卢晓｜南方医科大学｜学者主页

2023

Mannan-binding lectin ameliorates renal fibrosis by suppressing macrophage-to-myofibroblast transition

Li Xu, Honglian Jiang, Jingwen Xie, Qishan Xu, Jia Zhou, Xiao Lu, Mingyong Wang, Lijun Dong, Daming Zuo

Heliyon

2022

MBL Binding with AhR Controls Th17 Immunity in Silicosis-Associated Lung Inflammation and Fibrosis

Yunzhi Liu, Na Zhao, Qishan Xu, Fan Deng, Ping Wang, Lijun Dong, Xiao Lu, Lihua Xia, Mingyong Wang, Zhengliang Chen, Jia Zhou, Daming Zuo

Journal of Inflammation Research

DOI

2022

Mannan-Binding Lectin Reduces Epithelial-Mesenchymal Transition in Pulmonary Fibrosis via Inactivating the Store-Operated Calcium Entry Machinery

Yunzhi Liu, Xianghuan Xie, Ping Wang, Jialiang Luo, Yu Chen, Qishan Xu, Jia Zhou, Xiao Lu, Jianbo Zhao, Zhengliang Chen, Daming Zuo

Journal of Innate Immunity

DOI

2022

Mannan-Binding Lectin via Interaction With Cell Surface Calreticulin Promotes Senescence of Activated Hepatic Stellate Cells to Limit Liver Fibrosis Progression

Jialiang Luo, Lei Li, Bo Yoon Chang, Zhengyumeng Zhu, Fan Deng, Mengyao Hu, Yu Yu, Xiao Lu, Zhengliang Chen, Daming Zuo, Jia Zhou

Cellular and Molecular Gastroenterology and Hepatology

DOI

2022

Mannan-Binding Lectin Deficiency Limits Inflammation-induced Myeloid-Derived Suppressor Cells Expansion via Modulating Tumor Necrosis Factor Alpha-triggered Apoptosis

Lijun Dong, Honglian Jiang, Kai Chen, Jingwen Xie, Qing An, Fan Deng, Zhengyang Sun, Yunzhi Liu, Jia Zhou, Liyun Zhang, Xiao Lu, Mingyong Wang, Zhengliang Chen, Xiaoming Zou, Daming Zuo

International Journal of Biological Sciences

DOI

2021

Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release

Yu Chen, Mengyao Hu, Fan Deng, Ping Wang, Jingmin Lin, Zhuojun Zheng, Yunzhi Liu, Lijun Dong, Xiao Lu, Zhengliang Chen, Jia Zhou, Daming Zuo

Cell Calcium

DOI

2019

Mannan-Binding Lectin Regulates Inflammatory Cytokine Production, Proliferation, and Cytotoxicity of Human Peripheral Natural Killer Cells

Jia Zhou, Mengyao Hu, Jie Li, Yan Liu, Jialiang Luo, Liyun Zhang, Xiao Lu, Daming Zuo, Zhengliang Chen

Mediators of Inflammation

DOI

2019

Mannan‐binding lectin attenuates acetaminophen‐induced hepatotoxicity by regulating CYP2E1 expression via ROS‐dependent JNK/SP1 pathway

Huifang Li, Yan Liu, Junru Li, Yunzhi Liu, Lijun Dong, Yue Yin, Yu Yu, Jia Zhou, Liyun Zhang, Xiao Lu, Zhengliang Chen, Daming Zuo

European Journal of Immunology

DOI

2018

Mannan-binding lectin deficiency exacerbates sterile liver injury in mice through enhancing hepatic neutrophil recruitment

Jia Zhou, Junru Li, Yu Yu, Yan Liu, Huifang Li, Yunzhi Liu, Jun Wang, Liyun Zhang, Xiao Lu, Zhengliang Chen, Daming Zuo

Journal of Leukocyte Biology

DOI

2018

Mannan-binding lectin suppresses growth of hepatocellular carcinoma by regulating hepatic stellate cell activation via the ERK/COX-2/PGE2 pathway

Junru Li, Huifang Li, Yu Yu, Yan Liu, Yunzhi Liu, Qiang Ma, Liyun Zhang, Xiao Lu, Xiangyang Wang, Zhengliang Chen, Daming Zuo, Jia Zhou

OncoImmunology

DOI

2017

肝细胞肝癌患者血浆中甘露聚糖结合凝集素和甘露聚糖结合凝集素相关丝氨酸蛋白酶-2的表达水平

李捷，朱玲燕，左大明，张丽芸，卢晓，陈政良，周嘉

《南方医科大学学报》

2015

Mannan‐binding lectin at supraphysiological concentrations inhibits differentiation of dendritic cells from human CD14+ monocytes

