百晓学者学者目录

孙磊

副教授、副研究员、助理教授、教授、研究员、讲师,武汉大学

精选作品

期刊论文

2026

Lactobacillus rhamnosus CCFM1131 Alleviates Hyperuricemia through Modulation of Gut Microbiota and Metabolites: A Randomized, Double-Blind, Placebo-Controlled Trial

Ding-Xu Zhu, Qian Jiang, Lei Sun, Xuhua Mao, Feng Hang, Q. Zhai, Wei Chen, Gang Wang, Qian-Yun Deng, Xiaohong Wu

Food Science and Human Wellness

2026

A multi-strain probiotic formulation alleviates chronic constipation in middle-aged and older adults: A randomized, double-blind, placebo-controlled trial.

Rui Xiao, Yeping He, Xuhua Mao, Lei Sun, Lanxi Ao, Lin-Lin Wang, Q. Zhai, Jian-Xin Zhao, Wei Chen, Gang Wang, Jian Guo

Clinical Nutrition

2026

Bifidobacterium breve CCFM1179 Modulates Gut Microbiota and Improves Mild Cognitive Impairment: A Randomized, Double-Blind, Placebo-Controlled Trial

Yanyan Che, Xiaohong Wu, Lei Sun, Zhihua Zhang, Xuhua Mao, Feng Hang, Wenwei Lu, Q. Zhai, Wei Chen, Gang Wang, Jie Li

Food Science and Human Wellness

2026

Pasteurized Akkermansia muciniphila AH39 alleviates high-fat diet-induced obesity by modulating the gut microbiota-bile acid metabolism-FXR pathway

Si-Han Kuang, Jia-Le Wang, Tian Jiang, Lei Sun, Lin-Lin Wang, Pei-Jun Tian, Q. Zhai, Jian-Xin Zhao, Gang Wang, Zhi Wang

Food Bioscience

2026

Isoform usage dynamics in metabolic adaptation

Yadanar Than Naing, Xianli Ju, Jia Li, Lei Sun

Trends in Endocrinology and Metabolism

2025

GEPREP: A comprehensive data atlas of RNA-seq-based gene expression profiles of exercise responses

Lei Sun, Jinwen Luan, Jinbiao Wang, Xiaoli Li, Wenqian Zhang, Xiaohui Ji, Longhua Liu, Ru Wang, Bingxiang Xu

Journal Of Sport And Health Science,Vol. 14

2025

The human gut microbiota and uric acid metabolism: genes, metabolites, and diet

Lei Sun, Min Zhang, Jian-Xin Zhao, Wei Chen, Gang Wang

Critical reviews in food science and nutrition

2025

Electrostatically sprayed alginate-carboxymethyl chitosan microgel for colon-targeted melatonin delivery ameliorates ulcerative colitis

Lei Sun, Jian-Xin Zhao, Wei Chen, Gang Wang

Food Bioscience

2025

Artificial intelligence in metabolic research

Jens Juul Holst, Camilla Charlotte Scheele, Philipp E. Scherer, Weiping Jia, Eran Segal, Nikolai Slavov, Ruth J. F. Loos, Golnaz Vahedi, Lei Sun, M. Madan Babu, Melissa D. McCradden, Peter G. Jacobs

Nature Metabolism

2025

Isoform usage as a distinct regulatory layer driving nutrient-responsive metabolic adaptation

Jia Li, Chaoqun Cai, Wei Wen Teo, Kai Shin Chin, Yadanar Than Naing, Shengren Song, Franklin Nelson, Li Qiang, Dan Xu, Lei Sun

Cell Metabolism

2024

Enhancing rutin accumulation in Tartary buckwheat through a novel flavonoid transporter protein FtABCC2.

