李牧｜华中农业大学｜学者主页

2026

转录因子MpSte12调控红曲菌生长与红曲色素合成的机制研究

王婷雅，刘羽婷，李牧

《华中农业大学学报》

2026

Machine Learning-Guided Cofactor Engineering for Tunable Azaphilone Component Ratios in Monascus spp.

Wenrui Huang, Jiajia Li, Yali Duan, Yuting Liu, Nanwei Wang, Mu Li

Journal of Agricultural and Food Chemistry

DOI

2026

A Novel Angiotensin I-Converting Enzyme Inhibitory Pentapeptide from Red Mold Rice: Identification, Stability, In V i vo Antihypertensive Effects, and Underlying Mechanisms

Yuting Liu, Tingya Wang, Zitong Meng, Xinjie Han, Wenrui Huang, Mu Li

Journal of Agricultural and Food Chemistry

DOI

2026

Corrigendum to “Metabolic modulation of TCA cycle by S-nitrosylation in Monascus spp.” [Synthetic and Systems Biotechnol 12 (2026) 490–501]

Zitong Meng, Yingao Tan, Yali Duan, Mu Li

Synthetic and Systems Biotechnology

DOI

2026

Metabolic modulation of TCA cycle by S-nitrosylation in Monascus spp.

Zitong Meng, Yingao Tan, Yali Duan, Mu Li

Synthetic and Systems Biotechnology

DOI

2024

基于比较基因组学的红曲霉VeA、VelB生物信息学分析

黄汇惠，何霞，王丽玲，冉珍艳，王文华，何毅，李牧

《食品研究与开发》

2024

Monaspin B, a Novel Cyclohexyl-furan from Cocultivation of Monascus purpureus and Aspergillus oryzae, Exhibits Potent Antileukemic Activity

Zitong Meng, Yingao Tan, Yali Duan, Mu Li

Journal of Agricultural and Food Chemistry

DOI

2024

The serine/threonine protein kinase MpSTE1 directly governs hyphal branching in Monascus spp.

Yali Duan, Xizhu Chen, Tingya Wang, Mu Li

Applied Microbiology and Biotechnology

DOI

2023

Modular and Flexible Molecular Device for Simultaneous Cytosine and Adenine Base Editing at Random Genomic Loci in Filamentous Fungi

Yali Duan, Yingao Tan, Xizhu Chen, Xiaolin Pei, Mu Li

ACS Synthetic Biology

DOI

2023

Engineered aldoxime dehydratase to enable the chemoenzymatic conversion of benzyl amines to aromatic nitriles

Qinjie Xiao, Yumin Feng, Li Chen, Mu Li, Pengfei Zhang, Qiuyan Wang, Anming Wang, Anming Wang, Xiaolin Pei

Bioorganic Chemistry

DOI

2023

Versatile Strategy for the Construction of a Transcription Factor-Based Orthogonal Gene Expression Toolbox in Monascus spp

Yali Duan, Yingao Tan, Xuetuan Wei, Xiaolin Pei, Mu Li

ACS Synthetic Biology

DOI

2022

鉴定红曲菌中萘醌响应基因提高红曲色素产率

范菲，段雅丽，刘亚鹏，余沛霖，雷鸣，陈少云，李牧

《食品与发酵工业》

DOI

2022

Systematic Metabolic Engineering for the Production of Azaphilones in Monascus purpureus HJ11

Yali Duan, Yun Du, Zhiqiang Yi, Zhe Wang, Xiaolin Pei, Xuetuan Wei, Mu Li

Journal of Agricultural and Food Chemistry

DOI

2022

Dynamic regulation of Monascus azaphilones biosynthesis by the binary MrPigE-MrPigF oxidoreductase system

Yali Duan, Hongmin Ma, Xuetuan Wei, Mu Li

Applied Microbiology and Biotechnology

DOI

2022

An efficient microbial-based method for production of high-purity Monascus azaphilones pigments

Yali Duan, Lili Jia, Xiaolin Pei, Xuetuan Wei, Mu Li

LWT

DOI

2022

Programing a cyanide-free transformation of aldehydes to nitriles and one-pot synthesis of amides through tandem chemo-enzymatic cascades

