巩帅｜山东农业大学｜学者主页

2026

Animal Age-Dependent Susceptibility of Mouse Oocytes to Zearalenone-Induced Developmental Impairment: Roles of Pharmacokinetic Exposure and Intrinsic Oocyte Sensitivity

Si-Tong Liu, Jun-Gui Zhao, Jia-Li Xu, Min Zhang, Shuai Gong, Hong-Jie Yuan, Jing‐He Tan, Ming‐Jiu Luo

Cells

DOI

2026

Biphasic Responses of Porcine Oocytes to Metformin: Concentration-Dependent AMPK Activation and Nrf2-Mediated Antioxidant Regulation

Junyu Wang, M Y Li, Yaqi Zhou, Fuyin Fu, Feng Liu, Jing‐He Tan, Ming‐Jiu Luo, Shuai Gong

Animals

DOI

2025

Optimized protocols of meiotic arrest maintenance improved in vitro maturation of ovine oocytes

Nan He, Yong-Qi Wang, Lin Jiang, Tian-Hao Bai, Mengmeng Wang, Min Zhang, Jiali Xu, Shuai Gong, Hong-Jie Yuan, Jing‐He Tan, Ming‐Jiu Luo

Reproduction Fertility and Development

DOI

2025

Expression Profiling and Function Analysis Identified New Cumulus Cells-Expressed Genes and miRNAs Predictive of Oocyte Developmental Potential

Min Zhang, Mengmeng Wang, Fa‐Li Zhang, Nan He, Ming‐Jiu Luo, Shuai Gong, Fu-Yin Fu, Hongjie Yuan, Jie Zhang, Jing‐He Tan

Cells

DOI

2025

Cumulus cells and the TNF-alpha signaling facilitate aging of ovine oocytes

Shuai Gong, Yan Zhang, Chao-Qun Cong, Guo‐Liang Wang, Lin Jiang, Hong-Jie Yuan, Jing‐He Tan, Ming‐Jiu Luo

Theriogenology

DOI

2024

Role and action mechanisms of miR-149 and miR-31 in regulating function of pig cumulus cells and oocytes

Jia-Shun Wu, Shuai Gong, Min Zhang, Rui-Jie Ma, Hui-Li Wang, Ming‐Jiu Luo, Nan He, Jing‐He Tan

Theriogenology

DOI

2024

Postovulatory Aging of Mouse Oocytes Impairs Offspring Behavior by Causing Oxidative Stress and Damaging Mitochondria

Mingtao Xu, Min Zhang, Guo‐Liang Wang, Shuai Gong, Ming‐Jiu Luo, Jie Zhang, Hong-Jie Yuan, Jing‐He Tan

Cells

DOI

2023

High glucose exposure of preimplantation embryos causes glucose intolerance and insulin resistance in F1 and F2 male offspring

Guoliang Wang, Hong-Jie Yuan, Qiao-Qiao Kong, Jie Zhang, Han Xiao, Shuai Gong, Mingtao Xu, Nan He, Ming‐Jiu Luo, Jing‐He Tan

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

DOI

2023

Role of tPA in Corticosterone-Induced Apoptosis of Mouse Mural Granulosa and Oviductal Epithelial Cells

Hua Qi, Hao Cheng, Yong-Qing Yang, Jin-Song An, Min Zhang, Shuai Gong, Ming‐Jiu Luo, Jing‐He Tan

Cells

DOI

2022

Glucocorticoid Exposure of Preimplantation Embryos Increases Offspring Anxiety-Like Behavior by Upregulating miR-211-5p via Trpm1 Demethylation

Hong-Jie Yuan, Xiao Han, Guoliang Wang, Jia-Shun Wu, Nan He, Jie Zhang, Qiao-Qiao Kong, Shuai Gong, Ming‐Jiu Luo, Jing‐He Tan

Frontiers in Cell and Developmental Biology

DOI

2022

Topoisomerase II dysfunction causes metaphase I arrest by activating Aurora B, SAC and MPF and prevents PB1 abscission in mouse oocytes

Jie Zhang, Hong-Jie Yuan, Jiang Zhu, Shuai Gong, Ming‐Jiu Luo, Jing‐He Tan

Biology of Reproduction

DOI

2022

Hypothalamic-Pituitary-Adrenal Hormones Impair Pig Fertilization and Preimplantation Embryo Development via Inducing Oviductal Epithelial Apoptosis: An In Vitro Study