Jiali Zhao, Lei Sun, Lei Wang, Kai Xiang, Yao Xiao, Cheng-Lei Li, Hua-La Wu, Hai-Xia Zhao, Qi Wu

International Journal of Biological Macromolecules

2024

Limosilactobacillus reuteriCCFM1132 Modulates Gut Microbiota and Alleviates Hyperuricemia: A Randomized, Double-Blind, Placebo-Controlled Trial

Lei Sun, Yang Cao, Feng Hang, Dongbo Yuan, Honglun Wang, Jian-Xin Zhao, Gang Wang, Guo-Hong Qiao, Li-Yun Wang

Food Science and Human Wellness

2021

The Natural Antimicrobial trans-Cinnamaldehyde Interferes with UDP-N-Acetylglucosamine Biosynthesis and Cell Wall Homeostasis in Listeria monocytogenes

Lei Sun, G. Rogiers, C. Michiels

Foods

2021

Characterization of three glutamate decarboxylases from Bacillus spp. for efficient γ-aminobutyric acid production

Lei Sun, Yingguo Bai, Xiu Zhang, Cheng Zhou, Jie Zhang, Xiao-Yun Su, Hui-Ying Luo, B. Yao, Yuan Wang, T. Tu

Microbial Cell Factories

2021

Community Structure and Function of Epiphytic Bacteria Associated With Myriophyllum spicatum in Baiyangdian Lake, China

Lei Sun, Jia-Shuo Wang, Yang-huan Wu, Tianyu Gao, Cunqi Liu

Frontiers in Microbiology

2021

AsnB Mediates Amidation of Meso-Diaminopimelic Acid Residues in the Peptidoglycan of Listeria monocytogenes and Affects Bacterial Surface Properties and Host Cell Invasion

Lei Sun, G. Rogiers, P. Courtin, M. Chapot-Chartier, H. Bierne, C. Michiels

Frontiers in Microbiology

2020

长链非编码RNA B3GALT5-AS1靶向miR-361-3p调节大鼠胰腺腺泡细胞增殖及凋亡的分子机制

孙磊,万莎莎,王超君,陈珊珊

《中国细胞生物学学报》

2020

An integrative multi-omics approach points to membrane composition as a key factor in E. coli persistence

Silvia J. Cañas-Duarte, Lei Sun, M. I. Perez-Lopez, C. Herrfurth, Lina M. Contreras, I. Feussner, Chad Leidy, J. Paulsson, D. Riaño-Pachón, J. Pedraza, S. Restrepo

bioRxiv

2019

Paenibacillus cymbidii sp. nov., isolated from Cymbidium goeringii roots.

Lei Sun, Panpan Wang, Dongfang Zhao, Jia-Shuo Wang, Qiji Wu, Lin Liu, Zhitang Lyu

International Journal of Systematic and Evolutionary Microbiology

2019

Screening, identification and characterization of a pyridine degrading bacterium Paracoccus pantotrophus B21-3

Lei Sun, Tong-Tong Song, Jia-Shuo Wang, Cunqi Liu

2018

Manipulation of two regulatory genes for efficient production of chromomycins in Streptomyces reseiscleroticus

Lei Sun, Jia Zeng, Peiwu Cui, Wei Wang, Da-Yu Yu, J. Zhan

Journal of Biological Engineering

2018

An efficient process for co-production of γ-aminobutyric acid and probiotic Bacillus subtilis cells

Hongbo Wang, Jinge Huang, Lei Sun, Fu-Chao Xu, Wei Zhang, J. Zhan

Food Science and Biotechnology

2018

Identification and heterologous reconstitution of a 5-alk(en)ylresorcinol synthase from endophytic fungus Shiraia sp. Slf14

Hui Yan, Lei Sun, Jinge Huang, Yixing Qiu, Fu-Chao Xu, R. Yan, Du Zhu, Wen Wang, J. Zhan

Journal of Microbiology

2018

A novel homodimer laccase from Cerrena unicolor BBP6: Purification, characterization, and potential in dye decolorization and denim bleaching

Ji Zhang, Lei Sun, Hao Zhang, Shufang Wang, Xiao-Yu Zhang, Anli Geng

PLoS ONE

2018

The Temporal Expression Dynamics of Antibiotic Resistances

Lei Sun

2017

Rhizobium oryziradicis sp. nov., isolated from rice roots.

