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Shuai Fu, Ziheng An, Liangliang Wu, Zilei Xiang, Zixin Deng, Ran Liu, Tiangang Liu (2022). Evaluation and optimization of analytical procedure and sample preparation for polar Streptomyces albus J1074 metabolome profiling. Synthetic and Systems Biotechnology.DOI
Guoqing Zhai, Rong Gong, Yaxin Lin, Meng Zhang, Jiahui Li, Zixin Deng, Jia-Zhong Sun, Wenqing Chen, Zheng-Yu Zhang (2022). Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2′-Chloropentostatin Biosynthesis. ACS Catalysis.DOI
Tian Ma, Zixin Deng (2022). Reprograming yeast for anti-cancer vinblastine synthesis. Life Metabolism.DOI
Di Li, Ran Liu, Ming Wang, Rui Peng, Shuai Fu, Ai-Si Fu, Juan Le, Qian Yao, Teng-Fei Yuan, Hao-Ming Chi, Xin Mu, Ting Sun, Hang Liu, Pan Yan, Shao-Ting Wang, Sheng Cheng, Zixin Deng, Zhongchun Liu, Gaohua Wang, Yan Li, Tiangang Liu (2022). 3β-Hydroxysteroid dehydrogenase expressed by gut microbes degrades testosterone and is linked to depression in males. Cell Host and Microbe.DOI
Rong Chen, Tao Feng, Min Li, Xinyi Zhang, Juan He, Ben Hu, Zixin Deng, Tiangang Liu, Ji-Kai Liu, Xinghuan Wang, Guangkai Bian (2022). Characterization of Tremulane Sesquiterpene Synthase from the Basidiomycete Irpex lacteus. Organic Letters.DOI
Wei He, Haiyan Gao, Dan Wu, Su-Su Jiang, Wan-ling Huang, Chao Chen, Zixin Deng, Lei Xiong, Geng Wu, Lian-Rong Wang (2022). Structural and Functional Analysis of DndE Involved in DNA Phosphorothioation in the Haloalkaliphilic Archaea Natronorubrum bangense JCM10635. mBio.DOI
Yujie Yuan, Shu Cheng, Guangkai Bian, Pan Yan, Zhengning Ma, Wen Dai, Rong Chen, Shuai Fu, Huiwen Huang, Hao-Ming Chi, Yousheng Cai, Zixin Deng, Tiangang Liu (2022). Efficient exploration of terpenoid biosynthetic gene clusters in filamentous fungi. Nature Catalysis.DOI
Zi-Ling Ye, Bin-Hai Shi, Yanglei Huang, Tian Ma, Zilei Xiang, Ben Hu, Zhaolin Kuang, Man Huang, Xiaoying Lin, Z. Tian, Zixin Deng, Kun Shen, Tiangang Liu (2022). Revolution of vitamin E production by starting from microbial fermented farnesene to isophytol. The Innovation.DOI
Jin-Mei Zhu, Lu Yang, Jiequn Wu, Zixin Deng, X. Qu (2022). Engineering Imine Reductase for Efficient Biosynthesis of 1-Aryl-Tetrahydro-β-Carbolines and Their N-Methylation Products. ACS Catalysis.DOI
Mengmeng Zheng, Jun Zhang, Wan Zhang, Lu Yang, Xiaoli Yan, Wenya Tian, Zhihao Liu, Zhi Lin, Zixin Deng, Xudong Qu (2022). An Atypical Acyl‐CoA Synthetase Enables Efficient Biosynthesis of Extender Units for Engineering a Polyketide Carbon Scaffold. Angewandte Chemie.DOI
Kai Jiang, Xiaoli Yan, Zixin Deng, Chun Lei, Xudong Qu (2022). Expanding the Chemical Diversity of Fasamycin Via Genome Mining and Biocatalysis. Journal of Natural Products.DOI
Xiaoli Yan, Jun Zhang, Hongqun Tan, Zhihao Liu, Kai Jiang, Wenya Tian, Mengmeng Zheng, Zhi Lin, Zixin Deng, Xudong Qu (2022). A Pair of Atypical KAS III Homologues with Initiation and Elongation Functions Program the Polyketide Biosynthesis in Asukamycin. Angewandte Chemie.DOI
Zihua Zhou, Yang Xu, Tingting Huang, Jianting Zheng, Zixin Deng, Shaobo Dai, Shuangjun Lin (2022). Bifunctional NadC Homologue PyrZ Catalyzes Nicotinic Acid Formation in Pyridomycin Biosynthesis. ACS Chemical Biology.DOI
Yirong Xu, Liyun Ji, Shuo Xu, Muhammad Bilal, Armin Ehrenreich, Zixin Deng, Hairong Cheng (2022). Membrane-bound sorbitol dehydrogenase is responsible for the unique oxidation of D-galactitol to L-xylo-3-hexulose and D-tagatose in Gluconobacter oxydans. Biochimica et Biophysica Acta (BBA) - General Subjects.DOI
Song Xue, Jian Ma, Si‐Shang Li, Shuxuan Fan, YiChun Cai, Jiahao Li, Xiang Fu, Zixin Deng, Qiu Hong Sun, Yicheng Sun, Wei Ma (2022). Mining of the Novel Virulent ATP-Binding Cassette Importers in Mycobacterium abscessus by Comparative Genomic Strategy. Microbial Drug Resistance.DOI
Xiaozheng Wang, Dekun Kong, Tingting Huang, Fei Yun Xu, Man‐Cheng Tang, Zixin Deng, Shuangjun Lin (2022). Flavoprotein StnP2 Catalyzes the β-Carboline Formation during the Streptonigrin Biosynthesis. ACS Chemical Biology.DOI
Weiliang Xiong, Wanli Peng, Yali Fu, Zixin Deng, Shuangjun Lin, Rubing Liang (2022). Identification of a 17β-estradiol-degrading Microbacterium hominis SJTG1 with high adaptability and characterization of the genes for estrogen degradation. Journal of Hazardous Materials.DOI
Jianfeng Zhang, Jiahao Guan, Meng Wang, Gang Li, Marko Djordjević, Cui Tai, Hui Wang, Zixin Deng, Zhaoyan Chen, Hong‐Yu Ou (2022). SecReT6 update: a comprehensive resource of bacterial Type VI Secretion Systems. Science China Life Sciences.DOI
Dashan Zhang, Junbo Wang, Yongjian Qiao, Baixin Lin, Zixin Deng, Lingxin Kong, Delin You (2022). Genome Mining and Metabolic Profiling Reveal Cytotoxic Cyclodipeptides in Streptomyces hygrospinosus var. Beijingensis. Antibiotics.DOI
Yang Xu, Yiqun Wang, Guiyang Liu, Zixin Deng, Shuangjun Lin, Jianting Zheng (2022). Structural basis of Streptomyces transcription activation by zinc uptake regulator. Nucleic Acids Research.DOI
Jingwei Jia, Xiaozheng Wang, Jin Sang, Zhiyong Li, Shuangjun Lin, Zixin Deng, Tingting Huang (2022). An N-N linked dimeric indole alkaloid from the marine sponge-associated rare actinomycetes Kocuria sp. S42. Natural Product Research.DOI
Ying‐Xian Goh, Peifei Li, Meng Wang, Marko Djordjević, Cui Tai, Hui Wang, Zixin Deng, Zhaoyan Chen, Hong‐Yu Ou (2022). Comparative Analysis of Diverse Acetyltransferase-Type Toxin-Antitoxin Loci in Klebsiella pneumoniae. Microbiology Spectrum.DOI
Yuanyuan Feng, Yang Xu, Huining Ji, Zixin Deng, Shuangjun Lin, Jianting Zheng (2022). The Streptomyces viridochromogenes product template domain represents an evolutionary intermediate between dehydratase and aldol cyclase of type I polyketide synthases. Communications Biology.DOI
Yong Feng, Feng‐ling Zhang, Shuxin Huang, Zixin Deng, Linquan Bai, Jianting Zheng (2022). Structural visualization of transient interactions between the cis -acting acyltransferase and acyl carrier protein of the salinomycin modular polyketide synthase. Acta Crystallographica Section D Structural Biology.DOI
Xuyuan Wang, Mersa Darbandsari, Lixin Zhang, Zixin Deng (2022). Exploiting synthetic regulatory elements for non-dominant microorganisms. Synthetic and Systems Biotechnology.DOI
Meng Wang, Ying‐Xian Goh, Cui Tai, Hui Wang, Zixin Deng, Hong‐Yu Ou (2022). VRprofile2: detection of antibiotic resistance-associated mobilome in bacterial pathogens. Nucleic Acids Research.DOI
Qiang Huang, Ga Young Lee, Jiayi Li, Chuan Wang, Rosalinda L. Zhao, Zixin Deng, Kendall N. Houk, Yi‐Lei Zhao (2022). Origin of iodine preferential attack at sulfur in phosphorothioate and subsequent P-O or P-S bond dissociation. Proceedings of the National Academy of Sciences.DOI
Peng Li, Jinqi Zhang, Zixin Deng, Feng Gao, Hong‐Yu Ou (2022). Identification and characterization of a central replication origin of the mega-plasmid pSCATT of Streptomyces cattleya. Microbiological Research.DOI
Rubing Liang, Yali Fu, Wanli Peng, Shuangjun Lin, Zixin Deng (2022). The 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase HSD-X1 of Pseudomonas Citronellolis SJTE-3 Catalyzes the Conversion of 17β-estradiol to Estrone. Protein and Peptide Letters.DOI
Lingxin Kong, Zixin Deng, Delin You (2022). Chemistry and biosynthesis of bacterial polycyclic xanthone natural products. Natural Product Reports.DOI
Wanli Peng, Yanqiu Wang, Yali Fu, Zixin Deng, Shuangjun Lin, Rubing Liang (2022). Characterization of the Tellurite-Resistance Properties and Identification of the Core Function Genes for Tellurite Resistance in Pseudomonas citronellolis SJTE-3. Microorganisms.DOI
Jiayi Li, Haibo Wan, Haoqing Zhang, Xiaolei Wang, Guang Liu, Geng Wu, Xinyi He, Zixin Deng, Yi‐Lei Zhao (2022). Molecular recognition between bacterial phosphorothioate DNA and sulfur-binding domain (SBD): competition between the water cage and chalcogen-hydrophobic packet. Physical Chemistry Chemical Physics.DOI
Leixia Chu, Xiaoxia Luo, Taoting Zhu, Yingying Cao, Lili Zhang, Zixin Deng, Jiangtao Gao (2022). Harnessing phosphonate antibiotics argolaphos biosynthesis enables a synthetic biology-based green synthesis of glyphosate. Nature Communications.DOI
Jialiang Wang, Dandan Li, Lu Chen, Wei Cao, Liangliang Kong, Wei Zhang, Tristan Ian Croll, Zixin Deng, Jingdan Liang, Zhijun Wang (2022). Catalytic trajectory of a dimeric nonribosomal peptide synthetase subunit with an inserted epimerase domain. Nature Communications.DOI
Meng Zhang, Liyuan Kong, Rong Gong, Marianna Iorio, Stefano Donadio, Zixin Deng, Margherita Sosio, Wenqing Chen (2022). Biosynthesis of C-nucleoside antibiotics in actinobacteria: recent advances and future developments. Microbial Cell Factories.DOI
Xingzhi Jiao, Wei Huang, Anqi Wang, Banghao Wu, Qianjin Kang, Xiaoxia Luo, Linquan Bai, Zixin Deng (2022). Crystallographic Deciphering of Spontaneous Self‐Assembly of Achiral Calciphores to Chiral Complexes. Chemistry - A European Journal.DOI
Zixin Deng, Yi Qiang Yu (2022). Faculty Opinions recommendation of Evolution of increased complexity and specificity at the dawn of form I Rubiscos. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Yi Yu (2022). Faculty Opinions recommendation of Gene-Guided Discovery and Ribosomal Biosynthesis of Moroidin Peptides. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Man‐Cheng Tang, Cheng Xing Shen, Zixin Deng, Masao Ōhashi, Yi Tang (2022). Combinatorial Biosynthesis of Terpenoids through Mixing-and-Matching Sesquiterpene Cyclase and Cytochrome P450 Pairs. Organic Letters.DOI
Lu Zhu, Yang Song, Chenchen Chang, Hongmin Ma, Yang Lu, Zixin Deng, Wei Deng, Xudong Qu (2021). Engineering Leifsonia Alcohol Dehydrogenase for Thermostability and Catalytic Efficiency by Enhancing Subunit Interactions. ChemBioChem.DOI
Chenghai Sun, Haidong Peng, Wenlu Zhang, Mei Zheng, Wenya Tian, Yanan Zhang, Huanhuan Liu, Zhi Lin, Zixin Deng, Xudong Qu (2021). Production of Heterodimeric Diketopiperazines Employing a Mycobacterium-Based Whole-Cell Biocatalysis System. The Journal of Organic Chemistry.DOI
Qiang Huang, Ruohan Li, Tao Yi, Fengsong Cong, Dayong Wang, Zixin Deng, Yi‐Lei Zhao (2021). Author Correction: Phosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity. Communications Biology.DOI
Qiang Huang, Ruohan Li, Tao Yi, Fengsong Cong, Dayong Wang, Zixin Deng, Yi‐Lei Zhao (2021). Phosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity. Communications Biology.DOI
Yaojie Gao, Yuchun Zhao, Jie Zhou, Maohua Yang, Lin Lin, Wenning Wang, Meifeng Tao, Zixin Deng, Ming Sen Jiang (2021). Unexpected Role of a Short‐Chain Dehydrogenase/Reductase Family Protein in Type II Polyketide Biosynthesis. Angewandte Chemie.DOI
Dongjin Leng, Yong Hua Sheng, Hengyu Wang, Jianhua Wei, Yixin Ou, Zixin Deng, Linquan Bai, Qianjin Kang (2021). Determination of the Protein-Protein Interactions within Acyl Carrier Protein (MmcB)-Dependent Modifications in the Biosynthesis of Mitomycin. Molecules.DOI
Yumeng Zhang, Yangming Zhang, Yi Xiong, Hui Wang, Zixin Deng, Jiangning Song, Hong‐Yu Ou (2021). T4SEfinder: a bioinformatics tool for genome-scale prediction of bacterial type IV secreted effectors using pre-trained protein language model. Briefings in Bioinformatics.DOI
Wanli Peng, Yali Fu, Ben Jia, Xin Sun, Yanqiu Wang, Zixin Deng, Shuangjun Lin, Rubing Liang (2021). Metabolism analysis of 17α-ethynylestradiol by Pseudomonas citronellolis SJTE-3 and identification of the functional genes. Journal of Hazardous Materials.DOI
Wenyue Hu, Yuli Wang, Bingxu Yang, Lin Chen, Hao Yu, Guang Liu, Zixin Deng, Hong‐Yu Ou, Xinyi He (2021). Bacterial YedK represses plasmid DNA replication and transformation through its DNA single-strand binding activity. Microbiological Research.DOI
Kai Liu, Xin-Rui Hu, Li‐Xing Zhao, Yemin Wang, Zixin Deng, Meifeng Tao (2021). Enhancing Ristomycin A Production by Overexpression of ParB-Like StrR Family Regulators Controlling the Biosynthesis Genes. Applied and Environmental Microbiology.DOI
Xiankun Wang, Yuchun Zhao, Yaojie Gao, Xiangkun Luo, Aiqin Du, Zixin Deng, T. Mark Zabriskie, Xinyi He, Ming Sen Jiang (2021). A [3Fe-4S] cluster and tRNA-dependent aminoacyltransferase BlsK in the biosynthesis of Blasticidin S. Proceedings of the National Academy of Sciences.DOI
Suze Ma, Heng Chen, He Li, Xinjian Ji, Zixin Deng, Wei Ding, Qi Zhang (2021). Post‐Translational Formation of Aminomalonate by a Promiscuous Peptide‐Modifying Radical SAM Enzyme. Angewandte Chemie.DOI
Qi Liu, Xinyue Xie, Man‐Cheng Tang, Wentao Tao, Ting Shi, Yuanzhen Zhang, Tingting Huang, Yi‐Lei Zhao, Zixin Deng, Shuangjun Lin (2021). One-Pot Asymmetric Synthesis of an Aminodiol Intermediate of Florfenicol Using Engineered Transketolase and Transaminase. ACS Catalysis.DOI
Qing Wang, Lingxin Kong, Xiaoqing Zheng, Jufang Shen, Junbo Wang, Dashan Zhang, Yongjian Qiao, Jinjin Wang, Zixin Deng, Delin You (2021). Acyltransferase AniI, a Tailoring Enzyme with Broad Substrate Tolerance for High-Level Production of Anisomycin. Applied and Environmental Microbiology.DOI
