张昌浩｜延边大学｜学者主页

2026

Chemical constituents of Lespedeza davurica auct. non (Laxm.) Schindl.: V. N. Vassil. and their chemotaxonomic significance

Ze-Ming Wu, Qiong Wu, Xinyao Li, Yan-zheng Piao, Jing-Lin Piao, Mengwei Gao, Wei Liu, Ni-Nuo Ma, Changhao Zhang, Li-Li Jin

Biochemical Systematics and Ecology

DOI

2026

Bioactive compounds from A. dahurica attenuate LPS-induced inflammation via dual inhibition of MAPK and NF-κB signaling pathways.

Yue Zhang, Nan Wu, Xiongjie Yin, Y. Piao, Mengwei Gao, Jing-Lin Piao, Xin-Yao Li, Changhao Zhang, Li-Li Jin

Journal of Ethnopharmacology

DOI

2026

Research progress of curcumin and its derivatives as anti-inflammatory agents: From molecular mechanism to clinical application.

Nan Wu, Yue Zhang, Chengyu Cui, Chong-lu Sun, Zhixiang Cui, Hui Li, Junyi Jin, Mingjing Zhao, Xiongjie Yin, Li-Li Jin, Changhao Zhang

European journal of medicinal chemistry

DOI

2025

提高抗菌肽抗酶解稳定性的结构修饰策略研究进展

姜淑元，张昌浩，王陶然

《中国药理学与毒理学杂志》

2025

理心通脉颗粒指纹图谱的建立及化学模式识别分析

王茜颖，张洪铭，陈冬梅，徐雅娟，孙影，解生旭，张昌浩

《特产研究》

2025

乡村振兴背景下基于五改模式培养医药学复合型人才

李辉，赵洺婧，孙崇皓，尹雄杰，金莉莉，张昌浩

《农业与技术》

DOI

2025

The chemical composition of the stem bark of Picea jezoensis var. komarovii and its significance in chemotaxonomy

Mengwei Gao, Yue Zhang, Y. Piao, Lele Xu, Qiong Wu, Xiongjie Yin, Sihong Wang, Xinchun Yu, Changhao Zhang, Li-Li Jin

Biochemical Systematics and Ecology

DOI

2025

Research and development of natural product Salidroside: Pharmacology, total synthesis and structural modifications.

Mingjing Zhao, Nan Wu, Y. Piao, Chong-lu Sun, Junyi Jin, Chengyu Cui, Peng Du, Xiongjie Yin, Li-Li Jin, Changhao Zhang

European journal of medicinal chemistry

DOI

2025

Chemical constituents from Silene firma and their chemotaxonomic significance

Liang Sun, Jinling Zhang, Na Li, Changhao Zhang

Biochemical Systematics and Ecology

DOI

2025

Structural modification, total synthesis, and biological activity of natural product piperine: A review

Nan Wu, Xiongjie Yin, Chengyu Cui, Mingjing Zhao, Chong-lu Sun, Li-Li Jin, Changhao Zhang

Journal of Functional Foods

DOI

2025

Curcumin derivatives as ferroptosis inducers: design, synthesis and anti breast cancer activity evaluation.

Nan Wu, Yue Zhang, Xiongjie Yin, Peng Du, Y. Piao, Jiu-Zhen Zhao, Jing Zhu, Zheshan Quan, Cheng‐Zhu Wu, Li-Li Jin, Changhao Zhang

Bioorganic & Medicinal Chemistry

DOI

2024

Chemical constituents of Acer tegmentosum Maxim and their chemotaxonomic significance

Junyi Jin, Xiongjie Yin, Nan Wu, Chong-lu Sun, Mingjing Zhao, Sihong Wang, Qingwei Jiang, Li-Li Jin, Changhao Zhang

Biochemical Systematics and Ecology

DOI

2024

Chemical constituents from Alnus mandshurica and their chemotaxonomic significance

Chengyu Cui, Nan Wu, Xiongjie Yin, Mingjing Zhao, Chong-lu Sun, Sihong Wang, Jingyang Zhang, Li-Li Jin, Changhao Zhang

Biochemical Systematics and Ecology

DOI

2024

Chemical constituents from Cortex Moutan and their chemotaxonomic significance

Peng Du, Nan Wu, Xiongjie Yin, Chengyu Cui, Junyi Jin, Sihong Wang, Li-Li Jin, Changhao Zhang

