孙晓阳｜山东大学｜学者主页

2026

Thrombospondin 1 is associated with MASH and hepatic macrophage inflammatory responses via CD47

Qi-Ling Liu, Chenmin Fan, Bing'er Xu, Xin-Yu Yang, Xiaoyang Sun, Yuying Zhang, Shuqi Li, Miao Zhang, Xilei Ban, Guligeina Aikebaier, Ziping Bai, Wen-Fei Duan, Yang He, Hong-Mei Yan, Xin-Xia Chang, Mingfeng Xia, Xiaopeng Zhu, Xin Gao, Hua Bian

Metabolism and Target Organ Damage

DOI

2026

A cross-sectional study on the lifestyle of patients with Hashimoto’s thyroiditis

Shuai Ma, Peng Yu, Qi-Yu Chen, Miriayi Alimujiang, Dilidaer Muhanhali, Lei Zhang, Jiejie Zhao, Xiaoyang Sun, Yan Ling

BMC Endocrine Disorders

DOI

2025

Association Between Free Triiodothyronine and Diabetic Peripheral Neuropathy in Euthyroid Patients With Type 2 Diabetes.

Bing'er Xu, Xin-Yu Yang, Yu Ma, Yan-Feng Jiang, Yu-Xiao Jiang, Xu Li, Shuqi Li, Xiaoyang Sun, Xiaopeng Zhu, Chenmin Fan, Miao Zhang, Xilei Ban, Guligeina Aikebaier, Ziping Bai, W. Duan, Yang He, Xing-Dong Chen, Xin Gao, Jihong Dong, Mingfeng Xia, Hua Bian

Journal of Clinical Endocrinology and Metabolism

DOI

2025

Protein phosphatase 6 regulates metabolic dysfunction-associated steatohepatitis via the mTORC1 pathway.

Zheng-Shuai Liu, Shuang Wei, Yang Jiang, Weitong Su, Fengguang Ma, G. Cai, Yu-Xiao Liu, Xiaoyang Sun, Ling Lu, Wenguang Fu, Yong Xu, Ruijing Huang, Jian Li, Xu Lin, Aoyuan Cui, Mengwei Zang, Ai-Min Xu, Yu Li

Journal of Hepatology

DOI

2025

The role of irregular eating behaviors in metabolic dysfunction-associated steatotic liver disease: evidence from a multicenter cross-sectional study in China

Xing-Xing Ren, Miao Zhang, Xiaoyang Sun, Li-Li Zheng, Y. Bi, Qiang Li, Li-Rong Sun, Fusheng Di, Yu-Shan Xu, Da-Long Zhu, Yan-Yan Gao, Yu-Qian Bao, Yao Wang, Lanjie He, Xin Gao, Jian Gao, Mingfeng Xia, Hua Bian

Journal of Translational Medicine

DOI

2024

A metabolome-derived score predicts metabolic dysfunction-associated steatohepatitis and mortality from liver disease.

Qing-Xia Huang, S. Qadri, Hua Bian, Xiaoxuan Yi, Chen-Hao Lin, Xin-Yu Yang, Xiaopeng Zhu, Huandong Lin, Hongmei Yan, Xin-Xia Chang, Xiaoyang Sun, Shuai Ma, Qi Wu, Hailuan Zeng, Xiqi Hu, Yan Zheng, H. Yki-Järvinen, Xin Gao, Huiru Tang, Mingfeng Xia

Journal of Hepatology

DOI

2024

Increased serum β-hydroxybutyrate/acetoacetate ratio and aggravated histological liver inflammation in females with metabolic dysfunction-associated steatotic liver disease and polycystic ovary syndrome

Xiaopeng Zhu, Guligeina Aikebaier, Xilei Ban, Qing-Xia Huang, Hong-Mei Yan, Xin-Xia Chang, Xin-Yu Yang, Xiaoyang Sun, Hui-Ru Tang, Hua Bian, Xin Gao, Mingfeng Xia

Journal of Molecular Cell Biology

DOI

2024

Intermittent versus Continuous Calorie Restriction for Treatment of Metabolic Dysfunction-Associated Steatotic Liver Disease: A Randomized Clinical Trial.

