丰明乾｜华中农业大学｜学者主页

2026

Correction: A robust and scalable immunoadsorbent platform based on the high-affinity M03-IgG antibody for targeted IL-6 Removal in cytokine storm

Yaxi Yang, Lei Wan, Youjia Qin, Jiangtao Guo, Yong Wang, Kangkang Ji, Sheng Hu, Mingqian Feng

Frontiers in Immunology

DOI

2026

A robust and scalable immunoadsorbent platform based on the high-affinity M03-IgG antibody for targeted IL-6 Removal in cytokine storm

Yaxi Yang, Lei Wan, Youjia Qin, J Z Guo, Yong Wang, Kangkang Ji, Sheng Hu, Mingqian Feng

Frontiers in Immunology

DOI

2025

A conceptual exploration on the synergistic anti-tumor effects of high-order combination of OHSV2-DSTEFAP5/CD3, CAR-T cells, and immunotoxins in hepatocellular carcinoma

Shuang Dong, Xin Chen, Xiaoyu Li, Yang Wang, Qing Huang, Yuanxiang Li, Jing Jin, Xianmin Zhu, Yi Zhong, Qian Cai, Chang Xue, Fang Guo, Le Huang, Mingqian Feng, Binlei Liu, Sheng Hu

Frontiers in Immunology

DOI

2025

Dual T/NK cell engagement via B7-H6-targeted bispecific antibodies and IL-15 eradicates chemo-resistant solid tumors

Xuqian Ma, Huixia He, Yuankui Zhu, Dianbao Zuo, Fanglin Wang, Mingqian Feng, Kangkang Ji, Xin Chen

Frontiers in Immunology

DOI

2025

Targeting CD16A on NK cells and GPC3 in hepatocellular carcinoma: development and functional validation of a therapeutic bispecific antibody

Liu Chen, Yuankui Zhu, Mingqian Feng, Dianbao Zuo, Guoping Chen, Kangkang Ji

Frontiers in Immunology

DOI

2025

Harnessing delta-like ligand 3: bridging biomarker discovery to next-generation immunotherapies in refractory small cell lung cancer

Kangkang Ji, Lin Guo, Dianbao Zuo, Mingqian Feng, Xin Chen, Zhenggang Zhao, Jing Ping Tang, Guoping Chen

Frontiers in Immunology

DOI

2025

Single-cell sequencing reveals the expansion and diversity of T cell subsets in the bone marrow microenvironment of chronic myeloid leukemia

Chenjian Zhuo, Xin Dong, Xueya Zhao, Weiru Wu, Hao Zhou, Jing Feng, Lingbo Liu, Mingqian Feng, Chunjiang He, Yu Hou

Genes & Diseases

DOI

2025

Efficacy of natural killer T and gammadelta T cells in mesothelin-targeted immunotherapy of pancreatic cancer

Yuankui Zhu, Yaxi Yang, Linghe Yue, Lei Wan, Xuqian Ma, Qing X. Yang, Xuan Tian, Yuguan Li, Xiuli Wang, Shaozhong Wei, Dianbao Zuo, Mingqian Feng

Frontiers in Immunology

DOI

2024

Mesothelin CAR-T cells expressing tumor-targeted immunocytokine IL-12 yield durable efficacy and fewer side effects

Yuankui Zhu, Xiuli Wang, Linghe Yue, Dianbao Zuo, Junfeng Sheng, Sina Lan, Zilong Zhao, Shuang Dong, Sheng Shou Hu, Xin Chen, Mingqian Feng

Pharmacological Research

DOI

2024

A novel LAG3 neutralizing antibody improves cancer immunotherapy by dual inhibition of MHC-II and FGL1 ligand binding

Dianbao Zuo, Yuankui Zhu, Xiuli Wang, Youjia Qin, Yiyi Su, Sina Lan, Yunyi Li, Shuang Dong, Yinming Liang, Mingqian Feng

Biomedicine & Pharmacotherapy

DOI

2024

Genetically Modified Hepatocytes Targeting Bilirubin and Ammonia Metabolism for the Construction of Bioartificial Liver System

Ke Wang, Yuankui Zhu, Mengqing Li, Yaxi Yang, Dianbao Zuo, Junfeng Sheng, Xinhai Zhang, Wei J. Wang, Zhou Ping, Mingqian Feng

Biomaterials Research

DOI

2023

Mesothelin-targeted CAR-T therapy combined with irinotecan for the treatment of solid cancer

Yuankui Zhu, Dianbao Zuo, Xiuli Wang, Sina Lan, Huixia He, Liu Chen, Xin Chen, Mingqian Feng

Journal of Cancer Research and Clinical Oncology

DOI

2023

Immunotherapy of Epstein-Barr virus (EBV) infection and EBV-associated hematological diseases with gp350/CD89-targeted bispecific antibody

Huixia He, Feifei Lei, Le Huang, Xiuli Wang, Yaxi Yang, Liu Chen, Yun Feng Peng, Yinming Liang, Huabing Tan, Xiaoyan Wu, Mingqian Feng

Biomedicine & Pharmacotherapy

DOI

2022

EGFRvⅢ-targeted immunotoxin combined with temozolomide and bispecific antibody for the eradication of established glioblastoma

Le Huang, Huixia He, Ke Wang, Xuqian Ma, Xin Chen, Wenxin Chen, Xuan Wang, Xiaobing Jiang, Mingqian Feng

Biomedicine & Pharmacotherapy

DOI

2022

Strengthening of antitumor effects in breast cancer from a novel B7-H4- and CD3-targeting bispecific antibody by an oncolytic virus

Jing Ping Tang, Xuqian Ma, Xin Chen, Mingqian Feng, Xin Jin, Ke Wang, Jixi Wan, Xianmin Zhu, Rong Xie, Shuang Dong, Sheng Chuan Hu, Hui Jiang, Conghua Xie

