谢君｜复旦大学｜学者主页

2025

Immunoinformatic Prediction of HIV-1 Glycoprotein gp120 and Nef Epitopes Conjugated to HBsAg-Binding Protein (SBP) to Induce the Humoral and Cellular Immune Response

Arslan Habib, Xinyi Xu, Jun Xie, Naishuo Zhu

International Journal of Molecular Sciences

2024

PD-L1 targeted peptide demonstrates potent antitumor and immunomodulatory activity in cancer immunotherapy

Yulai Liang, Huazao Luo, Xue Li, Shuang Liu, Arslan Habib, Baoxiu Liu, Jiansheng Huang, Jingbo Wang, Yi Han, Bo Hu, Liuhai Zheng, Jun Xie, Naishuo Zhu

Frontiers in Immunology

DOI

2024

Immunoinformatic Identification of Multiple Epitopes of gp120 Protein of HIV-1 to Enhance the Immune Response against HIV-1 Infection

Arslan Habib, Yulai Liang, Xinyi Xu, Naishuo Zhu, Jun Xie

International Journal of Molecular Sciences

DOI

2024

OST-01, a natural product from Baccharis coridifolia, targets c-Myc-dependent ribogenesis in acute myeloid leukemia

Hyunjun Kang, Dinh Hoa Hoang, Melissa Valerio, K. Pathak, Lian-Jun Zhang, Ralf Buettner, Fang Chen, Katrina Estrella, William Graff, Zhuo Li, Jun Xie, David A Horne, Ya-Huei Kuo, Bin Zhang, P. Pirrotte, L. Nguyen, Guido Marcucci

Leukemia

DOI

2023

Pharmacological profiling of a berbamine derivative for lymphoma treatment

Senlin Xu, Shunquan Wu, Mingfeng Zhang, Jun Xie, Mingsheng Lin, Lihua Jin, Jiawei Zhang, Yangmeng Wang, Mingjie Fan, Zhipeng Fang, Wei-Ni Li, Ching Ouyang, David Kwon, N. Que, Zhi-Rou Li, Jin-Ge Mao, Hao-Nan Chen, J. Harris, Xi-Wei Wu, Jun Wu, Hong-Wei Yin, Wing C. Chan, David Horne, Wen-Dong Huang

Blood Advances

DOI

2023

Design, Synthesis, Computational and Biological Evaluation of Novel Structure Fragments Based on Lithocholic Acid (LCA)

Jiangling Peng, M. Fan, Kelly X. Huang, Lina A Huang, Yangmeng Wang, Runkai Yin, Hanyi Zhao, Senlin Xu, Hongzhi Li, Alon Agua, Jun Xie, D. Horne, F. Kandeel, Wen-Dong Huang, Junfeng Li

Molecules

DOI

2022

Identification of candidate hub genes correlated with the pathogenesis, diagnosis, and prognosis of prostate cancer by integrated bioinformatics analysis

Tianyi Wei, Yulai Liang, Claire Anderson, Ming Zhang, Naishuo Zhu, Jun Xie

Translational Cancer Research

DOI

2022

Targeting MYC and BCL2 by a natural compound for “double-hit” lymphoma

Xiao-Qian Liu, Senlin Xu, Jia-Wei Zhang, M. Fan, Jun Xie, Bing-Feng Zhang, Hongzhi Li, Guo-Hua Yu, Ying-Hui Liu, Yuan-Feng Zhang, J. Song, D. Horne, W. Chan, X. Chu, Wen-Dong Huang

Hematological Oncology

DOI

2021

Potent Anticancer Effects of Epidithiodiketopiperazine NT1721 in Cutaneous T Cell Lymphoma

Min Lin, C. Kowolik, Jun Xie, Sushma Yadav, L. Overman, D. Horne

Cancers

DOI

2021

Correction: Lin et al. Potent Anticancer Effects of Epidithiodiketopiperazine NT1721 in Cutaneous T Cell Lymphoma. Cancers 2021, 13, 3367

