蒋丽丽｜广州医科大学｜学者主页

2026

Protein kinase Cι-driven macrophage infiltration mediates immunosuppression in non-small cell lung cancer.

Shichuan Hu, Zichen Zhao, Jing Zhao, Yilin Liang, Lingye Zeng, Yi-Fei Xia, Hao-Yue Guo, Lili Jiang, Yan Zhang

Cancer Letters

2025

POU6F2 promotes liver metastasis of gastric adenocarcinoma by dual mechanism of transcriptional upregulation of SNAI1 and IGF2/PI3K/AKT signaling-induced conversion of hepatic stellate cells into cancer-associated fibroblasts

Chunxiao Yang, Zhiqing Gao, Ruiming Tang, Lihuan Zhou, Ping Zhou, Wangpan Shi, Dong Ren, Han Chen, Zhuojun Zhang, Xiaoyi Xie, Jiaqian Lin, Yong-Sheng Ye, Zhengfu Feng, Xiaoli Feng, Yaoming He, Yaofeng Zhi, Dongmei Liu, Xin Zhang, Lili Jiang

British Journal of Cancer

DOI

2025

Suprabasin promotes gastric cancer liver metastasis via hepatic stellate cells-mediated EGF/CCL2/JAK2 intercellular signaling pathways

Difeng Li, Zhiqing Gao, Zhuojun Zhang, Han Chen, Ruiming Tang, Lihuan Zhou, Yingmin Ye, Jiaqian Lin, Ping Zhou, Chanjuan Wang, Xiaoli Feng, Yaoming He, Zijie Meng, Mingzhu Zheng, Wenjie Lu, Zhengfu Feng, Lan Wang, Yuanyuan Pei, Jianan Yang, Tianyu Tao, Xin Zhang, Lili Jiang

Oncogene

DOI

2024

中国复发性或转移性头颈部鳞状细胞癌患者中PD-L1的表达（EXCEED研究）：一项多中心、回顾性研究

Haizhen Lu, Dong Kuang, Ping Zhou, Jing Zeng, Qingxin Xia, Jian Wang, Pei Duan, Lili Jiang, Shengbing Zang, Yiping Jin, Xiangnan Jiang, Jielin Li, Wenmin Tang, Jiansong Zhou, Jihua Chen, Jianming Ying, 郭晔

《癌症》

2023

Peptidase inhibitor (PI16) impairs bladder cancer metastasis by inhibiting NF-κB activation via disrupting multiple-site ubiquitination of NEMO

Xiangqin Kuang, Zhuojun Zhang, Difeng Li, Wenhao Bao, Jinyuan Pan, Ping Zhou, Han Chen, Zhiqing Gao, Xiaoyi Xie, Chunxiao Yang, Ge Zhu, Zhongqiu Zhou, Ruiming Tang, Zhengfu Feng, Lihuan Zhou, Xiaoli Feng, Lan Wang, Jianan Yang, Lili Jiang

Cellular & Molecular Biology Letters

DOI

2022

Extracellular vesicles-transferred SBSN drives glioma aggressiveness by activating NF-κB via ANXA1-dependent ubiquitination of NEMO

Han Chen, Xuhong Chen, Zhuojun Zhang, Wenhao Bao, Zhiqing Gao, Difeng Li, Xiaoyi Xie, Ping Zhou, Chunxiao Yang, Zhongqiu Zhou, Jinyuan Pan, Xiangqin Kuang, Ruiming Tang, Zhengfu Feng, Lihuan Zhou, Dachun Zhu, Jianan Yang, Lan Wang, Hongbiao Huang, Daolin Tang, Jinbao Liu, Lili Jiang

Oncogene

DOI

2022

SBSN drives bladder cancer metastasis via EGFR/SRC/STAT3 signalling

Zhongqiu Zhou, Zhuojun Zhang, Han Chen, Wenhao Bao, Xiangqin Kuang, Ping Zhou, Zhiqing Gao, Difeng Li, Xiaoyi Xie, Chunxiao Yang, Xuhong Chen, Jinyuan Pan, Ruiming Tang, Zhengfu Feng, Lihuan Zhou, Lan Wang, Jianan Yang, Lili Jiang

British Journal of Cancer

DOI

2022

Increased MCL-1 synthesis promotes irradiation-induced nasopharyngeal carcinoma radioresistance via regulation of the ROS/AKT loop

