余旭芬｜复旦大学｜学者主页

期刊论文

2026

Development of A10P3C, an isoform-selective inhibitor of EGLN2, for targeting breast cancer

Qian Liang, Huimin Zhu, Ban-Chieh Huang, Tzu-Kuan Lin, Yayoi Adachi, Ying Xue, Chengheng Liao, Xiaodong Lv, Xufen Yu, Lee‐Wei Yang, Xijuan Liu, Qing Hua Zhang

Proceedings of the National Academy of Sciences

DOI

2026

RIMTAC: A Novel Degrader Design Platform by Indirect VHL-Recruitment via RIPK1

Chang Shen, HD Sun, Ruining Li, Raghupathi Mutyala, Xinjian Tian, Chaoqun Huang, Jinglei Hu, Jie An, Lin Li, Tao Zhang, Xufen Yu, Bo Zhao, Mingyan Zhu, Yudao Shen

Journal of Medicinal Chemistry

DOI

2026

Unique Cysteine-Directed Covalent Inhibition of PRMT1 Suppresses Breast Tumorigenesis

Min Shao, Ruining Li, J B Hu, Wenjie Xi, Raghupathi Mutyala, Lulu Guan, Chaoqun Huang, Renhong Sun, Xiaobao Yang, 靳博, Bo Zhao, Er‐Jun Hao, Zhimin Zhang, Lin Li, Xufen Yu, Mingyan Zhu, Yudao Shen

Journal of Medicinal Chemistry

DOI

2026

Targeted Degradation of Prolyl Hydroxylase Domain Enzyme 1 (PHD1) as a Novel Therapeutic Strategy for Acetaminophen-Induced Acute Liver Injury

Huahua Su, Yuting Li, Ting Xie, Chaoqun Huang, J Z Liu, Aning Wu, Jin Wang, Jianpin Xiang, Xijuan Liu, Wei Chen, Xufen Yu

Journal of Medicinal Chemistry

DOI

2025

Corrigendum to “Design, synthesis, and biological evaluation of novel BTK-targeting proteolysis targeting chimeras (PROTACs) with enhanced pharmacokinetic properties” [Eur. J. Med. Chem. 289 (2025) 117420]

Ying‐Hung Lin, Jing Liu, Xinjian Tian, Jin Wang, Huahua Su, Jianpin Xiang, Tao Cao, Yonghui Wang, Qiong Xie, Xufen Yu

European Journal of Medicinal Chemistry

DOI

2025

Design, synthesis, and biological evaluation of novel BTK-targeting proteolysis targeting chimeras (PROTACs) with enhanced pharmacokinetic properties

Ying‐Hung Lin, Jing Liu, Xinjian Tian, Jin Wang, Huahua Su, Jianpin Xiang, Tao Cao, Yonghui Wang, Qiong Xie, Xufen Yu

European Journal of Medicinal Chemistry

DOI

2023

Discovery of novel BTK PROTACs with improved metabolic stability via linker rigidification strategy

Song Chen, Zhendong Chen, Lixue Lu, Yunpeng Zhao, Ronghui Zhou, Qiong Xie, Yongzhi Shu, Jun Lin, Xufen Yu, Yonghui Wang

European Journal of Medicinal Chemistry

DOI

书籍章节

2024

Advancing proteolysis targeting chimeras toward clinical drug developments

Xinjian Tian, Chaoqun Huang, Lin Yin, Xufen Yu

Elsevier eBooks

DOI

余旭芬

精选作品

期刊论文

Development of A10P3C, an isoform-selective inhibitor of EGLN2, for targeting breast cancer

RIMTAC: A Novel Degrader Design Platform by Indirect VHL-Recruitment via RIPK1

Unique Cysteine-Directed Covalent Inhibition of PRMT1 Suppresses Breast Tumorigenesis

Targeted Degradation of Prolyl Hydroxylase Domain Enzyme 1 (PHD1) as a Novel Therapeutic Strategy for Acetaminophen-Induced Acute Liver Injury

Corrigendum to “Design, synthesis, and biological evaluation of novel BTK-targeting proteolysis targeting chimeras (PROTACs) with enhanced pharmacokinetic properties” [Eur. J. Med. Chem. 289 (2025) 117420]

Design, synthesis, and biological evaluation of novel BTK-targeting proteolysis targeting chimeras (PROTACs) with enhanced pharmacokinetic properties

Discovery of novel BTK PROTACs with improved metabolic stability via linker rigidification strategy

书籍章节

Advancing proteolysis targeting chimeras toward clinical drug developments

研究方向