侯晓明｜东北农业大学｜学者主页

2026

Methionine promotes cell proliferation in bovine mammary epithelial cells via the ATF4-GSK3β signalling pathway

Yanying Zhang, Yalin Xie, Meiyan Liu, Fengxian Sui, Jing Gao, Jiadi Su, Yang Yang, Ye Lin, Xiaoming Hou, Na Zhang

Journal of Dairy Research

DOI

2026

Oxidative stress inhibits milk fat production by p38 MAPK-Cebpα-Acsl6 axis in mouse mammary gland

Xiaoxue Wang, Jiadi Su, Jing Gao, Meiyan Liu, Fengxian Sui, Yalin Xie, Zhihui Wang, Ye Lin, Yang Yang, Xiaoming Hou

Free Radical Biology and Medicine

DOI

2026

NRF2-CD36 Axis-Mediated Oleic Acid-Induced Milk Fat Production in Dairy Cow Mammary Epithelial Cells

Caiyan Zhang, Fengxian Sui, Meiyan Liu, Yalin Xie, Jiadi Su, Jing Gao, Ye Lin, Yang Yang, Xiaoming Hou

Journal of Agricultural and Food Chemistry

DOI

2025

CD146基因参与乙酸钠对奶牛乳腺上皮细胞乳脂合成的调节

徐自如，葛慧聚，刘佳琪，随风贤，刘美妍，杨洋，侯晓明，林叶

《东北农业大学学报》

2024

MMP23B对奶牛乳腺上皮细胞乳脂合成影响的研究

王波，谢佳秀，孙宇，邢鹏飞，杨洋，侯晓明，林叶

《东北农业大学学报》

DOI

2024

GPR37L1对奶牛乳腺上皮细胞乳成分合成相关基因表达的影响

邢鹏飞，王晓雪，王智慧，谢雅琳，杨洋，侯晓明，林叶

《东北农业大学学报》

2024

Leptin signaling promotes milk fat synthesis via PI3K/AKT/mTOR/SREBP1 in mammary gland of dairy cow

Yang� Yang, Zhihui Wang, Haixia Ge, Bo Wang, Pengfei Xing, Nan Wang, Zhiyi Song, Ye Lin, Xiaoming Hou

Journal of Dairy Research

DOI

2024

Prolactin upregulates amino acid uptake in dairy cow mammary epithelial cells via LAT1

Xiaoming Hou, Shuyuan Song, Ziru Xu, Ying Shi, Yang Yang, Li Zhang, Yingjun Cui, Chunmei Wang, Ye Lin

Journal of Dairy Science

DOI

2024

PI3K/AKT/mTORC1 signalling pathway regulates MMP9 gene activation via transcription factor NF-κB in mammary epithelial cells of dairy cows

Yongjin Mao, Su Chen, Huilin Yang, Xiaocong Ma, Feng Zhao, Bo Qu, Yang Yang, Xiaoming Hou, Bing Zhao, Yingjun Cui

Animal Biotechnology

DOI

2024

Transcriptomic analysis reveals that prolactin modulates the β-casein synthesis mechanism in bovine mammary epithelial cells

Yanying Zhang, Ziru Xu, Xiaoxue Wang, Xiaoming Hou, Yang Yang, Ying Liu, Ye Lin

Journal of Dairy Research

DOI

2023

mTORC2‐AKT‐LAT1 signalling participates in methionine‐induced β‐CASEIN expression in mammary epithelial cells of dairy cows

Xiaoyu Duan, Chuanping Liu, Xiaoqing Gong, Yang Yang, Hongtao Jiao, Ye Lin, Xiaoming Hou

Journal of Animal Physiology and Animal Nutrition

DOI

2023

Acetate Upregulates GPR43 Expression and Function via PI3K-AKT-SP1 Signaling in Mammary Epithelial Cells during Milk Fat Synthesis

Yang Yang, Chuanping Liu, Caiyan Zhang, Ziru Xu, Li Zhang, Yingjun Cui, Chunmei Wang, Ye Lin, Xiaoming Hou

