黄剑东｜福州大学｜学者主页

2026

Synchronized co-delivery of type I photosensitizer and immunomodulator via tumor-pH-responsive nanoliposome for photodynamic immunotherapy

Ling Zhang, Xiaojuan Huang, Mei‐Rong Ke, Bi-Yuan Zheng, Ying Xie, Jian‐Dong Huang

Materials Today Chemistry

2026

Identifying Structural Factors Governing the Photodynamic Activity of Phthalocyanines

Magdaléna Kozlíková, Mary Angelia Alfred, Miloslav Macháček, Fabienne Dumoulin, Andrés de la Escosura, Tomasz Adam Gośliński, Marie Halašková, Jian‐Dong Huang, Mei‐Rong Ke, Saad Makhseed, Dariusz T. Młynarczyk, Dennis K. P. Ng, Tomás Torres⊗, Roy C. H. Wong, Petr Zimčík, Veronika Novakova

Journal of Medicinal Chemistry

精选作品

期刊论文

Synchronized co-delivery of type I photosensitizer and immunomodulator via tumor-pH-responsive nanoliposome for photodynamic immunotherapy

Identifying Structural Factors Governing the Photodynamic Activity of Phthalocyanines

Multienzyme-mimicking nano photosensitizer based on Manganese(III) phthalocyanine for tumor photoacoustic imaging and chemo-photodynamic combination therapy

Phthalocyanine-based prodrug with H₂S-triggered domino cascade for photodynamic and multiple-mechanism synergistic anti-metastatic therapy

用于组合光疗的两亲性单取代锌酞菁J聚集纳米粒

Preparation and Performance of Phthalocyanine @ Copper Iodide Cluster Nanoparticles for X-Ray-Induced Photodynamic Therapy

Phthalocyanine-based nanosensitizers for enhanced sonodynamic therapy activity of hypoxic tumor with dual apoptosis/ferroptosis pathways

Phthalocyanine aggregates as semiconductor-like photocatalysts for hypoxic-tumor photodynamic immunotherapy

具有肿瘤靶向的铜碘簇纳米粒用于X射线诱导光动力疗法（英文）

Molecular Design of Phthalocyanine-Based Drug Coassembly with Tailored Function

A tumor-pH-responsive phthalocyanine as activatable type I photosensitizer for improved photodynamic immunotherapy

N-bridging tetra-substituted zinc(II) phthalocyanines with Q-band absorption up to 780 nm and eminent photosensitizing activities for photodynamic therapy

Facile Synthesis of Novel Ti2C Nano Bipyramids for Photothermal and Photodynamic Therapy of Breast Cancer

制药工程实验教程

A self-degradable nanostructured phthalocyanine assembly with high photothermal efficacy to enhanced biosecurity in photothermal therapy

Synthesis, characterization and photodynamic antitumor activity of amine-modified zinc (II) phthalocyanines

A Sulfur-Bridging Sulfonate-Modified Zinc(II) Phthalocyanine Nanoliposome Possessing Hybrid Type I and Type II Photoreactions with Efficient Photodynamic Anticancer Effects

Synthesis and photothermal/photodynamic antimicrobial activities of phthalocyanines tetra-substituted by morpholinyl moieties

A smart and visible way to switch the aromaticity of silicon( iv ) phthalocyanines

Glu-Urea-Lys Scaffold Functionalized Superparamagnetic Iron Oxide Nanoparticles Targeting PSMA for In Vivo Molecular MRI of Prostate Cancer

Programmable phthalocyanine-iron-based nanoreactor for fluorescence/magnetic resonance dual-modality imaging-guided sono/chemodynamic therapies

Thermosensitive Liposomal Nanoplatform Based on Metal‐Free Phthalocyanine with Copper(II)‐Regulated Photoactivities

Nanostructured self-assemblies of photosensitive dyes: green and efficient theranostic approaches

Molecular and Supramolecular Approach to Highly Photocytotoxic Phthalocyanines with Dual Cell Uptake Pathways and Albumin-Enhanced Tumor Targeting

Frontispiece: Aggregation‐Enhanced Sonodynamic Activity of Phthalocyanine–Artesunate Conjugates

Frontispiz: Aggregation‐Enhanced Sonodynamic Activity of Phthalocyanine–Artesunate Conjugates

Solid-state supramolecular structures and excellent photothermal activities of dimeric zinc(II) phthalocyanines axially bridged with bipyridine derivatives

Aggregation‐Enhanced Sonodynamic Activity of Phthalocyanine–Artesunate Conjugates

Nanostructured Phthalocyanine Assemblies with Efficient Synergistic Effect of Type I Photoreaction and Photothermal Action to Overcome Tumor Hypoxia in Photodynamic Therapy

The substituted zinc(II) phthalocyanines using “sulfur bridge” as the linkages. Synthesis, red-shifted spectroscopic properties and structure-inherent targeted photodynamic activities

A phthalocyanine-based self-assembled nanophotosensitizer for efficient in vivo photodynamic anticancer therapy

A pH-sensitive nanoagent self-assembled from a highly negatively-charged phthalocyanine with excellent biosafety for photothermal therapy

制药工程专业核心课程工业药剂学的教学改革探索与实践

制药工程专业生物化学实验课程的建设与探索

Synthesis, Spectroscopic Properties, and Photodynamic Anticancer Activities of Novel Arginine-modified Silicon(Ⅳ) Phthalocyanines

