谢国明｜重庆医科大学｜学者主页

2026

HPMES: an ultra-sensitive mutation enrichment strategy for FLT3-ITD MRD monitoring in acute myeloid leukemia

Manlu Yang, Wei Wu, Huili Bai, Jie Zhao, Yijie Gong, Li Wang, Tianzi Wang, Shiyi Feng, Xie Guoming, Li Yang, Junjie Li, Xueping Chen

Biosensors and Bioelectronics

DOI

2026

Bioinspired Compartmentalization Coupled with DNA-Gated Magnetic Nanoprobes Enables Simultaneous Electrochemical Detection of Dual MicroRNAs

Jiangbo Dong, Beibei Yu, Lili Zou, Ke Lv, Guoming Xie, Gang Yang

Analytical Chemistry

DOI

2026

Input-Triggered Allosteric Activation of CRISPR–Cas12a by Modular Loop-Engineered Hairpins

Na Yin, Li Zhang, Ruiling Lu, Hongyan Yu, Weitao Wang, Ke Lv, Yang Peng, Xiaole Han, Yaoyi Zhang, Yuhan Chen, Ziheng Zhang, Bianqin Guo, Gang Yang, Guoming Xie

ACS Sensors

DOI

2026

CAMERA: A programmable CRISPR-gated logic system for high-fidelity assessment of Mycobacterium tuberculosis

Jiu Pu, Dan Bai, Yaoyi Zhang, Yiqi Zhang, Li Zhang, Yu He, You Wu, You Wu, Zhe He, Zhe He, Shun Yao, Yongchang Wu, Lihua Yu, Yongchang Wu, Lihua Yu, Guoming Xie

Chemical Engineering Journal

DOI

2026

A structural accessibility principle for LbuCas13a activation by noncontiguous DNA

W Y Wang, Yuhan Chen, Z Li, Li Zhang, Kai Gui, You Wu, Na Yin, X Han, Yaoyi Zhang, Ruiling Lu, Z Zhang, L Wang, Guoming Xie

Nucleic Acids Research

DOI

2026

Programmable pH-responsive DNA inter-strand matching (PRISM) for precision molecular band-pass actuation

Xiaole Han, Hongyan Yu, Xiaomei Lin, Li Zhang, Weitao Wang, Yaoyi Zhang, Jianbo Jiang, Xingyu Liu, Ke Lv, Guoming Xie

Theranostics

DOI

2026

A spatiotemporally separated recognition–amplification strategy based on an M13 phage biological lever for immunodetection of bacteria

Chenlu Zhang, Fumei Cheng, Juanjuan Mou, Xiangyang Xiao, Xiaole Han, Li Zhang, L Wang, Guoming Xie, Yushun Wan, Y S Yang

Chemical Engineering Journal

DOI

2026

Dephosphorylation-regulated MNAzyme-PER cascade as a programmable converter for multi-task molecular actuation

Yaoyi Zhang, Yiqi Zhang, Jianbo Jiang, Dan Bai, Li Zhang, Li Wang, Xingping Hu, Jiu Pu, Yu He, Xiaole Han, Weitao Wang, Na Yin, Xiaomei Lin, Xingyu Liu, Tingmei Chen, Yongcan Guo, Guoming Xie

Journal of Nanobiotechnology

DOI

2026

Hairpin-Mediated TMSDR-CHA Signal Conversion for Highly Specific Single-Base Discrimination of EGFR L858R Mutation

Qi Gao, Yao Cheng, Kun Zhou, Jingjing He, Yongmin Liu, Ci Wang, Guoming Xie

Analytical Chemistry

DOI

2026

Detachable TMSD-CRISPR for programmable and highly specific discrimination of DNA/RNA mutations

Y Y Zhang, Wang Luo, Yaoyi Zhang, Y F He, Li Zhang, Y J Wu, Kejia Wu, Hongyan Yu, Xiaole Han, Na Yin, Jiu Pu, Dan Bai, Zhe He, Ke Lv, L Wang, Rongzhong Huang, Yang Sun, Guoming Xie

Chemical Engineering Journal

DOI

2026

A universal and orthogonal safety valve for CRISPR/Cas12a without chemical modification or external stimulation

Wang Luo, Y J Wu, Dongsheng Ni, Li Zhang, Y Y Zhang, Xiaole Han, Yaoyi Zhang, Jiu Pu, Y F He, Na Yin, Weitao Wang, Rongzhong Huang, Yongcan Guo, Yang Sun, Guoming Xie

Nucleic Acids Research

DOI

2026

An aptamer-mediated EXPAR fluorescence biosensor for early and sensitive detection of Aβ42 and Aβ40

Haoyu Wu, Chengsen Chai, M.D.SAIMUL ISLAM, Shangchun Sheng, Guoming Xie, Tingmei Chen

Analytica Chimica Acta

DOI

2026

Rational design of CRISPR–Cas12a crRNAs for enhanced allelic discrimination and low-abundance variant detection

Wei Wu, Yijie Gong, Mengjun Deng, Manlu Yang, Lifeng Wang, Yuanyuan Wang, Li Yang (6520), Xueping Chen, Guoming Xie, Junjie Li

Chemical Engineering Journal

DOI

2026

A DNAzyme-CRISPR cascade strategy for preamplification-free detection of Mycobacterium tuberculosis

Ying Qing Yu, Jianhong Zhang, Guoming Xie, Yu Lin, Yue Huang, Chenxin Rao, Yulei Hou, Hui Chen

Biosensors and Bioelectronics

DOI

2025

OS11.7.A IMAGING OF MOLECULAR BOUNDARIES IN GLIOBLASTOMAUSING PROGRAMMABLE PH-RESPONSIVE DNA NANOPROBES

Ke Lv, Xue Han, Guoming Xie, Gang Yang

Neuro-Oncology

DOI

2025

Rational design of tunable pH switches through shadow-strand hybridization-actuated displacement engineering

Xiaole Han, Xiangyu Dong, Xiaomei Lin, Hongyan Yu, Li Zhang, Weitao Wang, Yaoyi Zhang, Jianbo Jiang, Xingyu Liu, Gang Qiang Yang, Yongcan Guo, Guoming Xie

Nucleic Acids Research

DOI

2025

A dual-antibody sandwich immunoassay using upconversion nanoparticles and magnetic beads for fibrinogen detection

Ke Lv, Weitao Wang, Li Zhang, Xi Zhou, Hongyan Yu, Xiaole Han, Li Wang, Guoming Xie, Gang Yang

Analytical Sciences

DOI

2025

Click Chemistry-Accelerated DNA Strand Displacement Reaction

Li Zhang, Guoming Xie, Min Qing

Analytical Chemistry

DOI

2025

Design of mismatch closure for enhanced specificity in DNA strand displacement reactions

Hongyan Yu, Xiaole Han, Li Zhang, Na Yin, Li Wang, Ke Lv, Yongchang Wu, Dan Bai, Weitao Wang, Ying Huang, Xingping Hu, Zhi Weng, Chenlu Zhang, Gang Qiang Yang, Tingmei Chen, Guoming Xie

Nucleic Acids Research

DOI

2025

Ultra-sensitive detection of complex SNVs via allele-specific dPCR enhanced by multi-strand displacement reaction

Mengjun Deng, Xueping Chen, Guoming Xie, Junjie Li

Chemical Engineering Journal

DOI

2025

Smart Energy-Storing DNA Hydrogel for On-Demand Laser-Free Photoimmunotherapy of Melanoma

Huaixin Zhao, Lijun Wang, Sen Yeu Yang, Zhuiyun Li, Xiaocui Guo, Zuo Chen, Guoming Xie, Chi Yao, Dayong Yang

Journal of the American Chemical Society

DOI

2025

Triple-Layer locked nanodevice synergizes with Pd@PdPtRh nanozyme and 3D conductive nanocomplex for ultrasensitive dual-miRNA electrochemical biosensing

