百晓学者学者目录

郑雯益

副教授、教授，重庆医科大学

精选作品

期刊论文

2026

Quantitative Assessment of shRNA Loading and Delivery Efficiency of Engineered Extracellular Vesicles

J. Rädler, Giulia Corso, Omnia Elsharkasy, N. Kamei, Doste R. Mamand, Xiuming Liang, Wenyi Zheng, A. Zickler, Hou-Ze Zhou, S. Roudi, O. Wiklander, I. Mäger, Dhanu Gupta, S. el Andaloussi

bioRxiv

DOI

2026

Injected extracellular vesicles and other nanoparticles hitchhike on erythrocytes and platelets from circulation towards organ clearance

Svetlana Pavlova, Doste R. Mamand, Daniel W. Hagey, Xiuming Liang, H. Y. Estupiñán, Wenyi Zheng, Guannan Zhou, R. Amin, A. Zickler, Scott Bonner-Harris, Zankruti Dave, M. Ojansivu, Manuela O Gustafsson, O. Hayes, O. Wiklander, Manuchehr Abedi-Valugerdi, S. Roudi, A. Marquant, Joel Z. Nordin, M. Stevens, Andre Görgens, S. el Andaloussi

Extracellular Vesicle

DOI

2025

Systemic Inflammation Modulates Clearance and Drives Extra‐Hepatic Distribution of Extracellular Vesicles

Svetlana Pavlova, Doste R. Mamand, Andre Görgens, A. Zickler, Wenyi Zheng, Xiuming Liang, O. Wiklander, Manuchehr Abedi-Valugerdi, E. Van Wonterghem, Junhua Xie, Zheyu Niu, S. Roudi, Dong-Nan Yan, Ruhani Makkar, Guannan Zhou, Koshi Imami, Matthew J. A. Wood, R. Vandenbroucke, Dhanu Gupta, S. el Andaloussi

bioRxiv

DOI

2025

Engineering of extracellular vesicles for efficient intracellular delivery of multimodal therapeutics including genome editors

Xiuming Liang, Dhanu Gupta, Junhua Xie, E. Van Wonterghem, Lien Van Hoecke, Justin Hean, Zheyu Niu, Marziyeh Ghaeidamini, O. Wiklander, Wenyi Zheng, Rim Jawad Wiklander, Rui He, Doste R. Mamand, J. Bost, Guannan Zhou, Hou-Ze Zhou, S. Roudi, H. Y. Estupiñán, J. Rädler, A. Zickler, Andre Görgens, Vicky W. Q. Hou, Radka Slovak, Daniel W. Hagey, Olivier G. de Jong, A. G. Uy, Yuanyuan Zong, I. Mäger, Carla Martín Pérez, Thomas C. Roberts, Dave Carter, P. Vader, E. Esbjörner, Antonin de Fougerolles, Matthew J. A. Wood, R. Vandenbroucke, Joel Z. Nordin, S. el Andaloussi

Nature Communications

DOI

2025

Screening scaffold proteins for improved functional delivery of luminal proteins using engineered extracellular vesicles.

Zheyu Niu, Hou-Ze Zhou, Wenyi Zheng, O. Hayes, Vicky W. Q. Hou, Andre Görgens, S. Roudi, Guannan Zhou, Rim Jawad Wiklander, Taras Sych, E. Sezgin, Joel Z. Nordin, Ying Zhao, Xiuming Liang, Samir E. L. Andaloussi

Journal of Controlled Release

DOI

2025

Development of Endogenous Protein Probes for Characterizing Surface Proteins and Cellular Interactors of Extracellular Vesicles

Wenyi Zheng, M. Mowoe, Wenqing Hou, D. Hagey, Koshi Imami, S. el Andaloussi

Advancement of science

DOI

2025

Genetic tools for investigating the life cycle of extracellular vesicles

Wenyi Zheng, S. Roudi, Hou-Ze Zhou, Maribel Lara Corona, G. van Niel, Joel Z. Nordin, S. el Andaloussi

Nature Reviews Bioengineering

DOI

2024

Surface display of proximity labeling enzymes on extracellular vesicles for surfaceome and target cell mapping

Wenyi Zheng, M. Mowoe, Wenqing Hou, D. Hagey, Koshi Imami, S. el Andaloussi

bioRxiv

DOI

2024

Antibody-displaying extracellular vesicles for targeted cancer therapy

O. Wiklander, Doste R. Mamand, D. K. Mohammad, Wenyi Zheng, Rim Jawad Wiklander, Taras Sych, A. Zickler, Xiuming Liang, H. Sharma, Andrea Lavado, J. Bost, S. Roudi, Giulia Corso, Angus J Lennaárd, Manuchehr Abedi-Valugerdi, I. Mäger, E. Alici, E. Sezgin, Joel Z. Nordin, Dhanu Gupta, Andre Görgens, S. el Andaloussi

Nature Biomedical Engineering

DOI

2023

Identification of scaffold proteins for improved endogenous engineering of extracellular vesicles

Wenyi Zheng, J. Rädler, Helena Sork, Zheyu Niu, S. Roudi, J. Bost, Andre Görgens, Ying Zhao, Doste R. Mamand, Xiuming Liang, O. Wiklander, Taavi Lehto, Dhanu Gupta, Joel Z. Nordin, S. el Andaloussi

Nature Communications

DOI

2023

Surface display of functional moieties on extracellular vesicles using lipid anchors.

