姚开泰｜南方医科大学｜学者主页

2024

Tumor-Derived EBV-miR-BART2-5p Promotes Nasopharyngeal Carcinoma Metastasis by Inducing Premetastatic Endothelial Cell Pyroptosis

Xingrui Chen, Qiqi Li, Xiaoyan Fu, Jike Li, Jun Deng, Qianbing Zhang, Mengying Qiu, Xiaoming Lyu, Linbo Cai, Hainan Li, Xin Li, Kai‐Tai Yao, Jiahong Wang, Zhongxi Huang, Liang Chen, Jiangyu Zhang, Dengke Li

Molecular Cancer Research

DOI

2023

Data from Epstein-Barr Virus Induces Lymphangiogenesis and Lympth Node Metastasis via Upregulation of VEGF-C in Nasopharyngeal Carcinoma

Dengke Li, Xingrui Chen, Lina Wang, Jiahong Wang, Yue-Ting Wen, Ziying Zhou, Ji-Ke Li, Jingxian Liu, Linbo Cai, Shui-Sheng Zhong, Xiaoming Lyu, Faleti Oluwasijibomi Damola, Min-Ying Li, Jingjing Zhang, Yu‐Mei Zeng, Qian-Li Wang, Qianbing Zhang, Hao Lyu, Xiaoyan Fu, Wei Wang, Xin Li, Zhongxi Huang, Kai‐Tai Yao

DOI

2022

Exosomal HMGA2 protein from EBV-positive NPC cells destroys vascular endothelial barriers and induces endothelial-to-mesenchymal transition to promote metastasis

Deng-Ke Li, Xing-Rui Chen, Lina Wang, Jiahong Wang, Ji-Ke Li, Ziying Zhou, Xin Li, Linbo Cai, Shui-Sheng Zhong, Jingjing Zhang, Yumei Zeng, Qianbing Zhang, Xiaoyan Fu, Xiaoming Lyu, Min-Ying Li, Zhongxi Huang, Kai‐Tai Yao

Cancer Gene Therapy

DOI

2021

Correction to: Casticin inhibits nasopharyngeal carcinoma growth by targeting phosphoinositide 3-kinase

Jingxian Liu, Jinghong Yang, Yuhe Hou, Zhenwei Zhu, Jie He, Hao Zhao, Xidong Ye, Dengke Li, Zhao‐Hui Wu, Zhongxi Huang, Bingtao Hao, Kai‐Tai Yao

Cancer Cell International

DOI

2020

A novel miR-200c/c-myc negative regulatory feedback loop is essential to the EMT process, CSC biology and drug sensitivity in nasopharyngeal cancer

Jing Yang, Si-Pei Wu, Wenjun Wang, Zhi-Ru Jin, Xiaobo Miao, Yue Wu, Deming Gou, Qiu‐Zhen Liu, Kai‐Tai Yao

Experimental Cell Research

DOI

2019

Casticin inhibits nasopharyngeal carcinoma growth by targeting phosphoinositide 3-kinase

Jingxian Liu, Jinghong Yang, Yuhe Hou, Zhenwei Zhu, Jie He, Hao Zhao, Xidong Ye, Dengke Li, Zhao‐Hui Wu, Zhongxi Huang, Bingtao Hao, Kai‐Tai Yao

Cancer Cell International

DOI

2019

Publisher Correction: NOS1 S-nitrosylates PTEN and inhibits autophagy in nasopharyngeal carcinoma cells

Lingqun Zhu, Linlin Li, Qianbing Zhang, Xiao Yang, Zhiwei Zou, Bingtao Hao, Francesco Maria Marincola, Zhengjun Liu, Zhuo Zhong, Meng Wang, Xiaoxuan Li, Qianli Wang, Keyi Li, Wenwen Gao, Kai‐Tai Yao, Qiuzhen Liu

Cell Death and Disease

DOI

2018

利用CRISPR/Cas9技术建立NOD/SCID/IL2Rγ-/-免疫缺陷小鼠（英文）

刘亚宸，陈渠，杨兴龙，汤清双，姚开泰，徐洋

《南方医科大学学报》

2018

A regulatory mutant on TRIM 26 conferring the risk of nasopharyngeal carcinoma by inducing low immune response

Xiaoming Lyu, Xiaowei Zhu, Manli Zhao, Xian‐Bo Zuo, Zhongxi Huang, Xiao Liu, Tao Jiang, Xuexi Yang, Xin Li, Xin Li, Xiaobing Long, Jian‐Guo Wang, Jin‐Bang Li, Mingyu Han, Shuang Wang, Tengfei Liu, Bo Zhang, Tao Sun, Zhi Cheng, Mo-Chang Qiu, Lei Dong, Lu Zheng, Long‐Cheng Zhang, Jiahong Wang, Gan‐Guan Wei, Kai‐Tai Yao, Qian Wang, Hou‐Feng Zheng, Xin Li, Xin Li

Cancer Medicine

DOI

2017

5T4-specific chimeric antigen receptor modification promotes the immune efficacy of cytokine-induced killer cells against nasopharyngeal carcinoma stem cell-like cells

Xueyang Guo, Hang Zheng, Weiren Luo, Qianbing Zhang, Jingxian Liu, Kai‐Tai Yao

Scientific Reports

DOI

2017

A novel three‑dimensional tumorsphere culture system for the efficient and low‑cost enrichment of cancer stem cells with natural polymers

Zhenwei Zhu, Lin Chen, Jing‐Xian Liu, Jun‐Wen Huang, Gang Wu, Yanfang Zheng, Kai‐Tai Yao

Experimental and Therapeutic Medicine

DOI

2017

NOS1 S-nitrosylates PTEN and inhibits autophagy in nasopharyngeal carcinoma cells

Lingqun Zhu, Linlin Li, Qianbing Zhang, Yang Xiao, Zhiwei Zou, Bingtao Hao, Francesco Maria Marincola, Zhengjun Liu, Zhuo Zhong, Meng Wang, Xiaoxuan Li, Qianli Wang, Keyi Li, Wenwen Gao, Kai‐Tai Yao, Qiuzhen Liu

Cell Death Discovery

DOI

2017

Klf4 reduces stemness phenotype, triggers mesenchymal-epithelial transition (MET)-like molecular changes, and prevents tumor progression in nasopharygeal carcinoma

Xiqing Li, Zhunlan Zhao, Xiaoling Zhang, Sheng Yang, Xia Lin, Xinglong Yang, Xiaolin Lin, Junwen Shi, Shengchun Wang, Wentao Zhao, Jing Li, Fei Gao, Mingyue Liu, Ning Ma, Weiren Luo, Kai‐Tai Yao, Yan Sun, Shengjun Xiao, Dong Xiao, Jun-Shuang Jia

Oncotarget

DOI

2016

SPLUNC1基因在人体组织中的表达分布特征

王爽，李文路，吕丽春，姚开泰

《南方医科大学学报》

2016

Higher methylation intensity induced by EBV LMP1 via NF-κB/DNMT3b signaling contributes to silencing of PTEN gene

Hong Peng, Yuxiang Chen, Pinggui Gong, Longmei Cai, Xiaoming Lyu, Qiang Jiang, Jianguo Wang, Juan Lü, Kai‐Tai Yao, Kunping Liu, Jinbang Li, Xin Li

Oncotarget

DOI

2016

The important role of the receptor for activated C kinase 1 (RACK1) in nasopharyngeal carcinoma progression

Hong Peng, Pinggui Gong, Jin-Bang Li, Longmei Cai, Le Yang, Yun-yi Liu, Kai‐Tai Yao, Xin Li

Journal of Translational Medicine

DOI

2015

Hes1 triggers epithelial-mesenchymal transition (EMT)-like cellular marker alterations and promotes invasion and metastasis of nasopharyngeal carcinoma by activating the PTEN/AKT pathway

Shengchun Wang, Xiaolin Lin, Huiyan Wang, Yujuan Qin, Lin Chen, Jing Li, Jun-Shuang Jia, Hong-Fen Shen, Sheng Yang, Raoying Xie, Fang Wei, Fei Gao, Xiaoxiang Rong, Jie Wu Yang, Wentao Zhao, Tingting Zhang, Junwen Shi, Kai‐Tai Yao, Weiren Luo, Yan Sun, Dong Xiao

Oncotarget

DOI

2015

Cytokine-induced killer cells efficiently kill stem-like cancer cells of nasopharyngeal carcinoma via the NKG2D-ligands recognition