Jin-Song An, Guoliang Wang, Dongming Wang, Yong-Qing Yang, Jia-Shun Wu, Ying‐Qi Zhao, Shuai Gong, Jing‐He Tan

Cells

DOI

2021

Effects of CRH and ACTH exposure during in vitro maturation on competence of pig and mouse oocytes

Shuai Gong, Lin Jiang, Hao Cheng, Liu‐Zhu Pan, Mingtao Xu, Min Zhang, Hong-Jie Yuan, Jing‐He Tan

Theriogenology

DOI

2021

In vivo zearalenone exposure dose-dependently compromises mouse oocyte competence by impairing chromatin configuration and gene transcription

Liu‐Zhu Pan, Hao Cheng, Jie Zhang, Shuai Gong, Xiaodan Tian, Cheng-Jie Pan, Ming‐Jiu Luo, Jing‐He Tan

Reproduction Fertility and Development

DOI

2021

Expression profiling and function analysis identified new microRNAs regulating cumulus expansion and apoptosis in cumulus cells

Han Xiao, Min Zhang, Hong-Jie Yuan, Guoliang Wang, Xinyue Zhao, Zhibin Li, Shuai Gong, Jing‐He Tan

Molecular Human Reproduction

DOI

2021

Ethylene glycol butyl ether deteriorates oocyte quality via impairing mitochondrial function

Xiaoyan Shi, Yilong Miao, Kemei Zhang, Shuai Gong, Bo Xiong

The FASEB Journal

DOI

2021

Follicular development in livestock: Influencing factors and underlying mechanisms

Yanjun Zhang, Shuai Gong, Yanping Su, Minhua Yao, Xiaocui Liu, Zhaoqing Gong, Hongshu Sui, Ming‐Jiu Luo

Animal Science Journal

DOI

2020

Role of AMP-activated protein kinase during postovulatory aging of mouse oocytes†

Guang-Yi Sun, Shuai Gong, Qiao-Qiao Kong, Zhibin Li, Jia Wang, Mingtao Xu, Ming‐Jiu Luo, Jing‐He Tan

Biology of Reproduction

DOI

2020

Meiotic block with roscovitine improves competence of porcine oocytes by fine‐tuning activities of different cyclin‐dependent kinases

Shuai Zhu, Ying‐Jun Jia, Liu‐Zhu Pan, Shuai Gong, Mingju Sun, Guo‐Liang Wang, Ming‐Jiu Luo, Jing‐He Tan

Journal of Cellular Physiology

DOI

2020

Corticosterone induced apoptosis of mouse oviduct epithelial cells independent of the TNF-α system

Ying-Qi ZHAO, Ren-Ren Chen, Qiao-Qiao Kong, Jin-Song An, Xinyue Zhao, Shuai Gong, Hong-Jie Yuan, Jing‐He Tan

Journal of Reproduction and Development

DOI

2020

Heat stress decreases egg production of laying hens by inducing apoptosis of follicular cells via activating the FasL/Fas and TNF-α systems

Guiming Li, Li-Ping Liu, Bin Yin, Yueyue Liu, Wen-Wen Dong, Shuai Gong, Jie Zhang, Jing‐He Tan

Poultry Science

DOI

2020

Effects of glucose metabolism pathways on nuclear and cytoplasmic maturation of pig oocytes

Jing Wen, Guoliang Wang, Hong-Jie Yuan, Jie Zhang, Hongli Xie, Shuai Gong, Han Xiao, Jing‐He Tan

Scientific Reports

DOI

2018

HPA轴产物对猪和小鼠卵母细胞体外成熟和发育能力的影响及作用机理

巩帅

《山东农业大学》

2018

丙酮酸和乳酸代谢对猪卵母细胞体外核成熟的作用

温晶，王国梁，巩帅，解洪立，谭景和

《中国兽医学报》

2017

Mechanisms for the species difference between mouse and pig oocytes in their sensitivity to glucorticoids†

Shuai Gong, Guang-Yi Sun, Min Zhang, Hong-Jie Yuan, Shuai Zhu, Guang-Zhong Jiao, Ming‐Jiu Luo, Jing‐He Tan

Biology of Reproduction

DOI

2017

Meiotic arrest with roscovitine and follicular fluid improves cytoplasmic maturation of porcine oocytes by promoting chromatin de-condensation and gene transcription

Min Zhang, Chuanxin Zhang, Liu‐Zhu Pan, Shuai Gong, Wei Cui, Hong-Jie Yuan, Wei-Ling Zhang, Jing‐He Tan

