束敏峰｜复旦大学｜学者主页

2026

An IGF2BP3-dependent metabolic circuit governs macrophage recruitment and immunosuppression in glioblastoma

Weiwei Dai, Ruotong Tian, Ming Whye Chong, Jin Li, Bowen Yin, Zhuoyang Fan, Shasha Bian, Minfeng Shu

Cell Reports

2026

TAF15-mediated m5C modification of MTHFD2 RNA reveals a novel therapeutic target for IDH mutant gliomas

Ruixin Wu, Li Zhang, Peter Jih Cheng Wong, Chunming Sun, Yuan Feng, Xiaoyu Wang, Minjie Fu, Jinsen Zhang, Fufang Qiu, Xi Chen, Zhen Fan, Minfeng Shu, Wei Hua

Biomarker Research

DOI

2026

RBFOX2 suppresses NETosis and glioma growth via 5hmC-dependent PDGFB decay

Xi Chen, Weiwei Dai, Hanlin Wang, Jianing Fang, Bowen Yin, Changwei Liu, Yuling Chen (438010), Ruixin Wu, Yiheng Cai, Shasha Bian, Rihan Hai, Jin Li, Yiqian Zhu, Minfeng Shu

Cell Reports

DOI

2026

A novel risk model incorporating MMP9, TLR8, and LILRB2 drives neutrophil extracellular trap formation and promotes immune evasion in glioma

Yuxuan Luan, Jianing Fang, Jiani Li, Xi Chen, Jin Li, Rosamaria Pennisi, Liqin Huang, Maria Kalamvoki, Maria Teresa Sciortino, Yong Meng, Yilin Wang, Minfeng Shu

International Immunopharmacology

DOI

2025

Integrative analysis of crotonylation-associated genes reveals prognostic and therapeutic targets in gliomas

Bowen Yin, Zhuoyang Fan, Panpan Yu, Jin Li, Yilin Wang, Minfeng Shu

Frontiers in Oncology

DOI

2025

Integrated Analysis of Cuproptosis Regulators Reveals Prognostic Significance and Therapeutic Targets in IDH1 Mutant Glioma

Yuxuan Luan, Yong Meng, Chunming Sun, Rui‐Xin Wu, Qimeng Chang, Yilin Wang, Minfeng Shu

MedComm – Future Medicine

DOI

2024

双链RNA通过激活PKR/eIF2α通路抑制恶性胶质瘤生长和迁移

燕群，卞莎莎，束敏峰

《复旦学报(医学版)》

2024

HSV-1-induced N6-methyladenosine reprogramming via ICP0-mediated suppression of METTL14 potentiates oncolytic activity in glioma

Yuling Chen, Shasha Bian, Jiamei Zhang, Yuxuan Luan, Bowen Yin, Weiwei Dai, Hanlin Wang, Xi Chen, Yan Dong, Yiheng Cai, Ruitao Dong, Liubing Yu, Minfeng Shu

Cell Reports

DOI

2024

Comprehensive analysis of paraspeckle-associated gene modules unveils prognostic signatures and immunological relevance in multi-cancers

Zhuoyang Fan, Bowen Yin, Xiaochen Chen, Guowei Yang, Wei Zhang, Xiaodan Ye, Hong Han, Ming Li, Minfeng Shu, Rong Liu

Discover Oncology

DOI

2024

NSUN5/TET2-directed chromatin-associated RNA modification of 5-methylcytosine to 5-hydroxymethylcytosine governs glioma immune evasion

Ruixin Wu, Chunming Sun, Xi Chen, Runyue Yang, Yuxuan Luan, Xiang Zhao, Panpan Yu, Rongkui Luo, Yingyong Hou, Ruotong Tian, Shasha Bian, Yuli Li, Yinghua Dong, Qian Liu, Weiwei Dai, Zhuoyang Fan, Rucheng Yan, Binyang Pan, Siheng Feng, Jing Wu, Fangzhen Chen, Changle Yang, Hanlin Wang, Haochen Dai, Minfeng Shu

Proceedings of the National Academy of Sciences

DOI

2024

Sublethal heat treatment enhances lactic acid uptake in macrophages via MCT1, leading to reduced paraspeckle formation and a subsequent decrease in macrophage pyroptosis