Haoteng Zheng, Qinjie Xiao, Feiying Mao, Anming Wang, Mu Li, Qiuyan Wang, Pengfei Zhang, Xiaolin Pei

RSC Advances

DOI

2021

Aspergillus oryzae Biosynthetic Platform for de Novo Iridoid Production

Yali Duan, Jiawei Liu, Yun Du, Xiaolin Pei, Mu Li

Journal of Agricultural and Food Chemistry

DOI

2021

MrGcn5 is required for the mycotoxin production, sexual and asexual development in Monascus ruber

Jing Zhang, Jing Gao, Mu Li, Yanchun Shao, Fusheng Chen

Food Bioscience

DOI

2020

Engineering Saccharomyces cerevisiae Coculture Platform for the Production of Flavonoids

Yun Du, Binrui Yang, Zhiqiang Yi, Lanlan Hu, Mu Li

Journal of Agricultural and Food Chemistry

DOI

2020

Enhancement of Monascus yellow pigments production by activating the cAMP signalling pathway in Monascus purpureus HJ11

Jiawei Liu, Yun Du, Hongmin Ma, Xiaolin Pei, Mu Li

Microbial Cell Factories

DOI

2020

Monasone Naphthoquinone Biosynthesis and Resistance in Monascus Fungi

Mu Li, Lijing Kang, Xiaoli Ding, Jiao Liu, Qingpei Liu, Yanchun Shao, István Molnár, Fusheng Chen

mBio

DOI

2017

Screening, purification, and characterization of a novel organic solvent-tolerant esterase, Lip2, from Monascus purpureus strain M7

Lijing Kang, Zi-Tong Meng, Hu Chen, Yan Zhang, Hai-Lun Guo, Qing Li, Mu Li

Extremophiles

DOI

2017

Orange, red, yellow: biosynthesis of azaphilone pigments in Monascus fungi

Wanping Chen, Runfa Chen, Qingpei Liu, Yi He, Kun He, Xiaoli Ding, Lijing Kang, Xiaoxiao Catherine Guo, Nana Xie, Youxiang Zhou, Yuanyuan Lu, Russell John Cox, István Molnár, Mu Li, Yanchun Shao, Fusheng Chen

Chemical Science

DOI

2016

Conversion of a Monascus ruber esterase into a lipase by disrupting a salt bridge

Zi-Tong Meng, Hu Chen, Yan Zhang, Hai-Lun Guo, Mu Li

Journal of Molecular Catalysis B Enzymatic

DOI

2016

Cloning, expression and characterization of a novel cold-active and organic solvent-tolerant esterase from Monascus ruber M7

Hai-Lun Guo, Yan Zhang, Yanchun Shao, Wanping Chen, Fusheng Chen, Mu Li

Extremophiles

DOI

2016

Cloning and characterization of a novel lipase from Stenotrophomonas maltophilia GS11: The first member of a new bacterial lipase family XVI

Mu Li, Li-Rong Yang, Gang Xu, Jianping Wu

Journal of Biotechnology

DOI

2016

A novel thermostable and organic solvent-tolerant lipase from Xanthomonas oryzae pv. oryzae YB103: screening, purification and characterization

Qiurun Mo, Aili Liu, Hai-Lun Guo, Yan Zhang, Mu Li

Extremophiles

DOI

2016

Highly diastereoselective acylation of l-menthol by a lipase from Stenotrophomonas maltophilia CGMCC 4254

Mu Li, Li-Rong Yang, Gang Xu, Jianping Wu

Biochemical Engineering Journal

DOI

2015

Edible Filamentous Fungi from the Species Monascus : Early Traditional Fermentations, Modern Molecular Biology, and Future Genomics

Wanping Chen, Yi He, Youxiang Zhou, Yanchun Shao, Yanli Feng, Mu Li, Fusheng Chen

Comprehensive Reviews in Food Science and Food Safety

DOI

2015

Inactivation of the global regulator LaeA in Monascus ruber results in a species-dependent response in sporulation and secondary metabolism

