郭喻｜武汉大学｜学者主页

2025

孕期对乙酰氨基酚暴露致发育毒性及其机制研究进展

梅昊楠，张子依，王昱希，汪晖，郭喻

《中国药物警戒》

DOI

2025

Prenatal acetaminophen exposure induces changes of placental morphology and function and its influencing factors

Ziyi Zhang, Yuxi Wang, Yuxi Wang, Yu Guo, Zheng He, Hui Wang

Food and Chemical Toxicology

DOI

2025

Embryonic exposure to prednisone induces bone developmental toxicity in zebrafish: Characteristics and molecular mechanisms

Jiaqi Wang, Jiaqi Wang, Yangfan Shangguan, Fei Long, Yu Guo, Hui Wang, Liaobin Chen

Journal of Hazardous Materials

DOI

2024

核受体在胎源性非酒精性脂肪肝病中的作用

龚正，戴永国，郭麒，孙潇翔，郭喻

《生命科学》

2024

Sperm miR‐142‐3p Reprogramming Mediates Paternal Pre‐Pregnancy Caffeine Exposure‐Induced Non‐Alcoholic Steatohepatitis in Male Offspring Rats

Cong Zhang, Yu Guo, Yi Liu, Kexin Liu, Wen Hu, Hui Wang

Advanced Science

DOI

2024

The characterization of developmental toxicity in fetal offspring induced by acetaminophen exposure during pregnancy

Ze Chen, Xiaoxiang Sun, Yi Liu, Xiaoqi Zhao, Yu Guo, Hui Wang

Ecotoxicology and Environmental Safety

DOI

2024

Prenatal acetaminophen exposure and the developing ovary: Time, dose, and course consequences for fetal mice

Tiancheng Wu, Jing Huang, Yating Li, Yu Guo, Hui Wang, Yuanzhen Zhang

Food and Chemical Toxicology

DOI

2023

Glucocorticoids and intrauterine programming of nonalcoholic fatty liver disease

Ze Chen, Liping Xia, Lang Shen, Dan Xu, Yu Guo, Hui Wang

Metabolism

DOI

2023

Prenatal exposure to acetaminophen at different doses, courses and time causes testicular dysplasia in offspring mice and its mechanism

Yi Liu, Yi Liu, Sijia Chen, Ziyu Kong, Yu Guo, Hui Wang

Chemosphere

DOI

2023

Lactational retrorsine exposure changes maternal milk components and disturbs metabolism homeostasis of offspring rats

Yongguo Dai, Qi Guo, Kequan Xu, Zheng Gong, Shuaikai Qiu, Xiaoxiang Sun, Jie Liu, Di Wang, Zhixin Yang, Hui Wang, Yu Guo

The Science of The Total Environment

DOI

2023

Prenatal exposure to corn oil, CMC-Na or DMSO affects physical development and multi-organ functions in fetal mice

Kaiqi Chen, Xiaoqian Lu, Dan Xu, Yu Guo, Ying Ao, Hui Wang

Reproductive Toxicology

DOI

2023

Intrauterine developmental origin, programming mechanism, and prevention strategy of fetal‐originated hypercholesterolemia

Kexin Liu, Ze Chen, Wen Hu, Bo He, Dan Xu, Yu Guo, Hui Wang

Obesity Reviews

DOI

2023

Course-, dose-, and stage-dependent toxic effects of prenatal acetaminophen exposure on fetal long bone development

Chi Ma, Xufeng Li, Hao Xiao, Bin Li, Hanwen Gu, Yu Guo, Hui Wang, Yinxian Wen, Liaobin Chen

Toxicology Letters

DOI

2022

Prenatal ethanol exposure induces dynamic changes of expression and activity of hepatic cytochrome P450 isoforms in male rat offspring

Xiaoxiang Sun, Liang He, Huichang Bi, Min Huang, E. Xiang, Xia Li, Hui Wang, Yu Guo

Reproductive Toxicology

DOI

2022

Prenatal dexamethasone exposure induced pancreatic β-cell dysfunction and glucose intolerance of male offspring rats: Role of the epigenetic repression of ACE2

Yongguo Dai, Hao Kou, Shuxia Gui, Xiao-Ling Guo, Heze Liu, Zheng Gong, Xiaoxiang Sun, Hui Wang, Yu Guo

The Science of The Total Environment

DOI

2022

Prenatal smoke (Nicotine) exposure and offspring's metabolic disease susceptibility in adulthood

