百晓学者学者目录

韩怡静

副教授,鲁东大学

精选作品

期刊论文

2026

Identification of a CREB-regulated transcription coactivator (CRTC) in Crassostrea gigas and its role in regulating melanin production

张金海,Nan Gao,Xuexin Yu,Wenhao Yang,Yulu Jiang,Chen Liu,Yijing Han,Yaqiong Liu,Xiaotong Wang

International Journal of Biological Macromolecules

2026

Abalone genomics reveals an ancient asymmetry axis and the multifunctionality of the mantle

Xiaotong Wang, Chunhui Li, Peidong Xin, Meiwei Zhang, Baoyu Huang, T. Chen, Siyi Li, Yijing Han, Lei Wei, Xuekai Zhang, Yaqiong Liu, Chenglong Zhu, Wenjie Xu, Zhiyong Yue, Wenshi Xue, Wenchao Yu, Peng Zhang, Lingling Li, Mengqiang Yuan, Deyang Tian, Jiyan Qi, Qiang Qiu, Kun Wang, Ximing Guo, Chenguang Feng

Science Advances

2026

The significant regulatory role of cytochrome P450 in the innate immune response of the Zhikong scallop (Chlamys farreri)

Yue Zhao, Xuewei Qu, Xuan Ding, Guoshun Ren, Vengatesen Thiyagarajan, Xiaolong Chu, Fengchen Liu, Ying-Run Liu, Yijing Han, Baoyu Huang, X Y Wang

Developmental & Comparative Immunology

2026

The immune enhancement strategies of Strongylocentrotus intermedius in response to different immunomodulators

Yaqiong Liu, Yulu Jiang, Nan Gao, Sifan Chen, Wenhao Yang, 张锦海, Yijing Han, Xiaotong Wang

Comparative Biochemistry and Physiology Part D Genomics and Proteomics

2026

Region-specific metabolomics reveals the mechanisms underlying melanin synthesis in Pacific oyster (Crassostrea gigas) mantle

Xingda Jia, Xiaochen Zhang, Haoyu Zhang, Yijing Han, Xiaotong Wang

Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology

2026

miR-182-5p affects melanin formation in Crassostrea gigas by regulating the MITF gene

Yan Li, Wenhao Wang, Wan Liu, Jialin Zhao, Xiaochen Zhang, Yijing Han, Haoyu Zhang, Xingda Jia, Junsong YangLi, Xiaotong Wang

Comparative Biochemistry and Physiology Part D Genomics and Proteomics

2026

Transcriptomic analysis of key sex-differentiation genes in wild Atrina pectinata from Changdao, China

Cong Wei, Yan Gao, Lufei Yang, Deyan Hu, Hongce Song, Junsong YangLi, Yijing Han, Xiaotong Wang, Wei Chen

Israeli Journal of Aquaculture - Bamidgeh

2026

The identification of SiMyD88 confirms the presence of a functional TLR-MyD88-IRAK signaling axis in the sea urchin Strongylocentrotus intermedius

Haikun Zhang, Xuewei Qu, Xuan Ding, Guoshun Ren, Vengatesen Thiyagarajan, Xiaolong Chu, Fengchen Liu, Jie Cui, Yifan Qu, Yaqiong Liu, Yijing Han, Baoyu Huang, Xiaotong Wang

Fish & Shellfish Immunology

2025

microRNA-183-5p通过调控MITF基因影响长牡蛎黑色素形成

刘万,张晓臣,赵春暖,张浩瑜,杨李俊淞,韩怡静,高雁,王晓通

《海洋科学》

2025

Signaling pathways underlying extracellular trap formation induced by Vibrio alginolyticus in Strongylocentrotus intermedius

Haoyu Zhang, Wei Chen, Xiaochen Zhang, Yijing Han, Wan Liu, Yan Li, Xiaona Wang, Xiaona Wang, Deyang Tian, Dong Xu, Weizhong Wang, Junsong YangLi, Yaqiong Liu, Xiaotong Wang, Xiaotong Wang

Comparative Biochemistry and Physiology Part D Genomics and Proteomics

2025

Electroporation-based CRISPR/Cas9 Gene Editing in Haliotis Discus Hannai

Chen Liu, Dianzhi Yao, Yulu Jiang, Chuncao Huo, Jinhai Zhang, Suyuan Yi, Wenhao Yang, Yijing Han, Yaqiong Liu, Xiaotong Wang

