张欣欣｜哈尔滨医科大学｜学者主页

2026

ZBED2调控JAK信号对卵巢癌细胞增殖、侵袭与迁移的影响

张欣欣，董艳，李君，霍延琴

《中国妇产科临床杂志》

DOI

2026

CancerSEA-X: A Single-cell Resource for Tumor Microenvironment Cell States Across over 30 Cancer Types.

Lantian Deng, Wei Liu, Jinyuan Xu, Bo Zhang, Shengyuan He, Kun Liu, Xinxin Zhang, Huating Yuan, Fei Quan, Yun Xiao

Genomics, Proteomics & Bioinformatics

DOI

2025

Single-cell transcriptomes reveal cell-type-specific and sample-specific gene function in human cancer

Huating Yuan, Xin Liang, Xinxin Zhang, Yu Cao

Heliyon

DOI

2023

Computational Quantification of Cancer Immunoediting.

Kun Liu, Shengyuan He, Shangqin Sun, Xinxin Zhang, Yan-yan He, Fei Quan, Bo Pang, Yun Xiao

Cancer immunology research

DOI

2023

Annotation of cell types (ACT): a convenient web server for cell type annotation

Fei Quan, Xin Liang, Mingjiang Cheng, Huan Yang, Kun Liu, Shengyuan He, Shangqin Sun, Menglan Deng, Yan-Zhen He, Wei Liu, Shuai Wang, Shuxian Zhao, Lantian Deng, Xiaobo Hou, Xinxin Zhang, Yun Xiao

Genome Medicine

DOI

2023

Dissecting cellular states of infiltrating microenvironment cells in melanoma by integrating single-cell and bulk transcriptome analysis

Aiai Shi, M. Yan, Bo Pang, Lin Pang, Yi-Han Wang, Yujia Lan, Xinxin Zhang, Jinyuan Xu, Y. Ping, Jing Hu

BMC Immunology

DOI

2022

CellMarker 2.0: an updated database of manually curated cell markers in human/mouse and web tools based on scRNA-seq data

Congxue Hu, Tengyue Li, Yingqi Xu, Xinxin Zhang, Feng Li, J. Bai, Jing Chen, Wenqi Jiang, Kaiyue Yang, Qi Ou, Xia Li, Peng Wang, Yunpeng Zhang

Nucleic Acids Res.

DOI

2022

Decoding the associations between cell functional states in head and neck cancer based on single-cell transcriptome.

Huating Yuan, M. Yan, Xin Liang, W. Liu, Shengyuan He, Shangqin Sun, Xinxin Zhang, Yujia Lan

Oral Oncology

DOI

2022

Revealing the functions of clonal driver gene mutations in patients based on evolutionary dependencies

Yujia Lan, W. Liu, Xiaobo Hou, Shuai Wang, Hao Wang, Menglan Deng, Gui-Yu Wang, Y. Ping, Xinxin Zhang

Human Mutation

DOI

2021

Systematic Assessment of Transcriptomic Biomarkers for Immune Checkpoint Blockade Response in Cancer Immunotherapy

Shangqin Sun, Li-Wen Xu, Xinxin Zhang, Lin Pang, Zhilin Long, Chunyu Deng, Jiali Zhu, Shuting Zhou, Linyun Wan, Bo Pang, Yun Xiao

Cancers

DOI

2021

Identifying Key Somatic Copy Number Alterations Driving Dysregulation of Cancer Hallmarks in Lower-Grade Glioma

Yao Zhou, Shuai Wang, Haoteng Yan, Bo Pang, Xinxin Zhang, Lin Pang, Yihan Wang, Jinyuan Xu, Jing Hu, Yujia Lan, Y. Ping

Frontiers in Genetics

DOI

2020

Transcriptome analysis reveals a reprogramming energy metabolism-related signature to improve prognosis in colon cancer

Xinxin Zhang, Jinyuan Xu, Yujia Lan, Fenghua Guo, Yun Xiao, Yixue Li, Xia Li

PeerJ

DOI

2020

Prognostic impact of a lymphocyte activation-associated gene signature in GBM based on transcriptome analysis

Yujia Lan, E. Zhao, Xinxin Zhang, Xiao-Jing Zhu, Linyun Wan, S. A, Y. Ping, Yihan Wang

PeerJ

DOI

2020

Combination of multiple tumor-infiltrating immune cells predicts clinical outcome in colon cancer.

