百晓学者学者目录

靳瑾

副研究员，清华大学

精选作品

期刊论文

2026

Neuro-immune axis regulates humoral immune response: an interdisciplinary exploration from bench to bedside

Xin-Tao Mao, Wen-ping Li, Yi-Yuan Li, Jin Jin

Scientia Sinica Vitae

DOI

2025

NAT10-mediated acetylation of NIK mRNA in B cells promotes IgA production

Wan-Jun Jiang, Xin-Tao Mao, Wen-ping Li, N. Jin, Yu Wang, G. Guan, Jin Jin, Yi-Yuan Li

EMBO Reports

DOI

2025

Author Correction: TNF inhibitors target a mevalonate metabolite/TRPM2/calcium signaling axis in neutrophils to dampen vasculitis in Behçet’s disease

Meng-Hao Zhang, Na Kang, Xin Yu, Xiaoyang Zhang, Qinghui Duan, Xianqiang Ma, Qiancheng Zhao, Zhimian Wang, Xiao'ou Wang, Ye-Ling Liu, Yu-Xiao Zhang, Can Zhu, Ruiyu Gao, Xin Min, Cui-Feng Li, Jin Jin, Qian Cao, Rongbei Liu, Xiao-Yin Bai, Hong Yang, Li-Dan Zhao, Jin-Jing Liu, Hua Chen, Yong-Hui Zhang, Wan-Li Liu, Wen-Jie Zheng

Nature Communications

DOI

2024

N-acetyltransferase 10 is implicated in the pathogenesis of cycling T cell-mediated autoimmune and inflammatory disorders in mice

Wen-ping Li, Xin-Tao Mao, Jiaokui Xie, Jie-yu Li, Bao-qin Liu, Le-Xi Wu, Bing Yang, Yi-Yuan Li, Jin Jin

Nature Communications

DOI

2024

TNF inhibitors target a mevalonate metabolite/TRPM2/calcium signaling axis in neutrophils to dampen vasculitis in Behçet’s disease

Meng-Hao Zhang, Na Kang, Xin Yu, Xiaoyang Zhang, Qinghui Duan, Xianqiang Ma, Qiancheng Zhao, Zhimian Wang, Xiao'ou Wang, Ye-Ling Liu, Yu-Xiao Zhang, Can Zhu, Ruiyu Gao, Xin Min, Cui-Feng Li, Jin Jin, Qian Cao, Rongbei Liu, Xiao-Yin Bai, Hong Yang, Li-Dan Zhao, Jin-Jing Liu, Hua Chen, Yong-Hui Zhang, Wan-Li Liu, Wen-Jie Zheng

Nature Communications

DOI

2024

The hope of engineered T cells to cure diseases of the central nervous system

Jin Jin

Precision Medicine and Engineering

DOI

2022

XAF1 prevents hyperproduction of type I interferon upon viral infection by targeting IRF7

Bao-qin Liu, Rongbei Liu, Wen-ping Li, Xin-Tao Mao, Yi-Ning Li, Tao Huang, Hao-Li Wang, Hao-Tian Chen, Jiang-Yan Zhong, Bing Yang, R. Chai, Q. Cao, Jin Jin, Yi-Yuan Li

EMBO Reports

DOI

2022

Macrophage-mediated immune response aggravates hearing disfunction caused by the disorder of mitochondrial dynamics in cochlear hair cells.

Yuan Zhang, Xiaolong Fu, Yi-Yuan Li, Wen Li, Guo-Dong Hong, Si-Wei Guo, Yu Xiao, Ziyi Liu, Shu-Qin Ding, Xiu-Li Bi, Fanglei Ye, Jin Jin, R. Chai

Human Molecular Genetics

DOI

2022

The clinical features and potential mechanisms of cognitive disorders in peripheral autoimmune and inflammatory diseases

Ke-Qi Fan, Tao Huang, Jian-shuai Yu, Yi-Yuan Li, Jin Jin

Fundamental Research

DOI

2021

A double-edged sword of immuno-microenvironment in cardiac homeostasis and injury repair

K. Sun, Yi-Yuan Li, Jin Jin

Signal Transduction and Targeted Therapy

DOI

2021

GPR15–C10ORF99 functional pairing initiates colonic Treg homing in amniotes

Jin-Xia Song, Huaping Zheng, Jingwen Xue, Jian Liu, Qian Sun, Wei Yang, Fang Liu, Xi Xiang, Kai He, You-Nan Chen, Jingqiu Cheng, Wei Li, Jin Jin, Juergen Brosius, Cheng Deng

EMBO Reports

DOI

2021

Single-nucleotide methylation specifically represses type I interferon in antiviral innate immunity