Xiaoyang Sun, Fan Li, Hongmei Yan, Xin-Xia Chang, Xiu-Zhong Yao, Xin-Yu Yang, Sha-Sha Wu, Yue Suo, Xiaopeng Zhu, Chengyan Wang, Jian Gao, He Wang, Yan Chen, Mingfeng Xia, Hua Bian, Xin Gao

American Journal of Clinical Nutrition

DOI

2024

Association of vitamin D deficiency and subclinical diabetic peripheral neuropathy in type 2 diabetes patients

Xiaoyang Sun, Xin-Yu Yang, Xiaopeng Zhu, Yu Ma, Xu Li, Yuying Zhang, Qi-Ling Liu, Chenmin Fan, Miao Zhang, Bing'er Xu, Yanlan Xu, Xin Gao, Jihong Dong, Mingfeng Xia, Hua Bian

Frontiers in Endocrinology

DOI

2024

Association between fast eating speed and metabolic dysfunction-associated steatotic liver disease: a multicenter cross-sectional study and meta-analysis

Miao Zhang, Xiaoyang Sun, Xiaopeng Zhu, Li-Li Zheng, Y. Bi, Qiang Li, Li-Rong Sun, Fusheng Di, Yu-Shan Xu, Da-Long Zhu, Yan-Yan Gao, Yu-Qian Bao, Yao Wang, Lanjie He, Chenmin Fan, Xin Gao, Jian Gao, Mingfeng Xia, Hua Bian

Nutrition & Diabetes

DOI

2023

Intrahepatic osteopontin signaling by CREBZF defines a checkpoint for steatosis-to-NASH progression

Fengguang Ma, Yu-Xiao Liu, Zhi-Min Hu, Yaqian Xue, Zheng-Shuai Liu, G. Cai, Weitong Su, Zengpeng Zheng, Xia Fang, Xi Yan, Dong Ding, Xiaoyang Sun, Yang Jiang, Shuang Wei, Wen-Jing Li, Jiuxiang Zhao, Hai-Bing Zhang, Hong Li, D. Xiao, Cui-Ying Zhang, Hao Ying, Jun-Wei Qin, Xin Gao, Xiao-Zhen Dai, Wen-Guang Fu, Yong Xu, Yu Li, Aoyuan Cui

Hepatology

DOI

2023

Proline hydroxylation of CREB-regulated transcriptional coactivator 2 controls hepatic glucose metabolism

Yaqian Xue, Aoyuan Cui, Shuang Wei, Fengguang Ma, Zheng-Shuai Liu, Xia Fang, Shao-Feng Huo, Xiaoyang Sun, Wen-Jing Li, Zhi-Min Hu, Yu-Xiao Liu, G. Cai, Weitong Su, Jiuxiang Zhao, Xi Yan, Chen-Lin Gao, Jian Wen, Hai-Bing Zhang, Hong Li, Yi Liu, Xu Lin, Yong Xu, Wen-Guang Fu, Jing Fang, Yu Li

Proceedings of the National Academy of Sciences of the United States of America

DOI

2022

A novel model for detecting advanced fibrosis in patients with nonalcoholic fatty liver disease

Xin-Yu Yang, Mingfeng Xia, Xin-Xia Chang, Xiaopeng Zhu, Xiaoyang Sun, Yinqiu Yang, Liu Wang, Qi-Ling Liu, Yuying Zhang, Yanlan Xu, Huan-Dong Lin, Lin Liu, Xiu-Zhong Yao, Xiqi Hu, Jian Gao, Hong-Mei Yan, Xin Gao, Hua Bian

Diabetes/Metabolism Research Reviews

DOI

2022

Postprandial glucose is correlated with an increasing risk of liver fibrosis in Chinese patients with nonalcoholic fatty liver disease.