Qian Liu, Xiang Guo, Guanhua Xun, Zhonglei Li, Yuesheng Chong, Litao Yang, Hongxia Wang, Fengchun Zhang, Shukun Luo, Li Cui, Pengshu Zhao, Xingyu Ye, Heshan Xu, Hui Juan Lu, Xiao Li, Zixin Deng, Kai Li, Yan Fang Feng (2021). Argonaute integrated single-tube PCR system enables supersensitive detection of rare mutations. Nucleic Acids Research.DOI
Yuli Wang, Wenyue Hu, Zixin Deng, Xinyi He (2021). Rapid identification of magnesium ascorbyl phosphate utilizing phosphatase through a chromogenic change-coupled activity assay. Applied Microbiology and Biotechnology.DOI
Xin Sun, Ruyan Li, Guochen Wan, Wanli Peng, Shuangjun Lin, Zixin Deng, Rubing Liang (2021). Spot 42 RNA regulates putrescine catabolism in Escherichia coli by controlling the expression of puuE at the post-transcription level. The Journal of Microbiology.DOI
Jinduo Cheng, Wenjuan Ji, Suze Ma, Xinjian Ji, Zixin Deng, Wei Ding, Qi Zhang (2021). Characterization and Mechanistic Study of the Radical SAM Enzyme ArsS Involved in Arsenosugar Biosynthesis. Angewandte Chemie.DOI
Huining Ji, Ting Shi, Lei Liu, Fa Zhang, Wentao Tao, Qing Min, Zixin Deng, Linquan Bai, Yi‐Lei Zhao, Jianting Zheng (2021). Computational studies on the substrate specificity of an acyltransferase domain from salinomycin polyketide synthase. Catalysis Science & Technology.DOI
Le Yu, Wenting Zhou, Yixuan She, Hongmin Ma, You‐Sheng Cai, Ming Sen Jiang, Zixin Deng, Neil P. J. Price, Wenqing Chen (2021). Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system. Nature Communications.DOI
Huahua Jian, Guanpeng Xu, Yi Yi, Yali Hao, Yinzhao Wang, Lei Xiong, Siyuan Wang, Shunzhang Liu, Canxing Meng, Jiahua Wang, Yue Zhang, Chao Chen, Xiaoyuan Feng, Haiwei Luo, Hao Zhang, Xingguo Zhang, Lianrong Wang, Zhijun Wang, Zixin Deng, Xiang Xiao (2021). The origin and impeded dissemination of the DNA phosphorothioation system in prokaryotes. Nature Communications.DOI
Xing Li, Xiaojing Hu, Yong Hua Sheng, Hengyu Wang, Meifeng Tao, Yixin Ou, Zixin Deng, Linquan Bai, Qianjin Kang (2021). Adaptive Optimization Boosted the Production of Moenomycin A in the Microbial Chassis Streptomyces albus J1074. ACS Synthetic Biology.DOI
Jialiang Wang, Jingdan Liang, Lu Chen, Wei Zhang, Liangliang Kong, Chao Peng, Chen Su, Yi Tang, Zixin Deng, Zhijun Wang (2021). Structural basis for the biosynthesis of lovastatin. Nature Communications.DOI
Yaojie Gao, Yuchun Zhao, Xinyi He, Zixin Deng, Ming Sen Jiang (2021). Challenges of functional expression of complex polyketide biosynthetic gene clusters. Current Opinion in Biotechnology.DOI
Sa Xiao, Zixin Deng, Jiangtao Gao (2021). CRISPR/Cas-based strategy for unearthing hidden chemical space from microbial genomes. Trends in Chemistry.DOI
Zixin Deng, Yi Qiang Yu (2021). Faculty Opinions recommendation of Bacterial endosymbionts protect beneficial soil fungus from nematode attack. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Richard H. Baltz, Erick J.M.C. Vandamme, Joan Wennstrom Bennett, Spiros Nicolas Agathos, Sergio Sánchez, Hiroyuki Osada, Zixin Deng, Ramón González (2021). Introduction and commentaries for the special issue: “Arnold L. Demain—A life lived”. Journal of Industrial Microbiology & Biotechnology.DOI
Zixin Deng, Yi Qiang Yu (2021). Faculty Opinions recommendation of Molecular insights into the endoperoxide formation by Fe(II)/α-KG-dependent oxygenase NvfI. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Haidong Peng, Yaya Wang, Kai Jiang, Xinru Chen, Wenlu Zhang, Yanan Zhang, Zixin Deng, Xudong Qu (2020). A Dual Role Reductase from Phytosterols Catabolism Enables the Efficient Production of Valuable Steroid Precursors. Angewandte Chemie.DOI
Xiaozheng Wang, Fei Yun Xu, Tingting Huang, Zixin Deng, Shuangjun Lin (2020). A novel streptonigrin type alkaloid from the Streptomyces flocculus CGMCC 4.1223 mutant ΔstnA/Q2. Natural Product Research.DOI
Sucheng Zhu, Tao Zheng, Lingxin Kong, Jinli Li, Bo Cao, Michael S. DeMott, Yihua Sun, Ying Chen, Zixin Deng, Peter C. Dedon, Delin You (2020). Development of Methods Derived from Iodine-Induced Specific Cleavage for Identification and Quantitation of DNA Phosphorothioate Modifications. Biomolecules.DOI
Kangmin Hua, Xiangyang Liu, Yuchun Zhao, Yaojie Gao, Lifeng Pan, Haoran Zhang, Zixin Deng, Ming Sen Jiang (2020). Offloading Role of a Discrete Thioesterase in Type II Polyketide Biosynthesis. mBio.DOI
Xiaojing Hu, Xing Li, Yong Hua Sheng, Hengyu Wang, Xiaobin Li, Yixin Ou, Zixin Deng, Linquan Bai, Qianjin Kang (2020). p-Aminophenylalanine Involved in the Biosynthesis of Antitumor Dnacin B1 for Quinone Moiety Formation. Molecules.DOI
Qiang Huang, Jiayi Li, Ting Shi, Jingdan Liang, Zhijun Wang, Linquan Bai, Zixin Deng, Yi‐Lei Zhao (2020). Defense Mechanism of Phosphorothioated DNA under Peroxynitrite-Mediated Oxidative Stress. ACS Chemical Biology.DOI
Xinqian Shen, Xiaozheng Wang, Tingting Huang, Zixin Deng, Shuangjun Lin (2020). Naphthoquinone-Based Meroterpenoids from Marine-Derived Streptomyces sp. B9173. Biomolecules.DOI
Yixin Ou, Yong Hua Sheng, Xiaojing Hu, Dongjin Leng, Jiafu Huang, Zhiyu Hu, Linquan Bai, Zixin Deng, Qianjin Kang, Ying‐Ying Wu (2020). Nonomuraea nitratireducens sp. nov., a new actinobacterium isolated from Suaeda australis Moq. rhizosphere. INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY.DOI
Yihua Sun, Lingxin Kong, Guojun Gary Wu, Bo Cao, Xiaoyan Pang, Zixin Deng, Peter C. Dedon, Chenhong Zhang, Delin You (2020). DNA Phosphorothioate Modifications Are Widely Distributed in the Human Microbiome. Biomolecules.DOI
Min Xu, Fei Zhang, Zhuo Cheng, Ghader Bashiri, Jing Wang, Jiali Hong, Yemin Wang, Lijun Xu, Xuefei Chen, Sheng‐Xiong Huang, Shuangjun Lin, Zixin Deng, Meifeng Tao (2020). Functional Genome Mining Reveals a Class V Lanthipeptide Containing a d ‐Amino Acid Introduced by an F420H2‐Dependent Reductase. Angewandte Chemie.DOI
Lingxin Kong, Qing Wang, Weinan Yang, Jufang Shen, Yan Li, Xiaoqing Zheng, Lu Wang, Yiwen Chu, Zixin Deng, Yit‐Heng Chooi, Delin You (2020). Three Recently Diverging Duplicated Methyltransferases Exhibit Substrate-Dependent Regioselectivity Essential for Xantholipin Biosynthesis. ACS Chemical Biology.DOI
Lingxin Kong, Qing Wang, Zixin Deng, Delin You (2020). Flavin Adenine Dinucleotide-Dependent Halogenase XanH and Engineering of Multifunctional Fusion Halogenases. Applied and Environmental Microbiology.DOI
Hao Yu, Jiayi Li, Guang Liu, Gong Zhao, Yuli Wang, Wenyue Hu, Zixin Deng, Geng Wu, Jianhua Gan, Yi‐Lei Zhao, Xinyi He (2020). DNA backbone interactions impact the sequence specificity of DNA sulfur-binding domains: revelations from structural analyses. Nucleic Acids Research.DOI
Chong Yin, Weiliang Xiong, Hua Qiu, Wanli Peng, Zixin Deng, Shuangjun Lin, Rubing Liang (2020). Characterization of the Phenanthrene-Degrading Sphingobium yanoikuyae SJTF8 in Heavy Metal Co-Existing Liquid Medium and Analysis of Its Metabolic Pathway. Microorganisms.DOI
Weinan Yang, Lingxin Kong, Qing Wang, Zixin Deng, Delin You (2020). Metabolic engineering of a methyltransferase for production of drug precursors demecycline and demeclocycline in Streptomyces aureofaciens. Synthetic and Systems Biotechnology.DOI
Fangting Wang, Wanqing Wei, Junfeng Zhao, Tianlu Mo, Xin Wang, Xuedong Huang, Suze Ma, Shu Wang, Zixin Deng, Wei Ding, Yong Fang Liang, Qi Zhang (2020). Genome Mining and Biosynthesis Study of a Type B Linaridin Reveals a Highly Versatile α- N -Methyltransferase. CCS Chemistry.DOI
Yaojun Tong, Zixin Deng (2020). An aurora of natural products-based drug discovery is coming. Synthetic and Systems Biotechnology.DOI
Liqiong Liu, Susu Jiang, Xing Mai, Chao Chen, Chongde Lai, Na Li, Guangfeng Liu, Dan Wu, Haiyan Gao, Liang Hong, Pan Tan, Shi Chen, Zixin Deng, Geng Wu, Lianrong Wang (2020). Structural Analysis of an l -Cysteine Desulfurase from an Ssp DNA Phosphorothioation System. mBio.DOI
Leixia Chu, Jinping Huang, Mustafa Muhammad, Zixin Deng, Jiangtao Gao (2020). Genome mining as a biotechnological tool for the discovery of novel marine natural products. Critical Reviews in Biotechnology.DOI
Xiaolin Xiong, Geng Wu, Yue Wei, Liqiong Liu, Yubing Zhang, Rui Su, Xianyue Jiang, Mengxue Li, Haiyan Gao, Xihao Tian, Yizhou Zhang, Li Hu, Si Chen, You Tang, Susu Jiang, Ruolin Huang, Zhiqiang Li, Yunfu Wang, Zixin Deng, Jiawei Wang, Peter C. Dedon, Shi Chen, Lianrong Wang (2020). SspABCD–SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities. Nature Microbiology.DOI
Wenjuan Ji, Xinjian Ji, Qi Zhang, Qi Zhang, Dhanaraju Mandalapu, Zixin Deng, Wei Ding, Peng Sun, Qi Zhang, Qi Zhang (2020). Sulfonium‐Based Homolytic Substitution Observed for the Radical SAM Enzyme HemN. Angewandte Chemie.DOI
Yong Hua Sheng, Yixin Ou, Xiaojing Hu, Zixin Deng, Linquan Bai, Qianjin Kang (2020). Generation of tetramycin B derivative with improved pharmacological property based on pathway engineering. Applied Microbiology and Biotechnology.DOI
Jin Lü, Qingshan Long, Zhilong Zhao, Lu Chen, Weijun He, Jiali Hong, Kai Liu, Yemin Wang, Xiuhua Pang, Zixin Deng, Meifeng Tao (2020). Engineering the Erythromycin-Producing Strain Saccharopolyspora erythraea HOE107 for the Heterologous Production of Polyketide Antibiotics. Frontiers in Microbiology.DOI
Rong Gong, Le Yu, Yini Qin, Neil P. J. Price, Xinyi He, Zixin Deng, Wenqing Chen (2020). Harnessing synthetic biology-based strategies for engineered biosynthesis of nucleoside natural products in actinobacteria. Biotechnology Advances.DOI
Chong Yin, Lin Chen, Hua Qiu, Weiliang Xiong, Shuangjun Lin, Zixin Deng, Man‐Cheng Tang, Rubing Liang (2020). Production of high-value drug precursors by the whole-cell catalyst based on the transformation of ring-hydroxylating dioxygenase to aromatic compounds. Bioresource Technology Reports.DOI
Qinqin Zhao, Yuchang Luo, Xin Zhang, Qianjin Kang, Dan Zhang, Lili Zhang, Linquan Bai, Zixin Deng (2020). A severe leakage of intermediates to shunt products in acarbose biosynthesis. Nature Communications.DOI
Chenghai Sun, Zhenyao Luo, Wenlu Zhang, Wenya Tian, Haidong Peng, Zhi Lin, Zixin Deng, Boštjan Kobe, Xinying Jia, Xudong Qu (2020). Molecular basis of regio- and stereo-specificity in biosynthesis of bacterial heterodimeric diketopiperazines. Nature Communications.DOI
Zixin Deng, Xudong Qu (2020). Faculty Opinions recommendation of Directed evolution of a halide methyltransferase enables biocatalytic synthesis of diverse SAM analogs. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Xudong Qu (2020). Faculty Opinions recommendation of Quinolactacin Biosynthesis Involves Non-Ribosomal-Peptide-Synthetase-Catalyzed Dieckmann Condensation to Form the Quinolone-γ-lactam Hybrid. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Xudong Qu (2020). Faculty Opinions recommendation of Investigation of indigoidine synthetase reveals conserved active site base residue of nonribosomal peptide synthetase oxidases. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Xuan Yun, Qian Zhang, Meinan Lv, H. Deng, Zixin Deng, Yi Yu (2019). In vitro reconstitution of the biosynthetic pathway of 3-hydroxypicolinic acid. Organic and biomolecular chemistry.DOI
Ran Liu, Fang Fang, Ziheng An, Renqiong Huang, Yong Wang, Xiao Ling Sun, Shuai Fu, Aisi Fu, Zixin Deng, Tiangang Liu (2019). Genomics-driven discovery of the biosynthetic gene cluster of maduramicin and its overproduction in Actinomadura sp. J1-007. Journal of Industrial Microbiology & Biotechnology.DOI
Lu Yang, Jinmei Zhu, Chenghai Sun, Zixin Deng, Xudong Qu (2019). Biosynthesis of plant tetrahydroisoquinoline alkaloids through an imine reductase route. Chemical Science.DOI
Yawei Zhao, Jinzhong Tian, Guosong Zheng, Jun Chen, Chuanwen Sun, Zhongyi Yang, Andrei Antonovich Zimin, Weihong Jiang, Zixin Deng, Zhijun Wang, Yinhua Lü (2019). Multiplex genome editing using a dCas9-cytidine deaminase fusion in Streptomyces. Science China Life Sciences.DOI
Weiliang Xiong, Chong Yin, Wanli Peng, Zixin Deng, Shuangjun Lin, Rubing Liang (2019). Characterization of an 17β-estradiol-degrading bacterium Stenotrophomonas maltophilia SJTL3 tolerant to adverse environmental factors. Applied Microbiology and Biotechnology.DOI
Xiangyang Liu, Kangmin Hua, Dongxu Liu, Zhen‐Long Wu, Ying Wang, Haoran Zhang, Zixin Deng, Blaine A. Pfeifer, Ming Sen Jiang (2019). Heterologous Biosynthesis of Type II Polyketide Products Using E. coli. ACS Chemical Biology.DOI
Lingxin Kong, Jia Liu, Xiaoqing Zheng, Zixin Deng, Delin You (2019). CtcS, a MarR family regulator, regulates chlortetracycline biosynthesis. BMC Microbiology.DOI
Fa Zhang, Huining Ji, Imtiaz Ali, Zixin Deng, Linquan Bai, Jianting Zheng (2019). Structural and Biochemical Insight into the Recruitment of Acyl Carrier Protein‐Linked Extender Units in Ansamitocin Biosynthesis. ChemBioChem.DOI
Tianning Pu, Zhiling Mei, Wei Zhang, Weijun Liang, Xiufen Zhou, Jingdan Liang, Zixin Deng, Zhijun Wang (2019). An in vitro DNA phosphorothioate modification reaction. Molecular Microbiology.DOI
Qingshan Long, Daniel E. Jeffries, Shuangjun Lin, Xuefei Chen, Weijun He, Yemin Wang, Zixin Deng, Craig W. Lindsley, Meifeng Tao (2019). RedH and PigC Catalyze the Biosynthesis of Hybrubins via Phosphorylation of 4′-Methoxy-2,2′-Bipyrrole-5′-Carbaldehyde. Applied and Environmental Microbiology.DOI