Bo He, Zhang Qi, Yu Guo, Ying Ao, Kai Tie, Hao Xiao, Liaobin Chen, Dan Xu, Hui Wang

Food and Chemical Toxicology

DOI

2022

Developmental toxicity and programming alterations of multiple organs in offspring induced by medication during pregnancy

Zhengjie Lu, Yu Guo, Dan Xu, Hao Xiao, Yongguo Dai, Kexin Liu, Liaobin Chen, Hui Wang

Acta Pharmaceutica Sinica B

DOI

2021

母乳成分改变影响子代脂肪肝发生的研究进展

郭麒，许珂铨，戴永国，汪晖，郭喻

《生命科学》

DOI

2021

Identification and validation of reference genes for RT-qPCR analysis in fetal rat pancreas

Yongguo Dai, Hao Kou, Xiao-Ling Guo, Zheng Gong, Heze Liu, Yi Liu, Hui Wang, Yu Guo

Reproductive Toxicology

DOI

2021

Prenatal Exposure to Retrorsine Induces Developmental Toxicity and Hepatotoxicity of Fetal Rats in a Sex-Dependent Manner: The Role of Pregnane X Receptor Activation

Yongguo Dai, Jinyuan Luo, E Xiang, Qi Guo, Zheng He, Zheng Gong, Xiaoxiang Sun, Hao Kou, Kequan Xu, Chengpeng Fan, Jie Liu, Shuaikai Qiu, Yanqing Wang, Hui Wang, Yu Guo

Journal of Agricultural and Food Chemistry

DOI

2020

表观遗传修饰在胰腺β细胞分化和功能中的作用

戴永国，寇皓，桂淑霞，汪晖，郭喻

《生命科学》

DOI

2020

Epigenetic repression of AT2 receptor is involved in β cell dysfunction and glucose intolerance of adult female offspring rats exposed to dexamethasone prenatally

Hao Kou, Shuxia Gui, Yongguo Dai, Yu Guo, Hui Wang

Toxicology and Applied Pharmacology

DOI

2020

Female-specific activation of pregnane X receptor mediates sex difference in fetal hepatotoxicity by prenatal monocrotaline exposure

Enfei Xiang, Qi Guo, Yongguo Dai, Xiaoxiang Sun, Jie Liu, Chengpeng Fan, Yanqing Wang, Shuaikai Qiu, Hui Wang, Yu Guo

Toxicology and Applied Pharmacology

DOI

2020

Prenatal ethanol exposure induced disorder of hypothalamic-pituitary-adrenal axis-associated neuroendocrine metabolic programming alteration and dysfunction of glucose and lipid metabolism in 40-week-old female offspring rats

Liping Xia, Zhexiao Jiao, Linguo Pei, Chao Yuan, Yanjuan Zhao, Yu Guo, Hui Wang

Reproductive Toxicology

DOI

2019

孕期外源物暴露致子代HPA轴改变的不良妊娠结局及远期危害

李芬，郭喻，廖丽娜，敖英，王芬

《医学综述》

2019

孕期咖啡因暴露致子代大鼠高脂饮食下胰腺形态和糖代谢功能改变

桂淑霞，寇皓，郭喻，吴东方，汪晖

《中国医院药学杂志》

DOI

2019

细胞色素P450氧化还原酶在发育中的作用

戴永国，赵艳娟，汪晖，郭喻

《武汉大学学报(医学版)》

DOI

2019

孕期野百合碱暴露对大鼠胎盘的损伤作用及其代谢机制

刘杰，杨晓静，郑江，王艳清，向娥，汪晖，郭喻

《中国药物警戒》

2019

孕期野百合碱暴露对胎鼠胆固醇水平的影响

郭麒，王艳清，程艳香，刘杰，邱帅凯，向娥，汪晖，郭喻

《中国药物警戒》

2019

吡咯里西啶生物碱毒性作用研究进展

孙潇翔，向娥，邱帅凯，汪晖，郭喻

《中国药物警戒》

2019

Sex difference in monocrotaline-induced developmental toxicity and fetal hepatotoxicity in rats

Jinyuan Luo, Xiaojing Yang, Shuaikai Qiu, Xia Li, Enfei Xiang, Yan Fang, Yanqing Wang, Li Zhang, Hui Wang, Jiang Zheng, Yu Guo