Zhuoyang Fan, Guowei Yang, Rongkui Luo, Xu-Dong Qu, Xiaodan Ye, Jianhua Wang, Zhiping Yan, Minfeng Shu, Wei Zhang, Rong Liu

Frontiers in Immunology

DOI

2024

Overcoming therapeutic resistance in oncolytic herpes virotherapy by targeting IGF2BP3-induced NETosis in malignant glioma

Weiwei Dai, Ruotong Tian, Liubing Yu, Shasha Bian, Yuling Chen, Bowen Yin, Yuxuan Luan, Siqi Chen, Zhuoyang Fan, Rucheng Yan, Xin Pan, Yingyong Hou, Rong Li, Juxiang Chen, Minfeng Shu

Nature Communications

DOI

2023

IDH1 mutation impairs antiviral response and potentiates oncolytic virotherapy in glioma

Xueqin Chen, Jun Liu, Yuqin Li, Yuequan Zeng, Fang Wang, Zexiong Cheng, Hao Duan, Guopeng Pan, Shangqi Yang, Yuling Chen, Qing Li, Xi Hua Shen, Ying Li, Zixi Qin, Jiahong Chen, Youwei Huang, Xiangyu Wang, Yuli Lu, Minfeng Shu, Yubo Zhang, Guo‐Cai Wang, Kai Li, Xi Lin, Fan Xing, Haipeng Zhang

Nature Communications

DOI

2023

Comprehensive Analysis of Ferroptosis Regulators with Regard to PD-L1 and Immune Infiltration in Low-Grade Glioma

Yuxuan Luan, Yuling Chen, Yilin Wang, Minfeng Shu

International Journal of Molecular Sciences

DOI

2023

Melittin inhibits tumor cell migration and enhances cisplatin sensitivity by suppressing IL‐17 signaling pathway gene LCN2 in castration‐resistant prostate cancer

Rucheng Yan, Weiwei Dai, Yuanshen Mao, Guopeng Yu, Wenfeng Li, Minfeng Shu, Bin Xu

The Prostate

DOI

2023

The Tick-Borne Pathogens: An Overview of China’s Situation

Yuxuan Luan, Jing-min Gou, Dongjie Zhong, Li Ma, Chuansong Yin, Minfeng Shu, Guangyuan Liu, Qing Lin

Acta Parasitologica

DOI

2022

Therapeutic targeting m6A-guided miR-146a-5p signaling contributes to the melittin-induced selective suppression of bladder cancer

Rucheng Yan, Weiwei Dai, Rui‐Xin Wu, Houbao Huang, Minfeng Shu

Cancer Letters

DOI

2022

Circadian Regulation Patterns With Distinct Immune Landscapes in Gliomas Aid in the Development of a Risk Model to Predict Prognosis and Therapeutic Response

Ruotong Tian, Yimin Li, Minfeng Shu

Frontiers in Immunology

DOI

2021

miR‐221/222 suppression induced by activation of the cAMP/PKA/CREB1 pathway is required for cAMP‐induced bidirectional differentiation of glioma cells

Qian Liu, Ruotong Tian, Panpan Yu, Minfeng Shu

FEBS Letters

DOI

2021

Hypoxia blocks ferroptosis of hepatocellular carcinoma via suppression of METTL14 triggered YTHDF2‐dependent silencing of SLC7A11

Zhuoyang Fan, Guowei Yang, Wei Zhang, Qian Liu, Guangqin Liu, Pingping Liu, Ligang Xu, Jianhua Wang, Zhiping Yan, Hong Han, Rong Liu, Minfeng Shu

Journal of Cellular and Molecular Medicine

DOI

2021

Identification and Validation of an Immune-Associated RNA-Binding Proteins Signature to Predict Clinical Outcomes and Therapeutic Responses in Glioma Patients

Ruotong Tian, Yimin Li, Qian Liu, Minfeng Shu

Cancers

DOI

2021

METTL3/IGF2BP1/CD47 contributes to the sublethal heat treatment induced mesenchymal transition in HCC

Zhuoyang Fan, Yang Gao, Wei Zhang, Guowei Yang, Pingping Liu, Ligang Xu, Jianhua Wang, Zhiping Yan, Hong Han, Rong Liu, Minfeng Shu

Biochemical and Biophysical Research Communications

DOI

2015

Transcriptional upregulation of microtubule-associated protein 2 is involved in the protein kinase A-induced decrease in the invasiveness of glioma cells.

