梁爽｜吉林大学｜学者主页

2026

The regulatory role of INSIG1 in testicular Sertoli cells in boars

Shaoxuan Zhang, Hang Zhou, Simin Liu, Li J, Dali Wang, Boxing Sun, Hao Sun, Shuang Liang

Theriogenology

DOI

2026

Oxidative-stress-mediated apoptosis triggered by microplastics disrupts bovine oocyte maturation

Yu Wang, Jiaming Yue, Yijing Yin, Yan Zhang, Yi Zheng, Hao Jiang, Jiabao Zhang, Bao Yuan, Shuang Liang

Theriogenology

DOI

2026

Epigenetic reprogramming in SCNT embryos: from inefficient remodeling to precision enhancement

Yanan Zhao, Yu Wang, Yanqiu Wang, Sihang Yu, Hongxu Yang, Mingming Miao, Hang Zhou, Hao Sun, Boxing Sun, Luyao Bie, Shuang Liang

Epigenetics & Chromatin

DOI

2026

Single-blastomere transcriptomics identifies NR5A2-associated metabolic genes during porcine zygotic genome activation

Zihan Li, Fuheng Xie, Yuqing He, Ma Li, Shuang Liang, Qiang Liu

Theriogenology

DOI

2026

Transcriptome and metabolome analysis reveals that cuproptosis in bovine cumulus cells triggers the intercellular transmission of senescence and mitochondrial dysfunction to impair oocyte quality

H G Xu, Tian Tian, Dan Xu, Xiaoxue Du, Rui Su, Jinghong Liang, Ying Liu, Yuqing Zhang, Chang Liu, Shuang Liang, LI Qingying, Deli Ding, Yongsheng Han, Bo Zhai, Jidong Li, Chengzhen Chen, Jiabao Zhang, Hao Jiang, Bao Yuan

Theriogenology

DOI

2026

Multiomics analysis reveals that chlorogenic acid alleviates heat stress-induced oxidative damage in prepubertal boar testes via the BLVRA-GPX3 pathway: in vivo and in vitro evidence

Shaoxuan Zhang, Dali Wang, Jiajia Qi, Jing Li, Simin Liu, Hao Sun, Shuang Liang, Boxing Sun

Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology

DOI

2025

GAS1 affects proliferation, apoptosis, and steroid hormone levels by regulating mitochondrial functions and the PI3K/AKT pathway in bovine granulosa cells

Wenjie Yu, Na Pei, Haitao Jia, Yijing Yin, Hong Xu, Tian Tian, Chang Liu, Lingxia Xu, Ze Li, Zibin Liu, Xiaoshi Cai, Mingkai Yu, Shuang Liang, Chengzhen Chen, Jiabao Zhang, Bao Yuan, Hao Jiang

Theriogenology

DOI

2025

Corrigendum to “FOXM1 affects oxidative stress, mitochondrial function, and the DNA damage response by regulating p21 in aging oocytes” [Theriogenology 229 (2024) 66–74]

Wenjie Yu, Xiaoshi Cai, Chen Wang, Xinyue Peng, Lingxia Xu, Yan Gao, Tian Tian, Guangying Zhu, Yuan Pan, Hongzhong Chu, Shuang Liang, Chengzhen Chen, Nam-Hyung Kim, Bao Yuan, Jiabao Zhang, Hao Jiang

Theriogenology

DOI

2025

Fisetin alleviates oxidative stress and promotes porcine early embryonic development via activation of the NRF2-ARE signalling pathway

Hua‐Kai Wei, Jiajia Qi, Yan-Qiu Wang, Hexuan Qu, Chen-Xuan Yan, Tian-Tian Li, Yu Wang, Hao Sun, Boxing Sun, Shuang Liang

Animal Bioscience

DOI

2024

FOXM1 affects oxidative stress, mitochondrial function, and the DNA damage response by regulating p21 in aging oocytes

Wenjie Yu, Xiaoshi Cai, Chen Wang, Xinyue Peng, Lingxia Xu, Yan Gao, Tian Tian, Guangying Zhu, Yuan Pan, Hongzhong Chu, Shuang Liang, Chengzhen Chen, Nam‐Hyung Kim, Bao Yuan, Jiabao Zhang, Hao Jiang

