邓永键｜南方医科大学｜学者主页

2025

A fully automated quantitative analysis method based on deep learning algorithms for immunohistochemical staining expression intensities

Yongjian Deng, Bojun Cai, Xiaomei Wang

Intelligent Oncology

2025

Longitudinal assessment of automated gray-white matter ratio for outcome prediction after cardiac arrest

Min Wu, Weiwei Liu, Sheng Kuang, Jiajia Zhou, Xujian He, Jia Hu, Yongjian Deng, Hui-Yin Lin, Jie Zhang, Chen-Yang Zhao, Meiqi Zeng, Hanxiao Wang, Meng Wu, Wang-Xiao Bao, Tong Li, Ben-Yan Luo, Kang Wang

Critical Care

DOI

2025

The biomarker and clinical changes across the Alzheimer’s continuum study (BCAS): rationale, design, and baseline characteristics of the first 1,013 participants

Hui Chen, Hong-Yan Dai, Li Zhang, Yongjian Deng, Kan Zhang, Jie Yu, Guo-Ping Peng, Ze-Xin Guo, Jing Zhang, Chang-Zheng Yuan, Fang Xie, Ben-Yan Luo

Alzheimer's Research & Therapy

DOI

2024

Interferon-γ in the tumor microenvironment promotes the expression of B7H4 in colorectal cancer cells, thereby inhibiting cytotoxic T cells

Zhi-Liang Jing, Guang‐long Liu, Na Zhou, Dong-Yan Xu, Na Feng, Yan Lei, Lili Ma, Minshan Tang, Guihui Tong, Na Tang, Yong‐Jian Deng

Scientific Reports

DOI

2024

AGTR1: a potential biomarker associated with the occurrence and prognosis of lung adenocarcinoma

Rui Xiao, Jia-Jia Han, Yongjian Deng, Ling Zhang, Y. Qian, N. Tian, Zhen Yang, Lin Zhang

Frontiers in Oncology

DOI

2023

Echocardiography-based machine learning algorithm for distinguishing ischemic cardiomyopathy from dilated cardiomyopathy

Mei Zhou, Yongjian Deng, Yi Liu, Xiaolin Su, Xiao-Cong Zeng

BMC Cardiovascular Disorders

DOI

2022

肝脏炎性假瘤样滤泡树突状细胞肉瘤1例

杨红军，邓永键

《临床与实验病理学杂志》

2022

结直肠癌离心性表达Cdc42伴E-cadherin缺失的预后分析

罗金风，刘广龙，徐东艳，李小清，邓永键

《临床与实验病理学杂志》

2022

MIF/SCL3A2 depletion inhibits the proliferation and metastasis of colorectal cancer cells via the AKT/GSK‐3β pathway and cell iron death

Guan Huang, Lili Ma, Lan Shen, Yan Lei, Lili Guo, Yongjian Deng, Yanqing Ding

Journal of Cellular and Molecular Medicine

DOI

2020

Cdc42 subcellular relocation in response to VEGF/NRP1 engagement is associated with the poor prognosis of colorectal cancer

Lili Ma, Lili Guo, Yang Luo, Guang-long Liu, Lei Yan, Fangyan Jing, Yunli Zhang, Guihui Tong, Zhi-Liang Jing, Lan Shen, Minshan Tang, Yanqing Ding, Yong‐Jian Deng

Cell Death and Disease

DOI

2019

手术切除的结直肠癌组织中的肿瘤干细胞的培养及鉴定

唐娜，周略，成志强，邓永键，丁彦青

《南方医科大学学报》

2019

High expression of PRKDC promotes breast cancer cell growth via p38 MAPK signaling and is associated with poor survival

Yan Zhang, Weikang Yang, Guoming Wen, Hongping Tang, Chuan‐An Wu, Yanxia Wu, Zhi-Liang Jing, Minshan Tang, Guang‐long Liu, Da‐zhou Li, Yanhua Li, Yong‐Jian Deng

Molecular Genetics & Genomic Medicine

DOI

2019

PRKDC is a prognostic marker for poor survival in gastric cancer patients and regulates DNA damage response

Yan Zhang, Guoming Wen, Chuan‐An Wu, Zhi-Liang Jing, Dazhou Li, Guang‐long Liu, Xu-Xuan Wei, Minshan Tang, Yànhuá Lǐ, Yan Zhong, Yong‐Jian Deng, Weikang Yang

Pathology - Research and Practice

DOI

2019

[Culture and identification of tumor stem cells from surgically resected colorectal cancer tissues].

