百晓学者学者目录

张燕

山东第一医科大学

精选作品

期刊论文

2026

千金苇茎汤通过调控NF-κB/NLRP3信号通路介导的细胞焦亡途径减轻脓毒症大鼠急性肺损伤的实验研究

陈辉，王培，许骏如，张燕，程峰，周婷婷

《现代免疫学》

2026

三红胡萝卜和香菜介导的氟代芳香酮不对称还原反应

唐允浩，周齐治，王韬，邱智恒，乐效靖，张燕，余金生

《化学学报》

2025

Cryo-EM reveals cholesterol binding in the lysosomal GPCR-like protein LYCHOS

Jie Zhao, Qingya Shen, Xi-Hao Yong, Xin Li, Xiao-Wen Tian, Suyue Sun, Zheng Xu, Xiaoyu Zhang, Luofu Zhang, Hao Yang, Zhenhua Shao, Haoxing Xu, Yi-Yang Jiang, Yan Zhang, Wei Yan

Nature Structural & Molecular Biology

DOI

2024

Conformational transitions and activation of the adhesion receptor CD97.

C. Mao, Rui-Na Zhao, Yingjun Dong, Mingxin Gao, Li-Nan Chen, Chao Zhang, Peng Xiao, Jia Guo, Jiao Qin, D.-D. Shen, Su-Yu Ji, Shaokun Zang, Huibing Zhang, Wei-Wei Wang, Qingya Shen, Jin-Peng Sun, Yan Zhang

Molecules and Cells

DOI

2024

Structural basis of orientated asymmetry in a mGlu heterodimer

Weizhu Huang, Nan Jin, Jia Guo, Cangsong Shen, Chanjuan Xu, Kun Xi, Leo Bonhomme, R. Quast, D.-D. Shen, Jiao Qin, Yi-Ru Liu, Yuxuan Song, Yang Gao, Emmanuel Margeat, P. Rondard, Jean-Philippe Pin, Yan Zhang, Jian-Feng Liu

Nature Communications

DOI

2024

Structural Basis of GPCR-G Protein Pre-coupling and Activation: Insights from CCR1-Gi Complex

Zhe-Hua Shao, Yingjun Dong, Ruixin Jia, Qingya Shen, Bing-Peng Yao, Xinheng He, Qing-Ning Yuan, D.-D. Shen, C. Mao, Chao Zhang, Zhihua Chen, H. E. Xu, Song-Min Ying, Yan Zhang, Wen Li

bioRxiv

DOI

2024

Structural basis of tethered agonism and G protein coupling of protease-activated receptors

Jia Guo, Yun-Li Zhou, Yi-Xin Yang, Shimeng Guo, E. You, Xin Xie, Yi Jiang, C. Mao, H. E. Xu, Yan Zhang

Cell Research

DOI

2024

法莫替丁-对甲苯磺酸共晶的制备表征及性质研究

赵永凤，范莹，张燕，徐红，李敏，杨钊

《中国药学杂志》

2024

3种尼古丁囊泡制剂的制备及体外评价

王慧，邵青，张燕，张玲，吴强驹

《中国新药杂志》

2024

替米沙坦片在中国健康受试者的生物等效性研究

孙成，张燕，房红霞，陈桂英，章晓娟，孙洪勋，姜彬

《中国临床药理学杂志》

2023

Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor

J. Duan, P. Xu, Huibing Zhang, X. Luan, Jiaqi Yang, Xin-Heng He, C. Mao, D. Shen, Yujie Ji, Xi Cheng, Hua-Liang Jiang, Yi Jiang, Shu-Yang Zhang, Yan Zhang, H. E. Xu

Nature Communications

DOI

2023

Orthosteric and allosteric modulation of human HCAR2 signaling complex

C. Mao, Mengru Gao, Shaokun Zang, Yanqing Zhu, D. Shen, Li-Nan Chen, Liu Yang, Zhi-Wei Wang, Huibing Zhang, Wei-Wei Wang, Qingya Shen, Yan-Hui Lu, Xin Ma, Yan Zhang

