孟卓群｜西华大学｜学者主页

2026

Sinensetin ameliorates established high-fat diet-induced liver injury and intestinal barrier dysfunction through the mitophagy/TLR4/MAPK signaling pathway

Zhuoqun Meng, Qin Zhang, Zhichao Zhao, Yuan Zhang, Zhijie Lu, Guirong Liu, Wenliang Xiang, Qing Zhang, Jie Tang

Frontiers in Nutrition

DOI

2025

Mechanisms of apigenin in mitigating APAP-induced hepatocyte pyroptosis and liver injury via TRPV4 activation and ESCRT-mediated membrane repair

Zhuoqun Meng, Shuang Guan, Ran-Ran Zhang, Chun-Yun Wang, Xu-Ming Deng, Jing Lu

Food Science and Human Wellness

DOI

2025

Protective effects of sinensetin on intestinal barrier damage induced by lipopolysaccharide in mice through TLR4/NLRP3/GSDMD pathway

Zhuoqun Meng, Qin Zhang, Ran-Ran Zhang, Guirong Liu, Wenliang Xiang, Yang He, Qing Zhang, Jie Tang

Journal of Agriculture and Food Research

DOI

2025

Sinensetin Ameliorates Lipopolysaccharide-Induced Liver Injury by Targeting the TLR4/NF-κB/NLRP3 Pathway and Related Gut-Liver Axis Dysfunction in Mice.

Zhuoqun Meng, Qin Zhang, Ran-Ran Zhang, Guirong Liu, Wenliang Xiang, Yang He, Qing Zhang, Jie Tang

Journal of Agricultural and Food Chemistry

DOI

2024

Apigenin ameliorated ferroptosis induced by high-fat-diet via suppressing lysosome iron efflux in hepatocytes

Zhuoqun Meng, Jing Lu, Min Gao, Ran-Ran Zhang, Hongjiang Zhou, Shanshan Chen, Xu-Ming Deng, Shuang Guan

Food Science and Human Wellness

DOI

2024

Apigenin Reduces Lipid Droplet Accumulation in Hepatocytes by Enhancing Chaperone-Mediated Autophagy via AMPK.

Jing Lu, Hongjiang Zhou, Jin-Ping Hu, Ran-Ran Zhang, Zhuoqun Meng, Shuang Guan

Journal of Agricultural and Food Chemistry

DOI

2024

Proanthocyanidins alleviate acute alcohol liver injury by inhibiting pyroptosis via inhibiting the ROS-MLKL-CTSB-NLRP3 pathway.

Yingli Jin, Chun-Yun Wang, Zhuoqun Meng, Yuxin Zhang, Desen Meng, Jiaqi Liu, Meng Yuan, Shuang Guan

Phytomedicine

DOI

2024

Ginsenoside Rb1 alleviates 3-MCPD-induced renal cell pyroptosis by activating mitophagy.

Ran-Ran Zhang, Shuang Guan, Zhuoqun Meng, Duo-Duo Zhang, Jing Lu

Food and Chemical Toxicology

DOI

2024

3-MCPD Induces Renal Cell Pyroptosis and Inflammation by Inhibiting ESCRT-III-Mediated Cell Repair and Mitophagy.

Ran-Ran Zhang, Shuang Guan, Zhuoqun Meng, Xu-Ming Deng, Jing Lu

Journal of Agricultural and Food Chemistry

DOI

2023

芹菜素激活自噬缓解高脂饮食所致肝损伤的作用机制研究

孟卓群

《吉林大学》

2023

Apigenin Alleviated High-Fat-Diet-Induced Hepatic Pyroptosis by Mitophagy-ROS-CTSB-NLRP3 Pathway in Mice and AML12 Cells.

Zhuoqun Meng, Min Gao, Chun-Yun Wang, S. Guan, Duo-Duo Zhang, Jing Lu

Journal of Agricultural and Food Chemistry

DOI

2023

Ginsenoside Rb1 induces autophagic lipid degradation via miR-128 targeting TFEB.

Zhuoqun Meng, Jianing Lu, Guang-Yan Ge, Guang Wang, Ran Zhang, Yuhan Li, S. Guan, Jing Lu

Food & Function

DOI

2022

1,3‐Dichloro‐2‐propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes

S. Guan, Ran-Ran Zhang, Yanan Zhao, Zhuoqun Meng, Jing Lu

Environmental Toxicology

DOI

2022

Apigenin alleviated PA-induced pyroptosis by activating autophagy in hepatocytes.

