张绪梅｜天津医科大学｜学者主页

2026

Obesity, metabolic health, and brain health: Insights from a prospective cohort study

Meng Wang, Lan Yu, Zonghang Tong, Guangbin Sun, Xiaojie Zhang, Qiang Zhang, Xiaolong Xing, Jie V. Zhao, Xumei Zhang, Xueli Yang

Journal Of Affective Disorders，Vol. 3920

DOI

2026

天津市医学生膳食模式与情绪健康关系研究

许嘉璇，孙辰，刘胜男，刘银玥，张绪梅，王璇

《现代预防医学》

DOI

2026

外周血中性粒细胞与淋巴细胞比值、血小板计数与淋巴细胞比值、单核细胞与高密度脂蛋白-胆固醇比值在合并颈动脉粥样硬化缺血性卒中患者中的变化及临床意义

张晓洁，石琳然，刘盛杰，王萌，康军，赵理乐，张利文，张绪梅

《陕西医学杂志》

2026

Bisdemethoxycurcumin extends lifespan and healthspan in Caenorhabditis elegans via modulation of EGFR-linked signaling pathways

Ruidie Shi, Yihan Zhang, Chaoxue Li, Xinyue Li, Chuyue Tu, Chen Sun, S.Y. Liu, Ruikun He, Xumei Zhang

Food & Function

DOI

2025

血清叶酸与首发缺血性脑卒中的相关性及lncRNA ANRIL的中介效应分析

佟宗航，王萌，刘银玥，余兰，刘盛杰，张绪梅

《营养学报》

2025

Effect of 3.1-THz radiation on pathological progression in Caenorhabditis elegans Alzheimer’s disease model

Lei 磊 Wang 王，Meng Wang，Xumei Zhang，Mingxia 明霞 He 何

Chinese Physics B

DOI

2025

Folic acid supplementation improves cognitive function in participants with cerebral small vascular disease-related cognitive impairment: a randomized controlled trial

Yinyue Liu, Zili Yu, Zhijun Cai, Li Zhao, Yu Wang, Yu Wang, Yajie Guo, Xiaonan Su, Yuli Miao, Bin Yi, Yanhong Wang, Yanhong Wang, Xumei Zhang

The Journal of Prevention of Alzheimer s Disease

DOI

2025

The involvement of the synaptic vesicle cycle in homocysteine induced neurotoxicity in vitro and in vivo

Meng Wang, Xiaoshan Liang, Keqing Jin, Yinyue Liu, Suhui Luo, Qiang Zhang, Xuan Wang, Zhiping Dong, Xumei Zhang

Scientific Reports

DOI

2025

The impact of folic acid deficiency on ischemic stroke: Role of inflammation and long noncoding RNA H19

Meng Wang, Linran Shi, Ziyi Tong, Yinyue Liu, Yuxuan Bai, Xueli Yang, Yanhong Wang, Zhongying Gong, Qiang Zhang, Xumei Zhang, Xumei Zhang

The Journal of Nutritional Biochemistry

DOI

2024

同型半胱氨酸和肾小球滤过率对缺血性脑血管病患者神经功能的影响

郭亚杰，王萌，常瑜，拱忠影，张绪梅

《中风与神经疾病杂志》

2024

多环芳烃内暴露对于血脂的影响以及氧化应激途径的中介作用——一项缺血性脑卒中的病例对照研究

张宁宇，贾文慧，刘盛杰，赵理乐，张绪梅，张利文

《环境与健康杂志》

2024

1-硝基芘通过自噬通路对秀丽隐杆线虫寿命的影响研究

付玉聪，王萌，刘盛杰，赵理乐，张绪梅，张利文

《职业与健康》

2024

虾青素通过自噬改善快速老化小鼠心脏组织损伤

靳可青，刘银玥，王萌，张绪梅

《天津医科大学学报》

2023

血清尿素氮、碱性磷酸酶与儿童营养不良的相关性分析

苟芸，张绪梅，杨军红，林莹，李凌燕，安冬，张凯

《现代生物医学进展》

2023

Arsenic metabolism, N6AMT1 and AS3MT single nucleotide polymorphisms, and their interaction on gestational diabetes mellitus in Chinese pregnant women.

Xiaoshan Liang, Guan-Shuai Guo, Yiyun Wang, Meng Wang, Xi Chen, Jingran Zhang, Shuying Li, Liangpo Liu, Qing-Yu Huang, Bo Cui, M. Zhang, Gui-Fan Sun, Naijun Tang, Xumei Zhang, Qiang Zhang

Environmental Research

DOI

2023

Folic acid deficiency exacerbates the inflammatory response of astrocytes after ischemia‐reperfusion by enhancing the interaction between IL‐6 and JAK‐1/pSTAT3

Man Cheng, Xiaoshan Liang, Linran Shi, Qiang Zhang, Liwen Zhang, Z. Gong, Suhui Luo, Xuan Wang, Xumei Zhang