Wenyi Zheng, Melanie Schürz, Rim Jawad Wiklander, Oskar Gustafsson, Dhanu Gupta, Radka Slovak, Andrei Traista, Arianna Coluzzi, S. Roudi, A. Barone, D. Farcas, Eleni Kyriakopoulou, Valentina Galli, Heena Sharma, N. Meisner-Kober, M. Honcharenko, Samir E. L. Andaloussi

Journal of Controlled Release

DOI

2023

EV-mediated promotion of myogenic differentiation is dependent on dose, collection medium, and isolation method

Britt Hanson, Ioulia Vorobieva, Wenyi Zheng, Mariana Conceição, Y. Lomonosova, I. Mäger, P. L. Puri, S. el Andaloussi, M. Wood, T. Roberts

Molecular Therapy: Nucleic Acids

DOI

2022

Cell‐specific targeting of extracellular vesicles through engineering the glycocalyx

Wenyi Zheng, Rui He, Xiuming Liang, S. Roudi, J. Bost, P. Coly, G. van Niel, Samir E. L. Andaloussi

Journal of Extracellular Vesicles

DOI

2022

Extracellular vesicles engineered to bind albumin demonstrate extended circulation time and lymph node accumulation in mouse models

Xiuming Liang, Z. Niu, Valentina Galli, Natalie Howe, Ying Zhao, O. Wiklander, Wenyi Zheng, Rim Jawad Wiklander, Giulia Corso, Christopher Davies, Justin Hean, Eleni Kyriakopoulou, Doste R. Mamand, R. Amin, Joel Z. Nordin, Dhanu Gupta, S. el Andaloussi

Journal of Extracellular Vesicles

DOI

2022

Identification of storage conditions stabilizing extracellular vesicles preparations

Andre Görgens, Giulia Corso, Daniel W. Hagey, Rim Jawad Wiklander, Manuela O. Gustafsson, U. Felldin, Y. Lee, R. B. Bostancioglu, Helena Sork, Xiuming Liang, Wenyi Zheng, D. K. Mohammad, S. I. van de Wakker, P. Vader, A. Zickler, Doste R. Mamand, Li Ma, M. Holme, M. Stevens, O. Wiklander, S. el Andaloussi

Journal of Extracellular Vesicles

DOI

2021

Growth Media Conditions Influence the Secretion Route and Release Levels of Engineered Extracellular Vesicles

J. Bost, O. Saher, Daniel W. Hagey, Doste R. Mamand, Xiuming Liang, Wenyi Zheng, Giulia Corso, Oskar Gustafsson, Andre Görgens, C. Smith, R. Zain, S. el Andaloussi, Dhanu Gupta

Advanced Healthcare Materials

DOI

2020

A general covalent binding model between cytotoxic selenocompounds and albumin revealed by mass spectrometry and X-ray absorption spectroscopy

Wenyi Zheng, Rui He, R. Boada, M. Subirana, T. Ginman, H. Ottosson, M. Valiente, Ying Zhao, M. Hassan

Scientific Reports

DOI

2020

Functional Nanocarriers for Drug Delivery by Surface Engineering of Polymeric Nanoparticle Post-Polymerization-Induced Self-Assembly

H. Asem, Wenyi Zheng, F. Nilsson, Yu-Ning Zhang, M. Hedenqvist, Moustapha Hassan, E. Malmström

ACS Applied Bio Materials

DOI

2020

Selenocompounds in leukemia treatment : advantages and pitfalls

Wenyi Zheng

2019

Extracellular Albumin Covalently Sequesters Selenocompounds and Determines Cytotoxicity

Wenyi Zheng, R. Boada, Rui He, Tingting Xiao, Fei Ye, L. Simonelli, M. Valiente, Ying Zhao, M. Hassan

International Journal of Molecular Sciences

DOI

2017

Rapid and Robust Quantification of p-Xyleneselenocyanate in Plasma via Derivatization.

Wenyi Zheng, Fadwa Benkessou, Brigitte Twelkmeyer, Siyao Wang, T. Ginman, H. Ottosson, M. Abedi‐Valugerdi, M. Subirana, Ying Zhao, M. Hassan

Analytical Chemistry

DOI

2017

Importance of the surface chemistry of nanoparticles on peroxidase-like activity.

R. El-Sayed, Fei Ye, H. Asem, Radwa M. Ashour, Wenyi Zheng, M. Muhammed, M. Hassan

Biochemical and Biophysical Research Communications - BBRC

DOI

2014

Synthesis and Optimization of a Bifunctional Hyaluronan‐Based Camptothecin Prodrug

Zaiyang Xu, Wenyi Zheng, Zong-Ning Yin

Archiv der Pharmazie

DOI

2014

Fabrication of biocompatible and tumor-targeting hyaluronan nanospheres by a modified desolvation method.

Wenyi Zheng, Yongquan Li, Jin-Ping Du, Zong-Ning Yin

Journal of Pharmacy and Science

DOI

2013

Improved stability and tumor targeting of 5‐fluorouracil by conjugation with hyaluronan

Zhikui Dong, Wenyi Zheng, Zaiyang Xu, Zong-Ning Yin

DOI

研究方向

l构建新型病毒和非病毒载体，用于递送小分子药物以及包括核酸和蛋白在内的大分子药物

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