Xi Zhou, Li Zhang, Gaoli Zhang, Guoming Xie, Weixian Chen

Chemical Engineering Journal

DOI

2025

Regulation of CRISPR trans-cleavage activity by an overhanging activator

Na Yin, Hongyan Yu, Li Zhang, Fei Luo, Weitao Wang, Xiaole Han, Yu He, Yiqi Zhang, You Wu, Jiu Pu, Tong Feng, Gang Qiang Yang, Tingmei Chen, Guoming Xie

Nucleic Acids Research

DOI

2025

Logical Analysis of Multiple miRNAs with Isothermal Molecular Classifiers Based on LATE-RCA

Tong Feng, Li Zhang, Ding Wang, Zuo Chen, Yaoyi Zhang, Di Wu, Weitao Wang, Hongyan Yu, Dan Bai, Huaixin Zhao, Yongcan Guo, Guoming Xie

Nano Letters

DOI

2025

Engineering thermostable fluorescent DNA aptamer for the isothermal amplification of nucleic acids

Li Zhang, Tong Feng, Qian Liu, Chen Zuo, Yongchang Wu, Huaixin Zhao, Hongyan Yu, Dan Bai, Xiaole Han, Na Yin, Jiu Pu, Yujun Yang, Junjie Li, Jinhong Guo, Shixiong Deng, Guoming Xie

Biosensors and Bioelectronics

DOI

2025

Specific fluorescence detection strategy for single-stranded nucleic acids by dual-toehold branch migration

Yu Lin, Yaxing Xie, Guoming Xie, Jianhong Zhang, Ying Qing Yu, Yu‐Lei Hou, Hui Chen

Analytical Methods

DOI

2024

Dynamic Time-Programming Circuit for Encoding Information, Programming Dissipative Systems, and Delaying Release of Cargo

Luojia Wang, Zhongzhong Wang, Luo Wang, Heping Zhao, Guoming Xie

ACS Applied Bio Materials

DOI

2024

A phage amplification-assisted SEA-CRISPR/Cas12a system for viable bacteria detection

Xiangyang Xiao, Chenlu Zhang, Li Zhang, Chen Zuo, Wei Wu, Fumei Cheng, Di Wu, Guoming Xie, Xiang Mao, Yujun Yang

Journal of Materials Chemistry B

DOI

2024

Sequence-Unconstrained DNA Computing: DSN cycling and PER circuitry for dynamic miRNAs analysis and multifunctional logic operations

Dan Bai, Yaoyi Zhang, Jiu Pu, Li Zhang, Hongyan Yu, Xiaole Han, Ke Lv, Li Wang, Junjie Li, Ao Tang, Luo Wang, You Wu, Yiqi Zhang, Xi Zhou, Weitao Wang, Tong Feng, Bianqin Guo, Guoming Xie

Chemical Engineering Journal

DOI

2024

Allosteric stem-loop multicomponent DNAzyme: A versatile stimuli-responsive switch for nanotweezer operations and multifunctional biosensing

Yaoyi Zhang, Dan Bai, Jiu Pu, Li Zhang, Weitao Wang, Tong Feng, Jianhong Zhang, Hongyan Yu, Xiaole Han, Ke Lv, Li Wang, Yongcan Guo, Guoming Xie

Chemical Engineering Journal

DOI

2024

Design of enhanced entropy-driven non-covalent DNA catalytic reactions via the paired junction structure

Weitao Wang, Hongyan Yu, Xiaole Han, Li Zhang, Zhi Weng, Zuo Chen, Na Yin, Yaoyi Zhang, Tong Feng, Dan Bai, Ao Tang, Yongcan Guo, Ke Lv, Guoming Xie

Chemical Engineering Journal

DOI

2024

Three-way junction-mediated three-letter coded SDA cascade CRISPR/Cas12a system for circRNA detection

Di Wu, Xin Liu, Lujia Tang, Baiying Li, Rong Zhao, Tong Feng, Xiangyang Xiao, Guoming Xie, Wenli Feng

Chemical Engineering Journal

DOI

2024

AND Logic-Gate-Based Dual-Locking Probe System for the Sensitive Detection of microRNA and APE1

Jiani Wang, Xiaole Han, Hongyan Yu, Guoming Xie

Analytical Chemistry

DOI

2024

Modified Unit-Mediated Strand Displacement Reactions for Direct Detection of Single Nucleotide Variants in Active Double-Stranded DNA

Hongyan Yu, Xiaole Han, Weitao Wang, Yangli Zhang, Linguo Xiang, Dan Bai, Li Zhang, Zhi Weng, Ke Lv, Lin Song, Wang Luo, Na Yin, Yaoyi Zhang, Tong Feng, Li Sheng Wang, Guoming Xie

ACS Nano

DOI

2024

A novel entropy-driven dual-output mode integrated with DNAzyme for enhanced microRNA detection

Jianhong Zhang, Dan Bai, Guoming Xie, Yaxing Xie, Yu Lin, Yu‐Lei Hou, Ying Yu, Yaoyi Zhang, Rong Zhao, Zhongzhong Wang, Luojia Wang, Hui Chen

Talanta

DOI

2024

DNA-based molecular classifiers for the profiling of gene expression signatures

Li Zhang, Qian Liu, Yongcan Guo, Luyao Tian, Kena Chen, Dan Bai, Hongyan Yu, Xiaole Han, Wang Luo, Tong Feng, Shixiong Deng, Guoming Xie

Journal of Nanobiotechnology

DOI

2024

Building a stable and robust anti-interference DNA dissipation system by eliminating the accumulation of systemic specified errors

Luojia Wang, Wang Luo, Zhi Weng, Zhongzhong Wang, You Wu, Rong Zhao, Xiaole Han, Xin Liu, Jianhong Zhang, Yujun Yang, Guoming Xie

Analytica Chimica Acta

DOI

2024

Dynamic DNA Assembly by Programmable Hybridization Chain Reaction Mimicking Tubulin

Li Zhang, Yao Fu, Yanqiu Tong, Guoming Xie, Shixiong Deng

Nano Letters

DOI

2023

A Spatially Controlled Proximity Split Tweezer Switch for Enhanced DNA Circuit Construction and Multifunctional Transduction

Dan Bai, Jianhong Zhang, Yaoyi Zhang, Hongyan Yu, Li Zhang, Xiaole Han, Ke Lv, Li Wang, Luo Wang, You Wu, Xi Zhou, Weitao Wang, Tong Feng, Guoming Xie

Small

DOI

2023

Movable toehold for leakless self-assembly circuits

Xiaole Han, Hongyan Yu, Li Zhang, Zhi Weng, Ling Dai, Li Wang, Lin Song, Zhongzhong Wang, Rong Zhao, Luojia Wang, Weitao Wang, Dan Bai, Yongcan Guo, Ke Lv, Guoming Xie

Biosensors and Bioelectronics

DOI

2023

Multifunctional dumbbell probes-based logic circuits: microRNAs logic detection and tumor cells identification

Xin Liu, Baiying Li, Qian Liu, Li Zhang, Rong Zhao, Di Wu, Luojia Wang, Zhongzhong Wang, Guoming Xie, Wenli Feng

Analytica Chimica Acta

DOI

2023

Unmodificated stepless regulation of CRISPR/Cas12a multi-performance

Rong Zhao, Wang Luo, You Wu, Li Zhang, Xin Liu, Junjie Li, Yujun Yang, Li Wang, Luojia Wang, Xiaole Han, Zhongzhong Wang, Jianhong Zhang, Ke Lv, Tingmei Chen, Guoming Xie

Nucleic Acids Research

DOI

2023

Two-point-one-line modularized strategy combined with Holliday-junction button probes for multiloci SNPs long-range distribution analysis

Luo Wang, You Wu, Xueping Chen, Li Zhang, Li Wang, Dan Bai, Qian Liu, Ting Wang, Hongyan Yu, Yaxing Xie, Yixin Fu, Zhongzhong Wang, Yujun Yang, Junjie Li, Yongcan Guo, Ke Lv, Guoming Xie

Chemical Engineering Journal

DOI

2023

Series or parallel toehold-mediated strand displacement and its application in circular RNA detection and logic gates

