郑撼球｜清华大学｜学者主页

期刊论文

2024

OPG promotes lung metastasis by reducing CXCL10 production of monocyte-derived macrophages and decreasing NK cell recruitment

Haitian Hu, Xuan Li, Zhanao Xu, Yuwei Tao, Luyang Zhao, Huiwen You, Guoyuan Xu, Teng Zhang, Yuan Zhang, Huijuan Fan, Xu-Xiang Wang, Wenjin Chen, Christopher G. Lin, Hanqiu Zheng

EBioMedicine

DOI

2024

Lymphotoxin-β promotes breast cancer bone metastasis colonization and osteolytic outgrowth

Xu-Xiang Wang, Teng Zhang, Bing-Xin Zheng, Youxue Lu, Yong Liang, Guoyuan Xu, Luyang Zhao, Yuwei Tao, Qianhui Song, Huiwen You, Haitian Hu, Xuan Li, Keyong Sun, Tian-Qi Li, Zi-An Zhang, Jian-Bian Wang, Xun Lan, Deng Pan, Yangbo Fu, Bin Yue, Hanqiu Zheng

Nature Cell Biology

DOI

2024

The dual roles of lymphotoxin-β in promoting breast cancer bone metastasis

Xu-Xiang Wang, Hanqiu Zheng

Nature Cell Biology

DOI

2023

Osteoclast-Cancer Cell Metabolic Crosstalk Confers PARP Inhibitor Resistance in Bone Metastatic Breast Cancer.

Huijuan Fan, Zhanao Xu, Ke Yao, Bing-Xin Zheng, Yuan Zhang, Xu-Xiang Wang, Teng Zhang, Xuan Li, Haitian Hu, Bin Yue, Zeping Hu, Hanqiu Zheng

Cancer Research

DOI

2023

Osteoclast-Cancer Cell Metabolic Symbiosis Renders PARP Inhibitor Therapy Resistance in Bone Metastasis

Huijuan Fan, Zhanao Xu, Ke Yao, Bingxin Zheng, Yuan Zhang, Xu-Xiang Wang, Teng Zhang, Xuan Li, Haitian Hu, Bin Yue, Ze-Ping Hu, Hanqiu Zheng

bioRxiv

DOI

2022

Tumor-derived Jagged1 promotes cancer progression through immune evasion.

Jingjing Meng, Yi-Zhou Jiang, Shen Zhao, Yuwei Tao, Teng Zhang, Xu-Xiang Wang, Yuan Zhang, Keyong Sun, Min Yuan, Jin Chen, Yong Wei, Xun Lan, Mo Chen, Charles J. David, Zhi-Jie Chang, Xiao-Huan Guo, Deng Pan, Meng Chen, Z. Shao, Yi-Bin Kang, Hanqiu Zheng

Cell Reports

DOI

2020

ASB13 inhibits breast cancer metastasis through promoting SNAI2 degradation and relieving its transcriptional repression of YAP

Huijuan Fan, Xu-Xiang Wang, Wenyang Li, Minhong Shen, Yong Wei, Hanqiu Zheng, Yi-Bin Kang

Genes & Development

DOI

2020

Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2

Wenyang Li, Minhong Shen, Yi-Zhou Jiang, Rui-Na Zhang, Hanqiu Zheng, Yong Wei, Z. Shao, Yi-Bin Kang

Genes & Development

DOI

2019

Bone Vascular Niche E-selectin Induces Mesenchymal-Epithelial Transition and Wnt Activation in Cancer Cells to Promote Bone Metastasis

M. Esposito, Nandini Mondal, T. Greco, Yong Wei, C. Spadazzi, Song-Chang Lin, Hanqiu Zheng, C. Cheung, J. Magnani, Sue-Hwa Lin, I. Cristea, R. Sackstein, Yi-Bin Kang

Nature Cell Biology

DOI

2019

Abstract 162: ASB13 inhibits breast cancer progression and metastasis through SNAI2 degradation and transcriptional regulation of YAP

Huijuan Fan, Xu-Xiang Wang, Wenyang Li, Minhong Shen, Yong Wei, Hanqiu Zheng, Yi-Bin Kang

Tumor Biology

DOI

2019

Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling.

