百晓学者学者目录

蔡霞

复旦大学

精选作品

期刊论文

2026

Maleic acid adjuvates BCG to induce CD4+CD8+ T cells and sterilize tuberculosis

Chen-Yue Shi, Hong-Yu Cheng, Xiao-Li Feng, Xin-Yu Cao, Hong-Jie Liu, Qi Liu, Lu Zhang, Yuan-Na Cheng, Cheng Peng, Jin-Yang Zhang, Qiao-Jiang Yang, Ke-Jing Dong, Yu-Li Gao, Xin-Yi Hu, Yu-Dan Liu, Y. Bian, Shen-Zhi Li, Yi-Fan Yang, Lin Wang, Jie Wang, Xiao-Cheng Huang, Xia Cai, Di Qu, Ming-Hua Li, Hua Yang, Bao-Xue Ge

bioRxiv

DOI

2026

Rapid Construction and Characterization of Infectious cDNA Clones and Reporter Viruses of Enteroviruses, Including Enterovirus A71 and Coxsackievirus B5, with Systematic Identification of Critical Determinants for Successful Reporter Virus Generation

Hao Zheng, Tong Zhao, Meixian Fu, Zirui Niu, Yifan Xing, Xia Cai, Jian-Er Long

Viruses

DOI

2026

Mycobacterium tuberculosis modulates phosphorylation of host ATP6V1E1 to promote intracellular survival

Jian-Xia Chen, F. Tang, Lian-Hua Qin, Weijun Fang, Liru Guan, Xiang-Yang Wu, Hao-Hao Li, Yongjia Duan, Fei Wang, Cheng Peng, Zhonghua Liu, Jie Wang, Xiao-Cheng Huang, Lin Wang, Hua Yang, Li Wang, Wei Sha, Xia Cai, Liangdong Lyu, Hai-Peng Liu, Feng Liu, Bao-Xue Ge, R. Zheng

Nature Communications

DOI

2026

An IRES-like cis-acting element located within the EV-A71 coding region drives translation independent of the 5′-IRES and modulates viral fitness through regulated binding of viral RNA to 3D polymerase

Yifan Xing, Qi Liu, Meixian Fu, Hao Zheng, Tong Zhao, Xi-Xi Chen, Xia Cai, Jian-Er Long

Journal of Virology

DOI

2025

Nucleic Acid Aptamers for Human Norovirus GII.4 and GII.17 Virus-Like Particles (VLPs) Exhibit Specific Binding and Inhibit VLPs from Entering Cells

Chao Cheng, Minjia Sun, Jingjing Li, Yi Xue, Xia Cai, Jing Liu, Xiao-Lian Wang, Shouhong Xu, Youhua Xie, Junqi Zhang

International Journal of Nanomedicine

DOI

2025

Genetic determinants of Mycobacterium tuberculosis adaptation and drug efficacy during stationary phase growth

Xiaojie Shi, Kun-Xiong Shi, Fu Han, Li Wang, Xia Cai, Guoping Zhao, Wei Sha, Liang-Dong Lyu

Microbiology Spectrum

DOI

2024

In Vitro Culture of Human Norovirus in the Last 20 Years

Chao Cheng, Xia Cai, Jingjing Li, Xiaomeng Zhang, Youhua Xie, Junqi Zhang

Biomedicines

DOI

2024

Mycobacterium tuberculosis produces d-serine under hypoxia to limit CD8+ T cell-dependent immunity in mice

Hong-Yu Cheng, Zhe Ji, Yang Wang, Shen-Zhi Li, Tianqi Tang, Fei Wang, Cheng Peng, Xiang-Yang Wu, Yuan-Na Cheng, Zhonghua Liu, Ming-Tong Ma, Jie Wang, Xiao-Cheng Huang, Lin Wang, Lian-Hua Qin, Hai-Peng Liu, Jian-Xia Chen, Rui-Juan Zheng, Carl G. Feng, Xia Cai, Di Qu, Li-Lin Ye, Hua Yang, Bao-Xue Ge

Nature Microbiology

DOI

2023

Mycobacterium tuberculosis suppresses host DNA repair to boost its intracellular survival.

