刘运美｜南华大学｜学者主页

2025

Porphyrin-ligustrazine conjugates: Dual-mode therapeutic agents combining photodynamic and chemotherapy for enhanced antitumor activity.

Lei Shi, Yihui Liu, Ze-Jie Tian, Chen Tang, Lin Yang, Ying Fang, Yi Wang, Yun-Mei Liu

Journal of Photochemistry and Photobiology. B: Biology

DOI

2025

Synthesis of porphyrin-formononetin derivatives and their anti-tumor activity studies

Lin Yang, Shan He, Chen Tang, Lei Shi, Zhenhua Liu, Ze-Jie Tian, Hui Li, Xufeng He, Jiding Liao, Yun-Mei Liu

Molecular diversity

DOI

2024

面向应用的仪器分析开放性实验设计研究

王洁琼，何穗穗，刘运美，王震，喻翠云，郭知鑫

《广东化工》

2024

Design, synthesis and antitumor study of novel NO-type porphyrin–ferulic acid derivatives for chemotherapy and photodynamic therapy

Zhenhua Liu, Lin Yang, Ze-Jie Tian, Hui Li, Lei Shi, Chen Tang, Yu Guo, Jun He, Yun-Mei Liu

New Journal of Chemistry

DOI

2024

Synthesis and Antitumor Activity of Photosensitizer Eugenol Porphyrin Derivatives: A Combination Therapy of Chemotherapy and Photodynamic Therapy

Hui Li, Chen Tang, Zhenhua Liu, Ze-Jie Tian, Lei Shi, Lin Yang, Jun He, Wenbin Ai, Xufeng He, Yun-Mei Liu

Applied organometallic chemistry

DOI

2023

含NO供体的水杨酸卟啉酯类化合物的合成、体外活性及作用机制

瑜文美，杨玲艳，刘振华，李辉，田泽杰，李嘉欣，易小婵，何军，刘运美

《湖南师范大学自然科学学报》

2023

Design, synthesis, antitumor activity and ct-DNA binding study of photosensitive drugs based on porphyrin framework.

Qizhi Zhang, Wen-Mei Yu, Z. Liu, Hui Li, Yihui Liu, Xin Liu, Zhaoshun Han, Jun He, Yaofu Zeng, Yu Guo, Yun-Mei Liu

International Journal of Biological Macromolecules

DOI

2023

Synthesis and antitumor study of novel porphyrin–coumarin derivatives for chemotherapy and photodynamic therapy

Ze-Jie Tian, Lei Shi, Z. Liu, Hui Li, Lin Yang, Yun-Mei Liu

Journal of Molecular Structure

DOI

2023

3D quantitative structure–activity relationships study on anti-gastric cancer of chrysin derivatives

Yun-Mei Liu, Ze-Jie Tian, Hui Li, Z. Liu, Lei Shi, Lin Yang

Journal of Mathematical Chemistry

DOI

2023

ROS-mediated Therapeutics Combined with Metal-based Porphyrin Nanoparticles and their Applications in Tumor Treatment.

Lin Yang, Lei Shi, Yihui Liu, Zhenhua Liu, Ze-Jie Tian, Hui Li, Jiayao Zhang, Jun He, Yun-Mei Liu

Current Medicinal Chemistry

DOI

2023

Enhanced Photodynamic Therapy by Improved Light Energy Capture Efficiency of Porphyrin Photosensitizers

Ze-Jie Tian, Hui Li, Z. Liu, Lin Yang, C. Zhang, Jun He, Wenbin Ai, Yun-Mei Liu

Current Treatment Options in Oncology

DOI

2022

Application of metalloporphyrin sensitizers for the treatment or diagnosis of tumors

Hong-Yu Luo, Wen-Mei Yu, Si Chen, Zhenyu Wang, Ze-Jie Tian, Jun He, Yun-Mei Liu

Journal Chemical Research

DOI

2022

Porphyrin-Based Nanoparticles: A Promising Phototherapy Platform.

Zhen-Hua Liu, Hui Li, Ze-Jie Tian, Xin Liu, Yu Guo, Jun He, Zhenyu Wang, Tao Zhou, Yun-Mei Liu

ChemPlusChem

DOI

2022

Reaction mechanism of nanomedicine based on porphyrin skeleton and its application prospects.