Weiliang Xiong, Chong Yin, Yanqiu Wang, Shuangjun Lin, Zixin Deng, Rubing Liang (2019). Characterization of an efficient estrogen-degrading bacterium Stenotrophomonas maltophilia SJTH1 in saline-, alkaline-, heavy metal-contained environments or solid soil and identification of four 17β-estradiol-oxidizing dehydrogenases. Journal of Hazardous Materials.DOI
Tianlu Mo, Xinjian Ji, Wei Yuan, Dhanaraju Mandalapu, Fangting Wang, Yuting Zhong, Fuyou Li, Qin kai Chen, Wei Ding, Zixin Deng, Shaoning Yu, Qi Zhang (2019). Thuricin Z: A Narrow‐Spectrum Sactibiotic that Targets the Cell Membrane. Angewandte Chemie.DOI
Qian Liu, Wenjie Fan, Yajin Zhao, Zixin Deng, Yan Fang Feng (2019). Probing and Engineering the Fatty Acyl Substrate Selectivity of Starter Condensation Domains of Nonribosomal Peptide Synthetases in Lipopeptide Biosynthesis. Biotechnology Journal.DOI
Hongliang Qian, Hao Yu, Peifei Li, Eric Zhu, Qingqing Yao, Cui Tai, Zixin Deng, Kenn Gerdes, Xinyi He, Jianhua Gan, Hong‐Yu Ou (2019). Toxin–antitoxin operon kacAT of Klebsiella pneumoniae is regulated by conditional cooperativity via a W-shaped KacA–KacT complex. Nucleic Acids Research.DOI
Fa Zhang, Ting Shi, Huining Ji, Imtiaz Ali, Shuxin Huang, Zixin Deng, Qing Min, Linquan Bai, Yi‐Lei Zhao, Jianting Zheng (2019). Structural Insights into the Substrate Specificity of Acyltransferases from Salinomycin Polyketide Synthase. Biochemistry.DOI
Jinli Li, Yi Chen, Tao Zheng, Lingxin Kong, Sucheng Zhu, Yihua Sun, Zixin Deng, Litao Yang, Delin You (2019). Quantitative mapping of DNA phosphorothioatome reveals phosphorothioate heterogeneity of low modification frequency. PLoS Genetics.DOI
Xinjian Ji, Tianlu Mo, Wan‐Qiu Liu, Wei Ding, Zixin Deng, Qi Zhang (2019). Revisiting the Mechanism of the Anaerobic Coproporphyrinogen III Oxidase HemN. Angewandte Chemie.DOI
Tianning Pu, Jingdan Liang, Zhiling Mei, Yan Yang, Jialiang Wang, Wei Zhang, Weijun Liang, Xiufen Zhou, Zixin Deng, Zhijun Wang (2019). Phosphorothioated DNA Is Shielded from Oxidative Damage. Applied and Environmental Microbiology.DOI
Zhong Xu, Yuanyuan Li, Yemin Wang, Zixin Deng, Meifeng Tao (2019). Genome-Wide Mutagenesis Links Multiple Metabolic Pathways with Actinorhodin Production in Streptomyces coelicolor. Applied and Environmental Microbiology.DOI
Jufang Shen, Lingxin Kong, Yán Li, Xiaoqing Zheng, Qing Wang, Weinan Yang, Zixin Deng, Delin You (2019). A LuxR family transcriptional regulator AniF promotes the production of anisomycin and its derivatives in Streptomyces hygrospinosus var. beijingensis. Synthetic and Systems Biotechnology.DOI
Yingying Cao, Qingyao Peng, Shanni Li, Zixin Deng, Jiangtao Gao (2019). The intriguing biology and chemistry of fosfomycin: the only marketed phosphonate antibiotic. RSC Advances.DOI
Yi Chen, Tao Zheng, Jinli Li, Jinjie Cui, Zixin Deng, Delin You, Litao Yang (2019). Novel Iodine-induced Cleavage Real-time PCR Assay for Accurate Quantification of Phosphorothioate Modified Sites in Bacterial DNA. Scientific Reports.DOI
Wei Kang, Tian Ma, Min Liu, Jiale Qu, Zhenjun Liu, Huawei Zhang, Bin Shi, Shuai Fu, Juncai Ma, Louis Tung Faat Lai, Sicong He, Jianan Y. Qu, Shannon Wing‐Ngor Au, Byung‐Ho Kang, Wilson Chun Yu Lau, Zixin Deng, Jiang Xia, Tiangang Liu (2019). Modular enzyme assembly for enhanced cascade biocatalysis and metabolic flux. Nature Communications.DOI
Zixin Deng, Xudong Qu (2019). Faculty Opinions recommendation of A marine viral halogenase that iodinates diverse substrates. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Xiaojie Wang, Zixin Deng, Tiangang Liu (2019). Marker‐Free System Using Ribosomal Promoters Enhanced Xylose/Glucose Isomerase Production in Streptomyces rubiginosus. Biotechnology Journal.DOI
Zixin Deng, Xudong Qu (2019). Faculty Opinions recommendation of A Biocatalytic Platform for Synthesis of Chiral α-Trifluoromethylated Organoborons. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Yuhui Sun (2019). Faculty Opinions recommendation of MZH29 is a novel potent inhibitor that overcomes drug resistance FLT3 mutations in acute myeloid leukemia. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Yuhui Sun (2019). Faculty Opinions recommendation of Complete reconstitution of the diverse pathways of gentamicin B biosynthesis. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Li Chen, Nathchar Naowarojna, Bin Chen, Meiling Xu, Melissa Quill, Jiangyun Wang, Zixin Deng, Changming Zhao, Ping-Hua Liu (2018). Mechanistic Studies of a Nonheme Iron Enzyme OvoA in Ovothiol Biosynthesis Using a Tyrosine Analogue, 2-Amino-3-(4-hydroxy-3-(methoxyl) phenyl) Propanoic Acid (MeOTyr). ACS Catalysis.DOI
Yan Li, Lingxin Kong, Jufang Shen, Qing Wang, Qian Liu, Weinan Yang, Zixin Deng, Delin You (2018). Characterization of the positive SARP family regulator PieR for improving piericidin A1 production in Streptomyces piomogeues var. Hangzhouwanensis. Synthetic and Systems Biotechnology.DOI
Meng Liu, Xiaobin Li, Yingzhou Xie, Dexi Bi, Jingyong Sun, Jun Li, Cui Tai, Zixin Deng, Hong‐Yu Ou (2018). ICEberg 2.0: an updated database of bacterial integrative and conjugative elements. Nucleic Acids Research.DOI
Zixin Deng, Yi Yu (2018). Faculty Opinions recommendation of A molecular mechanism for the enzymatic methylation of nitrogen atoms within peptide bonds. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Gudan Xu, Liyuan Kong, Rong Gong, Liudong Xu, Yaojie Gao, Ming Sen Jiang, You‐Sheng Cai, Kui Hong, Youcai Hu, Peng Liu, Zixin Deng, Neil P. J. Price, Wenqing Chen (2018). Coordinated Biosynthesis of the Purine Nucleoside Antibiotics Aristeromycin and Coformycin in Actinomycetes. Applied and Environmental Microbiology.DOI
Hao Yu, Guang Liu, Gong Zhao, Wenyue Hu, Geng Wu, Zixin Deng, Xinyi He (2018). Identification of a conserved DNA sulfur recognition domain by characterizing the phosphorothioate‐specific endonuclease SprMcrA from Streptomyces pristinaespiralis. Molecular Microbiology.DOI
Tingting Huang, Yingyi Duan, Yi Zou, Zixin Deng, Shuangjun Lin (2018). NRPS Protein MarQ Catalyzes Flexible Adenylation and Specific S-Methylation. ACS Chemical Biology.DOI
Hui Tao, Yuchen Zhang, Zixin Deng, Tiangang Liu (2018). Strategies for Enhancing the Yield of the Potent Insecticide Spinosad in Actinomycetes. Biotechnology Journal.DOI
Liqiong Liu, Yizhou Zhang, Dongxu Jiang, Shiming Du, Zixin Deng, Lianrong Wang, Shi Chen (2018). Recent Advances in the Genomic Profiling of Bacterial Epigenetic Modifications. Biotechnology Journal.DOI
Shuangju Wu, Lianrong Wang, Rui Gan, Tong Tong, Hao Bian, Zhiqiang Li, Shiming Du, Zixin Deng, Shi Chen (2018). Signature Arsenic Detoxification Pathways in Halomonas sp. Strain GFAJ-1. mBio.DOI
Xiaobin Li, Yingzhou Xie, Meng Liu, Cui Tai, Jingyong Sun, Zixin Deng, Hong‐Yu Ou (2018). oriTfinder: a web-based tool for the identification of origin of transfers in DNA sequences of bacterial mobile genetic elements. Nucleic Acids Research.DOI
Rong Gong, Jianzhao Qi, Pan Wu, You‐Sheng Cai, Hongmin Ma, Yang Liu, He Duan, Meng Wang, Zixin Deng, Neil P. J. Price, Wenqing Chen (2018). An ATP-Dependent Ligase with Substrate Flexibility Involved in Assembly of the Peptidyl Nucleoside Antibiotic Polyoxin. Applied and Environmental Microbiology.DOI
Yingzhou Xie, Lijun Tian, Gang Li, Hongping Qu, Jingyong Sun, Wei Liang, Xiaobin Li, Wang Xiaoli, Zixin Deng, Jialin Liu, Hong‐Yu Ou (2018). Emergence of the third-generation cephalosporin-resistant hypervirulent Klebsiella pneumoniae due to the acquisition of a self-transferable blaDHA-1-carrying plasmid by an ST23 strain. Virulence.DOI
Xuefei Chen, Min Xu, Jin Lü, Jianguo Xu, Yemin Wang, Shuangjun Lin, Zixin Deng, Meifeng Tao (2018). Biosynthesis of Tropolones in Streptomyces spp.: Interweaving Biosynthesis and Degradation of Phenylacetic Acid and Hydroxylations on the Tropone Ring. Applied and Environmental Microbiology.DOI
Hao Wu, Jingdan Liang, Jialiang Wang, Weijun Liang, Lixia Gou, Qiulin Wu, Xiufen Zhou, Ian James Bruce, Zixin Deng, Zhijun Wang (2018). Cezomycin Is Activated by CalC to Its Ester Form for Further Biosynthesis Steps in the Production of Calcimycin in Streptomyces chartreusis NRRL 3882. Applied and Environmental Microbiology.DOI
Hao Wu, Jingdan Liang, Lixia Gou, Qiulin Wu, Weijun Liang, Xiufen Zhou, Ian James Bruce, Zixin Deng, Zhijun Wang (2018). Recycling of Overactivated Acyls by a Type II Thioesterase during Calcimycin Biosynthesis in Streptomyces chartreusis NRRL 3882. Applied and Environmental Microbiology.DOI
Qinying Peng, Guixi Gao, Jin Lü, Qingshan Long, Xuefei Chen, Fei Zhang, Min Xu, Kai Liu, Yemin Wang, Zixin Deng, Zhiyong Li, Meifeng Tao (2018). Engineered Streptomyces lividans Strains for Optimal Identification and Expression of Cryptic Biosynthetic Gene Clusters. Frontiers in Microbiology.DOI
Guang Liu, Wencheng Fu, Zhenyi Zhang, Yao He, Hao Yu, Yuli Wang, Xiaolei Wang, Yi‐Lei Zhao, Zixin Deng, Geng Wu, Xinyi He (2018). Structural basis for the recognition of sulfur in phosphorothioated DNA. Nature Communications.DOI
Jinqi Zhang, Xiaobin Li, Zixin Deng, Hong‐Yu Ou (2018). Comparative Analysis of CRISPR Loci Found in Streptomyces Genome Sequences. Interdisciplinary Sciences Computational Life Sciences.DOI
Tian Ma, Bin Shi, Ziling Ye, Xiaowei Li, Min Liu, Yun Chen, Jiang Xia, JENS KVIST NIELSEN, Zixin Deng, Tiangang Liu (2018). Lipid engineering combined with systematic metabolic engineering of Saccharomyces cerevisiae for high-yield production of lycopene. Metabolic Engineering.DOI
Ran Liu, Zixin Deng, Tiangang Liu (2018). Streptomyces species: Ideal chassis for natural product discovery and overproduction. Metabolic Engineering.DOI
Chen‐Guang Liu, Meijuan Yuan, Xu Xu, Lei Wang, Adrian T. Keatinge‐Clay, Zixin Deng, Shuangjun Lin, Jianting Zheng (2018). Substrate-bound structures of a ketoreductase from amphotericin modular polyketide synthase. Journal of Structural Biology.DOI
Si-Sun Choi, Yohei Katsuyama, Linquan Bai, Zixin Deng, Yasuo Ohnishi, Eung‐Soo Kim (2018). Genome engineering for microbial natural product discovery. Current Opinion in Microbiology.DOI
Hongliang Qian, Qingqing Yao, Cui Tai, Zixin Deng, Jianhua Gan, Hong‐Yu Ou (2018). Identification and characterization of acetyltransferase‐type toxin‐antitoxin locus in Klebsiella pneumoniae. Molecular Microbiology.DOI
Luyun Zhang, Junjie Ji, Meijuan Yuan, Yuanyuan Feng, Lei Wang, Zixin Deng, Linquan Bai, Jianting Zheng (2018). Stereospecificity of Enoylreductase Domains from Modular Polyketide Synthases. ACS Chemical Biology.DOI
Zixin Deng, Xudong Qu (2018). Faculty Opinions recommendation of Adenylation activity of carboxylic acid reductases enables the synthesis of amides. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Sicong Li, Junhong Guo, Anna Reva, Fanglu Huang, Bin‐Bin Xiong, Yuanzhen Liu, Zixin Deng, Peter F. Leadlay, Yuhui Sun (2018). Methyltransferases of gentamicin biosynthesis. Proceedings of the National Academy of Sciences.DOI
Xiangyang Liu, Dongxu Liu, Min Xu, Meifeng Tao, Linquan Bai, Zixin Deng, Blaine A. Pfeifer, Ming Sen Jiang (2018). Reconstitution of Kinamycin Biosynthesis within the Heterologous Host Streptomyces albus J1074. Journal of Natural Products.DOI
Xiaozheng Wang, Dekun Kong, Tingting Huang, Zixin Deng, Shuangjun Lin (2018). StnK2 catalysing a Pictet–Spengler reaction involved in the biosynthesis of the antitumor reagent streptonigrin. Organic & Biomolecular Chemistry.DOI
Yingyi Duan, Yanyan Liu, Tao Huang, Yi Zou, Tingting Huang, Kaifeng Hu, Zixin Deng, Shuangjun Lin (2018). Divergent biosynthesis of indole alkaloids FR900452 and spiro-maremycins. Organic & Biomolecular Chemistry.DOI
Zixin Deng, Xudong Qu (2018). Faculty Opinions recommendation of In vitro biosynthesis of the nonproteinogenic amino acid methoxyvinylglycine. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Xudong Qu (2018). Faculty Opinions recommendation of Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Xudong Qu (2018). Faculty Opinions recommendation of Isonitrile Formation by a Non-Heme Iron(II)-Dependent Oxidase/Decarboxylase. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Xudong Qu (2018). Faculty Opinions recommendation of Asymmetric reductive carbocyclization using engineered ene reductases. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Xiankun Wang, Aiqin Du, Guiyang Yu, Zixin Deng, Xinyi He (2017). Guanidine N-methylation by BlsL Is Dependent on Acylation of Beta-amine Arginine in the Biosynthesis of Blasticidin S. Frontiers in Microbiology.DOI
Yan Yang, Guanpeng Xu, Jingdan Liang, Ying He, Lei Xiong, Hui Li, Douglas Hoyt Bartlett, Zixin Deng, Zhijun Wang, Xiang Xiao (2017). DNA Backbone Sulfur-Modification Expands Microbial Growth Range under Multiple Stresses by its anti-oxidation function. Scientific Reports.DOI
Yu Zhuang, Guangyu Yang, Xiaohui Chen, Qian Liu, Xueli Zhang, Zixin Deng, Yan Fang Feng (2017). Biosynthesis of plant-derived ginsenoside Rh2 in yeast via repurposing a key promiscuous microbial enzyme. Metabolic Engineering.DOI