Journal of Agricultural and Food Chemistry

DOI

2022

AGPAT6在奶牛乳腺上皮细胞乳脂合成中的功能研究

林叶，刘灿，江怡，宫晓庆，刘川萍，杨洋，侯晓明

《东北农业大学学报》

2022

mTOR信号通路介导短链脂肪酸调控PLIN3表达促进乳脂合成

侯晓明，江怡，刘灿，杨洋，张金友

《东北农业大学学报》

2022

奶牛SP1基因结构及对乳脂合成功能的初步分析

杨洋，周子薇，张京一，杨硕，王博宇，葛楠，林叶，侯晓明

《畜牧兽医学报》

2022

PPARγ-AGPAT6 signaling mediates acetate-induced mTORC1 activation and milk fat synthesis in mammary epithelial cells of dairy cows

Can Liu, Chuanping Liu, Xiaoqing Gong, Yi Hua Jiang, Yang Yang, Jinyou Zhang, Xiaoming Hou, Ye Lin

Journal of Dairy Research

DOI

2021

Cell death-inducing DNA fragmentation factor-α-like effector C (CIDEC) regulates acetate- and β-hydroxybutyrate-induced milk fat synthesis by increasing FASN expression in mammary epithelial cells of dairy cows

He Lv, Qingyu Meng, Nan Wang, Xiaoyu Duan, Xiaoming Hou, Ye Lin

Journal of Dairy Science

DOI

2020

奶牛乳腺中4F2hc基因的表达模式及亮氨酸对其表达的调控研究

姜明慧，黄鹤，段晓宇，江怡，刘灿，侯晓明

《中国畜牧兽医》

DOI

2020

Prolactin regulates LAT1 expression via STAT5 (signal transducer and activator of transcription 5) signaling in mammary epithelial cells of dairy cows

Jinyu Zhou, Minghui Jiang, Ying Shi, Shuyuan Song, Xiaoming Hou, Ye Lin

Journal of Dairy Science

DOI

2020

Controlled synchronization of prolactin/STAT5 and AKT1/mTOR in bovine mammary epithelial cells

Baosheng Wang, Linlin Shi, Jingjing Men, Qingzhang Li, Xiaoming Hou, Chunmei Wang, Feng Zhao

In Vitro Cellular & Developmental Biology - Animal

DOI

2020

Examination of methionine stimulation of gene expression in dairy cow mammary epithelial cells using RNA-sequencing

Xiaoming Hou, Minghui Jiang, Jinyu Zhou, Shuyuan Song, Feng Zhao, Ye Lin

Journal of Dairy Research

DOI

2020

Laminin-dependent integrin β1 signaling regulates milk protein synthesis via prolactin/STAT5 pathway in bovine mammary epithelial cells

Baosheng Wang, Jingjing Men, Chunmei Wang, Xiaoming Hou, Feng Zhao

Biochemical and Biophysical Research Communications

DOI

2020

Nutrigenomic Role of Acetate and β-Hydroxybutyrate in Bovine Mammary Epithelial Cells

Shuyuan Song, Minghui Jiang, Jinyu Zhou, Feng Zhao, Xiaoming Hou, Ye Lin

DNA and Cell Biology

DOI

2019

Functional analysis of the dairy cow mammary transcriptome between early lactation and mid-dry period

Ye Lin, He Lv, Minghui Jiang, Jinyu Zhou, Shuyuan Song, Xiaoming Hou

Journal of Dairy Research

DOI

2018

奶牛乳脂合成及其影响因素

吕贺，段晓宇，周金玉，宋书媛，姜明慧，侯晓明，林叶

《中国畜牧兽医》

2018

FABP5 is a critical regulator of methionine‐ and estrogen‐induced SREBP‐1c gene expression in bovine mammary epithelial cells

Ping Li, Mengmeng Yu, Chengjian Zhou, Hao Qi, Xue‐Peng Wen, Xiaoming Hou, Meng Li, Xuejun Gao