Juanjuan Zhao, Jun Zhang, Lei Sun, Rui-Jie Zhang, Cai-Wen Zhang, Hua-Qun Yin, Xiao-Xia Zhang

International Journal of Systematic and Evolutionary Microbiology

2017

Investigation and Engineering of Polyketide Biosynthetic Pathways

Lei Sun

2017

Investigation of T7 exonuclease dependent one-step cloning

J. Qiu, Manman Zhao, Ye Wei, Lilan Cui, Qing-Yi Zhang, Lei Sun, D. Lu

2016

Characterization of Three Tailoring Enzymes in Dutomycin Biosynthesis and Generation of a Potent Antibacterial Analogue.

Lei Sun, Siyuan Wang, Shuwei Zhang, L. Shao, Qian Zhang, C. Skidmore, C. Chang, Da-Yu Yu, J. Zhan

ACS Chemical Biology

2016

Identification of a type III polyketide synthase involved in the biosynthesis of spirolaxine

Lei Sun, Siyuan Wang, Shuwei Zhang, Da-Yu Yu, Yu-Hui Qin, Hui-Yong Huang, Wei Wang, J. Zhan

Applied Microbiology and Biotechnology

2015

Screening , identification and fermentation optimization of xylanase - producing endophytic bacteria from Cymbidium faberi Roots

Lei Sun

2015

Genetic diversity of culturable endophytic bacteria in the roots of wild and greenhouse Cymbidium faberi

Pan-Pan Wang, Yong-Xiu Wu, Tong-Tong Song, Chun-Ling Ma, Wen Zhao, Ying Wang, Lei Sun

2014

Rhizobium rhizoryzae sp. nov., isolated from rice roots.

Xiao-Xia Zhang, Xue Tang, Rizwan Ali Sheirdil, Lei Sun, Xiao-Tong Ma

International Journal of Systematic and Evolutionary Microbiology

2014

Effects of exogenous nutrients on polyketide biosynthesis in Escherichia coli

Lei Sun, Jia Zeng, Shuwei Zhang, Tyler Gladwin, J. Zhan

Applied Microbiology and Biotechnology

2014

Activating the production of antitumor chromomycins in Streptomyces roseiscleroticus

Lei Sun

2014

Characterization of a full-length infectious clone of bovine foamy virus 3026

Tie-Jun Bing, Hong Yu, Yue Li, Lei Sun, Juan Tan, Yun-Qi Geng, W. Qiao

Virologica Sinica

2013

RfaH Suppresses Small RNA MicA Inhibition of fimB Expression in Escherichia coli K-12

Alexandra Moores, Saranna Chipper-Keating, Lei Sun, Gareth McVicker, Lynn Wales, Krishna Gashi, I. Blomfield

Journal of Bacteriology

2013

Isolation and characterization of a novel cinosulfuron degrading Kurthia sp. from a methanogenic microbial consortium.

Zhi-Yong Ruan, Shan Zhou, Sheng-Hua Jiang, Lei Sun, Yi Zhai, Yanwei Wang, Chao Chen, Bin Zhao

Bioresource Technology

2013

Chitinophaga cymbidii sp. nov., isolated from Cymbidium goeringii roots.

Lubin Li, Lei Sun, Nan Shi, Lin Liu, Huijuan Guo, Ai-Fang Xu, Xiao-Xia Zhang, N. Yao

International Journal of Systematic and Evolutionary Microbiology

2012

Diversity of DMSP transport in marine bacteria, revealed by genetic analyses

Lei Sun, A. Curson, Jonathan D. Todd, A. Johnston

Biogeochemistry

2012

Identification of Antagonistic Endophyte Bacterial Strain gt19-1 from Cymbidium goeringii and Its Biocontrol Effect on Gloeosprium piperatum

Lei Sun

2011

SLYA ACTIVATES FIMB EXPRESSION AND TYPE 1 FIMBRIATION IN ESCHERICHIA COLI K-12 *

Gareth McVicker, Lei Sun, Baljinder K. Sohanpal, Krishna Gashi, R. A. Williamson, J. Plumbridge, I. Blomfield

2011

Rhizobium pseudoryzae sp. nov., isolated from the rhizosphere of rice.