Gao‐Yi Tan, Kunhua Deng, Xinhua Liu, Hui Tao, Yingying Chang, Jia Chen, Kai Chen, Zhi Sheng, Zixin Deng, Tiangang Liu (2017). Heterologous Biosynthesis of Spinosad: An Omics-Guided Large Polyketide Synthase Gene Cluster Reconstitution in Streptomyces. ACS Synthetic Biology.DOI
Siqi Wang, Hengwei Wang, Jiyang Lv, Zixin Deng, Hairong Cheng (2017). Highly Efficient Erythritol Recovery from Waste Erythritol Mother Liquor by a Yeast-Mediated Biorefinery Process. Journal of Agricultural and Food Chemistry.DOI
Yingzhou Xie, Yiqing Wei, Yue Liang Shen, Xiaobin Li, Hao Zhou, Cui Tai, Zixin Deng, Hong‐Yu Ou (2017). TADB 2.0: an updated database of bacterial type II toxin–antitoxin loci. Nucleic Acids Research.DOI
Lu Liu, Meiping Ye, Xiaobin Li, Jun Li, Zixin Deng, Yufeng Yao, Hong‐Yu Ou (2017). Identification and Characterization of an Antibacterial Type VI Secretion System in the Carbapenem-Resistant Strain Klebsiella pneumoniae HS11286. Frontiers in Cellular and Infection Microbiology.DOI
Yuanzhen Liu, Xu Chen, Zhengyuan Li, Wei Xu, Weixin Tao, Jie Wu, Jian Yang, Zixin Deng, Yuhui Sun (2017). Functional Analysis of Cytochrome P450s Involved in Streptovaricin Biosynthesis and Generation of Anti-MRSA Analogues. ACS Chemical Biology.DOI
Yuyang Zhang, Yi Zou, Nelson L. Brock, Tingting Huang, Yingxia Lan, Xiaozheng Wang, Zixin Deng, Yi Tang, Shuangjun Lin (2017). Characterization of 2-Oxindole Forming Heme Enzyme MarE, Expanding the Functional Diversity of the Tryptophan Dioxygenase Superfamily. Journal of the American Chemical Society.DOI
Guixi Gao, Xiangyang Liu, Min Xu, Yemin Wang, Fei Zhang, Lijun Xu, Jin Xiong Lv, Qingshan Long, Qianjin Kang, Hong‐Yu Ou, Ying Wang, Jürgen Rohr, Zixin Deng, Ming Sen Jiang, Shuangjun Lin, Meifeng Tao (2017). Formation of an Angular Aromatic Polyketide from a Linear Anthrene Precursor via Oxidative Rearrangement. Cell chemical biology.DOI
Xiaoqing Zheng, Qiuxiang Cheng, Fen Yao, Xiaozheng Wang, Lingxin Kong, Bo Cao, Min Xu, Shuangjun Lin, Zixin Deng, Yit‐Heng Chooi, Delin You (2017). Biosynthesis of the pyrrolidine protein synthesis inhibitor anisomycin involves novel gene ensemble and cryptic biosynthetic steps. Proceedings of the National Academy of Sciences.DOI
Lijuan Li, Hengwei Wang, Hairong Cheng, Zixin Deng (2017). Isomaltulose production by yeast surface display of sucrose isomerase from Pantoea dispersa on Yarrowia lipolytica. Journal of Functional Foods.DOI
Zhong Xu, Yemin Wang, Keith Frederick Chater, Hong‐Yu Ou, H. Howard Xu, Zixin Deng, Meifeng Tao (2017). Large-Scale Transposition Mutagenesis of Streptomyces coelicolor Identifies Hundreds of Genes Influencing Antibiotic Biosynthesis. Applied and Environmental Microbiology.DOI
Zixin Deng, Yi Qiang Yu (2017). Faculty Opinions recommendation of Natural products discovery from micro-organisms in the post-genome era. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Yi Yu (2017). Faculty Opinions recommendation of Enabling techniques in the search for new antibiotics: Combinatorial biosynthesis of sugar-containing antibiotics. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Yi Qiang Yu (2017). Faculty Opinions recommendation of C3'-Deoxygenation of Paromamine Catalyzed by a Radical S-Adenosylmethionine Enzyme: Characterization of the Enzyme AprD4 and Its Reductase Partner AprD3. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Yi Qiang Yu (2017). Faculty Opinions recommendation of Aminoglycoside Antibiotics: New Insights into the Biosynthetic Machinery of Old Drugs. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Yi Qiang Yu (2017). Faculty Opinions recommendation of Mechanisms of resistance to aminoglycoside antibiotics: overview and perspectives. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Yi Qiang Yu (2017). Faculty Opinions recommendation of Substrate specificity of radical S-adenosyl-l-methionine dehydratase AprD4 and its partner reductase AprD3 in the C3'-deoxygenation of aminoglycoside antibiotics. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Yi Qiang Yu (2017). Faculty Opinions recommendation of New trends in aminoglycosides use. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Yi Qiang Yu (2017). Faculty Opinions recommendation of Ribosome-targeting antibiotics and mechanisms of bacterial resistance. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Yi Qiang Yu (2017). Faculty Opinions recommendation of Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Yi Yu (2017). Faculty Opinions recommendation of Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Qing-yi Xie, Jian Ren, Lei Li, Yu. V. Li, Zixin Deng, K. Hong (2016). Micromonospora mangrovi sp. nov., isolated from mangrove soil. Antonie van Leeuwenhoek.DOI
K. Hong, R. Yin, Hang-Zhen Chai, Zhitong Dong, Zixin Deng (2016). Diterpene compound variediene synthesizing gene Au13192 and application thereof.
Nisha He, Pan Wu, Yong-Xing Lei, Baofu Xu, Xiao-Cheng Zhu, Gudan Xu, Yao-Jie Gao, Jian-Zhao Qi, Zixin Deng, G. Tang, Wenqing Chen, Youli Xiao (2016). Construction of an octosyl acid backbone catalyzed by a radical S-adenosylmethionine enzyme and a phosphatase in the biosynthesis of high-carbon sugar nucleoside antibiotics. Chemical Science.DOI
Qian Liu, Liping Xiao, Yuanjie Zhou, Kunhua Deng, Gao‐Yi Tan, Yichao Han, Xinhua Liu, Zixin Deng, Tiangang Liu (2016). Development of Streptomyces sp. FR-008 as an emerging chassis. Synthetic and Systems Biotechnology.DOI
Gong Zhao, Chen Cheng, Wei Xiong, Tuling Gao, Zixin Deng, Geng Wu, Xinyi He (2016). Structural basis of the substrate preference towards CMP for a thymidylate synthase MilA involved in mildiomycin biosynthesis. Scientific Reports.DOI
Yemin Wang, Zhengsheng Tao, Hualiang Zheng, Fei Zhang, Qingshan Long, Zixin Deng, Meifeng Tao (2016). Iteratively improving natamycin production in Streptomyces gilvosporeus by a large operon-reporter based strategy. Metabolic Engineering.DOI
Houyuan Zhao, Liang Wang, Dan Wan, Jianzhao Qi, Rong Gong, Zixin Deng, Wenqing Chen (2016). Characterization of the aurantimycin biosynthetic gene cluster and enhancing its production by manipulating two pathway-specific activators in Streptomyces aurantiacus JA 4570. Microbial Cell Factories.DOI
Daofeng Dai, Aiqin Du, Kangli Xiong, Tianning Pu, Xiufen Zhou, Zixin Deng, Jingdan Liang, Xinyi He, Zhijun Wang (2016). DNA Phosphorothioate Modification Plays a Role in Peroxides Resistance in Streptomyces lividans. Frontiers in Microbiology.DOI
Peng Li, Cui Tai, Zixin Deng, Jianhua Gan, Marco Rinaldo Oggioni, Hong‐Yu Ou (2016). Identification and characterization of chromosomal relBE toxin-antitoxin locus in Streptomyces cattleya DSM46488. Scientific Reports.DOI
Hengwei Wang, Lijuan Li, Lebin Zhang, Jin Hee An, Hairong Cheng, Zixin Deng (2016). Xylitol production from waste xylose mother liquor containing miscellaneous sugars and inhibitors: one-pot biotransformation by Candida tropicalis and recombinant Bacillus subtilis. Microbial Cell Factories.DOI
Dekun Kong, Yi Zou, Zhang Zhang, Fei Yun Xu, Nelson L. Brock, Liping Zhang, Zixin Deng, Shuangjun Lin (2016). Identification of (2S,3S)-β-Methyltryptophan as the Real Biosynthetic Intermediate of Antitumor Agent Streptonigrin. Scientific Reports.DOI
Jun Li, Cui Tai, Zixin Deng, Weihong Zhong, Yongqun Oliver He, Hong‐Yu Ou (2016). VRprofile: gene-cluster-detection-based profiling of virulence and antibiotic resistance traits encoded within genome sequences of pathogenic bacteria. Briefings in Bioinformatics.DOI
Ning Li, Hengwei Wang, Lijuan Li, Huiling Cheng, Huiling Cheng, Dawen Liu, Hairong Cheng, Hairong Cheng, Zixin Deng (2016). Integrated Approach To Producing High-Purity Trehalose from Maltose by the Yeast Yarrowia lipolytica Displaying Trehalose Synthase (TreS) on the Cell Surface. Journal of Agricultural and Food Chemistry.DOI
Min Xu, Yemin Wang, Zhilong Zhao, Guixi Gao, Sheng‐Xiong Huang, Qianjin Kang, Xinyi He, Shuangjun Lin, Xiuhua Pang, Zixin Deng, Meifeng Tao (2016). Functional Genome Mining for Metabolites Encoded by Large Gene Clusters through Heterologous Expression of a Whole-Genome Bacterial Artificial Chromosome Library in Streptomyces spp. Applied and Environmental Microbiology.DOI
Wenqing Chen, Yan Li, Jie Li, Lian Wu, Yan Li, Renxiao Wang, Zixin Deng, Jiahai Zhou (2016). An unusual UMP C-5 methylase in nucleoside antibiotic polyoxin biosynthesis. Protein & Cell.DOI
Yingxia Lan, Yi Zou, Tingting Huang, Xiaozheng Wang, Nelson L. Brock, Zixin Deng, Shuangjun Lin (2016). Indole methylation protects diketopiperazine configuration in the maremycin biosynthetic pathway. Science China Chemistry.DOI
Sifan Wu, Tingting Huang, Dan Xie, Jing Wo, Xiaozheng Wang, Zixin Deng, Shuangjun Lin (2016). Xantholipin B produced by the stnR inactivation mutant Streptomyces flocculus CGMCC 4.1223 WJN-1. The Journal of Antibiotics.DOI
Ziling Ye, Xiaowei Li, Yongbo Cheng, Zhijie Liu, Gao‐Yi Tan, Fayin Zhu, Shuai Fu, Zixin Deng, Tiangang Liu (2016). Evaluation of 3-hydroxypropionate biosynthesis in vitro by partial introduction of the 3-hydroxypropionate/4-hydroxybutyrate cycle fromMetallosphaera sedula. Journal of Industrial Microbiology & Biotechnology.DOI
Tingting Huang, Lili Li, Nelson L. Brock, Zixin Deng, Shuangjun Lin (2016). Functional Characterization of PyrG, an Unusual Nonribosomal Peptide Synthetase Module from the Pyridomycin Biosynthetic Pathway. ChemBioChem.DOI
Lebin Zhang, Jin Hee An, Lijuan Li, Hengwei Wang, Dawen Liu, Ning Li, Hairong Cheng, Zixin Deng (2016). Highly Efficient Fructooligosaccharides Production by an Erythritol-Producing Yeast Yarrowia lipolytica Displaying Fructosyltransferase. Journal of Agricultural and Food Chemistry.DOI
Jin Hee An, Lebin Zhang, Lijuan Li, Dawen Liu, Huiling Cheng, Huiling Cheng, Hengwei Wang, Muhammad Zohaib Nawaz, Hairong Cheng, Hairong Cheng, Zixin Deng (2016). An Alternative Approach to Synthesizing Galactooligosaccharides by Cell-Surface Display of β-Galactosidase on Yarrowia lipolytica. Journal of Agricultural and Food Chemistry.DOI
Lingxin Kong, Weike Zhang, Yit‐Heng Chooi, Lu Wang, Bo Cao, Zixin Deng, Yiwen Chu, Delin You (2016). A Multifunctional Monooxygenase XanO4 Catalyzes Xanthone Formation in Xantholipin Biosynthesis via a Cryptic Demethoxylation. Cell chemical biology.DOI
Jing Wo, Dekun Kong, Nelson L. Brock, Fei Yun Xu, Xiufen Zhou, Zixin Deng, Shuangjun Lin (2016). Transformation of Streptonigrin to Streptonigrone: Flavin Reductase-Mediated Flavin-Catalyzed Concomitant Oxidative Decarboxylation of Picolinic Acid Derivatives. ACS Catalysis.DOI
Hui Tao, Yuchen Zhang, Xiaoying Cao, Zixin Deng, Tiangang Liu (2016). Absolute quantification of proteins in the fatty acid biosynthetic pathway using protein standard absolute quantification. Synthetic and Systems Biotechnology.DOI
Dexi Bi, Yingzhou Xie, Cui Tai, Xiaofei Jiang, Jie Zhang, Ewan M. Harrison, Shiru Jia, Zixin Deng, Kumar Rajakumar, Hong‐Yu Ou (2016). A Site-Specific Integrative Plasmid Found in Pseudomonas aeruginosa Clinical Isolate HS87 along with A Plasmid Carrying an Aminoglycoside-Resistant Gene. PLoS ONE.DOI
Zhilong Zhao, Ting Shi, Min Xu, Nelson L. Brock, Yi‐Lei Zhao, Yemin Wang, Zixin Deng, Xiuhua Pang, Meifeng Tao (2016). Hybrubins: Bipyrrole Tetramic Acids Obtained by Crosstalk between a Truncated Undecylprodigiosin Pathway and Heterologous Tetramic Acid Biosynthetic Genes. Organic Letters.DOI
Zixin Deng, Yuhui Sun (2016). Faculty Opinions recommendation of CasHRA (Cas9-facilitated Homologous Recombination Assembly) method of constructing megabase-sized DNA. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Yuhui Sun (2016). Faculty Opinions recommendation of Cytochrome P450-catalyzed regio- and stereoselective phenol coupling of fungal natural products. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Yuhui Sun (2016). Faculty Opinions recommendation of Identification of the key enzyme of roseoflavin biosynthesis. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
H. Zeng, Shishi Wen, Wei Xu, Zhaoren He, Guifa Zhai, Yunkun Liu, Zixin Deng, Yu-Hui Sun (2015). Highly efficient editing of the actinorhodin polyketide chain length factor gene in Streptomyces coelicolor M145 using CRISPR/Cas9-CodA(sm) combined system. Applied Microbiology and Biotechnology.DOI
Dong Xu, Min Ma, Zixin Deng, K. Hong (2015). Genotype-driven isolation of enterocin with novel bioactivities from mangrove-derived Streptomyces qinglanensis 172205. Applied Microbiology and Biotechnology.DOI
Guiyang Yu, Li Li, Xiangyang Liu, Guang Liu, Zixin Deng, Mark Zabriskie, Ming Sen Jiang, Xinyi He (2015). The standalone aminopeptidase PepN catalyzes the maturation of blasticidin S from leucylblasticidin S. Scientific Reports.DOI
Yunkun Liu, Weixin Tao, Shishi Wen, Zhengyuan Li, Anna Yang, Zixin Deng, Yuhui Sun (2015). In Vitro CRISPR/Cas9 System for Efficient Targeted DNA Editing. mBio.DOI
Li Cui, Ying Zhu, Xiao‐Qing Guan, Zixin Deng, Linquan Bai, Yan Fang Feng (2015). De Novo Biosynthesis of β-Valienamine in Engineered Streptomyces hygroscopicus 5008. ACS Synthetic Biology.DOI