Toxicology

DOI

2019

Prenatal exposure to pyrrolizidine alkaloids induced hepatotoxicity and pulmonary injury in fetal rats

Yu Guo, Di Xiao, Xiaojing Yang, Jiang Zheng, Shuwei Hu, Panfeng Wu, Xiaoxia Li, Hao Kou, Hui Wang

Reproductive Toxicology

DOI

2019

Prenatal dexamethasone exposure-induced a gender-difference and sustainable multi-organ damage in offspring rats via serum metabolic profile analysis

Guanghui Chen, Hao Xiao, Jinzhi Zhang, Huizhen Zhang, Bin Li, Tao Jiang, Yajie Wen, Yimin Jiang, Kaili Fu, Dan Xu, Yu Guo, Ying Ao, Huichang Bi, Hui Wang

Toxicology Letters

DOI

2019

Age-Characteristic Changes of Glucose Metabolism, Pancreatic Morphology and Function in Male Offspring Rats Induced by Prenatal Ethanol Exposure

Di Xiao, Hao Kou, Shuxia Gui, Zhenyu Ji, Yu Guo, Yin Wu, Hui Wang

Frontiers in Endocrinology

DOI

2018

Low-expressional IGF1 mediated methimazole-induced liver developmental toxicity in fetal mice

Guihua Wang, Bo He, Wen Hu, Kexin Liu, Xiaohan Gong, Hao Kou, Yu Guo, Hui Wang

Toxicology

DOI

2018

Maternal-Fetal Disposition and Metabolism of Retrorsine in Pregnant Rats

Xia Li, Xiaojing Yang, Enfei Xiang, Jinyuan Luo, Shuaikai Qiu, Yan Fang, Li Zhang, Yu Guo, Jiang Zheng, Hui Wang

Drug Metabolism and Disposition

DOI

2018

Synergistic effects of prenatal nicotine exposure and post‐weaning high‐fat diet on hypercholesterolaemia in rat offspring of different sexes

Chunyan Zhu, Yu Guo, Hanwen Luo, Yimeng Wu, Jacques Magdalou, Liaobin Chen, Hui Wang

Basic & Clinical Pharmacology & Toxicology

DOI

2018

Two intrauterine programming mechanisms of adult hypercholesterolemia induced by prenatal nicotine exposure in male offspring rats

Jin Zhou, Chunyan Zhu, Hanwen Luo, Lang Shen, Jun Gong, Yimeng Wu, Jacques Magdalou, Liaobin Chen, Yu Guo, Hui Wang

The FASEB Journal

DOI

2017

孕期乙醇暴露所致高脂饮食子代大鼠糖代谢功能改变

李霞，肖笛，寇皓，张郦，纪振宇，郭喻，汪晖

《中国临床药理学与治疗学》

2017

阿魏酸钠对脂多糖引起小鼠早产和死胎的防治作用（英文）

李小军，马振国，郭喻，寇皓，孙荣则，纪振宇，汪晖

《中国药理学与毒理学杂志》

2017

Effects of prenatal caffeine exposure on glucose homeostasis of adult offspring rats

Hao Kou, Guihua Wang, Linguo Pei, Li Zhang, Chai Shi, Yu Guo, Dongfang Wu, Hui Wang

Die Naturwissenschaften

DOI

2017

Insulin-like Growth Factor 1 Mediates Adrenal Development Dysfunction in Offspring Rats Induced by Prenatal Food Restriction

Zheng He, Feng Lv, Yufeng Ding, Chunyan Zhu, Hegui Huang, Li Zhang, Yu Guo, Hui Wang

Archives of Medical Research

DOI

2017

Prenatal Food Restriction with Postweaning High-fat Diet Alters Glucose Metabolic Function in Adult Rat Offspring

Di Xiao, Hao Kou, Li Zhang, Yu Guo, Hui Wang

Archives of Medical Research

DOI

2016

孕期尼古丁暴露对高脂饮食子代大鼠糖代谢的影响

吴茵，汪晖，郭喻，肖笛，徐焱成

《公共卫生与预防医学》

2016

孕期尼古丁暴露所致成年雄性子代大鼠肝脏CYP同工酶及抗氧化酶变化

何靓，郭喻，李镜清，纪振宇，黄民，汪晖

《武汉大学学报(医学版)》

2015

孕期咖啡因暴露的雄性子代大鼠高脂饮食/慢性应激下糖代谢异常及胰岛素抵抗的发生

周瑾，寇皓，郭喻，张郦，汪晖

《中国药理学与毒理学杂志》

2015

Gender-specific increase in susceptibility to metabolic syndrome of offspring rats after prenatal caffeine exposure with post-weaning high-fat diet