Nature Communications

DOI

2023

Unsaturated bond recognition leads to biased signal in a fatty acid receptor

C. Mao, P. Xiao, X. Tao, Jiao Qin, Qing-Tao He, Chao Zhang, Sheng-Chao Guo, Ya-Qin Du, Li-Nan Chen, D. Shen, Zhi-Shuai Yang, Han-Qiong Zhang, Shen-ming Huang, Yong-Hao He, Jie Cheng, Y. Zhong, Pan Shang, Jun Chen, Dao-Lai Zhang, Qianli Wang, Mei-Xia Liu, Guo-Yu Li, Yongyuan Guo, H. E. Xu, Chuan Wang, Cheng Zhang, Shiqing Feng, Xiao Yu, Yan Zhang, Jin-Peng Sun

Science

DOI

2023

Snapshot of the cannabinoid receptor 1-arrestin complex unravels the biased signaling mechanism.

Yu-Ying Liao, Huibing Zhang, Qingya Shen, Chenxi Cai, Yu Ding, D.-D. Shen, Jia Guo, Jiao Qin, Yingjun Dong, Yan Zhang, Xiao-Ming Li

Cell

DOI

2023

高效液相色谱法测定血浆万古霉素药物浓度及其药物代谢动力学/药物效应动力学临床应用

张燕，胡琴，胡凯，张颖帆，黄玲，罗荣耀，黄琪

《老年医学研究》

2023

奥拉帕利片在中国成年肿瘤患者中的生物等效性研究

孙成，胡海勋，王孟锦，张燕，姜彬，吕郭金，周宇

《中国临床药理学杂志》

2022

Structural insights into human brain–gut peptide cholecystokinin receptors

Yu Ding, Huibing Zhang, Yu-Ying Liao, Li-Nan Chen, Su-Yu Ji, Jiao Qin, C. Mao, D. Shen, Linda Lin, Hao Wang, Yan Zhang, Xiao-Ming Li

Cell Discovery

DOI

2022

Molecular basis for the activation of thyrotropin-releasing hormone receptor

Su-Yu Ji, Yingjun Dong, Li-Nan Chen, Shaokun Zang, Jiawei Wang, D. Shen, Jia Guo, Jiao Qin, Huibing Zhang, Wen Wang, Q. Shen, Yan Zhang, Zhangfa Song, C. Mao

Cell Discovery

DOI

2022

Structure insights into selective coupling of G protein subtypes by a class B G protein-coupled receptor

Lihua Zhao, Jingyu Lin, Su-Yu Ji, X. E. Zhou, C. Mao, D. Shen, Xin-Heng He, P. Xiao, Jin-Peng Sun, K. Melcher, Yan Zhang, Xiao Yu, H. Xu

Nature Communications

DOI

2022

Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3

Zhe-Hua Shao, Yangxia Tan, Q. Shen, L. Hou, Bing-Peng Yao, Jiao Qin, P. Xu, C. Mao, Li-Nan Chen, Huibing Zhang, D. Shen, Chao Zhang, Weijie Li, Xufei Du, Fei Li, Zhihua Chen, Yi Jiang, H. Xu, Song-Min Ying, Honglei Ma, Yan Zhang, Hua-Hao Shen

Cell Discovery

DOI

2022

Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors

J. Duan, D. Shen, Ting Zhao, Shimeng Guo, Xin-Heng He, W. Yin, P. Xu, Yuqi Ji, Li-Nan Chen, Jinyu Liu, Huibing Zhang, Qiufeng Liu, Yi Shi, Xi Cheng, Hua-Liang Jiang, H. Eric Xu, Yan Zhang, Xin Xie, Yi Jiang

Nature Communications

DOI

2022

Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors

F. Zhao, Qingtong Zhou, Z. Cong, K. Hang, X. Zou, Chao Zhang, Yan Chen, A. Dai, Anyi Liang, Q. Ming, Mu Wang, Li-Nan Chen, P. Xu, Rulve Chang, Wenbo Feng, T. Xia, Yan Zhang, Beili Wu, Dehua Yang, Lihua Zhao, H. Xu, Ming-Wei Wang