Journal of Cellular Physiology

DOI

2017

采用四引物ARMS-PCR方法检测奶牛乳腺组织DGAT1基因单核苷酸多态性

段晓宇，吕贺，杨洋，矫洪涛，侯晓明，林叶

《中国畜牧兽医》

2017

The effects of L-type amino acid transporter 1 on milk protein synthesis in mammary glands of dairy cows

Ye Lin, Xiaoyu Duan, He Lv, Yang Yang, Ying Liu, Xuejun Gao, Xiaoming Hou

Journal of Dairy Science

DOI

2017

Methionine Induces LAT1 Expression in Dairy Cow Mammary Gland by Activating the mTORC1 Signaling Pathway

Xiaoyu Duan, Ye Lin, He Lv, Yang Yang, Hongtao Jiao, Xiaoming Hou

DNA and Cell Biology

DOI

2017

The effects of cell death-inducing DNA fragmentation factor-α-like effector C (CIDEC) on milk lipid synthesis in mammary glands of dairy cows

Yang Yang, Ye Lin, Xiaoyu Duan, He Lv, Weinan Xing, Qingzhang Li, Xuejun Gao, Xiaoming Hou

Journal of Dairy Science

DOI

2016

L型氨基酸转运载体1对奶牛乳腺中β-酪蛋白表达的影响

邢伟楠，段晓宇，杨洋，侯晓明，林叶

《中国畜牧兽医》

2016

Effects of glucose on lactose synthesis in mammary epithelial cells from dairy cow

Ye Lin, Xiaoxu Sun, Xiaoming Hou, Bo Qu, Xuejun Gao, Qingzhang Li

BMC Veterinary Research

DOI

2016

The effect of G protein-coupled receptor kinase 2 (GRK2) on lactation and on proliferation of mammary epithelial cells from dairy cows

Xiaoming Hou, Hongliu Hu, Ye Lin, Bo Qu, Xuejun Gao, Qingzhang Li

Journal of Dairy Science

DOI

2016

Spleen tyrosine kinase regulates mammary epithelial cell proliferation in mammary glands of dairy cows

Xiaoming Hou, Lin Lin, Weinan Xing, Yang Yang, Xiaoyu Duan, Qingzhang Li, Xuejun Gao, Ye Lin

Journal of Dairy Science

DOI

2015

脾源性酪氨酸激酶基因在奶牛乳腺中的表达研究

林琳，范会全，邢伟楠，杨洋，侯晓明，张常顺，林叶

《中国畜牧兽医》

2015

Thyroid hormone responsive protein spot 14 enhances lipogenesis in bovine mammary epithelial cells

Yingjun Cui, Zhiyu Liu, Xia Sun, Xiaoming Hou, Bo Qu, Feng Zhao, Xuejun Gao, Zhe Sun, Qingzhang Li

In Vitro Cellular & Developmental Biology - Animal

DOI

2014

必需氨基酸上调乳腺腺泡中L型氨基酸转运载体1的表达

林叶，侯晓明，田雷，齐帮若，李庆章

《中国畜牧兽医》

2014

甲硫氨酸对奶牛乳腺上皮细胞中酪蛋白生物合成的调控

林叶，侯晓明

《中国畜牧杂志》

2014

L型氨基酸转运载体1及其配体在奶牛乳腺中的协同表达研究

林叶，侯晓明

《畜牧兽医学报》

2014

Pten对奶牛乳腺上皮细胞活力及乳蛋白合成的影响

王卓然，侯晓明，曲波，王杰，高学军，李庆章

《中国生物化学与分子生物学报》

2014

油酸和硬脂酸对奶牛乳腺上皮细胞中脂肪酸结合蛋白3表达和脂滴分泌的影响

梁梦瑶，高学军，侯晓明，李庆章

《中国畜牧兽医》

2014

小鼠乳腺发育泌乳过程中L型氨基酸转运载体1的表达研究

林叶，胡红柳，侯晓明

《中国畜牧兽医》

2014

Pten Regulates Development and Lactation in the Mammary Glands of Dairy Cows

Zhuoran Wang, Xiaoming Hou, Bo Qu, Jie Wang, Xuejun Gao, Qingzhang Li

PLoS ONE

DOI

2014

Functional analysis of FABP3 in the milk fat synthesis signaling pathway of dairy cow mammary epithelial cells

