陈玲艳｜上海工程技术大学｜学者主页

2026

Asymmetric Michael Addition of 3-Chlorooxindoles with Vinylidene Bisphosphonates: Synthesis of 3,3-Disubstituted 3-Chlorooxindoles and Spirocyclopropane-Fused Oxindoles

Si-Jia Wan, Yi‐Hu Jin, Ya Li, Youcan Zhang, Ling‐Yan Chen

The Journal of Organic Chemistry

DOI

2026

Enantioselective Michael addition of N -substituted 3-chlorooxindoles with 1,1-bis(arylsulfonyl)ethylenes: access to 3,3-disubstituted and spirocyclopropane-fused oxindoles

Si-Jia Wan, Youcan Zhang, Ling‐Yan Chen, Ya Li

Organic & Biomolecular Chemistry

DOI

2025

DBU‐Mediated Difluoroalkylation of Cyclic Sulfonyl Aldimines with Difluoroenoxysilanes

Yu‐Xi Xing, Hao Zheng, Pei‐Hua Zhao, Chen‐Xin Bao, Ling‐Yan Chen, Ya Li

ChemistrySelect

DOI

2025

Dual-regioselective direct C(sp 2 )-arylation of unprotected β-enamino esters with 2-indolylmethanols catalyzed by Brønsted acid

Qing‐Chun Song, Pei‐Hua Zhao, Yu-Xi Xing, Chen‐Xin Bao, Ling‐Yan Chen, Ya Li

RSC Advances

DOI

2024

Organocatalyzed Asymmetric Michael Addition of 3-Fluorooxindole to Vinylidene Bisphosphonates

Yi‐Hu Jin, Xiaoping Wang, Li-Wen Ning, Ren-Jie Wang, Ya Li, Youcan Zhang, Ling‐Yan Chen

The Journal of Organic Chemistry

DOI

2023

Evans’ Chiral Auxiliary‐Based Asymmetric Synthetic Methodology and Its Modern Extensions

Ling‐Yan Chen, Pei‐Qiang Huang, Pei‐Qiang Huang

European Journal of Organic Chemistry

DOI

2023

Enantioselective Synthesis of Diarylmethylamines through the Aza-Friedel–Crafts Reaction of 1,3,5-Trialkoxy Benzenes and N-Sulfonyl Aldimines Catalyzed by BINOL-Derived Disulfonimides

Zi-Hao Jia, Ling‐Yan Chen, Hao Zheng, Zhang‐Rui Li, Qing‐Chun Song, Ya Li

The Journal of Organic Chemistry

DOI

2023

MeOH‐Mediated Efficient Reduction with N ‐Heterocyclic Carbene Boranes Towards the Synthesis of Cyclic Sulfamates and Sulfonamides

Hao Zheng, Qing‐Chun Song, Ziwen Guan, Zhang‐Rui Li, Ling‐Yan Chen, Ya Li

ChemistrySelect

DOI

2023

Synthesis and neuroprotective activity of a (–)-cytisine-isoflavone conjugate

Li Hua Tang, Ling‐Yan Chen, Zi-Hao Jia, Hao Zheng, Zhang‐Rui Li, Xiaoying Yin

Chemistry of Heterocyclic Compounds

DOI

2022

Discovery and evaluation of cytisine N-isoflavones as novel EGFR/HER2 dual inhibitors

Yanqing Wang, Xiaoying Yin, Ling‐Yan Chen, Zhixiang Yin, Zhicheng Zuo

Bioorganic Chemistry

DOI

2022

Enantioselective synthesis of 2-indolyl methanamine derivatives through disulfonimide-catalyzed Friedel–Crafts C2-alkylation of 3-substituted indoles with imines

Peng Sun, Zi-Hao Jia, Li Hua Tang, Hao Zheng, Zhang‐Rui Li, Ling‐Yan Chen, Ya Li

Organic & Biomolecular Chemistry

DOI

2022

In(OTf) 3 -catalyzed N -α phosphonylation of N , O -acetals with triethyl phosphite

Jian‐Ting Sun, Xin Li, Tianyu Yang, Min Lv, Ling‐Yan Chen, Bang‐Guo Wei

Organic & Biomolecular Chemistry

DOI

2021

二碘化钐促进的2-哌啶酮与α,β-不饱和酸酯的加成-开环反应研究

孙建婷，陈玲艳，魏邦国

《有机化学》

2021

Organo-catalyzed Michael addition of 2-fluoro-2-arylacetonitriles

De‐Yin Chen, Shuai Song, Ling‐Yan Chen, Xinfeng Ren, Ya Li

Tetrahedron Letters

DOI

2021

Asymmetric Synthesis of α‐Amino Acids Bearing a 3‐Alkyloxindole Structural Motif

Xiaoping Wang, Yong‐Liang Liu, Jie Wei, Ling‐Yan Chen, Ya Li

ChemistrySelect

DOI

2021

Synthesis of α‐Amidoacrylates Containing a 3‐Ylideneoxindole Motif

Shuai Song, Ya Li, De‐Yin Chen, Xiaoping Wang, Yong‐Liang Liu, Ling‐Yan Chen

ChemistrySelect

DOI

2020

3-(2,2-Dioxo-3,4-dihydrobenzo[e][1,2,3]oxathiazin-4-yl)-3-fluoro-1-phenylindolin-2-one