Shanshan Liu, Liru Guan, Cheng Peng, Yuan-Na Cheng, Hong-Yu Cheng, Fei Wang, Ming-Tong Ma, Rui-Juan Zheng, Zhe Ji, Pengfei Cui, Yefei Ren, Liru Li, Chen-Yue Shi, Jie Wang, Xiao-Cheng Huang, Xia Cai, Di Qu, Hai-Ping Zhang, Z. Mao, Hai-Peng Liu, Peng Wang, W. Sha, Hua Yang, Lin Wang, Bao-Xue Ge

Cell Host and Microbe

DOI

2022

Survival of SARS‐CoV‐2 in artificial seawater and on the surface of inanimate materials

Zhi-Ping Sun, Siqi Yang, Xia Cai, Wen-Dong Han, Gaowei Hu, Yun Qian, Yuyan Wang, Rong Zhang, You-Hua Xie, D. Qu

Journal of Medical Virology

DOI

2021

Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants

Ting-Ting Li, Xiao-Jian Han, C. Gu, Hangtian Guo, Huajun Zhang, Ying-Ming Wang, Chao Hu, Kai Wang, Fengjiang Liu, F. Luo, Ya-Nan Zhang, Jie-Li Hu, Wang Wang, Shenglong Li, Y. Hao, M. Shen, Jingjing Huang, Y. Long, Shu-Yi Song, R. Wu, S. Mu, Qian Chen, Feng-xia Gao, Jian-Wei Wang, S. Long, Luo Li, Yang Wu, Yan Gao, Wei Xu, Xia Cai, D. Qu, Zhe-Rui Zhang, Hongqing Zhang, Na Li, Q. Gao, Guiji Zhang, Chang-long He, Wen Wang, Xiaoyun Ji, N. Tang, Zheng-Hong Yuan, You-Hua Xie, Haitao Yang, Bo Zhang, Ai-Long Huang, Ai-Shun Jin

Nature Communications

DOI

2021

Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation

S. Xia, Qiao-Shuai Lan, Yun Zhu, Chao Wang, Wei Xu, Yu-Tang Li, Lijue Wang, F. Jiao, Jie Zhou, Chen Hua, Qian Wang, Xia Cai, Yang Wu, Jie Gao, Huan Liu, Ge Sun, Jan Münch, F. Kirchhoff, Zheng-Hong Yuan, You-Hua Xie, Fei Sun, Shi-Bo Jiang, Lu Lu

Signal Transduction and Targeted Therapy

DOI

2021

Enhancement versus neutralization by SARS-CoV-2 antibodies from a convalescent donor associates with distinct epitopes on the RBD

Yunjiao Zhou, Ze-Zhong Liu, Shi-Bo Li, Wei Xu, Qianqian Zhang, I. T. Silva, Cheng Li, Yan-Ling Wu, Qing-Ling Jiang, Zhen-Mi Liu, Qiu-Jing Wang, Yu Guo, Jian-Bo Wu, Chen-jian Gu, Xia Cai, D. Qu, C. Mayer, Xiang-Xi Wang, Shi-Bo Jiang, T. Ying, Zheng-Hong Yuan, You-Hua Xie, Yu-Mei Wen, Lu Lu, Qiao Wang

Cell Reports

DOI

2021

Effect of chlorine dioxide on avian influenza A (H7N9) virus

Zhi-Ping Sun, Yun Qian, N. Ogata, Xia Cai, Wen-Dong Han, You-Hua Xie, H. Morino, Koushirou Sogawa, T. Shibata, D. Qu

Biosafety and Health

DOI

2020

A Rapid and Efficient Screening System for Neutralizing Antibodies and Its Application for SARS-CoV-2

Xiao-Jian Han, Ying-Ming Wang, Shenglong Li, Chao Hu, Ting-Ting Li, C. Gu, Kai Wang, M. Shen, Jian-Wei Wang, Jie-Li Hu, R. Wu, S. Mu, Fang Gong, Qian Chen, Feng-xia Gao, Jingjing Huang, Y. Long, F. Luo, Shu-Yi Song, S. Long, Y. Hao, Luo Li, Yang Wu, Wei Xu, Xia Cai, Q. Gao, Guiji Zhang, Chang-long He, K. Deng, L. Du, Yaru Nai, Wang Wang, You-Hua Xie, D. Qu, Ai-Long Huang, N. Tang, Ai-Shun Jin

Frontiers in Immunology

DOI

2020

Griffithsin with A Broad-Spectrum Antiviral Activity by Binding Glycans in Viral Glycoprotein Exhibits Strong Synergistic Effect in Combination with A Pan-Coronavirus Fusion Inhibitor Targeting SARS-CoV-2 Spike S2 Subunit

Yanxing Cai, Wei Xu, C. Gu, Xia Cai, D. Qu, Lu Lu, You-Hua Xie, Shi-Bo Jiang

Virologica Sinica

DOI

2020

Engineered trimeric ACE2 binds viral spike protein and locks it in “Three-up” conformation to potently inhibit SARS-CoV-2 infection