Fang Wei, Xiaoxiang Rong, Raoying Xie, Li-Ting Jia, Huiyan Wang, Yujuan Qin, Lin Chen, Hong-Fen Shen, Xiaolin Lin, Jie Yang, Sheng Yang, Wei-Chao Hao, Yan Chen, Shengjun Xiao, Huirong Zhou, Taoyan Lin, Yushuang Chen, Yan Sun, Kai‐Tai Yao, Dong Xiao

Oncotarget

DOI

2015

A Fraction of CD133+ CNE2 Cells Is Made of Giant Cancer Cells with Morphological Evidence of Asymmetric Mitosis

Qingping Jiang, Qianbing Zhang, Shuang Wang, Siming Xie, Weiyi Fang, Zhen Liu, Jinsong Liu, Kai‐Tai Yao

Journal of Cancer

DOI

2014

甲基转移酶对鼻咽癌细胞中DLC-1基因表达的影响

冯湘玲，陈欢，刘卫东，张畅，祝斌，王磊，李敏，周文，姚开泰，任彩萍

《生命科学研究》

2014

鼻咽癌干细胞标志物的检测意义

江庆萍，谢思明，王爽，储兵，姚开泰

《实用癌症杂志》

2014

姚开泰院士集

姚开泰

《人民军医出版社》

2014

Effects of epigallocatechin gallate on the proliferation and apoptosis of the nasopharyngeal carcinoma cell line CNE2

Weijun Zhang, Ping Xun Yang, Fei Gao, Jie Wu Yang, Kai‐Tai Yao

Experimental and Therapeutic Medicine

DOI

2014

Depletion of intermediate filament protein Nestin, a target of microRNA-940, suppresses tumorigenesis by inducing spontaneous DNA damage accumulation in human nasopharyngeal carcinoma

Ji Ma, Fenyong Sun, Chengyunxiao Li, Yong Zhang, Wenrui Xiao, Zhenggang Li, Qiuhui Pan, H Zeng, G Xiao, Kai‐Tai Yao, An Hong, Jing An

Cell Death and Disease

DOI

2014

Aberrant CpG island methylation of PTEN is an early event in nasopharyngeal carcinoma and a potential diagnostic biomarker

JINBANG LI, Pinggui Gong, Xiaoming Lyu, Kai‐Tai Yao, Xin Li, Hong Peng

Oncology Reports

DOI

2014

Junctional adhesion molecule-A, an epithelial–mesenchymal transition inducer, correlates with metastasis and poor prognosis in human nasopharyngeal cancer

Yunhong Tian, Yunming Tian, Weijun Zhang, Wei Fang, Jing Yang, Xiaojun Luo, Tao You Zhou, Bing Hou, Qian Shen, Xu-Bing Deng, Yihan Qiu, Kai‐Tai Yao

Carcinogenesis

DOI

2013

鼻咽癌组织中梭形癌细胞具有上皮-间充质转化及肿瘤干细胞特性

罗伟仁，姚开泰

《临床与实验病理学杂志》

2013

间质标志物巢蛋白在鼻咽癌中的表达及其临床意义

罗伟仁，姚开泰

《临床与实验病理学杂志》

2013

CDK4 mRNA在鼻咽癌的表达及临床意义

陈衍，麦春平，姚开泰，刘真，方唯意

《广东药科大学学报》

2013

Cancer stem cell characteristics, ALDH1 expression in the invasive front of nasopharyngeal carcinoma

Weiren Luo, Kai‐Tai Yao

Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin

DOI

2013

Cancer stem‐like cell properties are regulated by EGFR / AKT /β–catenin signaling and preferentially inhibited by gefitinib in nasopharyngeal carcinoma

Lei Ma, Gong Zhang, Xiaobo Miao, Xubin Deng, Yue Wu, Ying Liu, Zhi‐Ru Jin, Xi‐Qing Li, Qiu‐Zhen Liu, Du‐Xin Sun, Joseph R. Testa, Kai‐Tai Yao, Guang‐Hui Xiao

FEBS Journal

DOI

2013

Promoter hypermethylation along with LOH, but not mutation, contributes to inactivation of DLC‐1 in nasopharyngeal carcinoma

Xiangling Feng, Caiping Ren, Wen Hu Zhou, Weidong Liu, Liang Zeng, Guifei Li, Lei Wang, Min Li, Bin Zhu, Kai‐Tai Yao, Xingjun Jiang

Molecular Carcinogenesis

DOI

2013

携带Fluc和ZsGreen双报告基因小鼠iPS细胞系的建立

樊全荣，史俊文，贾俊双，高飞，张余琴，赵尊兰，姚开泰，肖东

《中国癌症杂志》

2013

MTA1 contributes to actin cytoskeleton reorganization and metastasis of nasopharyngeal carcinoma by modulating Rho GTPases and Hedgehog signaling

Qingcui Song, Yiyi Li, Xiaokang Zheng, Yuan Fang, Yilan Chao, Kai‐Tai Yao, Xiaoxia Zhu

The International Journal of Biochemistry & Cell Biology

DOI

2013

EBV-miR-BART1 is involved in regulating metabolism-associated genes in nasopharyngeal carcinoma

Yanfen Ye, Ying Zhou, Lan Zhang, Yuxiang Chen, Xiaoming Lyu, Longmei Cai, Yaoyong Lu, Yizhen Deng, Jianguo Wang, Kai‐Tai Yao, Weiyi Fang, Hongbing Cai, Xin Li

Biochemical and Biophysical Research Communications

DOI

2013

Molecular Characterization and Clinical Implications of Spindle Cells in Nasopharyngeal Carcinoma: A Novel Molecule-Morphology Model of Tumor Progression Proposed

Weiren Luo, Kai‐Tai Yao

PLoS ONE

DOI

2013

Correction: Embryonic Stem Cells Markers SOX2, OCT4 and Nanog Expression and Their Correlations with Epithelial-Mesenchymal Transition in Nasopharyngeal Carcinoma

Weiren Luo, Siyi Li, Bailu Peng, Yanfen Ye, Xubin Deng, Kai‐Tai Yao

PLoS ONE

DOI

2013

Radioactive 125I Seed Inhibits the Cell Growth, Migration, and Invasion of Nasopharyngeal Carcinoma by Triggering DNA Damage and Inactivating VEGF-A/ERK Signaling

Yunhong Tian, Qiang Xie, Yunming Tian, Ying Liu, Zuoping Huang, Cundong Fan, Bing Hou, Dan Sun, Kai‐Tai Yao, Tianfeng Chen

PLoS ONE

DOI

2013

Erratum: Loss of connective tissue growth factor as an unfavorable prognosis factor activates miR-18b by PI3K/AKT/C-Jun and C-Myc and promotes cell growth in nasopharyngeal carcinoma

Xueying Yu, Y Zhen, Haijuan Yang, Hui Wang, Yang Zhou, E Wang, Franco M Marincola, C Mai, Yixia Chen, H Wei, Y Song, Xiaoming Lyu, Yuman Ye, Lianxu Cai, Qiangyun Wu, Ming Fei Zhao, Shengni Hua, Q Fu, Yanling Zhang, Kai‐Tai Yao, Z Liu, Xiaodan Li, Weiyang Fang

Cell Death and Disease

DOI

2013

Over-expression of BCAT1, a c-Myc target gene, induces cell proliferation, migration and invasion in nasopharyngeal carcinoma

Wen Hu Zhou, Xiangling Feng, Caiping Ren, Xingjun Jiang, Weidong Liu, Wei Huang, Zhihong Liu, Zan Li, Liang Zeng, Lei Wang, Bin Zhu, Jia Shi, Jie Liu, Chang Zhang, Yanyu Liu, Kai‐Tai Yao

Molecular Cancer

DOI

2013

Loss of connective tissue growth factor as an unfavorable prognosis factor activates miR-18b by PI3K/AKT/C-Jun and C-Myc and promotes cell growth in nasopharyngeal carcinoma

Xinyi Yu, Y Zhen, Huiling Yang, Hui Wang, Ying Chun Zhou, E Wang, Francesco Maria Marincola, C Mai, Yixia Chen, H Wei, Ye Song, Xiaoming Lyu, Yuman Ye, Lianxu Cai, Qiangyun Wu, Ming Fei Zhao, Shengni Hua, Qiang Fu, Yanling Zhang, Kai‐Tai Yao, Z Liu, Xiaodan Li, Weiyi Fang

Cell Death and Disease

DOI

2013

Embryonic Stem Cells Markers SOX2, OCT4 and Nanog Expression and Their Correlations with Epithelial-Mesenchymal Transition in Nasopharyngeal Carcinoma

Weiren Luo, Siyi Li, Bailu Peng, Yanfen Ye, Xubin Deng, Kai‐Tai Yao

PLoS ONE

DOI

2013

miR-9 modulates the expression of interferon-regulated genes and MHC class I molecules in human nasopharyngeal carcinoma cells