Mingsheng Lin, C. Kowolik, Jun Xie, Sushma Yadav, L. Overman, D. Horne

Cancers

DOI

2020

Proteomics analysis identified TPI1 as a novel biomarker for predicting recurrence of intrahepatic cholangiocarcinoma

Wenlong Yu, Guanzhen Yu, Hui Fen Dong, Ke Chen, Jun Xie, Hua Yu, Yuan Ji, Guang-Shun Yang, Aijun Li, Wen‐Ming Cong, Guang‐Zhi Jin

Journal of Gastroenterology

DOI

2020

Six Novel Biomarkers for Diagnosis and Prognosis of Esophageal squamous cell carcinoma: validated by scRNA-seq and qPCR

Liuhai Zheng, Linzhi Li, Jun Xie, Hai Dan Jin, Naishuo Zhu

Journal of Cancer

DOI

2020

Cellular UAP56 interacts with the HBx protein of the hepatitis B virus and is involved in viral RNA nuclear export in hepatocytes

Bo Hu, Lili Yu, Naishuo Zhu, Jun Xie

Experimental Cell Research

DOI

2020

Targeting FTO suppresses cancer stem cell maintenance and immune evasion

R. Su, Lei Dong, Yang-Chan Li, Min Gao, Li Han, M. Wunderlich, Xiaolan Deng, Hongzhi Li, Yue Huang, Lei Gao, Chen-Ying Li, Zhicong Zhao, S. Robinson, B. Tan, Ying Qing, Xi Qin, Emily A. Prince, Jun Xie, H. Qin, Wei Li, Chao Shen, Jie Sun, Prakash Kulkarni, Hengyou Weng, Huilin Huang, Zhen-Hua Chen, Bin Zhang, Xi-Wei Wu, M. Olsen, M. Müschen, G. Marcucci, R. Salgia, Ling Li, A. Fathi, Ze-Juan Li, J. Mulloy, M. Wei, D. Horne, Jianjun Chen

Cancer Cell

DOI

2019

荧光素酶标记小鼠结肠癌细胞建立活体成像移植瘤模型

罗华灶，李雪，依含，谢君，朱乃硕

《中国免疫学杂志》

2019

Meta-analysis: diagnostic accuracy of the citrullinated peptides derived from fibrinogen and vimentin in rheumatoid arthritis

Xue Li, Zhenni Wang, Yi Han, Jun Xie, Naishuo Zhu

Clinical Rheumatology

DOI

2019

Evolution of the Cholesterol Biosynthesis Pathway in Animals

Tingting Zhang, Dongwei Yuan, Jun Xie, Yongxing Lei, Jianguo Li, Gangqi Fang, Ling Tian, Jiacheng Liu, Yingying Cui, Min Zhang, Youli Xiao, Yong-Zhen Xu, Jianzhen Zhang, Maoyan Zhu, Shuai Zhan, Sheng Li

Molecular Biology and Evolution

DOI

2019

Effective Novel Fto Inhibitors Show Potent Anti-Cancer Efficacy and Suppress Drug Resistance

R. Su, Lei Dong, Yang-Chan Li, Li Han, Min Gao, M. Wunderlich, Xiaolan Deng, Hongzhi Li, Lei Gao, Chen-Ying Li, Sean Robison, B. Tan, Ying Qing, Xi Qin, Emily A. Prince, Jun Xie, H. Qin, Yue Huang, Wei Li, Chao Shen, Jie Sun, K. Prakash, Hengyou Weng, Huilin Huang, Zhen-Hua Chen, Bin Zhang, Xi-Wei Wu, M. Olsen, M. Müschen, G. Marcucci, Sujith Ravi, Ling Li, Cai-Guang Yang, Ze-Juan Li, J. Mulloy, M. Wei, D. Horne, Jian-Jun Chen

Blood

DOI

2019

Attenuation of hedgehog/GLI signaling by NT1721 extends survival in pancreatic cancer