Mengyao Liang, Xiaoming Hou, Bo Qu, Na Zhang, Nan Li, Yingjun Cui, Qingzhang Li, Xuejun Gao

In Vitro Cellular & Developmental Biology - Animal

DOI

2013

脂肪酸结合蛋白3在乳脂合成信号转导通路中的研究进展

梁梦瑶，高学军，李庆章，侯晓明

《中国畜牧兽医》

2013

泌乳奶牛乳腺中LAT1和4F2hc的表达定位研究

林叶，侯晓明，李庆章，田雷，闫宏博，李春，黄田英

《中国乳品工业》

2012

高通量基因表达谱的应用

胡红柳，侯晓明，曲波，高学军，李庆章

《中国乳品工业》

2010

泌乳期奶牛乳腺基因表达谱研究

侯晓明，李庆章，黄田英

《中国科学:生命科学》

2010

乳腺中JAK-STAT信号通路的研究进展

黄田英，李庆章，侯晓明

《中国乳品工业》

2010

Microarray analysis of gene expression profiles in the bovine mammary gland during lactation

Xiaoming Hou, Qingzhang Li, Tianying Huang

Science China Life Sciences

DOI

2010

Progress on JAK-STAT Function in mammary gland

Tianying Huang, LI Qing-zhang, Xiaoming Hou

Zhongguo rupin gongye

2009

奶牛乳腺发育及泌乳重要功能基因的筛选

侯晓明

《东北农业大学》

2008

小鼠乳腺细胞凋亡及瘦素对凋亡的影响

侯晓明，李庆章

《中国实验动物学报》

2006

乳腺细胞凋亡及其研究进展

侯晓明，李庆章

《中国乳品工业》

精选作品

期刊论文

Methionine promotes cell proliferation in bovine mammary epithelial cells via the ATF4-GSK3β signalling pathway

Oxidative stress inhibits milk fat production by p38 MAPK-Cebpα-Acsl6 axis in mouse mammary gland

NRF2-CD36 Axis-Mediated Oleic Acid-Induced Milk Fat Production in Dairy Cow Mammary Epithelial Cells

CD146基因参与乙酸钠对奶牛乳腺上皮细胞乳脂合成的调节

MMP23B对奶牛乳腺上皮细胞乳脂合成影响的研究

GPR37L1对奶牛乳腺上皮细胞乳成分合成相关基因表达的影响

Leptin signaling promotes milk fat synthesis via PI3K/AKT/mTOR/SREBP1 in mammary gland of dairy cow

Prolactin upregulates amino acid uptake in dairy cow mammary epithelial cells via LAT1

PI3K/AKT/mTORC1 signalling pathway regulates MMP9 gene activation via transcription factor NF-κB in mammary epithelial cells of dairy cows

Transcriptomic analysis reveals that prolactin modulates the β-casein synthesis mechanism in bovine mammary epithelial cells

mTORC2‐AKT‐LAT1 signalling participates in methionine‐induced β‐CASEIN expression in mammary epithelial cells of dairy cows

Acetate Upregulates GPR43 Expression and Function via PI3K-AKT-SP1 Signaling in Mammary Epithelial Cells during Milk Fat Synthesis

AGPAT6在奶牛乳腺上皮细胞乳脂合成中的功能研究

mTOR信号通路介导短链脂肪酸调控PLIN3表达促进乳脂合成

奶牛SP1基因结构及对乳脂合成功能的初步分析

PPARγ-AGPAT6 signaling mediates acetate-induced mTORC1 activation and milk fat synthesis in mammary epithelial cells of dairy cows

Cell death-inducing DNA fragmentation factor-α-like effector C (CIDEC) regulates acetate- and β-hydroxybutyrate-induced milk fat synthesis by increasing FASN expression in mammary epithelial cells of dairy cows