Xinxin Zhang, Fei Quan, Jinyuan Xu, Yun Xiao, Xia Li, Yixue Li

Clinical Immunology

DOI

2019

Identifying Cancer Driver lncRNAs Bridged by Functional Effectors through Integrating Multi-omics Data in Human Cancers

Yong E. Zhang, Gao-Ming Liao, J. Bai, Xinxin Zhang, Li-Wen Xu, Chunyu Deng, M. Yan, Aimin Xie, Tao Luo, Zhilin Long, Yun Xiao, Xia Li

Molecular Therapy: Nucleic Acids

DOI

2019

Identifying mutual exclusivity across cancer genomes: computational approaches to discover genetic interaction and reveal tumor vulnerability

Yulan Deng, Shang-Yi Luo, Chunyu Deng, Tao Luo, Wenkang Yin, Hongyi Zhang, Yong E. Zhang, Xinxin Zhang, Yujia Lan, Y. Ping, Yun Xiao, Xia Li

Briefings Bioinform.

DOI

2019

IPEV: a web server for inferring pathogenic enhancers with variants

Guanxiong Zhang, Aimin Xie, J. Bai, Tao Luo, Huating Yuan, Gao-Ming Liao, Shang-Yi Luo, Jianlong Liao, Jinyuan Xu, Jian Shi, Yong E. Zhang, Xinxin Zhang, Tingting Zhao, Yun Xiao, Xia Li

DOI

2018

LnChrom: a resource of experimentally validated lncRNA–chromatin interactions in human and mouse

Fulong Yu, Guanxiong Zhang, Aiai Shi, Jing Hu, Feng Li, Xinxin Zhang, Yan Zhang, Jian Huang, Yun Xiao, Xia Li, Shujun Cheng

Database J. Biol. Databases Curation

DOI

2018

A pan‐cancer atlas of cancer hallmark‐associated candidate driver lncRNAs

Yulan Deng, Shang-Yi Luo, Xinxin Zhang, C. Zou, Huating Yuan, Gao-Ming Liao, Li-Wen Xu, Chunyu Deng, Yujia Lan, Tingting Zhao, Xu Gao, Yun Xiao, Xia Li

Molecular Oncology

DOI

2018

Sex difference of mutation clonality in diffuse glioma evolution

Hongyi Zhang, Jianlong Liao, Xinxin Zhang, E. Zhao, Xin Liang, Shang-Yi Luo, Jian Shi, Fulong Yu, Jinyuan Xu, Weitao Shen, Yixue Li, Yun Xiao, Xia Li

Neuro-Oncology

DOI

2018

TIP: A Web Server for Resolving Tumor Immunophenotype Profiling.

Li-Wen Xu, Chunyu Deng, Bo Pang, Xinxin Zhang, Wei Liu, Gao-Ming Liao, Huating Yuan, P. Cheng, Feng Li, Zhilin Long, M. Yan, Tingting Zhao, Yun Xiao, Xia Li

Cancer Research

DOI

2018

CellMarker: a manually curated resource of cell markers in human and mouse

Xinxin Zhang, Yujia Lan, Jinyuan Xu, Fei Quan, E. Zhao, Chunyu Deng, Tao Luo, Li-Wen Xu, Gao-Ming Liao, M. Yan, Y. Ping, Feng Li, Aiai Shi, J. Bai, Tingting Zhao, Xia Li, Yun Xiao

Nucleic Acids Res.