CNS Neuroscience & Therapeutics

DOI

2023

Serum folate mediates the associations of MTHFR rs1801133 polymorphism with blood glucose levels and gestational diabetes mellitus in Chinese Han pregnant women

Yunguo Wang, Yiyun Wang, Yao Sun, N. Zhang, Xiaoshan Liang, Suhui Luo, Li-Rong Dai, Chao Sun, Yungui Yang, Shuying Li, Xumei Zhang, Qiang Zhang

British Journal of Nutrition

DOI

2022

虾青素调控ROS介导的自噬延长秀丽隐杆线虫寿命作用

付敏，张旭光，杨柳，张绪梅，刘欢

《食品工业科技》

2022

Folic Acid Ameliorates Synaptic Impairment following Cerebral Ischemia/Reperfusion Injury via Inhibiting Excessive Activation of NMDA Receptors.

Xiaoshan Liang, Linran Shi, Meng Wang, Liwen Zhang, Z. Gong, Suhui Luo, Xuan Wang, Qiang Zhang, Xumei Zhang

Journal of Nutritional Biochemistry

DOI

2022

Associations of Maternal rs1801131 Genotype in MTHFR and Serum Folate and Vitamin B12 with Gestational Diabetes Mellitus in Chinese Pregnant Women

Shuying Li, Xiu-biao Tian, Yiyun Wang, Xumei Zhang, Liwen Zhang, Chen Li, Jing Li, Chunhua Wang, Hui-Huan Liu, Juan Liu, Hong-Juan Liu, Xue-Li Yang, Wei-Qin Li, J. Leng, Xi-Lin Yang, Naijun Tang, Qiang Zhang

Nutrients

DOI

2022

Circulating folate concentrations and the risk of mild cognitive impairment: A prospective study on the older Chinese population without folic acid fortification

Jingzhu Fu, Qian Liu, Yun Zhu, Changqing Sun, Huilian Duan, Ling Huang, Dezheng Zhou, Zehao Wang, Jing Zhao, Zhen-Shu Li, F. Ma, Wen Li, Huan Liu, Xumei Zhang, Yong-Jie Chen, Guangshun Wang, Yue Du, Guo-Wei Huang

European Journal of Neurology

DOI

2022

Association between Dietary Patterns and the Risk of Depressive Symptoms in the Older Adults in Rural China

Jing Yan, Qinghan Ren, Hong-Yan Lin, Qian Liu, Jingzhu Fu, Changqing Sun, Wen Li, F. Ma, Yun Zhu, Zhen-Shu Li, Guoquan Zhang, Yue Du, Huan Liu, Xumei Zhang, Yong-Jie Chen, Guangshun Wang, Guo-Wei Huang

Nutrients

DOI

2022

Homocysteine can aggravate depressive like behaviors in a middle cerebral artery occlusion/reperfusion rat model: a possible role for NMDARs-mediated synaptic alterations

Meng-Ying Wang, Xiaoshan Liang, Qiang Zhang, Suhui Luo, Huan Liu, Xuan Wang, N. Sai, Xumei Zhang

Nutritional neuroscience

DOI

2022

Astaxanthin delays brain aging in senescence-accelerated mouse prone 10: inducing autophagy as a potential mechanism

Min Fu, Xiaoshan Liang, Xuguang Zhang, Xuguang Zhang, Mingzhe Yang, Qi Ye, Yuxuan Qi, Huan Liu, Xumei Zhang, Xumei Zhang

Nutritional Neuroscience

DOI

2022

Astaxanthin Regulates ROS-mediated Autophagy to Prolong Lifespan of Caenorhabditis elegans

Min Fu, Xuguang Zhang, Yang Liu, Xumei Zhang, Huan LIU

DOAJ (DOAJ: Directory of Open Access Journals)

DOI

2021

同型半胱氨酸经DNA甲基化对局灶性脑缺血大鼠大脑皮质区神经发生的影响

康军，苟芸，叶琦，梁晓珊，石琳然，王萌，李可，张绪梅

《中国脑血管病杂志》

2021

医学生自主学习能力现状研究

马冰，王璇，那日苏，吴蕴棠，张绪梅，刘欢，赛娜，李文，陈雯

《卫生职业教育》

2021

Interactions Between Handgrip Strength and Serum Folate and Homocysteine Levels on Cognitive Function in the Elderly Chinese Population

Yong-Jie Chen, Yue Du, Zhuo-Yu Sun, Qian Liu, Changqing Sun, Hong-Yan Lin, Mengdi Jin, Jingzhu Fu, F. Ma, Wen Li, Huan Liu, Xumei Zhang, Guangshun Wang, Guo-Wei Huang

Journal of Alzheimer's Disease

DOI

2021

Gender-specific prevalence and influencing factors of depression in elderly in rural China: A cross-sectional study.