Hui Li, Wen-Yan Xiao, Ze-Jie Tian, Z. Liu, Lei Shi, Y. Wang, Yujie Liu, Yun-Mei Liu

Photodiagnosis and Photodynamic Therapy

DOI

2021

基于白杨素骨架的EGFR/PI3K双靶点抑制剂的设计、合成与抗癌活性研究

刘运美

《湖南师范大学》

2020

优化人才培养方案促进创新型药学人才培养

刘阳，雷小勇，郑兴，贺冬秀，刘运美，喻翠云

《卫生职业教育》

2020

仪器分析在线教学实践与思考

刘阳，刘运美，曾要富，彭俊梅，郭玉

《广州化工》

2020

A promising anticancer drug: a photosensitizer based on the porphyrin skeleton.

Qizhi Zhang, Jun He, Wen-Mei Yu, Yanchun Li, Zhenhua Liu, Binning Zhou, Yun-Mei Liu

RSC Medicinal Chemistry

DOI

2020

Porphyrin‐Based Metal−Organic Framework Compounds as Promising Nanomedicines in Photodynamic Therapy

Wen-Mei Yu, Wenqiang Zhen, Qizhi Zhang, Yanchun Li, Hong-Yu Luo, Jun He, Yun-Mei Liu

ChemMedChem

DOI

2020

Novel photosensitizing properties of porphyrin–chrysin derivatives with antitumor activity in vitro

Ding Liu, Qizhi Zhang, Lang Zhang, Wen-Mei Yu, Hui Long, Jun He, Yun-Mei Liu

Journal Chemical Research

DOI

2019

Synthesis, characterization and preliminary biological evaluation of chrysin amino acid derivatives that induce apoptosis and EGFR downregulation

Yun-Mei Liu, Yang Li, Ronggang Liu, J. Xiao, Binning Zhou, Qizhi Zhang, Jian-Xin Song

Journal of Asian natural products research

DOI

2019

Design, synthesis, and preliminary biological evaluation of chrysin amino acid derivatives that induce apoptosis and suppress cell migration

Yun-Mei Liu, Yang Li, J. Xiao, Qizhi Zhang, Jian-Xin Song

Journal of Asian natural products research

DOI

2019

The Relationship between Pharmacological Properties and Structure- Activity of Chrysin Derivatives.

Yang Li, Yan-Peng Li, Jun He, Ding Liu, Qizhi Zhang, Kang Li, Xing Zheng, Guo-Tao Tang, Yu Guo, Yun-Mei Liu

Mini-Reviews in Medical Chemistry

DOI

2019

The association between anti-tumor potency and structure-activity of protein-kinases inhibitors based on quinazoline molecular skeleton.

Yang Li, J. Xiao, Qizhi Zhang, Wen-Mei Yu, Meng-Qin Liu, Yu Guo, Jun He, Yun-Mei Liu

Bioorganic & Medicinal Chemistry

DOI

2018

新型卟啉-白杨素复合物的合成及其体外抗肿瘤MCF-7细胞的研究

刘鼎，何军，成林，张奇志，刘运美

《广东化工》

2018

卟啉衍生物的合成与性能研究进展（英文）

刘鼎，成林，何军，郭玉，刘运美

《化学通报(中英文)》

2018

有机药物波谱解析教学改革探讨

刘阳，杨寒幸，刘运美，彭俊梅，贺冬秀

《药学教育》

2018

7-O-氨基酸取代白杨素衍生物的合成及抗肿瘤活性

Ding Liu, Yan-Peng Li, Hong-Xiu Shen, Yang Li, He Jun, Qizhi Zhang, Yun-Mei Liu

2018

Synthesis and evaluation of antitumour activity in vitro and in vivo of chrysin salicylate derivatives

Xiang-Ping Deng, Zi-Hao Zhao, Shujuan Xiong, Runde Xiong, Juan Liu, Zhe Wang, L. Zou, Xiao-Yong Lei, Xuan Cao, Zhi-Zhong Xie, Yanming Chen, Xing Zheng, Yun-Mei Liu, Guo-Tao Tang