Yingying Liang, Feiyu Niu, Anan Xu, Lili Jiang, Chunshan Liu, Huiping Liang, Yu‐Fan Huang, Xunfan Shao, Zhi-Wen Mo, Yawei Yuan

Cell Death and Disease

DOI

2022

Molecular mechanism and potential therapeutic targets of liver metastasis from gastric cancer

Difeng Li, Xin Zhang, Lili Jiang

Frontiers in Oncology

DOI

2021

Correction to: Antagonizing miR-455-3p inhibits chemoresistance and aggressiveness in esophageal squamous cell carcinoma

Aibin Liu, Jinrong Zhu, Geyan Wu, Lixue Cao, Zhanyao Tan, Shuxia Zhang, Lili Jiang, Jueheng Wu, Mengfeng Li, Libing Song, Jun Li

Molecular Cancer

DOI

2021

ACBD3 is up-regulated in gastric cancer and promotes cell cycle G1-to-S transition in an AKT-dependent manner

Yingchun Zheng, Yuanyuan Pei, Ruiming Tang, Xiulan Zhou, Zhengfu Feng, Difeng Li, Han Chen, Zhi Rong Zeng, Lili Jiang, Junchao Cai, Pu Mao, Lan Wang

Experimental Cell Research

DOI

2021

The deubiquitinating enzyme USP15 stabilizes ERα and promotes breast cancer progression

Xiaohong Xia, Chuyi Huang, Yuning Liao, Yuan Liu, Jinchan He, Zhenlong Shao, Tumei Hu, Cuifu Yu, Lili Jiang, Jinbao Liu, Hongbiao Huang

Cell Death and Disease

DOI

2020

RASSF1A inhibits PDGFB-driven malignant phenotypes of nasopharyngeal carcinoma cells in a YAP1-dependent manner

Yingying Liang, Xubin Deng, Xiantao Lin, Lili Jiang, Xiaoting Huang, Zhi-Wen Mo, Yawei Yuan, Muy‐Teck Teh

Cell Death and Disease

DOI

2020

NCAPG confers trastuzumab resistance via activating SRC/STAT3 signaling pathway in HER2-positive breast cancer

Lili Jiang, Liangliang Ren, Han Chen, Jinyuan Pan, Zhuojun Zhang, Xiangqin Kuang, Xuhong Chen, Wenhao Bao, Chun‐Yu Lin, Zhongqiu Zhou, Danping Huang, Jianan Yang, Hongbiao Huang, Lan Wang, Ning Hou, Libing Song

Cell Death and Disease

DOI

2020

Targeting SKP2/Bcr-Abl pathway with Diosmetin suppresses chronic myeloid leukemia proliferation

Yuan Liu, Zhenlong Shao, Yuning Liao, Xiaohong Xia, Chuyi Huang, Jinchan He, Tumei Hu, Cuifu Yu, Lili Jiang, Jinbao Liu, Hongbiao Huang

European Journal of Pharmacology

DOI

2020

Targeting GRP78-dependent AR-V7 protein degradation overcomes castration-resistance in prostate cancer therapy

Yuning Liao, Yuan Liu, Xiaohong Xia, Zhenlong Shao, Chuyi Huang, Jinchan He, Lili Jiang, Daolin Tang, Jinbao Liu, Hongbiao Huang

Theranostics

DOI

2019

MiR-454-3p-Mediated Wnt/β-catenin Signaling Antagonists Suppression Promotes Breast Cancer Metastasis

Liangliang Ren, Han Chen, Junwei Song, Xuhong Chen, Chun‐Yu Lin, Xiaolan Zhang, Ning Hou, Jinyuan Pan, Zhongqiu Zhou, Lan Wang, Danping Huang, Jianan Yang, Yingying Liang, Jun Li, Hongbiao Huang, Lili Jiang

Theranostics

DOI

2019

Deubiquitination and stabilization of estrogen receptor α by ubiquitin-specific protease 7 promotes breast tumorigenesis

Xiaohong Xia, Yuning Liao, Chuyi Huang, Yuan Liu, Jinchan He, Zhenlong Shao, Lili Jiang, Q. Ping Dou, Jinbao Liu, Hongbiao Huang

Cancer Letters

DOI

2019

Inhibition of USP14 enhances the sensitivity of breast cancer to enzalutamide

Xiaohong Xia, Chuyi Huang, Yuning Liao, Yuan Liu, Jinchan He, Zhiqiang Guo, Lili Jiang, Xuejun Wang, Jinbao Liu, Hongbiao Huang