Hong-Yan Lin, Mengdi Jin, Qian Liu, Yue Du, Jingzhu Fu, Changqing Sun, F. Ma, Wen Li, Huan Liu, Xumei Zhang, Yun Zhu, Yong-Jie Chen, Zhuo-Yu Sun, Guangshun Wang, Guo-Wei Huang, Jing Yan

Journal of Affective Disorders

DOI

2021

Homocysteine restrains hippocampal neurogenesis in focal ischemic rat brain by inhibiting DNA methylation.

Y. Gou, Qi Ye, Xiaoshan Liang, Qiang Zhang, Suhui Luo, Huan Liu, Xuan Wang, N. Sai, Xumei Zhang

Neurochemistry International

DOI

2021

Joint effect of urinary arsenic species and serum one-carbon metabolism nutrients on gestational diabetes mellitus: A cross-sectional study of Chinese pregnant women.

Qiang Zhang, Xumei Zhang, Shuying Li, Hui-Huan Liu, Liangpo Liu, Qing-Yu Huang, Yaxing Hou, Xiaoshan Liang, Bo Cui, Ming Zhang, Liting Xia, Liwen Zhang, Chen Li, Jing Li, Gui-Fan Sun, Naijun Tang

Environment International

DOI

2021

Pyrroloquinoline quinone extends Caenorhabditis elegans ’ longevity through the insulin/IGF1 signaling pathway-mediated activation of autophagy

Yang Liu, Ye Qi, Xuguang Zhang, Xuguang Zhang, Ke Li, Xiaoshan Liang, Meng Wang, Linran Shi, Suhui Luo, Qiang Zhang, Xumei Zhang, Xumei Zhang

Food & Function

DOI

2020

部分网络化PBL教学模式在预防医学生中应用效果反馈分析

王璇，吴蕴棠，赛娜，张绪梅，刘欢，李文，陈雯，黄国伟

《卫生职业教育》

2020

叶酸对肌萎缩性侧索硬化症线虫TAR DNA结合蛋白43(TDP-43）毒性的改善作用

杨柳，程曼，王梦影，梁晓珊，张绪梅

《现代食品科技》

DOI

2020

Folic Acid Deficiency Enhances the Tyr705 and Ser727 Phosphorylation of Mitochondrial STAT3 in In Vivo and In Vitro Models of Ischemic Stroke

Zhi-Ping Dong, Xiaoshan Liang, Qiang Zhang, Suhui Luo, Huan Liu, Xuan Wang, N. Sai, Xumei Zhang

Translational Stroke Research

DOI

2020

Associations of urinary phenolic environmental estrogens exposure with blood glucose levels and gestational diabetes mellitus in Chinese pregnant women.

Yaxing Hou, Shuying Li, Liting Xia, Qiao-Yun Yang, Li-Wen Zhang, Xumei Zhang, Hui-Huan Liu, Ran Huo, Guang-Han Cao, Chun-Nan Huang, Xiu-biao Tian, Li-Rong Sun, Deqing Cao, Ming Zhang, Qiang Zhang, Naijun Tang

Science of the Total Environment

DOI

2020

JAK2/STAT3 involves oxidative stress-induced cell injury in N2a cells and a rat MCAO model

Yan Sun, Man Cheng, Xiaoshan Liang, Shuang Chen, Meng-Ying Wang, Xumei Zhang

International Journal of Neuroscience

DOI

2020

Age- and Sex-Specific Prevalence and Modifiable Risk Factors of Mild Cognitive Impairment Among Older Adults in China: A Population-Based Observational Study

Jingzhu Fu, Qian Liu, Yue Du, Yun Zhu, Changqing Sun, Hong-Yan Lin, Mengdi Jin, F. Ma, Wen Li, Huan Liu, Xumei Zhang, Yong-Jie Chen, Zhuo-Yu Sun, Guangshun Wang, Guo-Wei Huang

Frontiers in Aging Neuroscience

DOI

2020

Autophagy Plays a Role in the Prolongation of the Life Span of Caenorhabditis elegans by Astaxanthin

Min Fu, Xumei Zhang, Xuguang Zhang, Liu Yang, Suhui Luo, Huan Liu

Rejuvenation Research

DOI

2019

大鼠脑缺血再灌注后大脑皮质小胶质细胞活化及炎症因子的表达

程曼，杨柳，王梦影，梁晓珊，张绪梅

《军事医学》

2019

膳食纤维肠内营养制剂对结直肠癌患者术后肠道屏障应激及营养指标的影响

万音，程曼，王梦影，杨柳，张绪梅

《天津医科大学学报》

2019

Folic acid deficiency enhanced microglial immune response via the Notch1/nuclear factor kappa B p65 pathway in hippocampus following rat brain I/R injury and BV2 cells

Man Cheng, Liu Yang, Zhi-Ping Dong, Meng-Ying Wang, Yan Sun, Huan Liu, Xuan Wang, N. Sai, Guo-Wei Huang, Xumei Zhang

Journal of Cellular and Molecular Medicine

DOI

2019

Homocysteine enhances neural stem cell autophagy in in vivo and in vitro model of ischemic stroke