Xiao-Xia Zhang, Lei Sun, Xiao-Tong Ma, X. Sui, Rui-Bo Jiang

International Journal of Systematic and Evolutionary Microbiology

2011

[Diversity of siderophore-producing endophytic bacteria of Cymbidium goeringii roots].

Lei Sun, Hong Shao, Lin Liu, Rui-Ying Zhang, Li-Hua Zhao, Lubin Li, N. Yao

Wei sheng wu xue bao = Acta microbiologica Sinica

2011

Increased Susceptibility to DNA Virus Infection in Mice with a GCN2 Mutation

Sungyong Won, Celine Eidenschenk, Carrie N. Arnold, O. Siggs, Lei Sun, Katharina Brandl, T. Mullen, G. Nemerow, E. Moresco, B. Beutler

Journal of Virology

2011

Characterization of a bifunctional β-lactamase/ribonuclease and its interaction with a chaperone-like protein in the pathogen Mycobacterium tuberculosis H37Rv

Lei Sun, Lei Zhang, Hua Zhang, Zheng-Guo He

Biochemistry (Moscow)

2010

Characterization of the Duck Plague Virus UL35 Gene

Mingsheng Cai, A. Cheng, Ming-Shu Wang, Wan-Ping Chen, Xian Zhang, Shang-Xi Zheng, Yang Pu, Kunpeng Lou, Yao Zhang, Lei Sun, Lu-lu Wang, De-Kang Zhu, Qi-Hui Luo, Xiao-Yue Chen

Intervirology

2010

Molecular dissection of bacterial acrylate catabolism--unexpected links with dimethylsulfoniopropionate catabolism and dimethyl sulfide production.

Jonathan D. Todd, A. Curson, Nefeli Nikolaidou-Katsaraidou, C. Brearley, N. Watmough, Y. Chan, P. B. Bulman Page, Lei Sun, A. Johnston

Environmental Microbiology

2009

Bacillus beijingensis sp. nov. and Bacillus ginsengi sp. nov., isolated from ginseng root.

Fubin Qiu, Xiao-Xia Zhang, Lin Liu, Lei Sun, P. Schumann, Wei-Bo Song

International Journal of Systematic and Evolutionary Microbiology

2009

Development of recombinant fowlpox virus coexpressing HA and NA gene from subtype H5N1 of avain influenza virus and it's protective efficacy in commercial chickens of high maternal antibodies

Su-Juan Chen, Lei Sun, Huo-Ying Shi, Wu-Jie Liu, D. Peng, Xiu-Fan Liu

2008

Rheinheimera tangshanensis sp. nov., a rice root-associated bacterium.

Xiao-Xia Zhang, Lei Sun, Fubin Qiu, R. McLean, Rui-Bo Jiang, Wei-Bo Song

International Journal of Systematic and Evolutionary Microbiology

2008

Isolation and identification of an alkaliphilic Bacillus flexus XJU-3 and analysis of its alkaline amylase.

Jian Zhao, Xiao-Jun Lan, Jun Su, Lei Sun, Erkin Rahman

Wei sheng wu xue bao = Acta microbiologica Sinica

2008

一株碱性淀粉酶产生菌Bacillus flexus XJU-3的分离鉴定及酶学特性分析

Jian Zhao, Xiao-Jun Lan, Jun Su, Lei Sun, 艾尔肯 热合曼

2008

Molecular diversity of bacterial production of the climate-changing gas, dimethyl sulphide, a molecule that impinges on local and global symbioses.

A. Johnston, Jonathan D. Todd, Lei Sun, M. N. Nikolaidou-Katsaridou, A. Curson, Rachel Rogers

Journal of Experimental Botany

2008

Design and Evaluation of a 16S rRNA Gene-based Oligonucleotide Micrroarray for Identification of Plant Associated Beneficial Bacteria (PABB)

Zhengqiu Cai, Lei Sun, Jigang Han, M. Yan, Wei Song, Zhao-Biao Guo, Yu Wang, Rui-Fu Yang

International Conference on BioMedical Engineering and Informatics

2007

Generation of an attenuated H5N1 avian influenza virus vaccine with all eight genes from avian viruses.