Shulian Bai, Bangtian Xu, Jiangling Wu, Guoming Xie

Biosensors and Bioelectronics

DOI

2023

RART-LAMP: One-Step Extraction-Free Method for Genotyping within 40 min

Zhang Zhang, Luhao Guan, Juan Yao, Lijia Li, Chunfang Liu, Yongcan Guo, Guoming Xie

Analytical Chemistry

DOI

2023

Enhanced imaging of protein-specific palmitoylation with HCR-based cis-membrane multi-FRET

Yixin Fu, Husun Qian, Yujun Yang, Junjie Li, Guoming Xie

Talanta

DOI

2023

Fluorimetric monitoring of vancomycin using an allosteric probe-initiated sensing platform

Jinshan Yuan, Guoming Xie, Junjie Li, Yaxing Xie, Yuan Yao, Jianhong Zhang, Yu‐Lei Hou, Hui Chen

Analytica Chimica Acta

DOI

2023

A three-site recognition cytosensor based on multi-active AuIrPt polyhedral nanozymes for detection of CTCs

Baiying Li, Huawei Shen, Qian Liu, Xin Liu, Juan Cai, Li Zhang, Di Wu, Yaxing Xie, Guoming Xie, Guoming Xie, Wenli Feng

Sensors and Actuators B Chemical

DOI

2023

A hairpin probe-mediated exponential amplification reaction for highly sensitive and specific detection of microRNAs

Hongyan Yu, Zhi Weng, Xi Zhou, Dan Bai, Wang Luo, Xiaole Han, Lin Song, Qian Liu, Junjie Li, Yujun Yang, Yongcan Guo, Ke Lv, Guoming Xie

Chemical Communications

DOI

2023

Universal probe-based SNP genotyping with visual readout: a robust and versatile method

Zhongzhong Wang, Zhang Zhang, Wang Luo, Luojia Wang, Xiaole Han, Rong Zhao, Xin Liu, Jianhong Zhang, Wen Hao Yu, Junjie Li, Yujun Yang, Zuo Chen, Guoming Xie

Nanoscale

DOI

2022

长链醇类和油类物质洗涤液在磁珠法DNA和RNA共提取中的应用

王鼎，李福刚，罗旺，陈华剑，张珂，谢国明

《检验医学》

2022

A PAM-free CRISPR/Cas12a ultra-specific activation mode based on toehold-mediated strand displacement and branch migration

You Wu, Wang Luo, Zhi Weng, Yongcan Guo, Hongyan Yu, Rong Zhao, Li Zhang, Jie Zhao, Dan Bai, Xi Zhou, Lin Song, Kena Chen, Junjie Li, Yujun Yang, Guoming Xie

Nucleic Acids Research

DOI

2022

A novel fluorescence biosensor based on double-stranded DNA branch migration-induced HCR and DNAzyme feedback circuit for sensitive detection of Pseudomonas aeruginosa (clean version)

Yaxing Xie, Guoming Xie, Jinshan Yuan, Jianhong Zhang, Yujun Yang, Yuan Yao, You Wu, Dan Bai, Kena Chen, Baiying Li, Lin Song, Hui Chen

Analytica Chimica Acta

DOI

2022

Detection of rare CTCs by electrochemical biosensor built on quaternary PdPtCuRu nanospheres with mesoporous architectures

Xi Zhou, Dan Bai, Hongyan Yu, Yixin Fu, Lin Song, You Ping Wu, Kena Chen, Junjie Li, Yujun Yang, Huajian Chen, Zhongzhong Wang, Guoming Xie

Talanta

DOI

2022

Cooperative strand displacement circuit with dual-toehold and bulge-loop structure for single-nucleotide variations discrimination

Dan Bai, Xi Zhou, Wang Luo, Hongyan Yu, Shulian Bai, You Wu, Lin Song, Kena Chen, Yaxing Xie, Xueping Chen, Jie Zhao, Yixin Fu, Yujun Yang, Junjie Li, Guoming Xie

Biosensors and Bioelectronics

DOI

2022

XNA probe and CRISPR/Cas12a-powered flexible fluorescent and electrochemical dual-mode biosensor for sensitive detection of m6A site-specific RNA modification

Qinli Pu, Yuanyuan Ye, Juan Hu, Cong Xie, Xi Zhou, Hongyan Yu, Fangli Liao, Song Jiang, Linshan Jiang, Guoming Xie, Weixian Chen

Talanta

DOI

2022

A Target-Feedback Rolling-Cleavage signal amplifier for ultrasensitive electrochemical detection of miRNA with Self-Assembled CeO2@Ag hybrid nanoflowers

Qian Liu, Huawei Shen, Baiying Li, Juan Cai, Peng Yang, Zhi Weng, Hongyan Yu, Guoming Xie, Wenli Feng

Bioelectrochemistry

DOI

2022

Site-specific insertion of endonuclease recognition sites into amplicons to improve post-PCR analysis sensitivity of gene mutation

Lin Song, Junjie Li, Kena Chen, Zuo Chen, You Wu, Dan Bai, Lin Zhao, Yujun Yang, Chenggui Liu, Guoming Xie

Biosensors and Bioelectronics

DOI

2022

Toehold-mediated nonenzymatic DNA strand displacement coupling UDG mediated PCR and multi-code magnetic beads for DNA genotyping

Zhang Zhang, Zhi Weng, Juan Yao, Dan Liu, Li Zhang, Limei Zhang, Guoming Xie

Microchemical Journal

DOI

2022

Specific and robust hybridization based on double-stranded nucleic acids with single-base resolution

Zhi Weng, Hongyan Yu, Wang Luo, Li Zhang, Zhang Zhang, Ting Wang, Qian Liu, Yongcan Guo, Yujun Yang, Junjie Li, Liu Yang, Ling Dai, Qinli Pu, Xi Zhou, Guoming Xie

Analytica Chimica Acta

DOI

2022

Cooperative Branch Migration: A Mechanism for Flexible Control of DNA Strand Displacement

Zhi Weng, Hongyan Yu, Wang Luo, Yongcan Guo, Qian Liu, Li Zhang, Zhang Zhang, Ting Wang, Ling Dai, Xi Zhou, Xiaole Han, Luojia Wang, Junjie Li, Yujun Yang, Guoming Xie

ACS Nano

DOI

2022

Bulge-loop tuned entropy-driven catalytic reaction and tag-encoded barcodes for multiplexed mutation detection

Wang Luo, Ting Wang, Zhi Weng, Shulian Bai, Li Zhang, You Wu, Hongyan Yu, Dan Bai, Ding Wang, Huajian Chen, Yongcan Guo, Yujun Yang, Junjie Li, Zhang Zhang, Guoming Xie

Sensors and Actuators B Chemical

DOI

2021

Proximity ligation assay mediated rolling circle amplification strategy for in situ amplified imaging of glycosylated PD-L1

Yixin Fu, Husun Qian, Xi Zhou, You Wu, Lin Ye Song, Kena Chen, Dan Bai, Yujun Yang, Junjie Li, Guoming Xie

Analytical and Bioanalytical Chemistry

DOI

2021

DNAzyme based three-way junction assay for antibody-free detection of locus-specific N6-methyladenosine modifications

Hongyan Yu, Qinli Pu, Zhi Weng, Xi Zhou, Junjie Li, Yujun Yang, Wang Luo, Yongcan Guo, Huajian Chen, Ding Wang, Guoming Xie

Biosensors and Bioelectronics

DOI

2021

An electrochemical biosensor based on hemin/G-quadruplex DNAzyme and PdRu/Pt heterostructures as signal amplifier for circulating tumor cells detection

Xi Zhou, Qinli Pu, Hongyan Yu, Peng Yang, Junjie Li, Yujun Yang, Huajian Chen, Yaguang Weng, Guoming Xie

Journal of Colloid and Interface Science

DOI

2021

A comprehensive system for detecting rare single nucleotide variants based on competitive DNA probe and duplex-specific nuclease

