谢子聪｜吉林大学｜学者主页

2026

PRMT3 restricts porcine epidemic diarrhea virus replication by disrupting the interaction between VAPA and the viral nucleocapsid protein

He-Yong Wu, Shu-Yu Zhong, Ao-Si Qi, Zi-Ru Wang, Qiu-Se Tu, Feng Li, Rui Wu, Jing-Yao Wang, Fan Song, Tian-Yi Zhang, Ting Li, Qing-Chun Yu, Hong-Ming Yuan, Dong-Mei Lv, Hong-Sheng Ouyang, Xi-Liang Du, Da-Xin Pang, Zicong Xie

PLoS Pathogens

DOI

2026

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, HongSheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie

Animal Research and One Health

DOI

2026

Immunogenicity assessment and epitope mapping of the ASFV proteome by profiling serum antibodies with ASFV antigen phage libraries

Lerong Ma, Zhen Weng, Yuanzhu Zhang, Zhi Cao, Xingjun Ke, Ruize Sun, Yin Xie, Mengjie Lian, Lin Yang, Hongming Yuan, Zicong Xie, HongSheng Ouyang, Daxin Pang, Dongmei Lv

Communications Biology

DOI

2024

Identification of porcine PARP11 as a restricted factor for pseudorabies virus

Chunyun Qi, Dehua Zhao, Xi Wang, Lanxin Hu, Yao Wang, Heyong Wu, Li Feng, Jian Zhou, Tianyi Zhang, Aosi Qi, Yuran Huo, Qiuse Tu, Shuyu Zhong, Hongming Yuan, Dongmei Lv, Shouqing Yan, Hongsheng Ouyang, Daxin Pang, Zicong Xie

Frontiers in Cellular and Infection Microbiology

DOI

2024

Accelerated discovery and miniaturization of novel single-stranded cytidine deaminases

Jiacheng Deng, Xueyuan Li, Hao Yu, Lin Yang, Ziru Wang, Wenfeng Yi, Ying Liu, Wenyu Xiao, Hongyong Xiang, Zicong Xie, Dongmei Lv, Hongsheng Ouyang, Daxin Pang, Hongming Yuan

Nucleic Acids Research

DOI

2024

Effective inhibition of PDCoV infection in chimeric APN gene-edited neonatal pigs

Jizong Li, Jian Zhao Zhou, Tianyi Zhang, Heyong Wu, Feng Li, Chunyun Qi, Liyuan Fan, Xuesong Yuan, Wei Wang, Rongli Guo, Baochao Fan, Xiaochun Tang, Daxin Pang, Hongsheng Ouyang, Zicong Xie, Bin Li

Journal of Virology

DOI

2024

Mechanism, structural and functional insights into nidovirus-induced double-membrane vesicles

Xi Wang, Yiwu Chen, Chunyun Qi, Feng Li, Yuanzhu Zhang, Jian Zhou, Heyong Wu, Tianyi Zhang, Aosi Qi, Hongsheng Ouyang, Zicong Xie, Daxin Pang

Frontiers in Immunology

DOI

2024

Regulatory Non-Coding RNAs during Porcine Viral Infections: Potential Targets for Antiviral Therapy

Feng Li, Hao Yu, Aosi Qi, Tianyi Zhang, Yuran Huo, Qiuse Tu, Chunyun Qi, Heyong Wu, Xi Wang, Jian Zhou, Lanxin Hu, Hongsheng Ouyang, Daxin Pang, Zicong Xie

Viruses

DOI

2022

Generation of APN-chimeric gene-edited pigs by CRISPR/Cas9-mediated knock-in strategy

Zhenying Liu, Mingjun Zhang, Peixuan Huang, Zhaoyang Ji, Chunyun Qi, Shuyu Jiao, Dehua Zhao, Yuan Jiang, Xue Chen, Dongmei Lv, Daxin Pang, Xin Zhang, Li Feng, Zicong Xie, Hongsheng Ouyang

Gene

DOI

2022

Generation of PCBP1-deficient pigs using CRISPR/Cas9-mediated gene editing

Chunyun Qi, Daxin Pang, Kang Yang, Shuyu Jiao, Heyong Wu, Chuheng Zhao, Lanxin Hu, Feng Li, Jian Zhou, Lin Yang, Dongmei Lv, Xiaochun Tang, Hongsheng Ouyang, Zicong Xie

iScience

DOI

2022

AbSE Workflow: Rapid Identification of the Coding Sequence and Linear Epitope of the Monoclonal Antibody at the Single-cell Level

Lerong Ma, Hongsheng Ouyang, Ang Su, Yuan‐Zhu Zhang, Daxin Pang, Tao Zhang, Ruize Sun, Wentao Wang, Zicong Xie, Dongmei Lv