Mei-Fang Wu, Ling‐Yan Chen, Ya Li

IUCrData

DOI

2020

Highly diastereoselective aldol reactions of 3-Fluorooxindoles promoted by MgBr2•OEt2/iPr2NEt

Zi‐Bin Qiu, Ling‐Yan Chen, Jian Ji, Xinfeng Ren, Ya Li

Journal of Fluorine Chemistry

DOI

2020

Organocatalytic synthesis of 5‐hydroxyisoxazolidine catalyzed by camphor sulfonyl hydrazines through aza‐Michael addition/cyclization

Fangfang Xu, Ling‐Yan Chen, Peng Sun, Yixin Lv, Yan‐Xue Zhang, Jiayu Li, Xiaoying Yin, Ya Li

Chirality

DOI

2019

Diastereoconvergent synthesis of chiral sulfoxides containing vicinal amino alcohol framework

Yan-Xue Zhang, Ling‐Yan Chen, Bang‐Guo Wei

Tetrahedron Letters

DOI

2019

Visible‐Light Photoredox‐Catalyzed Cross‐Dehydrogenative Coupling of Tetrahydroisoquinolines with 3‐Fluorooxindoles

Jian Ji, Ling‐Yan Chen, Zi‐Bin Qiu, Xinfeng Ren, Ya Li

Asian Journal of Organic Chemistry

DOI

2019

Enantioselective Mannich Reactions of 3-Fluorooxindoles with Cyclic N -Sulfamidate Aldimines

Jianbo Zhao, Ya Li, Ling‐Yan Chen, Xinfeng Ren

The Journal of Organic Chemistry

DOI

2019

MgBr2OEt2-promoted direct Aldol reactions of S-aryl 2-fluoroethanethioate

Zi‐Bin Qiu, Xinfeng Ren, Xiang‐Yu Chen, Ling‐Yan Chen, Jian Ji, Ya Li

Journal of Fluorine Chemistry

DOI

2019

Organocatalytic asymmetric Michael addition between 3-subsituted oxindoles and enals catalyzed by camphor sulfonyl hydrazine

Wen‐Fu Cheng, Ling‐Yan Chen, Fangfang Xu, Wei‐Yu Lin, Xinfeng Ren, Ya Li

Organic & Biomolecular Chemistry

DOI

2018

(S)-4-氨基-1-((S)-1-羟基-3-(4-甲氧基苯基-)2-丙基)吡咯烷-2-腈的合成

姜洁，许顾杰，陈玲艳

《上海工程技术大学学报》

2018

An Efficient Catalytic Amidation of Esters Promoted by N-Heterocyclic Carbenes

Ling‐Yan Chen, Mei-Fang Wu

Synthesis

DOI

2018

Organocatalytic asymmetric syntheses of 3-fluorooxindoles containing vicinal fluoroamine motifs

Bu-quan Zheng, Ling‐Yan Chen, Jianbo Zhao, Jian Ji, Zi‐Bin Qiu, Xinfeng Ren, Ya Li

Organic & Biomolecular Chemistry

DOI

2017

An efficient FeCl 3 -mediated approach for reduction of ketones through N -heterocyclic carbene boranes

Ming-Hui Wang, Ling‐Yan Chen

Tetrahedron Letters

DOI

2015

Asymmetric Reduction of tert-Butanesulfinyl Ketimines by N-Heterocyclic Carbene Boranes

Tao Liu, Ling‐Yan Chen, Zhihua Sun

The Journal of Organic Chemistry

DOI

2015

A Versatile Approach for the Synthesis of Thiobarbiturate Analogues

Xiaokun Zhou, Ling‐Yan Chen, Zhihua Sun

Journal of Heterocyclic Chemistry

DOI

2014

Microwave-Assisted or Cu–NHC-Catalyzed Cycloaddition of Azido-Disubstituted Alkynes: Bifurcation of Reaction Pathways

Yuyu Xia, Ling‐Yan Chen, Shang Lv, Zhihua Sun, Bing Wang

The Journal of Organic Chemistry

DOI

2014

A practical approach for regioselective mono-nitration of phenols under mild conditions

Ling‐Yan Chen, Tao Liu, Xiaokun Zhou, Zhihua Sun

ARKIVOC

DOI

2014

Asymmetric Michael addition of acetone to β-nitrostyrenes catalyzed by novel organocatalysts derived from D-isomannide or L-isoidide

Ling‐Yan Chen, Stéphane Guillarme, Andrew Whiting, Christine Saluzzo

ARKIVOC

DOI

2014

Asymmetric synthesis of stable α-aminoboronic esters catalyzed by N-heterocylic carbene and copper(i) chloride

Jinbo Chen, Ling‐Yan Chen, Yue Zheng, Zhihua Sun

RSC Advances

DOI

2013

Dianhydrohexitols: new tools for organocatalysis. Application in enantioselective Friedel-Crafts alkylation of indoles with nitroalkenes