Natural Product Research

DOI

2018

Synthesis of novel genistein amino acid derivatives and investigation on their interactions with bovine serum albumin by spectroscopy and molecular docking

Xiaokang Long, Yao‐Fu Zeng, Yun-Mei Liu, Ying Liu, T. Li, Lanqing Liao, Yu Guo

RSC Advances

DOI

2018

Design, synthesis and biological evaluation of chrysin benzimidazole derivatives as potential anticancer agents

Zhe Wang, Xiang-Ping Deng, Shujuan Xiong, Runde Xiong, Juan Liu, L. Zou, Xiao-Yong Lei, Xuan Cao, Zhi-Zhong Xie, Yanming Chen, Yun-Mei Liu, Xing Zheng, Guo-Tao Tang

Natural Product Research

DOI

2018

Synthesis and anti-tumor activities of novel 7-O-amino acids chrysin derivatives

Ding Liu, Yan-Peng Li, Hong-Xiu Shen, Yang Li, Jun He, Qizhi Zhang, Yun-Mei Liu

Chinese Herbal Medicines

DOI

2017

药学专业《仪器分析》课程教学改革探索

刘阳，贺艳，刘运美，彭俊梅，郭玉

《广州化工》

2017

异丙酰基为桥合成白杨素氨基酸衍生物及其抗癌活性研究

刘容芳，何军，沈洪秀，刘鼎，李洋，郑兴，唐国涛，郭玉，刘运美

《肿瘤药学》

2017

Spectroscopic and molecular docking study on the structure-affinity relationship and mechanism in the interaction of genistein and its derivatives with bovine serum albumin.

Yu Guo, Li-xian Shen, X. Yao, Yang Liu, Yun-Mei Liu, Hongfei Chen, K. Min, Xing Zheng

Luminescence (Chichester, England Print)

DOI

2016

药学专业《分析化学》课程的信息化教学改革初探

刘阳，刘运美，彭俊梅，郭玉

《医学教育研究与实践》

2016

浅谈如何提高药学专业学生学习有机药物波谱解析的兴趣

彭俊梅，刘映，刘运美，刘阳，唐国涛

《广东化工》

2016

含磷白杨素衍生物合成的研究进展

沈洪秀，何军，刘容芳，刘鼎，李艳鹏，成林，刘运美

《肿瘤药学》

2015

7-O-羧烷基化白杨素衍生物的合成及其抗癌活性

宋秀道，何军，马锦，郑兴，雷小勇，刘运美，郭玉

《合成化学》

2015

白杨素衍生物的合成及其抗癌活性研究

赵子淏，敖宝学，魏云，刘运美，谢志忠，曹轩，郑兴，唐国涛

《肿瘤药学》

2015

Synthesis of novel amino acid derivatives containing chrysin as anti-tumor agents against human gastric carcinoma MGC-803 cells

Xiu-Dao Song, Yun-Mei Liu, Jin Ma, Jun He, Xing Zheng, Xiao-Yong Lei, G. Jiang, Lu-Rong Zhang

Medicinal Chemistry Research

DOI

2015

Synthesis, Characterization, and Anticancer Effect of Trifluoromethylated Aurone Derivatives

Xing Zheng, Hui Wang, Yun-Mei Liu, X. Yao, Min Tong, Yu-Hong Wang, D. Liao

DOI

2014

白杨素甘氨酸类化合物的合成及抗癌活性

宋秀道，何军，马锦，刘运美，郑兴，雷小勇，郭玉

《高等学校化学学报》

2014

普通高校药学专业“三级平台”式实践教学体系的构建

刘运美，雷小勇，郭玉，郑兴，唐国涛，黄红林

《中国高等医学教育》

2014

Synthesis of new 7-O-modified chrysin derivatives and their anti-proliferative and apoptotic effects on human gastric carcinoma MGC-803 cells

Yun-Mei Liu, Xiu-Dao Song, Jin Ma, Jun He, Xing Zheng, Xiao-Yong Lei, G. Jiang, Zi-Hao Zhao, Xia Pan

