吴亚林｜厦门大学｜学者主页

百晓学者学者目录

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期刊论文

2026

ATF4 Activation Promotes All-trans-Retinal-Driven Retinopathies in Mice

Kunhuan Yang, Chaofeng Yu, Danxue He, Lei Tao, Bo Yang, Yuling Chen, Chen Jingmeng, Yalin Wu

Antioxidants

DOI

2026

Exendin-4 averts all-trans-retinal-driven damage to photoreceptors and the retina via the GLP-1R/PKA/CREB1 signaling axis

Beiting He, Yuling Chen, Peixin Cai, Ruitong Xi, Xiaoqing Shen, Shuting Guo, Jun Chen, Shiying Li, Yalin Wu

Cellular & Molecular Biology Letters

DOI

2025

Exposure of A2E to blue light promotes ferroptosis in the retinal pigment epithelium

Bo Yang, Kunhuan Yang, Yuling Chen, Qingjian Li, Jingmeng Chen, Shiying Li, Yalin Wu

Cellular & Molecular Biology Letters

DOI

2025

Gene editing of JNK alleviates sodium iodate-induced retinal degeneration in mice

Lei Tao, Danxue He, Yuling Chen, Peixin Cai, Kunhuan Yang, Jianfeng Wu, Chunyan Liao, Jingmeng Chen, Yalin Wu

Life Sciences

DOI

2025

Activation of GSDME by all- trans -retinal increases sensitivity to photoreceptor ferroptosis

Bo Yang, Kunhuan Yang, Yuling Chen, Ruitong Xi, Jiahuai Han, Shiying Li, Jingmeng Chen, Yalin Wu

International Journal of Biological Sciences

DOI

2025

Ferrostatin-1, a ferroptosis inhibitor, mitigates all-trans-retinal-induced retinal pigment epithelium degeneration in mice

Xiaoqing Shen, Yuling Chen, Beiting He, Ruitong Xi, Jingmeng Chen, Yalin Wu

Journal of Translational Medicine

DOI

2025

Long-term senolytic therapy with Dasatinib and Quercetin alleviates lipofuscin-dependent retinal degeneration in mice

Bo Yang, Kunhuan Yang, Ruitong Xi, Shiying Li, Jingmeng Chen, Yalin Wu

Redox Biology

DOI

2024

Quercetin Alleviates All-Trans-Retinal-Induced Photoreceptor Apoptosis and Retinal Degeneration by Inhibiting the ER Stress-Related PERK Signaling

Bo Yang, Kunhuan Yang, Ruitong Xi, Jingmeng Chen, Yalin Wu

International Journal of Molecular Sciences

DOI

2024

Transferrin ameliorates retinal degeneration by mediating the dimerization of all-trans-retinal

Lei Tao, Danxue He, Yuling Chen, Kunhuan Yang, Beiting He, Peixin Cai, Binxiang Cai, Chunyan Liao, Zuguo Liu, Shiying Li, Jingmeng Chen, Yalin Wu

Journal of Biological Chemistry

DOI

2024

Inhibition of JNK signaling attenuates photoreceptor ferroptosis caused by all-trans-retinal

Bo Yang, Kunhuan Yang, Ruitong Xi, Shiying Li, Jingmeng Chen, Yalin Wu

Free Radical Biology and Medicine

DOI

2024

Crocin Protects the 661W Murine Photoreceptor Cell Line against the Toxic Effects of All-Trans-Retinal

Bo Yang, Kunhuan Yang, Jingmeng Chen, Yalin Wu

International Journal of Molecular Sciences

DOI

2023

eIF2α incites photoreceptor cell and retina damage by all-trans-retinal

Danxue He, Lei Tao, Binxiang Cai, Xiangjun Chen, Yan Wang, Shiying Li, Chunyan Liao, Yuling Chen, Jingmeng Chen, Zuguo Liu, Yalin Wu

Journal of Biological Chemistry

DOI

2023

Effect of palmitoylethanolamide on degeneration of a human-derived retinal pigment epithelial cell induced by all-trans retinal

Yun Han, Danxue He, Chaofeng Yu, Lei Tao, Chun-Yan Liao, Binxiang Cai, Zuguo Liu, Yan Qiu, Yalin Wu

International Journal of Ophthalmology

DOI

2022

Induction of ferroptosis by HO-1 contributes to retinal degeneration in mice with defective clearance of all-trans-retinal

Chao Chen, Kunhuan Yang, Danxue He, Bo Yang, Lei Tao, Jingmeng Chen, Yalin Wu

Free Radical Biology and Medicine

DOI

2022

Cyanidin-3-glucoside improves the barrier function of retinal pigment epithelium cells by attenuating endoplasmic reticulum stress-induced apoptosis

Wenting Peng, Yalin Wu, Zhenzhen Peng, Wentao Qi, Tingting Liu, Bo Yang, Danxue He, Yixiang Liu, Yong Wang

Food Research International

DOI

2021

Gasdermin E mediates photoreceptor damage by all-trans-retinal in the mouse retina

Binxiang Cai, Chunyan Liao, Danxue He, Jingmeng Chen, Jiahuai Han, Jiaying Lu, Kaiqi Qin, Wenxu Liang, Xiaoling Wu, Zuguo Liu, Yalin Wu