羧基单取代酞菁锌的合成与光动力抗癌活性

A non-aggregated zinc(II) phthalocyanine with hexadeca cations for antitumor and antibacterial photodynamic therapies

Artesunate-Based Multifunctional Nanoplatform for Photothermal/Photoinduced Thermodynamic Synergistic Anticancer Therapy

Phthalocyanine-based photosensitizers combined with anti-PD-L1 for highly efficient photodynamic immunotherapy

A phthalocyanine-based liposomal nanophotosensitizer with highly efficient tumor-targeting and photodynamic activity

Alginate-zinc (II) phthalocyanine conjugates: Synthesis, characterization and tumor-associated macrophages-targeted photodynamic therapy

Noncovalent Indocyanine Green Conjugate of C-Phycocyanin: Preparation and Tumor-Associated Macrophages-Targeted Photothermal Therapeutics

A non-aggregated silicon(IV) phthalocyanine-lactose conjugate for photodynamic therapy

Novel unsymmetrical silicon(IV) phthalocyanines as highly potent anticancer photosensitizers. Synthesis, characterization, and in vitro photodynamic activities

Carboxymethyl chitosan-zinc(II) phthalocyanine conjugates: Synthesis, characterization and photodynamic antifungal therapy

工程教育专业认证背景下制药工程专业实验课程改革

基于成果导向的制药工程专业实验教学改革实践

基于成果导向教育的制药工艺学教学改革探索

Size-Tunable Targeting-Triggered Nanophotosensitizers Based on Self-Assembly of a Phthalocyanine–Biotin Conjugate for Photodynamic Therapy

A novel silicon(IV) phthalocyanine-oligopeptide conjugate as a highly efficient photosensitizer for photodynamic antimicrobial therapy

可激活抗癌光敏剂

基于毕业能力培养的制药分离工程教学改革探索

四磺化酞菁锌与白蛋白复合物的制备、光谱性质与光动力活性研究

In Vivo Albumin Traps Photosensitizer Monomers from Self-Assembled Phthalocyanine Nanovesicles: A Facile and Switchable Theranostic Approach

A pH-responsive stellate mesoporous silica based nanophotosensitizer for in vivo cancer diagnosis and targeted photodynamic therapy

Preparation and antifungal properties of monosubstituted zinc(П) phthalocyanine-chitosan oligosaccharide conjugates and their quaternized derivatives

Phthalocyanine‐Assembled Nanodots as Photosensitizers for Highly Efficient Type I Photoreactions in Photodynamic Therapy

Synthesis and photodynamic activities of integrin-targeting silicon(IV) phthalocyanine-cRGD conjugates

Progress in the development of nanosensitizers for X-ray-induced photodynamic therapy

Synthesis, Spectroscopic and Fibroblast Activation Protein (FAP)‐Responsive Properties of Phthalocyanine‐Doxorubicin Conjugates

Synthesis and biological characterization of novel rose bengal derivatives with improved amphiphilicity for sono-photodynamic therapy

New application of phthalocyanine molecules: from photodynamic therapy to photothermal therapy by means of structural regulation rather than formation of aggregates

Phthalocyanines as medicinal photosensitizers: Developments in the last five years

Highly photocytotoxic silicon(IV) phthalocyanines axially modified with l-tyrosine derivatives: Effects of mode of axial substituent connection and of formulation on photodynamic activity

A Tumor-pH-Responsive Supramolecular Photosensitizer for Activatable Photodynamic Therapy with Minimal In Vivo Skin Phototoxicity

C-Phycocyanin as a tumour-associated macrophage-targeted photosensitiser and a vehicle of phthalocyanine for enhanced photodynamic therapy

A tumor-targeted activatable phthalocyanine-tetrapeptide-doxorubicin conjugate for synergistic chemo-photodynamic therapy

Comparison between amine-terminated phthalocyanines and their chlorambucil conjugates: Synthesis, spectroscopic properties, and in vitro anticancer activity

Silicon(IV) phthalocyanines substituted axially with different nucleoside moieties. Effects of nucleoside type on the photosensitizing efficiencies and in vitro photodynamic activities

Mono- and tetra-substituted zinc(II) phthalocyanines containing morpholinyl moieties: Synthesis, antifungal photodynamic activities, and structure-activity relationships

The effects of formulation and serum albumin on the in vitro photodynamic activity of zinc(II) phthalocyanines substituted with sulfonated quinolineoxy groups

轴向核苷修饰硅酞菁与白蛋白非共价复合物的制备与光动力活性

Study of the Edge-on Self-Assembly of Axially Substituted Silicon(IV) Phthalocyanine Derivatives in a Template on the HOPG Surface

Highly positive-charged zinc(II) phthalocyanine as non-aggregated and efficient antifungal photosensitizer

A pH‐Responsive Layered Double Hydroxide (LDH)–Phthalocyanine Nanohybrid for Efficient Photodynamic Therapy

A non-aggregated and tumour-associated macrophage-targeted photosensitiser for photodynamic therapy: a novel zinc( ii ) phthalocyanine containing octa-sulphonates

Potential sonodynamic anticancer activities of artemether and liposome-encapsulated artemether

Novel silicon(IV) phthalocyanines containing piperidinyl moieties: Synthesis and in vitro antifungal photodynamic activities