Zheng-Jun Gao, Wen-ping Li, Xin-Tao Mao, Tao Huang, Hao-Li Wang, Yi-Ning Li, Bao-qin Liu, Jiang-Yan Zhong, R. Chai, Jin Jin, Yi-Yuan Li

Journal of Experimental Medicine

DOI

2021

Substrate-specific recognition of IKKs mediated by USP16 facilitates autoimmune inflammation

Jian-shuai Yu, Tao Huang, Yu Zhang, Xin-Tao Mao, Ling-Jie Huang, Yi-Ning Li, Ting-ting Wu, Jiang-Yan Zhong, Q. Cao, Yi-Yuan Li, Jin Jin

Science Advances

DOI

2021

Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn's disease.

Ling-Jie Huang, Xin-Tao Mao, Yi-Yuan Li, Danping Liu, Ke-Qi Fan, Rongbei Liu, Ting-ting Wu, Hao-Li Wang, Yu Zhang, Bing Yang, Cun-Qi Ye, Jiang-Yan Zhong, R. Chai, Q. Cao, Jin Jin

Immunity

DOI

2021

The Disorder of Mitochondrial Dynamics Causes Deafness By Promoting Macrophage-Mediated Hair Cell Death

Yuan Zhang, Xiaolong Fu, Yi-Yuan Li, Guo-Dong Hong, Peipei Li, Si-Jia Guo, Fanglei Ye, Jin Jin, R. Chai

DOI

2021

P040 USP16 regulates p65 activation in macrophages and promotes the inflammatory-carcinoma transformation process in IBD patients

Yu Zhang, Chencheng Wang, L. Yao, Ming Li, Jin Jin, Qingpeng Cao

DOI

2020

The essential functions of mitochondrial dynamics in immune cells

Jiaokui Xie, Yi-Yuan Li, Jin Jin

Cellular & Molecular Immunology

DOI

2020

The essential function of IL-33 in metabolic regulation.

Wen-Ping Li, Yi-Yuan Li, Jin Jin

Acta Biochimica et Biophysica Sinica

DOI

2020

Ubiquitination modification: critical regulation of IRF family stability and activity

Bao-Qin Liu, Jin Jin, Yi-Yuan Li

Science China Life Sciences

DOI

2020

The Physiological functions of IKK-selective substrate identification and their critical roles in diseases

Jian-shuai Yu, Jin Jin, Yi-Yuan Li

DOI

2020

Author Correction: The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling

Jin Jin, Yichuan Xiao, Jae-Hoon Chang, Jiayi Yu, Hongbo Hu, R. Starr, George C. Brittain, Mikyoung Chang, Xuhong Cheng, Shao-Cong Sun

Nature Immunology

DOI

2019

Stress-Induced Metabolic Disorder in Peripheral CD4+ T Cells Leads to Anxiety-like Behavior.

Ke-Qi Fan, Yi-Yuan Li, Hao-Li Wang, Xin-Tao Mao, Jin-Xin Guo, Fei Wang, Ling-Jie Huang, Yi-Ning Li, Xiang-Yu Ma, Zheng-Jun Gao, Wei Chen, Dan-Dan Qian, Wenpeng Xue, Q. Cao, Lei Zhang, Liangduo Shen, Long Zhang, Chao Tong, Jiang-Yan Zhong, Wei Lu, Ling Lu, Ke-Ming Ren, Gui-Sheng Zhong, Yuan Wang, Ming-Liang Tang, Xin-hua Feng, R. Chai, Jin Jin

Cell

DOI

2019

USP16-mediated deubiquitination of calcineurin A controls peripheral T cell maintenance.

Yu Zhang, Rongbei Liu, Q. Cao, Ke-Qi Fan, Ling-Jie Huang, Jian-shuai Yu, Zheng-Jun Gao, Tao Huang, Jiang-Yan Zhong, Xin-Tao Mao, Fei Wang, P. Xiao, Yuan Zhao, Xin-Hua Feng, Yi-Yuan Li, Jin Jin

Journal of Clinical Investigation

DOI

2019

P037 USP16-mediated deubiquitination of calcineurin A controls peripheral T cells maintenance and attenuates intestinal inflammation

Yan Zhang, R. Liu, Ke-Qi Fan, L. Huang, Zheng-Jun Gao, Tao Huang, Jiang-Yan Zhong, Xin-Tao Mao, Fei Wang, P. Xiao, Y. Zhao, Yi-Yuan Li, Xin-Hua Feng, Jin Jin, Q. Cao

Journal of Crohn's & Colitis

DOI

2019

CRL4DCAF2 is required for mature T-cell expansion via Aurora B-regulated proteasome activity.

