贺冬秀｜南华大学｜学者主页

2026

线粒体靶向纳米制剂在癌症免疫治疗中的研究进展

蔡嘉，黄红武，彭丙枞，唐嘉锶，谢培康，陈湘钰，贺冬秀

《药学学报》

2026

Copper-Based Nanoparticle Co-Loaded with Natural PD-L1 Inhibitor and 5-Fluorouracil for Enhanced Immunotherapy of Hepatocellular Carcinoma

Hongwu Huang, Bingcong Peng, Xinyu Zhao, Xiangyu Chen, Dongxiu He

Molecular Pharmaceutics

DOI

2025

Mitochondria-Targeted Nanoformulations: New Therapeutic Strategies and Opportunities for Cancer Immunotherapy

Jia Cai, Hongwu Huang, Bingcong Peng, Jiasi Tang, Dongxiu He

Current Drug Targets

DOI

2024

Nrf2: A critical participant in regulation of apoptosis, ferroptosis, and autophagy in gastric cancer

LiJie Tang, Dongxiu He, Bo Su

Acta Histochemica

DOI

2024

Carrier-free nanoparticles based on self-assembly of 5-FU and copper-genistein complexes for the combined treatment of hepatocellular carcinoma

Siwei Chen, Hongwu Huang, Qi Li, Jia Cai, Zhuolin Miao, Peikang Xie, Shengsong Tang, Dongxiu He

Drug Delivery and Translational Research

DOI

2024

Cisplatin-Based Combination Therapy for Enhanced Cancer Treatment

Qi Li, Siwei Chen, Xiao Wang, Jia Cai, Hongwu Huang, Shengsong Tang, Shengsong Tang, Dongxiu He

Current Drug Targets

DOI

2023

不同来源外泌体在肝癌诊断与治疗中的研究进展

任展志，麻瑶瑶，石玉群，陈思维，贺冬秀

《现代肿瘤医学》

2023

Functions and targets of miRNAs in pharmacological and toxicological effects of major components of Tripterygium wilfordii Hook F

Wei Pan, Bo Yang, Dongxiu He, Linxi Chen, Chengxiao Fu

Naunyn-Schmiedeberg s Archives of Pharmacology

DOI

2023

A Sodium Alginate‐Based Multifunctional Nanoplatform for Synergistic Chemo‐Immunotherapy of Hepatocellular Carcinoma

Cong Huang, Ting Xie, Yufeng Liu, Shuang Yan, Feijun Ouyang, Haitao Zhang, Longtianyang Lei, Dongxiu He, Hua Wei, Cui‐Yun Yu

Advanced Materials

DOI

2023

A Clinically Translatable Ternary Platinum(IV) Prodrug for Synergistically Reversing Drug Resistance

Ying Liu, Dun Wang, Hongbing Liu, Li Liu, Shuang Li, Zongtao Zhou, Linyin Lu, Xuyue Liu, Lifang He, Dongxiu He, Cui‐Yun Yu, Hua Wei

Journal of Medicinal Chemistry

DOI

2022

Prolonged blood circulation outperforms active targeting for nanocarriers-mediated enhanced hepatocellular carcinoma therapy in vivo

Yueqing Wang, Cong Huang, Peng-Ju Ye, Jinrong Long, Chenghu Xu, Ying Liu, Xiaoli Ling, Shaoyang Lv, Dongxiu He, Hua Wei, Cui‐Yun Yu

Journal of Controlled Release

DOI

2022

Functionalized PAMAM-based Nanoformulation for Targeted Delivery of 5-Fluorouracil in Hepatocellular Carcinoma

Siwei Chen, Hu Ouyang, Dongxiu He, Daquan Liu, Xiao Wang, Hong‐Yuan Chen, Wei Pan, Qi Li, Weiquan Xie, Cui‐Yun Yu

Current Pharmaceutical Design

DOI

2021

改性聚酰胺-胺树枝状大分子用于肿瘤治疗的研究进展

陈思维，欧阳湖，刘大权，王肖，何健，贺冬秀

《肿瘤学杂志》

2021

核酸适配体修饰聚酰胺-胺负载5-氟尿嘧啶纳米给药体系的制备表征及体外抗肝癌作用

欧阳湖，宁玲，陈思维，贺冬秀，王肖，何健，谢伟全

《中南医学科学杂志》

DOI

2021

Functionalized PAMAM-Based system for targeted delivery of miR-205 and 5-fluorouracil in breast cancer

Qian Jun Tang, Daquan Liu, Hong‐Yuan Chen, Dongxiu He, Wei Pan, Qi Li, Weiquan Xie, Siwei Chen, Cui‐Yun Yu

Journal of Drug Delivery Science and Technology

DOI

2021

Design, synthesis, and biological evaluation of 3′,4′,5′‐trimethoxy evodiamine derivatives as potential antitumor agents