Liang Guo, W. Bi, Xin-Ling Wang, Wei Xu, R. Yan, Yuan-Yuan Zhang, Kai Zhao, Ya-Ning Li, Ming-Feng Zhang, Xia Cai, Shi-Bo Jiang, You-Hua Xie, Qiang Zhou, Lu Lu, Bo-Bo Dang

Cell Research

DOI

2020

Decoy nanoparticles protect against COVID-19 by concurrently adsorbing viruses and inflammatory cytokines

Lang Rao, S. Xia, W. Xu, Rui Tian, Guocan Yu, C. Gu, Pan Pan, Qian-Fang Meng, Xia Cai, D. Qu, Lu Lu, You-Hua Xie, Shi-Bo Jiang, X. Chen

Proceedings of the National Academy of Sciences of the United States of America

DOI

2020

The recombinant subunit vaccine RBD-Fc, consisting of SARS-CoV-2 RBD and human IgG Fc as an immunopotentiator, elicits robust neutralizing antibody responses against SARS-CoV-2 infection

Ze-Zhong Liu, Wei Xu, S. Xia, C. Gu, Xin-Ling Wang, Qian Wang, Jie Zhou, Yan-Ling Wu, Xia Cai, D. Qu, T. Ying, You-Hua Xie, Lu Lu, Zheng-Hong Yuan, Shi-Bo Jiang

DOI

2020

A key linear epitope for a potent neutralizing antibody to SARS-CoV-2 S-RBD

Ting-Ting Li, Xiao-Jian Han, Ying-Ming Wang, C. Gu, Jian-Wei Wang, Chao Hu, Shenglong Li, Kai Wang, F. Luo, Jingjing Huang, Y. Long, Shu-Yi Song, Wen Wang, Jie-Li Hu, R. Wu, S. Mu, Y. Hao, Qian Chen, Feng-xia Gao, M. Shen, S. Long, Fang Gong, Luo Li, Yang Wu, W. Xu, Xia Cai, D. Qu, Zheng-Hong Yuan, Q. Gao, Guiji Zhang, Chang-long He, Yaru Nai, K. Deng, Li Du, N. Tang, You-Hua Xie, Ai-Long Huang, Ai-Shun Jin

bioRxiv

DOI

2020

RBD-Fc-based COVID-19 vaccine candidate induces highly potent SARS-CoV-2 neutralizing antibody response

Ze-Zhong Liu, Wei Xu, S. Xia, C. Gu, Xin-Ling Wang, Qian Wang, Jie Zhou, Yan-Ling Wu, Xia Cai, D. Qu, T. Ying, You-Hua Xie, Lu Lu, Zheng-Hong Yuan, Shi-Bo Jiang

Signal Transduction and Targeted Therapy

DOI

2020

新型冠状病毒上海株(nCoV-SH01)的分离和鉴定

Rong Zhang, Zhang Ron, Zhi-Gang Yi, Zhi-Gang Yi, Yuyan Wang, Yuyan Wang, Z. Teng, Z. Teng, Wei Xu, Wei Xu, Wu Song, Wu Song, Xia Cai, Xia Cai, Zhi-Ping Sun, Zhi-Ping Sun, Chen-jian Gu, Chen-jian Gu, Yan-Qiu Zhou, Yan-Qiu Zhou, Hong-You Chen, Hong-You Chen, Rong Ye, Rong Ye, Wen-Dong Han, Wen-Dong Han, Yun-Kai Zhu, Yun-Kai Zhu, Fei Feng, Fei Feng, Fang-Hao Fang, Fang-Hao Fang, Chongshan Li, Chongshan Li, Xi Zhang, Xi Zhang, D. Qu, D. Qu, Chen-Xu Fu, Chen-Xu Fu, You-Hua Xie, You-Hua Xie, Zheng-Hong Yuan, Zheng-Hong Yuan

DOI

2020

Survival of SARS-COV-2 under liquid medium, dry filter paper and acidic conditions

Zhi-Ping Sun, Xia Cai, C. Gu, Rong Zhang, Wen-Dong Han, Yun Qian, Yuyan Wang, Wei Xu, Yang Wu, Xun-Jia Cheng, Zheng-Hong Yuan, You-Hua Xie, D. Qu

Cell Discovery

DOI

2020

The S1/S2 boundary of SARS-CoV-2 spike protein modulates cell entry pathways and transmission