Ke-Qi Fan, Fei Wang, Yi-Yuan Li, Lu Chen, Zheng-Jun Gao, Yu Zhang, Jinhzu Duan, Tao Huang, Jiang-Yan Zhong, Rongbei Liu, Xin-Tao Mao, Hengyu Fan, Xing Guo, Jin Jin

Journal of Autoimmunity

DOI

2019

Cell type-specific function of TRAF2 and TRAF3 in regulating type I IFN induction

Xiaoping Xie, Jin Jin, Lele Zhu, Zuliang Jie, Yanchuan Li, Bao-Yu Zhao, Xuhong Cheng, Ping-Wei Li, Shao-Cong Sun

Cell & Bioscience

DOI

2018

CRL4DCAF2 negatively regulates IL-23 production in dendritic cells and limits the development of psoriasis

Tao Huang, Zheng-Jun Gao, Yu Zhang, Ke-Qi Fan, Fei Wang, Yi-Yuan Li, Jiang-Yan Zhong, Heng-Yu Fan, Q. Cao, Ji-Yong Zhou, Yichuan Xiao, Hongbo Hu, Jin Jin

Journal of Experimental Medicine

DOI

2018

Macrophage/microglial Ezh2 facilitates autoimmune inflammation through inhibition of Socs3

Xingli Zhang, Yan Wang, Jia Yuan, Ni Li, Si-Yu Pei, Jing Xu, Xuan Luo, Chao-Ming Mao, Jun-Li Liu, Tao Yu, Shucheng Gan, Qianqian Zheng, Yinming Liang, Wei-Xiang Guo, Ju Qiu, G. Constantin, Jin Jin, J. Qin, Yichuan Xiao

Journal of Experimental Medicine

DOI

2018

Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus

Jun-Li Liu, Xin-Fang Huang, Shumeng Hao, Yan Wang, Manman Liu, Jing Xu, Xingli Zhang, Tao Yu, Shucheng Gan, Dongfang Dai, Xuan Luo, Qing-Yan Lu, Chao-Ming Mao, Yan-Yun Zhang, N. Shen, Bin Li, Mingzhu Huang, Xiaodong Zhu, Jin Jin, Xuhong Cheng, Shao-Cong Sun, Yichuan Xiao

Nature Communications

DOI

2017

Mitochondrial dynamics controls anti-tumour innate immunity by regulating CHIP-IRF1 axis stability

Zheng-Jun Gao, Yi-Yuan Li, Fei Wang, Tao Huang, Ke-Qi Fan, Yu Zhang, Jiang-Yan Zhong, Q. Cao, Tong Chao, Jun-Ling Jia, Shuo Yang, Long Zhang, Yichuan Xiao, Ji-Yong Zhou, Xin-Hua Feng, Jin Jin

Nature Communications

DOI

2017

The kinase TBK1 functions in dendritic cells to regulate T cell homeostasis, autoimmunity, and antitumor immunity

Yichuan Xiao, Qiang Zou, Xiaoping Xie, Ting Liu, Haiyan S Li, Zuliang Jie, Jin Jin, Hongbo Hu, G. Manyam, Li Zhang, Xuhong Cheng, Hui Wang, I. Marié, D. Levy, S. Watowich, Shao-Cong Sun

Journal of Experimental Medicine

DOI

2016

Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination

Hongbo Hu, Hui Wang, Yichuan Xiao, Jin Jin, Jae-Hoon Chang, Qiang Zou, Xiaoping Xie, Xuhong Cheng, Shao-Cong Sun

Journal of Experimental Medicine

DOI

2016

Epigenetic regulation of Il12 and Il23 gene expression and autoimmune inflammation by the deubiquitinase Trabid

Jin Jin, Xiaoping Xie, Yichuan Xiao, Hongbo Hu, Qiang Zou, Xuhong Cheng, Shao-Cong Sun

Nature Immunology

DOI

2015

Peli1 negatively regulates type I interferon induction and antiviral immunity in the CNS

Yichuan Xiao, Jin Jin, Qiang Zou, Hongbo Hu, Xuhong Cheng, Shao-Cong Sun

Cell & Bioscience

DOI

2015

T cell intrinsic USP15 deficiency promotes excessive IFN-γ production and an immunosuppressive tumor microenvironment in MCA-induced fibrosarcoma

Qiang Zou, Jin Jin, Yichuan Xiao, Xiaofei Zhou, Hongbo Hu, Xuhong Cheng, Nasser Kazimi, S. Ullrich, Shao-Cong Sun