Marine Biotechnology

2025

A newly identified homolog of scallop caspase-3/7 plays a pivotal role in the immunological response and orchestrates the induction of apoptosis

Jie Cui, Dianzhi Yao, Haikun Zhang, Yifan Qu, Xiaoxue Lin, Yaqiong Liu, Yijing Han, Baoyu Huang, Xiaotong Wang

Fish & Shellfish Immunology

2025

Two novel TRAF homologs are implicated in the immunological response and interact with IRAK in the Zhikong scallop (Chlamys farreri)

Jiwen Chen, Wei Chen, Yifan Qu, Xiaoxue Lin, Haikun Zhang, Jilv Ma, Jie Cui, Fengchen Liu, Zhongyi Chu, Yue Zhao, Yabin Wang, Yaqiong Liu, Yijing Han, Baoyu Huang, Xiaotong Wang

Aquaculture

2025

Functional characterization of a molluscan executioner caspase in apoptosis and innate immunity

Jie Cui, Zi-Hao Zhang, Zhaoxi Zhang, Shuang Zhang, Haikun Zhang, Yifan Qu, Guoqing Yu, Yaqiong Liu, Yijing Han, Baoyu Huang, Xiaotong Wang

Fish & Shellfish Immunology

2025

Characterization of SiIκB confirms the existence of a conserved IκB–NF-κB regulatory mechanism in sea urchin Strongylocentrotus intermedius

Yifan Qu, Yan Gao, Jie Cui, Haikun Zhang, Fengchen Liu, Xiaoxue Lin, Zhongyi Chu, Yaqiong Liu, Yijing Han, Baoyu Huang, Xiaotong Wang

Fish & Shellfish Immunology

2025

Identification of a dual specificity protein phosphatase and its function in regulating innate immune signaling in Crassostrea gigas

Chuncao Huo, Yaqiong Liu, Wenhao Yang, Qianqian Jin, Chen Liu, Yulu Jiang, Jinhai Zhang, Yijing Han, Xiaotong Wang

Fish & Shellfish Immunology

2025

Effects of Vibrio alginolyticus on intestinal health and intestinal flora of sea urchin (Strongylocentrotus intermedius)

Xiaochen Zhang, Wei Chen, Haoyu Zhang, Yan Li, Yijing Han, Wan Liu, Yaqiong Liu, Xiaona Wang, Xiaona Wang, Xuekai Zhang, Deyang Tian, Xiaotong Wang, Xiaotong Wang

Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology

2025

Mechanism of Crassostrea gigas T-box Transcription Factor 2: Regulation by a Transcript Isoform of Microphthalmia-Associated Transcription Factor and Its Role in Cell Proliferation

Wenhao Yang, Jinhai Zhang, Yi-Biao Jiang, Chen Liu, Yijing Han, Yaqiong Liu, Xiaotong Wang

Marine Biotechnology

2025

The characterization of a novel IRF8-like homolog and its role in the immune modulation of the sea urchin Strongylocentrotus intermedius

Baoyu Huang, Yifan Qu, Haikun Zhang, Jilv Ma, Jiwen Chen, Jie Cui, Fengchen Liu, Zhongyi Chu, Yaqiong Liu, Yijing Han, Xiaotong Wang, Wenhao Wang

Fish & Shellfish Immunology

2024

长牡蛎Wnt5b基因的鉴定及在黑色素生成中的作用

霍春草,杨文豪,蔡帅,于涛,刘晨,张海坤,韩怡静,张国光,刘雅琼,王晓通

《海洋通报》

2024

Ocean acidification aggravates the toxicity of deltamethrin in Haliotis discus hannai: Insights from immune response, histopathology and physiological responses.

Xiao-Jing Lv, Qinyou Deng, Lizhu Chen, Xin Wang, Yijing Han, Gui-Qing Wu, Yongliang Liu, Hai-Yue Sun, Xuan Li, Jinxia He, Xiang-Quan Liu, Ding-Long Yang, Jian-Min Zhao

Aquatic Toxicology

2024

Nonylphenol displays immunotoxicity by triggering hemocyte extracellular traps in Manila clam via ROS burst, ERK pathway and glycolysis.