Jianzhao Qi, Jin Liu, Dan Wan, You‐Sheng Cai, Yinghu Wang, Shunying Li, Pan Wu, Xuan Feng, Guofu Qiu, Sheng‐ping Yang, Wenqing Chen, Zixin Deng (2015). Metabolic engineering of an industrial polyoxin producer for the targeted overproduction of designer nucleoside antibiotics. Biotechnology and Bioengineering.DOI
Hong‐Yu Ou, Shan N. Kuang, Xinyi He, Brenda M. Molgora, Peter J. Ewing, Zixin Deng, Melanie Osby, Wangxue Chen, H. Howard Xu (2015). Complete genome sequence of hypervirulent and outbreak-associated Acinetobacter baumannii strain LAC-4: epidemiology, resistance genetic determinants and potential virulence factors. Scientific Reports.DOI
Peipei Zhang, Zhilong Zhao, Zixin Deng, Xiuhua Pang, Xiu‐Lan Chen, Linquan Bai, Hao Li (2015). Production of the antibiotic FR-008/candicidin in Streptomyces sp. FR-008 is co-regulated by two regulators, FscRI and FscRIV, from different transcription factor families. Microbiology.DOI
Mo Han, Haixing Yin, Yi Zou, Nelson L. Brock, Tingting Huang, Zixin Deng, Yiwen Chu, Shuangjun Lin (2015). An Acyl Transfer Reaction Catalyzed by an Epimerase MarH. ACS Catalysis.DOI
Chenchen Zhu, Qianjin Kang, Linquan Bai, Lin Cheng, Zixin Deng (2015). Identification and engineering of regulation-related genes toward improved kasugamycin production. Applied Microbiology and Biotechnology.DOI
Dexi Bi, Xiaofei Jiang, Zi-Ke Sheng, David Ngmenterebo, Cui Tai, Minggui Wang, Zixin Deng, Kumar Rajakumar, Hong‐Yu Ou (2015). Mapping the resistance-associated mobilome of a carbapenem-resistantKlebsiella pneumoniaestrain reveals insights into factors shaping these regions and facilitates generation of a ‘resistance-disarmed’ model organism. Journal of Antimicrobial Chemotherapy.DOI
Wenqing Chen, Jianzhao Qi, Pan Wu, Dan Wan, Jin Yi Liu, Xuan Feng, Zixin Deng (2015). Natural and engineered biosynthesis of nucleoside antibiotics in Actinomycetes. Journal of Industrial Microbiology & Biotechnology.DOI
Hui Tao, Daoyi Guo, Yuchen Zhang, Zixin Deng, Tiangang Liu (2015). Metabolic engineering of microbes for branched-chain biodiesel production with low-temperature property. Biotechnology for Biofuels.DOI
Qiuxiang Cheng, Bo Cao, Fen Yao, Jinli Li, Zixin Deng, Delin You (2015). Regulation of DNA phosphorothioate modifications by the transcriptional regulator DptB in Salmonella. Molecular Microbiology.DOI
Fuhou Li, Jingdan Liang, Weixia Wang, Xiufen Zhou, Zixin Deng, Zhijun Wang (2015). Two nucleoside receptors from Streptomyces coelicolor: Expression of the genes and characterization of the recombinant proteins. Protein Expression and Purification.DOI
Jun Li, Yufeng Yao, H. Howard Xu, Limin Hao, Zixin Deng, Kumar Rajakumar, Hong‐Yu Ou (2015). SecReT6 : a web‐based resource for type VI secretion systems found in bacteria. Environmental Microbiology.DOI
Tiesheng Han, Megumu Yamada-Mabuchi, Gong Zhao, Li Li, Guang Liu, Hong‐Yu Ou, Zixin Deng, Yu Zheng, Xinyi He (2015). Recognition and cleavage of 5-methylcytosine DNA by bacterial SRA-HNH proteins. Nucleic Acids Research.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of Structure of a modular polyketide synthase. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of The structure of docking domains in modular polyketide synthases. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of Structural rearrangements of a polyketide synthase module during its catalytic cycle. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of A biosynthetic pathway for BE-7585A, a 2-thiosugar-containing angucycline-type natural product. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of Complete biosynthesis of opioids in yeast. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of A microbial biomanufacturing platform for natural and semisynthetic opioids. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: versatility from a unique substrate channel. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of Molecular cloning, expression, and characterization of amorpha-4,11-diene synthase, a key enzyme of artemisinin biosynthesis in Artemisia annua L. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of Terminal alkene formation by the thioesterase of curacin A biosynthesis: structure of a decarboxylating thioesterase. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of A tylosin ketoreductase reveals how chirality is determined in polyketides. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of An enzyme-coupled biosensor enables (S)-reticuline production in yeast from glucose. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of Divergence of multimodular polyketide synthases revealed by a didomain structure. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of High-level semi-synthetic production of the potent antimalarial artemisinin. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of Structural and functional analysis of C2-type ketoreductases from modular polyketide synthases. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of Engineering a mevalonate pathway in Escherichia coli for production of terpenoids. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of Structural and stereochemical analysis of a modular polyketide synthase ketoreductase domain required for the generation of a cis-alkene. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of Stereochemical inversion of (S)-reticuline by a cytochrome P450 fusion in opium poppy. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of Plant science. Morphinan biosynthesis in opium poppy requires a P450-oxidoreductase fusion protein. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2015). Faculty Opinions recommendation of Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Xudong Qu (2015). Faculty Opinions recommendation of Vinylation of unprotected phenols using a biocatalytic system. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Yuhui Sun (2015). Faculty Opinions recommendation of A new antibiotic kills pathogens without detectable resistance. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Yuhui Sun (2015). Faculty Opinions recommendation of Biosynthesis of versipelostatin: identification of an enzyme-catalyzed [4+2]-cycloaddition required for macrocyclization of spirotetronate-containing polyketides. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
R. Gan, Xiao-Lin Wu, Wei He, Zhenhua Liu, Shuangju Wu, Chao Chen, Si Chen, Qianrong Xiang, Zixin Deng, Dequan Liang, Shi Chen, Lian-Rong Wang (2014). DNA phosphorothioate modifications influence the global transcriptional response and protect DNA from double-stranded breaks. Scientific Reports.DOI
Yan-Ling Ma, Wei Xu, Jun Zhang, Sihong Zhang, K. Hong, Zixin Deng, Yu-Hui Sun (2014). Nitrilase superfamily aryl acylamidase from the halotolerant mangrove Streptomyces sp. 211726. Applied Microbiology and Biotechnology.DOI
Peipei Zhang, Hang Wu, Xiu‐Lan Chen, Zixin Deng, Linquan Bai, Xiuhua Pang (2014). Regulation of the biosynthesis of thiopeptide antibiotic cyclothiazomycin by the transcriptional regulator SHJG8833 in Streptomyces hygroscopicus 5008. Microbiology.DOI
Zixin Deng, Yuhui Sun (2014). Faculty Opinions recommendation of Improving CRISPR-Cas nuclease specificity using truncated guide RNAs. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Liu Guang, Zhenyi Zhang, Gong Zhao, Zixin Deng, Geng Wu, Xinyi He (2014). Crystallization and preliminary X-ray analysis of the type IV restriction endonuclease ScoMcrA fromStreptomyces coelicolor, which cleaves both Dcm-methylated DNA and phosphorothioated DNA. Acta Crystallographica Section F Structural Biology Communications.DOI
Xiaoli Zhou, Le Gao, Guangyu Yang, Donglai Liu, Aixi Bai, Bin-Chun Li, Zixin Deng, Yan Fang Feng (2014). Design of Hyperthermophilic Lipase Chimeras by Key Motif‐Directed Recombination. ChemBioChem.DOI
Limeng Chen, Xiaolei Wang, Ting Shi, Tingting Wu, Zixin Deng, Yi‐Lei Zhao (2014). Theoretical Study on the Relationship between Rp-Phosphorothioation and Base-Step in S-DNA: Based on Energetic and Structural Analysis. The Journal of Physical Chemistry B.DOI
Hengwei Wang, Feng‐Qing Wang, Wei Wang, Yao Xueling, Dongzhi Wei, Hairong Cheng, Zixin Deng (2014). Improving the Expression of Recombinant Proteins in E. coli BL21 (DE3) under Acetate Stress: An Alkaline pH Shift Approach. PLoS ONE.DOI
Fuhou Li, Jingdan Liang, Weixia Wang, Xiufen Zhou, Zixin Deng, Zhijun Wang (2014). Analysis of Streptomyces coelicolor membrane proteome using two-dimensional native/native and native/sodium dodecyl sulfate gel electrophoresis. Analytical Biochemistry.DOI
Bo Cao, Qiuxiang Cheng, Chen Gu, Fen Yao, Michael S. DeMott, Xiaoqing Zheng, Zixin Deng, Peter C. Dedon, Delin You (2014). Pathological phenotypes and in vivo DNA cleavage by unrestrained activity of a phosphorothioate‐based restriction system in S almonella. Molecular Microbiology.DOI
Dandan Sun, Wei Yan Sun, Yinxian Yu, Zhiyong Li, Zixin Deng, Shuangjun Lin (2014). A new glutarimide derivative from marine sponge-derived Streptomyces anulatus S71. Natural Product Research.DOI
Gong Zhao, Geng Wu, Yan Zhang, Guang Liu, Tiesheng Han, Zixin Deng, Xinyi He (2014). Structure of theN-glycosidase MilB in complex with hydroxymethyl CMP reveals its Arg23 specifically recognizes the substrate and controls its entry. Nucleic Acids Research.DOI
Jun Li Feng, Jun Wu, Jie Gao, Zhigui Xia, Zixin Deng, Xinyi He (2014). Biosynthesis of the β-Methylarginine Residue of Peptidyl Nucleoside Arginomycin in Streptomyces arginensis NRRL 15941. Applied and Environmental Microbiology.DOI
Yanhua Du, Yemin Wang, Tingting Huang, Meifeng Tao, Zixin Deng, Shuangjun Lin (2014). Identification and characterization of the biosynthetic gene cluster of polyoxypeptin A, a potent apoptosis inducer. BMC Microbiology.DOI
Hairong Cheng, Jiyang Lv, Hengwei Wang, Ben Wang, Zilong Li, Zixin Deng (2014). Genetically engineered Pichia pastoris yeast for conversion of glucose to xylitol by a single-fermentation process. Applied Microbiology and Biotechnology.DOI
Chen Zhang, Lingxin Kong, Lei Xuan, Zixin Deng, Delin You (2014). Advance in the Research on Quinomycins Biosynthesis. Chinese Journal of Organic Chemistry.DOI
Tingli Bai, Daozhong Zhang, Shuangjun Lin, Qingshan Long, Yemin Wang, Hong‐Yu Ou, Qianjin Kang, Zixin Deng, Wen Liu, Meifeng Tao (2014). Operon for Biosynthesis of Lipstatin, the Beta-Lactone Inhibitor of Human Pancreatic Lipase. Applied and Environmental Microbiology.DOI
Zixin Deng, Yuhui Sun (2014). Faculty Opinions recommendation of An engineered pathway for the biosynthesis of renewable propane. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Xudong Qu (2014). Faculty Opinions recommendation of A methyltransferase initiates terpene cyclization in teleocidin B biosynthesis. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Xudong Qu (2014). Faculty Opinions recommendation of SpyTag/SpyCatcher cyclization confers resilience to boiling on a mesophilic enzyme. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Tiangang Liu (2014). Faculty Opinions recommendation of Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid-derived biofuels and chemicals. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Wenqing Chen, Daofeng Dai, Changchun Wang, Tingting Huang, Lipeng Zhai, Zixin Deng (2013). Genetic dissection of the polyoxin building block-carbamoylpolyoxamic acid biosynthesis revealing the “pathway redundancy” in metabolic networks. Microbial Cell Factories.DOI
Tao Zhu, Xueqing Cheng, Yuntian Liu, Zixin Deng, Delin You (2013). Deciphering and engineering of the final step halogenase for improved chlortetracycline biosynthesis in industrial Streptomyces aureofaciens. Metabolic Engineering.DOI
Cheng Chen, TuLing Gao, Gong Zhao, Zixin Deng, Shen-Cai Hu, H. Howard Xu, Xinyi He (2013). Evidence from 18O feeding studies for hydroxyl group donor in the reaction catalyzed by cytidylate hydroxymethylase MilA. Chinese Science Bulletin.DOI
Bo Cao, Chao Chen, Michael S. DeMott, Qiuxiang Cheng, Tyson A. Clark, Xiaolin Xiong, Xiaoqing Zheng, Vincent L. Butty, Stuart S. Levine, George Yuan, Matthew Boitano, Khai Luong, Yi Song, Xiufen Zhou, Zixin Deng, Stephen W. Turner, Jonas Korlach, Delin You, Lianrong Wang, Shi Chen, Peter C. Dedon (2013). Genomic mapping of phosphorothioates reveals partial modification of short consensus sequences. RePEc: Research Papers in Economics.
Yi Zou, Qi Fang, Haixing Yin, Zutao Liang, Dekun Kong, Linquan Bai, Zixin Deng, Shuangjun Lin (2013). Stereospecific Biosynthesis of β‐Methyltryptophan from L ‐Tryptophan Features a Stereochemical Switch. Angewandte Chemie.DOI
Dongmei Xu, Liu Guang, Lin Cheng, Xinhua Lu, Wenqing Chen, Zixin Deng (2013). Identification of Mur34 as the Novel Negative Regulator Responsible for the Biosynthesis of Muraymycin in Streptomyces sp. NRRL30471. PLoS ONE.DOI
Xianhui An, Xiufen Zhou, Zhijun Wang, Zixin Deng, Jingdan Liang (2013). [Cloning, expression and purification of dptC, a DNA phosphorothioate modification related gene from Salmonella enteric serovar Cerro 87]. PubMed.