Meng-Ying Wang, Xiaoshan Liang, Man Cheng, Liu Yang, Huan Liu, Xuan Wang, N. Sai, Xumei Zhang

Cell Death and Disease

DOI

2019

Joint effects of folate and vitamin B12 imbalance with maternal characteristics on gestational diabetes mellitus

Shuying Li, Yaxing Hou, Xing Yan, Yuwen Wang, Chen Shi, Xiaoyan Wu, Hui-Huan Liu, Liwen Zhang, Xumei Zhang, Juan Liu, Ming Zhang, Qiang Zhang, Naijun Tang

Journal of Diabetes

DOI

2018

预防医学生营养与食品卫生学课程网络学习资源使用现状调查及分析

王璇，张钰，吴蕴棠，赛娜，张绪梅，刘欢，黄国伟

《医学教育研究与实践》

2018

预防医学生营养与食品卫生学网络学习资源认知及需求情况调查

王璇，周丽慧，吴蕴棠，赛娜，张绪梅，刘欢，黄国伟

《卫生职业教育》

2018

预防医学专业学生营养与食品卫生学实验课学习现状调查

赛娜，吴蕴棠，李文，王璇，张绪梅，刘欢，黄国伟

《卫生职业教育》

2018

Maternal folic acid deficiency stimulates neural cell apoptosis via miR‐34a associated with Bcl‐2 in the rat foetal brain

Wen Li, Zhen-Shu Li, Dezheng Zhou, Xumei Zhang, Jing Yan, Guo-Wei Huang

International Journal of Developmental Neuroscience

DOI

2017

不同培养方式对大鼠原代神经干细胞自噬的影响

王梦影，黄国伟，程曼，董志萍，张绪梅

《中风与神经疾病杂志》

2017

炎症因子在缺血再灌注大鼠海马各亚区表达研究

程曼，刘朝琦，董志萍，王梦影，杨柳，张绪梅

《军事医学》

2017

Inhibitory effect of homocysteine on rat neural stem cell growth in vitro is associated with reduced protein levels and enzymatic activities of aconitase and respiratory complex III

Xumei Zhang, Ya-Qian Zhao, Hai Yan, Huan Liu, Guo-Wei Huang

Journal of Bioenergetics and Biomembranes

DOI

2017

Homocysteine induces mitochondrial dysfunction involving the crosstalk between oxidative stress and mitochondrial pSTAT3 in rat ischemic brain

Shuang Chen, Zhi-Ping Dong, Ya-Qian Zhao, N. Sai, Xuan Wang, Huan Liu, Guo-Wei Huang, Xumei Zhang

Scientific Reports

DOI

2017

Homocysteine exaggerates microglia activation and neuroinflammation through microglia localized STAT3 overactivation following ischemic stroke

Shuang Chen, Zhi-Ping Dong, Man Cheng, Ya-Qian Zhao, Meng-Ying Wang, N. Sai, Xuan Wang, Huan Liu, Guo-Wei Huang, Xumei Zhang

Journal of Neuroinflammation

DOI

2016

同型半胱氨酸对大鼠局灶性脑缺血后血管再生的影响

苟芸，黄国伟，赵亚倩，陈爽，张绪梅

《天津医药》

2016

大鼠局灶性脑缺血再灌注后大脑皮质神经元自噬的研究

赵亚倩，黄国伟，陈爽，苟芸，张绪梅

《军事医学》

2016

大鼠脑缺血再灌注后海马组织中GFAP和p-STAT3表达研究

陈爽，赵亚倩，董志萍，黄国伟，张绪梅

《军事医学》

2016

大鼠脑缺血再灌注后线粒体损伤及p-STAT3表达

陈爽，赵亚倩，苟芸，黄国伟，张绪梅

《天津医科大学学报》

2016

Dietary Changes over 25 Years in Tianjin Residents: Findings from the 1986–1988, 2000–2004, and 2008–2011 Nutrition Surveys

Xuan Wang, Yun-Tang Wu, Xumei Zhang, Meilin Zhang, Guo-Wei Huang

Nutrients

DOI

2016

Folic acid attenuates the effects of amyloid β oligomers on DNA methylation in neuronal cells

Huan Liu, Wen Li, Shijing Zhao, Xumei Zhang, Meilin Zhang, Yan-Yu Xiao, J. Wilson, Guo-Wei Huang

European Journal of Nutrition

DOI

2016

葉酸欠乏は局所脳虚血後のオートファジー増強を介して脳細胞損傷を増加させる【Powered by NICT】

Ya-Qian Zhao, Guo-Wei Huang, Shuang Chen, Y. Gou, Zhi-Ping Dong, Xumei Zhang

2016

脳虚血再灌流後の海馬組織におけるGFAPとP-STAT3の発現を研究した。【JST・京大機械翻訳】

Shuang Chen, Ya-Qian Zhao, Zhi-Ping Dong, Guo-Wei Huang, Xumei Zhang

2016

Folic acid deficiency increases brain cell injury via autophagy enhancement after focal cerebral ischemia.

