樊少华｜复旦大学｜学者主页

期刊论文

2026

Anthropometric and cardio-metabolic trait variation and genetic associations in sub-Saharan Africa.

Matthew E. B. Hansen, Ujani Hazra, Michelle S Kim, Srilakshmi M. Raj, Shaohua Fan, W. Beggs, Sunungouko Wata Mpoloka, G. Mokone, T. Nyambo, D. Meskel, G. Belay, J. Hirbo, A. Ranciaro, Joseph Lachance, Sarah A. Tishkoff

American Journal of Human Genetics

DOI

2026

An East Asian blood eQTL meta-analysis highlights ancestry-matched eQTL resources for complex-trait genetics

Jie Wang, Zhengyuan Li, Ruixian Yang, Ying Yu, Huidan Chang, Leming M. Shi, Liyun Yuan, Fang Zhou, Guoqing Zhang, Jin Li, Shaohua Fan

National Science Review

DOI

2025

Long-read sequencing of 945 Han individuals identifies structural variants associated with phenotypic diversity and disease susceptibility

J. Gong, Hui-Ru Sun, Kaiyuan Wang, Yan-Hui Zhao, Yechao Huang, Qin-Sheng Chen, H. Qiao, Yang Gao, Jialin Zhao, Y. Ling, R. Cao, Jingze Tan, Qi Wang, Yanyun Ma, Jing Li, Jingchun Luo, Si-Jia Wang, Jiu-Cun Wang, Guoqing Zhang, Shu-Hua Xu, F. Qian, Fang Zhou, Hui-Ru Tang, Dali Li, F. Sedlazeck, Li Jin, Y. Guan, Shaohua Fan

Nature Communications

DOI

2025

An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis

Yu-Feng Zhang, Jie Wang, Chuanyou Yi, Yue Su, Zi Yin, Shuxian Zhang, Li Jin, M. Stoneking, Jian Yang, Ke Wang, He Huang, Jin Li, Shaohua Fan

Cell Genomics

DOI

2024

Early to Middle Pleistocene transition shapes the evolution of human-specific mutations associated with height and basal metabolic rate

Yu-Feng Zhang, Jie Wang, Chuanyou Yi, Yue Su, Zi Yin, Shuxian Zhang, Ke Wang, He Huang, Jin Li, Shaohua Fan

bioRxiv

DOI

2024

Integrative functional genomic analyses identify genetic variants influencing skin pigmentation in Africans

Yuanqing Feng, Ning Xie, Fumitaka Inoue, Shaohua Fan, Joshua Saskin, Chao Zhang, Fangyuan Zhang, Matthew E. B. Hansen, T. Nyambo, S. Mpoloka, G. Mokone, Charles Fokunang, G. Belay, A. Njamnshi, Michael S. Marks, Elena Oancea, N. Ahituv, Sarah A. Tishkoff

Nature Genetics

DOI

2024

Unveiling novel genetic variants in 370 challenging medically relevant genes using the long read sequencing data of 41 samples from 19 global populations