C. Kowolik, Min Lin, Jun Xie, L. Overman, D. Horne

Journal of experimental & clinical cancer research : CR

DOI

2018

α-烯醇化酶的翻译后修饰对类风湿关节炎免疫诊断价值

王珍妮，薛鸾，谢君，朱乃硕

《现代免疫学》

2018

HBV感染者肝细胞样本的关键基因和信号通路的生物信息学挖掘

李林芝，谢君，朱乃硕

《生物信息学》

2018

适应性免疫新兴免疫检查点的相关研究进展

罗华灶，李雪，谢君，朱乃硕

《免疫学杂志》

2018

Specific zinc finger‐induced methylation of PD‐L1 promoter inhibits its expression

Xue Li, Zhenni Wang, Jiansheng Huang, Huazao Luo, Sibo Zhu, Han Yi, Liuhai Zheng, Bo Hu, Lili Yu, Lingzhi Li, Jun Xie, Naishuo Zhu

FEBS Open Bio

DOI

2018

Nasal immunization with RSV F and G protein fragments conjugated to an M cell-targeting ligand induces an enhanced immune response and protection against RSV infection

Inam Ullah Khan, Jiansheng Huang, Xue Li, Jun Xie, Naishuo Zhu

Antiviral Research

DOI

2018

Mechanically interlocked functionalization of monoclonal antibodies

K. Bzymek, James W. Puckett, C. Zer, Jun Xie, Yue-Long Ma, Jeremy D. King, Leah H Goodstein, K. Avery, D. Colcher, Gagandeep Singh, D. Horne, John C. Williams

Nature Communications

DOI

2017

Phage Display–Derived Ligand for Mucosal Transcytotic Receptor GP-2 Promotes Antigen Delivery to M Cells and Induces Antigen-Specific Immune Response

Inam Ullah Khan, Jiansheng Huang, Rui Liu, Jingbo Wang, Jun Xie, Naishuo Zhu

SLAS DISCOVERY

DOI

2017

Caspase polymorphisms and prognosis of hepatocellular carcinoma

Song Zhang, Qianyi Xiao, Zhuqing Shi, Guopeng Yu, Xiaopin Ma, Haitao Chen, Pengyin Zhang, Suqin Shen, Hexige Saiyin, Taoyang Chen, Peixin Lu, Neng-Jin Wang, Weihua Ren, Peng Huang, Jun Xie, Carly Conran, Shusen Zheng, Long Yu, Jianfeng Xu, Deke Jiang

PLoS ONE

DOI

2017

Systems Pharmacology-based strategy to screen new adjuvant for hepatitis B vaccine from Traditional Chinese Medicine Ophiocordyceps sinensis

Jingbo Wang, Rui Liu, Baoxiu Liu, Yan Yang, Jun Xie, Naishuo Zhu

Scientific Reports

DOI

2017

A Pre-Clinical Safety Evaluation of SBP (HBsAg-Binding Protein) Adjuvant for Hepatitis B Vaccine

Jingbo Wang, Caixia Su, Rui Liu, Baoxiu Liu, Inam Ullah Khan, Jun Xie, Naishuo Zhu

PLoS ONE

DOI

2016

Shizukaol D, a Dimeric Sesquiterpene Isolated from Chloranthus serratus, Represses the Growth of Human Liver Cancer Cells by Modulating Wnt Signalling Pathway

Lisha Tang, Hengrui Zhu, Xianmei Yang, Fang Xie, Jingtao Peng, Deke Jiang, Jun Xie, Meiyan Qi, Long Yu

PLoS ONE

DOI

2016

NT1721, a novel epidithiodiketopiperazine, exhibits potent in vitro and in vivo efficacy against acute myeloid leukemia

C. Kowolik, Min Lin, Jun Xie, L. Overman, D. Horne

OncoTarget

DOI

2015

甲壳素亲和层析在人g2型溶菌酶制备中的应用

黄鹏，李文姝，谢君，鲍建瑛，曹晓娥，徐一新

《免疫学杂志》

2015

Tricyclic Analogues of Epidithiodioxopiperazine Alkaloids with Promising In Vitro and In Vivo Antitumor Activity