Na Tang, Lue Zhou, Zhiqiang Cheng, Yong‐Jian Deng, Yanqing Ding

PubMed

DOI

2018

ERp29 counteracts the suppression of malignancy mediated by endoplasmic reticulum stress and promotes the metastasis of colorectal cancer

Lili Guo, Lili Ma, Chao Liu, Lei Yan, Na Tang, Yingxin Huang, Guan J. Huang, Dazhou Li, Qi Wang, Guanglong Liu, Minshan Tang, Zhi-Liang Jing, Yong‐Jian Deng

Oncology Reports

DOI

2017

Prohibitin, relocated to the front ends, can control the migration directionality of colorectal cancer cells

Lili Ma, Lan Shen, Guihui Tong, Na Tang, Yang Luo, Lili Guo, Chun-Ting Hu, Ying-Xin Huang, Guan J. Huang, Fangyan Jing, Chao Liu, Zhuo-Yi Li, Na Zhou, Qian-Wen Yan, Lei Yan, Shijie Zhu, Zhiqiang Cheng, Guangwen Cao, Yong‐Jian Deng, Yanqing Ding

Oncotarget

DOI

2015

鼠源性结肠癌细胞CT26.WT对树突状细胞抗原递呈的细胞免疫抑制

冯娜，周娜，邓永键

《实用医学杂志》

2015

MIF, secreted by human hepatic sinusoidal endothelial cells, promotes chemotaxis and outgrowth of colorectal cancer in liver prometastasis

Chun-Ting Hu, Lili Guo, Na Feng, Lei Zhang, Na Zhou, Lili Ma, Lan Shen, Guihui Tong, Qian-Wen Yan, Shijie Zhu, Xiu‐Wu Bian, Maode Lai, Yong‐Jian Deng, Yanqing Ding

Oncotarget

DOI

2014

伴脂肪瘤分化室管膜瘤1例临床病理分析

赵海燕，张彦，邓永键，刘巍，黄冠，韩慧霞

《临床与实验病理学杂志》

2014

Overexpression of Tiam1 is associated with malignant phenotypes of nasopharyngeal carcinoma

Yi� Ding, Bin Chen, Jing Huang, Wenli Zhang, Hongjun Yang, Yong‐Jian Deng, Jie Lin, Shuang Wang, Xiangmei Zhang

Oncology Reports

DOI

2014

Metastatic cancer stem cells: from the concept to therapeutics.

Wenting Liao, Yaping Ye, Yong‐Jian Deng, Xiu‐Wu Bian, Yan-qing Ding

PubMed

2013

内淋巴囊肿瘤1例临床病理学观察

杨红军，邓永键，丁彦青

《临床与实验病理学杂志》

2012

简易的单个肿瘤干细胞分离及其培养方法

邓永键，蒋强，于莉娜，王红霞，胡纯婷，刘超，丁彦青

《南方医科大学学报》

2011

结直肠癌转移相关基因PCR芯片的建立及初步应用

肖小琴，唐娜，刘超，王红霞，蒋强，邓永键，丁彦青

《南方医科大学学报》

2011

FMNL2 is a positive regulator of cell motility and metastasis in colorectal carcinoma

Xi‐ling Zhu, Yuan‐feng Zeng, Jian Guan, Yufa Li, Yong‐Jian Deng, Xiu‐Wu Bian, Yanqing Ding, Liang Li

The Journal of Pathology

DOI

2011

Methylation status of T-lymphoma invasion and metastasis 1 promoter and its overexpression in colorectal cancer

Jin He, Tingting Li, Yi� Ding, Yi� Ding, Yong‐Jian Deng, Wenli Zhang, Hongjun Yang, Jie Zhou, Chao Liu, Jie Lin, Yanqing Ding, Yanqing Ding

Human Pathology

DOI

2011

HOXB7 as a Prognostic Factor and Mediator of Colorectal Cancer Progression

Wenting Liao, Dan Jiang, Jian Yuan, Yanmei Cui, Xiwen Shi, Cui-Min Chen, Xiu‐Wu Bian, Yongjian Deng, Yanqing Ding

Clinical Cancer Research

DOI

2010

LUNX基因增强子的克隆及调控活性分析

邓永键，王爽，郑林，唐娜，肖小琴

《南方医科大学学报》

2010

[Cloning of human LUNX gene enhancers and analysis of transcriptional regulation].