Qingpei Liu, Li Cai, Yanchun Shao, Youxiang Zhou, Mu Li, Xiaohong Wang, Fusheng Chen

Fungal Biology

DOI

2014

Introducing a salt bridge into the lipase of Stenotrophomonas maltophilia results in a very large increase in thermal stability

Jianping Wu, Mu Li, Yong Gui Zhou, Li-Rong Yang, Gang Xu

Biotechnology Letters

DOI

李牧

精选作品

期刊论文

转录因子MpSte12调控红曲菌生长与红曲色素合成的机制研究

Machine Learning-Guided Cofactor Engineering for Tunable Azaphilone Component Ratios in Monascus spp.

A Novel Angiotensin I-Converting Enzyme Inhibitory Pentapeptide from Red Mold Rice: Identification, Stability, In V i vo Antihypertensive Effects, and Underlying Mechanisms

Corrigendum to “Metabolic modulation of TCA cycle by S-nitrosylation in Monascus spp.” [Synthetic and Systems Biotechnol 12 (2026) 490–501]

Metabolic modulation of TCA cycle by S-nitrosylation in Monascus spp.

基于比较基因组学的红曲霉VeA、VelB生物信息学分析

Monaspin B, a Novel Cyclohexyl-furan from Cocultivation of Monascus purpureus and Aspergillus oryzae, Exhibits Potent Antileukemic Activity

The serine/threonine protein kinase MpSTE1 directly governs hyphal branching in Monascus spp.

Modular and Flexible Molecular Device for Simultaneous Cytosine and Adenine Base Editing at Random Genomic Loci in Filamentous Fungi

Engineered aldoxime dehydratase to enable the chemoenzymatic conversion of benzyl amines to aromatic nitriles

Versatile Strategy for the Construction of a Transcription Factor-Based Orthogonal Gene Expression Toolbox in Monascus spp

鉴定红曲菌中萘醌响应基因提高红曲色素产率

Systematic Metabolic Engineering for the Production of Azaphilones in Monascus purpureus HJ11

Dynamic regulation of Monascus azaphilones biosynthesis by the binary MrPigE-MrPigF oxidoreductase system

An efficient microbial-based method for production of high-purity Monascus azaphilones pigments

Programing a cyanide-free transformation of aldehydes to nitriles and one-pot synthesis of amides through tandem chemo-enzymatic cascades

Aspergillus oryzae Biosynthetic Platform for de Novo Iridoid Production

MrGcn5 is required for the mycotoxin production, sexual and asexual development in Monascus ruber

Engineering Saccharomyces cerevisiae Coculture Platform for the Production of Flavonoids

Enhancement of Monascus yellow pigments production by activating the cAMP signalling pathway in Monascus purpureus HJ11

Monasone Naphthoquinone Biosynthesis and Resistance in Monascus Fungi

Screening, purification, and characterization of a novel organic solvent-tolerant esterase, Lip2, from Monascus purpureus strain M7

Orange, red, yellow: biosynthesis of azaphilone pigments in Monascus fungi

Conversion of a Monascus ruber esterase into a lipase by disrupting a salt bridge

Cloning, expression and characterization of a novel cold-active and organic solvent-tolerant esterase from Monascus ruber M7

Cloning and characterization of a novel lipase from Stenotrophomonas maltophilia GS11: The first member of a new bacterial lipase family XVI

A novel thermostable and organic solvent-tolerant lipase from Xanthomonas oryzae pv. oryzae YB103: screening, purification and characterization

Highly diastereoselective acylation of l-menthol by a lipase from Stenotrophomonas maltophilia CGMCC 4254

Edible Filamentous Fungi from the Species Monascus : Early Traditional Fermentations, Modern Molecular Biology, and Future Genomics

Inactivation of the global regulator LaeA in Monascus ruber results in a species-dependent response in sporulation and secondary metabolism

Introducing a salt bridge into the lipase of Stenotrophomonas maltophilia results in a very large increase in thermal stability

会议论文

红曲菌聚酮合酶的合成机制

预印本

Metabolic reprogramming driven by mpSte11A deletion redirects carbon flux toward overproduction of Monascus pigments in Monascus ruber

研究方向