Fei Gao, Zunlan Zhao, Wentao Zhao, Quan-Rong Fan, Shengchun Wang, Jing Li, Yuqing Zhang, Junwen Shi, Xiaolin Lin, Sheng Yang, Raoying Xie, Wei Liu, Tingting Zhang, Yongliang Sun, Kang Xu, Kai‐Tai Yao, Dong Xiao

Biochemical and Biophysical Research Communications

DOI

2013

Neoplastic spindle cells in nasopharyngeal carcinoma possess properties of epithelial-mesenchymal transition and cancer stem cells

Weiren Luo, Kai‐Tai Yao

Experimental Pathology

2013

Expression of a mesenchymal marker N-cadherin in nasopharyngeal carcinoma and its clinical significance

Kai‐Tai Yao

Experimental Pathology

2012

以肿瘤干细胞为靶的免疫治疗

郭坤元，姚开泰

《中国肿瘤生物治疗杂志》

2012

携人PTHLH基因慢病毒表达载体的构建

樊英，李佳，陈靖，黄仲曦，姚开泰

《热带医学杂志》

2012

MYC Regulation of CHK1 and CHK2 Promotes Radioresistance in a Stem Cell-like Population of Nasopharyngeal Carcinoma Cells

Wenjun Wang, Si-Pei Wu, Jiabin Liu, Yongsheng Shi, Xue Ping Huang, Qian-Bing Zhang, Kai‐Tai Yao

Cancer Research

DOI

2012

Further evidence for the existence of major susceptibility of nasopharyngeal carcinoma in the region near HLA-A locus in Southern Chinese

Manli Zhao, Hongbing Cai, Xin Li, Hang Zheng, Xuexi Yang, Weiyi Fang, Longcheng Zhang, Ganguan Wei, Ming Li, Kai‐Tai Yao, Xin Li

Journal of Translational Medicine

DOI

2012

红色荧光蛋白和荧光素酶双报告基因转基因小鼠的建立

张余琴，林晓琳，贾俊双，谢饶英，樊全荣，赵尊兰，杨升，高飞，姚开泰，肖东

《中国癌症杂志》

2012

慢病毒载体法制备荧光素酶转基因小鼠

张余琴，林晓琳，贾俊双，高飞，李静，王胜纯，姚开泰，肖东

《热带医学杂志》

2012

携带Oct4、Klf4、Sox2、c-myc和EGFP基因小鼠肿瘤细胞株的建立

贾琦珺，史俊文，申洪芬，贾俊双，肖东，姚开泰

《热带医学杂志》

2012

Aldehyde dehydrogenase 1, a functional marker for identifying cancer stem cells in human nasopharyngeal carcinoma

Aibing Wu, Weiren Luo, Qianbing Zhang, Zhixiong Yang, Gong Zhang, Siyi Li, Kai‐Tai Yao

Cancer Letters

DOI

2012

Tumour budding and the expression of cancer stem cell marker aldehyde dehydrogenase 1 in nasopharyngeal carcinoma

Weiren Luo, Fei Gao, Siyi Li, Kai‐Tai Yao

Histopathology

DOI

2012

Overexpressed DNA-binding protein inhibitor 2 as an unfavorable prognosis factor promotes cell proliferation in nasopharyngeal carcinoma

Zhen Liu, Jing Chen, Weiren Luo, Huiling Yang, Aibing Wu, Yan Zhen, Xiaoli Yu, Hao Wang, Kai‐Tai Yao, Xin Li, Weiyi Fang

Acta Biochimica et Biophysica Sinica

DOI

2012

Neoplastic spindle cells in nasopharyngeal carcinoma show features of epithelial–mesenchymal transition

Weiren Luo, Xiaoyi Chen, Siyi Li, Aibing Wu, Kai‐Tai Yao

Histopathology

DOI

2012

High Expression of Nuclear Snail, but not Cytoplasmic Staining, Predicts Poor Survival in Nasopharyngeal Carcinoma

Weiren Luo, Siyi Li, Longmei Cai, Kai‐Tai Yao

Annals of Surgical Oncology

DOI

2012

Nuclear expression of N‐cadherin correlates with poor prognosis of nasopharyngeal carcinoma

Weiren Luo, Aibing Wu, Weiyi Fang, Siyi Li, Kai‐Tai Yao

Histopathology

DOI

2012

Aberrant expression of nuclear vimentin and related epithelial–mesenchymal transition markers in nasopharyngeal carcinoma

Weiren Luo, Weiyi Fang, Siyi Li, Kai‐Tai Yao

International Journal of Cancer

DOI

2011

鼻咽癌细胞株5-8F-EGFP和肝转移亚群5-8F-H3B-EGFP的基因表达谱分析

韩春，杨俊兰，姚开泰

《南方医科大学学报》

2011

Q-RT-PCR检测LAMC2、KLK6、SNCG在鼻咽癌肝转移细胞中的表达

韩春，谢卫兵，方唯意，刘腾飞，姚开泰

《西南国防医药》

2011

慢病毒载体介导的RNAi技术构建稳定抑制β-catenin的人鼻咽癌细胞株

姜睿，张弓，马磊，李锡清，姚开泰

《热带医学杂志》

2011

加强推进力度,促进转化医学发展

蔡红兵，李欣，孙学刚，方唯意，张龙城，杨明会，姚开泰

《南方医科大学学报》

2011

人诱导性多潜能干细胞(iPS细胞)系的建立

姚志芳，史俊文，贾俊双，申红芬，林晓琳，肖高芳，张晟，肖东，姚开泰

《生命科学研究》

2011

携带人c-Myc和EGFP基因慢病毒表达载体的构建

李艳青，史俊文，肖高芳，肖东，姚开泰

《热带医学杂志》

2011

Potential Tumor Suppressor NESG1 as an Unfavorable Prognosis Factor in Nasopharyngeal Carcinoma

Zhen Liu, Weiren Luo, Ying Chun Zhou, Yan Zhen, Huiling Yang, Xiaoli Yu, Yanfen Ye, Xin Li, Hao Wang, Qinping Jiang, Yajie Zhang, Kai‐Tai Yao, Weiyi Fang

PLoS ONE

DOI

2011

Construction of a stable human nasopharyngeal carcinoma cell line with down-regulated expression of β-catenin

Kai‐Tai Yao

Journal of Tropical Medicine

2011

Underlying mechanisms for LTF inactivation and its functional analysis in nasopharyngeal carcinoma cell lines

Hejun Zhang, Xiangling Feng, Weidong Liu, Xingjun Jiang, Wenjiao Shan, Chengan Huang, Hongmei Yi, Bin Zhu, Wen Hu Zhou, Lei Wang, Chunmei Liu, Lihua Zhang, Wenting Jia, Wei Huang, Guifei Li, Jia Shi, Siyi Wanggou, Kai‐Tai Yao, Caiping Ren

Journal of Cellular Biochemistry

DOI

2011

MiR-26a Inhibits Cell Growth and Tumorigenesis of Nasopharyngeal Carcinoma through Repression of EZH2

Juan Lü, Ming‐Liang He, Lu Wang, Ying Chen, Xiong Liu, Qi Dong, Yangchao Chen, Ying Peng, Kai‐Tai Yao, Hsiang‐Fu Kung, Xiangping Li

Cancer Research

DOI

2010

转录因子Snail及黏附分子E-cadherin在鼻咽癌中的表达

王爽，吕丽春，周伟，姚开泰

《广东医学》

2010

鼻咽癌EMT相关基因的筛选及生物信息学分析

陈靖，樊英，李佳，黄仲曦，姚开泰

《热带医学杂志》

2010

鼻咽癌细胞株侧群细胞染色条件的优化及其表面标记物的测定

焦锋，邱际华，张千兵，姚开泰，刘求真

《陆军军医大学学报》

2010

佛波醇脂和溴脱氧尿嘧啶核苷促进鼻咽癌细胞中CD133的表达

江庆萍，方唯意，姚开泰

《肿瘤》

2010

鼻咽癌细胞系候选癌基因的筛选

樊英，李佳，黄仲曦，姚开泰

《实用医学杂志》

2010

原位鼻咽癌裸鼠模型血清蛋白质组学的研究

吴丽莎，蒋星军，刘卫东，周文，冯湘玲，李雪华，祝斌，王磊，刘春梅，姚开泰，任彩萍

《生命科学研究》

2010

鼻咽癌细胞株中标记滞留细胞(LRGs)的建立与检测(英文)

江庆萍，姚开泰

《癌症》

2010

慢病毒载体法制备红色荧光蛋白转基因小鼠

贾俊双，肖高芳，林晓琳，张晟，姚志芳，杜文婷，申红芬，刘科，饶子亮，孙妍，姚开泰，肖东

《中国比较医学杂志》

2010

Screening of nasopharyngeal carcinoma EMT-related genes and their bioinformatics analysis.