Yanfeng Ji, Junfan Zhao, J. Gong, F. Sedlazeck, Shaohua Fan

Zeitschrift für Induktive Abstammungs- und Vererbungslehre

DOI

2023

Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2024

Xue Yiming Shaoqi Congfan Ruifang Yongrong Hui Jinquan Bai Bao Bei Bu Cao Cao Cen Chao Chen Chen Chen Che, X. Bai, Yi-Ming Bao, Shao-Qi Bei, Cong-Fan Bu, Ruifang Cao, Yong-Rong Cao, H. Cen, Jinquan Chao, Fei Chen, Huanxin Chen, Kai Chen, Mei-Li Chen, Miao-Miao Chen, Ming Chen, Qian Chen, Run-Sheng Chen, Shuo Chen, Tingting Chen, Xiao-Ning Chen, Xu Chen, Yuan-Yuan Cheng, Y. Chu, Qinghua Cui, Li-Li Dong, Zhenglin Du, Guangya Duan, Shaohua Fan, Zhuo-Jing Fan, Xiang-Dong Fang, Zhanjie Fang, Zihao Feng, Shanshan Fu, Feng Gao, Ge Gao, Hao Gao, Wen-Xing Gao, Xiao-Xuan Gao, Xin Gao, Xing-Xing Gao, Jiao Gong, Jing Gong, Yujie Gou, Siyu Gu, An-Yuan Guo, Guo Guo, Xutong Guo, Cheng Han, Di Hao, Li-Li Hao, Qin-Wen He, Shuang He, Shun-Min He, Weijuan Hu, Kaiyao Huang, Tianhao Huang, Xin-He Huang, Yuting Huang, Peilin Jia, Yaokai Jia, Chuanqi Jiang, Meiye Jiang, Shuai Jiang, Tao Jiang, Xiao-Yuan Jiang, En-Hui Jin, Wei-Wei Jin, Hai-Long Kang, Hon-Gen Kang, De-Mian Kong, Li Lan, Wenyan Lei, Chuan-Yu Li, Cui-Dan Li, Cui-Ping Li, Hao Li, Jia-Ming Li, Jiang Li, Lun Li, Pan Li, Rujiao Li, Xia Li, Yan-Yan Li, Yixue Li, Zhaohua Li, Xingyu Liao, Shi-Qiang Lin, Yihao Lin, Yun-Chao Ling, Bo Liu, Chun-Jie Liu, Dan Liu, Guanghui Liu, Lin Liu, Shulin Liu, Wangdao Liu, Xiaonan Liu, Xinxuan Liu, Yi-Yun Liu, Yu-Cheng Liu, Mingming Lu, Tianyi Lu, Hao Luo, Huaxia Luo, M. Luo, Shuai Luo, Xiao Luo, Lina Ma, Yingke Ma, Jialin Mai, Jia-Yue Meng, Xian-Wen Meng, Yuan-Guang Meng, Yuyan Meng, Wei Miao, Y. Miao, Lingbin Ni, Zhi Nie, Guangyi Niu, Xiaohui Niu, Yiwei Niu, Rong Pan, Siyu Pan, Di Peng, Jianzhen Peng, Juntian Qi, Yue Qi, Qi-Heng Qian, Yuxin Qin, H. Qu, Jian Ren, Jie Ren, Z. Sang, Kang Shang, Wen-Kang Shen, Yanting Shen, Yirong Shi, Shu-Hui Song, Tingrui Song, Tian-Han Su, Jia-Ni Sun, Yanling Sun, Yanling Sun, Yubin Sun, Bixia Tang, Dachao Tang, Qing Tang, Zhixin Tang, Dongmei Tian, Feng Tian, W. Tian, Zhi-Xi Tian, Anke Wang, Guang-Ying Wang, Guo-Liang Wang, Jian-Xin Wang, Jie Wang, Pei-Han Wang, Peng-Yu Wang, Wen-Quan Wang, Yan-Qing Wang, Yi-Bo Wang, Yi-Ming Wang, Yong-Gang Wang, Zhong-Huang Wang, Haobin Wei, Yu-Xiang Wei, Zhiyao Wei, Ding-Feng Wu, Gangao Wu, Si-Cheng Wu, Song Wu, Wanying Wu, Wenyi Wu, Zhi-Le Wu, Zhiqiang Xia, Jing-Fa Xiao, Leming Xiao, Yun Xiao, Guiyan Xie, Guiyan Xie, Jianbo Xie, Yubin Xie, Jie Xiong, Zhuang Xiong, Danyang Xu, Shu-Hua Xu, Tian-Yi Xu, Ting-Jun Xu, Yong-Biao Xue, Yu Xue, Chenghao Yan, Dechang Yang, Fang-Dian Yang, Fei Yang, Hongwei Yang, Jian Yang, Kuan Yang, Nan Yang, Qing Yang, Sen Yang, Xiao-Yu Yang, Xiao-Yu Yang, Xi-Lan Yang, Yun-Gui Yang, Wei-Dong Ye, Cai-Xia Yu, Fudong Yu, Shuhuan Yu, Chunhui Yuan, Hao Yuan, Jing-Yao Zeng, S. Zhai, Chi Zhang, Feng Zhang, Guoqing Zhang, Mochen Zhang, Peng Zhang, Qiong Zhang, Rongqin Zhang, Sisi Zhang, Wan-Yu Zhang, Wei-Qi Zhang, Weizhi Zhang, Xin Zhang, Xin-Xin Zhang, Ya-Dong Zhang, Yang Zhang, Yi-Ran Zhang, Yong E. Zhang, Yuan-Sheng Zhang, Zhang Zhang, Zhe Zhang, Dongli Zhao, Fangqing Zhao, Guo-Ping Zhao, Miao-Ying Zhao, Wei Zhao, Wen-Ming Zhao, Xuetong Zhao, Yilin Zhao, Yongbing Zhao, Zheng Zhao, Xinchang Zheng, Yu Zheng, Chenfen Zhou, Haokui Zhou, Xincheng Zhou, Xin-Yu Zhou, Yincong Zhou, Yu-Bo Zhou, Jun-Wei Zhu, Lixin Zhu, Rui-Xin Zhu, Tong-Tong Zhu, Wenting Zong, Dong Zou, Zhixiang Zuo