Jun Li Feng, Jun Wu, Nan Dai, Shuangjun Lin, H. Howard Xu, Zixin Deng, Xinyi He (2013). Discovery and Characterization of BlsE, a Radical S-Adenosyl-L-methionine Decarboxylase Involved in the Blasticidin S Biosynthetic Pathway. PLoS ONE.DOI
WenQin Pan, Qianjin Kang, Lei Wang, Linquan Bai, Zixin Deng (2013). Asm8, a specific LAL-type activator of 3-amino-5-hydroxybenzoate biosynthesis in ansamitocin production. Science China Life Sciences.DOI
Lixia Gou, Qiulin Wu, Shuangjun Lin, Xiangmei Li, Jingdan Liang, Xiufen Zhou, Derong An, Zixin Deng, Zhijun Wang (2013). Mutasynthesis of pyrrole spiroketal compound using calcimycin 3-hydroxy anthranilic acid biosynthetic mutant. Applied Microbiology and Biotechnology.DOI
Qiulin Wu, Lixia Gou, Shuangjun Lin, Jingdan Liang, Jun Yin, Xiufen Zhou, Linquan Bai, Derong An, Zixin Deng, Zhijun Wang (2013). Characterization of the N-methyltransferase CalM involved in calcimycin biosynthesis by Streptomyces chartreusis NRRL 3882. Biochimie.DOI
Yi Zou, Haixing Yin, Dekun Kong, Zixin Deng, Shuangjun Lin (2013). A Trans‐Acting Ketoreductase in Biosynthesis of a Symmetric Polyketide Dimer SIA7248. ChemBioChem.DOI
Chen Zhang, Lingxin Kong, Qian Liu, Lei Xuan, Tao Zhu, Jun Yin, Birun Lin, Zixin Deng, Delin You (2013). In Vitro Characterization of Echinomycin Biosynthesis: Formation and Hydroxylation of L-Tryptophanyl-S-Enzyme and Oxidation of (2S,3S) β-Hydroxytryptophan. PLoS ONE.DOI
Li Li, Jun Wu, Zixin Deng, T. Mark Zabriskie, Xinyi He (2013). Streptomyces lividans Blasticidin S Deaminase and Its Application in Engineering a Blasticidin S-Producing Strain for Ease of Genetic Manipulation. Applied and Environmental Microbiology.DOI
Fei Yun Xu, Dekun Kong, Xinyi He, Zhang Zhang, Mo Han, Xinqiang Xie, Peng Wang, Hairong Cheng, Meifeng Tao, Liping Zhang, Zixin Deng, Shuangjun Lin (2013). Characterization of Streptonigrin Biosynthesis Reveals a Cryptic Carboxyl Methylation and an Unusual Oxidative Cleavage of a N–C Bond. Journal of the American Chemical Society.DOI
Zixin Deng, Xudong Qu (2013). Faculty Opinions recommendation of Unusual acetylation-dependent reaction cascade in the biosynthesis of the pyrroloindole drug physostigmine. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Zixin Deng, Xudong Qu (2013). Faculty Opinions recommendation of Expanding the fluorine chemistry of living systems using engineered polyketide synthase pathways. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.DOI
Qing-yi Xie, Hai-peng Lin, Lei Li, Ros Brown, M. Goodfellow, Zixin Deng, K. Hong (2012). Verrucosispora wenchangensis sp. nov., isolated from mangrove soil. Antonie van Leeuwenhoek.DOI
Jing Li, Xudong Qu, Xinyi He, Lian Duan, Guojun Gary Wu, Dexi Bi, Zixin Deng, Wen Liu, Hong‐Yu Ou (2012). ThioFinder: A Web-Based Tool for the Identification of Thiopeptide Gene Clusters in DNA Sequences. PLoS ONE.DOI
Wei Hu, Chengkun Wang, Jingdan Liang, Tianlong Zhang, Zhongpei Hu, Zhijun Wang, Wenxian Lan, Fang Li, Houming Wu, Jianping Ding, Geng Wu, Zixin Deng, Chunyang Cao (2012). Structural insights into DndE from Escherichia coli B7A involved in DNA phosphorothioation modification. Cell Research.DOI
Lipeng Zhai, Shuangjun Lin, Dongjing Qu, Xuechuan Hong, Linquan Bai, Wenqing Chen, Zixin Deng (2012). Engineering of an industrial polyoxin producer for the rational production of hybrid peptidyl nucleoside antibiotics. Metabolic Engineering.DOI
Lei Xuan, Lingxin Kong, Chen Zhang, Qian Liu, Fen Yao, Weike Zhang, Zixin Deng, Delin You (2012). In vivo investigation of the substrate recognition capability and activity affecting amino acid residues of glycosyltransferase FscMI in the biosynthesis of candicidin. Molecular BioSystems.DOI
Xianhui An, Wei Xiong, Yan Yang, Fuhou Li, Xiufen Zhou, Zhijun Wang, Zixin Deng, Jingdan Liang (2012). A Novel Target of IscS in Escherichia coli: Participating in DNA Phosphorothioation. PLoS ONE.DOI
Bo Cao, Fen Yao, Xiaoqing Zheng, Dongbing Cui, Yucheng Shao, Changxiong Zhu, Zixin Deng, Delin You (2012). Genome Mining of the Biosynthetic Gene Cluster of the Polyene Macrolide Antibiotic Tetramycin and Characterization of a P450 Monooxygenase Involved in the Hydroxylation of the Tetramycin B Polyol Segment. ChemBioChem.DOI
Michael J. Smanski, Xudong Qu, Wen Liu, Ben Shen, Yi Tang, Yi Yu, Zixin Deng (2012). Biosynthesis of Pharmaceutical Natural Products and Their Pathway Engineering.DOI
Yichao Zhang, Juan Liang, Peng Lian, Yiwen Han, Yifan Chen, Linquan Bai, Zhijun Wang, Jingdan Liang, Zixin Deng, Yi‐Lei Zhao (2012). Theoretical Study on Steric Effects of DNA Phosphorothioation: B-Helical Destabilization in Rp-Phosphorothioated DNA. The Journal of Physical Chemistry B.DOI
Hang Wu, Shuang Qu, Chenyang Lu, Huajun Zheng, Xiufen Zhou, Linquan Bai, Zixin Deng (2012). Genomic and transcriptomic insights into the thermo-regulated biosynthesis of validamycin in Streptomyces hygroscopicus 5008. BMC Genomics.DOI
Chunhua Zhao, Peng Li, Zixin Deng, Hong‐Yu Ou, Ryan P. McGlinchey, David O’Hagan (2012). Insights into fluorometabolite biosynthesis in Streptomyces cattleya DSM46488 through genome sequence and knockout mutants. Bioorganic Chemistry.DOI
Xinqiang Xie, Jingdan Liang, Tianning Pu, Fei Xu, Fen Yao, Yan Yang, Yi‐Lei Zhao, Delin You, Xiufen Zhou, Zixin Deng, Zhijun Wang (2012). Phosphorothioate DNA as an antioxidant in bacteria. Nucleic Acids Research.DOI
Jun Wu, Li Li, Zixin Deng, T. Mark Zabriskie, Xinyi He (2012). Analysis of the Mildiomycin Biosynthesis Gene Cluster in Streptoverticillum remofaciens ZJU5119 and Characterization of MilC, a Hydroxymethyl cytosyl‐glucuronic Acid Synthase. ChemBioChem.DOI
Fukun Chen, Zhenyi Zhang, Kui Lin, Tianle Qian, Yan Zhang, Delin You, Xinyi He, Zhijun Wang, Jingdan Liang, Zixin Deng, Geng Wu (2012). Crystal Structure of the Cysteine Desulfurase DndA from Streptomyces lividans Which Is Involved in DNA Phosphorothioation. PLoS ONE.DOI
Yun Fan, Yu-Mei Dai, Qiuxiang Cheng, Guangjun Zhang, Dongshu Zhang, Ping Fang, Hang Wu, Linquan Bai, Zixin Deng, Zhongjun Qin (2012). A self-ligation method for PCR-sequencing the telomeres of Streptomyces and Mycobacterium linear replicons. Journal of Microbiological Methods.DOI
Li Chen, Yemin Wang, Hang Guo, Min Xu, Zixin Deng, Meifeng Tao (2012). High-Throughput Screening for Streptomyces Antibiotic Biosynthesis Activators. Applied and Environmental Microbiology.DOI
Zhenhua Wei, Hang Wu, Linquan Bai, Zixin Deng, Jian‐Jiang Zhong (2012). Temperature shift-induced reactive oxygen species enhanced validamycin A production in fermentation of Streptomyces hygroscopicus 5008. Bioprocess and Biosystems Engineering.DOI
Pinglei Liu, Peng Li, Xiaofei Jiang, Dexi Bi, Yingzhou Xie, Cui Tai, Zixin Deng, Kumar Rajakumar, Hong‐Yu Ou (2012). Complete Genome Sequence of Klebsiella pneumoniae subsp. pneumoniae HS11286, a Multidrug-Resistant Strain Isolated from Human Sputum. Journal of Bacteriology.DOI
Weike Zhang, Lu Wang, Lingxin Kong, Tao Wang, Yiwen Chu, Zixin Deng, Delin You (2012). Unveiling the Post-PKS Redox Tailoring Steps in Biosynthesis of the Type II Polyketide Antitumor Antibiotic Xantholipin. Chemistry & Biology.DOI
Zhenhua Wei, Linquan Bai, Zixin Deng, Jian‐Jiang Zhong (2012). Impact of nitrogen concentration on validamycin A production and related gene transcription in fermentation of Streptomyces hygroscopicus 5008. Bioprocess and Biosystems Engineering.DOI
Mi-Jin Lee, Dekun Kong, Kyuboem Han, David H. Sherman, Linquan Bai, Zixin Deng, Shuangjun Lin, Eung Soo Kim (2012). Structural analysis and biosynthetic engineering of a solubility-improved and less-hemolytic nystatin-like polyene in Pseudonocardia autotrophica. Applied Microbiology and Biotechnology.DOI
Qian Liu, Fen Yao, Yit‐Heng Chooi, Qianjin Kang, Wei Xu, Yanran Li, Yucheng Shao, Yuefeng Shi, Zixin Deng, Yi Tang, Delin You (2012). Elucidation of Piericidin A1 Biosynthetic Locus Revealed a Thioesterase-Dependent Mechanism of α-Pyridone Ring Formation. Chemistry & Biology.DOI
Xun Guo, Tiangang Liu, Zixin Deng, David E. Cane (2012). Essential Role of the Donor Acyl Carrier Protein in Stereoselective Chain Translocation to a Fully Reducing Module of the Nanchangmycin Polyketide Synthase. Biochemistry.DOI
Dexi Bi, Linmeng Liu, Cui Tai, Zixin Deng, Kumar Rajakumar, Hong‐Yu Ou (2012). SecReT4: a web-based bacterial type IV secretion system resource. Nucleic Acids Research.DOI
Qing Yu, Linquan Bai, Xiufen Zhou, Zixin Deng (2011). Inactivation of the positive LuxR-type oligomycin biosynthesis regulators OlmRI and OlmRII increases avermectin production in Streptomyces avermitilis. Chinese Science Bulletin.DOI
Xiang Zhou, Hang Wu, Zhong Li, Xiufen Zhou, Linquan Bai, Zixin Deng (2011). Over-expression of UDP-glucose pyrophosphorylase increases validamycin A but decreases validoxylamine A production in Streptomyces hygroscopicus var. jinggangensis 5008. Metabolic Engineering.DOI
Qianjin Kang, Linquan Bai, Zixin Deng (2011). Toward steadfast growth of antibiotic research in China: From natural products to engineered biosynthesis. Biotechnology Advances.DOI
Tianpeng Gu, Fan Guo, Hui Yang, Hai-Ping Wu, Guifang Xu, Gui-Fang Xu, Wei Liu, Zhi-Guo Xie, Linyu Shi, Xinyi He, Seung‐Gi Jin, Khursheed Iqbal, Yujiang Geno Shi, Zixin Deng, Piroska E. Szabó, Gerd P. Pfeifer, Jinsong Li, Guoliang Xu, Guoliang Xu (2011). The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature.DOI
Hairong Cheng, Hengwei Wang, Jiyang Lv, Mingguo Jiang, Shuangjun Lin, Zixin Deng (2011). A novel method to prepare L-Arabinose from xylose mother liquor by yeast-mediated biopurification. Microbial Cell Factories.DOI
Peng Wang, Xue Gao, Yit‐Heng Chooi, Zixin Deng, Yi Tang (2011). Genetic characterization of enzymes involved in the priming steps of oxytetracycline biosynthesis in Streptomyces rimosus. Microbiology.DOI
Yan Li, Pei‐Ji Zhao, Qianjin Kang, Juan Ma, Linquan Bai, Zixin Deng (2011). Dual Carbamoylations on the Polyketide and Glycosyl Moiety by Asm21 Result in Extended Ansamitocin Biosynthesis. Chemistry & Biology.DOI
James R. Doroghazi, Kou‐San Ju, Daren W. Brown, David P. Labeda, Zixin Deng, William W. Metcalf, Wenqing Chen, Neil P. J. Price (2011). Genome Sequences of Three Tunicamycin-Producing Streptomyces Strains, S. chartreusis NRRL 12338, S. chartreusis NRRL 3882, and S. lysosuperificus ATCC 31396. Journal of Bacteriology.DOI
Qing Yu, Aiqin Du, Tiangang Liu, Zixin Deng, Xinyi He (2011). The biosynthesis of the polyether antibiotic nanchangmycin is controlled by two pathway-specific transcriptional activators. Archives of Microbiology.DOI
Hao Zhou, Yemin Wang, Yanfei Yu, Tingli Bai, Li Chen, Pei Liu, Hang Guo, Chenchen Zhu, Meifeng Tao, Zixin Deng (2011). A Non-Restricting and Non-Methylating Escherichia coli Strain for DNA Cloning and High-Throughput Conjugation to Streptomyces coelicolor. Current Microbiology.DOI
Fukun Chen, Kui Lin, Zhenyi Zhang, Leyi Chen, Xiaoshan Shi, Chunyang Cao, Zhijun Wang, Jingdan Liang, Zixin Deng, Geng Wu (2011). Purification, crystallization and preliminary X-ray analysis of the DndE protein fromSalmonella entericaserovar Cerro 87, which is involved in DNA phosphorothioation. Acta Crystallographica Section F Structural Biology and Crystallization Communications.DOI
Tao Wang, Linquan Bai, Dongqing Zhu, Lei Xuan, Guang Liu, Zixin Deng, Delin You (2011). Enhancing macrolide production in Streptomyces by coexpressing three heterologous genes. Enzyme and Microbial Technology.DOI
Jingfan Qiu, Ying Zhuo, Dongqing Zhu, Xiufen Zhou, Lixin Zhang, Linquan Bai, Zixin Deng (2011). Overexpression of the ABC transporter AvtAB increases avermectin production in Streptomyces avermitilis. Applied Microbiology and Biotechnology.DOI
Jun Yin, Zixin Deng, Guoping Zhao, Xi Huang (2011). The N-terminal Nucleophile Serine of Cephalosporin Acylase Executes the Second Autoproteolytic Cleavage and Acylpeptide Hydrolysis. Journal of Biological Chemistry.DOI
Tingting Huang, Yemin Wang, Jun Yin, Yanhua Du, Meifeng Tao, Jing Xu, Wenqing Chen, Shuangjun Lin, Zixin Deng (2011). Identification and Characterization of the Pyridomycin Biosynthetic Gene Cluster of Streptomyces pyridomyceticus NRRL B-2517. Journal of Biological Chemistry.DOI
Lianrong Wang, Shi Chen, Kevin L. Vergin, Stephen J. Giovannoni, Simon W. Chan, Michael S. DeMott, Koli Taghizadeh, Otto X. Cordero, Michael Cutler, Sonia C. Timberlake, Eric J. Alm, Martin F. Polz, Jarone Pinhassi, Zixin Deng, Peter C. Dedon (2011). DNA phosphorothioation is widespread and quantized in bacterial genomes. Proceedings of the National Academy of Sciences.DOI
