郑良玉

2026

A simple and efficient biodegradation route for nitroaromatic compounds using a nitroreductase from Bacillus subtilis and its "cell-like" immobilized form.

Journal of Biotechnology

DOI

2026

Construction of a Pickering emulsion system of ω-transaminase from Bacillus megaterium and its application in the continuous synthesis of chiral lactam.

International Journal of Biological Macromolecules

DOI

2025

Engineering a non-naturally enantioselective carbonyl reduction of diaryl α-keto amides by an “ene”-reductase from Bacillus subtilis and its mutant enzymes

Molecular Catalysis

DOI

2025

Stereoselective preparation of chiral benzo-γ-lactam by ω-transaminase variants and their immobilized forms using protein crystal as a scaffold.

International Journal of Biological Macromolecules

DOI

2025

Structure-guided evolution to improve the catalytic performance of aldo-keto reductase yhdN from Bacillus subtilis for preparing chiral diaryl α-hydroxy amides.

International Journal of Biological Macromolecules

DOI

2025

Engineering silica nanocoated whole-cell asymmetric biocatalyst for efficient preparation of a key chiral intermediate of (S)-Rivastigmine.

Journal of Biotechnology

DOI

2024

Achieving cinnamic acid amides in water by a variant of acyltransferase from Mycobacterium smegmatis and its immobilized form using Ni-NTA modified aspen powder as a carrier.

International Journal of Biological Macromolecules

DOI

2023

Semi-rational engineering an aldo–keto reductase for stereocomplementary reduction of α-keto amide compounds

Microbial Cell Factories

DOI

2023

Highly efficient synthesis of chiral lactams by using a ω-transaminase from Bacillus megaterium and its mutant enzymes

Molecular Catalysis

DOI

2022

Engineering silica encapsulated composite of acyltransferase from Mycobacterium smegmatis and MIL-88A: A stability-and activity-improved biocatalyst for N-acylation reactions in water

Colloids and Surfaces B Biointerfaces

DOI

2022

Engineering the simply asymmetric Morita–Baylis–Hillman reactions in a sodium phosphate buffer system: from enzyme‐ to proline‐catalyzed transformation

Journal of Chemical Technology & Biotechnology

DOI

2021

Engineering actively magnetic crosslinked inclusion bodies of Candida antarctica lipase B: An efficient and stable biocatalyst for enzyme-catalyzed reactions

Molecular Catalysis

DOI

2021

Asymmetric Synthesis of Spiro[3,2′-morpholine-oxindoles] Derivatives via the [5 + 1] Annulation Reaction

The Journal of Organic Chemistry

DOI

2021

Imidodiphosphoric Acids Catalysed Asymmetric Functionaliza‐tion with Thiols: Access to Oxindole Derived ɑ‐Chiral Thioethers

Advanced Synthesis & Catalysis

DOI

2020

Soluble expression and biomimetic immobilization of a ω-transaminase from Bacillus subtilis: Development of an efficient and recyclable biocatalyst

Biochemical Engineering Journal

DOI

2019

Rational enhancement of enzyme-catalyzed enantioselective reaction by construction of recombinant enzymes based on additive strategy

Bioprocess and Biosystems Engineering

DOI

2019

Functionalized Poplar Powder as a Support Material for Immobilization of Enoate Reductase and a Cofactor Regeneration System

Journal of Microbiology and Biotechnology

DOI

2019

Directly covalent immobilization of Candida antarctica lipase B on oxidized aspen powder by introducing poly‑lysines: An economical approach to improve enzyme performance

International Journal of Biological Macromolecules

DOI

2018

Stereoselective synthesis of a key chiral intermediate of (S)-Rivastigmine by AKR-GDH recombinant whole cells

Journal of Biotechnology

DOI

2017

Co-immobilization of enoate reductase with a cofactor-recycling partner enzyme

Enzyme and Microbial Technology

DOI

2017

Simultaneously achieve soluble expression and biomimetic immobilization of Candida antarctica lipase B by introducing polyamine tags

Journal of Biotechnology

DOI

2016

Enzyme-Catalyzed Henry Reaction in Choline Chloride-Based Deep Eutectic Solvents

Journal of Microbiology and Biotechnology

DOI

2016

ChemInform Abstract: Chiral Imidodiphosphoric Acids‐Catalyzed Friedel—Crafts Reactions of Indoles/Pyrroles with 3‐Hydroxy‐indolyloxindoles: Enantioselective Synthesis of 3,3‐Diaryloxindoles.