Theriogenology

DOI

2024

Thyroxine regulates pig Sertoli cell line proliferation and maturation through the IKK/NFκB and p38 MAPK signaling pathways

Jing Li, Shao-Xuan Zhang, Da-Li Wang, Jiajia Qi, Chunyan Bai, Hao Sun, Hao Sun, Bo-Xing Sun, Shuang Liang

Theriogenology

DOI

2024

Transcriptome analysis of porcine oocytes during postovulatory aging

Wenjie Yu, Xinyue Peng, Xiaoshi Cai, Hong Xu, Chen Wang, Fengjiao Liu, Dan Luo, Shuhan Tang, Yue Wang, Xiaoxue Du, Yan Gao, Tian Tian, Shuang Liang, Chengzhen Chen, Nam‐Hyung Kim, Bao Yuan, Jiabao Zhang, Hao Jiang

Theriogenology

DOI

2024

Lysine-specific demethylase 1 (LSD1) participate in porcine early embryonic development by regulating cell autophagy and apoptosis through the mTOR signaling pathway

Jiajia Qi, Shaoxuan Zhang, Hexuan Qu, Yanqiu Wang, Yanwei Dong, Hua‐Kai Wei, Yu Wang, Boxing Sun, Hao Jiang, Jiabao Zhang, Shuang Liang

Theriogenology

DOI

2024

Oleanolic acid improves the in vitro developmental competence of early porcine embryos by reducing oxidative stress and ameliorating mitochondrial function

Yan‐Wei Dong, He‐Xuan Qu, Yan-Qiu Wang, Jiajia Qi, Hua‐Kai Wei, Boxing Sun, Hao Sun, Shuang Liang

Animal Bioscience

DOI

2024

Chlorogenic acid improves the development of porcine parthenogenetic embryos by regulating oxidative stress and ameliorating mitochondrial function

He‐Xuan Qu, Yan‐Qiu Wang, Yan‐Wei Dong, Jiajia Qi, Hua‐Kai Wei, Yan Zhang, Hao Sun, Boxing Sun, Shuang Liang

Reproduction in Domestic Animals

DOI

2023

Inhibition of FSP1 impairs early embryo developmental competence in pigs

Yan-Qiu Wang, He‐Xuan Qu, Yan‐Wei Dong, Jiajia Qi, Hua‐Kai Wei, Hao Sun, Hao Sun, Hao Jiang, Jiabao Zhang, Boxing Sun, Shuang Liang

Theriogenology

DOI

2023

Chlorogenic acid ameliorates the heat stress-induced impairment of porcine Sertoli cells by suppressing oxidative stress and apoptosis

Shao-Xuan Zhang, Dali Wang, Jiajia Qi, Yuwei Yang, Hao Sun, Hao Sun, Bo-Xing Sun, Shuang Liang

Theriogenology

DOI

2023

Ferulic acid ameliorates the quality of in vitro-aged bovine oocytes by suppressing oxidative stress and apoptosis

Yijing Yin, Yonghong Zhang, Yu Wang, Hao Jiang, Jiabao Zhang, Shuang Liang, Bao Yuan

Aging

DOI

2023

Ferulic Acid Enhances Oocyte Maturation and the Subsequent Development of Bovine Oocytes

Yu Wang, Jiajia Qi, Yijing Yin, Hao Jiang, Jiabao Zhang, Shuang Liang, Bao Yuan

International Journal of Molecular Sciences

DOI

2023

6-Gingerol Improves In Vitro Porcine Embryo Development by Reducing Oxidative Stress

Wenjie Yu, Yanxia Peng, Xinyue Peng, Ze Li, Chang Liu, Liu Yang, Yan Gao, Shuang Liang, Bao Yuan, Chengzhen Chen, Nam‐Hyung Kim, Hao Jiang, Jiabao Zhang

Animals

DOI

2023

Maslinic Acid Supplementation during the In Vitro Culture Period Ameliorates Early Embryonic Development of Porcine Embryos by Regulating Oxidative Stress

Ting-Ting Yang, Jiajia Qi, Boxing Sun, He‐Xuan Qu, Hua‐Kai Wei, Hao Sun, Hao Jiang, Jiabao Zhang, Shuang Liang