Li Zhang, Yufeng Wang, Yongcan Guo, Huajian Chen, Wen Hao Yu, Zhang Zhang, Guoming Xie

Analytica Chimica Acta

DOI

2021

Integration of multiplex PCR and CRISPR-Cas allows highly specific detection of multidrug-resistant Acinetobacter Baumannii

Yufeng Wang, Yongcan Guo, Li Zhang, Yujun Yang, Shuangshuang Yang, Yang Liu, Huajian Chen, Chenggui Liu, Junjie Li, Guoming Xie

Sensors and Actuators B Chemical

DOI

2021

Recent advances of electrochemical sensors for detecting and monitoring ROS/RNS

Shuang Zhao, Guangchao Zang, Yuchan Zhang, Huawen Liu, Nan Wang, Shangjun Cai, Colm Durkan, Guoming Xie, Guixue Wang

Biosensors and Bioelectronics

DOI

2021

An enzyme-powered, three-dimensional lame DNA walker

Jie Fang, Changjing Yuan, Junjie Li, Jun‐Long Li, Tingyan Yang, Yongcan Guo, Ding Wang, Jianjiang Xue, Weiling Fu, Guoming Xie

Biosensors and Bioelectronics

DOI

2021

Fast detection of E. coli with a novel fluorescent biosensor based on a FRET system between UCNPs and GO@Fe 3 O 4 in urine specimens

Yuan Yao, Guoming Xie, Xin Zhang, Jinshan Yuan, Yu‐Lei Hou, Hui Chen

Analytical Methods

DOI

2021

A nanoprobe for fluorescent monitoring of microRNA and targeted delivery of drugs

Zuo Chen, Yongcan Guo, Junjie Li, Zhiping Peng, Shulian Bai, Shuangshuang Yang, Ding Wang, Hui Chen, Guoming Xie

RSC Advances

DOI

2021

Xeno nucleic acid probes mediated methylation-specific PCR for single-base resolution analysis of N 6 -methyladenosine in RNAs

Qinli Pu, Hongyan Yu, Xi Zhou, Junjie Li, Yujun Yang, Ting Wang, Fugang Li, Shangchun Sheng, Guoming Xie

The Analyst

DOI

2020

Ultrasensitive electrochemical biosensor for attomolar level detection of let 7a based on toehold mediated strand displacement reaction circuits and molecular beacon mediated circular strand displacement polymerization

Zhang Zhang, Li Zhang, Youqiang Wang, Juan Yao, Ting Wang, Zhi Weng, Liu Yang, Guoming Xie

Analytica Chimica Acta

DOI

2020

A dual recognition strategy for accurate detection of CTCs based on novel branched PtAuRh trimetallic nanospheres

Juan Cai, Huawei Shen, Yonghong Wang, Peng Yang, Sitian Tang, Yalin Zhu, Qian Liu, Baiying Li, Guoming Xie, Wenli Feng

Biosensors and Bioelectronics

DOI

2020

An integrated fluorescence biosensor for microRNA detection based on exponential amplification reaction-triggered three-dimensional bipedal DNA walkers

Liu Yang, Jie Fang, Junjie Li, Xinying Ou, Li Zhang, Yufeng Wang, Zhi Weng, Guoming Xie

Analytica Chimica Acta

DOI

2020

Simulation-guided DNAzyme based nanomachine design for identifying single nucleotide variants

Li Zhang, Zhang Zhang, Xinying Ou, Yufeng Wang, Liu Yang, Zhi Weng, Guoming Xie

Sensors and Actuators B Chemical

DOI

2020

A novel fluorescence biosensor for the detection and imaging of tumor-related mRNA in living cells based on Au//hGNPs-FA nanocarrier

Huawei Shen, Liyu Liu, Yan Ran, Lu Ma, Ming Zhang, Liyan Qin, Li Zhang, Guoming Xie, Wenli Feng

Sensors and Actuators B Chemical

DOI

2020

PdIrBP mesoporous nanospheres combined with superconductive carbon black for the electrochemical determination and collection of circulating tumor cells

Peng Yang, Yuhang Peng, Sitian Tang, Huawei Shen, Shangchun Sheng, Yonghong Wang, Teng Wang, Juan Cai, Guoming Xie, Wenli Feng

Microchimica Acta

DOI

2020

A fluorometric assay for rapid enrichment and determination of bacteria by using zirconium-metal organic frameworks as both capture surface and signal amplification tag

Shuangshuang Yang, Yongcan Guo, Jingchuan Fan, Yujun Yang, Zuo Chen, Shulian Bai, Shangchun Sheng, Junjie Li, Guoming Xie

Microchimica Acta

DOI

2020

Tuning the specificity of DNA probes using bulge-loops for low-abundance SNV detection

Shulian Bai, Bangtian Xu, Yangli Zhang, Yuhong Zhang, Hao Dang, Shuangshuang Yang, Zuo Chen, Li Zhang, Junjie Li, Guoming Xie

Biosensors and Bioelectronics

DOI

2020

Multiplex real-time PCR using double-strand primers and probes for the detection of nucleic acids

Zhang Zhang, Juan Yao, Xiaoling Huang, Li Zhang, Ting Wang, Zhi Weng, Guoming Xie

Analytical Methods

DOI

2019

Electrochemical competitive immunodetection of messenger RNA modified with N6-methyladenosine by using DNA-modified mesoporous PtCo nanospheres

Xinying Ou, Qinli Pu, Shangchun Sheng, Tao Dai, Dan Gou, Wen Hao Yu, Tingyan Yang, Ling Dai, Yujun Yang, Guoming Xie

Microchimica Acta

DOI

2019

Graphdiyne-Based One-Step DNA Fluorescent Sensing Platform for the Detection of Mycobacterium tuberculosis and Its Drug-Resistant Genes

Fan Chang, Lijun Huang, Chaozhong Guo, Guoming Xie, Jiaqiang Li, Qizhi Diao

ACS Applied Materials & Interfaces

DOI

2019

Fluorometric determination of microRNA by using an entropy-driven three-dimensional DNA walking machine based on a catalytic hairpin assembly reaction on polystyrene microspheres

Tingyan Yang, Jie Fang, Yongcan Guo, Shangchun Sheng, Qinli Pu, Li Zhang, Xinying Ou, Ling Dai, Guoming Xie

Microchimica Acta

DOI

2019

A novel enzyme-free electrochemical biosensor for rapid detection of Pseudomonas aeruginosa based on high catalytic Cu-ZrMOF and conductive Super P

Xin Zhang, Guoming Xie, Dan Gou, Peng Luo, Yuan Yao, Hui Chen

Biosensors and Bioelectronics

DOI

2019

Specific discrimination and universal signal amplification for RNA detection by coupling toehold exchange with RCA through nucleolytic conversion of a structure-switched hairpin probe

Wen Hao Yu, Juqiong Li, Zuo Chen, Yiyi Tao, Shulian Bai, Jun‐Long Li, Zhang Zhang, Guoming Xie

Analytica Chimica Acta

DOI

2019

Simultaneous colorimetric determination of acute myocardial infarction biomarkers by integrating self-assembled 3D gold nanovesicles into a multiple immunosorbent assay

Qinli Pu, Xuanhua Yang, Yongcan Guo, Tao Dai, Tingyan Yang, Xinying Ou, Jun‐Long Li, Shangchun Sheng, Guoming Xie

Microchimica Acta

DOI

2018

便携式血糖仪对耐甲氧西林金黄色葡萄球菌mecA基因的灵敏检测方法研究

方杰，余文，陶一一，代涛，袁长婧，杨宇君，唐兰，谢国明

《分析仪器》

2018

Voltammetric immunoassay for Mycobacterium tuberculosis secretory protein MPT64 based on a synergistic amplification strategy using rolling circle amplification and a gold electrode modified with graphene oxide, Fe3O4 and Pt nanoparticles

Dan Gou, Guoming Xie, Yuxia Li, Xin Zhang, Hui Chen

Microchimica Acta

DOI

2018

A target-triggered biosensing platform for detection of HBV DNA based on DNA walker and CHA

