柴人杰｜东南大学｜学者主页

2026

老年性听力损失与认知障碍

王秋菊，余力生，时海波，张娇，胡亦新，陈晓巍，柴人杰，孙宇，蔡跃新，付小龙，吴萧男，王宁宇，贺祖宏，孙岩，杨军，王大勇，冀飞，陈钢钢，宋蒙涛，王硕，李佳楠，赵立东

《临床耳鼻咽喉头颈外科杂志》

2026

A non-canonical function of glutathione to suppress ferroptosis via FSP1

Jing Han, Yu-Dan Zhang, Shuo Liu, Li Yang, Shuang-Li Sun, Ben Zhang, Ao-kun Liu, Ling-Fan Zhu, Rong Wang, Dandan Song, Xiao Zhuang, Yi-Jia Gao, Jingxin Li, Wen-Fei Li, Rong‐Rong He, Heng-Xing Zhou, Yu Lu, Shi-Qing Feng, Renjie Chai, Bo Chu

Cell

精选作品

期刊论文

老年性听力损失与认知障碍

A non-canonical function of glutathione to suppress ferroptosis via FSP1

Piezoelectric Nanofibrous Scaffolds for Promoting the Growth of Spiral Ganglion Neurons via Acoustic Stimulation

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Biomimetic Multichannel 3D MXene Nanofiber Sponges for Peripheral Nerve Regeneration

Rational and computation-assisted engineering of a compact and efficient CRISPR-Cas12f genome editor

MITF-SCD1 lipid metabolic axis prevents ouabain-induced spiral ganglion neuron ferroptosis and hearing loss

Efficient and safe transduction of cochlear outer hair cells in adult mice with AAV2.7m8-Myo15

Correction to: Knockdown of Foxg1 in supporting cells increases the trans‑differentiation of supporting cells into hair cells in the neonatal mouse cochlea

Sensory Neuroscience—Charting the Course From Molecular Mechanisms to Clinical Translation

Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction

Recent advancements in improving cross-species applicability of bioengineered AAV capsids

The Roles of Tbx2 in Cochlear Development and Auditory Function

Multifunctional Inverse Opal Nerve Guidance Conduits Loaded with Mesenchymal Stem Cells for Peripheral Nerve Repair

Gene Editing Technologies for Hereditary Hearing Loss: Prospects and Challenges

Bilayer nerve guidance conduits for continuous delivery of NGF@ZIF-8 nanoparticles for peripheral nerve injury repair

Conditional knockout of Dkk3 drives Lgr5+ progenitor reprogramming into hair cells in the mouse cochlea

Next-generation 3D bioprinted inner ear organoids

Advances in GPCRs Associated With Wnt Signaling Within the Auditory System

Regulation of Tmem30b-mediated apical membrane homeostasis in auditory outer hair cells is critical for hearing

Advances in the Treatment of Sensorineural Hearing Loss: From Traditional Therapies to Stem Cell and Gene Therapies

Human promoter-driven AAV tools enable precision gene therapy targeting cochlear hair cells

Developing Inner Ear Organoids in Ultrasound-Activated Piezoelectric Hydrogel for Assessing Ototoxicity

[Genetic hearing loss GJB2 c.109G>A (p.Val37Ile) consultation key points and clinical significance].

Multifunctional Self‐Assembling Peptide System for Preventing Noise‐Induced Hearing Loss

Auditory Neuropathy: Challenges and Significant Progress in Diagnosis and Treatment

Precise and efficient DNA base editing restores normal hearing in adult DFNB9 mouse model

Dysregulation of Serpinb6a-Gch1 axis contributes to DFNB91 deafness that is amendable to gene therapies

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Molecular heterogeneity of the non-human primate cochlea

Magnetic Mesoporous Nanoparticles Loaded with Lycium barbarum Glycopeptide for Targeted Therapy of Noise‐Triggered Auditory Dysfunction

遗传性听力损失人工耳蜗植入的基因诊断预后评价专家共识

基于AAV的遗传性耳聋基因治疗的基础和临床研究进展

难治性内耳病面临的问题与挑战

A force-sensitive adhesion GPCR is required for equilibrioception

Single‐Nucleus Transcriptomics Uncovers Xaf1‐Driven PANoptosis as a Therapeutic Target in Aminoglycoside‐Induced Hearing Loss