Yun-Kai Zhu, Fei Feng, Gaowei Hu, Yuyan Wang, Yin Yu, Yuan-Fei Zhu, Wei Xu, Xia Cai, Zhi-Ping Sun, Wen-Dong Han, R. Ye, Hong-Jun Chen, Q. Ding, Qiliang Cai, D. Qu, You-Hua Xie, Zheng-Hong Yuan, Rong Zhang

bioRxiv

DOI

2020

Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2

Ying-Hui Liu, Gaowei Hu, Yuyan Wang, W. Ren, Xiaomin Zhao, Fansen Ji, Yun-Kai Zhu, Fei Feng, M. Gong, Xiaohui Ju, Yuan-Fei Zhu, Xia Cai, J. Lan, Jian-Ying Guo, Min Xie, Lin Dong, Zi-Hui Zhu, Jie Na, Jian-Ping Wu, Xun Lan, You-Hua Xie, Xin-Quan Wang, Zheng-Hong Yuan, Rong Zhang, Q. Ding

Proceedings of the National Academy of Sciences of the United States of America

DOI

2020

Protoporphyrin IX and verteporfin potently inhibit SARS-CoV-2 infection in vitro and in a mouse model expressing human ACE2

C. Gu, Yang Wu, Hui-Min Guo, Yuanfei Zhu, Wei Xu, Yuyan Wang, Yu Zhou, Zhi-Ping Sun, Xia Cai, Yu-Tang Li, Jing Liu, Zhong Huang, Zheng-Hong Yuan, Rong Zhang, Q. Deng, D. Qu, You-Hua Xie

Science Bulletin

DOI

2020

Stability of the COVID-19 virus under wet, dry and acidic conditions

Zhi-Ping Sun, Xia Cai, Chen-jian Gu, Rong Zhang, Wen-Dong Han, Yun Qian, Yuyan Wang, W. Xu, Yang Wu, Xun Cheng, Zheng-Hong Yuan, You-Hua Xie, D. Qu

medRxiv

DOI

2020

Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide

Fei Li, Ming Han, Peng-Fei Dai, W. Xu, Juan He, Xiaoting Tao, Yang Wu, Xinyuan Tong, Xinyi Xia, Wang-Xin Guo, Yunjiao Zhou, Yunguang Li, Yi-Qin Zhu, Xiaoyu Zhang, Zhuang Liu, Rebiguli Aji, Xia Cai, Yu-Tang Li, D. Qu, Yu Chen, Shi-Bo Jiang, Qiao Wang, H. Ji, You-Hua Xie, Yi-Hua Sun, Lu Lu, D. Gao

Nature Communications

DOI

2020

Potent antiviral effect of protoporphyrin IX and verteporfin on SARS-CoV-2 infection

C. Gu, Yang Wu, Hui-Min Guo, Yuanfei Zhu, Wei Xu, Yuyan Wang, Yu Zhou, Zhi-Ping Sun, Xia Cai, Yu-Tang Li, Jing Liu, Zhong Huang, Zheng-Hong Yuan, Rong Zhang, Q. Deng, D. Qu, You-Hua Xie

DOI

2018

Virulence and Stress Responses of Shigella flexneri Regulated by PhoP/PhoQ

Zhi-Wei Lin, Xia Cai, Ming-Liang Chen, L. Ye, Yang Wu, Xiao-Fei Wang, Zhihui Lv, Y. Shang, D. Qu

Frontiers in Microbiology

DOI

2017

第二信使分子c-di-AMP调控细菌中钾离子转运的机制

蔡霞，何进

《微生物学报》

2014

表皮葡萄球菌PhoU同源物(SERP0316)的抗体制备及免疫鉴定

韩海燕，王小飞，武有聪，许涛，刘华勇，蔡霞，瞿涤

《微生物与感染》

2013

Deletion of pic results in decreased virulence for a clinical isolate of Shigella flexneri2a from China

Junqi Zhang, Li-Sheng Qian, Yang Wu, Xia Cai, Xue-Ping Li, Xun-Jia Cheng, D. Qu

BMC Microbiology

DOI

2011

PhoP-PhoQ双组分信号转导系统调控福氏志贺菌毒力的机理研究

蔡霞

《复旦大学》

2011

The Effect of the Potential PhoQ Histidine Kinase Inhibitors on Shigella flexneri Virulence

Xia Cai, Jian Zhang, Ming-Liang Chen, Yang Wu, Xueqin Wang, Jiayu Chen, Junqi Zhang, Xu Shen, D. Qu, Hua-Liang Jiang

PLoS ONE

DOI

2010

沙门菌PhoP-PhoQ双组分信号转导系统

陈嘉瑜，蔡霞，瞿涤

《微生物与感染》

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