Feng Tao, Jie Fang, Yongcan Guo, Yiyi Tao, Xinle Han, Yuxin Hu, Jinjing Wang, Luyuan Li, Yulin Jian, Guoming Xie

Analytical Biochemistry

DOI

2018

Portable and sensitive detection of DNA based on personal glucose meters and nanogold-functionalized PAMAM dendrimer

Jie Fang, Yongcan Guo, Yujun Yang, Wen Hao Yu, Yiyi Tao, Tao Dai, Changjing Yuan, Guoming Xie

Sensors and Actuators B Chemical

DOI

2018

Analogous modified DNA probe and immune competition method-based electrochemical biosensor for RNA modification

Tao Dai, Qinli Pu, Yongcan Guo, Zuo Chen, Shulian Bai, Yujun Yang, Dan Yin, Yi Li, Shangchun Sheng, Yiyi Tao, Jie Fang, Wen Hao Yu, Guoming Xie

Biosensors and Bioelectronics

DOI

2018

A novel cytosensor based on Pt@Ag nanoflowers and AuNPs/Acetylene black for ultrasensitive and highly specific detection of Circulating Tumor Cells

Sitian Tang, Huawei Shen, Yixiong Hao, Zhenglan Huang, Yiyi Tao, Peng Yang, Yongcan Guo, Guoming Xie, Wenli Feng

Biosensors and Bioelectronics

DOI

2018

High-Discrimination Factor Nanosensor Based on Tetrahedral DNA Nanostructures and Gold Nanoparticles for Detection of MiRNA-21 in Live Cells

Shulian Bai, Bangtian Xu, Yongcan Guo, Juhui Qiu, Wen Hao Yu, Guoming Xie

Theranostics

DOI

2017

基于DNA-AuNPs信号放大的肠出血性大肠埃希菌快速检测电化学生物传感器

陈中平，李俊龙，余文，王箭，邹正渝，汪婷，谢国明

《分析仪器》

2017

基于多孔铂纳米球的白细胞介素-8超灵敏检测电化学免疫传感方法研究

李丽娜，蒲勤丽，何荣，李俊龙，谢国明，石继飞

《分析仪器》

2017

Enzyme Functionalized AuNPs and Glucometer-based Protein Detection

Tao Dai, Jie Fang, Wen Hao Yu, Guoming Xie

IOP Conference Series Materials Science and Engineering

DOI

2017

A new biosensor based on the recognition of phages and the signal amplification of organic-inorganic hybrid nanoflowers for discriminating and quantitating live pathogenic bacteria in urine

Yuxia Li, Guoming Xie, Juhui Qiu, Dandan Zhou, Dan Gou, Yiyi Tao, Yi Li, Hui Chen

Sensors and Actuators B Chemical

DOI

2017

An “off-on” fluorescent switch assay for microRNA using nonenzymatic ligation-rolling circle amplification

Yi Li, Qinli Pu, Jun‐Long Li, Lili Zhou, Yiyi Tao, Yuxia Li, Wen Hao Yu, Guoming Xie

Microchimica Acta

DOI

2017

Cascade toehold-mediated strand displacement along with non-enzymatic target recycling amplification for the electrochemical determination of the HIV-1 related gene

Dan Yin, Yiyi Tao, Lan Tang, Wei Li, Zhang Zhang, Jun‐Long Li, Guoming Xie

Microchimica Acta

DOI

2017

Double-loop hairpin probe and doxorubicin-loaded gold nanoparticles for the ultrasensitive electrochemical sensing of microRNA

Yiyi Tao, Dan Yin, Mingchao Jin, Jie Fang, Tao Dai, Yi Li, Yuxia Li, Qinli Pu, Guoming Xie

Biosensors and Bioelectronics

DOI

2017

Universal ratiometric electrochemical biosensing platform based on mesoporous platinum nanocomposite and nicking endonuclease assisted DNA walking strategy

Qinli Pu, Jun‐Long Li, Juhui Qiu, Xuanhua Yang, Yi Li, Dan Yin, Xinyuan Zhang, Yiyi Tao, Shangchun Sheng, Guoming Xie

Biosensors and Bioelectronics

DOI

2017

A universal electrochemical biosensor for the highly sensitive determination of microRNAs based on isothermal target recycling amplification and a DNA signal transducer triggered reaction

Lili Zhou, Jian Wang, Zhongping Chen, Jun‐Long Li, Ting Wang, Zhang Zhang, Guoming Xie

Microchimica Acta

DOI

2017

Hollow Au loaded with kanamycin for pharmacological and laser-triggered photothermal sterilization

Xing Zhang, Yuxia Li, Juhui Qiu, Dandan Zhou, Minghao Zhang, Lan Tang, Guoming Xie, Hua Xiang

RSC Advances

DOI

2016

心脏生物标志物肌红蛋白的生物传感检测方法

余文，刘灵芝，谢国明

《分析仪器》

2016

A universal probe design for colorimetric detection of single-nucleotide variation with visible readout and high specificity

Xueping Chen, Dandan Zhou, Huawei Shen, Hui Chen, Wenli Feng, Guoming Xie

Scientific Reports

DOI

2016

A fluorescence biosensor for VEGF detection based on DNA assembly structure switching and isothermal amplification

Jun‐Long Li, Kexin Sun, Zhongping Chen, Jifei Shi, Dandan Zhou, Guoming Xie

Biosensors and Bioelectronics

DOI

2016

A novel colorimetric biosensor for detecting target DNA and human alpha thrombin based on associative toehold activation concatemer induced catalyzed hairpin assembly amplification

Shulian Bai, Ting Wang, Zhang Zhang, Shangchun Sheng, Wen Hao Yu, Guoming Xie

Sensors and Actuators B Chemical

DOI

2016

Colorimetric determination of staphylococcal enterotoxin B via DNAzyme-guided growth of gold nanoparticles

Dandan Zhou, Guoming Xie, Xianqing Cao, Xueping Chen, Xing Zhang, Hui Chen

Microchimica Acta

DOI

2016

An electrochemical biosensor for double-stranded Wnt7B gene detection based on enzymatic isothermal amplification

Jun‐Long Li, Zhongping Chen, Yu Xiang, Lili Zhou, Ting Wang, Zhang Zhang, Kexin Sun, Dan Yin, Yi Li, Guoming Xie

Biosensors and Bioelectronics

DOI

2016

Electrochemical immunoassay for the cancer marker LMP-1 (Epstein-Barr virus-derived latent membrane protein 1) using a glassy carbon electrode modified with Pd@Pt nanoparticles and a nanocomposite consisting of graphene sheets and MWCNTs

Xing Zhang, Dandan Zhou, Shangchun Sheng, Juan Yang, Xueping Chen, Guoming Xie, Hua Xiang

Microchimica Acta

DOI

2016

A novel label-free and reusable electrochemical cytosensor for highly sensitive detection and specific collection of CTCs

Huawei Shen, Juan Yang, Zhongping Chen, Xueping Chen, Li Wang, Jing Hu, Feihu Ji, Guoming Xie, Wenli Feng

Biosensors and Bioelectronics

DOI

2015

Energy driven cascade recognition for selective detection of nucleic acids with high discrimination factor at room temperature

Zhang Zhang, Jun long Li, Juan Yao, Ting Wang, Dan Yin, Yu Xiang, Zhongping Chen, Guoming Xie

Biosensors and Bioelectronics

DOI

2015

Ultraspecific electrochemical DNA biosensor by coupling spontaneous cascade DNA branch migration and dual-signaling sensing strategy

Ting Wang, Lili Zhou, Shulian Bai, Zhang Zhang, Jun‐Long Li, Xiaoying Jing, Guoming Xie

Biosensors and Bioelectronics

DOI

2015

Electrochemical Determination of 16s Ribosomal RNA of Mycobacterium Tuberculosis Using Magnetite on Silica with DNA-Functionalized Gold Nanoparticles