Scientific Reports

DOI

2017

Corticotrophin-releasing hormone and corticosterone impair development of preimplantation embryos by inducing oviductal cell apoptosis via activating the Fas system: an in vitro study

Xiuwen Tan, Chang-Li Ji, Liang-Liang Zheng, Jie Zhang, Hong-Jie Yuan, Shuai Gong, Jiang Zhu, Jing‐He Tan

Human Reproduction

DOI

2016

Parental life events cause behavioral difference among offspring: Adult pre-gestational restraint stress reduces anxiety across generations

Nan He, Qiao-Qiao Kong, Jun-Zuo Wang, Shu-Fen Ning, Yilong Miao, Hong-Jie Yuan, Shuai Gong, Xiang-Zhong Cui, Chuan-Yong Li, Jing‐He Tan

Scientific Reports

DOI

2016

Glucocorticoids impair oocyte developmental potential by triggering apoptosis of ovarian cells via activating the Fas system

Hong-Jie Yuan, Han Xiao, Nan He, Guoliang Wang, Shuai Gong, Juan Lin, Min Gao, Jing‐He Tan

Scientific Reports

DOI

2016

An essential role for the intra-oocyte MAPK activity in the NSN-to-SN transition of germinal vesicle chromatin configuration in porcine oocytes

Mingju Sun, Shuai Zhu, You-Wei Li, Juan Lin, Shuai Gong, Guang-Zhong Jiao, Fei Chen, Jing‐He Tan

Scientific Reports

DOI

2015

不同生理或应激状态小鼠血清中皮质醇和皮质酮的变化规律及相关性

巩帅

《山东农业大学》

2015

Optimized Protocols for In Vitro Maturation of Rat Oocytes Dramatically Improve Their Developmental Competence to a Level Similar to That of Ovulated Oocytes

Guang-Zhong Jiao, Wei Cui, Rui Jie Yang, Juan Lin, Shuai Gong, Hua-Yu Lian, Mingju Sun, Jing‐He Tan

Cellular Reprogramming

DOI

2015

Restraint Stress on Female Mice Diminishes the Developmental Potential of Oocytes

Xiu-Fen Wu, Hong-Jie Yuan, Hong Li, Shuai Gong, Juan Lin, Yilong Miao, Tian-Yang Wang, Jing‐He Tan

Obstetrical & Gynecological Survey

DOI

2015

Dynamics and Correlation of Serum Cortisol and Corticosterone under Different Physiological or Stressful Conditions in Mice

Shuai Gong, Yi-Long Miao, Guang-Zhong Jiao, Ming-Ju Sun, Hong Li, Juan Lin, Ming‐Jiu Luo, Jing‐He Tan

PLoS ONE

DOI

2015

Concentrations of serum cortisol and corticosterone in female mice (n = 6) at different times (h) of acute restraint stress.

Shuai Gong, Yi-Long Miao, Guang-Zhong Jiao, Ming-Ju Sun, Hong Li, Juan Lin, Ming-Jiu Luo, Jing-He Tan

DOI

2014

Restraint Stress on Female Mice Diminishes the Developmental Potential of Oocytes: Roles of Chromatin Configuration and Histone Modification in Germinal Vesicle Stage Oocytes1

Xiu-Fen Wu, Hong-Jie Yuan, Hong Li, Shuai Gong, Juan Lin, Yilong Miao, Tian-Yang Wang, Jing‐He Tan

Biology of Reproduction

DOI

2014

Carrying-Over Effects of GVBD Blocking on Post-Blocking Meiotic Progression of Oocytes: Species Difference and the Signaling Pathway Leading to MPF Activation

Guang-Zhong Jiao, Hua-Yu Lian, Yan Gao, Mingju Sun, Shuai Gong, Liang-Liang Zheng, Chuanxin Zhang, Jing‐He Tan

PLoS ONE

DOI

2014

Western blot analysis for levels of Cyclin B, total CDC2A, inactive and active p-CDC2A in mouse oocytes following GVBD blocking for different times with roscovitine.