Jing Chen, Ying Fan, Jia Li, Zhongxi Huang, Kai‐Tai Yao

Journal of Tropical Medicine

2010

Isolation and detection of label-retaining cells in a nasopharyngeal carcinoma cell line

Qingping Jiang, Kai‐Tai Yao

《癌症：英文版》

DOI

2010

Decreased expression of updated NESG1 in nasopharyngeal carcinoma: Its potential role and preliminarily functional mechanism

Zhen Liu, Xin Li, Xiufang He, Qingping Jiang, Siming Xie, Xiaoli Yu, Yan Zhen, Guang‐Hui Xiao, Kai‐Tai Yao, Weiyi Fang

International Journal of Cancer

DOI

2010

Increased expression of MMP9 is correlated with poor prognosis of nasopharyngeal carcinoma

Zhen Liu, Lixia Li, Zhixiong Yang, Weiren Luo, Xin Li, Huiling Yang, Kai‐Tai Yao, Bin Wu, Weiyi Fang

BMC Cancer

DOI

2010

Over-expression of eukaryotic translation initiation factor 4 gamma 1 correlates with tumor progression and poor prognosis in nasopharyngeal carcinoma

Luxia Tu, Zhen Liu, Xiufang He, Ying He, Huiling Yang, Qingping Jiang, Siming Xie, Guang‐Hui Xiao, Xin Li, Kai‐Tai Yao, Weiyi Fang

Molecular Cancer

DOI

2010

TPA and BrdU promote CD133 expression in nasopharyngeal carcinoma cells

Kai‐Tai Yao

Tumori

2010

Gene expression profile changes and possible molecular subtypes in differentiated‐type nonkeratinizing nasopharyngeal carcinoma

Shuang Wang, Xin Li, Zuguo Li, Juan Lü, Weiyi Fang, Yanqing Ding, Kai‐Tai Yao

International Journal of Cancer

DOI

2009

CXCR4/SDF-1对鼻咽癌细胞增殖与迁移能力的影响

邱际华，刘求真，陈丽，焦锋，姚开泰

《陆军军医大学学报》

2009

人Snail基因RNAi慢病毒载体对鼻咽癌5-8F细胞增殖和侵袭的影响

陈丽，刘求真，邱际华，焦锋，姚开泰

《陆军军医大学学报》

2009

可视化人鼻咽癌细胞模型6-10B-EGFP的建立

刘腾飞，谢卫兵，刘莉，姚开泰

《中南医学科学杂志》

2009

可视化人鼻咽癌细胞模型5-8F-EGFP的建立

刘腾飞，谢卫兵，刘莉，姚开泰

《肿瘤预防与治疗》

2009

谷胱甘肽硫转移酶M1基因编码区多态性与中国南方人群鼻咽癌易感性的关系(英文)

何英，周钢桥，李欣，董晓佳，柴先奇，姚开泰

《癌症》

2009

10种ABC转运蛋白在鼻咽癌顺铂耐药细胞系中的表达

谢思明，杜莎莎，方唯意，姚开泰

《生物化学与生物物理进展》

2009

PTHLH在鼻咽癌细胞系及组织中表达上调

赵瑾，黄仲曦，刘允，姚开泰

《热带医学杂志》

2009

Tet-on系统调控A20基因在鼻咽癌肝转移亚系中的表达

刘芳，谢卫兵，周来勇，姚开泰

《热带医学杂志》

2009

可视化鼻咽癌细胞模型CNE2-EGFP的建立

刘腾飞，谢卫兵，刘莉，姚开泰

《热带医学杂志》

2009

鼻咽癌组织中ABCC2的表达与顺铂化疗敏感性的关系

谢思明，江庆萍，方唯意，储兵，姚开泰

《广东医学》

2009

GSTM1基因编码区SNP位点T1270533G与鼻咽癌的相关性

何英，周钢桥，李欣，董晓佳，姚开泰

《南方医科大学学报》

2009

鼻咽癌凋亡及增生相关基因筛选与分析

周毅波，黄仲曦，任彩萍，祝斌，姚开泰

《南方医科大学学报》

2009

慢病毒介导的siRNA靶向干扰EIF4G1鼻咽癌稳定细胞株的建立

涂露霞，方唯意，刘真，李欣，何英，谢思明，姚开泰

《南方医科大学学报》

2009

EBV全基因组芯片的制备及应用

方唯意，郑文岭，马文丽，刘真，李欣，姚开泰

《南方医科大学学报》

2009

慢病毒携带shRNA抑制CR-1基因表达对CNE-2细胞特性的影响

吴正蓉，吴立蓉，姚开泰

《中山大学学报(医学科学版)》

2009

组织特异性表达基因PLUNC调控元件的生物信息学分析

王爽，姚开泰

《热带医学杂志》

2009

Effect of CXCR4/SDF-1 on proliferation and migration of human nasopharyngeal carcinoma cell lines

Kai‐Tai Yao

Di-san junyi daxue xuebao

2009

诱导性多潜能干细胞(iPS cells)——现状及前景展望

申红芬，姚志芳，肖高芳，贾俊双，肖东，姚开泰

《生物化学与生物物理进展》

2009

诱导多能干细胞研究进展

李贵妃，任彩萍，姚开泰

《生命科学》

2009

携带人miR302和EGFP基因慢病毒表达载体构建

申红芬，贾俊双，肖高芳，姚志芳，肖东，姚开泰

《热带医学杂志》

2009

Microarray analysis of differentially expressed genes between nasopharyngeal carcinoma cell lines 5-8F and 6-10B

Jia Li, Ying Fan, Jing Chen, Kai‐Tai Yao, Zhongxi Huang

Cancer Genetics and Cytogenetics

DOI

2009

Cripto-1 overexpression is involved in the tumorigenesis of nasopharyngeal carcinoma

Zhengrong Wu, Gang Li, Lirong Wu, Desheng Weng, Xiangping Li, Kai‐Tai Yao

BMC Cancer

DOI

2009

Lentiviral vector for RNA interference of human Snail gene inhibits proliferation and invasion of nasopharyngeal carcinoma 5-8F cell line

Kai‐Tai Yao

Di-san junyi daxue xuebao

2009

Establishment of A CNE2-EGFP nasopharyngeal carcinoma cell line.

Tengfei Liu, Xie Wei-bing, Liu Li, Kai‐Tai Yao

Journal of Tropical Medicine

2008

鼻咽癌中上皮间充质改变现象观察

江庆萍，王爽，邹桂华，方唯意，姚开泰

《热带医学杂志》

2008

TGFBR2表达下调可能是鼻咽癌的恶性生物标志

方唯意，江庆萍，刘真，李欣，刘求真，王爽，谢思明，鲁娟，刘腾飞，谢卫兵，涂露霞，黄静，姚开泰

《中国现代医学杂志》

2008

趋化因子受体CXCR4在鼻咽癌中的表达及意义

王爽，鲁娟，吕丽春，姚开泰

《肿瘤防治研究》

2008

实时荧光定量RT-PCR检测鼻咽癌骨转移相关基因表达的研究

翟晓晓，刘腾飞，姚开泰

《广东药科大学学报》

2008

鼻咽癌中ABC转运蛋白基因表达的研究

杜莎莎，姚开泰

《南方医科大学学报》

2008

鼻咽癌淋巴结转移动物模型的建立及其转移相关标签基因的筛选

冷雷，刘腾飞，黄仲曦，谢卫兵，姚开泰

《南方医科大学学报》

2008

肿瘤干细胞与肿瘤转移

刘求真，姚开泰

《肿瘤学杂志》

2008

应用酵母双杂交系统筛选与NAP1相互作用的蛋白质

王烨，李峰，刘求真，谢卫兵，姚开泰

《湖南文理学院学报(自然科学版)》

2008

Reduced expression of TGFBR2 and its significance in NPC pathogenesis

Kai‐Tai Yao

Zhongguo xiandai yixue/Zhongguo xiandai yixue zazhi

2008

Expression of Chemokine Receptor CXCR4 in Nasopharyngeal Carcinomas and Its Clinical Significance

Kai‐Tai Yao

Zhongliu fangzhi yanjiu

2008

Expressions of bone metastasis genes in nasopharyngeal carcinoma by real-time fluorescent quantitative RT-PCR