Shangchun Sheng, L.-Z. Liu, Zhaohui Zhao, Miao Cai, Xiong Jiang, Yi Kang, Qiong Dai, LU Xin-min, Guoming Xie

Analytical Letters

DOI

2015

A novel platform for high sensitivity determination of PbP2a based on gold nanoparticles composited graphitized mesoporous carbon and doxorubicin loaded hollow gold nanospheres

Juan Yang, Huawei Shen, Xing Zhang, Yiyi Tao, Hua Xiang, Guoming Xie

Biosensors and Bioelectronics

DOI

2015

Quadruple signal amplification strategy based on hybridization chain reaction and an immunoelectrode modified with graphene sheets, a hemin/G-quadruplex DNAzyme concatamer, and alcohol dehydrogenase: ultrasensitive determination of influenza virus subtype H7N9

Juan Yang, Yu Xiang, Chao Song, L.-Z. Liu, Xiaoying Jing, Guoming Xie, Hua Xiang

Microchimica Acta

DOI

2015

Coupling a universal DNA circuit with graphene sheets/polyaniline/AuNPs nanocomposites for the detection of BCR/ABL fusion gene

Xueping Chen, Li Wang, Shangchun Sheng, Teng Wang, Juan Yang, Guoming Xie, Wenli Feng

Analytica Chimica Acta

DOI

2015

Proximity-based electrochemical biosensor for highly sensitive determination of methyltransferase activity using gold nanoparticle-based cooperative signal amplification

Zhang Zhang, Shangchun Sheng, Xianqing Cao, Yiyan Li, Juan Yao, Ting Wang, Guoming Xie

Microchimica Acta

DOI

2015

Amplified electrochemical detection of mecA gene in methicillin-resistant Staphylococcus aureus based on target recycling amplification and isothermal strand-displacement polymerization reaction

Ting Wang, Zhang Zhang, Yiyan Li, Guoming Xie

Sensors and Actuators B Chemical

DOI

2015

Ultrasensitive electrochemical detection of microRNA-21 combining layered nanostructure of oxidized single-walled carbon nanotubes and nanodiamonds by hybridization chain reaction

L.-Z. Liu, Chao Song, Zhang Zhang, Juan Yang, Lili Zhou, Xing Zhang, Guoming Xie

Biosensors and Bioelectronics

DOI

2015

Discussion about Procalcitonin in the Diagnosis of Blood Stream Infection

Xiaoying Jing, Ting Wang, Guoming Xie

2015

MecA Resistant Gene Detection Based on Biosensor

Ting Wang, Zhang Zhang, Guoming Xie

2014

Direct detection of microRNA-126 at a femtomolar level using a glassy carbon electrode modified with chitosan, graphene sheets, and a poly(amidoamine) dendrimer composite with gold and silver nanoclusters

L.-Z. Liu, Shuting Jiang, Li Wang, Zhang Zhang, Guoming Xie

Microchimica Acta

DOI

2014

Target-induced aptamer release strategy based on electrochemical detection of staphylococcal enterotoxin B using GNPs-ZrO2-Chits film

Renni Deng, Li Wang, Guangzhao Yi, Erhui Hua, Guoming Xie

Colloids and Surfaces B Biointerfaces

DOI

2014

DNA-based hybridization chain reaction for an ultrasensitive cancer marker EBNA-1 electrochemical immunosensor

Chao Song, Guoming Xie, Li Wang, L.-Z. Liu, Guang Tian, Hua Xiang

Biosensors and Bioelectronics

DOI

2014

DNA-AuNPs based signal amplification for highly sensitive detection of DNA methylation, methyltransferase activity and inhibitor screening

Xiaoying Jing, Xianqing Cao, Li Wang, Tian Lan, Yiyan Li, Guoming Xie

Biosensors and Bioelectronics

DOI

2014

Ultrasensitive Electrochemical Biosensor for the Detection of the mecA Gene Sequence in Methicillin Resistant Strains of Staphylococcus aureus Employing Gold Nanoparticles

Min Liu, Hua Xiang, Erhui Hua, Li Wang, Xiaoying Jing, Xianqing Cao, Shangchun Sheng, Guoming Xie

Analytical Letters

DOI

2013

基于石墨烯及室温离子液体的弓形虫IgM抗体免疫传感器的研制

陈中平，蒋姝婷，张名均，谢国明

《分析仪器》

2013

基于微机械电子系统的电化学电极阵列的研制

赵朝辉，王力，甘先云，朱昌安，刘成桂，郑军，谢国明

《分析化学》

2013

金标免疫层析法测定唾液中丙型肝炎病毒抗体的研究

梁脉，张名均，谢国明

《国际检验医学杂志》

2013

Aptamer biosensor for sensitive detection of toxin A of Clostridium difficile using gold nanoparticles synthesized by Bacillus stearothermophilus

Peng Luo, Yi Liu, Yun Xia, Huajian Xu, Guoming Xie

Biosensors and Bioelectronics

DOI

2013

Graphene sheets, polyaniline and AuNPs based DNA sensor for electrochemical determination of BCR/ABL fusion gene with functional hairpin probe

Li Wang, Erhui Hua, Mo Liang, Cuixia Ma, Zhangling Liu, Shangchun Sheng, Min Liu, Guoming Xie, Wenli Feng

Biosensors and Bioelectronics

DOI

2013

Electrochemical determination of BCR/ABL fusion gene based on in situ synthesized gold nanoparticles and cerium dioxide nanoparticles

Shenfeng Li, Li Wang, Yajuan Li, Xiaoying Zhu, Liang Zhong, Lingsong Lu, Wei Zhang, Bei Liu, Guoming Xie, Wenli Feng

Colloids and Surfaces B Biointerfaces

DOI

2013

MultisHRP-DNA-coated CMWNTs as signal labels for an ultrasensitive hepatitis C virus core antigen electrochemical immunosensor

Cuixia Ma, Mo Liang, Li Wang, Hua Xiang, Yingtao Jiang, Yiyan Li, Guoming Xie

Biosensors and Bioelectronics

DOI

2013

One-step fabrication of integrated disposable biosensor based on ADH/NAD+/meldola's blue/graphitized mesoporous carbons/chitosan nanobiocomposite for ethanol detection

Erhui Hua, Li Wang, Xiaoying Jing, Changtao Chen, Guoming Xie

Talanta

DOI

2013

Sandwich Immunoassay for Hepatitis C Virus Non-Structural 5A Protein Using a Glassy Carbon Electrode Modified with an Au-MoO3/Chitosan Nanocomposite

Mo Liang, Li Wang, Cuixia Ma, Mingjun Zhang, Guoming Xie

Analytical Letters

DOI

2012

基于石墨烯及CeO2-Au的一次性弓形虫IgM抗体免疫传感器

蒋姝婷，陈中平，刁奇智，盛尚春，谢国明，张名均，徐华建

《化学学报》

2012

A novel immunosensor for detecting toxoplasma gondii-specific IgM based on goldmag nanoparticles and graphene sheets

Shuting Jiang, Erhui Hua, Mo Liang, Bei Liu, Guoming Xie

Colloids and Surfaces B Biointerfaces

DOI

2012

Label-free sandwich type of immunosensor for hepatitis C virus core antigen based on the use of gold nanoparticles on a nanostructured metal oxide surface

Cuixia Ma, Guoming Xie, Wei Zhang, Mo Liang, Bei Liu, Hua Xiang

Microchimica Acta

DOI

2012

Au/CeO2–chitosan composite film for hydrogen peroxide sensing

Wei Zhang, Guoming Xie, Shenfeng Li, Lingsong Lu, Bei Liu

Applied Surface Science

DOI

2012

Detection of the human prostate-specific antigen using an aptasensor with gold nanoparticles encapsulated by graphitized mesoporous carbon

Bei Liu, Lingsong Lu, Erhui Hua, Shuting Jiang, Guoming Xie

Microchimica Acta

DOI

2012

Ultrasensitive electrochemical immunosensor for HE4 based on rolling circle amplification