Biochemical Systematics and Ecology

DOI

2024

Synthesis and biological evaluation of panaxadiol ester derivatives possessing pyrazole and pyrrole moiety as HIF-1α inibitors

Ye-Fang Lu, Chuang Liu, Juan Ma, Hu‐Ri Piao, Changhao Zhang, Xuejun Jin, Cheng Hua Jin

Fitoterapia

DOI

2023

基于网络药理学探讨青楷槭的抗弓形虫作用机制

屈金燕，王珈亿，杜鹏，于洪鹏，全星雨，张昌浩

《延边大学医学学报》

2023

基于网络药理学方法研究东北桤木的抗弓形虫作用机制

杜鹏，赵洺婧，孙崇皓，崔诚愈，金莉莉，张昌浩

《延边大学医学学报》

2023

紫花槭化合物抗败血症的网络药理学研究

尹雄杰，孙崇皓，赵洺婧，金君怡，金莉莉，张昌浩

《延边大学医学学报》

2023

基于网络药理学探讨东北桤木的抗肿瘤作用机制

全星雨，邬楠，尹雄杰，金莉莉，张昌浩

《延边大学医学学报》

2023

基于网络药理学的青楷槭抗败血症作用及其机制研究

于洪鹏，王珈亿，杜鹏，屈金燕，全星雨，张昌浩

《延边大学医学学报》

2023

智慧课堂教学模式在药物化学教学中的探索与实践

田玉顺，张昌浩

《延边大学医学学报》

2023

Recent Advances in Research on Active Compounds Against Hepatic Fibrosis

Chuang Liu, Siqi Li, Changhao Zhang, Cheng Hua Jin

Current Medicinal Chemistry

DOI

2023

Synthesis and antimicrobial activity evaluation of pyrazole derivatives containing the imidazo[2,1‐ b ][1,3,4]thiadiazole moiety

Jun‐Da Qi, Yuqing Meng, Jingxin Sun, Wan‐Xin Li, Hou‐Xiang Zhai, Changhao Zhang, Jishan Quan, Cheng Hua Jin

Archiv der Pharmazie

DOI

2022

常春藤皂苷元衍生物的合成和抗肿瘤活性

黄兴，张昌浩，邓浩，沈庆坤，郭红艳，全哲山，李志勇，金莉莉

《有机化学》

2022

基于网络药理学探讨水红花子抗肝硬化机制

杨涵，崔银峰，范忠义，朴燕，张昌浩，金莉莉

《延边大学学报(自然科学版)》

2022

长白鱼鳞云杉挥发性成分的气相色谱-质谱分析

徐乐乐，朴燕，尹雄杰，张昌浩，金莉莉

《延边大学学报(自然科学版)》

2022

青楷槭的化学成分研究

赵久朕，刘赛虎，刘若萱，王莹傲，崔银峰，张昌浩

《延边大学医学学报》

2022

高效液相色谱法测定青楷槭中红景天苷含量

李嘉琦，刘赛虎，刘若萱，王莹傲，金莉莉，张昌浩

《延边大学医学学报》

2022

Design, synthesis and biological evaluation of dehydroabietic acid derivative as potent vasodilatory agents

Dan Wu, Xiaoting Li, Qing‐Kun Shen, Runhui Zhang, Qian Xu, Xiao-Tong Sang, Xing Huang, Changhao Zhang, Zhe‐Shan Quan, Lihua Cao

Bioorganic Chemistry

DOI

2022

Anti-Toxoplasma gondii agent isolated from Orostachys malacophylla (Pallas) Fischer

Yan Piao, Lili Jin, Xu Cheng, Weifeng Yan, Changhao Zhang, Sihong Wang, Chunmei Jin

Experimental Parasitology

DOI

2022

Arctigenin: pharmacology, total synthesis, and progress in structure modification

Dan Wu, Lili Jin, Xing Huang, Hao Deng, Qing‐Kun Shen, Zhe‐Shan Quan, Changhao Zhang, Hong-Yan Guo

Journal of Enzyme Inhibition and Medicinal Chemistry

DOI

2022

Synthesis and evaluation of anticancer activity of quillaic acid derivatives: A cell cycle arrest and apoptosis inducer through NF-κB and MAPK pathways

Xing Huang, Changhao Zhang, Hao Deng, Dan Wu, Hong-Yan Guo, Jung Joon Lee, Fen‐Er Chen, Qing‐Kun Shen, Lili Jin, Zhe‐Shan Quan