Chemical Research in Chinese Universities

DOI

2014

Synthetic derivatives of chrysin and their biological activities

Yun-Mei Liu, Xiu-Dao Song, Jun He, Xing Zheng, Hou Wu

Medicinal Chemistry Research

DOI

2013

依托医学教育资源创建药学专业课程新体系

高治平，黄红林，郭玉，庹勤慧，郭紫芬，涂剑，刘运美，汪煜华，雷小勇

《基础医学教育》

2012

新手模型法命名手性分子R/S构型

李云贵，李冲，刘奕训，刘运美，郭玉

《广州化工》

2012

《仪器分析实验》教学实践与探索

郑兴，闫文娜，刘运美，郭玉

《时代教育》

2011

药学专业学生实践教学模式的探讨

汪煜华，刘运美，郑兴，秦旭平，郭紫芬，罗其富，雷小勇，谢志忠，黄红林

《医学教育研究与实践》

2011

溴代白杨素衍生物合成及其抗癌活性

郑兴，王小平，刘运美，郭玉，罗星，尹松，代琴，朱琼妮，廖端芳

《时珍国医国药》

2011

B环碘取代白杨素的合成及其抗癌活性研究

郑兴，罗星，郭玉，刘运美，王小平，尹松，代琴，刘国刚，廖端芳

《中国医药导刊》

2010

B环溴取代的白杨素衍生物合成及其抗癌活性

郑兴，许雪梅，郭玉，刘运美，罗星，王小平，尹松，代琴，朱琼妮

《中南医学科学杂志》

2010

药学专业实验教学改革及其实验室建设研究

高治平，刘刚，刘运美，郑兴，雷小勇，唐圣松，廖端芳

《医学教育研究与实践》

2010

Synthesis and preliminary biological evaluation of chrysin derivatives as potential anticancer drugs.

Xing Zheng, Fei-Fei Zhao, Yun-Mei Liu, X. Yao, Zitong Zheng, Xing-rui Luo, D. Liao

Medicinal chemistry

DOI

2009

天然药物化学理论课信息化教学探析

贺冬秀，郑兴，何小珍，刘运美

《科技资讯》

2009

B环三氟甲基取代的白杨素衍生物合成及其抗癌活性

许雪梅，赵菲菲，郑兴，刘运美，姚旭，罗星，黄进，郑自通，牛明辉，廖端芳

《中南医学科学杂志》

2009

药学专业人才培养模式的研究与探索

刘运美，唐圣松，郑兴，雷小勇，高治平，廖端芳

《中国高等医学教育》

2009

Synthesis and cytotoxic activity of genistein derivatives

Xing Zheng, Xu Yao, Yunmei Liu, Zitong Zheng, Jianguo Cao, Duan‐Fang Liao

Medicinal Chemistry Research

DOI

2008

药学专业本科生“导师制”应用的实践与体会

涂剑，雷小勇，唐圣松，郭玉，刘运美

《医学教育研究与实践》

2008

Practice and Personal Experience of Tutorial System for Undergraduates of Pharmacy Specialty at Our University

Yun-Mei Liu

精选作品

期刊论文

Porphyrin-ligustrazine conjugates: Dual-mode therapeutic agents combining photodynamic and chemotherapy for enhanced antitumor activity.

Synthesis of porphyrin-formononetin derivatives and their anti-tumor activity studies

面向应用的仪器分析开放性实验设计研究

Design, synthesis and antitumor study of novel NO-type porphyrin–ferulic acid derivatives for chemotherapy and photodynamic therapy

Synthesis and Antitumor Activity of Photosensitizer Eugenol Porphyrin Derivatives: A Combination Therapy of Chemotherapy and Photodynamic Therapy

含NO供体的水杨酸卟啉酯类化合物的合成、体外活性及作用机制

Design, synthesis, antitumor activity and ct-DNA binding study of photosensitive drugs based on porphyrin framework.

Synthesis and antitumor study of novel porphyrin–coumarin derivatives for chemotherapy and photodynamic therapy

3D quantitative structure–activity relationships study on anti-gastric cancer of chrysin derivatives

ROS-mediated Therapeutics Combined with Metal-based Porphyrin Nanoparticles and their Applications in Tumor Treatment.