Nature Communications

DOI

2022

Structural genomics of the human dopamine receptor system

P. Xu, Sijie Huang, B. Krumm, Y. Zhuang, C. Mao, Yu-Mu Zhang, Yue Wang, Xi-Ping Huang, Yongfeng Liu, Xin-Heng He, Hua-Dong Li, W. Yin, Yi Jiang, Yan Zhang, B. Roth, H. Xu

bioRxiv

DOI

2022

Molecular mechanism of agonism and inverse agonism in ghrelin receptor

Jiao Qin, Ye Cai, Zheng Xu, Q. Ming, Su-Yu Ji, Chao Wu, Huibing Zhang, C. Mao, D. Shen, K. Hirata, Yan-Bin Ma, Wei Yan, Yan Zhang, Zhenhua Shao

Nature Communications

DOI

2022

Structural basis of peptidomimetic agonism revealed by small-molecule GLP-1R agonists Boc5 and WB4-24

Z. Cong, Qingtong Zhou, Yang Li, Li-Nan Chen, Zichen Zhang, Anyi Liang, Qing Liu, Xiao-yan Wu, A. Dai, T. Xia, Wei Wu, Yan Zhang, Dehua Yang, Ming-Wei Wang

bioRxiv

DOI

2022

Structures of the endogenous peptide- and selective non-peptide agonist-bound SSTR2 signaling complexes

Li-Nan Chen, Wen Wang, Yingjun Dong, D. Shen, Jia Guo, Xuefei Yu, Jiao Qin, Su-Yu Ji, Huibing Zhang, Q. Shen, Qiao-Jun He, Bo Yang, Yan Zhang, Qinglin Li, C. Mao

Cell Research

DOI

2022

GPCRs steer Gi and Gs selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors.

Sijie Huang, P. Xu, D. Shen, Icaro A. Simon, C. Mao, Yangxia Tan, Huibing Zhang, K. Harpsøe, Hua-Dong Li, Yu-Mu Zhang, Chongzhao You, Xue-Kui Yu, Yi Jiang, Yan Zhang, D. Gloriam, H. Xu

Molecules and Cells

DOI

2022

Molecular insights into the distinct signaling duration for the peptide-induced PTH1R activation

Xiuwen Zhai, C. Mao, Qingya Shen, Shaokun Zang, D.-D. Shen, Huibing Zhang, Zhaohong Chen, Gang Wang, Chang-Ming Zhang, Yan Zhang, Zhi-Hong Liu

Nature Communications

DOI

2022

二元醇脂质体对多奈哌齐经皮转运的协同促进作用

王慧，张玲，邵青，张燕，王文杰，杨苗苗，胡婕雯

《中国新药杂志》

2021

Constitutive signal bias mediated by the human GHRHR splice variant 1

Z. Cong, Fu-Lai Zhou, Chao Zhang, X. Zou, Huibing Zhang, Yu-zhe Wang, Qingtong Zhou, Xiao-qing Cai, Qiao-Feng Liu, Jie Li, Lijun Shao, C. Mao, Xi Wang, Ji-Hong Wu, T. Xia, Lihua Zhao, Hua-Liang Jiang, Yan Zhang, H. Eric Xu, Xi Cheng, Dehua Yang, Ming-Wei Wang

Proceedings of the National Academy of Sciences of the United States of America

DOI

2021

Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1

Zhe-Hua Shao, Q. Shen, Bing-Peng Yao, C. Mao, Li-Nan Chen, Huibing Zhang, D. Shen, Chao Zhang, Weijie Li, Xufei Du, Fei Li, Honglei Ma, Zhihua Chen, H. Xu, Song-Min Ying, Yan Zhang, Hua-Hao Shen