Xin-Xia Chang, Hua Bian, Mingfeng Xia, Xiaopeng Zhu, Xiaoyang Sun, Xin-Yu Yang, Jian Gao, Huan-Dong Lin, Hong-Mei Yan, Xin Gao

Diabetes & Metabolism

DOI

2021

Performance of liver stiffness measurements obtained with FibroScan is affected by glucose metabolism in patients with nonalcoholic fatty liver disease

Xin-Yu Yang, Xin-Xia Chang, Shengdi Wu, Xiaoyang Sun, Xiaopeng Zhu, Liu Wang, Yu-Shan Xu, Xiu-Zhong Yao, Shengxiang Rao, Xiqi Hu, Mingfeng Xia, Hua Bian, Hong-Mei Yan, Xin Gao

Lipids in Health and Disease

DOI

2021

Acute Effects of Sleeve Gastrectomy on Glucose Variability, Glucose Metabolism, and Ghrelin Response

Liu Wang, Chen-Ye Shi, Hong-Mei Yan, Mingfeng Xia, Xiaopeng Zhu, Xiaoyang Sun, Xin-Yu Yang, Huan Jiao, Hai-Fu Wu, W. Lou, Xin-Xia Chang, Xin Gao, Hua Bian

Obesity Surgery

DOI

2021

Hepatocyte CREBZF-osteopontin axis controls fibrosis in nonalcoholic steatohepatitis

Fengguang Ma, Yu-Xiao Liu, Zhi-Min Hu, Yaqian Xue, Zheng-Shuai Liu, G. Cai, Weitong Su, Zengpeng Zheng, Dong Ding, Xiaoyang Sun, Yang Jiang, Shuang Wei, Wen-Jing Li, Yong Xu, D. Xiao, Cui-Ying Zhang, Xin Gao, Xiao-Zhen Dai, Yu Li, Aoyuan Cui

DOI

2021

Diagnosis of Fibrosis Using Blood Markers and Logistic Regression in Southeast Asian Patients With Non-alcoholic Fatty Liver Disease

Chao Sang, Hong-Mei Yan, W. Chan, Xiaopeng Zhu, Tao Sun, Xin-Xia Chang, Mingfeng Xia, Xiaoyang Sun, Xiqi Hu, Xin Gao, W. Jia, Hua Bian, Tian-Lu Chen, G. Xie

Frontiers in Medicine

DOI

2021

332-OR: Pharmacological Inhibition of CREBZF Improves Insulin Resistance by Altering Activation of Macrophage in Adipose Tissue of Diet-Induced Obese Mice

Yu-Xiao Liu, Zhi-Min Hu, Zheng-Shuai Liu, Weitong Su, Zengpeng Zheng, Dong Ding, Fengguang Ma, Yaqian Xue, G. Cai, Shuang Wei, Zi-Xuan Wang, Xiaoyang Sun, Yang Jiang, Xiao-Zhen Dai, Yu Li, Aoyuan Cui

Diabetes

DOI

2020

Thrombospondin 1 improves hepatic steatosis in diet-induced insulin-resistant mice and is associated with hepatic fat content in humans

Jin-Yun Bai, Mingfeng Xia, Yaqian Xue, Fengguang Ma, Aoyuan Cui, Yi-Xuan Sun, Yamei Han, Xi Xu, Fei-Fei F. Zhang, Zhi-Min Hu, Zheng-Shuai Liu, Yu-Xiao Liu, G. Cai, Weitong Su, Xiaoyang Sun, Hai-Fu Wu, Hong-Mei Yan, Xin-Xia Chang, Xiqi Hu, Hua Bian, P. Xia, Jing Gao, Yu Li, Xin Gao

EBioMedicine

DOI

2020

Author response for "Osteocalcin and non‐alcoholic fatty liver disease: lessons from two population‐based cohorts and animal models"

Mingfeng Xia, Shun-Xing Rong, Xiaopeng Zhu, Hong-Mei Yan, Xin-Xia Chang, Xiaoyang Sun, Hailuan Zeng, Xiao-Ming Li, Linshan Zhang, Ling-Yan Chen, Li Wu, Hui Ma, Yu Hu, Wan-Yuan He, JiangKui Gao, Baishen Pan, Xiqi Hu, Huan-Dong Lin, Hua Bian, Xin Gao

