渠志倍｜复旦大学｜学者主页

期刊论文

2026

Discovery of a Covalent Inhibitor Targeting the PHGDH Dimer Interface with Antitumor Efficacy

Lei Feng, Liu Y, Yiwei Zhang, Zhongjiao Fan, Xinyuan Wu, Xiancheng Yang, Leyi Liu, Zhibei Qu, Ye Shen, Xiaojie Lu, Lu Zhou

Journal of Medicinal Chemistry

DOI

2026

Discovery of 1-(Azetidin-3-ylmethyl)-1 H -benzo[ d ]imidazole Derivatives as Efficient GSTP1 Inhibitors for Gastric Cancer Treatment via Warhead Removal Strategy

Wenhao Xie, Yuehong Chen, Lulu Jiang, Xinyuan Wu, Zhiyuan Qi, Tianbai Shuai, Mingzhong Yang, Zhiyang Wang, Jinghan Gao, Yingjie Zhu, Xiaojie Lu, Meng-Lin Huang, Zhibei Qu, Wenfu Tan, Jian Ding, Lu Zhou

Journal of Medicinal Chemistry

DOI

2026

Accelerated CRISPR/Cas12a‐Based Point‐of‐Care Diagnostics Through Critical Coupling Distance Control

Tong Su, Dan Zhu, Xiaojian Li, Zhibei Qu, Feng Li, Dongming Zhao, Guoqing Shao, Zhixin Feng, Shao Su, Jie Chao, Xiaolei Zuo, Chunhai Fan, Lianhui Wang

Advanced Materials

DOI

2026

Electronic structure guided design of a cysteine-reactive electrochemical probe for in vivo brain analysis

Huihui Wang, Zhibei Qu, Cong Luo, Yijia Liu, Hui Pan, Zhaolun Duan, Qian Wang, Haoyue Xiang, Hui Cheng Gu

Chinese Chemical Letters

DOI

2025

Expanding the Chemistry of Acyl Diazo Electrophile as a Tunable Warhead for Covalent Targeting of KRAS (G12D) Mutant

Tianbai Shuai, Rong Zhang, Zi-Hang Yuan, Mingya Zhang, Zhongjiao Fan, Xiaoxue Ruan, Zhiyuan Qi, Wenhao Xie, Ping Liu, Motonari Uesugi, Qing Li, Zhibei Qu, Minjia Tan, Hua Su, Lu Zhou

Journal of Medicinal Chemistry

DOI

2025

Gravity-induced tunable asymmetric droplet splitting for flexible and precise reagent formulation on vertical digital microfluidic devices

Juyue Dong, Zerui Song, Kunlun Guo, Hang Xu, Zhibei Qu, Zhen Gu, Huifeng Wang

Lab on a Chip

DOI

2025

Thiophosphoryl pyridinol/pyrimidinol-based probes for covalent and fluorescent sensing of intracellular Cu2+

Zhiyuan Qi, Jing Chen, Wenhao Xie, Zhibei Qu, Motonari Uesugi, Lu Zhou

Chinese Chemical Letters

DOI

2025

Pioneering Biomedical Applications with Intelligent Engineering

Zhibei Qu, Tao Sun, Lu Zhou

Small Methods

DOI

2024

基于类器官芯片的药物筛选及其中的生物化学原理

渠志倍，王昌鑫，醴磊，李佳泽，张骏

《大学化学》

2024

Discovery of a novel thiophene carboxamide analogue as a highly potent and selective sphingomyelin synthase 2 inhibitor for dry eye disease therapy

Jintong Yang, Yiteng Lu, Kexin Hu, Xinchen Zhang, Wei Wang, Deyong Ye, Mingguang Mo, Xin Xiao, Xichen Wan, Yuqing Wu, Shuxian Zhang, He Huang, Zhibei Qu, Yimin Hu, Yu Cao, Jiaxu Hong, Lu Zhou

Acta Pharmaceutica Sinica B

DOI

2023

ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries

Lulu Jiang, Sixiu Liu, Xinglong Jia, Qinting Gong, Xin Wen, Weiwei Lu, Jintong Yang, Xinyuan Wu, Xuan Wang, Yanrui Suo, Yilin Li, Motonari Uesugi, Zhibei Qu, Minjia Tan, Xiaojie Lu, Lu Zhou

Journal of the American Chemical Society

DOI

2023

Organoid-on-a-Chip for Drug Screening and the Inherent Biochemistry Principles

Zhibei Qu, Changxin Wang, Lei Li, Jia-Ze Li, Jun Zhang

Daxue Huaxue

DOI

2022

Phase transferring luminescent gold nanoclusters via single-stranded DNA

Yu Li, Hui Lu, Zhibei Qu, Mingqiang Li, Haoran Zheng, Peilin Gu, Jiye Shi, Jiang Li, Qian Li, Lihua Wang, Jing Chen, Chunhai Fan, Jianlei Shen

Science China Chemistry

2022

Benzo[d]isoxazole Derivatives as Hypoxia-Inducible Factor (HIF)-1α Inhibitors

Zian Xue, Huiti Li, Wenhao Xie, Ying Xu, Lu Zhou, Zhibei Qu

ACS Medicinal Chemistry Letters

DOI

书籍章节

2022

Drug Development in the Field of Sphinogolipid Metabolism

Zhibei Qu, Lu Zhou

Advances in experimental medicine and biology

DOI

渠志倍

精选作品

期刊论文

Discovery of a Covalent Inhibitor Targeting the PHGDH Dimer Interface with Antitumor Efficacy

Discovery of 1-(Azetidin-3-ylmethyl)-1 H -benzo[ d ]imidazole Derivatives as Efficient GSTP1 Inhibitors for Gastric Cancer Treatment via Warhead Removal Strategy

Accelerated CRISPR/Cas12a‐Based Point‐of‐Care Diagnostics Through Critical Coupling Distance Control

Electronic structure guided design of a cysteine-reactive electrochemical probe for in vivo brain analysis

Expanding the Chemistry of Acyl Diazo Electrophile as a Tunable Warhead for Covalent Targeting of KRAS (G12D) Mutant

Gravity-induced tunable asymmetric droplet splitting for flexible and precise reagent formulation on vertical digital microfluidic devices

Thiophosphoryl pyridinol/pyrimidinol-based probes for covalent and fluorescent sensing of intracellular Cu2+

Pioneering Biomedical Applications with Intelligent Engineering

基于类器官芯片的药物筛选及其中的生物化学原理

Discovery of a novel thiophene carboxamide analogue as a highly potent and selective sphingomyelin synthase 2 inhibitor for dry eye disease therapy

ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries

Organoid-on-a-Chip for Drug Screening and the Inherent Biochemistry Principles

Phase transferring luminescent gold nanoclusters via single-stranded DNA

Benzo[d]isoxazole Derivatives as Hypoxia-Inducible Factor (HIF)-1α Inhibitors

书籍章节

Drug Development in the Field of Sphinogolipid Metabolism

研究方向