Nature Chemical Biology

DOI

2021

Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E2 receptor EP2 subtype

C. Qu, C. Mao, P. Xiao, Q. Shen, Y. Zhong, Fan Yang, D. Shen, X. Tao, Huibing Zhang, Xu Yan, Rui-Jie Zhao, Jun-Yan He, Ying Guan, Chao Zhang, Guihua Hou, Peng-Ju Zhang, Gui-Ge Hou, Zi-Jian Li, Xiao Yu, R. Chai, You-Fei Guan, Jin-Peng Sun, Yan Zhang

Science Advances

DOI

2021

Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor

F. Zhao, Chao Zhang, Qingtong Zhou, K. Hang, X. Zou, Yan Chen, Fan Wu, Q. Rao, A. Dai, W. Yin, D. Shen, Yan Zhang, T. Xia, R. Stevens, H. E. Xu, Dehua Yang, Lihua Zhao, Ming-Wei Wang

bioRxiv

DOI

2021

Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor

Z. Cong, Li-Nan Chen, Honglei Ma, Qingtong Zhou, X. Zou, C. Ye, A. Dai, Qing Liu, Wei Huang, Xian-Qiang Sun, Xi Wang, P. Xu, Lihua Zhao, T. Xia, W. Zhong, Dehua Yang, H. Eric Xu, Yan Zhang, Ming-Wei Wang

Nature Communications

DOI

2021

Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor

Y. Zhuang, B. Krumm, Huibing Zhang, X. E. Zhou, Yue Wang, Xi-Ping Huang, Yongfeng Liu, Xi Cheng, Yi Jiang, Hua-Liang Jiang, Cheng Zhang, W. Yi, B. Roth, Yan Zhang, H. Xu

Cell Research

DOI

2021

Structures of the human dopamine D3 receptor-Gi complexes.

P. Xu, Sijie Huang, C. Mao, B. Krumm, X. E. Zhou, Yangxia Tan, Xi-Ping Huang, Yongfeng Liu, D. Shen, Yi Jiang, Xue-Kui Yu, Hua-Liang Jiang, K. Melcher, B. Roth, Xi Cheng, Yan Zhang, H. Xu

Molecules and Cells

DOI

2021

Structural basis for the therapeutic advantage of dual and triple agonists at the human GIP, GLP-1 or GCG receptors

F. Zhao, Qingtong Zhou, Z. Cong, K. Hang, X. Zou, Chao Zhang, Yan Chen, A. Dai, Anyi Liang, Q. Ming, Mu Wang, Li-Nan Chen, P. Xu, Rulue Chang, Wenbo Feng, T. Xia, Yan Zhang, Beili Wu, Dehua Yang, Lihua Zhao, H. Xu, Ming-Wei Wang

bioRxiv

DOI

2021

Structures of full-length glycoprotein hormone receptor signalling complexes

J. Duan, P. Xu, Xi Cheng, C. Mao, T. Croll, Xin-Heng He, Jingjing Shi, X. Luan, W. Yin, E. You, Qiufeng Liu, Shu-Yang Zhang, Hua-Liang Jiang, Yan Zhang, Yi Jiang, H. Xu

Nature

DOI

2021

Structural insights into ligand recognition and activation of the melanocortin-4 receptor

Huibing Zhang, Li-Nan Chen, Dehua Yang, C. Mao, Q. Shen, Wenbo Feng, D. Shen, A. Dai, Shan-Shan Xie, Yan Zhou, Jiao Qin, Jin-Peng Sun, Daniel H. Scharf, Tingjun Hou, Tian-Hua Zhou, Ming-Wei Wang, Yan Zhang

Cell Research

DOI

2021

Structural insights into the lipid and ligand regulation of serotonin receptors

P. Xu, Sijie Huang, Huibing Zhang, C. Mao, X. E. Zhou, Xi Cheng, Icaro A. Simon, D. Shen, Hsin-Yung Yen, C. Robinson, K. Harpsøe, B. Svensson, Jia Guo, Hua-Liang Jiang, D. Gloriam, K. Melcher, Yi Jiang, Yan Zhang, H. Xu