Journal of Experimental & Clinical Cancer Research

DOI

2019

Synergistic effects of gefitinib and thalidomide treatment on EGFR-TKI-sensitive and -resistant NSCLC

Xiaohong Xia, Yuan Liu, Yuning Liao, Zhiqiang Guo, Chuyi Huang, Fangcheng Zhang, Lili Jiang, Xuejun Wang, Jinbao Liu, Hongbiao Huang

European Journal of Pharmacology

DOI

2019

USP10 modulates the SKP2/Bcr-Abl axis via stabilizing SKP2 in chronic myeloid leukemia

Yuning Liao, Ningning Liu, Xiaohong Xia, Zhiqiang Guo, Yanling Li, Lili Jiang, Ruiqing Zhou, Daolin Tang, Hongbiao Huang, Jinbao Liu

Cell Discovery

DOI

2019

Inhibition of EGFR signaling with Spautin-1 represents a novel therapeutics for prostate cancer

Yuning Liao, Zhiqiang Guo, Xiaohong Xia, Yuan Liu, Chuyi Huang, Lili Jiang, Xuejun Wang, Jinbao Liu, Hongbiao Huang

Journal of Experimental & Clinical Cancer Research

DOI

2019

Overexpression of PIMREG promotes breast cancer aggressiveness via constitutive activation of NF-κB signaling

Lili Jiang, Liangliang Ren, Xiaolan Zhang, Han Chen, Xuhong Chen, Chun‐Yu Lin, Lan Wang, Ning Hou, Jinyuan Pan, Zhongqiu Zhou, Hongbiao Huang, Danping Huang, Jianan Yang, Yingying Liang, Jun Li

EBioMedicine

DOI

2019

Auranofin lethality to prostate cancer includes inhibition of proteasomal deubiquitinases and disrupted androgen receptor signaling

Ningning Liu, Zhiqiang Guo, Xiaohong Xia, Yuning Liao, Fangcheng Zhang, Chuyi Huang, Yuan Liu, Xiumei Deng, Lili Jiang, Xuejun Wang, Jinbao Liu, Hongbiao Huang

European Journal of Pharmacology

DOI

2019

Parkin Facilitates Proteasome Inhibitor-Induced Apoptosis via Suppression of NF-κB Activity in Hepatocellular Carcinoma

Xiaolan Zhang, Chun‐Yu Lin, Junwei Song, Han Chen, Xuhong Chen, Liangliang Ren, Zhongqiu Zhou, Jinyuan Pan, Zhenjun Yang, Wenhao Bao, Xueping Ke, Jianan Yang, Yingying Liang, Hongbiao Huang, Daolin Tang, Lili Jiang, Jinbao Liu

Cell Death and Disease

DOI

2018

Transcription factor AP-4 promotes tumorigenic capability and activates the Wnt/β-catenin pathway in hepatocellular carcinoma

Junwei Song, Chan Xie, Lili Jiang, Geyan Wu, Jinrong Zhu, Shuxia Zhang, Miaoling Tang, Libing Song, Jun Li

Theranostics

DOI

2018

Targeting proteasome-associated deubiquitinases as a novel strategy for the treatment of estrogen receptor-positive breast cancer

Xiaohong Xia, Yuning Liao, Zhiqiang Guo, Yanling Li, Lili Jiang, Fangcheng Zhang, Chuyi Huang, Yuan Liu, Xuejun Wang, Ningning Liu, Jinbao Liu, Hongbiao Huang

Oncogenesis

DOI

2018

Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination

Yuning Liao, Xiaohong Xia, Ningning Liu, Jianyu Cai, Zhiqiang Guo, Yanling Li, Lili Jiang, Q. Ping Dou, Daolin Tang, Hongbiao Huang, Jinbao Liu

Oncogene

DOI

2017

Nucleolar and spindle associated protein 1 promotes the aggressiveness of astrocytoma by activating the Hedgehog signaling pathway

Xianqiu Wu, Benke Xu, Chao‐Chun Yang, Wentao Wang, Dequan Zhong, Zhanzheng Zhao, Longshuang He, Yuanjun Hu, Lili Jiang, Jun Li, Libing Song, Wei Zhang

Journal of Experimental & Clinical Cancer Research

DOI

2017

Antagonizing miR-455-3p inhibits chemoresistance and aggressiveness in esophageal squamous cell carcinoma