Animals

DOI

2021

Schisanhenol improves early porcine embryo development by regulating the phosphorylation level of MAPK

Wen-Jie Yu, Chengzhen Chen, Yanxia Peng, Ze Li, Yan Gao, Shuang Liang, Bao Yuan, Nam‐Hyung Kim, Hao Jiang, Jiabao Zhang

Theriogenology

DOI

2021

Tributyltin Oxide Exposure During in vitro Maturation Disrupts Oocyte Maturation and Subsequent Embryonic Developmental Competence in Pigs

Yue Xiao, Bao Yuan, Weiyi Hu, Jiajia Qi, Hao Jiang, Boxing Sun, Jiabao Zhang, Shuang Liang

Frontiers in Cell and Developmental Biology

DOI

2021

Supplementation with asiatic acid during in vitro maturation improves porcine oocyte developmental competence by regulating oxidative stress

Jiajia Qi, Xiaoxia Li, Yan Zhang, Yunfei Diao, Weiyi Hu, Dali Wang, Hao Jiang, Jiabao Zhang, Boxing Sun, Shuang Liang

Theriogenology

DOI

2021

Iron Overload-Induced Ferroptosis Impairs Porcine Oocyte Maturation and Subsequent Embryonic Developmental Competence in vitro

Weiyi Hu, Yan Zhang, Dali Wang, Tingting Yang, Jiajia Qi, Yonghong Zhang, Hao Jiang, Jiabao Zhang, Boxing Sun, Shuang Liang

Frontiers in Cell and Developmental Biology

DOI

2021

Melatonin ameliorates cypermethrin-induced impairments by regulating oxidative stress, DNA damage and apoptosis in porcine Sertoli cells

Jing Li, Boxing Sun, Dali Wang, Ying Liu, Jiajia Qi, Xiao-Wei Nie, Chunyan Bai, Jiabao Zhang, Shuang Liang

Theriogenology

DOI

2021

Glycine ameliorates mitochondrial dysfunction caused by ABT-199 in porcine oocytes

Sicong Yu, Lepeng Gao, Yang Song, Xin Ma, Shuang Liang, Hainan Lan, Xin Zheng, Suo Li

Journal of Animal Science

DOI

2021

Chlorogenic Acid Ameliorates Damage Induced by Fluorene-9-Bisphenol in Porcine Sertoli Cells

Shaoxuan Zhang, Boxing Sun, Dali Wang, Ying Liu, Jing Li, Jiajia Qi, Yonghong Zhang, Chunyan Bai, Shuang Liang

Frontiers in Pharmacology

DOI

2021

Glycine alleviates fluoride‐induced oxidative stress, apoptosis and senescence in a porcine testicular Sertoli cell line

Ying Liu, Boxing Sun, Shaoxuan Zhang, Jing Li, Jiajia Qi, Chunyan Bai, Jiabao Zhang, Shuang Liang

Reproduction in Domestic Animals

DOI

2020

Asiatic acid protects oocytes against in vitro aging-induced deterioration and improves subsequent embryonic development in pigs

Weiyi Hu, Xiao Xia Li, Yun Fei Diao, Jiajia Qi, Dali Wang, Jiabao Zhang, Boxing Sun, Shuang Liang

Aging

DOI

2020

Carnosic acid improves porcine early embryonic development by inhibiting the accumulation of reactive oxygen species

Yanxia Peng, Chengzhen Chen, Dan Luo, Wenjie Yu, Sheng‐Peng Li, Yue Xiao, Bao Yuan, Shuang Liang, Xuerui Yao, Nam‐Hyung Kim, Hao Jiang, Jiabao Zhang

Journal of Reproduction and Development

DOI

2019

Asiatic acid supplementation during the in vitro culture period improves early embryonic development of porcine embryos produced by parthenogenetic activation, somatic cell nuclear transfer and in vitro fertilization

Jiajia Qi, Xiao Xia Li, Yun Fei Diao, Peng-Lei Liu, Dali Wang, Chunyan Bai, Bao Yuan, Shuang Liang, Boxing Sun

Theriogenology

DOI

2019

Rosmarinic acid treatment during porcine oocyte maturation attenuates oxidative stress and improves subsequent embryo developmentin vitro