Xiao‐Ying Xu, Huijie Li, Liyun Zhang, Xiao Lu, Da-ming Zuo, Guiqiu Shan, Tian‐Yu Xu, Zhengliang Chen

Microbiology and Immunology

DOI

2015

Mannan‐binding lectin reduces CpG DNA‐induced inflammatory cytokine production by human monocytes

Yuan Tang, Di Ma, Siqi Ming, Liyun Zhang, Jia Zhou, Guiqiu Shan, Zhengliang Chen, Xiao Lu, Daming Zuo

Microbiology and Immunology

DOI

2014

Mannan binding lectin attenuates double‐stranded RNA‐mediated TLR3 activation and innate immunity

Hongzhi Liu, Jia Zhou, Di Ma, Xiao Lu, Siqi Ming, Guiqiu Shan, Xiao‐Yong Zhang, Jinlin Hou, Zhengliang Chen, Daming Zuo

FEBS Letters

DOI

2013

甘露聚糖结合凝集素对人中性粒细胞功能的影响

陈阿德，王燕，张丽芸，卢晓，左大明，陈政良

《南方医科大学学报》

2013

抗MBL单抗1C8对人单核-巨噬细胞调理吞噬功能的影响及其机制

张毅，左大明，刘莹，张丽芸，卢晓，陈政良

《现代免疫学》

2013

Mannose-Binding Lectin Inhibits Monocyte Proliferation through Transforming Growth Factor-β1 and p38 Signaling Pathways

Yan Wang, A-De Chen, Yan‐Mei Lei, Guiqiu Shan, Liyun Zhang, Xiao Lu, Zhengliang Chen

PLoS ONE

DOI

2012

重组人甘露聚糖结合凝集素三肽链亚单位的制备及其活性分析

雷鸣，童俊容，卢晓，张丽芸，左大明，陈政良

《南方医科大学学报》

2012

Defective activities, but not secretions, resulting from gene point mutations of human mannan-binding lectin

Ying Liu, FENG-LING LIU, Zhi-jun Bai, Na Zhao, Liyun Zhang, Xiao Lu, Zhengliang Chen

Molecular Medicine Reports

DOI

2011

Mannan-binding lectin directly interacts with Toll-like receptor 4 and suppresses lipopolysaccharide-induced inflammatory cytokine secretion from THP-1 cells

Mingyong Wang, Yue Chen, Yani Zhang, Liyun Zhang, Xiao Lu, Zhengliang Chen

Cellular and Molecular Immunology

DOI

2011

Mannan-binding lectin regulates dendritic cell maturation and cytokine production induced by lipopolysaccharide

Mingyong Wang, Yani Zhang, Yue Chen, Liyun Zhang, Xiao Lu, Zhengliang Chen

BMC Immunology

DOI

2010

MBL抑制Jurkat细胞增殖和分泌IL-2

王明永，张雅妮，雷鸣，张丽芸，卢晓，陈政良

《现代免疫学》

2009

Balb/C小鼠甘露聚糖结合凝集素-A糖识别域的原核表达

左大明，张丽芸，卢晓，陈政良

《南方医科大学学报》

2009

Protective role of mouse MBL-C on intestinal mucosa during Shigella flexneri invasion