Guang-Zhong Jiao, Hua-Yu Lian, Yan Gao, Ming-Ju Sun, Shuai Gong, Liang-Liang Zheng, Chuan-Xin Zhang, Jing-He Tan

DOI

精选作品

期刊论文

Animal Age-Dependent Susceptibility of Mouse Oocytes to Zearalenone-Induced Developmental Impairment: Roles of Pharmacokinetic Exposure and Intrinsic Oocyte Sensitivity

Biphasic Responses of Porcine Oocytes to Metformin: Concentration-Dependent AMPK Activation and Nrf2-Mediated Antioxidant Regulation

Optimized protocols of meiotic arrest maintenance improved in vitro maturation of ovine oocytes

Expression Profiling and Function Analysis Identified New Cumulus Cells-Expressed Genes and miRNAs Predictive of Oocyte Developmental Potential

Cumulus cells and the TNF-alpha signaling facilitate aging of ovine oocytes

Role and action mechanisms of miR-149 and miR-31 in regulating function of pig cumulus cells and oocytes

Postovulatory Aging of Mouse Oocytes Impairs Offspring Behavior by Causing Oxidative Stress and Damaging Mitochondria

High glucose exposure of preimplantation embryos causes glucose intolerance and insulin resistance in F1 and F2 male offspring

Role of tPA in Corticosterone-Induced Apoptosis of Mouse Mural Granulosa and Oviductal Epithelial Cells

Glucocorticoid Exposure of Preimplantation Embryos Increases Offspring Anxiety-Like Behavior by Upregulating miR-211-5p via Trpm1 Demethylation

Topoisomerase II dysfunction causes metaphase I arrest by activating Aurora B, SAC and MPF and prevents PB1 abscission in mouse oocytes

Hypothalamic-Pituitary-Adrenal Hormones Impair Pig Fertilization and Preimplantation Embryo Development via Inducing Oviductal Epithelial Apoptosis: An In Vitro Study

Effects of CRH and ACTH exposure during in vitro maturation on competence of pig and mouse oocytes

In vivo zearalenone exposure dose-dependently compromises mouse oocyte competence by impairing chromatin configuration and gene transcription

Expression profiling and function analysis identified new microRNAs regulating cumulus expansion and apoptosis in cumulus cells

Ethylene glycol butyl ether deteriorates oocyte quality via impairing mitochondrial function

Follicular development in livestock: Influencing factors and underlying mechanisms

Role of AMP-activated protein kinase during postovulatory aging of mouse oocytes†

Meiotic block with roscovitine improves competence of porcine oocytes by fine‐tuning activities of different cyclin‐dependent kinases

Corticosterone induced apoptosis of mouse oviduct epithelial cells independent of the TNF-α system

Heat stress decreases egg production of laying hens by inducing apoptosis of follicular cells via activating the FasL/Fas and TNF-α systems

Effects of glucose metabolism pathways on nuclear and cytoplasmic maturation of pig oocytes

HPA轴产物对猪和小鼠卵母细胞体外成熟和发育能力的影响及作用机理

丙酮酸和乳酸代谢对猪卵母细胞体外核成熟的作用

Mechanisms for the species difference between mouse and pig oocytes in their sensitivity to glucorticoids†

Meiotic arrest with roscovitine and follicular fluid improves cytoplasmic maturation of porcine oocytes by promoting chromatin de-condensation and gene transcription

Corticotrophin-releasing hormone and corticosterone impair development of preimplantation embryos by inducing oviductal cell apoptosis via activating the Fas system: an in vitro study

Parental life events cause behavioral difference among offspring: Adult pre-gestational restraint stress reduces anxiety across generations

Glucocorticoids impair oocyte developmental potential by triggering apoptosis of ovarian cells via activating the Fas system

An essential role for the intra-oocyte MAPK activity in the NSN-to-SN transition of germinal vesicle chromatin configuration in porcine oocytes

不同生理或应激状态小鼠血清中皮质醇和皮质酮的变化规律及相关性

Optimized Protocols for In Vitro Maturation of Rat Oocytes Dramatically Improve Their Developmental Competence to a Level Similar to That of Ovulated Oocytes

Restraint Stress on Female Mice Diminishes the Developmental Potential of Oocytes

Dynamics and Correlation of Serum Cortisol and Corticosterone under Different Physiological or Stressful Conditions in Mice

Concentrations of serum cortisol and corticosterone in female mice (n = 6) at different times (h) of acute restraint stress.

Restraint Stress on Female Mice Diminishes the Developmental Potential of Oocytes: Roles of Chromatin Configuration and Histone Modification in Germinal Vesicle Stage Oocytes1

Carrying-Over Effects of GVBD Blocking on Post-Blocking Meiotic Progression of Oocytes: Species Difference and the Signaling Pathway Leading to MPF Activation

Western blot analysis for levels of Cyclin B, total CDC2A, inactive and active p-CDC2A in mouse oocytes following GVBD blocking for different times with roscovitine.

研究方向