Ya-Qian Zhao, Guo-Wei Huang, Shuang Chen, Y. Gou, Zhi-Ping Dong, Xumei Zhang

Journal of Nutritional Biochemistry

DOI

2016

Expression of GFAP and p-STAT3 in rat hippocampus following focal cerebral ischemia-reperfusion injury

Shuang Chen, Ya-Qian Zhao, Zhi-Ping Dong, Guo-Wei Huang, Xumei Zhang

2016

Homocysteine Aggravates Cortical Neural Cell Injury through Neuronal Autophagy Overactivation following Rat Cerebral Ischemia-Reperfusion

Ya-Qian Zhao, Guo-Wei Huang, Shuang Chen, Y. Gou, Zhi-Ping Dong, Xumei Zhang

International Journal of Molecular Sciences

DOI

2016

P4‐369: Folic Acid Modulate Presenilin 1 Inhibits Amyloid β‐Peptide Production in N2A‐App Cells

Wen Li, Huan Liu, Xumei Zhang, Guowei Huang

Alzheimer s & Dementia

DOI

2015

同型半胱氨酸对小鼠成神经瘤细胞毒性作用研究

苟芸，黄国伟，陈爽，张绪梅

《天津医科大学学报》

2015

Folic Acid Inhibits Amyloid β-Peptide Production through Modulating DNA Methyltransferase Activity in N2a-APP Cells

Wen Li, M. Jiang, Shijing Zhao, Huan Liu, Xumei Zhang, J. Wilson, Guo-Wei Huang

International Journal of Molecular Sciences

DOI

2015

Folic acid administration inhibits amyloid β-peptide accumulation in APP/PS1 transgenic mice.

Wen Li, Huan Liu, Min Yu, Xumei Zhang, Meilin Zhang, J. Wilson, Guo-Wei Huang

Journal of Nutritional Biochemistry

DOI

2015

Folic acid deficiency enhances abeta accumulation in APP/PS1 mice brain and decreases amyloid-associated miRNAs expression.

Huan Liu, Tian Tian, Shanchun Qin, Wen Li, Xumei Zhang, Xuan Wang, Yuxia Gao, Guo-Wei Huang

Journal of Nutritional Biochemistry

DOI

2015

Folic Acid Alters Methylation Profile of JAK-STAT and Long-Term Depression Signaling Pathways in Alzheimer’s Disease Models

Wen Li, Huan Liu, Min Yu, Xumei Zhang, Yan Zhang, Hongbo Liu, J. Wilson, Guo-Wei Huang

Molecular Neurobiology

DOI

2014

叶酸代谢基因缺失对ALS线虫运动能力影响

苟芸，黄国伟，樊丽宇，罗素慧，刘欢，张绪梅

《中国公共卫生》

2014

研究性学习法在预防医学实验教学中的应用

赛娜，张绪梅，吴蕴棠，黄国伟

《卫生职业教育》

2014

Homocysteine induces cytotoxicity and proliferation inhibition in neural stem cells via DNA methylation in vitro

N. Lin, Shanchun Qin, Suhui Luo, S. Cui, Guo-Wei Huang, Xumei Zhang

The FEBS Journal

DOI

2013

同型半胱氨酸对体外大鼠神经干细胞增殖及Notch信号通路相关基因表达的影响

林宁宁，张绪梅，秦善春，罗素慧，黄国伟

《天津医药》

2013

营养与食品卫生学实验教学改革探讨

张绪梅，黄国伟，吴蕴棠，赛娜

《基础医学教育》

2013

缺氧诱导神经干细胞凋亡作用机制研究

罗素慧，张绪梅，黄国伟

《天津医科大学学报》

2013

Effects of Homocysteine on ERK Signaling and Cell Proliferation in Fetal Neural Stem Cells In Vitro

Hai Yan, Xumei Zhang, Suhui Luo, Huan Liu, Xuan Wang, Yuxia Gao, J. Wilson, Guo-Wei Huang

Cell Biochemistry and Biophysics

DOI

2013

Folic acid stimulates proliferation of transplanted neural stem cells after focal cerebral ischemia in rats.