Yu-Xi Zhou, Si-Han Wu, Chao-Feng Liang, Yuan Lin, Yan Zou, Kai Li, Bingzheng Lu, Minfeng Shu, Yi-Jun Huang, Wenbo Zhu, Z. Kang, Dong-Hui Xu, Jun Hu, Guangmei Yan

Neuro-Oncology

DOI

2015

Role of activating transcription factor 3 in the synthesis of latency-associated transcript and maintenance of herpes simplex virus 1 in latent state in ganglia

Minfeng Shu, Te Du, G. Zhou, B. Roizman

Proceedings of the National Academy of Sciences of the United States of America

DOI

2015

Tristetraprolin Recruits the Herpes Simplex Virion Host Shutoff RNase to AU-Rich Elements in Stress Response mRNAs To Enable Their Cleavage

Minfeng Shu, B. Taddeo, B. Roizman

Journal of Virology

DOI

2013

The Nuclear-Cytoplasmic Shuttling of Virion Host Shutoff RNase Is Enabled by pUL47 and an Embedded Nuclear Export Signal and Defines the Sites of Degradation of AU-Rich and Stable Cellular mRNAs

Minfeng Shu, B. Taddeo, B. Roizman

Journal of Virology

DOI

2013

Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein

Minfeng Shu, B. Taddeo, Wei-Ran Zhang, B. Roizman

Proceedings of the National Academy of Sciences of the United States of America

DOI

2013

Alphaxalone inhibits growth, migration and invasion of rat C6 malignant glioma cells.

Hua-Wei Sun, Xiaoke Zheng, Yue-Han Zhou, Wenbo Zhu, Yanqiu Ou, Minfeng Shu, Xiu-Ren Gao, Tian-Dong Leng, P. Qiu, Guangmei Yan

Steroids

DOI

2012

MicroRNA 335 Is Required for Differentiation of Malignant Glioma Cells Induced by Activation of cAMP/Protein Kinase A Pathway

Minfeng Shu, Yue-Han Zhou, Wenbo Zhu, Hai-Peng Zhang, Si-Han Wu, Jing-Kao Chen, Guangmei Yan

Molecular Pharmacology

DOI

2012

MiR-135a functions as a selective killer of malignant glioma

Si-Han Wu, Yuan Lin, Dong-Hui Xu, Jing-Kao Chen, Minfeng Shu, Yu-Wei Zhou, Wei-Guo Zhu, Xinwen Su, P. Qiu, Guangmei Yan

Oncogene

DOI

2011

米诺环素抑制MPP+诱导的PC12细胞凋亡和线粒体功能损伤

乐亮，李晶洁，黎仕锋，朱文博，束敏峰，苏兴文，邱鹏新，颜光美

《中国病理生理杂志》

2011

Targeting oncogenic miR-335 inhibits growth and invasion of malignant astrocytoma cells

Minfeng Shu, Xiaoke Zheng, Si-Han Wu, Hui-Min Lu, Tian-Dong Leng, Wenbo Zhu, Yue-Han Zhou, Yanqiu Ou, Xi Lin, Yuan Lin, Dong-Hui Xu, Yu-Xi Zhou, Guangmei Yan

Molecular Cancer

DOI

2011

Activation of a pro‐survival pathway IL‐6/JAK2/STAT3 contributes to glial fibrillary acidic protein induction during the cholera toxin‐induced differentiation of C6 malignant glioma cells

Minfeng Shu, Yu-Xi Zhou, Wenbo Zhu, Si-Han Wu, Xiaoke Zheng, Guangmei Yan

Molecular Oncology

DOI

2009

Hypoxia‐inducible factor‐1α blocks differentiation of malignant gliomas

Hui-Min Lu, Yan Li, Minfeng Shu, Jianjun Tang, Yi-Jun Huang, Yu-Xi Zhou, Ying-Jie Liang, Guangmei Yan

The FEBS Journal

DOI

2009

Anesthetic pentobarbital inhibits proliferation and migration of malignant glioma cells.