Kai‐Tai Yao

2008

人胚胎干细胞和拟胚体基因表达谱的初步分析

赵明，任彩萍，杨红，蒋星军，曾英，王磊，周文，祝斌，冯湘玲，姚开泰

《生命科学研究》

2008

早期胚胎各器官CXCR4和CD44表达的观察

江庆萍，方唯意，王开昕，王爽，姚开泰

《中国组织化学与细胞化学杂志》

2008

慢病毒介导的外源基因体外投递系统的建立

贾俊双，孙妍，肖东，姚开泰

《热带医学杂志》

2008

微小RNA miR-26a的克隆及其慢病毒表达载体的构建

鲁娟，王爽，揭荣荣，姚开泰

《热带医学杂志》

2008

Screening potentially drug resistant and multidrug resistant genes in NPC cells with metastatic ability

Weiyi Fang, Zhen Liu, Siming Xie, Qingping Jiang, Shuang Wang, Xin Li, Kai‐Tai Yao

《肿瘤研究与临床》

DOI

2008

The DLC-1 −29A/T Polymorphism Is Not Associated with Nasopharyngeal Carcinoma Risk in Chinese Population

Xiangling Feng, Wen Hu Zhou, Hong Li, Weiyi Fang, Yi-Bo Zhou, Kai‐Tai Yao, Caiping Ren

Genetic Testing

DOI

2007

NK细胞免疫编辑后的人鼻咽癌细胞株CNE2 HLA I类分子和MICA/MICB的表达及其对NK细胞杀伤活性的影响

郭坤元，梅家转，姚开泰，尹晓林

《空军军医大学学报》

2007

利用RNA干扰技术研究PTX1在鼻咽癌中的功能

周文，李虹，冯湘玲，王磊，祝斌，李辉，姚开泰，任彩萍

《中南大学学报(医学版)》

2007

EBV全基因组基因芯片构建与初步验证

方唯意，刘真，李欣，刘求真，刘腾飞，姚开泰

《湖南师范大学学报(医学版)》

2007

血管形成抑制剂Tumstatin在鼻咽癌中表达鉴定及基因克隆

方唯意，刘真，杨慧龄，周宏珍，刘腾飞，王爽，李欣，刘求真，江庆萍，谢思明，姚开泰

《湖南师范大学学报(医学版)》

2007

PLUNC基因编码区单核苷酸多态位点G14595T与鼻咽癌的相关研究

何英，丁彦青，黄仲曦，姚开泰

《中华医学杂志》

2007

鼻咽癌组织中EB病毒潜伏相关基因的表达

尹志华，蒋卫红，李峰，杨旭宇，冯湘玲，姚开泰

《中国病理生理杂志》

2007

Plunc基因AF172993序列不是complete CDS

方唯意，刘真，李欣，王爽，刘求真，刘腾飞，乔贵林，姚开泰

《南方医科大学学报》

2007

人鼻咽癌细胞株CNE2对NK细胞KIR/NKG2D受体的免疫编辑作用及其对NK细胞杀伤功能的影响

郭坤元，梅家转，姚开泰

《南方医科大学学报》

2007

人鼻咽癌组织中转录因子相关基因的差异表达分析

王爽，吕丽春，方唯意，姚开泰

《南方医科大学学报》

2007

鼻咽癌组织中GNAT1基因的表达、杂合性丢失及甲基化分析

易红梅，任彩萍，彭丹，周亮，李辉，姚开泰

《癌症》

2007

血管形成抑制剂Canstatin在鼻咽癌中表达鉴定及基因克隆

方唯意，刘真，杨慧玲，周宏珍，王爽，刘腾飞，李欣，刘求真，江庆萍，谢思明，姚开泰

《中南医学科学杂志》

2007

Construction and Preliminary Verification for EBV Genome-wide Genechip

Kai‐Tai Yao

Journal of Hunan Normal University

2007

人胚胎干细胞的体外定向分化

刘卫东，任彩萍，姚开泰

《生命科学》

2007

呼吸道上皮中的短暂扩充细胞——clara细胞

周文，姚开泰

《生命科学》

2007

Functional Evidence for a Nasopharyngeal Carcinoma-Related Gene BCAT1 Located at 12p12

Wen Hu Zhou, Xiangling Feng, Hong Li, Lei Wang, Hui Li, Bin Zhu, Hejun Zhang, Kai‐Tai Yao, Caiping Ren

Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics

DOI

2006

免疫磁珠法分离鼻咽癌基质的T淋巴细胞

李虹，韩为农，冯湘玲，周文，张贺军，丁彦青，姚开泰

《生命科学研究》

2006

鼻咽癌细胞肝转移亚株的建立

韩春，王爽，刘莉，姚开泰

《南方医科大学学报》

2006

SEMA3B基因在鼻咽癌组织中的表达、杂合性丢失和甲基化分析

易红梅，任彩萍，彭丹，杨旭宇，赵明，姚开泰

《生命科学研究》

2006

DNAJC10基因在鼻咽癌中的表达及表达下调机制的研究

周亮，任彩萍，单文姣，姚开泰

《生命科学研究》

2006

肿瘤干细胞研究进展

杨旭宇，姚开泰

《国际肿瘤学杂志》

2006

NAP1基因在鼻咽癌组织中表达下调原因的初步分析

李峰，杨旭宇，尹志华，姚开泰

《中国病理生理杂志》

2006

干细胞壁龛功能的研究进展

张贺军，李虹，姚开泰

《生命科学》

2006

应用小鼠整体原位杂交技术检测MDM2在鼠胚发育不同阶段的表达

周文，冯湘玲，李虹，王磊，任彩萍，姚开泰

《生命科学研究》

2006

Chromosomal imbalances in nasopharyngeal carcinoma: a meta-analysis of comparative genomic hybridization results

Xin Li, Ena Wang, Yingdong Zhao, Jiaqiang Ren, Ping Jin, Kai‐Tai Yao, Francesco Maria Marincola

Journal of Translational Medicine

DOI

2005

3号染色体短臂21-22区域63个新基因在鼻咽癌组织中的差异表达

彭宏，赵彤，姚开泰

《南方医科大学学报》

2005

EBV病毒全基因组cDNA探针的设计与制备(英文)

方唯意，郑文岭，马文丽，刘腾飞，王爽，谢卫兵，李虹，任彩萍，姚开泰

《南方医科大学学报》

2005

运用蛋白质组学技术研究EB病毒诱导鼻咽癌细胞CNE2表达变化的蛋白质

江培洲，甘明，黄华，沈新明，应万涛，钱小红，姚开泰

《中山大学学报(医学科学版)》

2005

利用报道基因检测鼻咽癌细胞的RNA干扰作用

尹志华，任彩萍，李峰，蒋卫红，杨旭宇，冯湘玲，姚开泰

《癌症》

2005

组织芯片技术检测人鼻咽癌组织及细胞株KIAA1173基因的表达

张三泉，彭宏，宋兰英，李先茂，蒋会勇，姚开泰，赵彤

《癌症》

2005

表达人KIAA1173基因的鼻咽癌6-10B细胞模型的建立

张三泉，蒋会勇，韩西群，胡海，张进华，姚开泰，赵彤

《广东医学》

2005

人KIAA1173基因的克隆、转染及生物学特性的实验研究

张三泉，彭宏，将会勇，胡海，张进华，姚开泰，赵彤

《南方医科大学学报》

2005

pEGX-4T-2/NAP1融合蛋白的原核表达及鉴定

李峰，田宗城，赵东海，张建平，尹志华，姚开泰

《湖南文理学院学报(自然科学版)》

2005

改进的核移植方法完成小鼠卵丘细胞重组胚的早期发育

沈新明，乔贵林，江培洲，李欣，黄华，姚开泰

《南方医科大学学报》

2005

氨基酸浓度对昆明小鼠胚胎体外发育的影响(英文)

邓星，王爽，黄吴键，刘求真，谢卫兵，张庆凌，方唯意，刘腾飞，韩春，杜莎莎，吴丽莎，丁彦青，姚开泰

《南方医科大学学报》

2005

不同电融合条件对小鼠卵丘细胞核移植重组胚融合和早期发育的影响

江培洲，沈新明，乔贵林，黄华，姚开泰

《南方医科大学学报》

2005

从基因组和肿瘤研究的进展瞻望中西医结合

姚开泰，任彩萍

《科学中国人》

2005

Proteome Analysis of Antiproliferative Mechanism of 12-O-Tetradecanoylphorbol 13-Acetate on Cultured Nasopharyngeal Carcinoma CNE2 Cells

