焦仁杰｜广州医科大学｜学者主页

精选作品

期刊论文

2026

Xgr is involved in body size control in Drosophila through promoting glucose uptake in the Malpighian tubules

Zhiwei Lin, Zihao He, Jianfeng Guo, Xiaofang Ji, Ze Hu, Yingsen Tang, Chuanxian Wei, Jiyong Liu, Wenqi Wu, Jun Ma, Renjie Jiao

Journal of Genetics and Genomics

2026

Exploring innate immunity through the lens of fruit fly models

Di Chen, Hua Cai, Chuanxian Wei, Renjie Jiao, Jean-Luc Imler, Dominique Ferrandon, Jules A Hoffmann

hLife

2026

From Drosophila to mammals: The evolutionarily conserved homeodomain protein Engrailed affects the antitumor innate immune response

Jieqing Huang, X.Y. Lan, Xiaoming Huang, Yuntong Yuan, Mo Liu, Jiyong Liu, J S Chen, Zhenhui Ye, Ziming Wei, Yuqiang Chen, Zihao Deng, Yuhong Zhang, Yanzhen He, Xiaojing Zhou, Zhenming Cao, Mengyu Jiu, Renjie Jiao, Hua Cai, Jules A. Hoffmann, DJ Chen

Proceedings of the National Academy of Sciences

DOI

2026

α-Ketoglutarate couples cellular metabolism to developmental growth via hydroxylation-dependent degradation of Yorkie

Tao He, Yongchang Zeng, Jie Zhou, Yuqi Tian, Donggui Wang, Jingchao Ma, Jiyong Liu, Wenqi Wu, Chuanxian Wei, Renjie Jiao

Cell Reports

DOI

2025

Functional characterization of Paillotin: an immune peptide regulated by the Immune deficiency (Imd) pathway with pathogen-specific roles in Drosophila immunity

Yao Tian, Xiaojing Yue, Renjie Jiao, Mark Austin Hanson, Bruno Lemaitre

Proceedings Of The Royal Society B-Biological Sciences，Vol. 292, No. 20540

DOI

2025

溶质载体蛋白调控免疫应答的研究进展

苏方，魏传贤，焦仁杰

《中国基础科学》

2025

PGRP-SC-mediated innate immune memory against pathogenic bacteria in Drosophila

Zi-Hao Deng, Jia-Zhen Luo, Yufu Zhang, Chen Li, Shixin Deng, Jiazhi He, Zihao He, Wenqi Wu, Renjie Jiao, Ji-Yong Liu

hLife

DOI

2023

Gain of function screen of PATs reveals an essential role of Hip14 in Drosophila host defense

Zhu Deng, Hui Chen, Lingling Xiao, Haolan Jin, Qinhao Zhang, Renjie Jiao, Chuanxian Wei

Journal of Genetics and Genomics

2022

Shaggy regulates tissue growth through Hippo pathway in Drosophila

Honggang Wu, Nannan Zhu, Jiyong Liu, Jun Ma, Renjie Jiao

Science China Life Sciences

2019

围绕基础学科共建，初探免疫学学科建设

汤娟娟，李孜，焦仁杰，马宁芳，付晓东，刘金保

《广州医科大学学报》

2019

果蝇蛋白质激酶Pitslre通过调控抗菌肽表达参与天然免疫反应

刘燕，谢欣雨，陈赖强，苏方，王欢，焦仁杰，刘继勇

《中国生物化学与分子生物学报》

DOI

2019

HDAC6 regulates lipid droplet turnover in response to nutrient deprivation via p62-mediated selective autophagy

Yan Yan, Hao Wang, Chuanxian Wei, Yuanhang Xiang, Xuehong Liang, Chung-Weng Phang, Renjie Jiao

Journal of Genetics and Genomics

2018

果蝇HDAC6通过维持PLIN2的蛋白稳态抑制衰老相关的异位脂肪堆积

Yan Yan, Hao Wang, Minling Hu, Lifen Jiang, Yang Wang, Pingsheng Liu, Xuehong Liang, Jiyong Liu, Changqing Li, Anya Lindstr?m-Battle, Sin Man Lam, Guanghou Shui, Wu-Min Deng, 焦仁杰

《科学新闻》

2017

Anything impossible with CRISPR/Cas9?

Renjie Jiao, Caixia Gao

Science China Life Sciences

2017

CRISPR/Cas9无所不能?

焦仁杰，高彩霞

《中国科学:生命科学》

2016

从随机突变到精确编辑:果蝇基因组编辑技术的发展及演化

苏方，黄宗靓，郭雅文，焦仁杰，李孜，陈建明，刘继勇

《遗传》

2016

The CRISPR/Cas9 Genome Editing Revolution

Renjie Jiao, Caixia Gao

Journal of Genetics and Genomics

2015

Ecdysone and Insulin Signaling Play Essential Roles in Readjusting the Altered Body Size Caused by the dGPAT4 Mutation in Drosophila

Yan Yan, Hao Wang, Hanqing Chen, Anya Lindstrm-Battle, Renjie Jiao

Journal of Genetics and Genomics

2013

TALEN or Cas9-Rapid,Efficient and Specific Choices for Genome Modifications

Chuanxian Wei, Jiyong Liu, Zhongsheng Yu, Bo Zhang, Guanjun Gao, Renjie Jiao

Journal of Genetics and Genomics

2012

黑腹果蝇dCAF-1-p55突变引起果蝇发育迟缓和染色体不稳定性(英文)