Yijiao Peng, Runde Xiong, Zhen Li, Junmei Peng, Zhizhong Xie, Xiaoyong Lei, Dongxiu He, Guotao Tang

Drug Development Research

DOI

2020

Facile Fabrication of Nanoparticles with Dual-Targeting Ligands for Precise Hepatocellular Carcinoma Therapy In Vitro and In Vivo

Ya Xiang, Wen Huang, Cong Huang, Jinrong Long, Yangchun Zhou, Yufeng Liu, Si-Yue Tang, Dongxiu He, Xiangwen Tan, Hua Wei, Cui‐Yun Yu

Molecular Pharmaceutics

DOI

2019

多肽介导的给药系统在肝癌靶向治疗中的研究进展

王梦梦，王欢，欧阳湖，杜珊，吴舒蕾，陈思维，贺冬秀

《肿瘤学杂志》

2019

MicroRNA-based potential diagnostic, prognostic and therapeutic applications in triple-negative breast cancer

Qian Tang, Hu Ouyang, Dongxiu He, Cui‐Yun Yu, Guotao Tang

Artificial Cells Nanomedicine and Biotechnology

DOI

2019

Delivery of Liver-Specific miRNA-122 Using a Targeted Macromolecular Prodrug toward Synergistic Therapy for Hepatocellular Carcinoma

Qian Ning, Yufeng Liu, Peng-Ju Ye, Pei Gao, Zhiping Li, Si-Yue Tang, Dongxiu He, Shengsong Tang, Hua Wei, Cui‐Yun Yu

ACS Applied Materials & Interfaces

DOI

2019

Cell Membrane-Camouflaged Nanoparticles as Drug Carriers for Cancer Therapy

Cheng‐Hui Xu, Peng-Ju Ye, Yangchun Zhou, Dongxiu He, Hua Wei, Cui‐Yun Yu

Acta Biomaterialia

DOI

2019

Design, synthesis and biological evaluation of tryptamine salicylic acid derivatives as potential antitumor agents

Runde Xiong, Dongxiu He, Xiangping Deng, Juan Liu, Xiaoyong Lei, Zhizhong Xie, Xuan Cao, Yan-Ming Chen, Junmei Peng, Guotao Tang

MedChemComm

DOI

2018

叶酸修饰聚酰胺-胺负载5-氟尿嘧啶纳米给药体系的制备及其体外性能研究

汤芊，史晓欣，贺冬秀，熊润德，唐国涛

《南华大学学报(自然科学版)》

2018

Fabrication and characterization of a novel self-assembling micelle based on chitosan cross-linked pectin–doxorubicin conjugates macromolecular pro-drug for targeted cancer therapy

Zhiping Li, Ming-Chao Jiang, Bo Chen, Pei Gao, Sa Yang, Yufeng Liu, Peng-Ju Ye, Dongxiu He, Honglin Huang, Cui‐Yun Yu

RSC Advances

DOI

2018

Fabrication and characterization of a folic acid-bound 5-fluorouracil loaded quantum dot system for hepatocellular carcinoma targeted therapy

Xiaoxin Shi, Dongxiu He, Guotao Tang, Qian Tang, Runde Xiong, Hu Ouyang, Cui‐Yun Yu

RSC Advances

DOI

2015

功能化量子点在生物分析,生物成像和靶向运输中的应用（英文）

贺冬秀，王丹霞，全文捷，喻翠云

《中南医学科学杂志》

2015

半乳糖化壳聚糖—氟尿嘧啶偶合物纳米给药体系的制备、表征及体外性能研究

李娜梅，杨飒，宁倩，黄灿，黄文，贺子宁，贺冬秀，喻翠云

《南华大学学报(自然科学版)》

2015

Fabrication of galactosylated chitosan–5‐fluorouracil acetic acid based nanoparticles for controlled drug delivery

Cui‐Yun Yu, Na‐Mei Li, Sa Yang, Qian Ning, Can Huang, Wen Huang, Zi‐Ning He, Dongxiu He, Xiangwen Tan, Lichun Sun

Journal of Applied Polymer Science

DOI

2014

In Vitro and in Vivo Evaluation of Pectin-Based Nanoparticles for Hepatocellular Carcinoma Drug Chemotherapy

Cui‐Yun Yu, Yanmei Wang, Na‐Mei Li, Ge-Sha Liu, Sa Yang, Guotao Tang, Dongxiu He, Xiangwen Tan, Hua Wei

