温泉｜中国科学技术大学｜学者主页

2026

Multi-timescale motor circuit dynamics underlie adaptive and efficient exploratory behavior.

Pinjie Li, Heng Zhang, Jiaqi Wang, Yifan Su, Louis Tao, Quan Wen

Current Biology

DOI

2026

A Structural Principle for Macroscopic Neural Dynamics Correlations

Qi-Hang Wu, Quan Wen, Ci-Rong Liu

bioRxiv

DOI

2026

Serotonergic modulation of motor subspace dynamics drives a sleep-independent quiescent state

Kexin Qi, Yuming Chai, Guodong Tan, Daguang Li, Quan Wen

eLife

DOI

2026

Author response: Serotonergic modulation of motor subspace dynamics drives a sleep-independent quiescent state

Kexin Qi, Yuming Chai, Guodong Tan, Daguang Li, Quan Wen

DOI

2025

The geometry and dimensionality of brain-wide activity

Zezhen Wang, Weihao Mai, Yuming Chai, Kexin Qi, Hongtai Ren, Chen Shen, Shiwu Zhang, Guodong Tan, Yu Hu, Quan Wen

eLife

DOI

2025

TurboID-based proximity labeling identifies novel germline proteins that maintain E granule integrity and small RNA homeostasis in C. elegans

Kun Li, Xue-Zhu Feng, Ke Wang, Xiao-Na Huang, Liang Liu, Chaoyue Yan, Xin-Ya Huang, Cheng-Ming Zhu, Quan Wen, Shou-Hong Guang, Xiangyang Chen

Science China Life Sciences

DOI

2025

Author response: The Geometry and Dimensionality of Brain-wide Activity

Zezhen Wang, Weihao Mai, Yuming Chai, Kexin Qi, Hongtai Ren, Chen Shen, Shiwu Zhang, Guodong Tan, Yu Hu, Quan Wen

DOI

2025

From Pixels to Views: Learning Angular-Aware and Physics-Consistent Representations for Light Field Microscopy

Feng He, Guodong Tan, Qiankun Li, Jun Yu, Quan Wen

neural information processing systems

DOI

2024

Hierarchical behavior control by a single class of interneurons

Jing Huo, Tianqi Xu, Qi Liu, Mahiber Polat, Sandeep Kumar, Xiaoqian Zhang, Andrew M Leifer, Quan Wen

bioRxiv

DOI

2023

乙酰胆碱门控氯离子通道受体突变影响秀丽线虫运动学和运动状态转换

玛伊拜尔·普拉提，熊荣康，霍菁，温泉

《生物化学与生物物理进展》

2023

虚拟视觉刺激引起幼年斑马鱼捕食行为放弃的研究

张翔宇，柴宇明，齐珂心，温泉

《生物化学与生物物理进展》

2023

All-optical interrogation of brain-wide activity in freely swimming larval zebrafish

Yuming Chai, Kexin Qi, Yubin Wu, Daguang Li, Guodong Tan, Yuqi Guo, Jun Chu, Yu Mu, Chen Shen, Quan Wen

iScience

DOI

2023

A tonically active master neuron modulates mutually exclusive motor states at two timescales

Jun Meng, Tosif Ahamed, Bin Yu, W. Hung, Sonia Ei Mouridi, Zezhen Wang, Yong-Ning Zhang, Quan Wen, T. Boulin, Shangbang Gao, M. Zhen

bioRxiv

DOI

2023

The scale-invariant covariance spectrum of 1 brain-wide activity

Zezhen Wang, Wei-Hao Mai, Yuming Chai, Kexin Qi, Hong-Tai Ren, Chen Shen, Shi-Wu Zhang, Yu Hu, Quan Wen

2023

Bidirectional near-infrared regulation of motor behavior using orthogonal emissive upconversion nanoparticles

Jingxuan Guo, Lili Chen, Feihong Xiong, Yongning Zhang, Yongning Zhang, Ruipeng Wang, Xuefei Zhang, Quan Wen, Shangbang Gao, Yan Zhang, Yan Zhang

Nanoscale

DOI

2022

趋流行为下斑马鱼幼鱼的全脑成像（英文）

吴宇斌，张仁昌，李大光，齐珂心，柴宇明，沈忱，司光伟，温泉

《生物化学与生物物理进展》

2022

A descending interneuron with depolarized resting membrane potential controls C. elegans motor states