Ling‐Yan Chen, Stéphane Guillarme, Christine Saluzzo

ARKIVOC

DOI

精选作品

期刊论文

Asymmetric Michael Addition of 3-Chlorooxindoles with Vinylidene Bisphosphonates: Synthesis of 3,3-Disubstituted 3-Chlorooxindoles and Spirocyclopropane-Fused Oxindoles

Enantioselective Michael addition of N -substituted 3-chlorooxindoles with 1,1-bis(arylsulfonyl)ethylenes: access to 3,3-disubstituted and spirocyclopropane-fused oxindoles

DBU‐Mediated Difluoroalkylation of Cyclic Sulfonyl Aldimines with Difluoroenoxysilanes

Dual-regioselective direct C(sp 2 )-arylation of unprotected β-enamino esters with 2-indolylmethanols catalyzed by Brønsted acid

Organocatalyzed Asymmetric Michael Addition of 3-Fluorooxindole to Vinylidene Bisphosphonates

Evans’ Chiral Auxiliary‐Based Asymmetric Synthetic Methodology and Its Modern Extensions

Enantioselective Synthesis of Diarylmethylamines through the Aza-Friedel–Crafts Reaction of 1,3,5-Trialkoxy Benzenes and N-Sulfonyl Aldimines Catalyzed by BINOL-Derived Disulfonimides

MeOH‐Mediated Efficient Reduction with N ‐Heterocyclic Carbene Boranes Towards the Synthesis of Cyclic Sulfamates and Sulfonamides

Synthesis and neuroprotective activity of a (–)-cytisine-isoflavone conjugate

Discovery and evaluation of cytisine N-isoflavones as novel EGFR/HER2 dual inhibitors

Enantioselective synthesis of 2-indolyl methanamine derivatives through disulfonimide-catalyzed Friedel–Crafts C2-alkylation of 3-substituted indoles with imines

In(OTf) 3 -catalyzed N -α phosphonylation of N , O -acetals with triethyl phosphite

二碘化钐促进的2-哌啶酮与α,β-不饱和酸酯的加成-开环反应研究

Organo-catalyzed Michael addition of 2-fluoro-2-arylacetonitriles

Asymmetric Synthesis of α‐Amino Acids Bearing a 3‐Alkyloxindole Structural Motif

Synthesis of α‐Amidoacrylates Containing a 3‐Ylideneoxindole Motif

3-(2,2-Dioxo-3,4-dihydrobenzo[e][1,2,3]oxathiazin-4-yl)-3-fluoro-1-phenylindolin-2-one

Highly diastereoselective aldol reactions of 3-Fluorooxindoles promoted by MgBr2•OEt2/iPr2NEt

Organocatalytic synthesis of 5‐hydroxyisoxazolidine catalyzed by camphor sulfonyl hydrazines through aza‐Michael addition/cyclization

Diastereoconvergent synthesis of chiral sulfoxides containing vicinal amino alcohol framework

Visible‐Light Photoredox‐Catalyzed Cross‐Dehydrogenative Coupling of Tetrahydroisoquinolines with 3‐Fluorooxindoles

Enantioselective Mannich Reactions of 3-Fluorooxindoles with Cyclic N -Sulfamidate Aldimines

MgBr2OEt2-promoted direct Aldol reactions of S-aryl 2-fluoroethanethioate

Organocatalytic asymmetric Michael addition between 3-subsituted oxindoles and enals catalyzed by camphor sulfonyl hydrazine

(S)-4-氨基-1-((S)-1-羟基-3-(4-甲氧基苯基-)2-丙基)吡咯烷-2-腈的合成

An Efficient Catalytic Amidation of Esters Promoted by N-Heterocyclic Carbenes

Organocatalytic asymmetric syntheses of 3-fluorooxindoles containing vicinal fluoroamine motifs

An efficient FeCl 3 -mediated approach for reduction of ketones through N -heterocyclic carbene boranes

Asymmetric Reduction of tert-Butanesulfinyl Ketimines by N-Heterocyclic Carbene Boranes

A Versatile Approach for the Synthesis of Thiobarbiturate Analogues

Microwave-Assisted or Cu–NHC-Catalyzed Cycloaddition of Azido-Disubstituted Alkynes: Bifurcation of Reaction Pathways

A practical approach for regioselective mono-nitration of phenols under mild conditions

Asymmetric Michael addition of acetone to β-nitrostyrenes catalyzed by novel organocatalysts derived from D-isomannide or L-isoidide

Asymmetric synthesis of stable α-aminoboronic esters catalyzed by N-heterocylic carbene and copper(i) chloride

Dianhydrohexitols: new tools for organocatalysis. Application in enantioselective Friedel-Crafts alkylation of indoles with nitroalkenes

预印本

Organocatalytic Substrate-Controlled Regioselective Reactions Of 2‐Indolylmethanols with Phenols And Alcohols Access 3‐Aryl Indoles and Indole-Derived Triaryl Ethers

研究方向