Huan Liu, Jiasong Cao, Hai-Hong Zhang, Shanchun Qin, Min Yu, Xumei Zhang, Xuan Wang, Yuxia Gao, J. Wilson, Guo-Wei Huang

Journal of Nutritional Biochemistry

DOI

2013

Folic Acid Acts Through DNA Methyltransferases to Induce the Differentiation of Neural Stem Cells into Neurons

Suhui Luo, Xumei Zhang, Min Yu, Hai Yan, Huan Liu, J. Wilson, Guo-Wei Huang

Cell Biochemistry and Biophysics

DOI

2012

Folic acid enhances Notch signaling, hippocampal neurogenesis, and cognitive function in a rat model of cerebral ischemia

Xumei Zhang, Guo-Wei Huang, Huan Liu, Hong Chang, J. Wilson

Nutritional neuroscience

DOI

2011

SELDI蛋白芯片技术检测叶酸对胎鼠神经干细胞作用的蛋白表达谱

张莹，常红，黄国伟，张绪梅

《营养学报》

2011

DETECTION OF THE PROTEINS PROFILE OF FETAL NEURAL STEM CELLS TREATED WITH FOLIC ACID BY SELDI PROTEIN CHIP TECHNOLOGY IN RAT

Xumei Zhang

Acta Nutrimenta Sinica

2010

叶酸对体外缺氧神经干细胞保护作用的研究

刘佳杰，刘欢，张绪梅，杨阳，尤清菊，黄国伟

《营养学报》

2010

叶酸对体外缺氧新生大鼠神经干细胞Hes5基因表达的影响

赵琳，张绪梅，刘欢，杨阳，尤清菊，刘佳杰，黄国伟

《天津医科大学学报》

2010

THE PROTECTIVE ROLE OF FOLATE ON NEURAL STEM CELLS UNDER HYPOXIA IN VITRO

Jia-Jie Liu, Huan Liu, Xumei Zhang, Yang Yang, Qing-Jun You, Guo-Wei Huang

2010

Folic Acid Supplementation Stimulates Notch Signaling and Cell Proliferation in Embryonic Neural Stem Cells

Huan Liu, Guo-Wei Huang, Xumei Zhang, Da-Lin Ren, J. Wilson

Journal of clinical biochemistry and nutrition

DOI

2009

叶酸对局灶性脑缺血大鼠神经细胞凋亡的影响

杜文平，黄国伟，张绪梅，刘欢，王广雷

《营养学报》

2009

叶酸对局灶性脑缺血大鼠血浆同型半胱氨酸的影响

卢瑾，黄国伟，常红，张绪梅，刘欢

《天津医药》

2009

甲氨蝶呤对体外培养神经干细胞的毒性作用

张绪梅，黄国伟，田志红，任大林

《天津医药》

2009

叶酸对局灶性脑梗死大鼠神经干细胞增殖作用的影响

赵莹，常红，黄国伟，张绪梅，杜文平，杨云霞

《天津医科大学学报》

2009

叶酸对缺氧新生鼠神经干细胞体外增殖的影响

尤清菊，张绪梅，刘欢，杨阳，赵琳，刘佳杰，黄国伟

《天津医科大学学报》

2009

Effects of folic acid on in vitro astrocytic differentiation of neural stem cells from neonatal rats

Xumei Zhang, Guowei Huang, Zhihong Tian, Guanglei Wang, Dalin Ren Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin 300070, China

Neural Regeneration Research

2009

Effects of soybean isoflavone on the notch signal pathway of the brain in rats with cerebral ischemia.

Guo-Wei Huang, Xiao-Hong Cao, Xumei Zhang, Hong Chang, Yun-Xia Yang, Wenp Du, J. Wilson

Journal of Nutritional Science and Vitaminology

DOI

2009

Folate stimulates ERK1/2 phosphorylation and cell proliferation in fetal neural stem cells

Xumei Zhang, Guo-Wei Huang, Zhi-Hong Tian, Da-Lin Ren, J. Wilson

Nutritional neuroscience

DOI

2009

EFFECTS OF FOLIC ACID ON APOPTOSIS OF NEURAL CELLS IN RATS WITH FOCAL CEREBRAL ISCHEMIA INJURY

Wen-Ping Du, Guo-Wei Huang, Xumei Zhang, Huan Liu, Guang-Lei Wang

2009

Folate Deficiency Induces Neural Stem Cell Apoptosis by Increasing Homocysteine In Vitro

Xumei Zhang, Guo-Wei Huang, Zhi-Hong Tian, Da-Lin Ren, J. Wilson

Journal of clinical biochemistry and nutrition

DOI

2008

叶酸对胎鼠大脑神经干细胞增殖蛋白表达影响

王广雷，黄国伟，张绪梅，丛革新，姬长珍，田志红

《中国公共卫生》

2008

胚胎大鼠神经干细胞体外分化的激光共聚焦显微镜观察

任大林，黄国伟，张绪梅，刘欢

《天津医药》

2008

叶酸对脑梗死大鼠星形胶质细胞GFAP表达的影响

赵莹，黄国伟，常红，张绪梅

《天津医药》

2008

叶酸对胎鼠神经干细胞体外增殖的影响

张绪梅，黄国伟，姬长珍，张文治，苏心

《营养学报》

2008

叶酸对脑梗塞大鼠神经细胞凋亡及Notch1 mRNA表达的影响

杨云霞，黄国伟，张绪梅，刘欢，卢瑾，任大林

《卫生研究》

2008

Effects of folate on proliferation of neural stem cells of fetal rat

Xumei Zhang

2008

Effect of Folate on GFAP Expression of Astrocytes in Rats with Cerebral Infarction

Xumei Zhang

Tianjin yiyao

2008

Effects of folate on notch signaling and cell proliferation in neural stem cells of neonatal rats in vitro.