Journal of Biological Chemistry

DOI

2021

Repressing c-Jun N-terminal kinase signaling mitigates retinal pigment epithelium degeneration in mice with failure to clear all-trans-retinal

Lei Tao, Danxue He, Chunyan Liao, Binxiang Cai, Chao Chen, Yan Wang, Jingmeng Chen, Zuguo Liu, Yalin Wu

Experimental Eye Research

DOI

2021

Ferroptosis drives photoreceptor degeneration in mice with defects in all-trans-retinal clearance

Chao Chen, Jingmeng Chen, Yan Wang, Zuguo Liu, Yalin Wu

Journal of Biological Chemistry

DOI

2020

IL‐1/IL‐1R signaling induced by all‐trans‐retinal contributes to complement alternative pathway activation in retinal pigment epithelium

Xinxuan Cheng, Danxue He, Chunyan Liao, Sijie Lin, Liying Tang, Yuanliang Wang, Jiaoyue Hu, Wei Shan Li, Zuguo Liu, Yalin Wu, Yi Liao

Journal of Cellular Physiology

DOI

2020

Activation of JNK signaling promotes all-trans-retinal–induced photoreceptor apoptosis in mice

Chunyan Liao, Binxiang Cai, Yufeng Feng, Jingmeng Chen, Yiping Wu, Yiping Wu, Jingbin Zhuang, Zuguo Liu, Yalin Wu, Yalin Wu

Journal of Biological Chemistry

DOI

2019

HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration

Shuo Sun, Bincui Cai, Yao Li, Wenqi Su, Xu-Zheng Zhao, Boteng Gong, Zhiqing Li, Xiaomin Zhang, Yalin Wu, Chao Chen, Stephen H. Tsang, Jin Yang, Xiaorong Li

Aging

DOI

2019

All-trans-retinoic acid generation is an antidotal clearance pathway for all-trans-retinal in the retina

Qingqing Xia, Lingmin Zhang, Yingying Zhou, Yalin Wu, Jie Li

Journal of Zhejiang University SCIENCE B

DOI

2019

NLRP3 inflammasome activation by all-trans-retinaldehyde underlies the degeneration of retinal pigment epithelial cells

Yi Liao, Yalin Wu

Investigative Ophthalmology & Visual Science

2019

Retinal Pigment Epithelium Cell Death Is Associated With NLRP3 Inflammasome Activation by All- trans Retinal

Yi Liao, Houjian Zhang, Danxue He, Yan Wang, Binxiang Cai, Jingmeng Chen, Jian‐xing Ma, Zuguo Liu, Yalin Wu

Investigative Ophthalmology & Visual Science

DOI

2018

Conversion of all-trans-retinal into all-trans-retinal dimer reflects an alternative metabolic/antidotal pathway of all-trans-retinal in the retina

Zhan Gao, Yi Liao, Chao Chen, Chunyan Liao, Danxue He, Jingmeng Chen, Jian‐xing Ma, Zuguo Liu, Yalin Wu

Journal of Biological Chemistry

DOI

2018

All-trans-retinaldehyde participates in complement activation in retinal pigment epithelium by downregulating complement regulatory proteins

Yi Liao, Yalin Wu

Investigative Ophthalmology & Visual Science

2018

The Visual Chromophore All-Trans-Retinaldehyde in Retinal Pigment Epithelial Cells: An Alternative Metabolic Pathway

Yalin Wu

Investigative Ophthalmology & Visual Science

2017

Aberrant Buildup of All- Trans -Retinal Dimer, a Nonpyridinium Bisretinoid Lipofuscin Fluorophore, Contributes to the Degeneration of the Retinal Pigment Epithelium

Junli Zhao, Yi Liao, Jingmeng Chen, Xinran Dong, Zhan Gao, Houjian Zhang, Xiaodan Wu, Zuguo Liu, Yalin Wu

Investigative Ophthalmology & Visual Science

DOI

2016

All-trans-retinal dimer formation alleviates the cytotoxicity of all-trans-retinal in human retinal pigment epithelial cells

Jie Li, Yanli Zhang, Xianhui Cai, Qingqing Xia, Jingmeng Chen, Yi Liao, Zuguo Liu, Yalin Wu

Toxicology

DOI

2016

Potential Therapeutic Agents Against Retinal Diseases Caused by Aberrant Metabolism of Retinoids

Xin Liu, Jingmeng Chen, Zhe Liu, Jie Li, Ke Yao, Yalin Wu

Investigative Ophthalmology & Visual Science

DOI

2015

Protective effect of autophagy on human retinal pigment epithelial cells against lipofuscin fluorophore A2E: implications for age-related macular degeneration

J Zhang, Yihan Bai, Lan Ji Huang, Yun Qi, Qingbi Zhang, Simin Li, Yalin Wu, Xiting Li

Cell Death and Disease

DOI

预印本

2026

RIPK3 suppresses photoreceptor degeneration in a Stargardt disease mouse model

Feng Wen, Xiying Zhai, Wanling He, Yaqiong Yang, Liying Tang, 张月华, Małgorzata Rôżanowska, Xinxuan Cheng, Jiani Li, Jintao Shi, Wenhua Li, Chunxia Chen, Li Qian, Zhaoqiang Zhang, Yalin Wu, Mouxin Zhang, Jianfeng Wu, Yi Liao

bioRxiv (Cold Spring Harbor Laboratory)

DOI

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