Frontiers in Chemistry

DOI

2022

Synthesis and evaluation of in vitro and in vivo anti -Toxoplasma gondii activity of tetraoxane-substituted ursolic acid derivatives

Yalan Wang, Lili Jin, Xu Cheng, Weifeng Yan, Hao Deng, Qing‐Kun Shen, Zhe‐Shan Quan, Chunmei Jin, Changhao Zhang

Natural Product Research

DOI

2022

Research and Development of Natural Product Tanshinone I: Pharmacology, Total Synthesis, and Structure Modifications

Xing Huang, Lili Jin, Hao Deng, Dan Wu, Qing‐Kun Shen, Zhe‐Shan Quan, Changhao Zhang, Hongyan Guo

Frontiers in Pharmacology

DOI

2022

SAR Analysis of Heterocyclic Compounds with Monocyclic and Bicyclic Structures as Antifungal Agents

Yang Liu, Wen Bo Xu, Liang‐Peng Sun, Changhao Zhang, Cheng Hua Jin

ChemMedChem

DOI

2021

见血飞种壳化学成分的分离与鉴定

赵睿曦，王淼，刘婷，高慧媛，张昌浩

《沈阳药科大学学报》

DOI

2021

牡丹皮中丹皮酚提取工艺的研究

孙明月，赵婉君，全星宇，朴燕，金莉莉，张昌浩

《延边大学医学学报》

DOI

2021

桑黄多糖提取工艺的优化

徐艳，王珈亿，尹雄杰，金莉莉，刘杰，张昌浩

《延边大学医学学报》

DOI

2021

Semi-Synthesis and In Vitro Anti-Cancer Evaluation of Magnolol Derivatives

Xiaolong Sun, Meilin Zhu, Yiqun Dai, Hong-Mei Li, Bohan Li, Hui Ma, Changhao Zhang, Cheng‐Zhu Wu

Molecules

DOI

2020

龙胆化学成分和药理作用研究进展

潘旭，朱鹤云，张昌浩，冯波

《吉林医药学院学报》

2020

青楷槭提取物对脂多糖诱导的败血症小鼠的保护作用

邬楠，尹雄杰，金莉莉，张昌浩

《延边大学医学学报》

DOI

2020

青楷槭对小鼠急性毒性及体外抗弓形虫作用研究

尹雄杰，孙明月，徐艳，金春美，金莉莉，张昌浩

《延边大学医学学报》

DOI

2020

长白瑞香提取物的急性毒性及其体外抗弓形虫的研究

赵鹏宇，徐乐乐，金春美，张昌浩，金莉莉

《延边大学学报(自然科学版)》

DOI

2019

长白瑞香挥发性成分的GC- MS分析

赵鹏宇，朴燕，张昌浩，金莉莉

《延边大学医学学报》

DOI

2019

青楷子化学成分的研究进展

徐艳，金莉莉，张昌浩

《科技资讯》

DOI

2019

短梗五加的化学成分与药理作用研究进展

王丹，张昌浩

《科技资讯》

DOI

2019

一种含人参皂苷的中药润唇膏制备工艺研究

丁一凡，金莉莉，张昌浩，罗文莉

《科技资讯》

DOI

2018

木贼化学成分和药理作用研究近况

潘旭，张昌浩

《吉林医药学院学报》

2018

长白山地区野生与栽培蓝靛果原花青素含量的比较

尹雄杰，范忠义，金莉莉，张昌浩

《延边大学学报(自然科学版)》

2018

短梗五加乙酸乙酯提取物对败血症并发急性肝损伤模型小鼠的保护作用

朴燕，李镐，张昌浩

《延边大学医学学报》

2018

紫外分光光度法测定蓝靛果中原花青素含量

侯妍，张昌浩，范忠义，金莉莉

《延边大学医学学报》

2017

朝药草芍药的抗肿瘤活性成分研究

董玉娇，滕肖肖，张昌浩，全姬善，侯妍，金莉莉

《延边大学医学学报》

2017

国内植物多糖的研究及发展趋势

桑野，李晓光，张昌浩，冯波

《吉林医药学院学报》

2016

东北铁线莲化学成分研究

崔勇，金莉莉，金春梅，张昌浩

《延边大学医学学报》

2016

药剂学专业本科生药厂生产实习教学改革初探

金莉莉，张昌浩，朴明贯，金春梅，郭建鹏

《延边大学医学学报》

2016

Chemical Constituents of the Leaves of Juglans mandshurica

Dalei Yao, Mei Jin, Changhao Zhang, Jie Luo, Zhe Jiang, Mingshan Zheng, Jiongmo Cui, Gao Li