Lingsong Lu, Bei Liu, Zhaohui Zhao, Cuixia Ma, Peng Luo, Chenggui Liu, Guoming Xie

Biosensors and Bioelectronics

DOI

2012

Elevated Serum Myeloperoxidase Activities are Significantly Associated with the Prevalence of ACS and High LDL-C Levels in CHD Patients

Chenggui Liu, Guoming Xie, Wenfang Huang, Yongchang Yang, Pu Li, Zhiguang Tu

Journal of Atherosclerosis and Thrombosis

DOI

2012

Disposable Amperometric Immunosensor for Detecting Toxoplasma Gondii-Specific IgM Based on Graphene and CeO2-Au

Shuting Jiang, Zhongping Chen, Qizhi Diao, Shangchun Sheng, Guoming Xie, Mingjun Zhang, Huajian Xu

《化学学报》

DOI

2011

A novel microassay for measuring blood alcohol concentration using a disposable biosensor strip

Shenghang Zhen, Yan Wang, Chenggui Liu, Guoming Xie, Chaoshi Zou, Jun Zheng, Yang Zhu

Forensic Science International，Vol. 207, No. 13

DOI

2011

电化学极化玻碳电极构建的葡萄糖生物传感器

张伟，甄生航，谢国明，刁奇智，罗鹏，郑军

《传感器与微系统》

2011

基于PoPD-MWCNTs-离子液体/纳米金的髓过氧化物酶免疫传感器

刘蓓，逯岭松，刘成桂，谢国明

《化学学报》

2011

基于碳纳米管修饰玻碳电极的唾液sIgA可再生免疫传感器

王艳，甄生航，朱洋，谢国明

《分析测试学报》

2011

Hydrogen peroxide biosensor based on gold nanoparticles/thionine/gold nanoparticles/multi-walled carbon nanotubes–chitosans composite film-modified electrode

Shenfeng Li, Xiaoying Zhu, Wei Zhang, Guoming Xie, Wenli Feng

Applied Surface Science

DOI

2011

A New Immunosensor for Serum Myeloperoxidase Based on Self-Assembly of Multi-Walled Carbon Nanotubes/Thionine/Gold Nanoparticles-Chitosan

Qi Diao, Yuan Li, Mi Zhou, Guoming Xie

Advanced materials research

DOI

2011

Improved electrochemical immunosensor for myeloperoxidase in human serum based on nanogold/cerium dioxide-BMIMPF6/l-Cysteine composite film

Lingsong Lu, Bei Liu, Shenfeng Li, Wei Zhang, Guoming Xie

Colloids and Surfaces B Biointerfaces

DOI

2011

Disposable electrochemical immunosensor for myeloperoxidase based on the indium tin oxide electrode modified with an ionic liquid composite film containing gold nanoparticles, poly(o-phenylenediamine) and carbon nanotubes

Bei Liu, Lingsong Lu, Qiong Li, Guoming Xie

Microchimica Acta

DOI

2011

Renewable Salivary Secretory Immunoglobulin A (sIgA) Immunosensor Based on Carbon Nanotube Modified Glassy Carbon Electrode

Guoming Xie

Journal of Instrumental Analysis

2010

基于多壁碳纳米管的三电极血乙醇生物传感器的研究

甄生航，郑军，邹超世，王艳，朱洋，邓世雄，谢国明，王箭

《分析化学》

2010

一种新型唾液sIgA电流型纳米免疫生物传感器的制备

王艳，甄生航，郑军，马霄，刘成桂，朱洋，谢国明

《传感器与微系统》

2010

Amperometric Immunosensor for Myeloperoxidase in Human Serum Based on a Multi-wall Carbon Nanotubes-Ionic Liquid-Cerium Dioxide Film-modified Electrode

Lingsong Lu, Bei Liu, Chenggui Liu, Guoming Xie

Bulletin of the Korean Chemical Society

DOI

2010

Homogeneous competitive assay of ligand affinities based on quenching fluorescence of tyrosine/tryptophan residues in a protein via Főrster-resonance-energy-transfer

Yanling Xie, Xiaolan Yang, Jun Pu, Yunsheng Zhao, Ying Zhang, Guoming Xie, Jun Zheng, Huidong Yuan, Fei Liao

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy

DOI

2010

An alpha-Amylase Biosensor with 1,1-Dimethyl-3-(2-Amino-1-Hydroxyethyl) Ferrocene as an Electron Transfer Mediator

Jun Zheng, Guoming Xie, Changtao Chen

International Conference on Bioinformatics and Biomedical Engineering

DOI

2010

Preparation of a novel salivary sIgA amperometric nano-immunosensor

Guoming Xie

Transducer and Microsystem Technologies

2009

MWNTs与GNPs-CHIT修饰的过氧化氢生物传感器

马霄，谢国明，周觅，邹超世，王艳，甄生航

《传感器与微系统》

2009

血清髓过氧化物酶电流型免疫传感器的研究

周觅，谢国明，邹超世，马霄，熊兴良，罗鹏，刘成桂，郑军

《分析化学》

2009

Homogeneous noncompetitive assay of protein via Förster-resonance-energy-transfer with tryptophan residue(s) as intrinsic donor(s) and fluorescent ligand as acceptor

Fei Liao, Yanling Xie, Xiaolan Yang, Ping Deng, Yiwen Chen, Guoming Xie, Sha Zhu, Beizhong Liu, Huidong Yuan, Juan Liao, Yunsheng Zhao, Mingan Yu

Biosensors and Bioelectronics

DOI

2008

Determination of serum alcohol using a disposable biosensor

Peng Luo, Yi Liu, Guoming Xie, Xingliang Xiong, Shixiong Deng, Fangzhou Song

Forensic Science International，Vol. 179, No. 23

DOI

2008

一次性唾液α-淀粉酶生物传感器的研制

邹超世，周觅，谢国明，罗鹏，熊兴良，徐华健，郑军

《分析化学》

2008

Nafion-二茂铁修饰的脑疲劳检测生物传感器的研究

周觅，邹超世，谢国明，罗鹏，熊兴良，郑军

《传感器与微系统》

2008

An integration strategy to estimate the initial rates of enzyme reactions with much expanded linear ranges using uricases as models

Beizhong Liu, Yunsheng Zhao, Lina Zhao, Yanlin Xie, Sha Zhu, Zhirong Li, Yin Liu, Wei Lü, Xiaolan Yang, Guoming Xie, Huansi Zhong, Mingan Yu, Hong Liao, Fei Liao

Analytica Chimica Acta

DOI

2008

Preparation of Disposable Saliva α-Amylase Biosensor

Chao-Shi ZOU, Mi ZHOU, Guoming Xie, Peng LUO, Xingliang Xiong, Huajian Xu, Jun Zheng

Chinese Journal of Analytical Chemistry

DOI

2008

Electrochemical detection of blood alcohol concentration using a disposable biosensor based on screen-printed electrode modified with Nafion and gold nanoparticles

Peng Luo, Guoming Xie, Yi Liu, Huajian Xu, Shixiong Deng, Fangzhou Song

Clinical Chemistry and Laboratory Medicine (CCLM)

DOI

2007

麦尔多拉蓝作为电子介体的一次性血清酒精生物传感器

罗鹏，谢国明，宋方洲，邓世雄，徐华健

《分析化学》

2006

临床检验中的生物传感器

谢国明，熊兴良，郑军，李琼，罗鹏

《分子诊断与治疗杂志》

精选作品

期刊论文

HPMES: an ultra-sensitive mutation enrichment strategy for FLT3-ITD MRD monitoring in acute myeloid leukemia

Bioinspired Compartmentalization Coupled with DNA-Gated Magnetic Nanoprobes Enables Simultaneous Electrochemical Detection of Dual MicroRNAs

Input-Triggered Allosteric Activation of CRISPR–Cas12a by Modular Loop-Engineered Hairpins

CAMERA: A programmable CRISPR-gated logic system for high-fidelity assessment of Mycobacterium tuberculosis

A structural accessibility principle for LbuCas13a activation by noncontiguous DNA

