吴锋｜南通大学｜学者主页

期刊论文

2026

Cobrotoxin mitigates neuroinflammation and cognitive impairment by suppressing CD8+ T cell–microglia interactions in male 5 × FAD mice

Zhe Li, Boyuan Tan, Kaikai Dong, Xinyue Yu, Sophia W. Zhang, Lin Luo, Wenjuan Yao, Zhenghong Qin, Feng Wu

Biochemical Pharmacology

DOI

2025

Verapamil modulates astrocytic glycolytic dysfunction via TXNIP inhibition in the hippocampus of 3 × Tg-AD mice

Wenhui Zhou, Xinyi Yin, Jiayue Huang, Li Fu, Hanshika Yadav, Wenjuan Yao, Dandan Chu, Feng Wu

Biochemical Pharmacology

DOI

2025

DSS-induced colitis exacerbates Alzheimer's pathology via neutrophil elastase and cathepsin B activation

Chong Tang, Jing Wang, Minglei Ge, Li Fu, Jiayue Huang, Hanshika Yadav, Jianhua Shi, Shichun Feng, Feng Wu

International Immunopharmacology

DOI

2025

Neutrophil glycolysis mediates colitis-induced exacerbation of Alzheimer's disease

Boyuan Tan, Jingjing Zhang, Kaikai Dong, Zhe Li, Xinyue Yu, Sophia W. Zhang, Lin luo, Wenjuan Yao, Feng Wu

International Immunopharmacology

DOI

2024

Mecp2 Deficiency in Peripheral Sensory Neuron Improves Cognitive Function by Enhancing Hippocampal Dendritic Spine Densities in Mice

Yuting Feng, Jingge Wang, Jun Liu, Yinwei Zhou, Ying Jiang, Wenhui Zhou, Feng Wu, Xing‐Jun Liu, Lin Luo

Cells

DOI

2024

Dual-specificity tyrosine phosphorylation-regulated kinase 1A promotes the inclusion of amyloid precursor protein exon 7

Dandan Chu, Leyi Lei, Shu Ping Gu, Fei Liu, Feng Wu

Biochemical Pharmacology

DOI

2023

Neuronal aerobic glycolysis exacerbates synapse loss in aging mice

Wenhui Zhou, Xingyue Yang, Huixia Wang, Wenjuan Yao, Dandan Chu, Feng Wu

Experimental Neurology

DOI

2023

Tau truncation in the pathogenesis of Alzheimer’s disease: a narrative review

Dandan Chu, Xingyue Yang, Jing Wang, Yan Zhou, Jin‐Hua Gu, Jin Miao, Feng Wu, Fei Liu

Neural Regeneration Research

DOI

2020

TP53-induced glycolysis and apoptosis regulator (TIGAR) ameliorates lysosomal damage in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-mediated mouse model of Parkinson’s disease

Jianbin Ge, Hongyan Lin, Jie Yang, QiQi Li, Jing-si Zhou, Zheng‐Hong Qin, Feng Wu

Toxicology Letters

DOI

2020

Poloxamer 188-mediated anti-inflammatory effect rescues cognitive deficits in paraquat and maneb-induced mouse model of Parkinson’s disease

Wenbin Ding, Hongyan Lin, Xin Hong, Dongliang Ji, Feng Wu

Toxicology

DOI

2019

Poloxamer 188 rescues MPTP-induced lysosomal membrane integrity impairment in cellular and mouse models of Parkinson's disease

Hongli Dong, Yuanyuan Qin, Yuyu Huang, Dongliang Ji, Feng Wu

Neurochemistry International

DOI

2019

Subacute to chronic Alzheimer-like alterations after controlled cortical impact in human tau transgenic mice

Yanchong Zhang, Feng Wu, Khalid Iqbal, Cheng‐Xin Gong, Wen Hui Hu, Fei Liu

Scientific Reports

DOI

2018

电针联合天麻素对阿尔茨海默病大鼠海马CA 1区沉默信息调节因子2同源蛋白1和过氧化物酶体增殖物激活受体γ辅激活子1 ɑ表达的影响

黄锐，吴锋，赵健，李怀斌，丁见，熊克仁

《针刺研究》

2018

不同强度电针对脑缺血大鼠海马CA2区Aβ蛋白和磷酸化Tau蛋白的表达影响

鲍睿，吴锋，缪化春，赵健，丁见，杨姗，李怀斌

《齐齐哈尔医学院学报》

2018

NADPH ameliorates MPTP-induced dopaminergic neurodegeneration through inhibiting p38MAPK activation

Jing-si Zhou, Zhou Zhu, Feng Wu, Ying Yin Zhou, Rui Sheng, Junchao Wu, Zheng‐Hong Qin

Acta Pharmacologica Sinica

DOI

2017

TDP-43 suppresses tau expression via promoting its mRNA instability

Jianlan Gu, Feng Wu, Wen Xu, Jianhua Shi, Wen Hui Hu, Nana Jin, Wei Qian, Xinglong Wang, Khalid Iqbal, Cheng‐Xin Gong, Fei Liu