奶牛乳腺中4F2hc基因的表达模式及亮氨酸对其表达的调控研究

Prolactin regulates LAT1 expression via STAT5 (signal transducer and activator of transcription 5) signaling in mammary epithelial cells of dairy cows

Controlled synchronization of prolactin/STAT5 and AKT1/mTOR in bovine mammary epithelial cells

Examination of methionine stimulation of gene expression in dairy cow mammary epithelial cells using RNA-sequencing

Laminin-dependent integrin β1 signaling regulates milk protein synthesis via prolactin/STAT5 pathway in bovine mammary epithelial cells

Nutrigenomic Role of Acetate and β-Hydroxybutyrate in Bovine Mammary Epithelial Cells

Functional analysis of the dairy cow mammary transcriptome between early lactation and mid-dry period

奶牛乳脂合成及其影响因素

FABP5 is a critical regulator of methionine‐ and estrogen‐induced SREBP‐1c gene expression in bovine mammary epithelial cells

采用四引物ARMS-PCR方法检测奶牛乳腺组织DGAT1基因单核苷酸多态性

The effects of L-type amino acid transporter 1 on milk protein synthesis in mammary glands of dairy cows

Methionine Induces LAT1 Expression in Dairy Cow Mammary Gland by Activating the mTORC1 Signaling Pathway

The effects of cell death-inducing DNA fragmentation factor-α-like effector C (CIDEC) on milk lipid synthesis in mammary glands of dairy cows

L型氨基酸转运载体1对奶牛乳腺中β-酪蛋白表达的影响

Effects of glucose on lactose synthesis in mammary epithelial cells from dairy cow

The effect of G protein-coupled receptor kinase 2 (GRK2) on lactation and on proliferation of mammary epithelial cells from dairy cows

Spleen tyrosine kinase regulates mammary epithelial cell proliferation in mammary glands of dairy cows

脾源性酪氨酸激酶基因在奶牛乳腺中的表达研究

Thyroid hormone responsive protein spot 14 enhances lipogenesis in bovine mammary epithelial cells

必需氨基酸上调乳腺腺泡中L型氨基酸转运载体1的表达

甲硫氨酸对奶牛乳腺上皮细胞中酪蛋白生物合成的调控

L型氨基酸转运载体1及其配体在奶牛乳腺中的协同表达研究

Pten对奶牛乳腺上皮细胞活力及乳蛋白合成的影响

油酸和硬脂酸对奶牛乳腺上皮细胞中脂肪酸结合蛋白3表达和脂滴分泌的影响

小鼠乳腺发育泌乳过程中L型氨基酸转运载体1的表达研究

Pten Regulates Development and Lactation in the Mammary Glands of Dairy Cows

Functional analysis of FABP3 in the milk fat synthesis signaling pathway of dairy cow mammary epithelial cells

脂肪酸结合蛋白3在乳脂合成信号转导通路中的研究进展

泌乳奶牛乳腺中LAT1和4F2hc的表达定位研究

高通量基因表达谱的应用

泌乳期奶牛乳腺基因表达谱研究

乳腺中JAK-STAT信号通路的研究进展

Microarray analysis of gene expression profiles in the bovine mammary gland during lactation

Progress on JAK-STAT Function in mammary gland

奶牛乳腺发育及泌乳重要功能基因的筛选

小鼠乳腺细胞凋亡及瘦素对凋亡的影响

乳腺细胞凋亡及其研究进展

会议论文

The effects of SYK on proliferation and lactation in mammary epithelial cells of dairy cows

奶牛乳腺上皮细胞核泌乳相关磷酸化蛋白质组学分析

Pten基因对奶牛乳腺上皮细胞泌乳的调节功能

Thrsp对奶牛乳腺上皮细胞泌乳功能的影响及其作用机理研究

脾源性酪氨酸激酶基因过表达对奶牛乳腺上皮细胞增殖的影响

乳腺不同发育时期的miRNA表达图谱

研究方向