Aibin Liu, Jinrong Zhu, Geyan Wu, Lixue Cao, Zhanyao Tan, Shuxia Zhang, Lili Jiang, Jueheng Wu, Mengfeng Li, Libing Song, Jun Li

Molecular Cancer

DOI

2017

Overexpression of SMC4 activates TGFβ/Smad signaling and promotes aggressive phenotype in glioma cells

Lili Jiang, Jianwen Zhou, Dequan Zhong, Y Zhou, W Zhang, W Wu, Zongqing Zhao, W Wang, Wenzhong Xu, Lu He, Y Ma, Yingjie Hu, W Zhang, Jingjia Li

Oncogenesis

DOI

2017

Repurposing an antidandruff agent to treating cancer: zinc pyrithione inhibits tumor growthviatargeting proteasome-associated deubiquitinases

Chong Zhao, Xin Chen, Changshan Yang, Dan Zang, Xiaoying Lan, Siyan Liao, Peiquan Zhang, Jinjie Wu, Xiaofen Li, Ningning Liu, Yuning Liao, Hongbiao Huang, Xianping Shi, Lili Jiang, Xiuhua Liu, Q. Ping Dou, Xuejun Wang, Jinbao Liu

Oncotarget

DOI

2016

Platinum-containing compound platinum pyrithione is stronger and safer than cisplatin in cancer therapy

Chong Zhao, Xin Chen, Dan Zang, Xiaoying Lan, Siyan Liao, Changshan Yang, Peiquan Zhang, Jinjie Wu, Xiaofen Li, Ningning Liu, Yuning Liao, Hongbiao Huang, Xianping Shi, Lili Jiang, Xiuhua Liu, Zhimin He, Xuejun Wang, Jinbao Liu

Biochemical Pharmacology

DOI

2016

A microRNA-mediated decrease in eukaryotic initiation factor 2α promotes cell survival during PS-341 treatment

Lili Jiang, Dan Zang, Songgang Yi, Xiaofen Li, Changshan Yang, Xiaoxian Dong, Chong Zhao, Xiaoying Lan, Xin Chen, Shouting Liu, Ningning Liu, Hongbiao Huang, Xianping Shi, Xuejun Wang, Jinbao Liu

Scientific Reports

DOI

2016

miR-892b Silencing Activates NF-κB and Promotes Aggressiveness in Breast Cancer

Lili Jiang, Liang Yu, Xin Zhang, Fangyong Lei, Lan Wang, Xiangxia Liu, Shu Wu, Jinrong Zhu, Geyan Wu, Lixue Cao, Aibin Liu, Libing Song, Jun Li

Cancer Research

DOI

2015

miR-93 Promotes Cell Proliferation in Gliomas through Activation of PI3K/Akt Signaling Pathway

Lili Jiang, Chanjuan Wang, Fangyong Lei, Longjuan Zhang, Xin Zhang, Aibin Liu, Geyan Wu, Jinrong Zhu, Libing Song

Oncotarget

DOI

2014

Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth

Ningning Liu, Xiaofen Li, Hongbiao Huang, Chong Zhao, Chong Zhao, Siyan Liao, Changshan Yang, Shouting Liu, Wenbin Song, Xiaoying Lan, Xiaoying Lan, Xin Chen, Songgang Yi, Li Xu, Lili Jiang, Canguo Zhao, Canguo Zhao, Xiaoxian Dong, Ping Zhou, Shujue Li, Shunqing Wang, Xianping Shi, Ping Q. Dou, Xuejun Wang, Jinbao Liu

Oncotarget

DOI

2012

Gambogic Acid Is a Tissue-Specific Proteasome Inhibitor In Vitro and In Vivo

Xiaofen Li, Shouting Liu, Hongbiao Huang, Ningning Liu, Chong Zhao, Siyan Liao, Changshan Yang, Yurong Liu, Canguo Zhao, Shujue Li, Xiaoyu Lu, Chunjiao Liu, Lixia Guan, Kai Zhao, Xiaoqing Shi, Wenbin Song, Ping Zhou, Xiaoxian Dong, Haiping Guo, Guanmei Wen, Chang-E Zhang, Lili Jiang, Ning‐Fang Ma, Bing Li, Shunqing Wang, Huo Tan, Xuejun Wang, Q. Ping Dou, Jinbao Liu

Cell Reports

DOI

精选作品

期刊论文

Protein kinase Cι-driven macrophage infiltration mediates immunosuppression in non-small cell lung cancer.