Peizhou Jiang, Ming Gan, Hua Huang, Xinming Shen, Shuang Wang, Kai‐Tai Yao

Journal of Proteome Research

DOI

2004

人鼻咽癌不同部位组织相关基因表达谱的研究

韩慧霞，姚连生，王爽，韩为农，姚开泰

《南方医科大学学报》

2004

转染人pIgR的小鼠鼻咽上皮细胞在EBV感染前后基因表达谱差异

王爽，吕丽春，李虹，江培洲，姚开泰

《南方医科大学学报》

2004

用文献轮廓挖掘鼻咽癌微阵列表达数据

黄仲曦，姚开泰

《南方医科大学学报》

2004

鼻咽癌和结直肠癌多基因多阶段多途径模型的探讨

尹志华，黄仲曦，刘腾飞，李虹，姚开泰

《中华肿瘤杂志》

2004

鼻咽癌相关基因NAP1的克隆及鉴定

李峰，蒋卫红，杨旭宇，尹志华，冯湘玲，刘卫东，王磊，周文，姚开泰

《生物化学与生物物理进展》

2004

鼻咽癌患者的Smad2/4基因突变分析

姚俊岩，安靚，谢敏德，蔡林儿，孔怡琳，姚开泰，杨晓

《生物技术通讯》

2004

细胞间接触是EB病毒自发感染人类上皮细胞的有效途径

江培洲，沈新明，吕丽春，黄华，姚开泰

Virologica Sinica

2004

运用双向聚丙烯酰胺凝胶电泳和图像软件分析TPA处理NIH3T3细胞前后的蛋白质表达谱差异

沈新明，江培洲，黄华，李欣，姚开泰

《南方医科大学学报》

2004

一种简便高效的人胚胎干细胞转染方法

赵明，尹志华，蒋星军，杨旭宇，姚开泰，任彩萍

《中国生物工程杂志》

DOI

2004

双向凝胶电泳-飞行时间质谱法分析促癌剂TPA诱导NIH3T3细胞表达变化的蛋白质

江培洲，甘明，沈新明，黄华，李欣，姚开泰

《中山大学学报(医学科学版)》

2004

鼠γ疱疹病毒68(MHV68):研究γ疱疹病毒感染的模型

尹志华，姚开泰

《病毒学报》

2004

Construction of tree models for pathogenesis of nasopharyngeal carcinoma

Zhongxi Huang, Richard Desper, Alejandro A. Schäffer, Zhihua Yin, Xin Li, Kai‐Tai Yao