Nature

DOI

2021

Structural basis of GABAB receptor–Gi protein coupling

Cangsong Shen, C. Mao, Chanjuan Xu, Nan Jin, Huibing Zhang, D. Shen, Q. Shen, Xiaomei Wang, T. Hou, Zhong Chen, P. Rondard, J. Pin, Yan Zhang, Jianfeng Liu

Nature

DOI

2021

Structural insights into the human D1 and D2 dopamine receptor signaling complexes

Y. Zhuang, P. Xu, C. Mao, Lei Wang, B. Krumm, X. E. Zhou, Sijie Huang, Heng Liu, Xi Cheng, Xi-Ping Huang, D. Shen, Ting-Hai Xu, Yongfeng Liu, Yue Wang, Jia Guo, Yi Jiang, Hua-Liang Jiang, K. Melcher, B. Roth, Yan Zhang, Cheng Zhang, H. Xu

Cell

DOI

2021

Structures of the glucocorticoid-bound adhesion receptor GPR97–Go complex

Y. Ping, C. Mao, P. Xiao, Rui-Jie Zhao, Yi Jiang, Zhao-Ya Yang, W. An, D. Shen, Fan Yang, Huibing Zhang, C. Qu, Q. Shen, Cai-Ping Tian, Zi-Jian Li, Shaolong Li, Guangpu Wang, X. Tao, Xin Wen, Y. Zhong, Jing Yang, F. Yi, Xiao Yu, H. E. Xu, Yan Zhang, Jin-Peng Sun

Nature

DOI

2021

8-[(3,4,4-三氟丁-3-烯-1-基)硫基]取代的新型甲基黄嘌呤及其衍生物的合成和生物活性

刘航，张舒昀，李欢，张燕，李正名，王宝雷

《有机化学》

2020

Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors.

Shanshan Ma, Q. Shen, Lihua Zhao, C. Mao, X. E. Zhou, D. Shen, P. de Waal, P. Bi, Chuntao Li, Yi Jiang, Ming-wei Wang, P. M. Sexton, D. Wootten, K. Melcher, Yan Zhang, H. E. Xu

Molecules and Cells

DOI

2020

Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 2 receptor in complex with Gs protein and Nb35

S. Ma, Q. Shen, Lihua Zhao, C. Mao, X.-E. Zhou, D. Shen, P. de Waal, P. Bi, Chuankui Li, Yi Jiang, Ming-wei Wang, P. Sexton, D. Wootten, K. Melcher, Yan Zhang, Hai-Lun Xu

DOI

2020

Structural basis of GPBAR activation and bile acid recognition

Fan Yang, C. Mao, Lu Guo, Jingyu Lin, Q. Ming, P. Xiao, Xiang Wu, Q. Shen, Shimeng Guo, D. Shen, Ruirui Lu, Lin-Qi Zhang, Shenming Huang, Y. Ping, Chen-Lu Zhang, Cheng Ma, Kai Zhang, Xiaoying Liang, Yue-Mao Shen, F. Nan, Fan Yi, V. Luca, Jiu-Yao Zhou, Chang-Tao Jiang, Jin-Peng Sun, Xin Xie, Xiaohui Yu, Yan Zhang

Nature

DOI

2020

Cell active and functionally-relevant small-molecule agonists of calcitonin receptor.

Shuai Zhao, Sheng-Chao Guo, C. Yang, Zheng Gong, Yaomin Wang, Ying-Li Jia, Xinyu Jiang, Li-Wei Xu, Li Shi, Xiao Yu, Jin-Peng Sun, Yan Zhang, Xin Chen

Bioorganic chemistry (Print)

DOI

2020

Cryo-EM structures of inactive and active GABAB receptor

C. Mao, Cangsong Shen, Chuntao Li, D. Shen, Chanjuan Xu, Sheng-Lan Zhang, R. Zhou, Q. Shen, Li-Nan Chen, Zhi-Nong Jiang, Jianfeng Liu, Yan Zhang