Jing Li, Hanwen Luo, Yimeng Wu, Zheng He, Li Zhang, Yu Guo, Lu Ma, Jacques Magdalou, Liaobin Chen, Hui Wang

Toxicology and Applied Pharmacology

DOI

2015

Single nucleotide polymorphism of CYP3A4 intron 2 and its influence on CYP3A4 mRNA expression and liver enzymatic activity in human liver

Min Huang, Hanming Wang, Yu Guo, Jie Ping, Man Chen, Dan Xu, Hui Wang

Journal of Huazhong University of Science and Technology [Medical Sciences]

DOI

2014

长期摄入咖啡因对幼年大鼠神经内分泌代谢功能的影响

纪振宇，陈蓓迪，倪曲波，寇皓，郭喻，汪晖

《武汉大学学报(医学版)》

2013

糖尿病的胎儿起源及机制研究

纪振宇，郭喻，陈蓓迪，汪晖

《医学新知》

2013

Synergistic effects of pyrrolizidine alkaloids and lipopolysaccharide on preterm delivery and intrauterine fetal death in mice

Yu Guo, Zhen‐Guo Ma, Hao Kou, Rongze Sun, Hanxiao Yang, Charles Vincent Smith, Jiang Zheng, Hui Wang

Toxicology Letters

DOI

2012

Selective Expression of CYP2A13 in Human Pancreatic α-Islet Cells

Yu Guo, Liang-Ru Zhu, Gang Lǚ, Hui Wang, Jun‐Yan Hong

Drug Metabolism and Disposition

DOI

2012

Letter to the Editor

Hui Wang, Yu Guo, Xiao‐Qian Wu, Chun Zhang, Zhang‐Xiu Liao

Clinical and Experimental Pharmacology and Physiology

DOI

2012

Protective Effect of Sodium Ferulate on Acetaldehyde-Treated Precision-Cut Rat Liver Slices

Yu Guo, Xiaoqian Wu, Chun Zhang, Zhang‐Xiu Liao, Yong Wu, Hui Wang

Journal of Medicinal Food

DOI

2012

A Herbal Composition of Semen Hoveniae, Radix Puerariae, and Fructus Schisandrae Shows Potent Protective Effects on Acute Alcoholic Intoxication in Rodent Models

Jie Xiong, Yu Guo, Luyi Li, Hang Hu, Xin-lan Qu, Xi-zhen Sun, Sheng-hua Liu, Hui Wang

Evidence-based Complementary and Alternative Medicine

DOI

2011

血管紧张素Ⅱ受体1型和2型在胎组织中的分布及表达特征

孟巍，李小军，何文博，郭喻，汪晖

《武汉大学学报(医学版)》

2010

Effect of indole‐3‐carbinol on ethanol‐induced liver injury and acetaldehyde‐stimulated hepatic stellate cells activation using precision‐cut rat liver slices

Yu Guo, Xiao‐Qian Wu, Chun Zhang, Zhang‐Xiu Liao, Yong Wu, Zheng‐Yuan Xia, Hui Wang

Clinical and Experimental Pharmacology and Physiology

DOI

2010

Synergistic antifibrotic effect of verapamil and interferon-γ in rats: partially based on enhanced verapamil oral bioavailability

Dan Xu, Man Chen, Yu Guo, Gai Liang, Benjian Zhang, Jingquan Tan, Jacques Magdalou, Hui Wang