Genes Chromosomes and Cancer

DOI

2003

EB病毒亲上皮性基因BARF1研究进展

尹志华，姚开泰

《医学分子生物学杂志》

2003

鼻咽癌组织RASSF1A基因的表达

彭宏，赵彤，姚开泰

《南方医科大学学报》

2003

一种特异的EBER-1原位杂交探针检测石蜡组织中的EB病毒

齐宗利，赵彤，周新华，刘换新，黄宏宇，韩西群，姚开泰

《中华实验和临床病毒学杂志》

2003

用芯片技术分析鼻咽癌周围的基质细胞基因表达特点

李虹，韩为农，冯湘玲，周文，姚开泰

《癌症》

2003

用鼻咽相对特异性调控区建立N-LMP1转基因小鼠

张玲，蓝轲，冯湘玲，乔贵林，沈新民，石益民，李虹，姚开泰

Acta Biochimica et Biophysica Sinica

2003

人多聚免疫球蛋白受体转基因鼠的建立

吕丽春，何英，蓝轲，沈新明，黄华，江培洲，王爽，徐守军，姚开泰

《南方医科大学学报》

2003

EB病毒诱发人B细胞淋巴瘤的分子病理特性

甘润良，尹志华，刘腾飞，冬毕华，周建国，姚开泰

Acta Biochimica et Biophysica Sinica

2003

高通量SNP基因分型技术研究进展

方唯意，姚开泰

《医学分子生物学杂志》

2003

严重急性呼吸综合征病原体检测及临床病理学观察

丁彦青，王慧君，申洪，李祖国，耿舰，韩慧霞，蔡俊杰，李欣，康伟，翁德胜，陆药丹，姚开泰

《中华病理学杂志》

2003

非洲爪蟾GATA-1b中与GATA-1a的差异位点突变后的功能

冯湘玲，刘卫东，李虹，王磊，杨旭宇，韩为农，周文，姚开泰

Acta Biochimica et Biophysica Sinica

2002

鼻咽癌来源LMP1转基因小鼠的制备

蓝轲，乔贵林，沈新民，张玲，吕丽春，姚开泰

《动物医学进展》

2002

鼻咽癌来源潜伏膜蛋白1的表达诱发转基因小鼠鼻咽不典型增生

蓝轲，乔贵林，沈新民，张玲，吕丽春，姚开泰

《动物医学进展》

2002

鼻咽癌DLC1基因的表达研究

彭宏，赵彤，姚开泰

《中华耳鼻咽喉头颈外科杂志》

2002

用非洲爪蟾分析新调控子PLUNC-p组织调控特性

张玲，冯湘玲，周文，李虹，史建凌，姚开泰

《中国病理生理杂志》

2002

鼻咽癌中TSG101基因的突变研究

杨旭宇，王磊，冯湘玲，周文，尹志华，姚开泰

《生命科学研究》

2002

人鼻咽与鼻咽癌cDNA阵谱中DNA修复相关基因表达差异的初步研究

韩为农，李虹，谢鹭，许亮国，张玲，姚开泰

《中华肿瘤杂志》

2002

变性高效液相色谱法筛选鼻咽癌相关基因单核苷酸多态性

黄华，江培洲，沈新明，姚开泰，周宇凤

《南方医科大学学报》

2002

EB病毒在SCID小鼠体内诱发人B淋巴细胞肿瘤

甘润良，蓝柯，尹志华，王丽江，许亮国，姚开泰

《中国肿瘤临床》

2002

高浓度EB病毒感染人永生化上皮细胞Hacat系

江培洲，沈新明，黄华，姚开泰

《南方医科大学学报》

2002

用曲细精管微注射法建立绿色荧光蛋白转基因小鼠

沈新明，乔贵林，张玲，江培洲，黄华，姚开泰

《南方医科大学学报》

2002

显微操作仪快速分离癌细胞并提取微量RNA的方法

江培洲，沈新明，黄华，石益民，姚开泰

《南方医科大学学报》

2002

胞内精子注射法制备转基因爪蟾的研究

江培洲，冯湘玲，黄华，沈新明，史剑凌，姚开泰

《南方医科大学学报》

2002

显微切割结合RNA线性扩增技术的应用

韩为农，李虹，王爽，周文，姚开泰

《癌症》

2002

DIG标记DNA探针检测noggin在爪蟾胚胎中的表达

周文，冯湘玲，杨旭宇，王磊，姚开泰

《生命科学研究》

2002

试析影响国家自然科学基金中标率的两大因素

杨玉文，胡隆菊，刘卫东，姚开泰

《中华医学科研管理杂志》

2002

POSSIBLE REASONS FOR TP53 ACCUMULATION IN NASO-PHARYNGEAL CARCINOMA USING ATLAS HUMAN CANCER cDNA EXPRESSION ARRAY

李虹，韩为农，张玲，冯湘玲，姚开泰

Chinese Journal of Cancer Research

2001

两种不同来源LMP1致瘤性的比较研究

蓝轲，任彩萍，谢鹭，何志巍，甘润良，姚开泰

《癌症》

2001

用cDNA Array探讨鼻咽癌组织TP53积聚的可能原因

李虹，韩为农，张玲，谢鹭，姚开泰

《癌症》

2001

人鼻咽与鼻咽癌组织p53调节基因差异表达的研究

李虹，韩为农，张玲，谢鹭410078长沙，姚开泰

《中华肿瘤杂志》

2001

稳定表达鼻咽癌来源潜伏膜蛋白1基因的鼻咽癌细胞系的建立

蓝轲，甘润良，任彩萍，何志巍，谢鹭，姚开泰

《中国病理生理杂志》

2001

EB病毒及其相关动物模型

任彩萍，姚开泰

《临床与病理杂志》

2001

用染色体缓移法分析5’端未知序列

张玲，何志巍，李虹，韩为农，姚开泰

《癌症》

2001

EBV感染及TPA处理前后人CR2转染细胞的基因差异表达谱

任彩萍，刘卫东，何志巍，蓝轲，王慧，姚开泰

Acta Biochimica et Biophysica Sinica

2001

采用原位杂交及电镜检测CR2转染小鼠细胞的EB病毒感染

任彩萍，蓝轲，冯湘玲，许亮国，何志巍，刘卫东，王慧，姚开泰

《病毒学报》

2001

TP53结构功能及活性调节的最新研究进展

李虹，姚开泰

《医学分子生物学杂志》

2001

一种快速检测启动子特异性的方法

冯湘玲，蓝轲，张玲，周文，史剑凌，刘卫东，姚开泰

《生命科学研究》

2000

p51基因在鼻咽癌组织中表达的研究

李虹，张玲，姚开泰

《中国病理生理杂志》

2000

鼻咽癌组织基因表达谱的研究

许亮国，谢鹭，王磊，何志巍，杨玉文，姚开泰

《中国病理生理杂志》

2000

用原位PCR方法检测鼻咽癌组织中的EB病毒

许亮国，杨旭宇，谢鹭，陈曲侯，王珣章，姚开泰

《中华肿瘤杂志》

2000

用cDNA表达阵谱分析小鼠鼻咽部相对特异表达基因

张玲，凌建华，何志巍，姚开泰

《生物化学与生物物理进展》

2000

鼻咽癌组织中EB病毒的不同原位检测方法比较

许亮国，姚开泰，谢鹭，周文，杨玉文，陈曲侯，王珣章

《癌症》

2000

鼻咽癌中生长因子细胞因子mRNA差异表达分析

谢鹭，许亮国，蓝轲，何志巍，李官成，姚开泰

《中国免疫学杂志》

2000

用肿瘤cDNA阵列分析鼻咽癌组织的基因表达

谢鹭，许亮国，何志巍，周文，王磊，张玲，李赞，姚开泰

《自然科学进展》

2000

肿瘤转移的分子机制及其调控因素研究进展

孙青，江培洲，沈新明，姚开泰

《国际肿瘤学杂志》

2000

cDNA阵列和微阵列在鼻咽癌发生机制研究中的应用

姚开泰，何志巍，谢鹭，任彩萍，张玲

《中国病理生理杂志》

2000

c-myc gene inactivation during induction of nasopharyngeal carcinoma cells with retinoic acid

江宁，湛风凰，曹利，姚开泰，李桂源

《中华医学杂志(英文版)》

2000

一种简单、快速、高效的基因定点突变方法

任彩萍，刘卫东，何志巍，姚开泰

《中国细胞生物学学报》

2000

p53的两种结合蛋白:53BP1和53BP2

李虹，姚开泰

《医学分子生物学杂志》

2000

石蜡切片FISH技术应用于肿瘤组织的探讨

周文，谢鹭，姚开泰

《诊断病理学杂志》

1999

人鼻咽与鼻咽癌及肺癌基因表达谱差异的研究

何志巍，许亮国，任彩萍，谢鹭，甘润良，姚开泰

《生物化学与生物物理进展》

1999

间期FISH在鼻咽癌细胞系及石腊切片中的应用初探

谢鹭，周文，许亮国，杨旭宇，姚开泰

《癌症》

1999

用EBER-1作探针原位杂交检测鼻咽癌组织中的EB病毒

许亮国，陈曲侯，王珣章，姚开泰

《中华病理学杂志》

1999

人胚鼻咽上皮细胞培养、化学转化及鼻咽癌恶性转化基因的克隆

姚开泰，曹亚，陈主初，祝和成，胡维新，李韵萍，贺红

《医学研究杂志》

1999

DNA微阵列(或芯片)技术原理及应用

何志巍，姚开泰

《生物化学与生物物理进展》

1998

Point mutation of 2.8 kb EcoRI fragment of the NPC transforming gene in NPC cell lines

邓锡云，曹亚，曹莉，黎民敬，姚开泰

《中华医学杂志(英文版)》

1998

维甲酸对鼻咽癌细胞生长、表型和瘤基因表达的作用

江宁，曹利，张询，姚开泰，李桂源

《中国生物化学与分子生物学报》

1997

鼻咽癌中EBV DNA的原位检测及其意义的探讨

刘保安，蒋晓群，蔡杰，姚开泰

《诊断病理学杂志》

1997

二亚硝基哌嗪诱发转基因小鼠鼻咽上皮细胞恶性转化的研究

祝和成，曾庆华，黄柏英，顾焕华，马先勇，姚开泰

《中国病理生理杂志》

1997

鼻咽癌、宫颈癌和肺癌中p53基因突变和表达的对比研究

谢奕，姚开泰，胡维新

《中华病理学杂志》

1997

鼻咽癌病因学研究的现状与瞻望

姚开泰

《中国肿瘤》

1997

EB病毒BNLF-1基因的分子生物学研究进展

马先勇，曹亚，姚开泰

《生物化学与生物物理进展》

1997

DNase-1敏感区在人类有丝分裂中期染色体上的定位研究

李桂源，姚开泰，潘世成

《中国肿瘤》

1997

克隆羊技术在肿瘤研究中的意义

姚开泰

《中国肿瘤》

1996

Epstein-Barr病毒潜伏状态与鼻咽癌的关系

游绍进，姚开泰，曹亚，胡维新

《中华肿瘤杂志》

1996

EB病毒对人胚鼻咽上皮细胞的转化

贺智敏，陈主初，邵细云，何春梅，姚开泰

《中华病理学杂志》

1996

中国人鼻咽癌恶性转化基因的克隆及其生物物理性状研究

曹亚，邓锡云，胡维新，Leo M.Lee，陈孝光，贺红，李晓艳，姚开泰

《医学研究杂志》

1995

鼻咽癌研究的回顾与展望（纪念湖南医科大学80周年校庆）

姚开泰

《中南大学学报(医学版)》

1995

RECENT ADVANCES IN THE STUDY OF THE PATHOGENESIS OF NASOPHARYNGEAL CARCINOMA (NPC)

姚开泰

《中华医学杂志(英文版)》

1995

瘤基因和抑瘤基因表达和破坏在哺乳类发育和肿瘤形成中的作用

姚开泰

《实用肿瘤杂志》

1994

鼻咽癌恶性转化基因的克隆及其生物物理性状的研究

曹亚，胡维新，贺红，姚开泰

《中国肿瘤》

1994

瘤基因和抑瘤基因的表达和破坏在哺乳动物发育和肿瘤形成中的作用

姚开泰

《中国肿瘤》

1993

人类鼻咽癌细胞株CNE2的转化基因Tx的一个Eco RI片段的核苷酸序列分析

胡维新，曹亚，黎民敬，姚开泰

《中国生物化学与分子生物学报》

1993

酶联免疫电转移印迹技术(EITB)检测抗EB病毒特异性DNA酶抗体

田勇泉，彭勇炎，陶正德，肖健云，李韵萍，姚开泰

《中国现代医学杂志》

1993

人鼻咽上皮细胞株HNE-1染色体高分辨显带的研究

邓龙文，姚开泰

《癌症》

1993

人鼻咽癌上皮细胞株HNE-2细胞遗传学研究

邓龙文，祝和成，李桂源，姚开泰

《中华医学遗传学杂志》

1993

逆转录病毒载体介导的基因转移技术研究进展

马先勇，姚开泰

《医学分子生物学杂志》

1990

实验性大鼠鼻咽癌的病变观察

陈主初，潘世宬，姚开泰

《中国病理生理杂志》

1990

瘤基因研究的某些进展

姚开泰

《中国病理生理杂志》

1988

湖南省鼻咽癌高、低发区家庭烟尘中3,4—苯并芘含量测定

李桂源，罗慕强，尤家騄，姚开泰

《癌症》

1988

二亚硝基哌嗪诱发人胚鼻咽上皮姊妹染色单体交换的观察

李韵萍，姚开泰，胡友秋，潘世宬

《癌症》

1988

EB病毒研究的一些新进展

龙建平，姚开泰

《国外医学(微生物学分册)》

1987

抗癌药物杀伤瘤细胞群体和干细胞的研究(摘要)

彭力，姚开泰

《肿瘤学杂志》

1986

鼻咽癌患者外周血淋巴细胞染色体对化学致癌物的敏感性研究

李桂源，胡有秋，潘世宬，姚开泰

《中华医学遗传学杂志》

1982

从死因回顾调查资料看湖南省鼻咽癌流行病学的一些特点并探索其发病机理

姚开泰

《中南大学学报(医学版)》

精选作品

期刊论文

Tumor-Derived EBV-miR-BART2-5p Promotes Nasopharyngeal Carcinoma Metastasis by Inducing Premetastatic Endothelial Cell Pyroptosis

Data from Epstein-Barr Virus Induces Lymphangiogenesis and Lympth Node Metastasis via Upregulation of VEGF-C in Nasopharyngeal Carcinoma

Exosomal HMGA2 protein from EBV-positive NPC cells destroys vascular endothelial barriers and induces endothelial-to-mesenchymal transition to promote metastasis