Jun Xie, Yan Li, Yi-Jun Huang, P. Qiu, Minfeng Shu, Wenbo Zhu, Yanqiu Ou, Guangmei Yan

Cancer Letters

DOI

束敏峰

精选作品

期刊论文

An IGF2BP3-dependent metabolic circuit governs macrophage recruitment and immunosuppression in glioblastoma

TAF15-mediated m5C modification of MTHFD2 RNA reveals a novel therapeutic target for IDH mutant gliomas

RBFOX2 suppresses NETosis and glioma growth via 5hmC-dependent PDGFB decay

A novel risk model incorporating MMP9, TLR8, and LILRB2 drives neutrophil extracellular trap formation and promotes immune evasion in glioma

Integrative analysis of crotonylation-associated genes reveals prognostic and therapeutic targets in gliomas

Integrated Analysis of Cuproptosis Regulators Reveals Prognostic Significance and Therapeutic Targets in IDH1 Mutant Glioma

双链RNA通过激活PKR/eIF2α通路抑制恶性胶质瘤生长和迁移

HSV-1-induced N6-methyladenosine reprogramming via ICP0-mediated suppression of METTL14 potentiates oncolytic activity in glioma

Comprehensive analysis of paraspeckle-associated gene modules unveils prognostic signatures and immunological relevance in multi-cancers

NSUN5/TET2-directed chromatin-associated RNA modification of 5-methylcytosine to 5-hydroxymethylcytosine governs glioma immune evasion

Sublethal heat treatment enhances lactic acid uptake in macrophages via MCT1, leading to reduced paraspeckle formation and a subsequent decrease in macrophage pyroptosis

Overcoming therapeutic resistance in oncolytic herpes virotherapy by targeting IGF2BP3-induced NETosis in malignant glioma

IDH1 mutation impairs antiviral response and potentiates oncolytic virotherapy in glioma

Comprehensive Analysis of Ferroptosis Regulators with Regard to PD-L1 and Immune Infiltration in Low-Grade Glioma

Melittin inhibits tumor cell migration and enhances cisplatin sensitivity by suppressing IL‐17 signaling pathway gene LCN2 in castration‐resistant prostate cancer

The Tick-Borne Pathogens: An Overview of China’s Situation

Therapeutic targeting m6A-guided miR-146a-5p signaling contributes to the melittin-induced selective suppression of bladder cancer

Circadian Regulation Patterns With Distinct Immune Landscapes in Gliomas Aid in the Development of a Risk Model to Predict Prognosis and Therapeutic Response

miR‐221/222 suppression induced by activation of the cAMP/PKA/CREB1 pathway is required for cAMP‐induced bidirectional differentiation of glioma cells

Hypoxia blocks ferroptosis of hepatocellular carcinoma via suppression of METTL14 triggered YTHDF2‐dependent silencing of SLC7A11

Identification and Validation of an Immune-Associated RNA-Binding Proteins Signature to Predict Clinical Outcomes and Therapeutic Responses in Glioma Patients

METTL3/IGF2BP1/CD47 contributes to the sublethal heat treatment induced mesenchymal transition in HCC

Transcriptional upregulation of microtubule-associated protein 2 is involved in the protein kinase A-induced decrease in the invasiveness of glioma cells.

Role of activating transcription factor 3 in the synthesis of latency-associated transcript and maintenance of herpes simplex virus 1 in latent state in ganglia

Tristetraprolin Recruits the Herpes Simplex Virion Host Shutoff RNase to AU-Rich Elements in Stress Response mRNAs To Enable Their Cleavage

The Nuclear-Cytoplasmic Shuttling of Virion Host Shutoff RNase Is Enabled by pUL47 and an Embedded Nuclear Export Signal and Defines the Sites of Degradation of AU-Rich and Stable Cellular mRNAs

Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein

Alphaxalone inhibits growth, migration and invasion of rat C6 malignant glioma cells.

MicroRNA 335 Is Required for Differentiation of Malignant Glioma Cells Induced by Activation of cAMP/Protein Kinase A Pathway

MiR-135a functions as a selective killer of malignant glioma

米诺环素抑制MPP+诱导的PC12细胞凋亡和线粒体功能损伤

Targeting oncogenic miR-335 inhibits growth and invasion of malignant astrocytoma cells

Activation of a pro‐survival pathway IL‐6/JAK2/STAT3 contributes to glial fibrillary acidic protein induction during the cholera toxin‐induced differentiation of C6 malignant glioma cells

Hypoxia‐inducible factor‐1α blocks differentiation of malignant gliomas

Anesthetic pentobarbital inhibits proliferation and migration of malignant glioma cells.