Molecular Pharmaceutics

DOI

2013

载药果胶基纳米粒子体外HepG2肝癌细胞的靶向性研究

王彦妹，李娜梅，刘格莎，贺冬秀，唐国涛，雷小勇，严奉祥，喻翠云

《南华大学学报(自然科学版)》

2011

聚乙二醇化聚酰胺-胺树枝状材料的制备及其细胞毒性研究

唐国涛，曹轩，刘瑞，喻翠云，贺冬秀，郭玉

《中南医学科学杂志》

2011

聚酰胺—胺树枝状高分子/喜树碱复合物的制备及体外释放研究

唐国涛，曹轩，贺冬秀，陈临溪，喻翠云

《南华大学学报(自然科学版)》

2011

水溶性CdTe量子点荧光探针检测肠癌相关T抗原

贺冬秀，刘璐，许光明，陈波

《中国科学:化学》

2011

CdTe量子点制备及其在癌相关物质检测与药物研究中的应用

贺冬秀

《湖南师范大学》

2010

水溶性CdTe量子点荧光猝灭法测定尼群地平的研究

贺冬秀，刘璐，喻翠云，何小珍

《分析测试学报》

2010

CdTe量子点荧光猝灭法测定尼群地平的研究

贺冬秀，卢亚玲，刘露，陈波

《南华大学学报(自然科学版)》

贺冬秀

精选作品

期刊论文

线粒体靶向纳米制剂在癌症免疫治疗中的研究进展

Copper-Based Nanoparticle Co-Loaded with Natural PD-L1 Inhibitor and 5-Fluorouracil for Enhanced Immunotherapy of Hepatocellular Carcinoma

Mitochondria-Targeted Nanoformulations: New Therapeutic Strategies and Opportunities for Cancer Immunotherapy

Nrf2: A critical participant in regulation of apoptosis, ferroptosis, and autophagy in gastric cancer

Carrier-free nanoparticles based on self-assembly of 5-FU and copper-genistein complexes for the combined treatment of hepatocellular carcinoma

Cisplatin-Based Combination Therapy for Enhanced Cancer Treatment

不同来源外泌体在肝癌诊断与治疗中的研究进展

Functions and targets of miRNAs in pharmacological and toxicological effects of major components of Tripterygium wilfordii Hook F

A Sodium Alginate‐Based Multifunctional Nanoplatform for Synergistic Chemo‐Immunotherapy of Hepatocellular Carcinoma

A Clinically Translatable Ternary Platinum(IV) Prodrug for Synergistically Reversing Drug Resistance

Prolonged blood circulation outperforms active targeting for nanocarriers-mediated enhanced hepatocellular carcinoma therapy in vivo

Functionalized PAMAM-based Nanoformulation for Targeted Delivery of 5-Fluorouracil in Hepatocellular Carcinoma

改性聚酰胺-胺树枝状大分子用于肿瘤治疗的研究进展

核酸适配体修饰聚酰胺-胺负载5-氟尿嘧啶纳米给药体系的制备表征及体外抗肝癌作用

Functionalized PAMAM-Based system for targeted delivery of miR-205 and 5-fluorouracil in breast cancer

Design, synthesis, and biological evaluation of 3′,4′,5′‐trimethoxy evodiamine derivatives as potential antitumor agents

Facile Fabrication of Nanoparticles with Dual-Targeting Ligands for Precise Hepatocellular Carcinoma Therapy In Vitro and In Vivo

多肽介导的给药系统在肝癌靶向治疗中的研究进展

MicroRNA-based potential diagnostic, prognostic and therapeutic applications in triple-negative breast cancer

Delivery of Liver-Specific miRNA-122 Using a Targeted Macromolecular Prodrug toward Synergistic Therapy for Hepatocellular Carcinoma

Cell Membrane-Camouflaged Nanoparticles as Drug Carriers for Cancer Therapy

Design, synthesis and biological evaluation of tryptamine salicylic acid derivatives as potential antitumor agents

叶酸修饰聚酰胺-胺负载5-氟尿嘧啶纳米给药体系的制备及其体外性能研究

Fabrication and characterization of a novel self-assembling micelle based on chitosan cross-linked pectin–doxorubicin conjugates macromolecular pro-drug for targeted cancer therapy

Fabrication and characterization of a folic acid-bound 5-fluorouracil loaded quantum dot system for hepatocellular carcinoma targeted therapy

功能化量子点在生物分析,生物成像和靶向运输中的应用（英文）

半乳糖化壳聚糖—氟尿嘧啶偶合物纳米给药体系的制备、表征及体外性能研究

Fabrication of galactosylated chitosan–5‐fluorouracil acetic acid based nanoparticles for controlled drug delivery

In Vitro and in Vivo Evaluation of Pectin-Based Nanoparticles for Hepatocellular Carcinoma Drug Chemotherapy

载药果胶基纳米粒子体外HepG2肝癌细胞的靶向性研究

聚乙二醇化聚酰胺-胺树枝状材料的制备及其细胞毒性研究

聚酰胺—胺树枝状高分子/喜树碱复合物的制备及体外释放研究

水溶性CdTe量子点荧光探针检测肠癌相关T抗原

CdTe量子点制备及其在癌相关物质检测与药物研究中的应用

水溶性CdTe量子点荧光猝灭法测定尼群地平的研究

CdTe量子点荧光猝灭法测定尼群地平的研究

研究方向