Correction to: Casticin inhibits nasopharyngeal carcinoma growth by targeting phosphoinositide 3-kinase

A novel miR-200c/c-myc negative regulatory feedback loop is essential to the EMT process, CSC biology and drug sensitivity in nasopharyngeal cancer

Casticin inhibits nasopharyngeal carcinoma growth by targeting phosphoinositide 3-kinase

Publisher Correction: NOS1 S-nitrosylates PTEN and inhibits autophagy in nasopharyngeal carcinoma cells

利用CRISPR/Cas9技术建立NOD/SCID/IL2Rγ-/-免疫缺陷小鼠（英文）

A regulatory mutant on TRIM 26 conferring the risk of nasopharyngeal carcinoma by inducing low immune response

5T4-specific chimeric antigen receptor modification promotes the immune efficacy of cytokine-induced killer cells against nasopharyngeal carcinoma stem cell-like cells

A novel three‑dimensional tumorsphere culture system for the efficient and low‑cost enrichment of cancer stem cells with natural polymers

NOS1 S-nitrosylates PTEN and inhibits autophagy in nasopharyngeal carcinoma cells

Klf4 reduces stemness phenotype, triggers mesenchymal-epithelial transition (MET)-like molecular changes, and prevents tumor progression in nasopharygeal carcinoma

SPLUNC1基因在人体组织中的表达分布特征

Higher methylation intensity induced by EBV LMP1 via NF-κB/DNMT3b signaling contributes to silencing of PTEN gene

The important role of the receptor for activated C kinase 1 (RACK1) in nasopharyngeal carcinoma progression

Hes1 triggers epithelial-mesenchymal transition (EMT)-like cellular marker alterations and promotes invasion and metastasis of nasopharyngeal carcinoma by activating the PTEN/AKT pathway

Cytokine-induced killer cells efficiently kill stem-like cancer cells of nasopharyngeal carcinoma via the NKG2D-ligands recognition

A Fraction of CD133+ CNE2 Cells Is Made of Giant Cancer Cells with Morphological Evidence of Asymmetric Mitosis

甲基转移酶对鼻咽癌细胞中DLC-1基因表达的影响

鼻咽癌干细胞标志物的检测意义

姚开泰院士集

Effects of epigallocatechin gallate on the proliferation and apoptosis of the nasopharyngeal carcinoma cell line CNE2

Depletion of intermediate filament protein Nestin, a target of microRNA-940, suppresses tumorigenesis by inducing spontaneous DNA damage accumulation in human nasopharyngeal carcinoma

Aberrant CpG island methylation of PTEN is an early event in nasopharyngeal carcinoma and a potential diagnostic biomarker

Junctional adhesion molecule-A, an epithelial–mesenchymal transition inducer, correlates with metastasis and poor prognosis in human nasopharyngeal cancer

鼻咽癌组织中梭形癌细胞具有上皮-间充质转化及肿瘤干细胞特性

间质标志物巢蛋白在鼻咽癌中的表达及其临床意义

CDK4 mRNA在鼻咽癌的表达及临床意义

Cancer stem cell characteristics, ALDH1 expression in the invasive front of nasopharyngeal carcinoma

Cancer stem‐like cell properties are regulated by EGFR / AKT /β–catenin signaling and preferentially inhibited by gefitinib in nasopharyngeal carcinoma

Promoter hypermethylation along with LOH, but not mutation, contributes to inactivation of DLC‐1 in nasopharyngeal carcinoma

携带Fluc和ZsGreen双报告基因小鼠iPS细胞系的建立

MTA1 contributes to actin cytoskeleton reorganization and metastasis of nasopharyngeal carcinoma by modulating Rho GTPases and Hedgehog signaling

EBV-miR-BART1 is involved in regulating metabolism-associated genes in nasopharyngeal carcinoma

Molecular Characterization and Clinical Implications of Spindle Cells in Nasopharyngeal Carcinoma: A Novel Molecule-Morphology Model of Tumor Progression Proposed

Correction: Embryonic Stem Cells Markers SOX2, OCT4 and Nanog Expression and Their Correlations with Epithelial-Mesenchymal Transition in Nasopharyngeal Carcinoma

Radioactive 125I Seed Inhibits the Cell Growth, Migration, and Invasion of Nasopharyngeal Carcinoma by Triggering DNA Damage and Inactivating VEGF-A/ERK Signaling

Erratum: Loss of connective tissue growth factor as an unfavorable prognosis factor activates miR-18b by PI3K/AKT/C-Jun and C-Myc and promotes cell growth in nasopharyngeal carcinoma

Over-expression of BCAT1, a c-Myc target gene, induces cell proliferation, migration and invasion in nasopharyngeal carcinoma

Loss of connective tissue growth factor as an unfavorable prognosis factor activates miR-18b by PI3K/AKT/C-Jun and C-Myc and promotes cell growth in nasopharyngeal carcinoma

Embryonic Stem Cells Markers SOX2, OCT4 and Nanog Expression and Their Correlations with Epithelial-Mesenchymal Transition in Nasopharyngeal Carcinoma

miR-9 modulates the expression of interferon-regulated genes and MHC class I molecules in human nasopharyngeal carcinoma cells

Neoplastic spindle cells in nasopharyngeal carcinoma possess properties of epithelial-mesenchymal transition and cancer stem cells

Expression of a mesenchymal marker N-cadherin in nasopharyngeal carcinoma and its clinical significance

以肿瘤干细胞为靶的免疫治疗

携人PTHLH基因慢病毒表达载体的构建

MYC Regulation of CHK1 and CHK2 Promotes Radioresistance in a Stem Cell-like Population of Nasopharyngeal Carcinoma Cells

Further evidence for the existence of major susceptibility of nasopharyngeal carcinoma in the region near HLA-A locus in Southern Chinese

红色荧光蛋白和荧光素酶双报告基因转基因小鼠的建立

慢病毒载体法制备荧光素酶转基因小鼠

携带Oct4、Klf4、Sox2、c-myc和EGFP基因小鼠肿瘤细胞株的建立

Aldehyde dehydrogenase 1, a functional marker for identifying cancer stem cells in human nasopharyngeal carcinoma

Tumour budding and the expression of cancer stem cell marker aldehyde dehydrogenase 1 in nasopharyngeal carcinoma

Overexpressed DNA-binding protein inhibitor 2 as an unfavorable prognosis factor promotes cell proliferation in nasopharyngeal carcinoma

Neoplastic spindle cells in nasopharyngeal carcinoma show features of epithelial–mesenchymal transition

High Expression of Nuclear Snail, but not Cytoplasmic Staining, Predicts Poor Survival in Nasopharyngeal Carcinoma

Nuclear expression of N‐cadherin correlates with poor prognosis of nasopharyngeal carcinoma

Aberrant expression of nuclear vimentin and related epithelial–mesenchymal transition markers in nasopharyngeal carcinoma

鼻咽癌细胞株5-8F-EGFP和肝转移亚群5-8F-H3B-EGFP的基因表达谱分析

Q-RT-PCR检测LAMC2、KLK6、SNCG在鼻咽癌肝转移细胞中的表达

慢病毒载体介导的RNAi技术构建稳定抑制β-catenin的人鼻咽癌细胞株

加强推进力度,促进转化医学发展

人诱导性多潜能干细胞(iPS细胞)系的建立

携带人c-Myc和EGFP基因慢病毒表达载体的构建

Potential Tumor Suppressor NESG1 as an Unfavorable Prognosis Factor in Nasopharyngeal Carcinoma

Construction of a stable human nasopharyngeal carcinoma cell line with down-regulated expression of β-catenin

Underlying mechanisms for LTF inactivation and its functional analysis in nasopharyngeal carcinoma cell lines

MiR-26a Inhibits Cell Growth and Tumorigenesis of Nasopharyngeal Carcinoma through Repression of EZH2

转录因子Snail及黏附分子E-cadherin在鼻咽癌中的表达

鼻咽癌EMT相关基因的筛选及生物信息学分析

鼻咽癌细胞株侧群细胞染色条件的优化及其表面标记物的测定

佛波醇脂和溴脱氧尿嘧啶核苷促进鼻咽癌细胞中CD133的表达

鼻咽癌细胞系候选癌基因的筛选

原位鼻咽癌裸鼠模型血清蛋白质组学的研究

鼻咽癌细胞株中标记滞留细胞(LRGs)的建立与检测(英文)

慢病毒载体法制备红色荧光蛋白转基因小鼠

Screening of nasopharyngeal carcinoma EMT-related genes and their bioinformatics analysis.