Cell Research

DOI

2020

Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy

J. Duan, D. Shen, X. E. Zhou, P. Bi, Qiufeng Liu, Yangxia Tan, Y. Zhuang, Huibing Zhang, P. Xu, Sijie Huang, Shan-Shan Ma, Xin-Heng He, K. Melcher, Yan Zhang, H. E. Xu, Yi Jiang

Nature Communications

DOI

2020

Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 1 receptor in complex with Gs protein and Nb35

S. Ma, Q. Shen, Lihua Zhao, C. Mao, X.-E. Zhou, D. Shen, P. de Waal, P. Bi, Chuankui Li, Y. Jiang, Mei-Tian Wang, P. Sexton, D. Wootten, K. Melcher, Yan Zhang, H.-E. Xu

DOI

2020

Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation.

Yi-Lynn Liang, M. Belousoff, Pei-Shen Zhao, C. Koole, Madeleine M. Fletcher, Tin T. Truong, Villy Julita, G. Christopoulos, H. E. Xu, Yan Zhang, M. Khoshouei, A. Christopoulos, R. Danev, P. M. Sexton, Denise Wootten

Molecules and Cells

DOI

2020

Structural basis for activation of the growth hormone-releasing hormone receptor

Fu-Lai Zhou, Huibing Zhang, Z. Cong, Lihua Zhao, Qingtong Zhou, C. Mao, Xi Cheng, D. Shen, Xiao-qing Cai, Cheng Ma, Yu-zhe Wang, A. Dai, Yan Zhou, Wen Sun, F. Zhao, Suwen Zhao, Hua-Liang Jiang, Yi Jiang, Dehua Yang, H. Eric Xu, Yan Zhang, Ming-Wei Wang

Nature Communications

DOI

2020

A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor

Wen Sun, Li-Nan Chen, Qingtong Zhou, Lihua Zhao, Dehua Yang, Huibing Zhang, Z. Cong, D. Shen, F. Zhao, Fu-Lai Zhou, Xiao-qing Cai, Yan Chen, Yan Zhou, S. Gadgaard, W. V. D. van der Velden, Suwen Zhao, Yi Jiang, M. Rosenkilde, H. E. Xu, Yan Zhang, Ming-Wei Wang

Cell Research

DOI

2020

Cryo-EM structures of inactive and Gi-coupled GABAB heterodimer

C. Mao, Cangsong Shen, Chuntao Li, D. Shen, Chanjuan Xu, Sheng-Lan Zhang, R. Zhou, Q. Shen, Li-Nan Chen, Zhi-Nong Jiang, Jianfeng Liu, Yan Zhang

bioRxiv

DOI

2020

Structural basis of bile acid receptor activation and Gs coupling

Fan Yang, C. Mao, Lulu Guo, Jingyu Lin, Q. Ming, P. Xiao, Xiang Wu, Q. Shen, Shimeng Guo, D. Shen, R. Lu, Lin-Qi Zhang, Shenming Huang, Y. Ping, Chen-Lu Zhang, Cheng Ma, Kai Zhang, Xiaoying Liang, Yue-Mao Shen, F. Nan, F. Yi, V. Luca, Jiu-Yao Zhou, Chang-Tao Jiang, Jin-Peng Sun, Xin Xie, Xiao Yu, Yan Zhang

bioRxiv

DOI

2020

Dopaminergic Pharmacology Revealed by Structures of Human Dopamine D3 Receptor-G i Complexes

P. Xu, Sijie Huang, C. Mao, X. E. Zhou, Yangxia Tan, Chen-Jun Jia, D. Shen, Yi Jiang, Xue-Kui Yu, Hua-Liang Jiang, K. Melcher, Xi Cheng, Yan Zhang, H. Xu