ACS Synthetic Biology

DOI

2022

Identification and Functional Analysis of the Regulatory Elements in the pHSPA6 Promoter

Shuyu Jiao, Chunyan Bai, Chunyun Qi, Heyong Wu, Lanxin Hu, Feng Li, Kang Yang, Chuheng Zhao, Hongsheng Ouyang, Daxin Pang, Xiaochun Tang, Zicong Xie

Genes

DOI

2021

Generation and characterization of stable pig pregastrulation epiblast stem cell lines

Minglei Zhi, Jinying Zhang, Qianzi Tang, Dawei Yu, Shuai Gao, Dengfeng Gao, Pengliang Liu, Jianxiong Guo, Tang Hai, Jie Gao, Suying Cao, Zimo Zhao, Chongyang Li, Xiaogang Weng, Mengnan He, Tianzhi Chen, Yingjie Wang, Keren Long, Deling Jiao, Guanglei Li, Jiaman Zhang, Yan Liu, Yu Lin, Daxin Pang, Qianqian Zhu, Naixin Chen, Jingjing Huang, Xinze Chen, Yixuan Yao, Jingcang Yang, Zicong Xie, Xianya Huang, Mengxin Liu, Ran Zhang, Qiuyan Li, Yi‐Liang Miao, Jianhui Tian, Xingxu Huang, Hongsheng Ouyang, Bofeng Liu, Wei Xie, Qi Zhou, Hong‐Jiang Wei, Zhonghua Liu, Caihong Zheng, Mingzhou Li, Jianyong Han

Cell Research

DOI

2020

A CRISPR-engineered swine model of COL2A1 deficiency recapitulates altered early skeletal developmental defects in humans

Boyan Zhang, Chenyu Wang, Yue Zhang, Yuan Jiang, Yanguo Qin, Daxin Pang, Guizhen Zhang, He Liu, Zicong Xie, Hongming Yuan, Hongsheng Ouyang, Jincheng Wang, Xiaochun Tang

Bone

DOI

2020

Generation of a pHSPA6 gene-based multifunctional live cell sensor

Zicong Xie, Ruize Sun, Chunyun Qi, Shuyu Jiao, Yuan Jiang, Zhenying Liu, Dehua Zhao, Ruonan Liu, Qirong Li, Kang Yang, Lanxin Hu, Xinping Wang, Xiaochun Tang, Hongsheng Ouyang, Daxin Pang

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

DOI

2019

Generation of pRSAD2 gene knock-in pig via CRISPR/Cas9 technology

Zicong Xie, Huping Jiao, Haonan Xiao, Yuan Jiang, Zhenying Liu, Chunyun Qi, Dehua Zhao, Shuyu Jiao, Tingting Yu, Xiaochun Tang, Daxin Pang, Hongsheng Ouyang

Antiviral Research

DOI

2019

CRISPR/Cas9-Mediated Hitchhike Expression of Functional shRNAs at the Porcine miR-17-92 Cluster

Chao Lu, Daxin Pang, Mengjing Li, Hongming Yuan, Tingting Yu, Peixuan Huang, Jianing Li, Xue Chen, Huping Jiao, Zicong Xie, Hongsheng Ouyang

Cells

DOI

2018

基于CRISPR/Cas9的抗猪瘟病毒猪的制备

谢子聪

《吉林大学》

2018

Genetically modified pigs are protected from classical swine fever virus

Zicong Xie, Daxin Pang, Hongming Yuan, Huping Jiao, Chao Lu, Kankan Wang, Qiangbing Yang, Mengjing Li, Xue Chen, Tingting Yu, Xinrong Chen, Zhen Dai, Yani Peng, Xiaochun Tang, Zhanjun Li, Tiedong Wang, Huancheng Guo, Li Li, Changchun Tu, Liangxue Lai, Hongsheng Ouyang

PLoS Pathogens

DOI

2018

Site-Specific Fat-1 Knock-In Enables Significant Decrease of n-6PUFAs/n-3PUFAs Ratio in Pigs

Mengjing Li, Hongsheng Ouyang, Hongming Yuan, Jianing Li, Zicong Xie, Kankan Wang, Tingting Yu, Minghao Liu, Xue Chen, Xiaochun Tang, Huping Jiao, Daxin Pang

G3 Genes Genomes Genetics

DOI

2017

CRISPR/Cas9-mediated knockout of myostatin in Chinese indigenous Erhualian pigs

Kankan Wang, Xiaochun Tang, Zicong Xie, Xiaodong Zou, Mengjing Li, Hongming Yuan, Nannan Guo, Hongsheng Ouyang, Huping Jiao, Daxin Pang