Enhanced Photodynamic Therapy by Improved Light Energy Capture Efficiency of Porphyrin Photosensitizers

Application of metalloporphyrin sensitizers for the treatment or diagnosis of tumors

Porphyrin-Based Nanoparticles: A Promising Phototherapy Platform.

Reaction mechanism of nanomedicine based on porphyrin skeleton and its application prospects.

基于白杨素骨架的EGFR/PI3K双靶点抑制剂的设计、合成与抗癌活性研究

优化人才培养方案 促进创新型药学人才培养

仪器分析在线教学实践与思考

A promising anticancer drug: a photosensitizer based on the porphyrin skeleton.

Porphyrin‐Based Metal−Organic Framework Compounds as Promising Nanomedicines in Photodynamic Therapy

Novel photosensitizing properties of porphyrin–chrysin derivatives with antitumor activity in vitro

Synthesis, characterization and preliminary biological evaluation of chrysin amino acid derivatives that induce apoptosis and EGFR downregulation

Design, synthesis, and preliminary biological evaluation of chrysin amino acid derivatives that induce apoptosis and suppress cell migration

The Relationship between Pharmacological Properties and Structure- Activity of Chrysin Derivatives.

The association between anti-tumor potency and structure-activity of protein-kinases inhibitors based on quinazoline molecular skeleton.

新型卟啉-白杨素复合物的合成及其体外抗肿瘤MCF-7细胞的研究

卟啉衍生物的合成与性能研究进展（英文）

有机药物波谱解析教学改革探讨

7-O-氨基酸取代白杨素衍生物的合成及抗肿瘤活性

Synthesis and evaluation of antitumour activity in vitro and in vivo of chrysin salicylate derivatives

Synthesis of novel genistein amino acid derivatives and investigation on their interactions with bovine serum albumin by spectroscopy and molecular docking

Design, synthesis and biological evaluation of chrysin benzimidazole derivatives as potential anticancer agents

Synthesis and anti-tumor activities of novel 7-O-amino acids chrysin derivatives

药学专业《仪器分析》课程教学改革探索

异丙酰基为桥合成白杨素氨基酸衍生物及其抗癌活性研究

Spectroscopic and molecular docking study on the structure-affinity relationship and mechanism in the interaction of genistein and its derivatives with bovine serum albumin.

药学专业《分析化学》课程的信息化教学改革初探

浅谈如何提高药学专业学生学习有机药物波谱解析的兴趣

含磷白杨素衍生物合成的研究进展

7-O-羧烷基化白杨素衍生物的合成及其抗癌活性

白杨素衍生物的合成及其抗癌活性研究

Synthesis of novel amino acid derivatives containing chrysin as anti-tumor agents against human gastric carcinoma MGC-803 cells

Synthesis, Characterization, and Anticancer Effect of Trifluoromethylated Aurone Derivatives

白杨素甘氨酸类化合物的合成及抗癌活性

普通高校药学专业“三级平台”式实践教学体系的构建

Synthesis of new 7-O-modified chrysin derivatives and their anti-proliferative and apoptotic effects on human gastric carcinoma MGC-803 cells

Synthetic derivatives of chrysin and their biological activities

依托医学教育资源创建药学专业课程新体系

新手模型法命名手性分子R/S构型

《仪器分析实验》教学实践与探索

药学专业学生实践教学模式的探讨

溴代白杨素衍生物合成及其抗癌活性

B环碘取代白杨素的合成及其抗癌活性研究

B环溴取代的白杨素衍生物合成及其抗癌活性

药学专业实验教学改革及其实验室建设研究

Synthesis and preliminary biological evaluation of chrysin derivatives as potential anticancer drugs.

天然药物化学理论课信息化教学探析

B环三氟甲基取代的白杨素衍生物合成及其抗癌活性

药学专业人才培养模式的研究与探索

Synthesis and cytotoxic activity of genistein derivatives

药学专业本科生“导师制”应用的实践与体会

Practice and Personal Experience of Tutorial System for Undergraduates of Pharmacy Specialty at Our University

会议论文

含氟白藜芦醇衍生物的合成及抗癌活性研究

研究方向

优化人才培养方案促进创新型药学人才培养