POU6F2 promotes liver metastasis of gastric adenocarcinoma by dual mechanism of transcriptional upregulation of SNAI1 and IGF2/PI3K/AKT signaling-induced conversion of hepatic stellate cells into cancer-associated fibroblasts

Suprabasin promotes gastric cancer liver metastasis via hepatic stellate cells-mediated EGF/CCL2/JAK2 intercellular signaling pathways

中国复发性或转移性头颈部鳞状细胞癌患者中PD-L1的表达（EXCEED研究）：一项多中心、回顾性研究

Peptidase inhibitor (PI16) impairs bladder cancer metastasis by inhibiting NF-κB activation via disrupting multiple-site ubiquitination of NEMO

Extracellular vesicles-transferred SBSN drives glioma aggressiveness by activating NF-κB via ANXA1-dependent ubiquitination of NEMO

SBSN drives bladder cancer metastasis via EGFR/SRC/STAT3 signalling

Increased MCL-1 synthesis promotes irradiation-induced nasopharyngeal carcinoma radioresistance via regulation of the ROS/AKT loop

Molecular mechanism and potential therapeutic targets of liver metastasis from gastric cancer

Correction to: Antagonizing miR-455-3p inhibits chemoresistance and aggressiveness in esophageal squamous cell carcinoma

ACBD3 is up-regulated in gastric cancer and promotes cell cycle G1-to-S transition in an AKT-dependent manner

The deubiquitinating enzyme USP15 stabilizes ERα and promotes breast cancer progression

RASSF1A inhibits PDGFB-driven malignant phenotypes of nasopharyngeal carcinoma cells in a YAP1-dependent manner

NCAPG confers trastuzumab resistance via activating SRC/STAT3 signaling pathway in HER2-positive breast cancer

Targeting SKP2/Bcr-Abl pathway with Diosmetin suppresses chronic myeloid leukemia proliferation

Targeting GRP78-dependent AR-V7 protein degradation overcomes castration-resistance in prostate cancer therapy

MiR-454-3p-Mediated Wnt/β-catenin Signaling Antagonists Suppression Promotes Breast Cancer Metastasis

Deubiquitination and stabilization of estrogen receptor α by ubiquitin-specific protease 7 promotes breast tumorigenesis

Inhibition of USP14 enhances the sensitivity of breast cancer to enzalutamide

Synergistic effects of gefitinib and thalidomide treatment on EGFR-TKI-sensitive and -resistant NSCLC

USP10 modulates the SKP2/Bcr-Abl axis via stabilizing SKP2 in chronic myeloid leukemia

Inhibition of EGFR signaling with Spautin-1 represents a novel therapeutics for prostate cancer

Overexpression of PIMREG promotes breast cancer aggressiveness via constitutive activation of NF-κB signaling

Auranofin lethality to prostate cancer includes inhibition of proteasomal deubiquitinases and disrupted androgen receptor signaling

Parkin Facilitates Proteasome Inhibitor-Induced Apoptosis via Suppression of NF-κB Activity in Hepatocellular Carcinoma

Transcription factor AP-4 promotes tumorigenic capability and activates the Wnt/β-catenin pathway in hepatocellular carcinoma

Targeting proteasome-associated deubiquitinases as a novel strategy for the treatment of estrogen receptor-positive breast cancer

Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination

Nucleolar and spindle associated protein 1 promotes the aggressiveness of astrocytoma by activating the Hedgehog signaling pathway

Antagonizing miR-455-3p inhibits chemoresistance and aggressiveness in esophageal squamous cell carcinoma

Overexpression of SMC4 activates TGFβ/Smad signaling and promotes aggressive phenotype in glioma cells

Repurposing an antidandruff agent to treating cancer: zinc pyrithione inhibits tumor growthviatargeting proteasome-associated deubiquitinases

Platinum-containing compound platinum pyrithione is stronger and safer than cisplatin in cancer therapy

A microRNA-mediated decrease in eukaryotic initiation factor 2α promotes cell survival during PS-341 treatment

miR-892b Silencing Activates NF-κB and Promotes Aggressiveness in Breast Cancer

miR-93 Promotes Cell Proliferation in Gliomas through Activation of PI3K/Akt Signaling Pathway

Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth

Gambogic Acid Is a Tissue-Specific Proteasome Inhibitor In Vitro and In Vivo

书籍章节

Analysis of Protein Degradation in Ferroptosis

研究方向