Programmable pH-responsive DNA inter-strand matching (PRISM) for precision molecular band-pass actuation

A spatiotemporally separated recognition–amplification strategy based on an M13 phage biological lever for immunodetection of bacteria

Dephosphorylation-regulated MNAzyme-PER cascade as a programmable converter for multi-task molecular actuation

Hairpin-Mediated TMSDR-CHA Signal Conversion for Highly Specific Single-Base Discrimination of EGFR L858R Mutation

Detachable TMSD-CRISPR for programmable and highly specific discrimination of DNA/RNA mutations

A universal and orthogonal safety valve for CRISPR/Cas12a without chemical modification or external stimulation

An aptamer-mediated EXPAR fluorescence biosensor for early and sensitive detection of Aβ42 and Aβ40

Rational design of CRISPR–Cas12a crRNAs for enhanced allelic discrimination and low-abundance variant detection

A DNAzyme-CRISPR cascade strategy for preamplification-free detection of Mycobacterium tuberculosis

OS11.7.A IMAGING OF MOLECULAR BOUNDARIES IN GLIOBLASTOMAUSING PROGRAMMABLE PH-RESPONSIVE DNA NANOPROBES

Rational design of tunable pH switches through shadow-strand hybridization-actuated displacement engineering

A dual-antibody sandwich immunoassay using upconversion nanoparticles and magnetic beads for fibrinogen detection

Click Chemistry-Accelerated DNA Strand Displacement Reaction

Design of mismatch closure for enhanced specificity in DNA strand displacement reactions

Ultra-sensitive detection of complex SNVs via allele-specific dPCR enhanced by multi-strand displacement reaction

Smart Energy-Storing DNA Hydrogel for On-Demand Laser-Free Photoimmunotherapy of Melanoma

Triple-Layer locked nanodevice synergizes with Pd@PdPtRh nanozyme and 3D conductive nanocomplex for ultrasensitive dual-miRNA electrochemical biosensing

Regulation of CRISPR trans-cleavage activity by an overhanging activator

Logical Analysis of Multiple miRNAs with Isothermal Molecular Classifiers Based on LATE-RCA

Engineering thermostable fluorescent DNA aptamer for the isothermal amplification of nucleic acids

Specific fluorescence detection strategy for single-stranded nucleic acids by dual-toehold branch migration

Dynamic Time-Programming Circuit for Encoding Information, Programming Dissipative Systems, and Delaying Release of Cargo

A phage amplification-assisted SEA-CRISPR/Cas12a system for viable bacteria detection

Sequence-Unconstrained DNA Computing: DSN cycling and PER circuitry for dynamic miRNAs analysis and multifunctional logic operations

Allosteric stem-loop multicomponent DNAzyme: A versatile stimuli-responsive switch for nanotweezer operations and multifunctional biosensing

Design of enhanced entropy-driven non-covalent DNA catalytic reactions via the paired junction structure

Three-way junction-mediated three-letter coded SDA cascade CRISPR/Cas12a system for circRNA detection

AND Logic-Gate-Based Dual-Locking Probe System for the Sensitive Detection of microRNA and APE1

Modified Unit-Mediated Strand Displacement Reactions for Direct Detection of Single Nucleotide Variants in Active Double-Stranded DNA

A novel entropy-driven dual-output mode integrated with DNAzyme for enhanced microRNA detection

DNA-based molecular classifiers for the profiling of gene expression signatures

Building a stable and robust anti-interference DNA dissipation system by eliminating the accumulation of systemic specified errors

Dynamic DNA Assembly by Programmable Hybridization Chain Reaction Mimicking Tubulin

A Spatially Controlled Proximity Split Tweezer Switch for Enhanced DNA Circuit Construction and Multifunctional Transduction

Movable toehold for leakless self-assembly circuits

Multifunctional dumbbell probes-based logic circuits: microRNAs logic detection and tumor cells identification

Unmodificated stepless regulation of CRISPR/Cas12a multi-performance

Two-point-one-line modularized strategy combined with Holliday-junction button probes for multiloci SNPs long-range distribution analysis

Series or parallel toehold-mediated strand displacement and its application in circular RNA detection and logic gates

RART-LAMP: One-Step Extraction-Free Method for Genotyping within 40 min

Enhanced imaging of protein-specific palmitoylation with HCR-based cis-membrane multi-FRET

Fluorimetric monitoring of vancomycin using an allosteric probe-initiated sensing platform

A three-site recognition cytosensor based on multi-active AuIrPt polyhedral nanozymes for detection of CTCs

A hairpin probe-mediated exponential amplification reaction for highly sensitive and specific detection of microRNAs

Universal probe-based SNP genotyping with visual readout: a robust and versatile method

长链醇类和油类物质洗涤液在磁珠法DNA和RNA共提取中的应用

A PAM-free CRISPR/Cas12a ultra-specific activation mode based on toehold-mediated strand displacement and branch migration

A novel fluorescence biosensor based on double-stranded DNA branch migration-induced HCR and DNAzyme feedback circuit for sensitive detection of Pseudomonas aeruginosa (clean version)

Detection of rare CTCs by electrochemical biosensor built on quaternary PdPtCuRu nanospheres with mesoporous architectures

Cooperative strand displacement circuit with dual-toehold and bulge-loop structure for single-nucleotide variations discrimination

XNA probe and CRISPR/Cas12a-powered flexible fluorescent and electrochemical dual-mode biosensor for sensitive detection of m6A site-specific RNA modification

A Target-Feedback Rolling-Cleavage signal amplifier for ultrasensitive electrochemical detection of miRNA with Self-Assembled CeO2@Ag hybrid nanoflowers

Site-specific insertion of endonuclease recognition sites into amplicons to improve post-PCR analysis sensitivity of gene mutation

Toehold-mediated nonenzymatic DNA strand displacement coupling UDG mediated PCR and multi-code magnetic beads for DNA genotyping

Specific and robust hybridization based on double-stranded nucleic acids with single-base resolution

Cooperative Branch Migration: A Mechanism for Flexible Control of DNA Strand Displacement

Bulge-loop tuned entropy-driven catalytic reaction and tag-encoded barcodes for multiplexed mutation detection

Proximity ligation assay mediated rolling circle amplification strategy for in situ amplified imaging of glycosylated PD-L1

DNAzyme based three-way junction assay for antibody-free detection of locus-specific N6-methyladenosine modifications

An electrochemical biosensor based on hemin/G-quadruplex DNAzyme and PdRu/Pt heterostructures as signal amplifier for circulating tumor cells detection

A comprehensive system for detecting rare single nucleotide variants based on competitive DNA probe and duplex-specific nuclease

Integration of multiplex PCR and CRISPR-Cas allows highly specific detection of multidrug-resistant Acinetobacter Baumannii

Recent advances of electrochemical sensors for detecting and monitoring ROS/RNS

An enzyme-powered, three-dimensional lame DNA walker

Fast detection of E. coli with a novel fluorescent biosensor based on a FRET system between UCNPs and GO@Fe 3 O 4 in urine specimens

A nanoprobe for fluorescent monitoring of microRNA and targeted delivery of drugs

Xeno nucleic acid probes mediated methylation-specific PCR for single-base resolution analysis of N 6 -methyladenosine in RNAs

Ultrasensitive electrochemical biosensor for attomolar level detection of let 7a based on toehold mediated strand displacement reaction circuits and molecular beacon mediated circular strand displacement polymerization

A dual recognition strategy for accurate detection of CTCs based on novel branched PtAuRh trimetallic nanospheres

An integrated fluorescence biosensor for microRNA detection based on exponential amplification reaction-triggered three-dimensional bipedal DNA walkers

Simulation-guided DNAzyme based nanomachine design for identifying single nucleotide variants

A novel fluorescence biosensor for the detection and imaging of tumor-related mRNA in living cells based on Au//hGNPs-FA nanocarrier

PdIrBP mesoporous nanospheres combined with superconductive carbon black for the electrochemical determination and collection of circulating tumor cells