Xiao-Jing Lv, Yijing Han, Yong-Xue Li, Xin Wang, Tianyu Zhang, Xiao-Dan Wang, Qianqian Zhang, Ding-Long Yang, Jian-Min Zhao

Ecotoxicology and Environmental Safety

2024

Regulation of Biomineralization and Autophagy by the Stress-Sensing Transcription Factor CgRunx1 in Crassostrea gigas Under Daylight Ultraviolet B Radiation

Hongce Song, Meiyun Dong, Wenwen Xu, Chaoyi Xie, Yuxuan Zhang, Haifeng Huang, Kai Zhang, Yijing Han, Yaqiong Liu, Lei Wei, Xiaotong Wang

Marine Biotechnology

2024

Preliminary investigation on the effect of Vibrio splendidus stimulation on the intestinal flora of Strongylocentrotus intermedius

Xiaochen Zhang, Yan Li, Wan Liu, Haoyu Zhang, Yijing Han, Yaqiong Liu, Xiaotong Wang

Biochemical and Biophysical Research Communications

2024

Analysis of microbial communities on the coloured mantle surface of three common bivalves

Chaoyi Xie, Yijing Han, Meiyun Dong, Yuxuan Zhang, Hongce Song, Haifeng Huang, Haikun Zhang, Yaqiong Liu, Lei Wei, Xiaotong Wang

Aquaculture Reports

2024

Effects of ambient UVB light on Pacific oyster Crassostrea gigas mantle tissue based on multivariate data

Hongce Song, Chaoyi Xie, Meiyun Dong, Yuxuan Zhang, Haifeng Huang, Yijing Han, Yaqiong Liu, Lei Wei, Xiaotong Wang

Ecotoxicology and Environmental Safety

2024

Identification of a T-box transcription factor TBX2 and its negative regulatory role in melanin production in the Pacific oyster Crassostrea gigas

Wenhao Yang, Chen Liu, Yaqiong Liu, Nan Gao, Baoyu Huang, Yijing Han, Xiaotong Wang

International Journal of Biological Macromolecules

2024

A scallop IκB protein involved in innate immunity acts as a key regulator of NF-κB

Jiwen Chen, Yifan Qu, Juan Dong, Wenwen Xu, Yue Zhao, Jie Cui, Zhengjie Yu, Zihao Bao, Jilv Ma, Yijing Han, Yaqiong Liu, Baoyu Huang, Xiaotong Wang

Fish & Shellfish Immunology

2024

Molecular cloning and functional study of a Rel homologous gene in sea urchin Strongylocentrotus intermedius

Yifan Qu, Jie Cui, Jilv Ma, Jiwen Chen, Haikun Zhang, Yue Zhao, Zhengjie Yu, Zihao Bao, Yijing Han, Yaqiong Liu, Baoyu Huang, Xiaotong Wang

Fish & Shellfish Immunology

2024

Molluscan pleiotropic FADD involved in innate immune signaling and induces apoptosis

Jie Cui, Yifan Qu, Jilv Ma, Jiwen Chen, Yue Zhao, Zhengjie Yu, Zihao Bao, Yijing Han, Yaqiong Liu, Baoyu Huang, Xiaotong Wang

International Journal of Biological Macromolecules

2024

A newly identified scallop MyD88 interacts with TLR and functions in innate immunity

Baoyu Huang, Jilv Ma, Wenwen Xu, Jie Cui, Jiwen Chen, Yifan Qu, Yue Zhao, Yijing Han, Yaqiong Liu, Weizhong Wang, Xiaotong Wang

Fish & Shellfish Immunology

2024

IKK2 modulates the innate immune response of Zhikong scallop (Chlamys farreri) to bacterial and viral stimuli through the MyD88-dependent Toll-like receptor signaling pathway

Lingling Li, Jie Cui, Yifan Qu, Jilv Ma, Jiwen Chen, Yue Zhao, Yijing Han, Yaqiong Liu, Baoyu Huang, Xiaotong Wang

Aquaculture

2024

Molecular confirmation and functional study of signal transducer and activator of transcription genes in the Pacific oyster Crassostrea gigas

Jilv Ma, Jie Cui, Yifan Qu, Jiwen Chen, Yue Zhao, Yijing Han, Yaqiong Liu, Baoyu Huang, Xiaotong Wang