Yong‐Jian Deng, Shuang Wang, Zheng Lin, Na Tang, Xiaoqin Xiao

PubMed

2010

CD133+ single cell-derived progenies of colorectal cancer cell line SW480 with different invasive and metastatic potential

Guangqiu Li, Chao Liu, Jian Yuan, Xiaoqin Xiao, Na Tang, Junmei Hao, Hongwei Wang, Xiuwu Bian, Yong‐Jian Deng, Yanqing Ding

Clinical & Experimental Metastasis

DOI

2009

肿瘤转移干细胞与抗转移策略

邓永键，丁彦青

《中国肿瘤生物治疗杂志》

2009

横纹肌样脑膜瘤的诊断与鉴别诊断

韩慧霞，杜平，张彦，邓永键

《中国肿瘤临床》

2009

大肠癌247例临床病理特征分析

刘瑾，丁彦青，邓永键，郑普生，胡桂周

《实用医学杂志》

2009

CD133+结直肠癌SW480细胞系克隆亚系的建立

李广秋，刘超，郝俊梅，李建明，邓永键，丁彦青

《诊断病理学杂志》

2009

Transgelin as a suppressor is associated with poor prognosis in colorectal carcinoma patients

Liang Zhao, Hui Wang, Yong‐Jian Deng, Shuang Wang, Chao Liu, Jin He, Yanqing Ding

Modern Pathology

DOI

2008

复发性弥漫性大B细胞淋巴瘤经美罗华联合化疗治疗后CD20表达缺失1例报道并文献复习

周新华，赵彤，邓永键，丁彦青

《南方医科大学学报》

2008

Serum proteome analysis for profiling protein markers associated with carcinogenesis and lymph node metastasis in nasopharyngeal carcinoma

Qiulin Liao, Liang Zhao, Xiaodong Chen, Yongjian Deng, Yan-qing Ding

Clinical & Experimental Metastasis

DOI

2007

可视化观察Tiam-1基因沉默对人大肠癌细胞株SW480转移的影响

陈娟芝，邓永键，谢思明，丁彦青

《南方医科大学学报》

2007

额顶部头皮内上皮样肉瘤一例

杨磊，丁彦青，赵彤，邓永键

《中华病理学杂志》

2007

多中心性网状组织细胞增生症临床病理特征

杨红军，丁彦青，邓永键，蔡俊杰

《广东医学》

2004

泛发性发疹性组织细胞瘤一例

邓永键，郝飞，周春丽，孙仁山，向明明，王继文，钟白玉，叶庆佾，刘荣卿

《中华皮肤科杂志》

2002

颅咽管瘤增殖细胞核抗原表达与肿瘤复发的关系

潘军，漆松涛，邓永键，丁彦青，彭林，李晓强

《南方医科大学学报》

1999

CD44v6对实验性大肠癌肝转移的影响

李祖国，丁彦青，邓永键，朱梅刚

《中国肿瘤临床》

1998

CD44V6的表达对大肠癌细胞骨架的影响

李祖国，丁彦青，邓永键，朱梅刚

《中华病理学杂志》

1998

CD44V6在大肠癌转移中作用机理的研究

李祖国，丁彦青，邓永键，郭君其，朱梅刚

《中华医学杂志》

1998

E-cadherin对人大肠癌细胞株浸润行为的影响

邓永键，邱红明，黄卓垣，李祖国

《现代消化及介入诊疗》

1998

CD44V6的表达对大肠癌细胞缝隙连接细胞间通讯的影响

李祖国，丁彦青，邓永键

《解放军医学杂志》

1998

大肠癌细胞缝隙连接细胞间通讯功能与大肠癌转移相关性研究

李祖国，丁彦青，邓永键

《解放军医学杂志》

1998

Comparison of metastatic potentiality and features related to metastasis in human colorectal carcinoma cell lines

邓永键，李祖国，邱红明，黄卓垣，丁彦青，朱梅刚

Military Medical Research

1998

Quantitative investigation of invasive effects of laminin-receptor antibodies on human colorectal carcinoma cell lines

邓永键，邱红明，李祖国，黄卓垣，丁彦青

Military Medical Research

1998

大肠癌细胞株浸润人羊膜时Ⅳ型胶原酶表达的影响因素

邓永键，黄卓垣，邱红明

《临床与实验病理学杂志》

1998

CD44V6在不同转移能力人大肠癌细胞系中的表达

李祖国，丁彦青，邓永键，朱梅刚

《临床与实验病理学杂志》

精选作品

期刊论文

A fully automated quantitative analysis method based on deep learning algorithms for immunohistochemical staining expression intensities

Longitudinal assessment of automated gray-white matter ratio for outcome prediction after cardiac arrest