Chemistry of Natural Compounds

DOI

2015

药学专业本科生天然药物化学实验教学改革初探

张昌浩，安仁波，李镐，郑昌吉，朴惠善

《延边大学医学学报》

2015

槐果碱的体外抗弓形虫作用

张晓川，张昌浩，金莉莉，李婧美，金春梅

《延边大学医学学报》

2015

A new biflavonoid from the whole herb of Lepisorus ussuriensis

Jie Luo, Wei Ping Zhou, Shuo Cao, Mei Jin, Changhao Zhang, Xuejun Jin, Jiongmo Cui, Gao Li

Natural Product Research

DOI

2015

Chemical constituents from the aerial parts of Melandrium firmum

Changhao Zhang, Jie Luo, Tian Li, Yong Cui, Mei Jin, Dalei Yao, Mingshan Zheng, Zhenhua Lin, Jiongmo Cui, Gao Li

Archives of Pharmacal Research

DOI

2014

肾炎草化学成分研究

栗帅，金春实，李镐，姚大雷，张昌浩

《延边大学医学学报》

2014

红景天苷的全合成

张翼轩，张昌浩，赵春晖，付晓磊，陈艳华，李常，李镐，赵龙铉

《合成化学》

2014

A new phenyl glycoside from the aerial parts ofEquisetum hyemale

Mei Jin, Changhao Zhang, Tie Zheng, Dalei Yao, Shen Le, Jie Luo, Zhe Jiang, Juan Ma, Xuejun Jin, Jiongmo Cui, Jung Joon Lee, Gao Li

Natural Product Research

DOI

2013

血红铆钉菇子实体对人肝星状细胞LX-2和人肝癌细胞Hep G2增殖的影响

祝鹤鸣，吴艳玲，李雪，姚大雷，张昌浩，崔炯谟，李镐

《安徽农业科学》

2013

软枣猕猴桃根的化学成分研究

秦雪，张昌浩，姚大雷，崔炯谟，李镐

《延边大学医学学报》

2013

榆树茎皮的化学成分研究

金红兰，金美，张昌浩，罗杰，姚大雷，李镐

《延边大学医学学报》

2011

柞树皮对脂多糖和D-氨基半乳糖诱导败血症休克小鼠的保护作用

袁红艳，张晔，王丹，张昌浩，韩在刚，李镐，崔炯漠

《时珍国医国药》

2011

Chemical constituents of Acanthopanax sessiliflorus Rupr. et Maxim. Seem

Changhao Zhang

Journal of Medical Science Yanbian University

2007

枇杷叶高效液相指纹图谱研究

张昌浩，吴松吉，朱延萍，朴惠善

《时珍国医国药》

2005

东北铁线莲抗肿瘤活性成分的研究

张昌浩

《延边大学》

Chemical constituents of Parasenecio auriculatus (DC.) H. koyama and their chemotaxonomic significance

Y. Piao, Ze-Ming Wu, Yue Zhang, Qiong Wu, Jing-Lin Piao, Mengwei Gao, Fang Ye, Changhao Zhang, Li-Li Jin

Biochemical Systematics and Ecology

DOI

精选作品

期刊论文

Chemical constituents of Lespedeza davurica auct. non (Laxm.) Schindl.: V. N. Vassil. and their chemotaxonomic significance

Bioactive compounds from A. dahurica attenuate LPS-induced inflammation via dual inhibition of MAPK and NF-κB signaling pathways.

Research progress of curcumin and its derivatives as anti-inflammatory agents: From molecular mechanism to clinical application.

提高抗菌肽抗酶解稳定性的结构修饰策略研究进展

理心通脉颗粒指纹图谱的建立及化学模式识别分析

乡村振兴背景下基于五改模式培养医药学复合型人才

The chemical composition of the stem bark of Picea jezoensis var. komarovii and its significance in chemotaxonomy

Research and development of natural product Salidroside: Pharmacology, total synthesis and structural modifications.

Chemical constituents from Silene firma and their chemotaxonomic significance

Structural modification, total synthesis, and biological activity of natural product piperine: A review

Curcumin derivatives as ferroptosis inducers: design, synthesis and anti breast cancer activity evaluation.