Fish & Shellfish Immunology

2023

基于特定序列的长牡蛎视黄酸反应元件预测

李言柯,徐晓莹,魏磊,黄宝玉,张美溦,韩怡静,刘雅琼,王晓梅,王晓通

《海洋通报》

2023

长牡蛎贝壳损伤后的再固着能力初探

胡乐彬,范妮妮,蔡帅,王晓梅,郑言鑫,魏磊,黄宝玉,刘雅琼,韩怡静,王晓娜,孙宗哲,张美溦,王晓通

《海洋通报》

2023

长牡蛎贝壳不同部位的几丁质提取及鉴定

李迈,唐菊艳,蔡帅,袁孟强,魏磊,黄宝玉,刘雅琼,韩怡静,王晓娜,蔡忠强,张美溦,王晓通

《海洋通报》

2023

中间球海胆人工育苗附着基改良及不同规格种苗养殖效果的比较

冯纪虎,田德阳,袁廷柱,袁孟强,郭文剑,王晓娜,黄宝玉,魏磊,刘雅琼,张美溦,韩怡静,张学开,王晓通

《海洋通报》

2023

In vitro study of deltamethrin-induced extracellular traps in hemocytes of Ruditapes philippinarum.

Yijing Han, Qian-Qian Zhang, Lizhu Chen, Jian-Min Zhao, Ding-Long Yang

Ecotoxicology and Environmental Safety

2023

A novel TBK1/IKKϵ is involved in immune response and interacts with MyD88 and MAVS in the scallop Chlamys farreri

Wen-jing Liu, Jilv Ma, Jiwen Chen, Bao-Yu Huang, Feng-Cheng Liu, Ling-Ling Li, Nini Fan, Fangshu Li, Yan-Xin Zheng, Xue-Kai Zhang, Xiao-Na Wang, Xiao-Mei Wang, Lei Wei, Ya-Qiong Liu, Mei-Wei Zhang, Yijing Han, Xiao-Tong Wang

Frontiers in Immunology

2023

Identification and characterization of gonadotropin-releasing hormone (GnRH) in Zhikong scallop Chlamys farreri during gonadal development

Juyan Tang, Mengqiang Yuan, Jia Wang, Qianqian Li, Baoyu Huang, Wei Lei, Yaqiong Liu, Yijing Han, Xuekai Zhang, Xiaona Wang, Xiaona Wang, Meiwei Zhang, Xiaotong Wang, Xiaotong Wang

Frontiers in Physiology

2022

皱纹盘鲍肽聚糖识别蛋白在免疫防御中的作用

陈钰莹,韩怡静,刘相全,何金霞,杨顶珑

《渔业科学进展》

2022

Scallop NEMO interacts with IKK1 and regulates host innate immunity against PAMPs

Ling-Ling Li, Wen-jing Liu, Fangshu Li, Bao-Yu Huang, Qianqian Liu, Xiao-Na Wang, Xiuxiu Sang, Juan Dong, Jilv Ma, Jiwen Chen, Lei Wei, Ya-Qiong Liu, Mei-Wei Zhang, Yijing Han, Xiao-Tong Wang

Aquaculture

2022

Transcriptional expression analysis reveals multiple effects of nonylphenol exposure on scallop immune system.

Qianqian Liu, Fangshu Li, Wen-jing Liu, Bao-Yu Huang, Ling-Ling Li, Xiao-Na Wang, Xiuxiu Sang, Juan Dong, Jilv Ma, Jiwen Chen, Lei Wei, Ya-Qiong Liu, Mei-Wei Zhang, Yijing Han, Xiao-Tong Wang

Fish and Shellfish Immunology

2022

CfIRF8-like interacts with the TBK1/IKKε family protein and regulates host antiviral innate immunity.

Fangshu Li, Wen-jing Liu, Jiwen Chen, Bao-Yu Huang, Yan-Xin Zheng, Jilv Ma, Shuai Cai, Ling-Ling Li, Feng-Cheng Liu, Xiao-Na Wang, Lei Wei, Ya-Qiong Liu, Mei-Wei Zhang, Yijing Han, Xue-Kai Zhang, Xiao-Tong Wang

Fish and Shellfish Immunology

2021

Mitochondria are essential for antibacterial extracellular trap formation mediated by zymosan in hemocytes of Ruditapes philippinarum.

Yijing Han, Qian-Qian Zhang, Lizhu Chen, Ding-Long Yang, Jian-Min Zhao

Developmental and Comparative Immunology

2021

Identification, antibacterial activities and action mode of two macins from manila clam Venerupis philippinarum.

Rui Xue, Yijing Han, Fan Li, Lizhu Chen, Ding-Long Yang, Jian-Min Zhao

Fish and Shellfish Immunology

2021

14-3-3ζ and 14-3-3ε are involved in innate immune responses in Pacific abalone (Haliotis discus hannai).