Transgenic Research

DOI

2017

Optimization of a CRISPR/Cas9-mediated Knock-in Strategy at the Porcine Rosa26 Locus in Porcine Foetal Fibroblasts

Zicong Xie, Daxin Pang, Kankan Wang, Mengjing Li, Nannan Guo, Hongming Yuan, Jianing Li, Xiaodong Zou, Huping Jiao, Hongsheng Ouyang, Zhanjun Li, Xiaochun Tang

Scientific Reports

DOI

2017

Characterization and comparative analysis of immunoglobulin lambda chain diversity in a neonatal porcine model

Nannan Guo, Menghan Su, Zicong Xie, Kankan Wang, Hongming Yuan, Mengjing Li, Jianing Li, Minghao Liu, Jing Bai, Jing Liu, Hongsheng Ouyang, Daxin Pang, Huping Jiao

Veterinary Immunology and Immunopathology

DOI

2016

Efficient Generation of Orthologous Point Mutations in Pigs via CRISPR-assisted ssODN-mediated Homology-directed Repair

Kankan Wang, Xiaochun Tang, Yan Liu, Zicong Xie, Xiaodong Zou, Mengjing Li, Hongming Yuan, Hongsheng Ouyang, Huping Jiao, Daxin Pang

Molecular Therapy — Nucleic Acids

DOI

2015

Efficient Generation of Myostatin Mutations in Pigs Using the CRISPR/Cas9 System

Kankan Wang, Hongsheng Ouyang, Zicong Xie, Chaogang Yao, Nannan Guo, Mengjing Li, Huping Jiao, Daxin Pang

Scientific Reports

DOI

2014

Early lethality of shRNA-transgenic pigs due to saturation of microRNA pathways

Zhen Dai, Rong Wu, Yicheng Zhao, Kankan Wang, Yongye Huang, Xin Yang, Zicong Xie, Changchun Tu, Hongsheng Ouyang, Tiedong Wang, Daxin Pang

Journal of Zhejiang University SCIENCE B

DOI

谢子聪

精选作品

期刊论文

PRMT3 restricts porcine epidemic diarrhea virus replication by disrupting the interaction between VAPA and the viral nucleocapsid protein

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Immunogenicity assessment and epitope mapping of the ASFV proteome by profiling serum antibodies with ASFV antigen phage libraries

Identification of porcine PARP11 as a restricted factor for pseudorabies virus

Accelerated discovery and miniaturization of novel single-stranded cytidine deaminases

Effective inhibition of PDCoV infection in chimeric APN gene-edited neonatal pigs

Mechanism, structural and functional insights into nidovirus-induced double-membrane vesicles

Regulatory Non-Coding RNAs during Porcine Viral Infections: Potential Targets for Antiviral Therapy

Generation of APN-chimeric gene-edited pigs by CRISPR/Cas9-mediated knock-in strategy

Generation of PCBP1-deficient pigs using CRISPR/Cas9-mediated gene editing

AbSE Workflow: Rapid Identification of the Coding Sequence and Linear Epitope of the Monoclonal Antibody at the Single-cell Level

Identification and Functional Analysis of the Regulatory Elements in the pHSPA6 Promoter

Generation and characterization of stable pig pregastrulation epiblast stem cell lines

A CRISPR-engineered swine model of COL2A1 deficiency recapitulates altered early skeletal developmental defects in humans

Generation of a pHSPA6 gene-based multifunctional live cell sensor

Generation of pRSAD2 gene knock-in pig via CRISPR/Cas9 technology

CRISPR/Cas9-Mediated Hitchhike Expression of Functional shRNAs at the Porcine miR-17-92 Cluster

基于CRISPR/Cas9的抗猪瘟病毒猪的制备

Genetically modified pigs are protected from classical swine fever virus

Site-Specific Fat-1 Knock-In Enables Significant Decrease of n-6PUFAs/n-3PUFAs Ratio in Pigs

CRISPR/Cas9-mediated knockout of myostatin in Chinese indigenous Erhualian pigs

Optimization of a CRISPR/Cas9-mediated Knock-in Strategy at the Porcine Rosa26 Locus in Porcine Foetal Fibroblasts

Characterization and comparative analysis of immunoglobulin lambda chain diversity in a neonatal porcine model

Efficient Generation of Orthologous Point Mutations in Pigs via CRISPR-assisted ssODN-mediated Homology-directed Repair

Efficient Generation of Myostatin Mutations in Pigs Using the CRISPR/Cas9 System

Early lethality of shRNA-transgenic pigs due to saturation of microRNA pathways

会议论文

有效抑制PDCoV感染的APN嵌合基因编辑猪

预印本

PCBP1 Deficient Pigs Hold the Potential to Inhibit CSFV Infection

研究方向