DOI

2020

Investigation of Daily Glucose Profile of Inpatients in Non-endocrinology Departments in Chinese Population

Xiaoyang Sun, Ming-Hui Gui, Hui-Qun Huang, Hui-Hua Zhao, Hong-Mei Yan, Hua Bian, Xin Gao

Frontiers in Public Health

DOI

2020

Regional difference in the susceptibility of non-alcoholic fatty liver disease in China

Mingfeng Xia, Xiaoyang Sun, Li-Li Zheng, Y. Bi, Qiang Li, Li-Rong Sun, Fusheng Di, Hong Li, Da-Long Zhu, Yan-Yan Gao, Y. Bao, Yao Wang, Lanjie He, Bing-Jie Wu, Shanshan Wang, Jian Gao, Xin Gao, Hua Bian

BMJ Open Diabetes Research & Care

DOI

2020

Association between non-alcoholic fatty liver disease-associated hepatic fibrosis and bone mineral density in postmenopausal women with type 2 diabetes or impaired glucose regulation

Xiaopeng Zhu, Hong-Mei Yan, Xin-Xia Chang, Mingfeng Xia, Linshan Zhang, Liu Wang, Xiaoyang Sun, Xin-Yu Yang, Xin Gao, Hua Bian

BMJ Open Diabetes Research & Care

DOI

2020

Osteocalcin and Non‐Alcoholic Fatty Liver Disease: Lessons From Two Population‐Based Cohorts and Animal Models

Mingfeng Xia, Shun-Xing Rong, Xiaopeng Zhu, Hong-Mei Yan, Xin-Xia Chang, Xiaoyang Sun, Hailuan Zeng, Xiao-Ming Li, Linshan Zhang, Ling-Yan Chen, Li Wu, Hui Ma, Yu Hu, Wan-Yuan He, Jian Gao, Baishen Pan, Xiqi Hu, Huan-Dong Lin, Hua Bian, Xin Gao

Journal of Bone and Mineral Research

DOI

2019

Berberine attenuates nonalcoholic hepatic steatosis through the AMPK-SREBP-1c-SCD1 pathway.

Xiaopeng Zhu, Hua Bian, Liu Wang, Xiaoyang Sun, Xi Xu, Hong-Mei Yan, Mingfeng Xia, Xin-Xia Chang, Yan Lu, Yu Li, P. Xia, Xiaoying Li, Xin Gao

Free Radical Biology & Medicine

DOI

2019

FoxO3 regulates hepatic triglyceride metabolism via modulation of the expression of sterol regulatory-element binding protein 1c

Liu Wang, Xiaopeng Zhu, Xiaoyang Sun, Xin-Yu Yang, Xin-Xia Chang, Mingfeng Xia, Yan Lu, P. Xia, Hong-Mei Yan, Hua Bian, Xin Gao

Lipids in Health and Disease

DOI

2018

Metformin attenuates triglyceride accumulation in HepG2 cells through decreasing stearyl-coenzyme A desaturase 1 expression

Xiaopeng Zhu, Hong-Mei Yan, Mingfeng Xia, Xin-Xia Chang, Xi Xu, Liu Wang, Xiaoyang Sun, Yan Lu, Hua Bian, Xiaoying Li, Xin Gao

Lipids in Health and Disease

DOI

2017

体重是否是“稳态”调控的?——来自Rcan2的启示

公倩倩，李士威，孙晓阳

《中国科学:生命科学》

2016

A disputed evidence on obesity: comparison of the effects of Rcan2−/− and Rps6kb1−/− mutations on growth and body weight in C57BL/6J mice

Jing Zhao, Shiwei Li, Qian-qian Gong, Ling-cui Ding, Yecheng Jin, Jian Zhang, Jiangang Gao, Xiaoyang Sun

Journal of Zhejiang University SCIENCE B

DOI

2004

富含脯氨酸小蛋白-2在小鼠子宫中的表达及调节

谈寅飞，孙晓阳，唐爽，朴允尚，王雁玲

《生物化学与生物物理进展》

2003

Wnt信号通路与哺乳动物生殖

孙晓阳，王雁玲

《生物化学与生物物理进展》

2003

用少量样本进行抑制性消减杂交

孙晓阳，谈寅飞，唐爽，王雁玲

《生物化学与生物物理进展》

孙晓阳

精选作品

期刊论文

Thrombospondin 1 is associated with MASH and hepatic macrophage inflammatory responses via CD47

A cross-sectional study on the lifestyle of patients with Hashimoto’s thyroiditis

Association Between Free Triiodothyronine and Diabetic Peripheral Neuropathy in Euthyroid Patients With Type 2 Diabetes.