Yan Zhang, Jing Guo, Xiao Wei Nie, Zi Yue Li, Yumeng Wang, Shuang Liang, Suo Li

PeerJ

DOI

2018

Inhibition of cathepsin B activity prevents deterioration in the quality of in vitro aged porcine oocytes

Shuang Liang, Hao Jiang, Xing‐Hui Shen, Jiabao Zhang, Nam‐Hyung Kim

Theriogenology

DOI

2018

Laminarin improves developmental competence of porcine early stage embryos by inhibiting oxidative stress

Hao Jiang, Shuang Liang, Xuerui Yao, Yong-Xun Jin, Xing‐Hui Shen, Bao Yuan, Jiabao Zhang, Nam‐Hyung Kim

Theriogenology

DOI

2018

Autophagy is required for proper meiosis of porcine oocytes maturing in vitro

Xing‐Hui Shen, Yong-Xun Jin, Shuang Liang, Jeongwoo Kwon, Ji-Wei Zhu, Lei Lei, Nam‐Hyung Kim

Scientific Reports

DOI

2018

Overexpression of MicroRNA-29b Decreases Expression of DNA Methyltransferases and Improves Quality of the Blastocysts Derived from Somatic Cell Nuclear Transfer in Cattle

Shuang Liang, Zheng‐Wen Nie, Jing Guo, Yingjie Niu, Kyung‐Tae Shin, Sun A Ock, Xiang‐Shun Cui

Microscopy and Microanalysis

DOI

2018

Laminarin enhances the quality of aged pig oocytes by reducing oxidative stress

Xuerui Yao, Hao Jiang, Shuang Liang, Xing‐Hui Shen, Qingshan Gao, Yong Nan XU, Nam‐Hyung Kim

Journal of Reproduction and Development

DOI

2017

Toxic effects of atrazine on porcine oocytes and possible mechanisms of action

Bao Yuan, Shuang Liang, Yong-Xun Jin, Mingjun Zhang, Jiabao Zhang, Nam‐Hyung Kim

PLoS ONE

DOI

2017

C-Phycocyanin supplementation during in vitro maturation enhances pre-implantation developmental competence of parthenogenetic and cloned embryos in pigs

Shuang Liang, Jing Guo, Yong Xun Jin, Bao Yuan, Jiabao Zhang, Nam‐Hyung Kim

Theriogenology

DOI

2017

Sodium fluoride exposure exerts toxic effects on porcine oocyte maturation

Shuang Liang, Zheng‐Wen Nie, Minghui Zhao, Yingjie Niu, Kyung‐Tae Shin, Xiang‐Shun Cui

Scientific Reports

DOI

2017

Melatonin enhances the developmental competence of porcine somatic cell nuclear transfer embryos by preventing DNA damage induced by oxidative stress

Shuang Liang, Yong-Xun Jin, Bao Yuan, Jiabao Zhang, Nam‐Hyung Kim

Scientific Reports

DOI

2006

UT-B基因敲除雌性小鼠生殖延迟原因与机制的研究

梁爽

《吉林大学》

精选作品

期刊论文

The regulatory role of INSIG1 in testicular Sertoli cells in boars

Oxidative-stress-mediated apoptosis triggered by microplastics disrupts bovine oocyte maturation

Epigenetic reprogramming in SCNT embryos: from inefficient remodeling to precision enhancement

Single-blastomere transcriptomics identifies NR5A2-associated metabolic genes during porcine zygotic genome activation

Transcriptome and metabolome analysis reveals that cuproptosis in bovine cumulus cells triggers the intercellular transmission of senescence and mitochondrial dysfunction to impair oocyte quality

Multiomics analysis reveals that chlorogenic acid alleviates heat stress-induced oxidative damage in prepubertal boar testes via the BLVRA-GPX3 pathway: in vivo and in vitro evidence

GAS1 affects proliferation, apoptosis, and steroid hormone levels by regulating mitochondrial functions and the PI3K/AKT pathway in bovine granulosa cells

Corrigendum to “FOXM1 affects oxidative stress, mitochondrial function, and the DNA damage response by regulating p21 in aging oocytes” [Theriogenology 229 (2024) 66–74]