M. Baumann, André P. Dieskau, B. M. Loertscher, Mary C. Walton, S. Nam, Jun Xie, D. Horne, L. Overman

Chemical Science

DOI

2014

Phylogenetic analysis of CDK and cyclin proteins in premetazoan lineages

Lihuan Cao, Fang Chen, Xianmei Yang, Weijin Xu, Jun Xie, Long Yu

BMC Evolutionary Biology

DOI

2014

Photocleavable Dimerizer for the Rapid Reversal of Molecular Trap Antagonists*

Shubbir Ahmed, Jun Xie, D. Horne, John C. Williams

Journal of Biological Chemistry

DOI

2012

Abstract 864: Novel synthetic berbamine derivatives inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells

S. Nam, Jun Xie, A. Perkins, Yue-Long Ma, Fan Yang, Jun Wu, Yan Wang, Rong-Zhen Xu, Wen-Dong Huang, D. Horne, R. Jove

DOI

2012

Identification of Oct4-activating compounds that enhance reprogramming efficiency

Wen-Dong Li, E. Tian, Zhao-Xia Chen, Guo-Qiang Sun, Peng Ye, Su Yang, David M. Lu, Jun Xie, T. Ho, W. Tsark, Charles Wang, D. Horne, A. Riggs, M. L. Richard Yip, Yan-Hong Shi

Proceedings of the National Academy of Sciences of the United States of America

DOI

2012

Novel synthetic derivatives of the natural product berbamine inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells

S. Nam, Jun Xie, A. Perkins, Yue-Long Ma, Fan Yang, Jun Wu, Yan Wang, Rong-Zhen Xu, Wen-Dong Huang, David Horne, R. Jove

Molecular Oncology

DOI

2011

Relationship between TP73 polymorphism (G4C14–A4T14) and cancer risk: A meta-analysis based on literatures

Xiaojia Yu, Fang Fang, Jun Xie

Gene

DOI

2011

Asymmetric synthesis of the core structure of leucosceptroids A-D.

Jun Xie, Yue-Long Ma, D. Horne

Journal of Organic Chemistry

DOI

2010

Total synthesis of the proposed structure of iriomoteolide-1a.

Jun Xie, Yue-Long Ma, D. Horne

Chemical Communications

DOI

2009

Asymmetric synthesis of the C7-C23 fragment of iriomoteolide-1a.

Jun Xie, Yue-Long Ma, D. Horne

Organic Letters

DOI

2009

Stereoselective synthesis of iriomoteolide-1a hemiketal core

Jun Xie, D. Horne

DOI

2008

Characterization of a Supercluster of SnoRNA Genes from Rice Genome

Jun Xie, Fang Fang, Hairong Hu, Xu Feng, Qi Wu

International Conference on Biomedical Engineering and Informatics (BMEI)

DOI

2005

Expression and characterization of the carboxyl esterase Rv3487c from Mycobacterium tuberculosis

Min Zhang, Jiadong Wang, Zuo-feng Li, Jun Xie, Yanping Yang, Yang Zhong, Honghai Wang

Protein Expression and Purification

DOI

精选作品

期刊论文

Immunoinformatic Prediction of HIV-1 Glycoprotein gp120 and Nef Epitopes Conjugated to HBsAg-Binding Protein (SBP) to Induce the Humoral and Cellular Immune Response

PD-L1 targeted peptide demonstrates potent antitumor and immunomodulatory activity in cancer immunotherapy

Immunoinformatic Identification of Multiple Epitopes of gp120 Protein of HIV-1 to Enhance the Immune Response against HIV-1 Infection

OST-01, a natural product from Baccharis coridifolia, targets c-Myc-dependent ribogenesis in acute myeloid leukemia

Pharmacological profiling of a berbamine derivative for lymphoma treatment

Design, Synthesis, Computational and Biological Evaluation of Novel Structure Fragments Based on Lithocholic Acid (LCA)