European Journal of Gastroenterology & Hepatology

DOI

2009

妊娠状态下大鼠肝脏外源物代谢功能的改变

郭喻，肖凤琴，王婷，汪晖，潘晓靓，李婧婷

《武汉大学学报(医学版)》

2008

醋氨酚所致精密肝切片损伤模型的建立及CYP2E1的调节作用

李婧婷，汪晖，潘晓靓，鄢友娥，郭喻，张本坚

《中国临床药理学与治疗学》

2007

人细胞色素P450同工酶探针底物特异性的研究进展

郭喻，汪晖

《中国药理学通报》

2007

ESTABLISHMENT OF RAT PRECISION‐CUT FIBROTIC LIVER SLICE TECHNIQUE AND ITS APPLICATION IN VERAPAMIL METABOLISM

Yu Guo, Hui Wang, Chun Zhang

Clinical and Experimental Pharmacology and Physiology

DOI

2006

人参和枳椇子对小鼠乙醇急性中毒保护作用及其机制研究

梁赅，詹莉，汪晖，郭喻，鄢友娥

《医学新知》

2005

精密肝切片中乙醛活化肝星状细胞模型的建立

武晓茜，汪晖，郭喻，廖长秀，吴勇

《中国临床药理学与治疗学》

2005

阿魏酸钠对乙醇损伤性大鼠肝切片的保护作用及机制

张春，汪晖，郭喻

《武汉大学学报(医学版)》

2004

大鼠肝纤维化精密切片技术的建立

郭喻，汪晖

《中国临床药理学与治疗学》

精选作品

期刊论文

孕期对乙酰氨基酚暴露致发育毒性及其机制研究进展

Prenatal acetaminophen exposure induces changes of placental morphology and function and its influencing factors

Embryonic exposure to prednisone induces bone developmental toxicity in zebrafish: Characteristics and molecular mechanisms

核受体在胎源性非酒精性脂肪肝病中的作用

Sperm miR‐142‐3p Reprogramming Mediates Paternal Pre‐Pregnancy Caffeine Exposure‐Induced Non‐Alcoholic Steatohepatitis in Male Offspring Rats

The characterization of developmental toxicity in fetal offspring induced by acetaminophen exposure during pregnancy

Prenatal acetaminophen exposure and the developing ovary: Time, dose, and course consequences for fetal mice

Glucocorticoids and intrauterine programming of nonalcoholic fatty liver disease

Prenatal exposure to acetaminophen at different doses, courses and time causes testicular dysplasia in offspring mice and its mechanism

Lactational retrorsine exposure changes maternal milk components and disturbs metabolism homeostasis of offspring rats

Prenatal exposure to corn oil, CMC-Na or DMSO affects physical development and multi-organ functions in fetal mice

Intrauterine developmental origin, programming mechanism, and prevention strategy of fetal‐originated hypercholesterolemia

Course-, dose-, and stage-dependent toxic effects of prenatal acetaminophen exposure on fetal long bone development

Prenatal ethanol exposure induces dynamic changes of expression and activity of hepatic cytochrome P450 isoforms in male rat offspring

Prenatal dexamethasone exposure induced pancreatic β-cell dysfunction and glucose intolerance of male offspring rats: Role of the epigenetic repression of ACE2

Prenatal smoke (Nicotine) exposure and offspring's metabolic disease susceptibility in adulthood

Developmental toxicity and programming alterations of multiple organs in offspring induced by medication during pregnancy

母乳成分改变影响子代脂肪肝发生的研究进展

Identification and validation of reference genes for RT-qPCR analysis in fetal rat pancreas

Prenatal Exposure to Retrorsine Induces Developmental Toxicity and Hepatotoxicity of Fetal Rats in a Sex-Dependent Manner: The Role of Pregnane X Receptor Activation

表观遗传修饰在胰腺β细胞分化和功能中的作用

Epigenetic repression of AT2 receptor is involved in β cell dysfunction and glucose intolerance of adult female offspring rats exposed to dexamethasone prenatally

Female-specific activation of pregnane X receptor mediates sex difference in fetal hepatotoxicity by prenatal monocrotaline exposure

Prenatal ethanol exposure induced disorder of hypothalamic-pituitary-adrenal axis-associated neuroendocrine metabolic programming alteration and dysfunction of glucose and lipid metabolism in 40-week-old female offspring rats

孕期外源物暴露致子代HPA轴改变的不良妊娠结局及远期危害

孕期咖啡因暴露致子代大鼠高脂饮食下胰腺形态和糖代谢功能改变

细胞色素P450氧化还原酶在发育中的作用

孕期野百合碱暴露对大鼠胎盘的损伤作用及其代谢机制

孕期野百合碱暴露对胎鼠胆固醇水平的影响

吡咯里西啶生物碱毒性作用研究进展

Sex difference in monocrotaline-induced developmental toxicity and fetal hepatotoxicity in rats

Prenatal exposure to pyrrolizidine alkaloids induced hepatotoxicity and pulmonary injury in fetal rats

Prenatal dexamethasone exposure-induced a gender-difference and sustainable multi-organ damage in offspring rats via serum metabolic profile analysis