Nucleic Acids Research

DOI

2023

Diverse African genomes reveal selection on ancient modern human introgressions in Neanderthals

Daniel Harris, Alexander Platt, Matthew E.B. Hansen, Shaohua Fan, Michael A. McQuillan, Thomas Nyambo, Sununguko Wata Mpoloka, Gaonyadiwe George Mokone, Gurja Belay, Charles Fokunang, Alfred Kongnyu NJAMNSHI, Sarah A. Tishkoff

Current Biology

DOI

2023

A pangenome reference of 36 Chinese populations

Yang Gao, Xiaofei Yang, Hao Chen, Xinjiang Tan, Zhaoqing Yang, Lian Deng, Baonan Wang, Shuang Kong, Songyang Li, Yuhang Cui, Chang Lei, Yimin Wang, Yuwen Pan, Sen Ma, Hao Xuan Sun, Xiaohan Zhao, Yingbing Shi, Ziyi Yang, Dong‐Dong Wu, Shaoyuan Wu, Xing‐Ming Zhao, Binyin Shi, Jin Li, Zhibin Hu, Chuangxue Mao, Shaohua Fan, Qiang Gao, Juncheng Dai, Fengxiao Bu, Guanglin He, Yang Wu, Huijun Yuan, Jinchen Li, Chao Chen, Jian Yang, Chaochun Wei, Xin Jin, Xia Shen, Yan Lü, Jiayou Chu, Kai Ye, Shuhua Xu

Nature

DOI

2023

Whole-genome sequencing reveals a complex African population demographic history and signatures of local adaptation

Shaohua Fan, Jeffrey P. Spence, Yuanqing Feng, Matthew E.B. Hansen, Jonathan Terhorst, Márcia Holsbach Beltrame, Alessia Ranciaro, Jibril B Hirbo, William R. Beggs, Neil Thomas, Thomas Nyambo, Sununguko Wata Mpoloka, Gaonyadiwe George Mokone, Alfred Kongnyu NJAMNSHI, Fokunang Charles, Dawit Wolde Meskel, Gurja Belay, Yun S. Song, Sarah A. Tishkoff

Cell

DOI

2022

Signatures of Convergent Evolution and Natural Selection at the Alcohol Dehydrogenase Gene Region are Correlated with Agriculture in Ethnically Diverse Africans

Michael A. McQuillan, Alessia Ranciaro, Matthew E.B. Hansen, Shaohua Fan, William R. Beggs, Gurja Belay, Dawit Wolde Meskel, Sarah A. Tishkoff

Molecular Biology and Evolution

DOI

2022

PGG.SV: a whole-genome-sequencing-based structural variant resource and data analysis platform

Yimin Wang, Yunchao Ling, Jiao Gong, Xiaohan Zhao, Hanwen Zhou, Bo Xie, Haiyi Lou, Xinhao Zhuang, Jin Li, The Han100K Initiative, Shaohua Fan, Guoqing Zhang, Shuhua Xu

Nucleic Acids Research

DOI

2022

Comprehensive evaluation of structural variant genotyping methods based on long-read sequencing data

Xiaoke Duan, Mingpei Pan, Shaohua Fan

BMC Genomics

DOI

2019

Correction to: African evolutionary history inferred from whole genome sequence data of 44 indigenous African populations

Shaohua Fan, Derek E. Kelly, Márcia Holsbach Beltrame, Matthew E.B. Hansen, Swapan Mallick, Alessia Ranciaro, Jibril B Hirbo, Simon R. Thompson, William R. Beggs, Thomas Nyambo, Sabah A. Omar, Dawit Wolde Meskel, Gurja Belay, Alain Froment, Nick J. Patterson, David Reich, Sarah A. Tishkoff

Genome biology

DOI

2019

African evolutionary history inferred from whole genome sequence data of 44 indigenous African populations

Genome biology

DOI

2016

Are sympatrically speciating Midas cichlid fish special? Patterns of morphological and genetic variation in the closely related species Archocentrus centrarchus