Identification of candidate hub genes correlated with the pathogenesis, diagnosis, and prognosis of prostate cancer by integrated bioinformatics analysis

Targeting MYC and BCL2 by a natural compound for “double-hit” lymphoma

Potent Anticancer Effects of Epidithiodiketopiperazine NT1721 in Cutaneous T Cell Lymphoma

Correction: Lin et al. Potent Anticancer Effects of Epidithiodiketopiperazine NT1721 in Cutaneous T Cell Lymphoma. Cancers 2021, 13, 3367

Proteomics analysis identified TPI1 as a novel biomarker for predicting recurrence of intrahepatic cholangiocarcinoma

Six Novel Biomarkers for Diagnosis and Prognosis of Esophageal squamous cell carcinoma: validated by scRNA-seq and qPCR

Cellular UAP56 interacts with the HBx protein of the hepatitis B virus and is involved in viral RNA nuclear export in hepatocytes

Targeting FTO suppresses cancer stem cell maintenance and immune evasion

荧光素酶标记小鼠结肠癌细胞建立活体成像移植瘤模型

Meta-analysis: diagnostic accuracy of the citrullinated peptides derived from fibrinogen and vimentin in rheumatoid arthritis

Evolution of the Cholesterol Biosynthesis Pathway in Animals

Effective Novel Fto Inhibitors Show Potent Anti-Cancer Efficacy and Suppress Drug Resistance

Attenuation of hedgehog/GLI signaling by NT1721 extends survival in pancreatic cancer

α-烯醇化酶的翻译后修饰对类风湿关节炎免疫诊断价值

HBV感染者肝细胞样本的关键基因和信号通路的生物信息学挖掘

适应性免疫新兴免疫检查点的相关研究进展

Specific zinc finger‐induced methylation of PD‐L1 promoter inhibits its expression

Nasal immunization with RSV F and G protein fragments conjugated to an M cell-targeting ligand induces an enhanced immune response and protection against RSV infection

Mechanically interlocked functionalization of monoclonal antibodies

Phage Display–Derived Ligand for Mucosal Transcytotic Receptor GP-2 Promotes Antigen Delivery to M Cells and Induces Antigen-Specific Immune Response

Caspase polymorphisms and prognosis of hepatocellular carcinoma

Systems Pharmacology-based strategy to screen new adjuvant for hepatitis B vaccine from Traditional Chinese Medicine Ophiocordyceps sinensis

A Pre-Clinical Safety Evaluation of SBP (HBsAg-Binding Protein) Adjuvant for Hepatitis B Vaccine

Shizukaol D, a Dimeric Sesquiterpene Isolated from Chloranthus serratus, Represses the Growth of Human Liver Cancer Cells by Modulating Wnt Signalling Pathway

NT1721, a novel epidithiodiketopiperazine, exhibits potent in vitro and in vivo efficacy against acute myeloid leukemia

甲壳素亲和层析在人g2型溶菌酶制备中的应用

Tricyclic Analogues of Epidithiodioxopiperazine Alkaloids with Promising In Vitro and In Vivo Antitumor Activity

Phylogenetic analysis of CDK and cyclin proteins in premetazoan lineages

Photocleavable Dimerizer for the Rapid Reversal of Molecular Trap Antagonists*

Abstract 864: Novel synthetic berbamine derivatives inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells

Identification of Oct4-activating compounds that enhance reprogramming efficiency

Novel synthetic derivatives of the natural product berbamine inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells

Relationship between TP73 polymorphism (G4C14–A4T14) and cancer risk: A meta-analysis based on literatures

Asymmetric synthesis of the core structure of leucosceptroids A-D.

Total synthesis of the proposed structure of iriomoteolide-1a.

Asymmetric synthesis of the C7-C23 fragment of iriomoteolide-1a.

Stereoselective synthesis of iriomoteolide-1a hemiketal core

Characterization of a Supercluster of SnoRNA Genes from Rice Genome

Expression and characterization of the carboxyl esterase Rv3487c from Mycobacterium tuberculosis

研究方向