The biomarker and clinical changes across the Alzheimer’s continuum study (BCAS): rationale, design, and baseline characteristics of the first 1,013 participants

Interferon-γ in the tumor microenvironment promotes the expression of B7H4 in colorectal cancer cells, thereby inhibiting cytotoxic T cells

AGTR1: a potential biomarker associated with the occurrence and prognosis of lung adenocarcinoma

Echocardiography-based machine learning algorithm for distinguishing ischemic cardiomyopathy from dilated cardiomyopathy

肝脏炎性假瘤样滤泡树突状细胞肉瘤1例

结直肠癌离心性表达Cdc42伴E-cadherin缺失的预后分析

MIF/SCL3A2 depletion inhibits the proliferation and metastasis of colorectal cancer cells via the AKT/GSK‐3β pathway and cell iron death

Cdc42 subcellular relocation in response to VEGF/NRP1 engagement is associated with the poor prognosis of colorectal cancer

手术切除的结直肠癌组织中的肿瘤干细胞的培养及鉴定

High expression of PRKDC promotes breast cancer cell growth via p38 MAPK signaling and is associated with poor survival

PRKDC is a prognostic marker for poor survival in gastric cancer patients and regulates DNA damage response

[Culture and identification of tumor stem cells from surgically resected colorectal cancer tissues].

ERp29 counteracts the suppression of malignancy mediated by endoplasmic reticulum stress and promotes the metastasis of colorectal cancer

Prohibitin, relocated to the front ends, can control the migration directionality of colorectal cancer cells

鼠源性结肠癌细胞CT26.WT对树突状细胞抗原递呈的细胞免疫抑制

MIF, secreted by human hepatic sinusoidal endothelial cells, promotes chemotaxis and outgrowth of colorectal cancer in liver prometastasis

伴脂肪瘤分化室管膜瘤1例临床病理分析

Overexpression of Tiam1 is associated with malignant phenotypes of nasopharyngeal carcinoma

Metastatic cancer stem cells: from the concept to therapeutics.

内淋巴囊肿瘤1例临床病理学观察

简易的单个肿瘤干细胞分离及其培养方法

结直肠癌转移相关基因PCR芯片的建立及初步应用

FMNL2 is a positive regulator of cell motility and metastasis in colorectal carcinoma

Methylation status of T-lymphoma invasion and metastasis 1 promoter and its overexpression in colorectal cancer

HOXB7 as a Prognostic Factor and Mediator of Colorectal Cancer Progression

LUNX基因增强子的克隆及调控活性分析

[Cloning of human LUNX gene enhancers and analysis of transcriptional regulation].

CD133+ single cell-derived progenies of colorectal cancer cell line SW480 with different invasive and metastatic potential

肿瘤转移干细胞与抗转移策略

横纹肌样脑膜瘤的诊断与鉴别诊断

大肠癌247例临床病理特征分析

CD133+结直肠癌SW480细胞系克隆亚系的建立

Transgelin as a suppressor is associated with poor prognosis in colorectal carcinoma patients

复发性弥漫性大B细胞淋巴瘤经美罗华联合化疗治疗后CD20表达缺失1例报道并文献复习

Serum proteome analysis for profiling protein markers associated with carcinogenesis and lymph node metastasis in nasopharyngeal carcinoma

可视化观察Tiam-1基因沉默对人大肠癌细胞株SW480转移的影响

额顶部头皮内上皮样肉瘤一例

多中心性网状组织细胞增生症临床病理特征

泛发性发疹性组织细胞瘤一例

颅咽管瘤增殖细胞核抗原表达与肿瘤复发的关系

CD44v6对实验性大肠癌肝转移的影响

CD44V6的表达对大肠癌细胞骨架的影响

CD44V6在大肠癌转移中作用机理的研究

E-cadherin对人大肠癌细胞株浸润行为的影响

CD44V6的表达对大肠癌细胞缝隙连接细胞间通讯的影响

大肠癌细胞缝隙连接细胞间通讯功能与大肠癌转移相关性研究

Comparison of metastatic potentiality and features related to metastasis in human colorectal carcinoma cell lines

Quantitative investigation of invasive effects of laminin-receptor antibodies on human colorectal carcinoma cell lines

大肠癌细胞株浸润人羊膜时Ⅳ型胶原酶表达的影响因素

CD44V6在不同转移能力人大肠癌细胞系中的表达

会议论文

高频超声检查评分在鉴别乳腺实性占位良恶性中的价值

预印本

Cdc42 Mediates the VEGF/NRP1 Axis to Assemble Leading Edge of Colorectal Cancer Cells for Guiding Migration

研究方向