Single-cell profiling identifies hair cell SLC35F1 deficiency as a signature of primate cochlear aging

Small Extracellular Vesicles Orchestrate Cisplatin‐Induced Ototoxicity: Potential Biomarker and Targets Discovery

mRNA metabolism regulator human antigen R (HuR) regulates age-related hearing loss in aged mice

Multicargo Porous Cochlear Electrode Coating for Antifibrosis After Cochlear Implantation

Targeting Programmed Cell Death in Acquired Sensorineural Hearing Loss: Ferroptosis, Necroptosis, and Pyroptosis

Biomaterial-based drug delivery systems in the treatment of inner ear disorders

AAV-Sparcl1 promotes hair cell regeneration by increasing supporting cell plasticity

The New Era: Emerging Opportunities, Revolutionary Advances, and Challenges Ahead—The Future Road of Sensory Neuroscience

Lycium barbarum Glycopeptide Alleviates Neomycin‐Induced Ototoxicity by Inhibiting Tryptophan Hydroxylase‐Mediated Serotonin Biosynthesis

Combined AAV-mediated specific Gjb2 expression restores hearing in DFNB1 mouse models

Conditional Overexpression of Serpine2 Promotes Hair Cell Regeneration from Lgr5+ Progenitors in the Neonatal Mouse Cochlea

GSDMD-mediated mitochondrial dysfunction in marginal cells: A potential driver of inflammation and stria vascularis damage in CIHL

Metabolomic and Cellular Mechanisms of Drug‐Induced Ototoxicity and Nephrotoxicity: Therapeutic Implications of Uric Acid Modulation

OTOF-related gene therapy: a new way but a long road ahead

RONIN/HCF1‐TFEB Axis Protects Against D‐Galactose‐Induced Cochlear Hair Cell Senescence Through Autophagy Activation

Artificial Intelligence‐Based Approaches for AAV Vector Engineering

A biomarker framework for auditory system aging: the Aging Biomarker Consortium consensus statement

Wnt signalling facilitates neuronal differentiation of cochlear Frizzled10-positive cells in mouse cochlea via glypican 6 modulation

Corrigendum to “Conductive PS inverse opals for regulating proliferation and differentiation of neural stem cells” [Engineered Regeneration 4 (2023) 214-221]

Engineering vascularized inner ear organoids: Challenges and advances in recapitulating the cochlear microenvironment

Conductive Nerve Guidance Conduits Loaded With Adipose Mesenchymal Stem Cells for Peripheral Nerve Regeneration

Hearing Loss: From Basic to Clinical Science

Cidea Targeting Protects Cochlear Hair Cells and Hearing Function From Drug‐ and Noise‐Induced Damage

Bmi1 controls auditory sensory epithelial cell proliferation through genome-wide H3K27me3 modifications

Engineering neural recovery: Micro/nano-structured materials for nerve regeneration

Neural stem cell-loaded biohybrid hydrogel improves cochlear implants by electrode-neural coupling and neural regeneration

The force-sensing GPCR LPHN2 is indispensable for normal auditory function

International expert consensus on gene therapy for hereditary hearing loss: Based on clinical trials

Inner Ear Organoids: A Hydrogel-Based Platform for Drug Screening and Deafness Modeling

Bioactive hydrogels for the reconstruction of sensorineural hearing loss

Aligned nanofiber-based responsive sponge scaffolds for peripheral nerve regeneration

Treating Hearing Loss: From Cochlear Implantation to Gene Therapy

Optimized in vivo base editing restores auditory function in a DFNA15 mouse model

Cutting‐Edge Advancements in Physical Stimulation for Spiral Ganglion Neuron Protection and Regeneration

Multifaceted Role of RIMBP2 in Promoting Hearing in Murine Cochlear Hair Cells

Blood–labyrinth barrier damage mediated by granzymes from cytotoxic lymphocytes results in hearing loss in systemic lupus erythematosus

Targeting NLRP3/caspase-1/GSDMD to treat inner ear injury from labyrinthine hemorrhage

Establishment of a Cochlear Organoid Platform for Remodeling the Extracellular Matrix

Author Correction: mRNA metabolism regulator human antigen R (HuR) regulates age-related hearing loss in aged mice

AAV gene therapy for autosomal recessive deafness 9: a single-arm trial

遗传性耳聋基因治疗临床指南

遗传性耳聋临床诊疗研究进展