Jun Meng, Tosif Ahamed2a, Yuan-Yuan Bin, W. Hung, Sonia El Mouridi, Alice Leclercq-Blondel, M. Gendrel, Zezhen Wang, Li-Li Chen, Quan Wen, T. Boulin, Shangbang Gao, M. Zhen

2022

Extrasynaptic signaling enables an asymmetric juvenile motor circuit to produce symmetric undulation

Yangning Lu, Tosif Ahamed, Ben Mulcahy, Jun Meng, Daniel K. Witvliet, Sihui Asuka Guan, Douglas P. Holmyard, Wesley Hung, Quan Wen, Andrew D. Chisholm, Aravinthan D. T. Samuel, Mei Zhen

Current Biology

DOI

2022

C. elegans: Sensing the low-frequency profile of amplitude-modulated ultrasound

Tianyang Long, Linzhou Xie, Mayibaier Pulati, Quan Wen, Xiasheng Guo, Dong Zhang

Ultrasonics

DOI

2022

Rapid detection and recognition of whole brain activity in a freely behaving Caenorhabditis elegans

Yuxiang Wu, Shang Wu, Xin Wang, Chengtian Lang, Quanshi Zhang, Quan Wen, Tianqi Xu

PLoS Computational Biology

DOI

2021

Nonthermal and reversible control of neuronal signaling and behavior by midinfrared stimulation

Xi Liu, Z. Qiao, Yuming Chai, Zhi Zhu, Kai-Jie Wu, Wen-Liang Ji, Da-Guang Li, Yujie Xiao, L. Mao, Chao Chang, Quan Wen, Bo Song, You-Sheng Shu

Proceedings of the National Academy of Sciences of the United States of America

DOI

2020

Sensory Glia Detect Repulsive Odorants and Drive Olfactory Adaptation

Duo Duan, Hu Zhang, Xiaomin Yue, Yuedan Fan, Yadan Xue, Jiajie Shao, Gang Ding, Du Chen, Shitian Li, Hankui Cheng, Xiaoyan Zhang, Wenjuan Zou, Jia Liu, Jian Zhao, Linmei Wang, Bingzhen Zhao, Zhiping Wang, Suhong Xu, Quan Wen, Jie Liu, Shumin Duan, Lijun Kang

Neuron

DOI

2020

Flexible motor sequence generation during stereotyped escape responses

Yuan Wang, Xiaoqian Zhang, Xin Qi, Wesley Hung, Jeremy Florman, Jing Huo, Tianqi Xu, Yu Xie, Mark J. Alkema, Mei Zhen, Quan Wen

eLife

DOI

2020

Author response: Flexible motor sequence generation during stereotyped escape responses

Yuan Wang, Xiaoqian Zhang, Xin Qi, Wesley Hung, Jeremy Florman, Jing Huo, Tianqi Xu, Yu Xie, Mark J. Alkema, Mei Zhen, Quan Wen

DOI

2018

Visual intensity ratio modulates operant learning responses in larval zebrafish

Wenbin Yang, Yutong Meng, Danyang Li, Quan Wen

bioRxiv

DOI

2018

Caenorhabditis elegans excitatory ventral cord motor neurons derive rhythm for body undulation

Quan Wen, Shangbang Gao, Mei Zhen

Philosophical Transactions of the Royal Society B Biological Sciences

DOI

2018

Descending pathway facilitates undulatory wave propagation in Caenorhabditis elegans through gap junctions

Tianqi Xu, Jing Huo, Shuai Shao, Michelle D. Po, Taizo Kawano, Yangning Lu, Min Wu, Mei Zhen, Quan Wen

Proceedings of the National Academy of Sciences

DOI

2017

Author response: Rapid whole brain imaging of neural activity in freely behaving larval zebrafish (Danio rerio)

Lin Cong, Zeguan Wang, Yuming Chai, Wei Hang, Chun-Feng Shang, Wenbin Yang, Lu Bai, Jiu-Lin Du, Kai Wang, Quan Wen

DOI

2016

An extrasynaptic GABAergic signal modulates a pattern of forward movement in Caenorhabditis elegans

Yu Shen, Quan Wen, He Liu, Connie S. Zhong, Yuqi Qin, Gareth P. Harris, Taizo Kawano, Min Wu, Tianqi Xu, Aravinthan D. T. Samuel, Yun Zhang

eLife

DOI

2016

Author response: An extrasynaptic GABAergic signal modulates a pattern of forward movement in Caenorhabditis elegans