Carmelo Fruciano, Paolo Franchini, Francesca Raffini, Shaohua Fan, Axel Meyer

Ecology And Evolution，Vol. 6, No. 12

DOI

2013

[Review] Shaping development through mechanical strain: the transcriptional basis of diet-induced phenotypic plasticity in a cichlid fish

Helen M. Gunter, Shaohua Fan, Fan Xiong, Paolo Franchini, Carmelo Fruciano, Axel Meyer

Molecular Ecology，Vol. 220, No. 170

DOI

2013

The evolutionary history of Xiphophorus fish and their sexually selected sword: a genome-wide approach using restriction site-associated DNA sequencing

Julia C. Jones, Shaohua Fan, Paolo Franchini, Manfred Schartl, Axel Meyer

Molecular Ecology，Vol. 22, No. 110

DOI

2008

小鼠ERβ基因片段的克隆及其在胚胎发育中的表达

张子峰，樊少华，陆军，吴冬梅，单群，胡斌，李飞，郑元林

《遗传》

2008

整体原位杂交检测ERα基因在小鼠胚胎发育中的表达

张子峰，樊少华，陆军，吴冬梅，单群，胡斌，郑元林

《动物学杂志》

预印本

2025

A Long-read based Haplotype Panel Enhances Imputation and Discovery of Functional Small and Structural Variants

Shaohua Fan, Tingting Gong, Yulu Zhou, Junfan Zhao, Yechao Huang, Jiao Gong, Jinxi Li, Qianqian Peng, Huidan Chang, Liyun Yuan, Guoqing Zhang, Sijia Wang, Jin Li

Research Square

DOI

2024

Comprehensive structural variant haplotype panel of 943 Han Chinese from long-read whole-genome sequencing

Tingting Gong, Yulu Zhou, Yechao Huang, Junfan Zhao, Jiao Gong, Jinxi Li, Qianqian Peng, Sijia Wang, Jin Li, Shaohua Fan

Research Square

DOI

2022

Characterizing the genetic polymorphisms in 370 challenging medically relevant genes using long-read sequencing data from 41 human individuals among 19 global populations

Yanfeng Ji, Jiao Gong, Fritz Joachim Sedlazeck, Shaohua Fan

bioRxiv (Cold Spring Harbor Laboratory)

DOI

樊少华

精选作品

期刊论文

Anthropometric and cardio-metabolic trait variation and genetic associations in sub-Saharan Africa.

An East Asian blood eQTL meta-analysis highlights ancestry-matched eQTL resources for complex-trait genetics

Long-read sequencing of 945 Han individuals identifies structural variants associated with phenotypic diversity and disease susceptibility

An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis

Early to Middle Pleistocene transition shapes the evolution of human-specific mutations associated with height and basal metabolic rate

Integrative functional genomic analyses identify genetic variants influencing skin pigmentation in Africans

Unveiling novel genetic variants in 370 challenging medically relevant genes using the long read sequencing data of 41 samples from 19 global populations

Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2024

Diverse African genomes reveal selection on ancient modern human introgressions in Neanderthals

A pangenome reference of 36 Chinese populations

Whole-genome sequencing reveals a complex African population demographic history and signatures of local adaptation

Signatures of Convergent Evolution and Natural Selection at the Alcohol Dehydrogenase Gene Region are Correlated with Agriculture in Ethnically Diverse Africans

PGG.SV: a whole-genome-sequencing-based structural variant resource and data analysis platform

Comprehensive evaluation of structural variant genotyping methods based on long-read sequencing data

Correction to: African evolutionary history inferred from whole genome sequence data of 44 indigenous African populations

African evolutionary history inferred from whole genome sequence data of 44 indigenous African populations

Are sympatrically speciating Midas cichlid fish special? Patterns of morphological and genetic variation in the closely related species Archocentrus centrarchus

[Review] Shaping development through mechanical strain: the transcriptional basis of diet-induced phenotypic plasticity in a cichlid fish

The evolutionary history of Xiphophorus fish and their sexually selected sword: a genome-wide approach using restriction site-associated DNA sequencing

小鼠ERβ基因片段的克隆及其在胚胎发育中的表达

整体原位杂交检测ERα基因在小鼠胚胎发育中的表达

预印本

A Long-read based Haplotype Panel Enhances Imputation and Discovery of Functional Small and Structural Variants

Comprehensive structural variant haplotype panel of 943 Han Chinese from long-read whole-genome sequencing

Characterizing the genetic polymorphisms in 370 challenging medically relevant genes using long-read sequencing data from 41 human individuals among 19 global populations

研究方向