Daming Zuo, Liyun Zhang, Xiao Lu, Ying Liu, Zhengliang Chen

International Immunology

DOI

2008

MBL与人单核细胞系THP1/CD14细胞结合及其特性研究

张雅妮，王明永，雷鸣，卢晓，陈政良

《现代免疫学》

2008

MBL与Raji细胞结合特性的研究

王明永，张雅妮，张丽芸，卢晓，雷鸣，李瑞芳，陈政良

《生物化学与生物物理进展》

2006

MBL对LPS刺激的不同分化和活化状态THP1/CD14细胞产生TNF-α和IL-12的影响

陈月，余新沛，卢晓，陈政良

《中华微生物学和免疫学杂志》

2005

七种常见MBL基因单倍型标准质粒的构建

余新沛，陈月，张丽芸，卢晓，陈政良

《南方医科大学学报》

2005

广东地区汉族人MBL基因点突变的研究

钟成全，王方勇，吕成伟，余新沛，卢晓，张丽芸，陈政良

《细胞与分子免疫学杂志》

2005

人MBL糖识别域在大肠杆菌中的表达、纯化及鉴定

卢晓，朱平，张丽芸，刘莹，陈政良

《免疫学杂志》

2004

中国蒙古族人MBL基因启动子区SNP的研究

吕成伟，陈政良，王方勇，钟成全，张丽芸，卢晓

《免疫学杂志》

2004

PcDNA4/His C-MBL表达载体的构建及其在CHO细胞中的表达

白志军，张丽芸，林佐贤，卢晓，陈政良

《南方医科大学学报》

2003

Balb/c小鼠甘露聚糖结合凝集素-C基因的克隆与鉴定

王宏伟，陈政良，左大明，卢晓，余新沛

《南方医科大学学报》

2002

广东地区汉族人MBL基因GGC54GAC点突变的初步筛查

王方勇，陈政良，吕成伟，张丽芸，卢晓

《免疫学杂志》

2001

人甘露聚糖结合凝集素相关丝氨酸蛋白酶-2基因的克隆与鉴定

陈政良，张丽芸，乔贵林，卢晓

《南方医科大学学报》

2001

GGC54GAC MBL突变体的构建

陈政良，卢晓，张丽芸，韩强涛

《中国免疫学杂志》

1998

人血浆MBL的分离纯化及其特性鉴定

陈政良，韩强涛，易正山，张丽芸，卢晓，彭良平

《免疫学杂志》

精选作品

期刊论文

Mannan-binding lectin ameliorates renal fibrosis by suppressing macrophage-to-myofibroblast transition

MBL Binding with AhR Controls Th17 Immunity in Silicosis-Associated Lung Inflammation and Fibrosis

Mannan-Binding Lectin Reduces Epithelial-Mesenchymal Transition in Pulmonary Fibrosis via Inactivating the Store-Operated Calcium Entry Machinery

Mannan-Binding Lectin via Interaction With Cell Surface Calreticulin Promotes Senescence of Activated Hepatic Stellate Cells to Limit Liver Fibrosis Progression

Mannan-Binding Lectin Deficiency Limits Inflammation-induced Myeloid-Derived Suppressor Cells Expansion via Modulating Tumor Necrosis Factor Alpha-triggered Apoptosis

Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release

Mannan-Binding Lectin Regulates Inflammatory Cytokine Production, Proliferation, and Cytotoxicity of Human Peripheral Natural Killer Cells

Mannan‐binding lectin attenuates acetaminophen‐induced hepatotoxicity by regulating CYP2E1 expression via ROS‐dependent JNK/SP1 pathway

Mannan-binding lectin deficiency exacerbates sterile liver injury in mice through enhancing hepatic neutrophil recruitment

Mannan-binding lectin suppresses growth of hepatocellular carcinoma by regulating hepatic stellate cell activation via the ERK/COX-2/PGE2 pathway

肝细胞肝癌患者血浆中甘露聚糖结合凝集素和甘露聚糖结合凝集素相关丝氨酸蛋白酶-2的表达水平

Mannan‐binding lectin at supraphysiological concentrations inhibits differentiation of dendritic cells from human CD14+ monocytes

Mannan‐binding lectin reduces CpG DNA‐induced inflammatory cytokine production by human monocytes

Mannan binding lectin attenuates double‐stranded RNA‐mediated TLR3 activation and innate immunity

甘露聚糖结合凝集素对人中性粒细胞功能的影响

抗MBL单抗1C8对人单核-巨噬细胞调理吞噬功能的影响及其机制

Mannose-Binding Lectin Inhibits Monocyte Proliferation through Transforming Growth Factor-β1 and p38 Signaling Pathways

重组人甘露聚糖结合凝集素三肽链亚单位的制备及其活性分析

Defective activities, but not secretions, resulting from gene point mutations of human mannan-binding lectin

Mannan-binding lectin directly interacts with Toll-like receptor 4 and suppresses lipopolysaccharide-induced inflammatory cytokine secretion from THP-1 cells

Mannan-binding lectin regulates dendritic cell maturation and cytokine production induced by lipopolysaccharide

MBL抑制Jurkat细胞增殖和分泌IL-2

Balb/C小鼠甘露聚糖结合凝集素-A糖识别域的原核表达

Protective role of mouse MBL-C on intestinal mucosa during Shigella flexneri invasion

MBL与人单核细胞系THP1/CD14细胞结合及其特性研究

MBL与Raji细胞结合特性的研究

MBL对LPS刺激的不同分化和活化状态THP1/CD14细胞产生TNF-α和IL-12的影响

七种常见MBL基因单倍型标准质粒的构建

广东地区汉族人MBL基因点突变的研究

人MBL糖识别域在大肠杆菌中的表达、纯化及鉴定

中国蒙古族人MBL基因启动子区SNP的研究

PcDNA4/His C-MBL表达载体的构建及其在CHO细胞中的表达

Balb/c小鼠甘露聚糖结合凝集素-C基因的克隆与鉴定

广东地区汉族人MBL基因GGC54GAC点突变的初步筛查

人甘露聚糖结合凝集素相关丝氨酸蛋白酶-2基因的克隆与鉴定

GGC54GAC MBL突变体的构建

人血浆MBL的分离纯化及其特性鉴定

会议论文

MBL三聚体CRD制备与鉴定

研究方向