Social Science Research Network

DOI

2020

樟脑基缩氨基硫脲衍生物通过活性氧(ROS)介导的线粒体途径诱导人乳腺癌细胞的G2期阻滞和凋亡（英文）

张燕，王芸芸，赵雨珣，张成龙，谷文，王忠龙，朱永强，王石发

《有机化学》

2020

硝苯地平缓释片Ⅱ仿制药体外溶出一致性评价研究

周星彤，张燕，杨钊

《中国临床药理学杂志》

DOI

2020

奥美拉唑肠溶胶囊高脂餐后健康人体生物等效性试验

孙成，周玲玲，张燕，黄术林，姜彬

《中国临床药理学杂志》

2019

A complex structure of arrestin-2 bound to neurotensin receptor 1

W. Yin, Zong-Dong Li, M. Jin, Yan-Qing Yin, P. de Waal, K. Pal, Xiang Gao, Yuanzheng He, Jing Gao, Xue-Jian Wang, Yan Zhang, Hui Zhou, K. Melcher, Yuhui Jiang, Y. Cong, X.-E. Zhou, Xin Yu, H.-E. Xu

DOI

2019

OR30-3 Structural Basis of Activation and Sustained Signaling by the PTH Receptor

Ieva Sutkeviciute, Lihua Zhao, Yan Zhang, H. Xu, Jean-Pierre Vilardaga

Journal of the Endocrine Society

DOI

2019

[Single-particle cryo-electron microscopy opens new avenues in structural biology of G protein-coupled receptor].

Chuntao Li, Huibing Zhang, Yan Zhang

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences

DOI

2019

Structure and dynamics of the active human parathyroid hormone receptor-1

Lihua Zhao, Shanshan Ma, Ieva Sutkeviciute, D. Shen, X. E. Zhou, P. de Waal, Chen-Yao Li, Yan-Yong Kang, L. Clark, F. Jean-Alphonse, A. White, Dehua Yang, A. Dai, Xiao-qing Cai, Jian Chen, Cong Li, Yi Jiang, Tomoyuki Watanabe, T. Gardella, K. Melcher, Ming-wei Wang, Jean-Pierre Vilardaga, H. E. Xu, Yan Zhang

Science

DOI

2019

Structural Basis of Activation and Sustained Signaling by the PTH Receptor

Ieva Sutkeviciute, Lihua Zhao, Yan Zhang, E. Xu, Jean-Pierre Vilardaga

The FASEB Journal

DOI

2019

A complex structure of arrestin-2 bound to a G protein-coupled receptor

W. Yin, Zhihai Li, M. Jin, Yu-Ling Yin, P. de Waal, K. Pal, Yan-Ting Yin, Xiang Gao, Yuanzheng He, Jing Gao, Xiaoxi Wang, Yan Zhang, Hu Zhou, K. Melcher, Yi Jiang, Y. Cong, X. E. Zhou, Xue-Kui Yu, H. E. Xu