Zhuoqun Meng, Bei-Wei Zhu, Min Gao, Guang Wang, Hongjiang Zhou, Jing Lu, S. Guan

Food & Function

DOI

2020

Apigenin induced autophagy and stimulated autophagic lipid degradation.

Jing Lu, Zhuoqun Meng, Yan Chen, L. Yu, Bo-Yan Gao, Yangjie Zheng, S. Guan

Food & Function

DOI

2019

Apigenin reduces the excessive accumulation of lipids induced by palmitic acid via the AMPK signaling pathway in HepG2 cells

Jing Lu, Zhuoqun Meng, Bi-Jun Cheng, Mei-Tong Liu, Siyu Tao, S. Guan

Experimental and Therapeutic Medicine

DOI

2018

Alliin attenuates 1, 3‐dichloro‐2‐propanol‐induced lipogenesis in HepG2 cells through activation of the AMP‐activated protein kinase‐dependent pathway

Jing Lu, Bi-Jun Cheng, Zhuoqun Meng, Baochen Fang, Tian-Jiao Li, Mao-Cheng Sun, Mei-Tong Liu, S. Guan

Life Science

DOI

2018

1,3-Dichloro-2-Propanol inhibits autophagy via P53/AMPK/mTOR pathway in HepG2 cells.

Bi-Jun Cheng, Jing Lu, Tian-Jiao Li, Zhuoqun Meng, Mei-Tong Liu, Mao-Cheng Sun, S. Guan

Food and Chemical Toxicology

DOI

2017

Protective effects of allicin on 1,3-DCP-induced lipid metabolism disorder in HepG2 cells.

Jing Lu, Bi-Jun Cheng, Baochen Fang, Zhuoqun Meng, Yiying Zheng, X. Tian, S. Guan

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

DOI

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精选作品

期刊论文

Sinensetin ameliorates established high-fat diet-induced liver injury and intestinal barrier dysfunction through the mitophagy/TLR4/MAPK signaling pathway

Mechanisms of apigenin in mitigating APAP-induced hepatocyte pyroptosis and liver injury via TRPV4 activation and ESCRT-mediated membrane repair

Protective effects of sinensetin on intestinal barrier damage induced by lipopolysaccharide in mice through TLR4/NLRP3/GSDMD pathway

Sinensetin Ameliorates Lipopolysaccharide-Induced Liver Injury by Targeting the TLR4/NF-κB/NLRP3 Pathway and Related Gut-Liver Axis Dysfunction in Mice.

Apigenin ameliorated ferroptosis induced by high-fat-diet via suppressing lysosome iron efflux in hepatocytes

Apigenin Reduces Lipid Droplet Accumulation in Hepatocytes by Enhancing Chaperone-Mediated Autophagy via AMPK.

Proanthocyanidins alleviate acute alcohol liver injury by inhibiting pyroptosis via inhibiting the ROS-MLKL-CTSB-NLRP3 pathway.

Ginsenoside Rb1 alleviates 3-MCPD-induced renal cell pyroptosis by activating mitophagy.

3-MCPD Induces Renal Cell Pyroptosis and Inflammation by Inhibiting ESCRT-III-Mediated Cell Repair and Mitophagy.

芹菜素激活自噬缓解高脂饮食所致肝损伤的作用机制研究

Apigenin Alleviated High-Fat-Diet-Induced Hepatic Pyroptosis by Mitophagy-ROS-CTSB-NLRP3 Pathway in Mice and AML12 Cells.

Ginsenoside Rb1 induces autophagic lipid degradation via miR-128 targeting TFEB.

1,3‐Dichloro‐2‐propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes

Apigenin alleviated PA-induced pyroptosis by activating autophagy in hepatocytes.

Apigenin induced autophagy and stimulated autophagic lipid degradation.

Apigenin reduces the excessive accumulation of lipids induced by palmitic acid via the AMPK signaling pathway in HepG2 cells

Alliin attenuates 1, 3‐dichloro‐2‐propanol‐induced lipogenesis in HepG2 cells through activation of the AMP‐activated protein kinase‐dependent pathway

1,3-Dichloro-2-Propanol inhibits autophagy via P53/AMPK/mTOR pathway in HepG2 cells.

Protective effects of allicin on 1,3-DCP-induced lipid metabolism disorder in HepG2 cells.

研究方向