Chemical constituents of Acer tegmentosum Maxim and their chemotaxonomic significance

Chemical constituents from Alnus mandshurica and their chemotaxonomic significance

Chemical constituents from Cortex Moutan and their chemotaxonomic significance

Synthesis and biological evaluation of panaxadiol ester derivatives possessing pyrazole and pyrrole moiety as HIF-1α inibitors

基于网络药理学探讨青楷槭的抗弓形虫作用机制

基于网络药理学方法研究东北桤木的抗弓形虫作用机制

紫花槭化合物抗败血症的网络药理学研究

基于网络药理学探讨东北桤木的抗肿瘤作用机制

基于网络药理学的青楷槭抗败血症作用及其机制研究

智慧课堂教学模式在药物化学教学中的探索与实践

Recent Advances in Research on Active Compounds Against Hepatic Fibrosis

Synthesis and antimicrobial activity evaluation of pyrazole derivatives containing the imidazo[2,1‐ b ][1,3,4]thiadiazole moiety

常春藤皂苷元衍生物的合成和抗肿瘤活性

基于网络药理学探讨水红花子抗肝硬化机制

长白鱼鳞云杉挥发性成分的气相色谱-质谱分析

青楷槭的化学成分研究

高效液相色谱法测定青楷槭中红景天苷含量

Design, synthesis and biological evaluation of dehydroabietic acid derivative as potent vasodilatory agents

Anti-Toxoplasma gondii agent isolated from Orostachys malacophylla (Pallas) Fischer

Arctigenin: pharmacology, total synthesis, and progress in structure modification

Synthesis and evaluation of anticancer activity of quillaic acid derivatives: A cell cycle arrest and apoptosis inducer through NF-κB and MAPK pathways

Synthesis and evaluation of in vitro and in vivo anti -Toxoplasma gondii activity of tetraoxane-substituted ursolic acid derivatives

Research and Development of Natural Product Tanshinone I: Pharmacology, Total Synthesis, and Structure Modifications

SAR Analysis of Heterocyclic Compounds with Monocyclic and Bicyclic Structures as Antifungal Agents

见血飞种壳化学成分的分离与鉴定

牡丹皮中丹皮酚提取工艺的研究

桑黄多糖提取工艺的优化

Semi-Synthesis and In Vitro Anti-Cancer Evaluation of Magnolol Derivatives

龙胆化学成分和药理作用研究进展

青楷槭提取物对脂多糖诱导的败血症小鼠的保护作用

青楷槭对小鼠急性毒性及体外抗弓形虫作用研究

长白瑞香提取物的急性毒性及其体外抗弓形虫的研究

长白瑞香挥发性成分的GC- MS分析

青楷子化学成分的研究进展

短梗五加的化学成分与药理作用研究进展

一种含人参皂苷的中药润唇膏制备工艺研究

木贼化学成分和药理作用研究近况

长白山地区野生与栽培蓝靛果原花青素含量的比较

短梗五加乙酸乙酯提取物对败血症并发急性肝损伤模型小鼠的保护作用

紫外分光光度法测定蓝靛果中原花青素含量

朝药草芍药的抗肿瘤活性成分研究

国内植物多糖的研究及发展趋势

东北铁线莲化学成分研究

药剂学专业本科生药厂生产实习教学改革初探

Chemical Constituents of the Leaves of Juglans mandshurica

药学专业本科生天然药物化学实验教学改革初探

槐果碱的体外抗弓形虫作用

A new biflavonoid from the whole herb of Lepisorus ussuriensis

Chemical constituents from the aerial parts of Melandrium firmum

肾炎草化学成分研究

红景天苷的全合成

A new phenyl glycoside from the aerial parts ofEquisetum hyemale

血红铆钉菇子实体对人肝星状细胞LX-2和人肝癌细胞Hep G2增殖的影响

软枣猕猴桃根的化学成分研究

榆树茎皮的化学成分研究

柞树皮对脂多糖和D-氨基半乳糖诱导败血症休克小鼠的保护作用

Chemical constituents of Acanthopanax sessiliflorus Rupr. et Maxim. Seem

枇杷叶高效液相指纹图谱研究

东北铁线莲抗肿瘤活性成分的研究

Chemical constituents of Parasenecio auriculatus (DC.) H. koyama and their chemotaxonomic significance

预印本

Cortex Moutan Chemical Constituents Suppress Tumor by Regulating Mmp-2 and Hif-1α Transporters

研究方向