Huo-Ying Shi, Xiu-Fang Liu, Xiao-Rong Zhang, Su-Juan Chen, Lei Sun, Jian-Hong Lu

Vaccine

2007

Characterization of a Putative Methyltranferase Gene and Its Expression in Tetrahymena

Lei Sun

2007

Leifsonia ginsengi sp. nov., isolated from ginseng root.

Fubin Qiu, Ying Huang, Lei Sun, Xiao-Xia Zhang, Zhiheng Liu, Wei-Bo Song

International Journal of Systematic and Evolutionary Microbiology

2007

Dyadobacter beijingensis sp. nov., isolated from the rhizosphere of turf grasses in China.

Zhi Dong, Xiao-Yu Guo, Xiao-Xia Zhang, Fubin Qiu, Lei Sun, H. Gong, Fei-Yun Zhang

International Journal of Systematic and Evolutionary Microbiology

2007

[Prokaryotic expression of pilA gene of type I pilus of enteropathogenic Escherichia coli isolated from ducks and the immunoprotection effect of recombinant expression protein challenged with virulent strains].

A. Cheng, Xiao-Na Yu, Ming-Shu Wang, De-Kang Zhu, Ling Li, Lei Sun, Xiao-Yue Chen

Sheng wu gong cheng xue bao = Chinese journal of biotechnology

2006

Determination of the DNA G+C mol% in Bacillus claussi Strains by Reversed-Phase High Performance Liquid Chromatography

Lei Sun

2006

[Recombinant fowlpox virus coexpressing HA and NA gene from subtype H5N1 of avian influenza virus and its protective efficacy].

Su-Juan Chen, Lei Sun, Wu-Jie Liu, Xue Sun, Xiu-Fan Liu

Wei sheng wu xue bao = Acta microbiologica Sinica

2005

利用8质粒系统拯救A/Chicken/Shanghai/F/98(H9N2)株禽流感病毒

Huo-Ying Shi, Jian-Hong Lu, Su-Juan Chen, Lei Sun, Xiu-Fan Liu, Yu-Liang Liu

2005

[Generation of A/Chicken/Shanghai/F/98 (H9N2) avian influenza virus from eight plasmids].

Huo-Ying Shi, Jian-Hong Lu, Su-Juan Chen, Lei Sun, Xiu-Fan Liu

Wei sheng wu xue bao = Acta microbiologica Sinica

2005

Characterization of a novel plant growth-promoting bacteria strain Delftia tsuruhatensis HR4 both as a diazotroph and a potential biocontrol agent against various plant pathogens.

Jigang Han, Lei Sun, Xiuzhu Dong, Zhengqiu Cai, Xiaolu Sun, Hai-Lian Yang, Yun-Shan Wang, Wei-Bo Song

Systematic and Applied Microbiology

2005

[Influence of nonessential region on protective efficacy of recombinant fowlpox viruses].

Lei Sun, Wu-Jie Liu, Su-Juan Chen, Huo-Ying Shi, Xiu-Fan Liu

Wei sheng wu xue bao = Acta microbiologica Sinica

2005

Recombinant Fowlpox Virus Coexpressing HA from Subtype H5N1 and Subtype H9N2 of Avain Influenza Virus and Its Protective Efficacy

Su-Juan Chen, Huo-Ying Shi, Lei Sun, Xiu-Fan Liu

2002

Cloning and characterization of a gene encoding phagerelated tail protein (PrTP) of endosymbiont Wolbachia

L. Kang, Lei Sun, Hong Yu, Wei-Guo Zhou, Shou-Yuan Zhao, Chang-ben Li

2002

Cloning and Characterization of a Gene Encoding Glutathione-regulated Potassium-efflux System Protein KefKL from the Endosymbiont Wolbachia

L. Kang, Huanhu Zhu, Q. Cheng, Wei-Guo Zhou, Lei Sun, Li-Jun Cai, Xi-Zhi Ma, Chunmei Chen, Shou-Yuan Zhao, Chang-ben Li

DNA Sequence

1996

A cloning and partial nucleotide sequencing of the amplified E gene fragment of dengue-2 virus

Man Yu, E. Qin, Peiying Yang, Lei Sun, Pin-Fang Xu, B. Si, G. Yan

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