Age-Characteristic Changes of Glucose Metabolism, Pancreatic Morphology and Function in Male Offspring Rats Induced by Prenatal Ethanol Exposure

Low-expressional IGF1 mediated methimazole-induced liver developmental toxicity in fetal mice

Maternal-Fetal Disposition and Metabolism of Retrorsine in Pregnant Rats

Synergistic effects of prenatal nicotine exposure and post‐weaning high‐fat diet on hypercholesterolaemia in rat offspring of different sexes

Two intrauterine programming mechanisms of adult hypercholesterolemia induced by prenatal nicotine exposure in male offspring rats

孕期乙醇暴露所致高脂饮食子代大鼠糖代谢功能改变

阿魏酸钠对脂多糖引起小鼠早产和死胎的防治作用（英文）

Effects of prenatal caffeine exposure on glucose homeostasis of adult offspring rats

Insulin-like Growth Factor 1 Mediates Adrenal Development Dysfunction in Offspring Rats Induced by Prenatal Food Restriction

Prenatal Food Restriction with Postweaning High-fat Diet Alters Glucose Metabolic Function in Adult Rat Offspring

孕期尼古丁暴露对高脂饮食子代大鼠糖代谢的影响

孕期尼古丁暴露所致成年雄性子代大鼠肝脏CYP同工酶及抗氧化酶变化

孕期咖啡因暴露的雄性子代大鼠高脂饮食/慢性应激下糖代谢异常及胰岛素抵抗的发生

Gender-specific increase in susceptibility to metabolic syndrome of offspring rats after prenatal caffeine exposure with post-weaning high-fat diet

Single nucleotide polymorphism of CYP3A4 intron 2 and its influence on CYP3A4 mRNA expression and liver enzymatic activity in human liver

长期摄入咖啡因对幼年大鼠神经内分泌代谢功能的影响

糖尿病的胎儿起源及机制研究

Synergistic effects of pyrrolizidine alkaloids and lipopolysaccharide on preterm delivery and intrauterine fetal death in mice

Selective Expression of CYP2A13 in Human Pancreatic α-Islet Cells

Letter to the Editor

Protective Effect of Sodium Ferulate on Acetaldehyde-Treated Precision-Cut Rat Liver Slices

A Herbal Composition of Semen Hoveniae, Radix Puerariae, and Fructus Schisandrae Shows Potent Protective Effects on Acute Alcoholic Intoxication in Rodent Models

血管紧张素Ⅱ受体1型和2型在胎组织中的分布及表达特征

Effect of indole‐3‐carbinol on ethanol‐induced liver injury and acetaldehyde‐stimulated hepatic stellate cells activation using precision‐cut rat liver slices

Synergistic antifibrotic effect of verapamil and interferon-γ in rats: partially based on enhanced verapamil oral bioavailability

妊娠状态下大鼠肝脏外源物代谢功能的改变

醋氨酚所致精密肝切片损伤模型的建立及CYP2E1的调节作用

人细胞色素P450同工酶探针底物特异性的研究进展

ESTABLISHMENT OF RAT PRECISION‐CUT FIBROTIC LIVER SLICE TECHNIQUE AND ITS APPLICATION IN VERAPAMIL METABOLISM

人参和枳椇子对小鼠乙醇急性中毒保护作用及其机制研究

精密肝切片中乙醛活化肝星状细胞模型的建立

阿魏酸钠对乙醇损伤性大鼠肝切片的保护作用及机制

大鼠肝纤维化精密切片技术的建立

会议论文

基于多组学分析探究强的松龙暴露所致斑马鱼整体和多器官发育毒性特征及其共性靶标

孕烷X受体在中药单体吡咯里西啶生物碱毒性中的作用

哺乳期倒千里光碱暴露致成年子代脂肪肝的机制研究

吡咯里西啶生物碱毒性作用研究

哺乳期倒千里光碱暴露致成年子代脂肪肝及其机制研究

哺乳期母体倒千里光碱暴露诱导母乳成分及子代大鼠糖脂代谢稳态改变

孕期地塞米松暴露所致雄性子代大鼠肝脏CYP3A表达编程改变及其机制

吡咯里西啶生物碱的发育毒性及其代谢特征

吡咯西啶双烷生物碱所致的胎儿发育毒性研究

阿魏酸钠对脂多糖所致早产及胎儿死亡的保护作用及其机制研究

CYP2A13在胎儿各器官中的表达差异