ChemInform

DOI

2016

Chiral Imidodiphosphoric Acids‐Catalyzed Friedel–Crafts Reactions of Indoles/Pyrroles with 3‐Hydroxy‐indolyloxindoles: Enantioselective Synthesis of 3,3‐Diaryloxindoles

Advanced Synthesis & Catalysis

DOI

2015

First Novozym 435 lipase-catalyzed Morita–Baylis–Hillman reaction in the presence of amides

Enzyme and Microbial Technology

DOI

2015

ChemInform Abstract: H8‐BINOL Chiral Imidodiphosphoric Acids Catalyzed Cyclization Reactions of β,γ‐Unsaturated α‐Ketoesters, Arylamines and 1,3‐Dicarbonyl Compounds: Enantioselective Synthesis of 1,4‐Dihydropyridines.

ChemInform

DOI

2015

H8-BINOL chiral imidodiphosphoric acids catalyzed cyclization reactions of β,γ-unsaturated α-ketoesters, arylamines and 1,3-dicarbonyl compounds: enantioselective synthesis of 1,4-dihydropyridines

Tetrahedron Asymmetry

DOI

2014

ChemInform Abstract: Highly Enantioselective Biginelli Reaction Catalyzed by Double Axially Chiral Bisphosphorylimides.

ChemInform

DOI

2014

Straightforward Enzyme-Catalyzed Asymmetric Synthesis of Caffeic Acid Esters in Enantioenriched Form

Industrial & Engineering Chemistry Research

DOI

2013

Highly Enantioselective Biginelli Reaction Catalyzed by Double Axially Chiral Bisphosphorylimides

European Journal of Organic Chemistry

DOI

2013

Stereoselective synthesis of caffeic acid amides via enzyme-catalyzed asymmetric aminolysis reaction

Journal of Biotechnology

DOI

2013

ChemInform Abstract: Synthesis of Chiral Benzimidazoles as Acylating Agents for Kinetic Resolution of Racemic α‐Amino Esters.

ChemInform

DOI

2013

ChemInform Abstract: Double Axially Chiral Bisphosphorylimides as Novel Broensted Acids in Asymmetric Three‐Component Mannich Reaction.

ChemInform

DOI

2012

Synthesis of Chiral Benzimidazoles as Acylating Agents for Kinetic Resolution of Racemic α‐Amino Esters

Journal of Heterocyclic Chemistry

DOI

2012

Resolution of N-(2-ethyl-6-methylphenyl) alanine by using microgel beads containingPseudomonas cepacialipase

Biocatalysis and Biotransformation

DOI

2012

Double axially chiral bisphosphorylimides as novel Brønsted acids in asymmetric three-component Mannich reaction

Tetrahedron Asymmetry

DOI

2012

Study on the enantioselectivity inhibition mechanism of acetyl-coenzyme A carboxylase toward haloxyfop by homology modeling and MM-PBSA analysis

Journal of Molecular Modeling

DOI

2012

ChemInform Abstract: Novel Pyrrolidine‐Aminobenzimidazole Bifunctional Organocatalysts for Asymmetric Nitro‐Michael Reactions in Brine.

ChemInform

DOI

2012

ChemInform Abstract: Proline‐Based Dipeptides as Efficient Organocatalysts for Asymmetric Aldol Reactions in Brine.

ChemInform

DOI

2011

Enhancing lipase-catalyzed hydrolysis by adding macrocyclic tetraamines

Journal of Molecular Catalysis B Enzymatic

DOI

2011

ChemInform Abstract: One‐Pot and Microwave‐Assisted Synthesis of N‐Sulfonylaziridines.