Xiangzhao Mao, Shi Chen, Yaling Shen, Dongzhi Wei, Zixin Deng (2011). Effect of copper sulfate on biosynthesis of FR-008/Candicidin complex production in Streptomyces sp. World Journal of Microbiology and Biotechnology.DOI
Dexi Bi, Zhen Xu, Ewan M. Harrison, Cui Tai, Yiqing Wei, Xinyi He, Shiru Jia, Zixin Deng, Kumar Rajakumar, Hong‐Yu Ou (2011). ICEberg: a web-based resource for integrative and conjugative elements found in Bacteria. Nucleic Acids Research.DOI
Jinxia Lin, Linquan Bai, Zixin Deng, Jian‐Jiang Zhong (2010). Enhanced production of ansamitocin P-3 by addition of isobutanol in fermentation of Actinosynnema pretiosum. Bioresource Technology.DOI
Zhenhua Wei, Linquan Bai, Zixin Deng, Jian‐Jiang Zhong (2010). Enhanced production of validamycin A by H2O2-induced reactive oxygen species in fermentation of Streptomyces hygroscopicus 5008. Bioresource Technology.DOI
Guang Liu, Hong‐Yu Ou, Tao Wang, Li Li, Huarong Tan, Xiufen Zhou, Kumar Rajakumar, Zixin Deng, Xinyi He (2010). Cleavage of Phosphorothioated DNA and Methylated DNA by the Type IV Restriction Endonuclease ScoMcrA. PLoS Genetics.DOI
Lin Cheng, Wenqing Chen, Lipeng Zhai, Dongmei Xu, Tingting Huang, Shuangjun Lin, Xiufen Zhou, Zixin Deng (2010). Identification of the genecluster involved in muraymycin biosynthesis from Streptomyces sp. NRRL 30471. Molecular BioSystems.DOI
Jie Zhang, Jon Jurriaan van Aartsen, Xiaofei Jiang, Yucheng Shao, Cui Tai, Xinyi He, Zhilei Tan, Zixin Deng, Shiru Jia, Kumar Rajakumar, Hong‐Yu Ou (2010). Expansion of the known Klebsiella pneumoniae species gene pool by characterization of novel alien DNA islands integrated into tmRNA gene sites. Journal of Microbiological Methods.DOI
Qiulin Wu, Jingdan Liang, Shuangjun Lin, Xiufen Zhou, Linquan Bai, Zixin Deng, Zhijun Wang (2010). Characterization of the Biosynthesis Gene Cluster for the Pyrrole Polyether Antibiotic Calcimycin (A23187) in Streptomyces chartreusis NRRL 3882. Antimicrobial Agents and Chemotherapy.DOI
Wenqing Chen, Dongjing Qu, Lipeng Zhai, Meifeng Tao, Yemin Wang, Shuangjun Lin, Neil P. J. Price, Zixin Deng (2010). Characterization of the tunicamycin gene cluster unveiling unique steps involved in its biosynthesis. Protein & Cell.DOI
Jongtae Yang, Hui Min Xu, Yirong Zhang, Linquan Bai, Zixin Deng, Taifo Mahmud (2010). Nucleotidylation of unsaturated carbasugar in validamycin biosynthesis. Organic & Biomolecular Chemistry.DOI
Yucheng Shao, Ewan M. Harrison, Dexi Bi, Cui Tai, Xinyi He, Hong‐Yu Ou, Kumar Rajakumar, Zixin Deng (2010). TADB: a web-based resource for Type 2 toxin–antitoxin loci in bacteria and archaea. Nucleic Acids Research.DOI
Xun Guo, Tiangang Liu, Chiara R. Valenzano, Zixin Deng, David E. Cane (2010). Mechanism and Stereospecificity of a Fully Saturating Polyketide Synthase Module: Nanchangmycin Synthase Module 2 and Its Dehydratase Domain. Journal of the American Chemical Society.DOI
Jayavel Sridhar, Narmada Sambaturu, Radhakrishna Sabarinathan, Hong‐Yu Ou, Zixin Deng, K. Sekar, Ziauddin Ahamed Rafi, Kumar Rajakumar (2010). Correction: sRNAscanner: A Computational Tool for Intergenic Small RNA Detection in Bacterial Genomes. PLoS ONE.DOI
Changming Zhao, Tingting Huang, Wenqing Chen, Zixin Deng (2010). Enhancement of the Diversity of Polyoxins by a Thymine-7-Hydroxylase Homolog outside the Polyoxin Biosynthesis Gene Cluster. Applied and Environmental Microbiology.DOI
Jayavel Sridhar, Suryanarayanan Ramkumar Narmada, Radhakrishnan Sabarinathan, Hong‐Yu Ou, Zixin Deng, K. Sekar, Ziauddin Ahamed Rafi, Kumar Rajakumar (2010). sRNAscanner: A Computational Tool for Intergenic Small RNA Detection in Bacterial Genomes. PLoS ONE.DOI
Tiegang Xu, Fen Yao, Xiufen Zhou, Zixin Deng, Delin You (2010). A novel host-specific restriction system associated with DNA backbone S-modification in Salmonella. Nucleic Acids Research.DOI
Yucheng Shao, Xinyi He, Ewan M. Harrison, Cui Tai, Hong‐Yu Ou, Kumar Rajakumar, Zixin Deng (2010). mGenomeSubtractor: a web-based tool for parallel in silico subtractive hybridization analysis of multiple bacterial genomes. Nucleic Acids Research.DOI
Chunhua Zhao, Jane M. Coughlin, Jianhua Ju, Dongqing Zhu, Evelyn Wendt-Pienkowski, Xiufen Zhou, Zhijun Wang, Ben Shen, Zixin Deng (2010). Oxazolomycin Biosynthesis in Streptomyces albus JA3453 Featuring an “Acyltransferase-less” Type I Polyketide Synthase That Incorporates Two Distinct Extender Units. Journal of Biological Chemistry.DOI
Zhonghui Gai, Xiaoyu Wang, Xiaorui Liu, Cui Tai, Hongzhi Tang, Xiaofei He, Geng Wu, Zixin Deng, Ping Xu (2010). The Genes Coding for the Conversion of Carbazole to Catechol Are Flanked by IS6100 Elements in Sphingomonas sp. Strain XLDN2-5. PLoS ONE.DOI
Yunlong He, Yuhui Sun, Tiangang Liu, Xiufen Zhou, Linquan Bai, Zixin Deng (2010). Cloning of Separate Meilingmycin Biosynthesis Gene Clusters by Use of Acyltransferase-Ketoreductase Didomain PCR Amplification. Applied and Environmental Microbiology.DOI
Ewan M. Harrison, Melissa Carter, Shelley N. Luck, Hong‐Yu Ou, Xinyi He, Zixin Deng, Chris O’Callaghan, Aras Kadioglu, Kumar Rajakumar (2010). Pathogenicity Islands PAPI-1 and PAPI-2 Contribute Individually and Synergistically to the Virulence of Pseudomonas aeruginosa Strain PA14. Infection and Immunity.DOI
Jinxia Lin, Linquan Bai, Zixin Deng, Jian‐Jiang Zhong (2010). Effect of ammonium in medium on ansamitocin P-3 production by Actinosynnema pretiosum. Biotechnology and Bioprocess Engineering.DOI
Shi Chen, Lianrong Wang, Zixin Deng (2010). Twenty years hunting for sulfur in DNA. Protein & Cell.DOI
Yirong Zhang, Linquan Bai, Zixin Deng (2009). Functional characterization of the first two actinomycete 4-amino-4-deoxychorismate lyase genes. Microbiology.DOI
Rui Li, Zhoujie Xie, Yuqing Tian, Haihua Yang, Wenqing Chen, Delin You, Gang Liu, Zixin Deng, Huarong Tan (2009). polR, a pathway-specific transcriptional regulatory gene, positively controls polyoxin biosynthesis in Streptomyces cacaoi subsp. asoensis. Microbiology.DOI
Yueqiao Liao, Zhenhua Wei, Linquan Bai, Zixin Deng, Jian‐Jiang Zhong (2009). Effect of fermentation temperature on validamycin A production by Streptomyces hygroscopicus 5008. Journal of Biotechnology.DOI
Lei Li, Linquan Bai, Xiufen Zhou, Zixin Deng (2009). Enhanced validamycin production and gene expression at elevated temperature in Streptomyces hygroscopicus subsp. jingangensis 5008. 《中国科学通报：英文版》.DOI
Rui Li, Gang Liu, Zhoujie Xie, Xihong He, Wenqing Chen, Zixin Deng, Huarong Tan (2009). PolY, a transcriptional regulator with ATPase activity, directly activates transcription of polR in polyoxin biosynthesis in Streptomyces cacaoi. Molecular Microbiology.DOI
Nan Chen, Hong‐Yu Ou, Jon Jurriaan van Aartsen, Xiaofei Jiang, Min Li, Zehua Yang, Quhao Wei, Xiaoyun Chen, Xinyi He, Zixin Deng, Kumar Rajakumar, Yuan Lu (2009). The pheV Phenylalanine tRNA Gene in Klebsiella pneumoniae Clinical Isolates Is an Integration Hotspot for Possible Niche-Adaptation Genomic Islands. Current Microbiology.DOI
Zhenhua Wei, Linquan Bai, Zixin Deng, Jian‐Jiang Zhong (2009). H2O2-induced reactive oxygen species regulated gene transcription, enzyme activity and validamycin A biosynthesis by Streptomyces hygroscopicus 5008. Journal of Bioscience and Bioengineering.DOI
Qinggang Li, Xiaoyu Wang, Guangbo Yin, Zhonghui Gai, Hongzhi Tang, Cuiqing Ma, Zixin Deng, Ping Xu (2009). New Metabolites in Dibenzofuran Cometabolic Degradation by a Biphenyl-Cultivated Pseudomonas putida Strain B6-2. Environmental Science & Technology.DOI
Hairong Cheng, Zilong Li, Ning Jiang, Zixin Deng (2009). Cloning, Purification and Characterization of an NAD-Dependent d-Arabitol Dehydrogenase from Acetic Acid Bacterium, Acetobacter suboxydans. The Protein Journal.DOI
Jingdan Liang, Qiule Niu, Xinping Xu, Yuanming Luo, Xiufen Zhou, Zixin Deng, Zhijun Wang (2009). Effective elimination of nucleic acids from bacterial protein samples for optimized blue native polyacrylamide gel electrophoresis. Electrophoresis.DOI
Hui Min Xu, Yirong Zhang, Jongtae Yang, Taifo Mahmud, Linquan Bai, Zixin Deng (2009). Alternative Epimerization in C7N-Aminocyclitol Biosynthesis Is Catalyzed by ValD, A Large Protein of the Vicinal Oxygen Chelate Superfamily. Chemistry & Biology.DOI
Hong‐Yu Ou, Xinyi He, Yu‐Cheng Shao, Cui Tai, Kumar Rajakumar, Zixin Deng (2009). dndDB: A Database Focused on Phosphorothioation of the DNA Backbone. PLoS ONE.DOI
Wenqing Chen, Tingting Huang, Xinyi He, Qingqing Meng, Delin You, Linquan Bai, Jialiang Li, Mingxuan Wu, Rui Li, Zhoujie Xie, Huchen Zhou, Xiufen Zhou, Huarong Tan, Zixin Deng (2009). Characterization of the Polyoxin Biosynthetic Gene Cluster from Streptomyces cacaoi and Engineered Production of Polyoxin H. Journal of Biological Chemistry.DOI
Tiegang Xu, Jingdan Liang, Shi Chen, Lianrong Wang, Xinyi He, Delin You, Zhijun Wang, Aiying Li, Zhongli Xu, Xiufen Zhou, Zixin Deng (2009). DNA phosphorothioation in Streptomyces lividans: mutational analysis of the dnd locus. BMC Microbiology.DOI
Fen Yao, Tiegang Xu, Xiufen Zhou, Zixin Deng, Delin You (2009). Functional analysis of spfD gene involved in DNA phosphorothioation in Pseudomonas fluorescens Pf0‐1. FEBS Letters.DOI
Shi Chen, Xiangzhao Mao, Yaling Shen, Yongjun Zhou, Jialiang Li, Lianrong Wang, Xinyi Tao, Liang Yang, Yuxiao Wang, Xiufen Zhou, Zixin Deng, Dongzhi Wei (2009). Tailoring the P450 Monooxygenase Gene for FR-008/Candicidin Biosynthesis. Applied and Environmental Microbiology.DOI
Zhonghui Gai, Bo Yu, Xiaoyu Wang, Zixin Deng, Ping Xu (2008). Microbial transformation of benzothiophenes, with carbazole as the auxiliary substrate, by Sphingomonas sp. strain XLDN2-5. Microbiology.DOI
Zixin Deng (2008). DNA phosphorothioate modification and its biol-biotech implications. Journal of Biotechnology.DOI
Li Sun, Wenqing Chen, Zixin Deng, Jian-Jiang-Zhong (2008). Microbiological assay for the quantitative determination of polyoxin B. Journal of Biotechnology.DOI
Yueqiao Liao, Linquan Bai, Zixin Deng, Jian‐Jiang Zhong (2008). Fermentation temperature is significant to validamycin a biosynthesis by Streptomyces hygroscopicus 5008. Journal of Biotechnology.DOI
Xiangzhao Mao, Liang Yang, Lujia Zhang, Shi Chen, Yaling Shen, Zixin Deng, Dongzhi Wei (2008). Stimulatory effect of copper ion on the biosynthesis of the novel Candicidin/Fr-008 derivative CS101 in a mutant of Streptomyces sp. FR-008. Journal of Biotechnology.DOI
Zixin Deng, Linquan Bai (2008). Metabolic engineering for antibiotics discovery and production. Journal of Biotechnology.DOI
Yuhui Sun, Xinyi He, Jingdan Liang, Xiufen Zhou, Zixin Deng (2008). Analysis of functions in plasmid pHZ1358 influencing its genetic and structural stability in Streptomyces lividans 1326. Applied Microbiology and Biotechnology.DOI
Li Sun, Wenqing Chen, Zixin Deng, Jian‐Jiang Zhong (2008). Microbiological assay for quantitative determination of polyoxin B. Process Biochemistry.DOI
Yongjun Zhou, Qingqing Meng, Delin You, Jialiang Li, Shi Chen, Dazhong Ding, Xiufen Zhou, Huchen Zhou, Linquan Bai, Zixin Deng (2008). Selective Removal of Aberrant Extender Units by a Type II Thioesterase for Efficient FR-008/Candicidin Biosynthesis in Streptomyces sp. Strain FR-008. Applied and Environmental Microbiology.DOI
Hui Min Xu, Jongtae Yang, Linquan Bai, Zixin Deng, Taifo Mahmud (2008). Genetically engineered production of 1,1′-bis-valienamine and validienamycin in Streptomyces hygroscopicus and their conversion to valienamine. Applied Microbiology and Biotechnology.DOI
Pei‐Ji Zhao, Linquan Bai, Juan Ma, Ying Zeng, Lei Li, Yirong Zhang, Chunhua Lu, Huanqin Dai, Zhaoxian Wu, Yaoyao Li, Xuan Wu, Gang Chen, Xiao‐Jiang Hao, Yuemao Shen, Zixin Deng, Heinz G. Floss (2008). Amide N-Glycosylation by Asm25, an N-Glycosyltransferase of Ansamitocins. Chemistry & Biology.DOI
Delin You, Tiegang Xu, Fen Yao, Xiufen Zhou, Zixin Deng (2008). Direct Evidence that ThiI is an ATP Pyrophosphatase for the Adenylation of Uridine in 4‐Thiouridine Biosynthesis. ChemBioChem.DOI
Hui Min Xu, Kazuyuki Minagawa, Linquan Bai, Zixin Deng, Taifo Mahmud (2008). Catalytic Analysis of the Validamycin Glycosyltransferase (ValG) and Enzymatic Production of 4′′-epi-Validamycin A. Journal of Natural Products.DOI
Yongjun Zhou, Jialiang Li, Jing Zhu, Shi Chen, Linquan Bai, Xiufen Zhou, Houming Wu, Zixin Deng (2008). Incomplete β-Ketone Processing as a Mechanism for Polyene Structural Variation in the FR-008/Candicidin Complex. Chemistry & Biology.DOI