Rui Xue, Ding-Long Yang, Yijing Han, Qinyou Deng, Xin Wang, Xiang-Quan Liu, Jian-Min Zhao

Developmental and Comparative Immunology

2021

Antibacterial activity and mechanism of a type-I ubiquitin from the clam Ruditapes philippinarum.

Yijing Han, Lizhu Chen, Ding-Long Yang

Journal of Invertebrate Pathology

2021

Antimicrobial Defensin and DNA Traps in Manila Clam Ruditapes philippinarum: Implications for Their Roles in Immune Responses

Yijing Han, Gege Hu, Yuying Chen, Lizhu Chen, Daode Yu, Qian-Qian Zhang, Ding-Long Yang

Frontiers in Marine Science

2020

Hemocyte extracellular traps of Manila clam Ruditapes philippinarum: Production characteristics and antibacterial effects.

Yijing Han, Lizhu Chen, Qian-Qian Zhang, Daode Yu, Ding-Long Yang, Jian-Min Zhao

Developmental and Comparative Immunology

2020

Antibacterial activities and mechanisms of action of a defensin from manila clam Ruditapes philippinarum.

Chengjie Lv, Yijing Han, Ding-Long Yang, Jian-Min Zhao, Chun-Lin Wang, Chang-Kao Mu

Fish and Shellfish Immunology

2019

Molecular cloning and characterization of FADD from the manila clam Ruditapes philippinarum

Gege Hu, Yijing Han, Ding-Long Yang, Ruiwen Cao, Qing Wang, Hui Liu, Zhi-Jun Dong, Xiao-Li Zhang, Qian-Qian Zhang, Jian-Min Zhao

Fish and Shellfish Immunology

2019

A peptidoglycan recognition protein involved in immune recognition and immune defenses in Ruditapes philippinarum

Ding-Long Yang, Yijing Han, Yongliang Liu, Ruiwen Cao, Qing Wang, Zhi-Jun Dong, Hui Liu, Xiao-Li Zhang, Qian-Qian Zhang, Jian-Min Zhao

Fish and Shellfish Immunology

2019

Scavenger receptor class B type I (SR‐BI) in Ruditapes philippinarum: A versatile receptor with multiple functions

Ding-Long Yang, Yijing Han, Lizhu Chen, Yongliang Liu, Ruiwen Cao, Qing Wang, Jian-Min Zhao

Fish and Shellfish Immunology

2019

A macin identified from Venerupis philippinarum: Investigation on antibacterial activities and action mode.

Ding-Long Yang, Yijing Han, Lizhu Chen, Ruiwen Cao, Qing Wang, Zhi-Jun Dong, Hui Liu, Xiao-Li Zhang, Qian-Qian Zhang, Jian-Min Zhao

Fish and Shellfish Immunology

2019

A bactericidal permeability-increasing protein (BPI) from manila clam Ruditapes philippinarum: Investigation on the antibacterial activities and antibacterial action mode.

Ding-Long Yang, Yijing Han, Lizhu Chen, Ruiwen Cao, Qing Wang, Zhi-Jun Dong, Hui Liu, Xiao-Li Zhang, Qian-Qian Zhang, Jian-Min Zhao

Fish and Shellfish Immunology

2018

Two macrophage migration inhibitory factors (MIFs) from the clam Ruditapes philippinarum: Molecular characterization, localization and enzymatic activities

Dan Wang, Ding-Long Yang, Qing Wang, Ye Zhao, Cheng-Hua Li, Qianyu Wei, Yijing Han, Jian-Min Zhao

Fish and Shellfish Immunology

会议论文

2024

灿烂弧菌对虾夷马粪海胆肠道菌群影响的初步研究

张晓臣,李艳,刘万,张浩瑜,韩怡静,王晓通

《中国动物学会·中国海洋湖沼学会贝类学分会换届大会暨第二十一次全国贝类学术讨论会摘要集》

2024

长牡蛎外套膜三层褶皱的功能分化以及与壳色形成的关系

李迈,唐菊艳,袁孟强,黄宝玉,刘雅琼,魏磊,韩怡静,张学开,王晓娜,于国旭,桑秀秀,范妮妮,蔡帅,郑言鑫,张美溦,王晓通

《中国动物学会·中国海洋湖沼学会贝类学分会换届大会暨第二十一次全国贝类学术讨论会》

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