Fisetin alleviates oxidative stress and promotes porcine early embryonic development via activation of the NRF2-ARE signalling pathway

FOXM1 affects oxidative stress, mitochondrial function, and the DNA damage response by regulating p21 in aging oocytes

Thyroxine regulates pig Sertoli cell line proliferation and maturation through the IKK/NFκB and p38 MAPK signaling pathways

Transcriptome analysis of porcine oocytes during postovulatory aging

Lysine-specific demethylase 1 (LSD1) participate in porcine early embryonic development by regulating cell autophagy and apoptosis through the mTOR signaling pathway

Oleanolic acid improves the in vitro developmental competence of early porcine embryos by reducing oxidative stress and ameliorating mitochondrial function

Chlorogenic acid improves the development of porcine parthenogenetic embryos by regulating oxidative stress and ameliorating mitochondrial function

Inhibition of FSP1 impairs early embryo developmental competence in pigs

Chlorogenic acid ameliorates the heat stress-induced impairment of porcine Sertoli cells by suppressing oxidative stress and apoptosis

Ferulic acid ameliorates the quality of in vitro-aged bovine oocytes by suppressing oxidative stress and apoptosis

Ferulic Acid Enhances Oocyte Maturation and the Subsequent Development of Bovine Oocytes

6-Gingerol Improves In Vitro Porcine Embryo Development by Reducing Oxidative Stress

Maslinic Acid Supplementation during the In Vitro Culture Period Ameliorates Early Embryonic Development of Porcine Embryos by Regulating Oxidative Stress

Schisanhenol improves early porcine embryo development by regulating the phosphorylation level of MAPK

Tributyltin Oxide Exposure During in vitro Maturation Disrupts Oocyte Maturation and Subsequent Embryonic Developmental Competence in Pigs

Supplementation with asiatic acid during in vitro maturation improves porcine oocyte developmental competence by regulating oxidative stress

Iron Overload-Induced Ferroptosis Impairs Porcine Oocyte Maturation and Subsequent Embryonic Developmental Competence in vitro

Melatonin ameliorates cypermethrin-induced impairments by regulating oxidative stress, DNA damage and apoptosis in porcine Sertoli cells

Glycine ameliorates mitochondrial dysfunction caused by ABT-199 in porcine oocytes

Chlorogenic Acid Ameliorates Damage Induced by Fluorene-9-Bisphenol in Porcine Sertoli Cells

Glycine alleviates fluoride‐induced oxidative stress, apoptosis and senescence in a porcine testicular Sertoli cell line

Asiatic acid protects oocytes against in vitro aging-induced deterioration and improves subsequent embryonic development in pigs

Carnosic acid improves porcine early embryonic development by inhibiting the accumulation of reactive oxygen species

Asiatic acid supplementation during the in vitro culture period improves early embryonic development of porcine embryos produced by parthenogenetic activation, somatic cell nuclear transfer and in vitro fertilization

Rosmarinic acid treatment during porcine oocyte maturation attenuates oxidative stress and improves subsequent embryo developmentin vitro

Inhibition of cathepsin B activity prevents deterioration in the quality of in vitro aged porcine oocytes

Laminarin improves developmental competence of porcine early stage embryos by inhibiting oxidative stress

Autophagy is required for proper meiosis of porcine oocytes maturing in vitro

Overexpression of MicroRNA-29b Decreases Expression of DNA Methyltransferases and Improves Quality of the Blastocysts Derived from Somatic Cell Nuclear Transfer in Cattle

Laminarin enhances the quality of aged pig oocytes by reducing oxidative stress

Toxic effects of atrazine on porcine oocytes and possible mechanisms of action

C-Phycocyanin supplementation during in vitro maturation enhances pre-implantation developmental competence of parthenogenetic and cloned embryos in pigs

Sodium fluoride exposure exerts toxic effects on porcine oocyte maturation

Melatonin enhances the developmental competence of porcine somatic cell nuclear transfer embryos by preventing DNA damage induced by oxidative stress

UT-B基因敲除雌性小鼠生殖延迟原因与机制的研究

会议论文

体细胞核移植技术生产转单体红色荧光蛋白五指山小型猪

利用体细胞核移植技术生产表达红色荧光蛋白的猪转基因克隆胚胎

研究方向