Cell Reports

DOI

2015

T cell development involves TRAF3IP3-mediated ERK signaling in the Golgi

Qiang Zou, Jin Jin, Yichuan Xiao, Hongbo Hu, Xiao-Fei Zhou, Zuliang Jie, Xiaoping Xie, James Y. H. Li, Xuhong Cheng, Shao-Cong Sun

Journal of Experimental Medicine

DOI

2015

FKBP51 employs both scaffold and isomerase functions to promote NF-κB activation in melanoma

S. Romano, Yichuan Xiao, M. Nakaya, Anna D'Angelillo, Mikyoung Chang, Jin Jin, F. Hausch, M. Masullo, Xixi Feng, M. Romano, Shao-Cong Sun

Nucleic Acids Research

DOI

2015

Proinflammatory TLR signaling is regulated by a TRAF2-dependent proteolysis mechanism in macrophages

Jin Jin, Yichuan Xiao, Hongbo Hu, Qiang Zou, Yanchuan Li, Yan-Pan Gao, Wei Ge, Xuhong Cheng, Shao-Cong Sun

Nature Communications

DOI

2014

USP15 stabilizes MDM2 to mediate cancer cell survival and inhibit antitumor T cell responses

Qiang Zou, Jin Jin, Hongbo Hu, Haiyan S Li, S. Romano, Yichuan Xiao, M. Nakaya, Xiao-Fei Zhou, Xuhong Cheng, Pei-Rong Yang, G. Lozano, Cheng-Ming Zhu, S. Watowich, S. Ullrich, Shao-Cong Sun

Nature Immunology

DOI

2014

Noncanonical NF-κB Pathway Controls the Production of Type I Interferons in Antiviral Innate Immunity

Jin Jin, Hongbo Hu, Haiyan S Li, Jiayi Yu, Yichuan Xiao, George C. Brittain, Qiang Zou, Xuhong Cheng, Frédérick A. Mallette, S. Watowich, Shao-Cong Sun

Immunity

DOI

2014

TPL2 mediates autoimmune inflammation through activation of the TAK1 axis of IL-17 signaling

Yichuan Xiao, Jin Jin, Mikyoung Chang, M. Nakaya, Hongbo Hu, Qiang Zou, Xiao-Fei Zhou, George C. Brittain, Xuhong Cheng, Shao-Cong Sun

Journal of Experimental Medicine

DOI

2014

STAT3 restrains RANK- and TLR4-mediated signaling by suppressing expression of the E2 ubiquitin ligase Ubc13

Hui-Yuan Zhang, Hongbo Hu, N. Greeley, Jin Jin, Allison J Matthews, E. Ohashi, Maurício S. Caetano, Haiyan S Li, Xuefeng Wu, P. Mandal, J. Mcmurray, S. Moghaddam, Shao-Cong Sun, S. Watowich

Nature Communications

DOI

2014

TRAF3 regulates the effector function of regulatory T cells and humoral immune responses

Jae-Hoon Chang, Hongbo Hu, Jin Jin, N. Puebla-Osorio, Yichuan Xiao, B. Gilbert, R. Brink, S. Ullrich, Shao-Cong Sun

Journal of Experimental Medicine

DOI

2013

Otud7b controls noncanonical NF-κB activation via deubiquitination of TRAF3

Hongbo Hu, George C. Brittain, Jae-Hoon Chang, N. Puebla-Osorio, Jin Jin, A. Zal, Yichuan Xiao, Xuhong Cheng, Mikyoung Chang, Yang-Xin Fu, Tomasz Zal, Cheng-Ming Zhu, Shao-Cong Sun

Nature

DOI

2013

Regulation of NF-κB in Autoimmunity

Shao-Cong Sun, Jae-Hoon Chang, Jin Jin

Trends in immunology

DOI

2013

Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation

Yichuan Xiao, Jin Jin, Mikyoung Chang, Jae-Hoon Chang, Hongbo Hu, Xiao-Fei Zhou, George C. Brittain, Christine Stansberg, Ø. Torkildsen, Xiaodong Wang, R. Brink, Xuhong Cheng, Shao-Cong Sun

Nature Medicine

DOI

2012

Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells

Jae-Hoon Chang, Yichuan Xiao, Hongbo Hu, Jin Jin, Jiayi Yu, Xiao-Fei Zhou, Xuefeng Wu, H. Johnson, S. Akira, M. Pasparakis, Xuhong Cheng, Shao-Cong Sun

Nature Immunology

DOI

2012

TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling

Jin Jin, Yichuan Xiao, Jae-Hoon Chang, Jiayi Yu, Hongbo Hu, R. Starr, George C. Brittain, Mikyoung Chang, Xuhong Cheng, Shao-Cong Sun

Nature Immunology

DOI

此主页由公开资料整理，尚未经学者本人认领。