Cell Research

DOI

2019

3-(((3-溴-1-(3-氯吡啶-2-基)-1H-吡唑-5-基)亚甲基)氨基)取代苯并[d][1,2,3]三嗪-4(3H)-酮类化合物的合成及生物活性

张燕，朱洪伟，尚俊峰，王宝雷，李正名

《有机化学》

2019

不同厂家羟丙甲纤维素理化性质表征及其对缓释效果的影响

朱玉苹，杨钊，张燕，周星彤，张帅华

《中国药学杂志》

2018

卡马西平与氢氯噻嗪共晶的表征与性质的研究

朱玉苹，张燕，杨钊，张帅华，刘坤

《药物分析杂志》

2018

一种基于异长叶烷酮的新型pH荧光探针及其生物荧光成像应用

张燕，王忠龙，陶钰，徐徐，方华，王石发

《有机化学》

2017

具有氧化稳定性的间苯三酚薄膜衣片的处方、制备工艺及质量标准研究

陈丹，刘宏，姚晨，金晓东，张燕，秦烨，郝菲，陈旭，杨瑞玲

《中国新药杂志》

2016

新型含取代哌嗪的5-(吡啶-3-基)-1,2,4-三唑Mannich碱和双Mannich碱的合成及生物活性

张燕，王宝雷，詹益周，张丽媛，李永红，李正名

《高等学校化学学报》

2016

阿达帕林的多晶型筛选和制备与表征研究

张燕，龚宁波，吕扬

《中国新药杂志》

2014

顶空气相色谱法测定头孢替坦二钠中的残留溶剂

杨钊，张燕，谢宜名，徐红，刘亚萍

《中国药学杂志》

2013

苯丁酸氮芥的七、八元瓜环包合物的稳定性研究

张冬兵，李代禧，张燕，翟振，刘立

《计算机与应用化学》

2013

苯丁酸氮芥的α-环糊精包合物的包合稳定性研究

张冬兵，李代禧，张燕，翟振

《计算机与应用化学》

2012

真空条件下肌酐的葫芦脲包合物的稳定性研究

张燕，李代禧，翟振，刘宝林，张冬兵，刘立，余华星

《计算机与应用化学》

2007

二阶导数光谱法测定硫酸阿托品胶浆剂的含量

王彦，张燕

《药物分析杂志》

2003

HPLC法测定盐酸萘甲唑啉的含量

谭会洁，刘斐，张燕

《药学研究》

2003

紫外分光光度法测定头孢拉定颗粒剂的含量

李之琳，王珏，张伟，张燕

《中国抗生素杂志》

1989

双波长吸收光谱系数倍率法测定硝苯啶及其制剂的含量

于盛茂，张燕

《中国医药工业杂志》

1988

酸性染料比色法测定颠茄酊的含量

赖新平，张燕

《药学研究》

1988

先锋必素含量测定方法的探讨

李正翔，王少敏，张燕

《中国药学杂志》

1985

山莨菪碱选择性电极的研究

沈国励，张燕，俞汝勤

《药学学报》

会议论文

2018

N-Heterocyclic Carbene Catalyzed [3+4] Annulation of Enals and Azadienes:Enantioselective Synthesis of Bioactive Benzofuroazepinones

Zhong-Hua Gao, Kun-Quan Chen, Yan Zhang, Ling-Mei Kong, Yan Li, Song Ye

《中国化学会第十二届全国天然有机化学学术会议论文摘要集》

DOI

2018

Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as potent and selective CBP bromodomain inhibitors

Qiuping Xiang, Yan Zhang, Chao Wang, Cheng Zhang, Rui Wang, Lingjiao Zou, Yong Xu

《第11届世界华人药物化学研讨会（ISCMC 2018）论文摘要集》

2017

Photoinduced N-methylation and N-sulfonylation of azobenzenes with DMSO under mild reaction conditions

Ning Xu, Yan Zhang, Wei Chen, Pinhua Li, Lei Wang

《中国化学会第十四届全国有机合成化学学术研讨会》

2015

Synthesis of Allenylphosphonates and Triaryl-substituted Allenes through CuI-Catalyzed Coupling of Terminal Alkynes with Diazophosphonates and Diaryldiazonmethanes

Chenggui Wu, Fei Ye, Guisheng Deng, Yan Zhang, Jianbo wang

《中国化学会第九届全国有机化学学术会议论文摘要集（3）》

预印本

2025

Generating $π$-Functional Molecules Using STGG+ with Active Learning

Alexia Jolicoeur-Martineau, Yan Zhang, Boris Knyazev, Aristide Baratin, Cheng-Hao Liu

arXiv preprint

2024

Influencing Factors of the FLASH Effect: Unveiling the Importance of Free Radicals

Yan Zhang, Chenyang Huang, Ankang Hu, Yucheng Wang, Wanyi Zhou, Jiaqi Qiu, Jian Wang, Qibin Fu, Tuchen Huang, Hao Zha, Wei Wang, Xiaowu Deng, Junli Li

arXiv preprint

2024

Adapter-dependent Adapter Methylation Assay

Jia Zhang, Peng Qi, Li Xiao, Mengxi Yuan, Jun Chuan, Yaling Zeng, Li-mei Lin, Yue Gu, Yan Zhang, Duan-fang Liao, Kai Li

arXiv preprint

2023

Evolutionary Retrosynthetic Route Planning

Yan Zhang, Hao Hao, Xiao He, Shuanhu Gao, Aimin Zhou

arXiv preprint

DOI

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