黄茂华｜暨南大学｜学者主页

2026

周细胞NNMT构建免疫逃逸血管龛限制肿瘤免疫治疗疗效（英文）

王生，叶格妮，张彩云，谭霖，张章，徐曦，陈鑫辉，张益铭，徐小玲，潘京华，蓝彤，张君秋，林昌伟，黄丹丹，李啸波，袁霞，陈敏锋，王晨然，叶文才，张冬梅，黄茂华

Science Bulletin

2026

Targeting FAPα-positive hepatic stellate cells ameliorates the formation of pre-metastatic niche

Sishan Yan, Jingwen Xie, Lijuan Deng, Chulong Chen, Wenfeng Mai, Shuran Fan, Runyu Liu, Maohua Huang, Xiaobo Li, Junqiu zhang, Shuai Han, Zhongshun Tang, Wenqian Yin, Qun Miao, Chunlin Fan, Wencai Ye, Changzheng Shi, Dongmei Zhang, Ming Qi, Minfeng Chen

Acta Pharmaceutica Sinica B

精选作品

期刊论文

周细胞NNMT构建免疫逃逸血管龛限制肿瘤免疫治疗疗效（英文）

Targeting FAPα-positive hepatic stellate cells ameliorates the formation of pre-metastatic niche

In vitro and in vivo antiangiogenic activity of desacetylvinblastine monohydrazide through inhibition of VEGFR2 and Axl pathways: Am J Cancer Res. 2016; 6(4): 843-858

Pericyte NNMT drives an immune-hostile vascular niche and restricts cancer immunotherapy

Targeting TCF21-TCF3 heterodimer in tumor-associated pericytes attenuates hematogenous metastasis by restoring pericyte gatekeeper function

癌症相关ENO2通过介导组蛋白乳酸化诱导M2型巨噬细胞极化促进头颈部鳞状细胞癌的转移（英文）

Pericytes promote metastasis by regulating tumor local vascular tone and hemodynamics

Pericyte drives the formation of circulating tumour cell-neutrophil clusters to promote colorectal cancer metastasis

Cancer ENO2 Induces Histone Lactylation-Mediated M2 Macrophage Polarization and Facilitates Metastasis of Head and Neck Squamous Cell Carcinoma

Targeting FAPα-positive lymph node metastatic tumor cells suppresses colorectal cancer metastasis

Vascular Pericyte-Derived Exosomes Inhibit Bone Resorption via Traf3

ENO2-derived phosphoenolpyruvate functions as an endogenous inhibitor of HDAC1 and confers resistance to antiangiogenic therapy

TCAF2 in Pericytes Promotes Colorectal Cancer Liver Metastasis via Inhibiting Cold‐Sensing TRPM8 Channel

lncRNA SYTL5-OT4 promotes vessel co-option by inhibiting the autophagic degradation of ASCT2

Author correction to “The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway” [Acta Pharm Sin B 12 (2022) 1288–1304]

Erratum: In vitro and in vivo antiangiogenic activity of desacetylvinblastine monohydrazide through inhibition of VEGFR2 and Axl pathways.

Novel TCF21 high pericyte subpopulation promotes colorectal cancer metastasis by remodelling perivascular matrix

Targeting FAPα-expressing hepatic stellate cells overcomes resistance to antiangiogenics in colorectal cancer liver metastasis models

New insights into antiangiogenic therapy resistance in cancer: Mechanisms and therapeutic aspects

New Insights Into the Regulatory Roles of Extracellular Vesicles in Tumor Angiogenesis and Their Clinical Implications

Tumor perivascular cell-derived extracellular vesicles promote angiogenesis via the Gas6/Axl pathway

The FAP -activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway

Perivascular cell‐derived extracellular vesicles stimulate colorectal cancer revascularization after withdrawal of antiangiogenic drugs

Targeting FAPα-expressing tumor-associated mesenchymal stromal cells inhibits triple-negative breast cancer pulmonary metastasis

A vascular disrupting agent overcomes tumor multidrug resistance by skewing macrophage polarity toward the M1 phenotype

Desacetylvinblastine Monohydrazide Disrupts Tumor Vessels by Promoting VE-cadherin Internalization

Pericyte-targeting prodrug overcomes tumor resistance to vascular disrupting agents

Luteolin inhibits angiogenesis by blocking Gas6/Axl signaling pathway

Fibroblast Activation Protein α Activated Tripeptide Bufadienolide Antitumor Prodrug with Reduced Cardiotoxicity

In vitro and in vivo antiangiogenic activity of desacetylvinblastine monohydrazide through inhibition of VEGFR2 and Axl pathways.

书籍章节

VEGFR Inhibitors as Sensitizing Agents for Cancer Chemotherapy

研究方向