Minhong Shen, Yi-Zhou Jiang, Yong Wei, Brian J. Ell, Xin-Lei Sheng, M. Esposito, Jooeun Kang, Xiang Hang, Hanqiu Zheng, Michelle Rowicki, Lan-Jing Zhang, W. Shih, Toni Celià-Terrassa, Yi-Rong Liu, I. Cristea, Z. Shao, Yi-Bin Kang

Cancer Cell

DOI

2019

Abstract 162: ASB13 inhibits breast cancer progression and metastasis through SNAI2 degradation and transcriptional regulation of YAP

Huijuan Fan, Xuxiang Wang, Wenyang Li, Minhong Shen, Yong Wei, Hanqiu Zheng, Yibin Kang

Cancer Research

DOI

2017

Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy

Hanqiu Zheng, Yangjin Bae, S. Kasimir-Bauer, Rebecca Tang, Jin Chen, G. Ren, Min Yuan, M. Esposito, Wenyang Li, Yong Wei, Minhong Shen, Lan-Jing Zhang, N. Tupitsyn, K. Pantel, C. King, Jan Sun, J. Moriguchi, He Jun, A. Coxon, Brendan H. Lee, Yi-Bin Kang

Cancer Cell

DOI

2016

Tumor-Stroma Interactions in Bone Metastasis: Molecular Mechanisms and Therapeutic Implications.

Hanqiu Zheng, Wenyang Li, Yi-Bin Kang

Cold Spring Harbor Symposia on Quantitative Biology

DOI

2015

Cradle of evil: osteogenic niche for early bone metastasis.

Hanqiu Zheng, Yi-Bin Kang

Cancer Cell

DOI

2014

Multilayer control of the EMT master regulators

Hanqiu Zheng, Yi-Bin Kang

Oncogene

DOI

2014

PKD1 phosphorylation-dependent degradation of SNAIL by SCF-FBXO11 regulates epithelial-mesenchymal transition and metastasis

Hanqiu Zheng, Minhong Shen, Yin-Lian Zha, Wenyang Li, Yong Wei, M. A. Blanco, G. Ren, Tian-Hua Zhou, P. Storz, Hui-Yun Wang, Yi-Bin Kang

Cancer Cell

DOI

2010

FBW7-KLF5-FGF-BP: An emerging pathway in breast cancer

Hanqiu Zheng

2009

Krüppel-like factor 5 promotes breast cell proliferation partially through upregulating the transcription of fibroblast growth factor binding protein 1

Hanqiu Zheng, Zhongmei Zhou, Jian Huang, L. Chaudhury, Jin-Tang Dong, Ce-Shi Chen

Oncogene

DOI

书籍章节

2022

Targeting Metastatic Disease: Challenges and New Opportunities

Haitian Hu, Zeping Hu, Hanqiu Zheng

Springer eBooks

DOI

郑撼球

精选作品

期刊论文

OPG promotes lung metastasis by reducing CXCL10 production of monocyte-derived macrophages and decreasing NK cell recruitment

Lymphotoxin-β promotes breast cancer bone metastasis colonization and osteolytic outgrowth

The dual roles of lymphotoxin-β in promoting breast cancer bone metastasis

Osteoclast-Cancer Cell Metabolic Crosstalk Confers PARP Inhibitor Resistance in Bone Metastatic Breast Cancer.

Osteoclast-Cancer Cell Metabolic Symbiosis Renders PARP Inhibitor Therapy Resistance in Bone Metastasis

Tumor-derived Jagged1 promotes cancer progression through immune evasion.

ASB13 inhibits breast cancer metastasis through promoting SNAI2 degradation and relieving its transcriptional repression of YAP

Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2

Bone Vascular Niche E-selectin Induces Mesenchymal-Epithelial Transition and Wnt Activation in Cancer Cells to Promote Bone Metastasis

Abstract 162: ASB13 inhibits breast cancer progression and metastasis through SNAI2 degradation and transcriptional regulation of YAP

Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling.

Abstract 162: ASB13 inhibits breast cancer progression and metastasis through SNAI2 degradation and transcriptional regulation of YAP

Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy

Tumor-Stroma Interactions in Bone Metastasis: Molecular Mechanisms and Therapeutic Implications.

Cradle of evil: osteogenic niche for early bone metastasis.

Multilayer control of the EMT master regulators

PKD1 phosphorylation-dependent degradation of SNAIL by SCF-FBXO11 regulates epithelial-mesenchymal transition and metastasis

FBW7-KLF5-FGF-BP: An emerging pathway in breast cancer

Krüppel-like factor 5 promotes breast cell proliferation partially through upregulating the transcription of fibroblast growth factor binding protein 1

书籍章节

Targeting Metastatic Disease: Challenges and New Opportunities

研究方向