Protein phosphatase 6 regulates metabolic dysfunction-associated steatohepatitis via the mTORC1 pathway.

The role of irregular eating behaviors in metabolic dysfunction-associated steatotic liver disease: evidence from a multicenter cross-sectional study in China

A metabolome-derived score predicts metabolic dysfunction-associated steatohepatitis and mortality from liver disease.

Increased serum β-hydroxybutyrate/acetoacetate ratio and aggravated histological liver inflammation in females with metabolic dysfunction-associated steatotic liver disease and polycystic ovary syndrome

Intermittent versus Continuous Calorie Restriction for Treatment of Metabolic Dysfunction-Associated Steatotic Liver Disease: A Randomized Clinical Trial.

Association of vitamin D deficiency and subclinical diabetic peripheral neuropathy in type 2 diabetes patients

Association between fast eating speed and metabolic dysfunction-associated steatotic liver disease: a multicenter cross-sectional study and meta-analysis

Intrahepatic osteopontin signaling by CREBZF defines a checkpoint for steatosis-to-NASH progression

Proline hydroxylation of CREB-regulated transcriptional coactivator 2 controls hepatic glucose metabolism

A novel model for detecting advanced fibrosis in patients with nonalcoholic fatty liver disease

Postprandial glucose is correlated with an increasing risk of liver fibrosis in Chinese patients with nonalcoholic fatty liver disease.

Performance of liver stiffness measurements obtained with FibroScan is affected by glucose metabolism in patients with nonalcoholic fatty liver disease

Acute Effects of Sleeve Gastrectomy on Glucose Variability, Glucose Metabolism, and Ghrelin Response

Hepatocyte CREBZF-osteopontin axis controls fibrosis in nonalcoholic steatohepatitis

Diagnosis of Fibrosis Using Blood Markers and Logistic Regression in Southeast Asian Patients With Non-alcoholic Fatty Liver Disease

332-OR: Pharmacological Inhibition of CREBZF Improves Insulin Resistance by Altering Activation of Macrophage in Adipose Tissue of Diet-Induced Obese Mice

Thrombospondin 1 improves hepatic steatosis in diet-induced insulin-resistant mice and is associated with hepatic fat content in humans

Author response for "Osteocalcin and non‐alcoholic fatty liver disease: lessons from two population‐based cohorts and animal models"

Investigation of Daily Glucose Profile of Inpatients in Non-endocrinology Departments in Chinese Population

Regional difference in the susceptibility of non-alcoholic fatty liver disease in China

Association between non-alcoholic fatty liver disease-associated hepatic fibrosis and bone mineral density in postmenopausal women with type 2 diabetes or impaired glucose regulation

Osteocalcin and Non‐Alcoholic Fatty Liver Disease: Lessons From Two Population‐Based Cohorts and Animal Models

Berberine attenuates nonalcoholic hepatic steatosis through the AMPK-SREBP-1c-SCD1 pathway.

FoxO3 regulates hepatic triglyceride metabolism via modulation of the expression of sterol regulatory-element binding protein 1c

Metformin attenuates triglyceride accumulation in HepG2 cells through decreasing stearyl-coenzyme A desaturase 1 expression

体重是否是“稳态”调控的?——来自Rcan2的启示

A disputed evidence on obesity: comparison of the effects of Rcan2−/− and Rps6kb1−/− mutations on growth and body weight in C57BL/6J mice

富含脯氨酸小蛋白-2在小鼠子宫中的表达及调节

Wnt信号通路与哺乳动物生殖

用少量样本进行抑制性消减杂交

会议论文

恒河猴着床点基因差异表达分析