Nucleic Acids Research

DOI

2016

Preventive effect of genetic knockdown and pharmacological blockade of CysLT1R on lipopolysaccharide (LPS)-induced memory deficit and neurotoxicity in vivo

Fang Chen, Arijit Ghosh, Feng Wu, Susu Tang, Mei Ying Hu, Hongbin Sun, Ling‐Yi Kong, Hao Hong

Brain Behavior and Immunity

DOI

2016

Montelukast ameliorates streptozotocin-induced cognitive impairment and neurotoxicity in mice

Chun Teng Zhang, Jingran Lin, Feng Wu, Arijit Ghosh, Su Su Tang, Mei Ying Hu, Yan Long, Hong Sun, Hao Hong

NeuroToxicology

DOI

2016

Z-guggulsterone negatively controls microglia-mediated neuroinflammation via blocking IκB-α–NF-κB signals

Chao Huang, Jili Wang, Xu Lu, Wenfeng Hu, Feng Wu, Bo Jiang, Yong Ling, Rongrong Yang, Wei Zhang

Neuroscience Letters

DOI

2015

α-突触核蛋白自噬性降解障碍在环境毒素鱼藤酮导致帕金森症中机制研究

吴锋

《苏州大学》

2014

自噬诱导剂海藻糖对帕金森症小鼠的治疗作用

吴锋，秦巨峰

《交通医学》

2014

Rotenone impairs autophagic flux and lysosomal functions in Parkinson’s disease

Feng Wu, Haidong Xu, J.-J. Guan, Yi‐Sheng Hou, Jin‐Hua Gu, Xuechu Zhen, Zheng‐Hong Qin

Neuroscience

DOI

2013

p38MAPK/p53-Mediated Bax induction contributes to neurons degeneration in rotenone-induced cellular and rat models of Parkinson’s disease

Feng Wu, Zhong Wang, Jin‐Hua Gu, Jianbin Ge, Zhong‐Qin Liang, Zheng‐Hong Qin

Neurochemistry International

DOI

预印本

2026

Dyrk1A promotes tau pathology and synaptic dysfunction in hTau transgenic mice

Chong Tang, Kaifeng Yao, Leyan Chen, Zhe Li, Jiaxin Sun, Chengxin Luo, Fei Liu, Feng Wu

SSRN Electronic Journal

DOI

吴锋

精选作品

期刊论文

Cobrotoxin mitigates neuroinflammation and cognitive impairment by suppressing CD8+ T cell–microglia interactions in male 5 × FAD mice

Verapamil modulates astrocytic glycolytic dysfunction via TXNIP inhibition in the hippocampus of 3 × Tg-AD mice

DSS-induced colitis exacerbates Alzheimer's pathology via neutrophil elastase and cathepsin B activation

Neutrophil glycolysis mediates colitis-induced exacerbation of Alzheimer's disease

Mecp2 Deficiency in Peripheral Sensory Neuron Improves Cognitive Function by Enhancing Hippocampal Dendritic Spine Densities in Mice

Dual-specificity tyrosine phosphorylation-regulated kinase 1A promotes the inclusion of amyloid precursor protein exon 7

Neuronal aerobic glycolysis exacerbates synapse loss in aging mice

Tau truncation in the pathogenesis of Alzheimer’s disease: a narrative review

TP53-induced glycolysis and apoptosis regulator (TIGAR) ameliorates lysosomal damage in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-mediated mouse model of Parkinson’s disease

Poloxamer 188-mediated anti-inflammatory effect rescues cognitive deficits in paraquat and maneb-induced mouse model of Parkinson’s disease

Poloxamer 188 rescues MPTP-induced lysosomal membrane integrity impairment in cellular and mouse models of Parkinson's disease

Subacute to chronic Alzheimer-like alterations after controlled cortical impact in human tau transgenic mice

电针联合天麻素对阿尔茨海默病大鼠海马CA 1区沉默信息调节因子2同源蛋白1和过氧化物酶体增殖物激活受体γ辅激活子1 ɑ表达的影响

不同强度电针对脑缺血大鼠海马CA2区Aβ蛋白和磷酸化Tau蛋白的表达影响

NADPH ameliorates MPTP-induced dopaminergic neurodegeneration through inhibiting p38MAPK activation

TDP-43 suppresses tau expression via promoting its mRNA instability

Preventive effect of genetic knockdown and pharmacological blockade of CysLT1R on lipopolysaccharide (LPS)-induced memory deficit and neurotoxicity in vivo

Montelukast ameliorates streptozotocin-induced cognitive impairment and neurotoxicity in mice

Z-guggulsterone negatively controls microglia-mediated neuroinflammation via blocking IκB-α–NF-κB signals

α-突触核蛋白自噬性降解障碍在环境毒素鱼藤酮导致帕金森症中机制研究

自噬诱导剂海藻糖对帕金森症小鼠的治疗作用

Rotenone impairs autophagic flux and lysosomal functions in Parkinson’s disease

p38MAPK/p53-Mediated Bax induction contributes to neurons degeneration in rotenone-induced cellular and rat models of Parkinson’s disease

预印本

Dyrk1A promotes tau pathology and synaptic dysfunction in hTau transgenic mice

研究方向