Xumei Zhang, Huan Liu, Ge-Xin Cong, Zhi-Hong Tian, Da-Lin Ren, J. Wilson, Guo-Wei Huang

Journal of Nutritional Science and Vitaminology

DOI

2008

[Effects of folic acid on neural cell apoptosis and Notch1 mRNA expression in rats with brain infarction].

Yun-Xia Yang, Guo-Wei Huang, Xumei Zhang, Huan Liu

Wei sheng yan jiu = Journal of hygiene research

2007

适应21世纪人才发展需求的本科教学体系的建设与改革

吴蕴棠，黄国伟，张欣，常红，王宝亭，俞鸣，张绪梅，桑仲娜，刘莉

《继续医学教育》

2007

胎鼠神经干细胞分离培养和鉴定

田志红，黄国伟，姬长珍，张绪梅，王广雷，张文治，苏心

《天津医科大学学报》

精选作品

期刊论文

Obesity, metabolic health, and brain health: Insights from a prospective cohort study

天津市医学生膳食模式与情绪健康关系研究

外周血中性粒细胞与淋巴细胞比值、血小板计数与淋巴细胞比值、单核细胞与高密度脂蛋白-胆固醇比值在合并颈动脉粥样硬化缺血性卒中患者中的变化及临床意义

Bisdemethoxycurcumin extends lifespan and healthspan in Caenorhabditis elegans via modulation of EGFR-linked signaling pathways

血清叶酸与首发缺血性脑卒中的相关性及lncRNA ANRIL的中介效应分析

Effect of 3.1-THz radiation on pathological progression in Caenorhabditis elegans Alzheimer’s disease model

Folic acid supplementation improves cognitive function in participants with cerebral small vascular disease-related cognitive impairment: a randomized controlled trial

The involvement of the synaptic vesicle cycle in homocysteine induced neurotoxicity in vitro and in vivo

The impact of folic acid deficiency on ischemic stroke: Role of inflammation and long noncoding RNA H19

同型半胱氨酸和肾小球滤过率对缺血性脑血管病患者神经功能的影响

多环芳烃内暴露对于血脂的影响以及氧化应激途径的中介作用——一项缺血性脑卒中的病例对照研究

1-硝基芘通过自噬通路对秀丽隐杆线虫寿命的影响研究

虾青素通过自噬改善快速老化小鼠心脏组织损伤

血清尿素氮、碱性磷酸酶与儿童营养不良的相关性分析

Arsenic metabolism, N6AMT1 and AS3MT single nucleotide polymorphisms, and their interaction on gestational diabetes mellitus in Chinese pregnant women.

Folic acid deficiency exacerbates the inflammatory response of astrocytes after ischemia‐reperfusion by enhancing the interaction between IL‐6 and JAK‐1/pSTAT3

Serum folate mediates the associations of MTHFR rs1801133 polymorphism with blood glucose levels and gestational diabetes mellitus in Chinese Han pregnant women

虾青素调控ROS介导的自噬延长秀丽隐杆线虫寿命作用

Folic Acid Ameliorates Synaptic Impairment following Cerebral Ischemia/Reperfusion Injury via Inhibiting Excessive Activation of NMDA Receptors.

Associations of Maternal rs1801131 Genotype in MTHFR and Serum Folate and Vitamin B12 with Gestational Diabetes Mellitus in Chinese Pregnant Women

Circulating folate concentrations and the risk of mild cognitive impairment: A prospective study on the older Chinese population without folic acid fortification

Association between Dietary Patterns and the Risk of Depressive Symptoms in the Older Adults in Rural China

Homocysteine can aggravate depressive like behaviors in a middle cerebral artery occlusion/reperfusion rat model: a possible role for NMDARs-mediated synaptic alterations

Astaxanthin delays brain aging in senescence-accelerated mouse prone 10: inducing autophagy as a potential mechanism

Astaxanthin Regulates ROS-mediated Autophagy to Prolong Lifespan of Caenorhabditis elegans

同型半胱氨酸经DNA甲基化对局灶性脑缺血大鼠大脑皮质区神经发生的影响

医学生自主学习能力现状研究

Interactions Between Handgrip Strength and Serum Folate and Homocysteine Levels on Cognitive Function in the Elderly Chinese Population

Gender-specific prevalence and influencing factors of depression in elderly in rural China: A cross-sectional study.

Homocysteine restrains hippocampal neurogenesis in focal ischemic rat brain by inhibiting DNA methylation.

Joint effect of urinary arsenic species and serum one-carbon metabolism nutrients on gestational diabetes mellitus: A cross-sectional study of Chinese pregnant women.