ChemInform

DOI

2011

Novel pyrrolidine-aminobenzimidazole bifunctional organocatalysts for asymmetric nitro-Michael reactions in brine

Tetrahedron Asymmetry

DOI

2011

Proline-based dipeptides as efficient organocatalysts for asymmetric aldol reactions in brine

Tetrahedron Asymmetry

DOI

2011

One-pot and microwave-assisted synthesis of N-sulfonylaziridines

Tetrahedron Letters

DOI

2011

l-Valine Dipeptide Organocatalysts with Two Amide Units for the Direct Asymmetric Aldol Reaction in Brine

Catalysis Letters

DOI

2011

Resolution of 2-octanol via immobilizedPseudomonassp. lipase in organic medium

Biocatalysis and Biotransformation

DOI

2010

Novel Primary Amine Organocatalysts Derived from Cinchona Alkaloids for Asymmetric Direct Aldol Reactions in Brine

Catalysis Letters

DOI

2008

Cloning, Expression and Purification of Wheat Acetyl-CoA Carboxylases CT Domain in E. coil

Chemical Research in Chinese Universities

DOI

2008

Template enhanced activity of lipase accommodated in siliceous mesocellular foams

Biochemical and Biophysical Research Communications

DOI

2008

Resolution of N-(2-ethyl-6-methylphenyl) alanine via cross-linked aggregates of Pseudomonas sp. Lipase

Journal of Molecular Catalysis B Enzymatic

DOI

2007

Chemoenzymatic Synthesis of the Chiral Herbicide: (S)‐Metolachlor.

ChemInform

DOI

2007

Resolution ofN-(2-ethyl-6-methylphenyl) alanine catalyzed by Lipase B fromCandida antarctica

Biocatalysis and Biotransformation

DOI

2006

Study on the relationship between structure and enantioselectivity of a hyperthermophilic esterase from archaeon Aeropyrum pernix K1

Journal of Molecular Catalysis B Enzymatic

DOI

2006

Resolution of N-(2-ethyl-6-methylphenyl)alanine via free and immobilized lipase from Pseudomonas cepacia

Journal of Molecular Catalysis B Enzymatic

DOI

2005

利用酸值监测脂肪酶催化豆油水解反应的进程

《吉林大学学报(理学版)》

2005

Enhancement of enantioselectivity in lipase-catalyzed resolution of N-(2-ethyl-6-methylphenyl)alanine by additives

Journal of Molecular Catalysis B Enzymatic

DOI

2004

酶促拆分丁酸环氧丙酯反应体系的筛选

《生物加工过程》

2004

脂肪酶催化拆分N取代苯基α氨基丙酸的研究

《吉林大学》

2004

仿水溶剂促进酶促拆分环氧丙醇的研究

《吉林大学学报(理学版)》

2003

乙酰肉碱的化学合成与酶法拆分

《吉林大学学报(理学版)》

2001

丁酸环氧丙酯的化学合成与酶法拆分

《吉林大学学报(理学版)》

2017

Rational enhancement of the enantioselectivity of Candidaantarcticalipase B in kinetic resolution of N-(2-ethyl-6-methylphenyl) alanine

《第十一届中国酶工程学术研讨会论文摘要集》

2013

大环多胺化合物调控酶催化有机反应的分子机制研究

《第九届中国酶工程学术研讨会论文摘要集》

2005

酶法合成手性异丙甲草胺的研究

《中国化学会第四届有机化学学术会议论文集（下册）》

2004

酶催化拆分N-(2-甲基-6-乙基苯基)丙氨酸

《第三届全国有机化学学术会议》

2004

中孔分子筛SBA-15固定脂肪酶的研究

《2004年全国生物技术学术研讨会》

2004

脂肪酶催化糖酯合成反应的底物选择性研究

《2004年全国生物技术学术研讨会论文集》