Hongbin Xu, Keith Frederick Chater, Zixin Deng, Meifeng Tao (2008). A Cellulose Synthase-Like Protein Involved in Hyphal Tip Growth and Morphological Differentiation in Streptomyces. Journal of Bacteriology.DOI
Tiangang Liu, Xin Lin, Xiufen Zhou, Zixin Deng, David E. Cane (2008). Mechanism of Thioesterase-Catalyzed Chain Release in the Biosynthesis of the Polyether Antibiotic Nanchangmycin. Chemistry & Biology.DOI
Li Li, Zhinan Xu, Xiaoying Xu, Jun Wu, Yun Zhang, Xinyi He, T. Mark Zabriskie, Zixin Deng (2008). The Mildiomycin Biosynthesis: Initial Steps for Sequential Generation of 5‐Hydroxymethylcytidine 5′‐Monophosphate and 5‐Hydroxymethylcytosine in Streptoverticillium rimofaciens ZJU5119. ChemBioChem.DOI
Hongzhi Tang, Shuning Wang, Lanying Ma, Xiang‐Zhou Meng, Zixin Deng, Dake Zhang, Cuiqing Ma, Ping Xu (2008). A Novel Gene, Encoding 6-Hydroxy-3-Succinoylpyridine Hydroxylase, Involved in Nicotine Degradation by Pseudomonas putida Strain S16. Applied and Environmental Microbiology.DOI
Dongliang Hua, Cuiqing Ma, Shan Lin, Lifu Song, Zixin Deng, Zarao Maomy, Zhaobin Zhang, Bo Yu, Ping Xu (2007). Biotransformation of isoeugenol to vanillin by a newly isolated Bacillus pumilus strain: Identification of major metabolites. Journal of Biotechnology.DOI
Hong‐Yu Ou, Cindy Teh Shuan Ju, Kwai Lin Thong, Norazah Ahmad, Zixin Deng, Michael R. Barer, Kumar Rajakumar (2007). Translational Genomics to Develop a Salmonella enterica Serovar Paratyphi A Multiplex Polymerase Chain Reaction Assay. Journal of Molecular Diagnostics.DOI
Lianrong Wang, Shi Chen, Tiegang Xu, Koli Taghizadeh, John S. Wishnok, Xiufen Zhou, Delin You, Zixin Deng, Peter C. Dedon (2007). Phosphorothioation of DNA in bacteria by dnd genes. Nature Chemical Biology.DOI
Xinyi He, Hong‐Yu Ou, Qing Yu, Xiufen Zhou, Jun Wu, Jingdan Liang, Wei Zhang, Kumar Rajakumar, Zixin Deng (2007). Analysis of a genomic island housing genes for DNA S‐modification system inStreptomyces lividans66 and its counterparts in other distantly related bacteria. Molecular Microbiology.DOI
Barbara M. Harvey, Tatiana Mironenko, Yuhui Sun, Hui Hong, Zixin Deng, Peter F. Leadlay, Kira J. Weissman, Stephen F. Haydock (2007). Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137. Chemistry & Biology.DOI
Delin You, Lianrong Wang, Fen Yao, Xiufen Zhou, Zixin Deng (2007). A Novel DNA Modification by Sulfur: DndA Is a NifS-like Cysteine Desulfurase Capable of Assembling DndC as an Iron−Sulfur Cluster Protein in Streptomyces lividans. Biochemistry.DOI
Kazuyuki Minagawa, Yirong Zhang, Takuya Ito, Linquan Bai, Zixin Deng, Taifo Mahmud (2007). ValC, a New Type of C7‐Cyclitol Kinase Involved in the Biosynthesis of the Antifungal Agent Validamycin A. ChemBioChem.DOI
Zhonghui Gai, Bo Yu, Fuli Li, Ying Wang, Cuiqing Ma, Jinhui Feng, Zixin Deng, Ping Xu (2007). Cometabolic Degradation of Dibenzofuran and Dibenzothiophene by a Newly Isolated Carbazole-Degrading Sphingomonas sp. Strain. Applied and Environmental Microbiology.DOI
Xiangzhao Mao, Yaling Shen, Liang Yang, Shi Chen, Yuping Yang, Jingya Yang, Hu Zhu, Zixin Deng, Dongzhi Wei (2007). Optimizing the medium compositions for accumulation of the novel FR-008/Candicidin derivatives CS101 by a mutant of Streptomyces sp. using statistical experimental methods. Process Biochemistry.DOI
Zixin Deng, Linquan Bai (2007). Antibiotic Biosynthetic Pathways and Pathway Engineering — A Growing Research Field in China. ChemInform.DOI
Lei Wang, Yanfei Yu, Xinyi He, Xiufen Zhou, Zixin Deng, Keith Frederick Chater, Meifeng Tao (2007). Role of an FtsK-Like Protein in Genetic Stability inStreptomyces coelicolorA3(2). Journal of Bacteriology.DOI
Hong‐Yu Ou, Xuesong He, Ewan M. Harrison, Bridget R. Kulasekara, Ali Salman Bin Thani, Aras Kadioglu, Stephen Lory, Jay C. D. Hinton, Michael R. Barer, Zixin Deng, Kumar Rajakumar (2007). MobilomeFINDER: web-based tools for in silico and experimental discovery of bacterial genomic islands. Nucleic Acids Research.DOI
Zixin Deng (2007). Training Innovative Talents in Laboratory. Research and Exploration in Laboratory.
Zixin Deng (2007). Trainning Innovative Talents in Laboratory (Continued). Research and Exploration in Laboratory.
Wencheng Li, Ying Xin, Guo Yuzheng, Zhen Yu, Xiufen Zhou, Zixin Deng, Helen M. Kieser, Keith Frederick Chater, Meifeng Tao (2006). Identification of a Gene Negatively Affecting Antibiotic Production and Morphological Differentiation inStreptomyces coelicolorA3(2). Journal of Bacteriology.DOI
Dongliang Hua, Cuiqing Ma, Lifu Song, Shan Lin, Zhaobin Zhang, Zixin Deng, Ping Xu (2006). Enhanced vanillin production from ferulic acid using adsorbent resin. Applied Microbiology and Biotechnology.DOI
Wencheng Li, Jing Wu, Weixin Tao, Chunhua Zhao, Yemin Wang, Xinyi He, Govind Chandra, Xiufen Zhou, Zixin Deng, Keith Frederick Chater, Meifeng Tao (2006). A genetic and bioinformatic analysis ofStreptomyces coelicolorgenes containing TTA codons, possible targets for regulation by a developmentally significant tRNA. FEMS Microbiology Letters.DOI
Tiangang Liu, Delin You, Chiara R. Valenzano, Yuhui Sun, Jialiang Li, Qing Yu, Xiufen Zhou, David E. Cane, Zixin Deng (2006). Identification of NanE as the Thioesterase for Polyether Chain Release in Nanchangmycin Biosynthesis. Chemistry & Biology.DOI
Pieter C. Dorrestein, Steven G. Van Lanen, Wenli Li, Chunhua Zhao, Zixin Deng, Ben Shen, Neil L. Kelleher (2006). The Bifunctional Glyceryl Transferase/Phosphatase OzmB Belonging to the HAD Superfamily That Diverts 1,3-Bisphosphoglycerate into Polyketide Biosynthesis. Journal of the American Chemical Society.DOI
Chunhua Zhao, Jianhua Ju, Steven D. Christenson, Wyatt C. Smith, Danfeng Song, Xiufen Zhou, Ben Shen, Zixin Deng (2006). Utilization of the Methoxymalonyl-Acyl Carrier Protein Biosynthesis Locus for Cloning the Oxazolomycin Biosynthetic Gene Cluster from Streptomyces albus JA3453. Journal of Bacteriology.DOI
Lianrong Wang, Shi Chen, Xiang Xiao, Xi Xiao Huang, Delin You, Xiufen Zhou, Zixin Deng (2006). arsRBOCT Arsenic Resistance System Encoded by Linear Plasmid pHZ227 in Streptomyces sp. Strain FR-008. Applied and Environmental Microbiology.DOI
Linquan Bai, Lei Li, Hui Min Xu, Kazuyuki Minagawa, Yi Yu, Yirong Zhang, Xiufen Zhou, Heinz G. Floss, Taifo Mahmud, Zixin Deng (2006). Functional Analysis of the Validamycin Biosynthetic Gene Cluster and Engineered Production of Validoxylamine A. Chemistry & Biology.DOI
Zixin Deng, Linquan Bai (2006). Antibiotic biosynthetic pathways and pathway engineering—a growing research field in China. Natural Product Reports.DOI
Yi Yu, Linquan Bai, Kazuyuki Minagawa, Xiao‐Hong Jian, Lei Li, Jialiang Li, Shuangya Chen, Erhu Cao, Taifo Mahmud, Heinz G. Floss, Xiufen Zhou, Zixin Deng (2005). Gene Cluster Responsible for Validamycin Biosynthesis in Streptomyces hygroscopicus subsp. jinggangensis 5008. Applied and Environmental Microbiology.DOI
Xiufen Zhou, Xinyi He, Jingdan Liang, Aiying Li, Tiegang Xu, Tobias Kieser, John D. Helmann, Zixin Deng (2005). A novel DNA modification by sulphur. Molecular Microbiology.DOI
Dongqing Zhu, Xinyi He, Xiufen Zhou, Zixin Deng (2005). Expression of the melC Operon in Several Streptomyces Strains Is Positively Regulated by AdpA, an AraC Family Transcriptional Regulator Involved in Morphological Development in Streptomyces coelicolor. Journal of Bacteriology.DOI
Xiufen Zhou, Xinyi He, Aiying Li, Fang Lei, Tobias Kieser, Zixin Deng (2004). Streptomyces coelicolor A3(2) Lacks a Genomic Island Present in the Chromosome of Streptomyces lividans 66. Applied and Environmental Microbiology.DOI
Lei Qin, Hengan Wang, Zhongqin Wu, Xiaofeng Zhang, Meilei Jin, Zixin Deng, Guoping Zhao (2004). Identification and Characterization of hmr19 Gene Encoding a Multidrug Resistance Efflux Protein from Streptomyces hygroscopicus subsp. yingchengensis Strain 10–22. Acta Biochimica et Biophysica Sinica.DOI
Xiaohua Li, Xiufen Zhou, Zixin Deng (2004). Isolation and Characterization of Micromonospora Phage ΦHAU8 and Development into a Phasmid. Applied and Environmental Microbiology.DOI
Xiaohua Li, Xiufen Zhou, Zixin Deng (2003). Vector Systems Allowing Efficient Autonomous or Integrative Gene Cloning inMicromonosporasp. Strain 40027. Applied and Environmental Microbiology.DOI
Shi Chen, Xi Xiao Huang, Xiufen Zhou, Linquan Bai, Jing He, Ki Jun Jeong, Sang Yup Lee, Zixin Deng (2003). Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex. Chemistry & Biology.DOI
Eriko Takano, Meifeng Tao, Fei Long, Maureen J. Bibb, L. Wang, Wenhao Li, Mark J. Buttner, Mervyn J. Bibb, Zixin Deng, Keith Frederick Chater (2003). A rare leucine codon in adpA is implicated in the morphological defect of bldA mutants of Streptomyces coelicolor. Molecular Microbiology.DOI
Yuhui Sun, Xiufen Zhou, TU Guo-quan, Zixin Deng (2003). Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226. Archives of Microbiology.DOI
Yuhui Sun, Xiufen Zhou, Hui Fen Dong, TU Guo-quan, Min Wang, Bofei Wang, Zixin Deng (2003). A Complete Gene Cluster from Streptomyces nanchangensis NS3226 Encoding Biosynthesis of the Polyether Ionophore Nanchangmycin. Chemistry & Biology.DOI
Yuhui Sun, Xiufen Zhou, Jun Liu, Kai Bao, Guiming Zhang, TU Guo-quan, Tobias Kieser, Zixin Deng (2002). ‘Streptomyces nanchangensis’, a producer of the insecticidal polyether antibiotic nanchangmycin and the antiparasitic macrolide meilingmycin, contains multiple polyketide gene clusters. Microbiology.DOI
Xiuhua Pang, Xiufen Zhou, Yuhui Sun, Zixin Deng (2002). Physical Map of the Linear Chromosome of Streptomyces hygroscopicus 10-22 Deduced by Analysis of Overlapping Large Chromosomal Deletions. Journal of Bacteriology.DOI
Yiqun Wang, Yang Xu, Feng Yu, Zixin Deng, Shuangjun Lin, Jianting Zheng (2023). Structural Basis of Streptomyces Antibiotic Regulatory Proteins Activating Transcription. bioRxiv (Cold Spring Harbor Laboratory).DOI
Tingting Huang, Zihua Zhou, Maolong Wei, Lin Chen, Zhihong Xiao, Zixin Deng, Shuangjun Lin (2021). Characterization of pyridomycin B reveals the formation of functional groups in antimycobacterial pyridomycin. bioRxiv (Cold Spring Harbor Laboratory).DOI
Sushu Hu, Wanli Peng, Shuangjun Lin, Zixin Deng, Rubing Liang (2021). The transcriptome analysis of Escherichia coli responding to tellurite. Research Square.DOI
Sicong Li, Priscila dos Santos Bury, Fanglu Huang, Junhong Guo, Guo Sun, Anna Reva, Chuan Huang, Xinyun Jian, Yuan Li, Jiahai Zhou, Zixin Deng, Finian James Leeper, Peter F. Leadlay, M.V.B. Dias, Yuhui Sun (2021). Mechanistic Insights into Dideoxygenation in Gentamicin Biosynthesis. Research Square.DOI
Ming Wang, Aisi Fu, Ben Hu, Gaigai Shen, Ran Liu, Wanxu Zhao, Shupeng Jiang, Xuan Cai, Congrong Li, Juan Li, Qing Wu, Kai Feng, Jiashuang Gu, Jia Chen, Mingyue Shu, Binghong Zhang, Zixin Deng, Lilei Yu, Yan Li, Tiangang Liu (2020). Same-Day Simultaneous Diagnosis of Bacterial and Fungal Infections in Clinical Practice by Nanopore Targeted Sequencing. medRxiv.DOI
Qian Liu, Xiang Guo, Guanhua Xun, Zhonglei Li, Yuesheng Chong, Litao Yang, Hongxia Wang, Fengchun Zhang, Shukun Luo, Zixin Deng, Kai Li, Yan Fang Feng (2019). Argonaute-mediated system for supersensitive and multiplexed detection of rare mutations. bioRxiv (Cold Spring Harbor Laboratory).DOI
Ran Liu, Yuchen Zhang, Guoqing Zhai, Shuai Fu, Xia Yao, Ben Hu, Xuan Cai, Yan Zhang, Yan Li, Zixin Deng, Tiangang Liu (2019). A cell-free platform based on nisin biosynthesis for discovering novel lanthipeptides and guiding their overproduction in vivo. bioRxiv (Cold Spring Harbor Laboratory).DOI
Xi Huang, Jun Yin, Weihong Jiang, Zixin Deng, Guoping Zhao (2008). Substrate entering and product leaving trajectories predict an engulfing dynamic for the major conformational change of the &946;-lactam acylase. Nature Precedings.DOI
书籍章节
Lianrong Wang, Shi Chen, Zixin Deng (2011). Phosphorothioation: An Unusual Post-Replicative Modification on the DNA Backbone. InTech eBooks.DOI
Xiangzhao Mao, Feng Wang, Jianguo Zhang, Shi Chen, Zixin Deng, Yaling Shen, Dongzhi Wei (2009). The pH Shift and Precursor Feeding Strategy in a Low-Toxicity FR-008/Candicidin Derivative CS103 Fermentation Bioprocess by a Mutant of Streptomyces sp. FR-008. Applied Biochemistry and Biotechnology.DOI
Tiangang Liu, David E. Cane, Zixin Deng (2009). Chapter 9 The Enzymology of Polyether Biosynthesis. Methods in enzymology on CD-ROM/Methods in enzymology.DOI
Xiao‐Hong Jian, Xiuhua Pang, Yi Yu, Xiufen Zhou, Zixin Deng (2006). Identification of genes necessary for jinggangmycin biosynthesis from Streptomyces hygroscopicus 10-22. Antonie van Leeuwenhoek.DOI