-derived suppressor cells by suppressing HIF1α-dependent glycolysis

Dendritic cell MST1 inhibits Th17 differentiation

circRNA000203对小鼠心肌成纤维细胞纤维化表型的影响

人肺内微小动脉体外培养模型的建立及其收缩特性的观察

Orai1通道调控内质网应激反应参与糖尿病血管内皮损伤

mTOR signaling disruption from myeloid-derived suppressive cells protects against immune-mediated hepatic injury through the HIF1α-dependent glycolytic pathway

Histone Deacetylase SIRT1 Negatively Regulates the Differentiation of Interleukin-9-Producing CD4 + T Cells

缝隙连接蛋白43通过调控L型钙电流参与心房肌细胞的电重塑

TLR2/NLRC5参与棕榈酸诱导的心肌细胞凋亡及相关机制研究

Different Effects of Tacrolimus on Innate and Adaptive Immune Cells in the Allograft Transplantation

Myeloid-derived suppressor cells in immunity and autoimmunity

Intercellular interplay between Sirt1 signalling and cell metabolism in immune cell biology

Dendritic cell SIRT1–HIF1α axis programs the differentiation of CD4 + T cells through IL-12 and TGF-β1

离体大鼠冠状动脉的分离培养及张力测定技术

Multifaceted Modulation of SIRT1 in Cancer and Inflammation

The Calcineurin-NFAT Axis Controls Allograft Immunity in Myeloid-Derived Suppressor Cells through Reprogramming T Cell Differentiation

Cellular metabolism modulation in T lymphocyte immunity

mTOR limits the recruitment of CD11b+Gr1+Ly6Chigh myeloid-derived suppressor cells in protecting against murine immunological hepatic injury

Targeting S1P1 Receptor Protects against Murine Immunological Hepatic Injury through Myeloid-Derived Suppressor Cells

SIRT1 Limits the Function and Fate of Myeloid-Derived Suppressor Cells in Tumors by Orchestrating HIF-1 α –Dependent Glycolysis

IL-17A Produced by Neutrophils Protects against Pneumonic Plague through Orchestrating IFN-γ–Activated Macrophage Programming

Kinase AKT1 Negatively Controls Neutrophil Recruitment and Function in Mice

Modulation of TSC-mTOR signaling on immune cells in immunity and autoimmunity

Kinase AKT controls innate immune cell development and function

大蒜素对大鼠离体肾内动脉血管张力的影响

ClC-3依赖性Cl-外流参与TNF-α诱导的血管炎症反应及其机制的研究

Modulation of macrophage activation and programming in immunity

脂质体包裹尿激酶与D-dimer单抗结合后在血栓模型中靶向溶栓实验

会议论文

L-型钙通道介导大鼠动脉收缩反应的异质性

CIC-3依赖性Cl - 外流参与TNF-α诱导的血管炎症反应及其机制的研究

降低胞内氯浓度促进内皮炎症反应及其机制

C1C-3依赖性C1-外流参与TNF-α诱导的血管炎症反应及其机制的研究

C1C-3氯通道影响血管炎症反应及其机制

容积调节性氯通道影响血管炎症反应及其机制