Pyrroloquinoline quinone extends Caenorhabditis elegans ’ longevity through the insulin/IGF1 signaling pathway-mediated activation of autophagy

部分网络化PBL教学模式在预防医学生中应用效果反馈分析

叶酸对肌萎缩性侧索硬化症线虫TAR DNA结合蛋白43(TDP-43）毒性的改善作用

Folic Acid Deficiency Enhances the Tyr705 and Ser727 Phosphorylation of Mitochondrial STAT3 in In Vivo and In Vitro Models of Ischemic Stroke

Associations of urinary phenolic environmental estrogens exposure with blood glucose levels and gestational diabetes mellitus in Chinese pregnant women.

JAK2/STAT3 involves oxidative stress-induced cell injury in N2a cells and a rat MCAO model

Age- and Sex-Specific Prevalence and Modifiable Risk Factors of Mild Cognitive Impairment Among Older Adults in China: A Population-Based Observational Study

Autophagy Plays a Role in the Prolongation of the Life Span of Caenorhabditis elegans by Astaxanthin

大鼠脑缺血再灌注后大脑皮质小胶质细胞活化及炎症因子的表达

膳食纤维肠内营养制剂对结直肠癌患者术后肠道屏障应激及营养指标的影响

Folic acid deficiency enhanced microglial immune response via the Notch1/nuclear factor kappa B p65 pathway in hippocampus following rat brain I/R injury and BV2 cells

Homocysteine enhances neural stem cell autophagy in in vivo and in vitro model of ischemic stroke

Joint effects of folate and vitamin B12 imbalance with maternal characteristics on gestational diabetes mellitus

预防医学生营养与食品卫生学课程网络学习资源使用现状调查及分析

预防医学生营养与食品卫生学网络学习资源认知及需求情况调查

预防医学专业学生营养与食品卫生学实验课学习现状调查

Maternal folic acid deficiency stimulates neural cell apoptosis via miR‐34a associated with Bcl‐2 in the rat foetal brain

不同培养方式对大鼠原代神经干细胞自噬的影响

炎症因子在缺血再灌注大鼠海马各亚区表达研究

Inhibitory effect of homocysteine on rat neural stem cell growth in vitro is associated with reduced protein levels and enzymatic activities of aconitase and respiratory complex III

Homocysteine induces mitochondrial dysfunction involving the crosstalk between oxidative stress and mitochondrial pSTAT3 in rat ischemic brain

Homocysteine exaggerates microglia activation and neuroinflammation through microglia localized STAT3 overactivation following ischemic stroke

同型半胱氨酸对大鼠局灶性脑缺血后血管再生的影响

大鼠局灶性脑缺血再灌注后大脑皮质神经元自噬的研究

大鼠脑缺血再灌注后海马组织中GFAP和p-STAT3表达研究

大鼠脑缺血再灌注后线粒体损伤及p-STAT3表达

Dietary Changes over 25 Years in Tianjin Residents: Findings from the 1986–1988, 2000–2004, and 2008–2011 Nutrition Surveys

Folic acid attenuates the effects of amyloid β oligomers on DNA methylation in neuronal cells

葉酸欠乏は局所脳虚血後のオートファジー増強を介して脳細胞損傷を増加させる【Powered by NICT】

脳虚血再灌流後の海馬組織におけるGFAPとP-STAT3の発現を研究した。【JST・京大機械翻訳】

Folic acid deficiency increases brain cell injury via autophagy enhancement after focal cerebral ischemia.

Expression of GFAP and p-STAT3 in rat hippocampus following focal cerebral ischemia-reperfusion injury

Homocysteine Aggravates Cortical Neural Cell Injury through Neuronal Autophagy Overactivation following Rat Cerebral Ischemia-Reperfusion

P4‐369: Folic Acid Modulate Presenilin 1 Inhibits Amyloid β‐Peptide Production in N2A‐App Cells

同型半胱氨酸对小鼠成神经瘤细胞毒性作用研究

Folic Acid Inhibits Amyloid β-Peptide Production through Modulating DNA Methyltransferase Activity in N2a-APP Cells

Folic acid administration inhibits amyloid β-peptide accumulation in APP/PS1 transgenic mice.

Folic acid deficiency enhances abeta accumulation in APP/PS1 mice brain and decreases amyloid-associated miRNAs expression.

Folic Acid Alters Methylation Profile of JAK-STAT and Long-Term Depression Signaling Pathways in Alzheimer’s Disease Models

叶酸代谢基因缺失对ALS线虫运动能力影响

研究性学习法在预防医学实验教学中的应用

Homocysteine induces cytotoxicity and proliferation inhibition in neural stem cells via DNA methylation in vitro

同型半胱氨酸对体外大鼠神经干细胞增殖及Notch信号通路相关基因表达的影响

营养与食品卫生学实验教学改革探讨

缺氧诱导神经干细胞凋亡作用机制研究

Effects of Homocysteine on ERK Signaling and Cell Proliferation in Fetal Neural Stem Cells In Vitro

Folic acid stimulates proliferation of transplanted neural stem cells after focal cerebral ischemia in rats.