丁陈波｜重庆医科大学｜学者主页

2026

Nat10-mediated ac4C modification sustains macrophage proliferation and mitigates colitis progression via Mcm2 stabilization

Jinsong Wang, Tao Liu, Jiachen Zhao, Zhiqing Diao, Fuhong Fan, Demeng Qin, Yu Zhang, Xindi Wang, Ning Jiang, Chenbo Ding, Huabing Li, Yuzhang Wu

Science China Life Sciences

DOI

2026

Blocking the m6Am methyltransferase PCIF1 in macrophages attenuates colitis progression by preventing neuronal damage

Chenbo Ding, Jiachen Zhao, Tian Zhao, Ye Xiao, Kai Li, Xiao Liu, Xuyang Ge, Demeng Qin, Zhiqian Huang, Yu Zhang, Hua Liu, Zhiqing Diao, Youqiong Ye, Richard Anthony Flavell, Cheng Luo, Shijie Chen, Chengqi Yi, Zhengting Wang, Huabing Li

Cellular and Molecular Immunology

DOI

2026

Blocking the m6Am methyltransferase PCIF1 releases STAT1-mediated Th1 immunity to potentiate cancer immunotherapy

Jiansong Huang, Jing Zhou, Xiao Liu, Xiaoxu Liu, Ye Xiao, Kai Li, Chenbo Ding, Xuemin Cai, Wenli Mao, Changfen Xu, Yuxin Kong, Yu Deng, Xiaohan Song, Mei Yang, Daohai Du, Siqi Guo, Kaixian Chen, Cheng Luo, Chengqi Yi, Shijie Chen, Huabing Li

Nature Communications

DOI

2025

METTL3 modulates colonic epithelium integrity via maintaining the self-renewal and differentiation of Lgr5+ stem cell

Chenbo Ding, Xinhui Yang, Hua Liu, Manolis Roulis, Huifang Chen, Yunzhu Chen, Hao Ying Xu, Yimeng Gao, Jie Zhong, Huabing Li, Youqiong Ye, Wei Cai, Weiguo Hu, Zhengting Wang

Journal of Molecular Cell Biology

DOI

2024

The crosstalk between enteric nervous system and immune system in intestinal development, homeostasis and diseases

Xindi Wang, Chenbo Ding, Hua-Bing Li

Science China Life Sciences

2023

A Treg-specific long noncoding RNA maintains immune-metabolic homeostasis in aging liver

Chen-Bo Ding, Zhibin Yu, Esen Sefik, Jing Zhou, E. Kaffe, Gaoyang Wang, Bin Li, R. Flavell, Weiguo Hu, You-Qiong Ye, Hua-Bing Li

Nature Aging

DOI

2023

N6‐ Methyladenosine defines a new checkpoint in γδ T cell development

Jia-Cheng Zhao, Chen-Bo Ding, Hua-Bing Li

Bioessays

DOI

2022

m6A mRNA modification maintains colonic epithelial cell homeostasis via NF-κB–mediated antiapoptotic pathway

Ting Zhang, Chen-Bo Ding, Hui-Fang Chen, Jun Zhao, Zhejun Chen, Bai-Wen Chen, Kaiqiong Mao, Yajuan Hao, M. Roulis, Hao Xu, Y. Kluger, Qiang Zou, Youqiong Ye, Mei-Xiao Zhan, R. Flavell, Hua-Bing Li

Science Advances

DOI

2021

m6A demethylase ALKBH5 controls CD4+ T cell pathogenicity and promotes autoimmunity

Jing Zhou, Xingli Zhang, Jia-Jia Hu, Rihao Qu, Zhi-Bin Yu, Hao Xu, Hui-Fang Chen, Li-chong Yan, Chen-Bo Ding, Qiang Zou, Youqiong Ye, Zheng-Ting Wang, R. Flavell, Hua-Bing Li

Science Advances

DOI

2020

RNA m6A demethylase ALKBH5 regulates the development of γδ T cells

R. Flavell, Chen-Bo Ding, Zhi-Bin Yu, Hao Xu, M. Roulis, Rihao Qu, Jing Zhou, Abigail Jarret, Ruaidhri Jackson, Zheng Wei, Yimeng Gao, Mathias H. Skadow, Esen Sefik, Z. Yin, Qiang Zou, Bing Su, Q. Xia, Hua-Bing Li

DOI

丁陈波

精选作品

期刊论文

Nat10-mediated ac4C modification sustains macrophage proliferation and mitigates colitis progression via Mcm2 stabilization

Blocking the m6Am methyltransferase PCIF1 in macrophages attenuates colitis progression by preventing neuronal damage

Blocking the m6Am methyltransferase PCIF1 releases STAT1-mediated Th1 immunity to potentiate cancer immunotherapy

METTL3 modulates colonic epithelium integrity via maintaining the self-renewal and differentiation of Lgr5+ stem cell

The crosstalk between enteric nervous system and immune system in intestinal development, homeostasis and diseases

A Treg-specific long noncoding RNA maintains immune-metabolic homeostasis in aging liver

N6‐ Methyladenosine defines a new checkpoint in γδ T cell development

m6A mRNA modification maintains colonic epithelial cell homeostasis via NF-κB–mediated antiapoptotic pathway

m6A demethylase ALKBH5 controls CD4+ T cell pathogenicity and promotes autoimmunity

RNA m6A demethylase ALKBH5 regulates the development of γδ T cells

研究方向