Annals of Translational Medicine

DOI

2022

Highly Potent Immunotoxins Targeting the Membrane-distal N-lobe of GPC3 for Immunotherapy of Hepatocellular Carcinoma

Jingwen Li, Lanxin Xiang, Qian Wang, Xuqian Ma, Xin Chen, Yuankui Zhu, Yaxi Yang, Le Huang, Huixia He, Lilei Xu, Xinjun Liang, Shuang Dong, Sheng Chuan Hu, Hanjie Li, Mingqian Feng

Journal of Cancer

DOI

2021

Combination Therapy of Hepatocellular Carcinoma by GPC3-Targeted Bispecific Antibody and Irinotecan is Potent in Suppressing Tumor Growth in Mice

Xin Chen, Yanmin Chen, Rong Liang, Lanxin Xiang, Jingwen Li, Yuankui Zhu, Huixia He, Le Huang, Dianbao Zuo, Weihang Li, Xinjun Liang, Shuang Dong, Sheng Hu, Mitchell Ho, Mingqian Feng

Molecular Cancer Therapeutics

DOI

2021

Generation of TIM3 inhibitory single‑domain antibodies to boost the antitumor activity of chimeric antigen receptor T cells

Liu Yang, Xin Chen, Qian Wang, Yuankui Zhu, Changfa Wu, Xuqian Ma, Dianbao Zuo, Huixia He, Le Huang, Jing Li, Chunjiao Xia, Sheng Hu, Xiaoqing Yang, Mingqian Feng

Oncology Letters

DOI

2021

Identification of the atypical cadherin FAT1 as a novel glypican-3 interacting protein in liver cancer cells

Panpan Meng, Yifan Zhang, Wangli Zhang, Xin Chen, Tong Xu, Sheng Hu, Xinjun Liang, Mingqian Feng, Xiaoqing Yang, Mitchell Ho

Scientific Reports

DOI

2020

Combined DLL3-targeted bispecific antibody with PD-1 inhibition is efficient to suppress small cell lung cancer growth

Xin Chen, Norhan Amar, Yuankui Zhu, Chunguang Wang, Chunjiao Xia, Xiaoqing Yang, Dongde Wu, Mingqian Feng

Journal for ImmunoTherapy of Cancer

DOI

2019

A Frizzled‐Like Cysteine‐Rich Domain in Glypican‐3 Mediates Wnt Binding and Regulates Hepatocellular Carcinoma Tumor Growth in Mice

Na Li, Liwen Wei, Xiaoyu Liu, Hongjun Bai, Yvonne Ye, Dan Li, Nan Li, Ulrich Baxa, Qun Wang, Ling Lv, Yun Chen, Mingqian Feng, Byungkook Lee, Wei Gao, Mitchell Ho

Hepatology

DOI

丰明乾

精选作品

期刊论文

Correction: A robust and scalable immunoadsorbent platform based on the high-affinity M03-IgG antibody for targeted IL-6 Removal in cytokine storm

A robust and scalable immunoadsorbent platform based on the high-affinity M03-IgG antibody for targeted IL-6 Removal in cytokine storm

A conceptual exploration on the synergistic anti-tumor effects of high-order combination of OHSV2-DSTEFAP5/CD3, CAR-T cells, and immunotoxins in hepatocellular carcinoma

Dual T/NK cell engagement via B7-H6-targeted bispecific antibodies and IL-15 eradicates chemo-resistant solid tumors

Targeting CD16A on NK cells and GPC3 in hepatocellular carcinoma: development and functional validation of a therapeutic bispecific antibody

Harnessing delta-like ligand 3: bridging biomarker discovery to next-generation immunotherapies in refractory small cell lung cancer

Single-cell sequencing reveals the expansion and diversity of T cell subsets in the bone marrow microenvironment of chronic myeloid leukemia

Efficacy of natural killer T and gammadelta T cells in mesothelin-targeted immunotherapy of pancreatic cancer

Mesothelin CAR-T cells expressing tumor-targeted immunocytokine IL-12 yield durable efficacy and fewer side effects

A novel LAG3 neutralizing antibody improves cancer immunotherapy by dual inhibition of MHC-II and FGL1 ligand binding

Genetically Modified Hepatocytes Targeting Bilirubin and Ammonia Metabolism for the Construction of Bioartificial Liver System

Mesothelin-targeted CAR-T therapy combined with irinotecan for the treatment of solid cancer

Immunotherapy of Epstein-Barr virus (EBV) infection and EBV-associated hematological diseases with gp350/CD89-targeted bispecific antibody

EGFRvⅢ-targeted immunotoxin combined with temozolomide and bispecific antibody for the eradication of established glioblastoma

Strengthening of antitumor effects in breast cancer from a novel B7-H4- and CD3-targeting bispecific antibody by an oncolytic virus

Highly Potent Immunotoxins Targeting the Membrane-distal N-lobe of GPC3 for Immunotherapy of Hepatocellular Carcinoma

Combination Therapy of Hepatocellular Carcinoma by GPC3-Targeted Bispecific Antibody and Irinotecan is Potent in Suppressing Tumor Growth in Mice

Generation of TIM3 inhibitory single‑domain antibodies to boost the antitumor activity of chimeric antigen receptor T cells

Identification of the atypical cadherin FAT1 as a novel glypican-3 interacting protein in liver cancer cells

Combined DLL3-targeted bispecific antibody with PD-1 inhibition is efficient to suppress small cell lung cancer growth

A Frizzled‐Like Cysteine‐Rich Domain in Glypican‐3 Mediates Wnt Binding and Regulates Hepatocellular Carcinoma Tumor Growth in Mice

研究方向