吴青华，刘继勇，陈毅序，焦仁杰

《生物化学与生物物理进展》

2011

SUMO化信号途径对JNK信号通路活性的调控

黄海，朱南南，焦仁杰

《生物化学与生物物理进展》

2008

DNA修复的表观遗传学调控

黄庆雷，焦仁杰

《生物化学与生物物理进展》

2007

基因表达调控中国科学家谈科学

焦仁杰

《科学观察》

会议论文

2015

果蝇Hippo信号通路上游调控因子Expanded翻译后修饰的功能研究

李常青，戴斐，张洪涛，胡昊，邓武民，焦仁杰

《遗传多样性：前沿与挑战——中国的遗传学研究（2013-2015）——2015中国遗传学会大会论文摘要汇编》

2012

基于TALEN介导的一种高效、简便、特异地获得黑腹果蝇突变体的方法

刘继勇，李常青，于忠胜，黄鹏，伍洪刚，魏传贤，朱南南，沈延，陈毅序，张博，邓武民，焦仁杰

《第二届模式生物与人类健康研讨会会议论文集》

2012

蛋白修饰调控果蝇Wee活性的研究

李常青，陈菡青，焦仁杰

《第二届模式生物与人类健康研讨会会议论文集》

2011

sbo Regulates Lifespan through its Function in Ubiquinone Synthesis in Drosophila

刘继勇，吴青华，焦仁杰

《中国的遗传学研究——遗传学进步推动中国西部经济与社会发展——2011年中国遗传学会大会》

2009

Chromatin Assembly Factor 1 is Essential for Maintaining Heterochromatin Stability

黄海，于忠胜，焦仁杰

《“基因、进化与生理功能多样性”海内外学术研讨会暨中国生理学会第七届比较生理学学术会议》

预印本

2026

Cyclic dinucleotides induce chromatin remodeling associated with long-lasting antiviral protection in flies and bees

Hua Cai, Yuqiang Chen, Ziming Wei, Xianlong Ai, Cardamone Francesco, Jingxian Zhou, Antonin Thiébaut, Junhui Zhang, Jingxian Huang, Yin Ting, He Wenhao, Huimin Deng, Huang Zhanxin, Lin Xiaoqing, Tan Long, Xiaohan Zhang, Liu Jiyong, Mo Liu, DJ Chen, Renjie Jiao, Robert Michael Waterhouse, Carine Meignin, Nicola Iovino, João Trindade Marques, Jean‐Luc Imler

Research Square

DOI

研究方向

果蝇天然免疫调节机制细胞信号与代谢、衰老对免疫应答的调控

此主页由公开资料整理，尚未经学者本人认领。

精选作品

期刊论文

Xgr is involved in body size control in Drosophila through promoting glucose uptake in the Malpighian tubules

Exploring innate immunity through the lens of fruit fly models

From Drosophila to mammals: The evolutionarily conserved homeodomain protein Engrailed affects the antitumor innate immune response

α-Ketoglutarate couples cellular metabolism to developmental growth via hydroxylation-dependent degradation of Yorkie

Functional characterization of Paillotin: an immune peptide regulated by the Immune deficiency (Imd) pathway with pathogen-specific roles in Drosophila immunity

溶质载体蛋白调控免疫应答的研究进展

PGRP-SC-mediated innate immune memory against pathogenic bacteria in Drosophila

Gain of function screen of PATs reveals an essential role of Hip14 in Drosophila host defense

Shaggy regulates tissue growth through Hippo pathway in Drosophila

围绕基础学科共建，初探免疫学学科建设

果蝇蛋白质激酶Pitslre通过调控抗菌肽表达参与天然免疫反应

HDAC6 regulates lipid droplet turnover in response to nutrient deprivation via p62-mediated selective autophagy

果蝇HDAC6通过维持PLIN2的蛋白稳态抑制衰老相关的异位脂肪堆积

Anything impossible with CRISPR/Cas9?

CRISPR/Cas9无所不能?

从随机突变到精确编辑:果蝇基因组编辑技术的发展及演化

The CRISPR/Cas9 Genome Editing Revolution

Ecdysone and Insulin Signaling Play Essential Roles in Readjusting the Altered Body Size Caused by the dGPAT4 Mutation in Drosophila

TALEN or Cas9-Rapid,Efficient and Specific Choices for Genome Modifications

黑腹果蝇dCAF-1-p55突变引起果蝇发育迟缓和染色体不稳定性(英文)

SUMO化信号途径对JNK信号通路活性的调控

DNA修复的表观遗传学调控

基因表达调控 中国科学家谈科学

会议论文

果蝇Hippo信号通路上游调控因子Expanded翻译后修饰的功能研究

基于TALEN介导的一种高效、简便、特异地获得黑腹果蝇突变体的方法

蛋白修饰调控果蝇Wee活性的研究

sbo Regulates Lifespan through its Function in Ubiquinone Synthesis in Drosophila

Chromatin Assembly Factor 1 is Essential for Maintaining Heterochromatin Stability

预印本

Cyclic dinucleotides induce chromatin remodeling associated with long-lasting antiviral protection in flies and bees

研究方向

基因表达调控中国科学家谈科学