Yu Shen, Quan Wen, He Liu, Connie S. Zhong, Yuqi Qin, Gareth P. Harris, Taizo Kawano, Min Wu, Tianqi Xu, Aravinthan D. T. Samuel, Yun Zhang

DOI

2014

Dynamic Encoding of Perception, Memory, and Movement in a C. elegans Chemotaxis Circuit

Linjiao Luo, Quan Wen, Jing Ren, Michael Hendricks, Marc H Gershow, Yuqi Qin, Joel S. F. Greenwood, Edward R. Soucy, Mason Klein, Heidi Kay Smith, Ana C. Calvo, Daniel A. Colón‐Ramos, Aravinthan D. T. Samuel, Yun Zhang

Neuron

DOI

2012

Proprioceptive coupling within motor neurons drives C. elegans forward locomotion

Quan Wen, Michelle D. Po, Elizabeth Hulme, Sway Chen, Xinyu Liu, S. Kwok, Marc H. Gershow, Andrew M Leifer, Victoria Butler, C. Fang-Yen, Taizo Kawano, W. Schafer, G. Whitesides, M. Wyart, D. Chklovskii, M. Zhen, Aravinthan D. T. Samuel

Neuron

DOI

精选作品

期刊论文

Multi-timescale motor circuit dynamics underlie adaptive and efficient exploratory behavior.

A Structural Principle for Macroscopic Neural Dynamics Correlations

Serotonergic modulation of motor subspace dynamics drives a sleep-independent quiescent state

Author response: Serotonergic modulation of motor subspace dynamics drives a sleep-independent quiescent state

The geometry and dimensionality of brain-wide activity

TurboID-based proximity labeling identifies novel germline proteins that maintain E granule integrity and small RNA homeostasis in C. elegans

Author response: The Geometry and Dimensionality of Brain-wide Activity

From Pixels to Views: Learning Angular-Aware and Physics-Consistent Representations for Light Field Microscopy

Hierarchical behavior control by a single class of interneurons

乙酰胆碱门控氯离子通道受体突变影响秀丽线虫运动学和运动状态转换

虚拟视觉刺激引起幼年斑马鱼捕食行为放弃的研究

All-optical interrogation of brain-wide activity in freely swimming larval zebrafish

A tonically active master neuron modulates mutually exclusive motor states at two timescales

The scale-invariant covariance spectrum of 1 brain-wide activity

Bidirectional near-infrared regulation of motor behavior using orthogonal emissive upconversion nanoparticles

趋流行为下斑马鱼幼鱼的全脑成像（英文）

A descending interneuron with depolarized resting membrane potential controls C. elegans motor states

Extrasynaptic signaling enables an asymmetric juvenile motor circuit to produce symmetric undulation

C. elegans: Sensing the low-frequency profile of amplitude-modulated ultrasound

Rapid detection and recognition of whole brain activity in a freely behaving Caenorhabditis elegans

Nonthermal and reversible control of neuronal signaling and behavior by midinfrared stimulation

Sensory Glia Detect Repulsive Odorants and Drive Olfactory Adaptation

Flexible motor sequence generation during stereotyped escape responses

Author response: Flexible motor sequence generation during stereotyped escape responses

Visual intensity ratio modulates operant learning responses in larval zebrafish

Caenorhabditis elegans excitatory ventral cord motor neurons derive rhythm for body undulation

Descending pathway facilitates undulatory wave propagation in Caenorhabditis elegans through gap junctions

Author response: Rapid whole brain imaging of neural activity in freely behaving larval zebrafish (Danio rerio)

An extrasynaptic GABAergic signal modulates a pattern of forward movement in Caenorhabditis elegans

Author response: An extrasynaptic GABAergic signal modulates a pattern of forward movement in Caenorhabditis elegans

Dynamic Encoding of Perception, Memory, and Movement in a C. elegans Chemotaxis Circuit

Proprioceptive coupling within motor neurons drives C. elegans forward locomotion

会议论文

Robust and Flexible Motor Control during C.elegans Avoidance Behavior

The thermotaxis behaviours of C.elegans

预印本

Mesoscopic SCAPE Microscope with a Rescanned, Super-oblique Illumination Plane

书籍章节

Optically Monitoring and Manipulating Brain and Behavior in C. elegans

研究方向