DOI

2017

SEECancer: a resource for somatic events in evolution of cancer genome

Hongyi Zhang, Shang-Yi Luo, Xinxin Zhang, Jianlong Liao, Fei Quan, E. Zhao, Chenfen Zhou, Fulong Yu, Wenkang Yin, Yunpeng Zhang, Yun Xiao, Xia Li

Nucleic Acids Res.

DOI

2017

Optimizing prognosis-related key miRNA-target interactions responsible for cancer metastasis

Hongying Zhao, Huating Yuan, Jing Hu, Chaohan Xu, Gao-Ming Liao, Wenkang Yin, Li-Wen Xu, Li Wang, Xinxin Zhang, Aiai Shi, Jing Li, Yun Xiao

OncoTarget

DOI

2016

Cooperative genomic alteration network reveals molecular classification across 12 major cancer types

Hongyi Zhang, Yulan Deng, Yong Zhang, Y. Ping, Hongying Zhao, Lin Pang, Xinxin Zhang, Li Wang, Chaohan Xu, Yun Xiao, Xia Li

Nucleic Acids Research

DOI

2016

A comprehensive overview of lncRNA annotation resources

Jinyuan Xu, J. Bai, Xinxin Zhang, Yanling Lv, Yonghui Gong, Ling Liu, Hongying Zhao, Fulong Yu, Y. Ping, Guanxiong Zhang, Yujia Lan, Yun Xiao, Xia Li

Briefings Bioinform.

DOI

张欣欣

精选作品

期刊论文

ZBED2调控JAK信号对卵巢癌细胞增殖、侵袭与迁移的影响

CancerSEA-X: A Single-cell Resource for Tumor Microenvironment Cell States Across over 30 Cancer Types.

Single-cell transcriptomes reveal cell-type-specific and sample-specific gene function in human cancer

Computational Quantification of Cancer Immunoediting.

Annotation of cell types (ACT): a convenient web server for cell type annotation

Dissecting cellular states of infiltrating microenvironment cells in melanoma by integrating single-cell and bulk transcriptome analysis

CellMarker 2.0: an updated database of manually curated cell markers in human/mouse and web tools based on scRNA-seq data

Decoding the associations between cell functional states in head and neck cancer based on single-cell transcriptome.

Revealing the functions of clonal driver gene mutations in patients based on evolutionary dependencies

Systematic Assessment of Transcriptomic Biomarkers for Immune Checkpoint Blockade Response in Cancer Immunotherapy

Identifying Key Somatic Copy Number Alterations Driving Dysregulation of Cancer Hallmarks in Lower-Grade Glioma

Transcriptome analysis reveals a reprogramming energy metabolism-related signature to improve prognosis in colon cancer

Prognostic impact of a lymphocyte activation-associated gene signature in GBM based on transcriptome analysis

Combination of multiple tumor-infiltrating immune cells predicts clinical outcome in colon cancer.

Identifying Cancer Driver lncRNAs Bridged by Functional Effectors through Integrating Multi-omics Data in Human Cancers

Identifying mutual exclusivity across cancer genomes: computational approaches to discover genetic interaction and reveal tumor vulnerability

IPEV: a web server for inferring pathogenic enhancers with variants

LnChrom: a resource of experimentally validated lncRNA–chromatin interactions in human and mouse

A pan‐cancer atlas of cancer hallmark‐associated candidate driver lncRNAs

Sex difference of mutation clonality in diffuse glioma evolution

TIP: A Web Server for Resolving Tumor Immunophenotype Profiling.

CellMarker: a manually curated resource of cell markers in human and mouse

SEECancer: a resource for somatic events in evolution of cancer genome

Optimizing prognosis-related key miRNA-target interactions responsible for cancer metastasis

Cooperative genomic alteration network reveals molecular classification across 12 major cancer types

A comprehensive overview of lncRNA annotation resources

研究方向